#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P0ABG4	uniprotkb:P56976	intact:EBI-1214767|uniprotkb:P16457|ensemblbacteria:AAC73200|ensemblbacteria:BAB96657	intact:EBI-6419495|ensemblbacteria:AAT48132|ensemblbacteria:BAE76483|uniprotkb:Q2MB73	psi-mi:ftsw_ecoli(display_long)|uniprotkb:ftsW(gene name)|psi-mi:ftsW(display_short)|uniprotkb:Cell division protein FtsW(gene name synonym)|uniprotkb:Cell wall polymerase(gene name synonym)|uniprotkb:Lipid II flippase FtsW(gene name synonym)|uniprotkb:Peptidoglycan polymerase(gene name synonym)|uniprotkb:JW0087(locus name)|uniprotkb:b0089(locus name)	psi-mi:blr_ecoli(display_long)|uniprotkb:blr(gene name)|psi-mi:blr(display_short)|uniprotkb:Beta-lactam resistance protein(gene name synonym)|uniprotkb:JW5963(locus name)|uniprotkb:b4409(locus name)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Karimova et al. (2012)	pubmed:22885295|imex:IM-18476	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6421263|mpidb:MPIDB-INT-1948|imex:IM-18476-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_414631.1|refseq:WP_001295532.1|mint:P0ABG4|dip:DIP-47989N|ensemblbacteria:AAC73200(transcript)|ensemblbacteria:b0089(gene)|ensemblbacteria:BAB96657(gene)|ensemblbacteria:BAB96657(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008955"(peptidoglycan glycosyltransferase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0015648"(lipid-linked peptidoglycan transporter activity)|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|interpro:IPR001182(Cell cycle protein)|interpro:IPR013437(Cell division protein FtsW)|interpro:IPR018365	ensemblbacteria:AAT48132(transcript)|ensemblbacteria:b4409(gene)|ensemblbacteria:BAE76483(gene)|ensemblbacteria:BAE76483(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036460"(cellular response to cell envelope stress)|go:"GO:0046677"(response to antibiotic)|go:"GO:0051301"(cell division)|go:"GO:0000935"(division septum)|refseq:WP_001300888.1|refseq:YP_025303.1	-	-	-	figure legend:Figure 1, 6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2012/11/30	2014/10/16	rogid:gJo0gwDLBv3gJfNlOleO+1ttrWQ83333	rogid:5S1g7w88XVfbrElF7i6T4uBklFc83333	intact-crc:A5CD3FCB9CE164D6|rigid:HmlxmRfmVIgBK+K/2kjiIT6BuvQ	false	-	mutation decreasing interaction strength:12-12	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P06136	uniprotkb:P56976	intact:EBI-1130157|ensemblbacteria:BAB96661|ensemblbacteria:AAC73204	intact:EBI-6419495|ensemblbacteria:AAT48132|ensemblbacteria:BAE76483|uniprotkb:Q2MB73	psi-mi:ftsq_ecoli(display_long)|uniprotkb:ftsQ(gene name)|psi-mi:ftsQ(display_short)|uniprotkb:b0093(locus name)|uniprotkb:JW0091(locus name)	psi-mi:blr_ecoli(display_long)|uniprotkb:blr(gene name)|psi-mi:blr(display_short)|uniprotkb:Beta-lactam resistance protein(gene name synonym)|uniprotkb:JW5963(locus name)|uniprotkb:b4409(locus name)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Karimova et al. (2012)	pubmed:22885295|imex:IM-18476	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6421257|mpidb:MPIDB-INT-1947|imex:IM-18476-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_000075748.1|refseq:NP_414635.1|ensemblbacteria:BAB96661(transcript)|go:"GO:0000917"(division septum assembly)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|ensemblbacteria:BAB96661(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032153"(cell division site)|go:"GO:0042802"(identical protein binding)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|go:"GO:0051301"(cell division)|interpro:IPR005548(Cell division protein FtsQ)|interpro:IPR013685(Polypeptide-transport-associated, FtsQ-type)|interpro:IPR026579|interpro:IPR034746|rcsb pdb:2VH1|rcsb pdb:4UE4|rcsb pdb:4V6M|rcsb pdb:5Z2W|rcsb pdb:6H9N|rcsb pdb:6H9O|ensemblbacteria:AAC73204(transcript)|ensemblbacteria:b0093(gene)|mint:P06136|dip:DIP-9706N	ensemblbacteria:AAT48132(transcript)|ensemblbacteria:b4409(gene)|ensemblbacteria:BAE76483(gene)|ensemblbacteria:BAE76483(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036460"(cellular response to cell envelope stress)|go:"GO:0046677"(response to antibiotic)|go:"GO:0051301"(cell division)|go:"GO:0000935"(division septum)|refseq:WP_001300888.1|refseq:YP_025303.1	-	-	-	figure legend:Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2012/11/30	2014/10/16	rogid:j1yOCAymvXJP5cUtdZYhJilT4iE83333	rogid:5S1g7w88XVfbrElF7i6T4uBklFc83333	intact-crc:DBF30DE9F9F8F4F0|rigid:bnss8O3s9FvWdJaSReQMi+WM3bU	false	-	mutation decreasing interaction strength:12-12	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P76576	uniprotkb:P56976	intact:EBI-907074|uniprotkb:P76982|uniprotkb:P76983|ensemblbacteria:AAC75566|ensemblbacteria:BAA16399	intact:EBI-6419495|ensemblbacteria:AAT48132|ensemblbacteria:BAE76483|uniprotkb:Q2MB73	psi-mi:yfgm_ecoli(display_long)|uniprotkb:yfgM(gene name)|psi-mi:yfgM(display_short)|uniprotkb:Periplasmic chaperone YfgM(gene name synonym)|uniprotkb:JW2497(locus name)|uniprotkb:b2513(locus name)	psi-mi:blr_ecoli(display_long)|uniprotkb:blr(gene name)|psi-mi:blr(display_short)|uniprotkb:Beta-lactam resistance