#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q53HC0	uniprotkb:Q9UPV0	intact:EBI-719994|uniprotkb:Q9H697|uniprotkb:B3KNQ0|ensembl:ENSP00000238156|ensembl:ENSP00000488830	intact:EBI-3937015|uniprotkb:Q9UFJ6|uniprotkb:Q9NVS0|uniprotkb:Q6PKH9|uniprotkb:Q7Z2X9|ensembl:ENSP00000278935	psi-mi:ccd92_human(display_long)|uniprotkb:Limkain beta-2(gene name synonym)|uniprotkb:CCDC92(gene name)|psi-mi:CCDC92(display_short)	psi-mi:ce164_human(display_long)|uniprotkb:CEP164(gene name)|psi-mi:CEP164(display_short)|uniprotkb:KIAA1052(gene name synonym)|uniprotkb:NPHP15(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267702|imex:IM-17681-22	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079416.1|ensembl:ENSG00000119242(gene)|ensembl:ENSG00000275035(gene)|ensembl:ENST00000238156(transcript)|ensembl:ENST00000632401(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033224|interpro:IPR039496|interpro:IPR040370|mint:Q53HC0|refseq:NP_001291886.1|refseq:NP_001291887.1|refseq:NP_001291888.1|refseq:NP_001291889.1|refseq:NP_001291890.1|refseq:XP_005253681.1|refseq:XP_016875473.1	ensembl:ENSG00000110274(gene)|ensembl:ENST00000278935(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055771.4|refseq:NP_001258862.1|refseq:XP_005271513.1|refseq:XP_005271514.1	-	-	-	figure legend:Supp Fig. 5F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2012/08/14	2014/10/16	rogid:Iu/FzTqEpzn8N5WUTt1OwoKWxyc9606	rogid:2KpJEO+xb35LM5rSOk1vGZTZ6Zc9606	intact-crc:4093B82AE4386D93|rigid:EkdMs4j2ZNXniaX4a2O7FHpzFZw	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9UPV0	uniprotkb:Q53HC0	intact:EBI-3937015|uniprotkb:Q9UFJ6|uniprotkb:Q9NVS0|uniprotkb:Q6PKH9|uniprotkb:Q7Z2X9|ensembl:ENSP00000278935	intact:EBI-719994|uniprotkb:Q9H697|uniprotkb:B3KNQ0|ensembl:ENSP00000238156|ensembl:ENSP00000488830	psi-mi:ce164_human(display_long)|uniprotkb:CEP164(gene name)|psi-mi:CEP164(display_short)|uniprotkb:KIAA1052(gene name synonym)|uniprotkb:NPHP15(gene name synonym)	psi-mi:ccd92_human(display_long)|uniprotkb:Limkain beta-2(gene name synonym)|uniprotkb:CCDC92(gene name)|psi-mi:CCDC92(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267683|imex:IM-17681-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110274(gene)|ensembl:ENST00000278935(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055771.4|refseq:NP_001258862.1|refseq:XP_005271513.1|refseq:XP_005271514.1	refseq:NP_079416.1|ensembl:ENSG00000119242(gene)|ensembl:ENSG00000275035(gene)|ensembl:ENST00000238156(transcript)|ensembl:ENST00000632401(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033224|interpro:IPR039496|interpro:IPR040370|mint:Q53HC0|refseq:NP_001291886.1|refseq:NP_001291887.1|refseq:NP_001291888.1|refseq:NP_001291889.1|refseq:NP_001291890.1|refseq:XP_005253681.1|refseq:XP_016875473.1	-	-	-	figure legend:Supp Fig. 5E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2012/08/14	2014/10/16	rogid:2KpJEO+xb35LM5rSOk1vGZTZ6Zc9606	rogid:Iu/FzTqEpzn8N5WUTt1OwoKWxyc9606	intact-crc:87C7D27397CBB327|rigid:EkdMs4j2ZNXniaX4a2O7FHpzFZw	false	ha tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q6IQ55	uniprotkb:Q9UPV0	intact:EBI-1050303|uniprotkb:O94932|uniprotkb:Q6ZN52|uniprotkb:Q8IVV1|ensembl:ENSP00000267890	intact:EBI-3937015|uniprotkb:Q9UFJ6|uniprotkb:Q9NVS0|uniprotkb:Q6PKH9|uniprotkb:Q7Z2X9|ensembl:ENSP00000278935	psi-mi:ttbk2_human(display_long)|uniprotkb:TTBK2(gene name)|psi-mi:TTBK2(display_short)|uniprotkb:KIAA0847(gene name synonym)	psi-mi:ce164_human(display_long)|uniprotkb:CEP164(gene name)|psi-mi:CEP164(display_short)|uniprotkb:KIAA1052(gene name synonym)|uniprotkb:NPHP15(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267686|imex:IM-17681-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_775771.3|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019894"(kinesin binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021681"(cerebellar granular layer development)|go:"GO:0021935"(cerebellar granule cell precursor tangential migration)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902817"(negative regulation of protein localization to microtubule)|go:"GO:1904527"(negative regulation of microtubule binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6U0K|rcsb pdb:6VRF|reactome:R-HSA-5620912|ensembl:ENSG00000128881(gene)|ensembl:ENST00000267890(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0004672"(protein kinase activity)	ensembl:ENSG00000110274(gene)|ensembl:ENST00000278935(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055771.4|refseq:NP_001258862.1|refseq:XP_005271513.1|refseq:XP_005271514.1	-	-	-	figure legend:Supp. Fig. 5G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2012/08/14	2014/10/16	rogid:XCTz5pJ+CJnvnlTXQwRM5gW/A389606	rogid:2KpJEO+xb35LM5rSOk1vGZTZ6Zc9606	intact-crc:3A76A2C863F4C9B8|rigid:y09p8EhJ5rod/iy3NpJumDiF87E	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9UPV0	uniprotkb:Q6IQ55	intact:EBI-3937015|uniprotkb:Q9UFJ6|uniprotkb:Q9NVS0|uniprotkb:Q6PKH9|uniprotkb:Q7Z2X9|ensembl:ENSP00000278935	intact:EBI-1050303|uniprotkb:O94932|uniprotkb:Q6ZN52|uniprotkb:Q8IVV1|ensembl:ENSP00000267890	psi-mi:ce164_human(display_long)|uniprotkb:CEP164(gene name)|psi-mi:CEP164(display_short)|uniprotkb:KIAA1052(gene name synonym)|uniprotkb:NPHP15(gene name synonym)	psi-mi:ttbk2_human(display_long)|uniprotkb:TTBK2(gene name)|psi-mi:TTBK2(display_short)|uniprotkb:KIAA0847(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267710|imex:IM-17681-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110274(gene)|ensembl:ENST00000278935(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055771.4|refseq:NP_001258862.1|refseq:XP_005271513.1|refseq:XP_005271514.1	refseq:NP_775771.3|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019894"(kinesin binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021681"(cerebellar granular layer development)|go:"GO:0021935"(cerebellar granule cell precursor tangential migration)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902817"(negative regulation of protein localization to microtubule)|go:"GO:1904527"(negative regulation of microtubule binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6U0K|rcsb pdb:6VRF|reactome:R-HSA-5620912|ensembl:ENSG00000128881(gene)|ensembl:ENST00000267890(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0004672"(protein kinase activity)	-	-	-	figure legend:Supp. Fig. 5H|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2012/08/14	2014/10/16	rogid:2KpJEO+xb35LM5rSOk1vGZTZ6Zc9606	rogid:XCTz5pJ+CJnvnlTXQwRM5gW/A389606	intact-crc:0C50AF03816F4285|rigid:y09p8EhJ5rod/iy3NpJumDiF87E	false	ha tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O75161	uniprotkb:Q16531	intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0	intact:EBI-350322|uniprotkb:A6NG77|uniprotkb:O15176|uniprotkb:Q13289|ensembl:ENSP00000301764|ensembl:ENSP00000506223|ensembl:ENSP00000506685|uniprotkb:Q58F96|uniprotkb:B2R648|uniprotkb:B4DG00	psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym)	psi-mi:ddb1_human(display_long)|uniprotkb:DDB1(gene name)|psi-mi:DDB1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym)|uniprotkb:DNA damage-binding protein a(gene name synonym)|uniprotkb:UV-damaged DNA-binding protein 1(gene name synonym)|uniprotkb:Xeroderma pigmentosum group E-complementing protein(gene name synonym)|uniprotkb:XPE-binding factor(gene name synonym)|uniprotkb:HBV X-associated protein 1(gene name synonym)|uniprotkb:XAP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267763|imex:IM-17681-28	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1	refseq:NP_001914.3|rcsb pdb:3I89|rcsb pdb:3I8C|rcsb pdb:3I8E|rcsb pdb:4A08|rcsb pdb:4A09|rcsb pdb:4A0A|rcsb pdb:4A0B|rcsb pdb:4A0K|rcsb pdb:4A0L|rcsb pdb:4A11|rcsb pdb:4CI1|rcsb pdb:4CI2|rcsb pdb:4CI3|rcsb pdb:4E54|rcsb pdb:4E5Z|rcsb pdb:4TZ4|rcsb pdb:5FQD|rcsb pdb:5HXB|rcsb pdb:5JK7|rcsb pdb:5V3O|rcsb pdb:6BN7|ensembl:ENSG00000167986(gene)|ensembl:ENST00000301764(transcript)|ensembl:ENST00000680367(transcript)|ensembl:ENST00000681803(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BOY|rcsb pdb:6DSZ|rcsb pdb:6FCV|rcsb pdb:6H0F|rcsb pdb:6H0G|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6SJ7|rcsb pdb:6TD3|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:6UML|rcsb pdb:6XK9|rcsb pdb:7LPS|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|interpro:IPR036322|mint:Q16531|rcsb pdb:2B5L|rcsb pdb:2B5M|rcsb pdb:2B5N|rcsb pdb:2HYE|rcsb pdb:3E0C|rcsb pdb:3EI1|rcsb pdb:3EI2|rcsb pdb:3EI3|rcsb pdb:3EI4|rcsb pdb:3I7H|rcsb pdb:3I7K|rcsb pdb:3I7L|rcsb pdb:3I7N|rcsb pdb:3I7O|rcsb pdb:3I7P|dip:DIP-430N	-	-	-	figure legend:Supp. Fig. 6C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/08/14	2014/10/16	rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606	rogid:qgMjZqvlsbGIGn2qM/pnLTtGyGM9606	intact-crc:D392463E9FD53120|rigid:KEHxo2loGVdVVKpls5wKSTUYpHI	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q16531	uniprotkb:Q9Y283	intact:EBI-350322|uniprotkb:A6NG77|uniprotkb:O15176|uniprotkb:Q13289|ensembl:ENSP00000301764|ensembl:ENSP00000506223|ensembl:ENSP00000506685|uniprotkb:Q58F96|uniprotkb:B2R648|uniprotkb:B4DG00	intact:EBI-751472|uniprotkb:Q5W0T6|uniprotkb:Q8IVX8|uniprotkb:Q9BRB9|uniprotkb:Q9Y488|uniprotkb:Q9Y498|uniprotkb:A2A2Y2|uniprotkb:Q2NKL0|ensembl:ENSP00000262457	psi-mi:ddb1_human(display_long)|uniprotkb:DDB1(gene name)|psi-mi:DDB1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym)|uniprotkb:DNA damage-binding protein a(gene name synonym)|uniprotkb:UV-damaged DNA-binding protein 1(gene name synonym)|uniprotkb:Xeroderma pigmentosum group E-complementing protein(gene name synonym)|uniprotkb:XPE-binding factor(gene name synonym)|uniprotkb:HBV X-associated protein 1(gene name synonym)|uniprotkb:XAP1(gene name synonym)	psi-mi:invs_human(display_long)|uniprotkb:Inversion of embryo turning homolog(gene name synonym)|uniprotkb:Nephrocystin-2(gene name synonym)|uniprotkb:INVS(gene name)|psi-mi:INVS(display_short)|uniprotkb:INV(gene name synonym)|uniprotkb:NPHP2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267757|imex:IM-17681-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001914.3|rcsb pdb:3I89|rcsb pdb:3I8C|rcsb pdb:3I8E|rcsb pdb:4A08|rcsb pdb:4A09|rcsb pdb:4A0A|rcsb pdb:4A0B|rcsb pdb:4A0K|rcsb pdb:4A0L|rcsb pdb:4A11|rcsb pdb:4CI1|rcsb pdb:4CI2|rcsb pdb:4CI3|rcsb pdb:4E54|rcsb pdb:4E5Z|rcsb pdb:4TZ4|rcsb pdb:5FQD|rcsb pdb:5HXB|rcsb pdb:5JK7|rcsb pdb:5V3O|rcsb pdb:6BN7|ensembl:ENSG00000167986(gene)|ensembl:ENST00000301764(transcript)|ensembl:ENST00000680367(transcript)|ensembl:ENST00000681803(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BOY|rcsb pdb:6DSZ|rcsb pdb:6FCV|rcsb pdb:6H0F|rcsb pdb:6H0G|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6SJ7|rcsb pdb:6TD3|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:6UML|rcsb pdb:6XK9|rcsb pdb:7LPS|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|interpro:IPR036322|mint:Q16531|rcsb pdb:2B5L|rcsb pdb:2B5M|rcsb pdb:2B5N|rcsb pdb:2HYE|rcsb pdb:3E0C|rcsb pdb:3EI1|rcsb pdb:3EI2|rcsb pdb:3EI3|rcsb pdb:3EI4|rcsb pdb:3I7H|rcsb pdb:3I7K|rcsb pdb:3I7L|rcsb pdb:3I7N|rcsb pdb:3I7O|rcsb pdb:3I7P|dip:DIP-430N	refseq:NP_055240.2|ensembl:ENSG00000119509(gene)|ensembl:ENST00000262457(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770	-	-	-	figure legend:Supp. Fig. 6C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/08/14	2014/10/16	rogid:qgMjZqvlsbGIGn2qM/pnLTtGyGM9606	rogid:GSK8P9P5/QrqxZL6oFgyWLdQ97Y9606	intact-crc:E56EB4DCF81163E0|rigid:b4YTgdJVBidcE55SYc3PCTF0Pdg	false	-	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:E1BJC2	uniprotkb:Q9UPV0	intact:EBI-6267628|ensembl:ENSBTAP00000008483	intact:EBI-3937015|uniprotkb:Q9UFJ6|uniprotkb:Q9NVS0|uniprotkb:Q6PKH9|uniprotkb:Q7Z2X9|ensembl:ENSP00000278935	psi-mi:e1bjc2_bovin(display_long)|uniprotkb:TTBK2(gene name)|psi-mi:TTBK2(display_short)	psi-mi:ce164_human(display_long)|uniprotkb:CEP164(gene name)|psi-mi:CEP164(display_short)|uniprotkb:KIAA1052(gene name synonym)|uniprotkb:NPHP15(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267626|imex:IM-17681-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSBTAG00000006470(gene)|ensembl:ENSBTAT00000008483(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019894"(kinesin binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:1902817"(negative regulation of protein localization to microtubule)|go:"GO:1904527"(negative regulation of microtubule binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:XP_010807501.1|refseq:XP_010807502.1|refseq:XP_015328607.1|refseq:XP_015328608.1|refseq:NP_001193000.1	ensembl:ENSG00000110274(gene)|ensembl:ENST00000278935(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055771.4|refseq:NP_001258862.1|refseq:XP_005271513.1|refseq:XP_005271514.1	-	-	-	figure legend:Supp Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2012/08/14	2014/10/16	