#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P9WJG3	uniprotkb:P9WGY9	intact:EBI-6421028|uniprotkb:O53568|uniprotkb:F2GJS9|uniprotkb:Q7D585|uniprotkb:L0TFY0	intact:EBI-6419676|uniprotkb:P0A680|uniprotkb:O08406|uniprotkb:P47766|uniprotkb:Q53424|uniprotkb:Q59564|uniprotkb:Q9X6Q3|uniprotkb:Q9X6U9|uniprotkb:Q9XC82|uniprotkb:Q9XC83|uniprotkb:Q9XC84|uniprotkb:Q9XC85|uniprotkb:L0T4D5	psi-mi:card_myctu(display_long)|uniprotkb:carD(gene name)|psi-mi:carD(display_short)|uniprotkb:Rv3583c(locus name)	psi-mi:rpob_myctu(display_long)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:MTCI376.08c(orf name)|uniprotkb:Rv0667(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Weiss et al. (2012)	pubmed:22904282|imex:IM-18475	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6419751|mpidb:MPIDB-INT-1936|imex:IM-18475-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4ILU|rcsb pdb:4MFR|go:"GO:0015968"(stringent response)|go:"GO:0040009"(regulation of growth rate)|rcsb pdb:4KMC|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0|refseq:WP_003419482.1|interpro:IPR003711(Transcription factor CarD)|refseq:NP_218100.1|rcsb pdb:4KBM|interpro:IPR042215|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|interpro:IPR036101	rcsb pdb:6TYE|rcsb pdb:6TYF|rcsb pdb:6TYG|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046677"(response to antibiotic)|rcsb pdb:6BZO|rcsb pdb:6C04|rcsb pdb:6C05|rcsb pdb:6C06|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6FBV|rcsb pdb:5UH9|rcsb pdb:5UHA|rcsb pdb:5UHB|rcsb pdb:5UHC|rcsb pdb:5UHD|rcsb pdb:5UHE|rcsb pdb:5UHF|rcsb pdb:5UHG|refseq:NP_215181.1|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR019462|rcsb pdb:5UH5|rcsb pdb:5UH6|rcsb pdb:5UH8|rcsb pdb:4KBJ|rcsb pdb:4KBM|rcsb pdb:5ZX2|rcsb pdb:5ZX3|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|rcsb pdb:6M7J|interpro:IPR037033|interpro:IPR037034|rcsb pdb:6JCX|rcsb pdb:6JCY|interpro:IPR042107|rcsb pdb:6DV9|rcsb pdb:6DVB|rcsb pdb:6DVC|rcsb pdb:6DVD|rcsb pdb:6DVE|reactome:R-HSA-9639775|rcsb pdb:6KON|rcsb pdb:6KOO|rcsb pdb:6KOP|rcsb pdb:6KOQ	-	crc64:15F27E0732FD6AD7	caution:This sequence has been withdrawn from Uniprot.|crc64:3DA88DEC6A7DF661	figure legend:figure 2D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:1773(myctx)|taxid:1773(Mycobacterium tuberculosis)	-	2012/11/30	2014/10/16	rogid:v2h+wJJmq9HObjLJEmmAcQjWdKg83332	rogid:GaL4H2m+CFelUZAX0cgfkrQtpiY83332	intact-crc:1C123088EB8F1E27|rigid:hvxS7APf+PJsketuzdyT+S4BXtw	false	ha tag:?-?|mutation decreasing interaction strength:47-47|mutation decreasing interaction strength:25-25	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P9WJG3	uniprotkb:P9WGY9	intact:EBI-6421028|uniprotkb:O53568|uniprotkb:F2GJS9|uniprotkb:Q7D585|uniprotkb:L0TFY0	intact:EBI-6419676|uniprotkb:P0A680|uniprotkb:O08406|uniprotkb:P47766|uniprotkb:Q53424|uniprotkb:Q59564|uniprotkb:Q9X6Q3|uniprotkb:Q9X6U9|uniprotkb:Q9XC82|uniprotkb:Q9XC83|uniprotkb:Q9XC84|uniprotkb:Q9XC85|uniprotkb:L0T4D5	psi-mi:card_myctu(display_long)|uniprotkb:carD(gene name)|psi-mi:carD(display_short)|uniprotkb:Rv3583c(locus name)	psi-mi:rpob_myctu(display_long)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:MTCI376.08c(orf name)|uniprotkb:Rv0667(locus name)	psi-mi:"MI:0010"(beta galactosidase complementation)	Weiss et al. (2012)	pubmed:22904282|imex:IM-18475	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6419724|mpidb:MPIDB-INT-1933|imex:IM-18475-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4ILU|rcsb pdb:4MFR|go:"GO:0015968"(stringent response)|go:"GO:0040009"(regulation of growth rate)|rcsb pdb:4KMC|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0|refseq:WP_003419482.1|interpro:IPR003711(Transcription factor CarD)|refseq:NP_218100.1|rcsb pdb:4KBM|interpro:IPR042215|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|interpro:IPR036101	rcsb pdb:6TYE|rcsb pdb:6TYF|rcsb pdb:6TYG|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046677"(response to antibiotic)|rcsb pdb:6BZO|rcsb pdb:6C04|rcsb pdb:6C05|rcsb pdb:6C06|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6FBV|rcsb