protein(gene name synonym)|uniprotkb:JW5963(locus name)|uniprotkb:b4409(locus name)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Karimova et al. (2012)	pubmed:22885295|imex:IM-18476	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6421254|mpidb:MPIDB-INT-1949|imex:IM-18476-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_417008.1|refseq:WP_000409205.1|dip:DIP-12043N|ensemblbacteria:AAC75566(transcript)|ensemblbacteria:b2513(gene)|ensemblbacteria:BAA16399(gene)|ensemblbacteria:BAA16399(transcript)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0071575"(integral component of external side of plasma membrane)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018704|interpro:IPR026039	ensemblbacteria:AAT48132(transcript)|ensemblbacteria:b4409(gene)|ensemblbacteria:BAE76483(gene)|ensemblbacteria:BAE76483(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036460"(cellular response to cell envelope stress)|go:"GO:0046677"(response to antibiotic)|go:"GO:0051301"(cell division)|go:"GO:0000935"(division septum)|refseq:WP_001300888.1|refseq:YP_025303.1	-	-	-	figure legend:Figure 1, 6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2012/11/30	2014/10/16	rogid:qWAfbMe72X7ULMPuFelLfAkIIoU83333	rogid:5S1g7w88XVfbrElF7i6T4uBklFc83333	intact-crc:5E1B82F09F31E943|rigid:+wwL5xTXVRdu86u/VluRmSyFKZM	false	-	mutation decreasing interaction strength:12-12	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P76576	uniprotkb:P56976	intact:EBI-907074|uniprotkb:P76982|uniprotkb:P76983|ensemblbacteria:AAC75566|ensemblbacteria:BAA16399	intact:EBI-6419495|ensemblbacteria:AAT48132|ensemblbacteria:BAE76483|uniprotkb:Q2MB73	psi-mi:yfgm_ecoli(display_long)|uniprotkb:yfgM(gene name)|psi-mi:yfgM(display_short)|uniprotkb:Periplasmic chaperone YfgM(gene name synonym)|uniprotkb:JW2497(locus name)|uniprotkb:b2513(locus name)	psi-mi:blr_ecoli(display_long)|uniprotkb:blr(gene name)|psi-mi:blr(display_short)|uniprotkb:Beta-lactam resistance protein(gene name synonym)|uniprotkb:JW5963(locus name)|uniprotkb:b4409(locus name)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Karimova et al. (2012)	pubmed:22885295|imex:IM-18476	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6421335|mpidb:MPIDB-INT-1949|imex:IM-18476-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_417008.1|refseq:WP_000409205.1|dip:DIP-12043N|ensemblbacteria:AAC75566(transcript)|ensemblbacteria:b2513(gene)|ensemblbacteria:BAA16399(gene)|ensemblbacteria:BAA16399(transcript)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0071575"(integral component of external side of plasma membrane)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018704|interpro:IPR026039	ensemblbacteria:AAT48132(transcript)|ensemblbacteria:b4409(gene)|ensemblbacteria:BAE76483(gene)|ensemblbacteria:BAE76483(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036460"(cellular response to cell envelope stress)|go:"GO:0046677"(response to antibiotic)|go:"GO:0051301"(cell division)|go:"GO:0000935"(division septum)|refseq:WP_001300888.1|refseq:YP_025303.1	-	-	-	figure legend:Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2012/11/30	2014/10/16	rogid:qWAfbMe72X7ULMPuFelLfAkIIoU83333	rogid:5S1g7w88XVfbrElF7i6T4uBklFc83333	intact-crc:D372C9EEF15590BB|rigid:+wwL5xTXVRdu86u/VluRmSyFKZM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P29131	uniprotkb:P56976	intact:EBI-1134233|uniprotkb:Q2M8M9|ensemblbacteria:AAC76915|ensemblbacteria:BAE77377	intact:EBI-6419495|ensemblbacteria:AAT48132|ensemblbacteria:BAE76483|uniprotkb:Q2MB73	psi-mi:ftsn_ecoli(display_long)|uniprotkb:ftsN(gene name)|psi-mi:ftsN(display_short)|uniprotkb:msgA(gene name synonym)|uniprotkb:b3933(locus name)|uniprotkb:JW3904(locus name)	psi-mi:blr_ecoli(display_long)|uniprotkb:blr(gene name)|psi-mi:blr(display_short)|uniprotkb:Beta-lactam resistance protein(gene name synonym)|uniprotkb:JW5963(locus name)|uniprotkb:b4409(locus name)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Karimova et al. (2012)	pubmed:22885295|imex:IM-18476	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6421380|mpidb:MPIDB-INT-1946|imex:IM-18476-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418368.1|ensemblbacteria:AAC76915(transcript)|ensemblbacteria:b3933(gene)|ensemblbacteria:BAE77377(gene)|ensemblbacteria:BAE77377(transcript)|go:"GO:0000917"(division septum assembly)|go:"GO:0000935"(division septum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0030428"(cell septum)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|go:"GO:0051301"(cell division)|interpro:IPR007730(Sporulation/cell division region, bacteria)|interpro:IPR011930(Cell division protein FtsN)|interpro:IPR036680|rcsb pdb:1UTA|rcsb pdb:6YN0|refseq:WP_000068828.1|mint:P29131|dip:DIP-9705N	ensemblbacteria:AAT48132(transcript)|ensemblbacteria:b4409(gene)|ensemblbacteria:BAE76483(gene)|ensemblbacteria:BAE76483(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036460"(cellular response to cell envelope stress)|go:"GO:0046677"(response to antibiotic)|go:"GO:0051301"(cell division)|go:"GO:0000935"(division