#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9Z108 uniprotkb:P04756 intact:EBI-8020609|intact:UNK-5561237|ensembl:ENSMUSP00000104859 intact:EBI-8020577|intact:MINT-8388618|ensembl:ENSMUSP00000028515 psi-mi:stau1_mouse(display_long)|uniprotkb:Stau1(gene name)|psi-mi:Stau1(display_short)|uniprotkb:Stau(gene name synonym) psi-mi:acha_mouse(display_long)|uniprotkb:Chrna1(gene name)|psi-mi:Chrna1(display_short)|uniprotkb:Acra(gene name synonym) psi-mi:"MI:0096"(pull down) Chang et al. (2012) pubmed:22884571|mint:MINT-8388613 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8020572|mint:MINT-8388648 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035620.1|ensembl:ENSMUSG00000039536(gene)|ensembl:ENSMUST00000109236(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030425"(dendrite)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:Q9Z108|mint:MINT-8388651(identity) refseq:NP_031415.2|dip:DIP-59594N|ensembl:ENSMUSG00000027107(gene)|ensembl:ENSMUST00000028515(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005892"(acetylcholine-gated channel complex)|go:"GO:0006812"(cation transport)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007271"(synaptic transmission, cholinergic)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0022848"(acetylcholine-gated cation-selective channel activity)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048630"(skeletal muscle tissue growth)|go:"GO:0050877"(nervous system process)|go:"GO:0050881"(musculoskeletal movement)|go:"GO:0050905"(neuromuscular process)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR002394(Nicotinic acetylcholine receptor, N-terminal)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|rcsb pdb:2QC1|rcsb pdb:5HBV|reactome:R-MMU-629594|reactome:R-MMU-629597|mint:MINT-8388650(identity) - comment:mint|function:"Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site" comment:mint figure legend:f4b|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/07/23 2014/10/16 rogid:9zPJq1T9MxPD12EiZZWLuRcCpTk10090 rogid:msAV7/sGGuVPx3JlcwHr2qXnvTE10090 intact-crc:D1D3FDF22ED8A6AC|rigid:qtWj0SZ5tWQZEpvVAPfNPPzaPl0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P60615 uniprotkb:Q9Z108 intact:EBI-7516391|uniprotkb:Q9PRI6|uniprotkb:Q9YI07|uniprotkb:P01378|uniprotkb:Q9YGD1|uniprotkb:Q9YI11|uniprotkb:Q9YI06|intact:MINT-5223718|uniprotkb:Q9YI09|uniprotkb:Q9YI10|uniprotkb:Q9YI13|uniprotkb:Q9YI12 intact:EBI-8020609|intact:UNK-5561237|ensembl:ENSMUSP00000104859 psi-mi:3l21a_bunmu(display_long)|uniprotkb:Long neurotoxin 1(gene name synonym)|uniprotkb:Alpha-bungarotoxin, isoform A31(gene name synonym)|uniprotkb:Alpha-elapitoxin-Bm2a(gene name synonym) psi-mi:stau1_mouse(display_long)|uniprotkb:Stau1(gene name)|psi-mi:Stau1(display_short)|uniprotkb:Stau(gene name synonym) psi-mi:"MI:0096"(pull down) Chang et al. (2012) pubmed:22884571|mint:MINT-8388613 taxid:8616(bunmu)|taxid:8616(Bungarus multicinctus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8020653|mint:MINT-8389602 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P60615|interpro:IPR035076|interpro:IPR018354|interpro:IPR003571(Snake toxin)|go:"GO:0005576"(extracellular region)|go:"GO:0090729"(toxin activity)|rcsb pdb:1ABT|rcsb pdb:1BXP|rcsb pdb:1HAA|rcsb pdb:1HAJ|rcsb pdb:1HC9|rcsb pdb:1HOY|rcsb pdb:1IDG|rcsb pdb:1IDH|rcsb pdb:1IDI|rcsb pdb:1IDL|rcsb pdb:1IK8|rcsb pdb:1IKC|rcsb pdb:1JBD|rcsb pdb:1KC4|rcsb pdb:1KFH|rcsb pdb:1KL8|rcsb pdb:1L4W|rcsb pdb:1LJZ|rcsb pdb:1LK1|rcsb pdb:1RGJ|rcsb pdb:2ABX|rcsb pdb:2BTX|rcsb pdb:6UWZ|mint:MINT-8389604(identity) refseq:NP_035620.1|ensembl:ENSMUSG00000039536(gene)|ensembl:ENSMUST00000109236(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030425"(dendrite)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:Q9Z108|mint:MINT-8389606(identity) - comment:mint|function:"Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site. Binds to muscular and neuronal (alpha-7, alpha-8, and alpha-9) nicotinic acetylcholine receptors. Blocks the extracellular increase of dopamine evoked by nicotine only at the higher dose (4.2 uM)" comment:mint|function:"Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site" figure legend:f4b|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/07/23 2014/10/16 rogid:H8HmrCO0Ummh3xuVj5FOUmoCcN08616 rogid:9zPJq1T9MxPD12EiZZWLuRcCpTk10090 intact-crc:6A639AC888B7925E|rigid:CQoQjEjtwLCm+VyNpkIrHkY0qt4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot)