#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O70585 uniprotkb:P33175 intact:EBI-349714|uniprotkb:O70563|uniprotkb:Q9CTZ1|uniprotkb:E9Q0F2|ensembl:ENSMUSP00000126194 intact:EBI-349710|uniprotkb:Q5DTP1|uniprotkb:Q6PDY7|uniprotkb:Q9Z2F9|ensembl:ENSMUSP00000096775|ensembl:ENSMUSP00000151402 psi-mi:dtnb_mouse(display_long)|uniprotkb:Dtnb(gene name)|psi-mi:Dtnb(display_short)|uniprotkb:Beta-dystrobrevin(gene name synonym) psi-mi:kif5a_mouse(display_long)|uniprotkb:Kif5a(gene name)|psi-mi:Kif5a(display_short)|uniprotkb:Kiaa4086(gene name synonym)|uniprotkb:Kif5(gene name synonym)|uniprotkb:Neuronal kinesin heavy chain(gene name synonym)|uniprotkb:Kinesin heavy chain neuron-specific 1(gene name synonym)|uniprotkb:Nkhc1(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Fratini et al. (2012) mint:fj-12-0502.r1|pubmed:22978324|mint:MINT-8392493 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8053372|mint:MINT-8392735 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001155937.1|ensembl:ENSMUSG00000071454(gene)|ensembl:ENSMUST00000164578(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0045202"(synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|mint:MINT-8392738(identity) refseq:NP_001034089.1|refseq:NP_032473.2|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:P33175|reactome:R-MMU-2132295|reactome:R-MMU-5625970|reactome:R-MMU-6811434|reactome:R-MMU-983189|ensembl:ENSMUSG00000074657(gene)|ensembl:ENSMUST00000099172(transcript)|ensembl:ENSMUST00000217895(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|mint:MINT-8392737(identity) - - - comment:homomint|comment:mint|figure legend:f3c f4 f8c taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/09/12 2014/10/16 rogid:5BxmvYreKnYpuU7c0saCR88ShhU10090 rogid:otK0LxjRwOuSLqL6iOEI+7BY+SI10090 intact-crc:98C502FF310706BA|rigid:G6jZenSFvG+zkgUWUJIBwpUkI2Q false binding-associated region:1-352(MINT-8392754)|glutathione s tranferase tag:?-?(MINT-8392748) binding-associated region:804-1027(MINT-8392743)|glutathione s tranferase tag:?-?(MINT-8392740) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O70585 uniprotkb:Q6QLM7 intact:EBI-349714|uniprotkb:O70563|uniprotkb:Q9CTZ1|uniprotkb:E9Q0F2|ensembl:ENSMUSP00000126194 intact:EBI-8053424|intact:UNK-5485260 psi-mi:dtnb_mouse(display_long)|uniprotkb:Dtnb(gene name)|psi-mi:Dtnb(display_short)|uniprotkb:Beta-dystrobrevin(gene name synonym) psi-mi:kif5a_rat(display_long)|uniprotkb:Kinesin heavy chain neuron-specific 1(gene name synonym)|uniprotkb:Neuronal kinesin heavy chain(gene name synonym)|uniprotkb:Kif5a(gene name)|psi-mi:Kif5a(display_short) psi-mi:"MI:0096"(pull down) Fratini et al. (2012) mint:fj-12-0502.r1|pubmed:22978324|mint:MINT-8392493 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8053419|mint:MINT-8392923 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001155937.1|ensembl:ENSMUSG00000071454(gene)|ensembl:ENSMUST00000164578(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0045202"(synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|mint:MINT-8392925(identity) rgd:1303035|refseq:NP_997688.1|mint:Q6QLM7|dip:DIP-46364N|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021794"(thalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048666"(neuron development)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904647"(response to rotenone)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR027640|interpro:IPR036961|rcsb pdb:2KIN|interpro:IPR027417|rcsb pdb:3KIN|reactome:R-RNO-2132295|reactome:R-RNO-5625970|reactome:R-RNO-6811434|reactome:R-RNO-983189|go:"GO:0000932"(P-body)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|mint:MINT-8392926(identity) - - comment:mint|comment:homomint|function:"Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL)" comment:homomint|figure legend:f7|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/09/12 2015/07/27 rogid:5BxmvYreKnYpuU7c0saCR88ShhU10090 rogid:8Rs5XnQSfYtBkTw31UqIBAtb/wY10116 intact-crc:73CED64DF86C2499|rigid:ZFja/dKF6vgL92TD/H42uLiv0r4 false glutathione s tranferase tag:?-?(MINT-8392927)|binding-associated region:?-?(MINT-8392930)|mutation decreasing interaction:11-11(MINT-8392932) - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0113"(western blot) uniprotkb:O70585 uniprotkb:D3ZMX6 intact:EBI-349714|uniprotkb:O70563|uniprotkb:Q9CTZ1|uniprotkb:E9Q0F2|ensembl:ENSMUSP00000126194 intact:EBI-8053405|intact:MINT-8392941|ensembl:ENSRNOP00000027561 psi-mi:dtnb_mouse(display_long)|uniprotkb:Dtnb(gene name)|psi-mi:Dtnb(display_short)|uniprotkb:Beta-dystrobrevin(gene name synonym) psi-mi:d3zmx6_rat(display_long)|uniprotkb:Sntb2(gene name)|psi-mi:Sntb2(display_short) psi-mi:"MI:0096"(pull down) Fratini et al. (2012) mint:fj-12-0502.r1|pubmed:22978324|mint:MINT-8392493 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8053419|mint:MINT-8392923 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001155937.1|ensembl:ENSMUSG00000071454(gene)|ensembl:ENSMUST00000164578(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0045202"(synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|mint:MINT-8392925(identity) refseq:NP_001162145.1|rgd:1592340|ensembl:ENSRNOG00000020344(gene)|ensembl:ENSRNOT00000027561(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028550|interpro:IPR036034|interpro:IPR041428|mint:MINT-8392952(identity) - - comment:mint|comment:homomint comment:homomint|figure legend:f7|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/09/12 2015/07/27 rogid:5BxmvYreKnYpuU7c0saCR88ShhU10090 rogid:ndGQjEEgYPSmwe7PE4y+v9jhqZI10116 intact-crc:73CED64DF86C2499|rigid:ZFja/dKF6vgL92TD/H42uLiv0r4 false glutathione s tranferase tag:?-?(MINT-8392927)|binding-associated region:?-?(MINT-8392930)|mutation decreasing interaction:11-11(MINT-8392932) - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0113"(western blot)