septum)|refseq:WP_001300888.1|refseq:YP_025303.1	-	-	-	figure legend:Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2012/11/30	2014/10/16	rogid:tnUJQ/CyPOd0jrCPaBMhjL5saqk83333	rogid:5S1g7w88XVfbrElF7i6T4uBklFc83333	intact-crc:74D802C5402680DA|rigid:HaREKws+54/LrrzTC9506xWGCw4	false	-	mutation with no effect:12-12	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AEN4	uniprotkb:P56976	intact:EBI-1119082|uniprotkb:P22187|uniprotkb:Q8KMX6|ensemblbacteria:AAC73194|ensemblbacteria:BAB96651	intact:EBI-6419495|ensemblbacteria:AAT48132|ensemblbacteria:BAE76483|uniprotkb:Q2MB73	psi-mi:ftsl_ecoli(display_long)|uniprotkb:ftsL(gene name)|psi-mi:ftsL(display_short)|uniprotkb:mraR(gene name synonym)|uniprotkb:b0083(locus name)|uniprotkb:JW0081(locus name)|uniprotkb:yabD(gene name synonym)	psi-mi:blr_ecoli(display_long)|uniprotkb:blr(gene name)|psi-mi:blr(display_short)|uniprotkb:Beta-lactam resistance protein(gene name synonym)|uniprotkb:JW5963(locus name)|uniprotkb:b4409(locus name)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Karimova et al. (2012)	pubmed:22885295|imex:IM-18476	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6421371|mpidb:MPIDB-INT-1943|imex:IM-18476-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAC73194(transcript)|ensemblbacteria:b0083(gene)|ensemblbacteria:BAB96651(gene)|ensemblbacteria:BAB96651(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|interpro:IPR011922(Cell division protein, FtsL -like)|refseq:WP_000625658.1|refseq:NP_414625.1|mint:P0AEN4|dip:DIP-47987N	ensemblbacteria:AAT48132(transcript)|ensemblbacteria:b4409(gene)|ensemblbacteria:BAE76483(gene)|ensemblbacteria:BAE76483(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036460"(cellular response to cell envelope stress)|go:"GO:0046677"(response to antibiotic)|go:"GO:0051301"(cell division)|go:"GO:0000935"(division septum)|refseq:WP_001300888.1|refseq:YP_025303.1	-	-	-	figure legend:Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2012/11/30	2014/10/16	rogid:yDhk71DiRIlAEIv80kZxDalskg483333	rogid:5S1g7w88XVfbrElF7i6T4uBklFc83333	intact-crc:F1379DBC1A38D7EC|rigid:IybcDw4FK0wjHX6WCbikhrfN1pc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P46889	uniprotkb:P56976	intact:EBI-550795|uniprotkb:P77450|ensemblbacteria:AAC73976|ensemblbacteria:BAA35615	intact:EBI-6419495|ensemblbacteria:AAT48132|ensemblbacteria:BAE76483|uniprotkb:Q2MB73	psi-mi:ftsk_ecoli(display_long)|uniprotkb:ftsK(gene name)|psi-mi:ftsK(display_short)|uniprotkb:b0890(locus name)|uniprotkb:JW0873(locus name)	psi-mi:blr_ecoli(display_long)|uniprotkb:blr(gene name)|psi-mi:blr(display_short)|uniprotkb:Beta-lactam resistance protein(gene name synonym)|uniprotkb:JW5963(locus name)|uniprotkb:b4409(locus name)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Karimova et al. (2012)	pubmed:22885295|imex:IM-18476	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6421355|mpidb:MPIDB-INT-1945|imex:IM-18476-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415410.1|refseq:WP_000076967.1|dip:DIP-9703N|ensemblbacteria:AAC73976(transcript)|ensemblbacteria:b0890(gene)|ensemblbacteria:BAA35615(gene)|ensemblbacteria:BAA35615(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009651"(response to salt stress)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016020"(membrane)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0071236"(cellular response to antibiotic)|interpro:IPR002543(Cell divisionFtsK/SpoIIIE)|interpro:IPR018541|interpro:IPR025199|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|interpro:IPR041027|rcsb pdb:2IUS|rcsb pdb:2J5P|rcsb pdb:5DCF	ensemblbacteria:AAT48132(transcript)|ensemblbacteria:b4409(gene)|ensemblbacteria:BAE76483(gene)|ensemblbacteria:BAE76483(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036460"(cellular response to cell envelope stress)|go:"GO:0046677"(response to antibiotic)|go:"GO:0051301"(cell division)|go:"GO:0000935"(division septum)|refseq:WP_001300888.1|refseq:YP_025303.1	-	-	-	figure legend:Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2012/11/30	2014/10/16	rogid:Y1xWjJKAumQKFqgg6IAFaRIxJXg83333	rogid:5S1g7w88XVfbrElF7i6T4uBklFc83333	intact-crc:0F2A9A7935604E27|rigid:XIZq/rsg8v70H31hEQbfD9L6MGM	false	sufficient binding region:1-271	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P46889	uniprotkb:P56976	intact:EBI-550795|uniprotkb:P77450|ensemblbacteria:AAC73976|ensemblbacteria:BAA35615	intact:EBI-6419495|ensemblbacteria:AAT48132|ensemblbacteria:BAE76483|uniprotkb:Q2MB73	psi-mi:ftsk_ecoli(display_long)|uniprotkb:ftsK(gene name)|psi-mi:ftsK(display_short)|uniprotkb:b0890(locus name)|uniprotkb:JW0873(locus name)	psi-mi:blr_ecoli(display_long)|uniprotkb:blr(gene name)|psi-mi:blr(display_short)|uniprotkb:Beta-lactam resistance protein(gene name synonym)|uniprotkb:JW5963(locus name)|uniprotkb:b4409(locus name)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Karimova et al. (2012)	pubmed:22885295|imex:IM-18476	