pdb:5UH9|rcsb pdb:5UHA|rcsb pdb:5UHB|rcsb pdb:5UHC|rcsb pdb:5UHD|rcsb pdb:5UHE|rcsb pdb:5UHF|rcsb pdb:5UHG|refseq:NP_215181.1|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR019462|rcsb pdb:5UH5|rcsb pdb:5UH6|rcsb pdb:5UH8|rcsb pdb:4KBJ|rcsb pdb:4KBM|rcsb pdb:5ZX2|rcsb pdb:5ZX3|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|rcsb pdb:6M7J|interpro:IPR037033|interpro:IPR037034|rcsb pdb:6JCX|rcsb pdb:6JCY|interpro:IPR042107|rcsb pdb:6DV9|rcsb pdb:6DVB|rcsb pdb:6DVC|rcsb pdb:6DVD|rcsb pdb:6DVE|reactome:R-HSA-9639775|rcsb pdb:6KON|rcsb pdb:6KOO|rcsb pdb:6KOP|rcsb pdb:6KOQ	-	crc64:15F27E0732FD6AD7	caution:This sequence has been withdrawn from Uniprot.|crc64:3DA88DEC6A7DF661	figure legend:figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:1773(myctx)|taxid:1773(Mycobacterium tuberculosis)	-	2012/11/30	2014/10/16	rogid:v2h+wJJmq9HObjLJEmmAcQjWdKg83332	rogid:GaL4H2m+CFelUZAX0cgfkrQtpiY83332	intact-crc:A9C175E9D12A10F0|rigid:hvxS7APf+PJsketuzdyT+S4BXtw	false	sufficient binding region:1-66	mutation disrupting interaction:138-138|sufficient binding region:379-440,52-178|mutation decreasing interaction:149-149|mutation disrupting interaction:147-147|mutation:148-148	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WGY9	uniprotkb:P9WMQ5	intact:EBI-6419676|uniprotkb:P0A680|uniprotkb:O08406|uniprotkb:P47766|uniprotkb:Q53424|uniprotkb:Q59564|uniprotkb:Q9X6Q3|uniprotkb:Q9X6U9|uniprotkb:Q9XC82|uniprotkb:Q9XC83|uniprotkb:Q9XC84|uniprotkb:Q9XC85|uniprotkb:L0T4D5	intact:EBI-6419700|uniprotkb:P64326|uniprotkb:P96380|uniprotkb:L0T5H3	psi-mi:rpob_myctu(display_long)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:MTCI376.08c(orf name)|uniprotkb:Rv0667(locus name)	psi-mi:mfd_myctu(display_long)|uniprotkb:mfd(gene name)|psi-mi:mfd(display_short)|uniprotkb:MTCY10G2.29c(orf name)|uniprotkb:Rv1020(locus name)	psi-mi:"MI:0010"(beta galactosidase complementation)	Weiss et al. (2012)	pubmed:22904282|imex:IM-18475	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6419707|mpidb:MPIDB-INT-1934|imex:IM-18475-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6TYE|rcsb pdb:6TYF|rcsb pdb:6TYG|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046677"(response to antibiotic)|rcsb pdb:6BZO|rcsb pdb:6C04|rcsb pdb:6C05|rcsb pdb:6C06|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6FBV|rcsb pdb:5UH9|rcsb pdb:5UHA|rcsb pdb:5UHB|rcsb pdb:5UHC|rcsb pdb:5UHD|rcsb pdb:5UHE|rcsb pdb:5UHF|rcsb pdb:5UHG|refseq:NP_215181.1|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR019462|rcsb pdb:5UH5|rcsb pdb:5UH6|rcsb pdb:5UH8|rcsb pdb:4KBJ|rcsb pdb:4KBM|rcsb pdb:5ZX2|rcsb pdb:5ZX3|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|rcsb pdb:6M7J|interpro:IPR037033|interpro:IPR037034|rcsb pdb:6JCX|rcsb pdb:6JCY|interpro:IPR042107|rcsb pdb:6DV9|rcsb pdb:6DVB|rcsb pdb:6DVC|rcsb pdb:6DVD|rcsb pdb:6DVE|reactome:R-HSA-9639775|rcsb pdb:6KON|rcsb pdb:6KOO|rcsb pdb:6KOP|rcsb pdb:6KOQ	go:"GO:0000716"(transcription-coupled nucleotide-excision repair, DNA damage recognition)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043175"(RNA polymerase core enzyme binding)|refseq:WP_003405273.1|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003711(Transcription factor CarD)|interpro:IPR004576(Transcription-repair coupling factor)|interpro:IPR005118(TRCF)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|refseq:NP_215536.1|interpro:IPR027417|interpro:IPR036101|interpro:IPR037235|interpro:IPR041471|rcsb pdb:6ACA	-	caution:This sequence has been withdrawn from Uniprot.|crc64:3DA88DEC6A7DF661	-	figure legend:figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:1773(myctx)|taxid:1773(Mycobacterium tuberculosis)	-	2012/11/30	2014/10/16	rogid:GaL4H2m+CFelUZAX0cgfkrQtpiY83332	rogid:iCR8t0vwWrhWQDJn+Iv6hzJXdrM83332	intact-crc:20CF36FAABC793F2|rigid:X+pvQQSduKJ5t8xgXaqUZo3SYc0	false	mutation disrupting interaction:147-147|mutation decreasing interaction strength:149-149|fusion protein:52-440|mutation:148-148|mutation disrupting interaction:138-138	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)