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6421242|mpidb:MPIDB-INT-1945|imex:IM-18476-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_415410.1|refseq:WP_000076967.1|dip:DIP-9703N|ensemblbacteria:AAC73976(transcript)|ensemblbacteria:b0890(gene)|ensemblbacteria:BAA35615(gene)|ensemblbacteria:BAA35615(transcript)|go:"GO:0000920"(septum digestion after cytokinesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009651"(response to salt stress)|go:"GO:0015616"(DNA translocase activity)|go:"GO:0016020"(membrane)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:0071236"(cellular response to antibiotic)|interpro:IPR002543(Cell divisionFtsK/SpoIIIE)|interpro:IPR018541|interpro:IPR025199|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|interpro:IPR041027|rcsb pdb:2IUS|rcsb pdb:2J5P|rcsb pdb:5DCF	ensemblbacteria:AAT48132(transcript)|ensemblbacteria:b4409(gene)|ensemblbacteria:BAE76483(gene)|ensemblbacteria:BAE76483(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036460"(cellular response to cell envelope stress)|go:"GO:0046677"(response to antibiotic)|go:"GO:0051301"(cell division)|go:"GO:0000935"(division septum)|refseq:WP_001300888.1|refseq:YP_025303.1	-	-	-	figure legend:Figure 1, 6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2012/11/30	2014/10/16	rogid:Y1xWjJKAumQKFqgg6IAFaRIxJXg83333	rogid:5S1g7w88XVfbrElF7i6T4uBklFc83333	intact-crc:1B0756559FBFB083|rigid:XIZq/rsg8v70H31hEQbfD9L6MGM	false	sufficient binding region:1-271	mutation decreasing interaction strength:12-12	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P29131	uniprotkb:P56976	intact:EBI-1134233|uniprotkb:Q2M8M9|ensemblbacteria:AAC76915|ensemblbacteria:BAE77377	intact:EBI-6419495|ensemblbacteria:AAT48132|ensemblbacteria:BAE76483|uniprotkb:Q2MB73	psi-mi:ftsn_ecoli(display_long)|uniprotkb:ftsN(gene name)|psi-mi:ftsN(display_short)|uniprotkb:msgA(gene name synonym)|uniprotkb:b3933(locus name)|uniprotkb:JW3904(locus name)	psi-mi:blr_ecoli(display_long)|uniprotkb:blr(gene name)|psi-mi:blr(display_short)|uniprotkb:Beta-lactam resistance protein(gene name synonym)|uniprotkb:JW5963(locus name)|uniprotkb:b4409(locus name)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Karimova et al. (2012)	pubmed:22885295|imex:IM-18476	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6421345|imex:IM-18476-15|mpidb:MPIDB-INT-1946	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418368.1|ensemblbacteria:AAC76915(transcript)|ensemblbacteria:b3933(gene)|ensemblbacteria:BAE77377(gene)|ensemblbacteria:BAE77377(transcript)|go:"GO:0000917"(division septum assembly)|go:"GO:0000935"(division septum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0030428"(cell septum)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|go:"GO:0051301"(cell division)|interpro:IPR007730(Sporulation/cell division region, bacteria)|interpro:IPR011930(Cell division protein FtsN)|interpro:IPR036680|rcsb pdb:1UTA|rcsb pdb:6YN0|refseq:WP_000068828.1|mint:P29131|dip:DIP-9705N	ensemblbacteria:AAT48132(transcript)|ensemblbacteria:b4409(gene)|ensemblbacteria:BAE76483(gene)|ensemblbacteria:BAE76483(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036460"(cellular response to cell envelope stress)|go:"GO:0046677"(response to antibiotic)|go:"GO:0051301"(cell division)|go:"GO:0000935"(division septum)|refseq:WP_001300888.1|refseq:YP_025303.1	-	-	-	figure legend:Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2012/11/30	2014/10/16	rogid:tnUJQ/CyPOd0jrCPaBMhjL5saqk83333	rogid:5S1g7w88XVfbrElF7i6T4uBklFc83333	intact-crc:372EA6B20A8823BF|rigid:HaREKws+54/LrrzTC9506xWGCw4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AD68	uniprotkb:P56976	intact:EBI-548564|uniprotkb:P04286|ensemblbacteria:BAB96652|ensemblbacteria:AAC73195	intact:EBI-6419495|ensemblbacteria:AAT48132|ensemblbacteria:BAE76483|uniprotkb:Q2MB73	psi-mi:ftsi_ecoli(display_long)|uniprotkb:ftsI(gene name)|psi-mi:ftsI(display_short)|uniprotkb:pbpB(gene name synonym)|uniprotkb:b0084(locus name)|uniprotkb:Penicillin-binding protein 3(gene name synonym)|uniprotkb:JW0082(locus name)|uniprotkb:Essential cell division protein FtsI(gene name synonym)|uniprotkb:Murein transpeptidase(gene name synonym)|uniprotkb:Peptidoglycan synthase FtsI(gene name synonym)	psi-mi:blr_ecoli(display_long)|uniprotkb:blr(gene name)|psi-mi:blr(display_short)|uniprotkb:Beta-lactam resistance protein(gene name synonym)|uniprotkb:JW5963(locus name)|uniprotkb:b4409(locus name)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Karimova et al. (2012)	pubmed:22885295|imex:IM-18476	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6421364|mpidb:MPIDB-INT-1944|imex:IM-18476-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_414626.1|refseq:WP_000642196.1|mint:P0AD68|dip:DIP-47950N|rcsb pdb:6HZQ|ensemblbacteria:AAC73195(transcript)|ensemblbacteria:b0084(gene)|ensemblbacteria:BAB96652(gene)|ensemblbacteria:BAB96652(transcript)|go:"GO:0000917"(division septum assembly)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008658"(penicillin binding)|go:"GO:0008955"(peptidoglycan glycosyltransferase activity)|go:"GO:0009002"(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0032153"(cell division site)|go:"GO:0042493"|go:"GO:0043093"(FtsZ-dependent cytokinesis)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|interpro:IPR001460(Penicillin-binding protein, transpeptidase)|interpro:IPR005311(Penicillin-binding protein, dimerisation domain)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR036138|interpro:IPR037532	ensemblbacteria:AAT48132(transcript)|ensemblbacteria:b4409(gene)|ensemblbacteria:BAE76483(gene)|ensemblbacteria:BAE76483(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036460"(cellular response to cell envelope stress)|go:"GO:0046677"(response to antibiotic)|go:"GO:0051301"(cell division)|go:"GO:0000935"(division septum)|refseq:WP_001300888.1|refseq:YP_025303.1	-	caution:This sequence has been withdrawn from Uniprot.	-	figure legend:Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2012/11/30	2014/10/16	rogid:t2/vZi0YAamNjApJJn0qtB6NQLM83333	rogid:5S1g7w88XVfbrElF7i6T4uBklFc83333	intact-crc:1423CE3C00FE7F8F|rigid:GSIqPsINb1NyFF1OfEIaeBvAPt8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AD68	uniprotkb:P56976	intact:EBI-548564|uniprotkb:P04286|ensemblbacteria:BAB96652|ensemblbacteria:AAC73195	intact:EBI-6419495|ensemblbacteria:AAT48132|ensemblbacteria:BAE76483|uniprotkb:Q2MB73	psi-mi:ftsi_ecoli(display_long)|uniprotkb:ftsI(gene name)|psi-mi:ftsI(display_short)|uniprotkb:pbpB(gene name synonym)|uniprotkb:b0084(locus name)|uniprotkb:Penicillin-binding protein 3(gene name synonym)|uniprotkb:JW0082(locus name)|uniprotkb:Essential cell division protein FtsI(gene name synonym)|uniprotkb:Murein transpeptidase(gene name synonym)|uniprotkb:Peptidoglycan synthase FtsI(gene name synonym)	psi-mi:blr_ecoli(display_long)|uniprotkb:blr(gene name)|psi-mi:blr(display_short)|uniprotkb:Beta-lactam resistance protein(gene name synonym)|uniprotkb:JW5963(locus name)|uniprotkb:b4409(locus name)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Karimova et al. (2012)	pubmed:22885295|imex:IM-18476	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6421248|mpidb:MPIDB-INT-1944|imex:IM-18476-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_414626.1|refseq:WP_000642196.1|mint:P0AD68|dip:DIP-47950N|rcsb pdb:6HZQ|ensemblbacteria:AAC73195(transcript)|ensemblbacteria:b0084(gene)|ensemblbacteria:BAB96652(gene)|ensemblbacteria:BAB96652(transcript)|go:"GO:0000917"(division septum assembly)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008658"(penicillin binding)|go:"GO:0008955"(peptidoglycan glycosyltransferase activity)|go:"GO:0009002"(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0032153"(cell division site)|go:"GO:0042493"|go:"GO:0043093"(FtsZ-dependent cytokinesis)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|interpro:IPR001460(Penicillin-binding protein, transpeptidase)|interpro:IPR005311(Penicillin-binding protein, dimerisation domain)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR036138|interpro:IPR037532	ensemblbacteria:AAT48132(transcript)|ensemblbacteria:b4409(gene)|ensemblbacteria:BAE76483(gene)|ensemblbacteria:BAE76483(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036460"(cellular response to cell envelope stress)|go:"GO:0046677"(response to antibiotic)|go:"GO:0051301"(cell division)|go:"GO:0000935"(division septum)|refseq:WP_001300888.1|refseq:YP_025303.1	-	caution:This sequence has been withdrawn from Uniprot.	-	figure legend:Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2012/11/30	2014/10/16	rogid:t2/vZi0YAamNjApJJn0qtB6NQLM83333	rogid:5S1g7w88XVfbrElF7i6T4uBklFc83333	intact-crc:6D8FD9AB03697237|rigid:GSIqPsINb1NyFF1OfEIaeBvAPt8	false	-	mutation decreasing interaction strength:12-12	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AEN4	uniprotkb:P56976	intact:EBI-1119082|uniprotkb:P22187|uniprotkb:Q8KMX6|ensemblbacteria:AAC73194|ensemblbacteria:BAB96651	intact:EBI-6419495|ensemblbacteria:AAT48132|ensemblbacteria:BAE76483|uniprotkb:Q2MB73	psi-mi:ftsl_ecoli(display_long)|uniprotkb:ftsL(gene name)|psi-mi:ftsL(display_short)|uniprotkb:mraR(gene name synonym)|uniprotkb:b0083(locus name)|uniprotkb:JW0081(locus name)|uniprotkb:yabD(gene name synonym)	psi-mi:blr_ecoli(display_long)|uniprotkb:blr(gene name)|psi-mi:blr(display_short)|uniprotkb:Beta-lactam resistance protein(gene name synonym)|uniprotkb:JW5963(locus name)|uniprotkb:b4409(locus name)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Karimova et al. (2012)	pubmed:22885295|imex:IM-18476	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6421260|mpidb:MPIDB-INT-1943|imex:IM-18476-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAC73194(transcript)|ensemblbacteria:b0083(gene)|ensemblbacteria:BAB96651(gene)|ensemblbacteria:BAB96651(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|interpro:IPR011922(Cell division protein, FtsL -like)|refseq:WP_000625658.1|refseq:NP_414625.1|mint:P0AEN4|dip:DIP-47987N	ensemblbacteria:AAT48132(transcript)|ensemblbacteria:b4409(gene)|ensemblbacteria:BAE76483(gene)|ensemblbacteria:BAE76483(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036460"(cellular response to cell envelope stress)|go:"GO:0046677"(response to antibiotic)|go:"GO:0051301"(cell division)|go:"GO:0000935"(division septum)|refseq:WP_001300888.1|refseq:YP_025303.1	-	-	-	figure legend:Figure 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2012/11/30	2014/10/16	rogid:yDhk71DiRIlAEIv80kZxDalskg483333	rogid:5S1g7w88XVfbrElF7i6T4uBklFc83333	intact-crc:F1E51C1DC955D6EE|rigid:IybcDw4FK0wjHX6WCbikhrfN1pc	false	-	mutation decreasing interaction:12-12	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P29131	uniprotkb:P56976	intact:EBI-1134233|uniprotkb:Q2M8M9|ensemblbacteria:AAC76915|ensemblbacteria:BAE77377	intact:EBI-6419495|ensemblbacteria:AAT48132|ensemblbacteria:BAE76483|uniprotkb:Q2MB73	psi-mi:ftsn_ecoli(display_long)|uniprotkb:ftsN(gene name)|psi-mi:ftsN(display_short)|uniprotkb:msgA(gene name synonym)|uniprotkb:b3933(locus name)|uniprotkb:JW3904(locus name)	psi-mi:blr_ecoli(display_long)|uniprotkb:blr(gene name)|psi-mi:blr(display_short)|uniprotkb:Beta-lactam resistance protein(gene name synonym)|uniprotkb:JW5963(locus name)|uniprotkb:b4409(locus name)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Karimova et al. (2012)	pubmed:22885295|imex:IM-18476	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6421236|mpidb:MPIDB-INT-1946|imex:IM-18476-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_418368.1|ensemblbacteria:AAC76915(transcript)|ensemblbacteria:b3933(gene)|ensemblbacteria:BAE77377(gene)|ensemblbacteria:BAE77377(transcript)|go:"GO:0000917"(division septum assembly)|go:"GO:0000935"(division septum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0030428"(cell septum)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|go:"GO:0051301"(cell division)|interpro:IPR007730(Sporulation/cell division region, bacteria)|interpro:IPR011930(Cell division protein FtsN)|interpro:IPR036680|rcsb pdb:1UTA|rcsb pdb:6YN0|refseq:WP_000068828.1|mint:P29131|dip:DIP-9705N	ensemblbacteria:AAT48132(transcript)|ensemblbacteria:b4409(gene)|ensemblbacteria:BAE76483(gene)|ensemblbacteria:BAE76483(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036460"(cellular response to cell envelope stress)|go:"GO:0046677"(response to antibiotic)|go:"GO:0051301"(cell division)|go:"GO:0000935"(division septum)|refseq:WP_001300888.1|refseq:YP_025303.1	-	-	-	figure legend:Figure 1, 6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2012/11/30	2014/10/16	rogid:tnUJQ/CyPOd0jrCPaBMhjL5saqk83333	rogid:5S1g7w88XVfbrElF7i6T4uBklFc83333	intact-crc:8C5D8EB08E91E06D|rigid:HaREKws+54/LrrzTC9506xWGCw4	false	-	mutation decreasing interaction:12-12	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0AFX7	uniprotkb:P0AEN4	intact:EBI-1117560|uniprotkb:P38106|uniprotkb:Q2MAF8|ensemblbacteria:AAC75625|ensemblbacteria:BAE76748	intact:EBI-1119082|uniprotkb:P22187|uniprotkb:Q8KMX6|ensemblbacteria:AAC73194|ensemblbacteria:BAB96651	psi-mi:rsea_ecoli(display_long)|uniprotkb:yfiJ(gene name synonym)|uniprotkb:rseA(gene name)|psi-mi:rseA(display_short)|uniprotkb:mclA(gene name synonym)|uniprotkb:b2572(locus name)|uniprotkb:JW2556(locus name)|uniprotkb:Regulator of SigE(gene name synonym)|uniprotkb:Sigma-E anti-sigma factor RseA(gene name synonym)|uniprotkb:Sigma-E factor negative regulatory protein(gene name synonym)	psi-mi:ftsl_ecoli(display_long)|uniprotkb:ftsL(gene name)|psi-mi:ftsL(display_short)|uniprotkb:mraR(gene name synonym)|uniprotkb:b0083(locus name)|uniprotkb:JW0081(locus name)|uniprotkb:yabD(gene name synonym)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Karimova et al. (2012)	pubmed:22885295|imex:IM-18476	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6419479|mpidb:MPIDB-INT-1941|imex:IM-18476-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_417067.1|ensemblbacteria:AAC75625(transcript)|ensemblbacteria:b2572(gene)|ensemblbacteria:BAE76748(gene)|ensemblbacteria:BAE76748(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016989"(sigma factor antagonist activity)|interpro:IPR005572(Anti sigma-E protein RseA, N-terminal)|interpro:IPR005573(Anti sigma-E protein RseA, C-terminal)|interpro:IPR026279|interpro:IPR036147|rcsb pdb:1OR7|rcsb pdb:1YFN|rcsb pdb:3M4W|refseq:WP_001168459.1|dip:DIP-39581N	ensemblbacteria:AAC73194(transcript)|ensemblbacteria:b0083(gene)|ensemblbacteria:BAB96651(gene)|ensemblbacteria:BAB96651(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|interpro:IPR011922(Cell division protein, FtsL -like)|refseq:WP_000625658.1|refseq:NP_414625.1|mint:P0AEN4|dip:DIP-47987N	-	-	-	figure legend:Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2012/11/30	2014/10/16	rogid:tpuDQBjnIhDZEQzGSs4rw3+LLcg83333	rogid:yDhk71DiRIlAEIv80kZxDalskg483333	intact-crc:DBF26F9BCB95EE64|rigid:EMqAoz3FV0D05qQ6ml12VT9ZBLo	false	sufficient binding region:68-216	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0AEN4	uniprotkb:P76576	intact:EBI-1119082|uniprotkb:P22187|uniprotkb:Q8KMX6|ensemblbacteria:AAC73194|ensemblbacteria:BAB96651	intact:EBI-907074|uniprotkb:P76982|uniprotkb:P76983|ensemblbacteria:AAC75566|ensemblbacteria:BAA16399	psi-mi:ftsl_ecoli(display_long)|uniprotkb:ftsL(gene name)|psi-mi:ftsL(display_short)|uniprotkb:mraR(gene name synonym)|uniprotkb:b0083(locus name)|uniprotkb:JW0081(locus name)|uniprotkb:yabD(gene name synonym)	psi-mi:yfgm_ecoli(display_long)|uniprotkb:yfgM(gene name)|psi-mi:yfgM(display_short)|uniprotkb:Periplasmic chaperone YfgM(gene name synonym)|uniprotkb:JW2497(locus name)|uniprotkb:b2513(locus name)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Karimova et al. (2012)	pubmed:22885295|imex:IM-18476	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6419487|mpidb:MPIDB-INT-1940|imex:IM-18476-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAC73194(transcript)|ensemblbacteria:b0083(gene)|ensemblbacteria:BAB96651(gene)|ensemblbacteria:BAB96651(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|interpro:IPR011922(Cell division protein, FtsL -like)|refseq:WP_000625658.1|refseq:NP_414625.1|mint:P0AEN4|dip:DIP-47987N	refseq:NP_417008.1|refseq:WP_000409205.1|dip:DIP-12043N|ensemblbacteria:AAC75566(transcript)|ensemblbacteria:b2513(gene)|ensemblbacteria:BAA16399(gene)|ensemblbacteria:BAA16399(transcript)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0071575"(integral component of external side of plasma membrane)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018704|interpro:IPR026039	-	-	-	figure legend:Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2012/11/30	2014/10/16	rogid:yDhk71DiRIlAEIv80kZxDalskg483333	rogid:qWAfbMe72X7ULMPuFelLfAkIIoU83333	intact-crc:EB5418E2DCBD741B|rigid:Xmox0jAJAGPzLA1LsX6DDDPZD4M	false	-	sufficient binding region:17-72	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P15286	uniprotkb:P0AEN4	intact:EBI-1128437|uniprotkb:P77706|uniprotkb:Q9JN62|ensemblbacteria:AAC75381|ensemblbacteria:BAA16178	intact:EBI-1119082|uniprotkb:P22187|uniprotkb:Q8KMX6|ensemblbacteria:AAC73194|ensemblbacteria:BAB96651	psi-mi:flk_ecoli(display_long)|uniprotkb:flk(gene name)|psi-mi:flk(display_short)|uniprotkb:b2321(locus name)|uniprotkb:JW2318(locus name)|uniprotkb:div(gene name synonym)|uniprotkb:Fluke(gene name synonym)	psi-mi:ftsl_ecoli(display_long)|uniprotkb:ftsL(gene name)|psi-mi:ftsL(display_short)|uniprotkb:mraR(gene name synonym)|uniprotkb:b0083(locus name)|uniprotkb:JW0081(locus name)|uniprotkb:yabD(gene name synonym)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Karimova et al. (2012)	pubmed:22885295|imex:IM-18476	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6419471|mpidb:MPIDB-INT-1942|imex:IM-18476-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_416824.1|refseq:WP_000615834.1|ensemblbacteria:AAC75381(transcript)|ensemblbacteria:b2321(gene)|ensemblbacteria:BAA16178(gene)|ensemblbacteria:BAA16178(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|interpro:IPR023597|dip:DIP-9448N	ensemblbacteria:AAC73194(transcript)|ensemblbacteria:b0083(gene)|ensemblbacteria:BAB96651(gene)|ensemblbacteria:BAB96651(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|interpro:IPR011922(Cell division protein, FtsL -like)|refseq:WP_000625658.1|refseq:NP_414625.1|mint:P0AEN4|dip:DIP-47987N	-	-	-	figure legend:Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2012/11/30	2014/10/16	rogid:GY8uR6wia1LwjP/ng75WXRtx0vM83333	rogid:yDhk71DiRIlAEIv80kZxDalskg483333	intact-crc:6C68524A1F3D41EF|rigid:+X+gYier5deXwccQv3PO1wL2tzY	false	sufficient binding region:114-331	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0AD68	uniprotkb:P0AEN4	intact:EBI-548564|uniprotkb:P04286|ensemblbacteria:BAB96652|ensemblbacteria:AAC73195	intact:EBI-1119082|uniprotkb:P22187|uniprotkb:Q8KMX6|ensemblbacteria:AAC73194|ensemblbacteria:BAB96651	psi-mi:ftsi_ecoli(display_long)|uniprotkb:ftsI(gene name)|psi-mi:ftsI(display_short)|uniprotkb:pbpB(gene name synonym)|uniprotkb:b0084(locus name)|uniprotkb:Penicillin-binding protein 3(gene name synonym)|uniprotkb:JW0082(locus name)|uniprotkb:Essential cell division protein FtsI(gene name synonym)|uniprotkb:Murein transpeptidase(gene name synonym)|uniprotkb:Peptidoglycan synthase FtsI(gene name synonym)	psi-mi:ftsl_ecoli(display_long)|uniprotkb:ftsL(gene name)|psi-mi:ftsL(display_short)|uniprotkb:mraR(gene name synonym)|uniprotkb:b0083(locus name)|uniprotkb:JW0081(locus name)|uniprotkb:yabD(gene name synonym)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Karimova et al. (2012)	pubmed:22885295|imex:IM-18476	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6419511|mpidb:MPIDB-INT-1938|imex:IM-18476-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_414626.1|refseq:WP_000642196.1|mint:P0AD68|dip:DIP-47950N|rcsb pdb:6HZQ|ensemblbacteria:AAC73195(transcript)|ensemblbacteria:b0084(gene)|ensemblbacteria:BAB96652(gene)|ensemblbacteria:BAB96652(transcript)|go:"GO:0000917"(division septum assembly)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008658"(penicillin binding)|go:"GO:0008955"(peptidoglycan glycosyltransferase activity)|go:"GO:0009002"(serine-type D-Ala-D-Ala carboxypeptidase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0032153"(cell division site)|go:"GO:0042493"|go:"GO:0043093"(FtsZ-dependent cytokinesis)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|interpro:IPR001460(Penicillin-binding protein, transpeptidase)|interpro:IPR005311(Penicillin-binding protein, dimerisation domain)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR036138|interpro:IPR037532	ensemblbacteria:AAC73194(transcript)|ensemblbacteria:b0083(gene)|ensemblbacteria:BAB96651(gene)|ensemblbacteria:BAB96651(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|interpro:IPR011922(Cell division protein, FtsL -like)|refseq:WP_000625658.1|refseq:NP_414625.1|mint:P0AEN4|dip:DIP-47987N	-	caution:This sequence has been withdrawn from Uniprot.	-	figure legend:Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2012/11/30	2014/10/16	rogid:t2/vZi0YAamNjApJJn0qtB6NQLM83333	rogid:yDhk71DiRIlAEIv80kZxDalskg483333	intact-crc:A68995295385B83C|rigid:YGqMPpFi0Iq+RhG0rV2UabxZJAg	false	sufficient binding region:9-193	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0ABG4	uniprotkb:P0AEN4	intact:EBI-1214767|uniprotkb:P16457|ensemblbacteria:AAC73200|ensemblbacteria:BAB96657	intact:EBI-1119082|uniprotkb:P22187|uniprotkb:Q8KMX6|ensemblbacteria:AAC73194|ensemblbacteria:BAB96651	psi-mi:ftsw_ecoli(display_long)|uniprotkb:ftsW(gene name)|psi-mi:ftsW(display_short)|uniprotkb:Cell division protein FtsW(gene name synonym)|uniprotkb:Cell wall polymerase(gene name synonym)|uniprotkb:Lipid II flippase FtsW(gene name synonym)|uniprotkb:Peptidoglycan polymerase(gene name synonym)|uniprotkb:JW0087(locus name)|uniprotkb:b0089(locus name)	psi-mi:ftsl_ecoli(display_long)|uniprotkb:ftsL(gene name)|psi-mi:ftsL(display_short)|uniprotkb:mraR(gene name synonym)|uniprotkb:b0083(locus name)|uniprotkb:JW0081(locus name)|uniprotkb:yabD(gene name synonym)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Karimova et al. (2012)	pubmed:22885295|imex:IM-18476	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6419519|mpidb:MPIDB-INT-1937|imex:IM-18476-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_414631.1|refseq:WP_001295532.1|mint:P0ABG4|dip:DIP-47989N|ensemblbacteria:AAC73200(transcript)|ensemblbacteria:b0089(gene)|ensemblbacteria:BAB96657(gene)|ensemblbacteria:BAB96657(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008955"(peptidoglycan glycosyltransferase activity)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0015648"(lipid-linked peptidoglycan transporter activity)|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|go:"GO:0051301"(cell division)|go:"GO:0071555"(cell wall organization)|interpro:IPR001182(Cell cycle protein)|interpro:IPR013437(Cell division protein FtsW)|interpro:IPR018365	ensemblbacteria:AAC73194(transcript)|ensemblbacteria:b0083(gene)|ensemblbacteria:BAB96651(gene)|ensemblbacteria:BAB96651(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|interpro:IPR011922(Cell division protein, FtsL -like)|refseq:WP_000625658.1|refseq:NP_414625.1|mint:P0AEN4|dip:DIP-47987N	-	-	-	figure legend:Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2012/11/30	2014/10/16	rogid:gJo0gwDLBv3gJfNlOleO+1ttrWQ83333	rogid:yDhk71DiRIlAEIv80kZxDalskg483333	intact-crc:FDD8CF76B8E219A3|rigid:a5y9b0z0gqNBQu8ms3PjETKorlY	false	sufficient binding region:23-213	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P0AEN4	uniprotkb:P56976	intact:EBI-1119082|uniprotkb:P22187|uniprotkb:Q8KMX6|ensemblbacteria:AAC73194|ensemblbacteria:BAB96651	intact:EBI-6419495|ensemblbacteria:AAT48132|ensemblbacteria:BAE76483|uniprotkb:Q2MB73	psi-mi:ftsl_ecoli(display_long)|uniprotkb:ftsL(gene name)|psi-mi:ftsL(display_short)|uniprotkb:mraR(gene name synonym)|uniprotkb:b0083(locus name)|uniprotkb:JW0081(locus name)|uniprotkb:yabD(gene name synonym)	psi-mi:blr_ecoli(display_long)|uniprotkb:blr(gene name)|psi-mi:blr(display_short)|uniprotkb:Beta-lactam resistance protein(gene name synonym)|uniprotkb:JW5963(locus name)|uniprotkb:b4409(locus name)	psi-mi:"MI:0014"(adenylate cyclase complementation)	Karimova et al. (2012)	pubmed:22885295|imex:IM-18476	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0903"(mpidb)	intact:EBI-6419503|mpidb:MPIDB-INT-1939|imex:IM-18476-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblbacteria:AAC73194(transcript)|ensemblbacteria:b0083(gene)|ensemblbacteria:BAB96651(gene)|ensemblbacteria:BAB96651(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|interpro:IPR011922(Cell division protein, FtsL -like)|refseq:WP_000625658.1|refseq:NP_414625.1|mint:P0AEN4|dip:DIP-47987N	ensemblbacteria:AAT48132(transcript)|ensemblbacteria:b4409(gene)|ensemblbacteria:BAE76483(gene)|ensemblbacteria:BAE76483(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036460"(cellular response to cell envelope stress)|go:"GO:0046677"(response to antibiotic)|go:"GO:0051301"(cell division)|go:"GO:0000935"(division septum)|refseq:WP_001300888.1|refseq:YP_025303.1	-	-	-	figure legend:Table 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2012/11/30	2014/10/16	rogid:yDhk71DiRIlAEIv80kZxDalskg483333	rogid:5S1g7w88XVfbrElF7i6T4uBklFc83333	intact-crc:9E8818918748A53E|rigid:IybcDw4FK0wjHX6WCbikhrfN1pc	false	-	sufficient binding region:3-41	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)