rogid:Zt0faj+miuVAMZEx89B9vkEItyY9913	rogid:2KpJEO+xb35LM5rSOk1vGZTZ6Zc9606	intact-crc:02ED91E0D2B03D83|rigid:coq8NW0yQuy0xdSdyY3IOmY2624	false	sufficient binding region:717-1064	sufficient binding region:1-550	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UPV0	uniprotkb:Q53HC0	intact:EBI-3937015|uniprotkb:Q9UFJ6|uniprotkb:Q9NVS0|uniprotkb:Q6PKH9|uniprotkb:Q7Z2X9|ensembl:ENSP00000278935	intact:EBI-719994|uniprotkb:Q9H697|uniprotkb:B3KNQ0|ensembl:ENSP00000238156|ensembl:ENSP00000488830	psi-mi:ce164_human(display_long)|uniprotkb:CEP164(gene name)|psi-mi:CEP164(display_short)|uniprotkb:KIAA1052(gene name synonym)|uniprotkb:NPHP15(gene name synonym)	psi-mi:ccd92_human(display_long)|uniprotkb:Limkain beta-2(gene name synonym)|uniprotkb:CCDC92(gene name)|psi-mi:CCDC92(display_short)	psi-mi:"MI:0096"(pull down)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267663|imex:IM-17681-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110274(gene)|ensembl:ENST00000278935(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055771.4|refseq:NP_001258862.1|refseq:XP_005271513.1|refseq:XP_005271514.1	refseq:NP_079416.1|ensembl:ENSG00000119242(gene)|ensembl:ENSG00000275035(gene)|ensembl:ENST00000238156(transcript)|ensembl:ENST00000632401(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033224|interpro:IPR039496|interpro:IPR040370|mint:Q53HC0|refseq:NP_001291886.1|refseq:NP_001291887.1|refseq:NP_001291888.1|refseq:NP_001291889.1|refseq:NP_001291890.1|refseq:XP_005253681.1|refseq:XP_016875473.1	-	-	-	figure legend:Supp Fig. 5D|caution:Binding region length is given as 1101-1640 in the text. As the known length of the protein is 1460, it has been assumed that two digits have been reversed.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/08/14	2014/10/16	rogid:2KpJEO+xb35LM5rSOk1vGZTZ6Zc9606	rogid:Iu/FzTqEpzn8N5WUTt1OwoKWxyc9606	intact-crc:AA6CBD676326AAC1|rigid:EkdMs4j2ZNXniaX4a2O7FHpzFZw	false	sufficient binding region:1-550|glutathione s tranferase tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9UPV0	uniprotkb:Q6IQ55	intact:EBI-3937015|uniprotkb:Q9UFJ6|uniprotkb:Q9NVS0|uniprotkb:Q6PKH9|uniprotkb:Q7Z2X9|ensembl:ENSP00000278935	intact:EBI-1050303|uniprotkb:O94932|uniprotkb:Q6ZN52|uniprotkb:Q8IVV1|ensembl:ENSP00000267890	psi-mi:ce164_human(display_long)|uniprotkb:CEP164(gene name)|psi-mi:CEP164(display_short)|uniprotkb:KIAA1052(gene name synonym)|uniprotkb:NPHP15(gene name synonym)	psi-mi:ttbk2_human(display_long)|uniprotkb:TTBK2(gene name)|psi-mi:TTBK2(display_short)|uniprotkb:KIAA0847(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267655|imex:IM-17681-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110274(gene)|ensembl:ENST00000278935(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055771.4|refseq:NP_001258862.1|refseq:XP_005271513.1|refseq:XP_005271514.1	refseq:NP_775771.3|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019894"(kinesin binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021681"(cerebellar granular layer development)|go:"GO:0021935"(cerebellar granule cell precursor tangential migration)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902817"(negative regulation of protein localization to microtubule)|go:"GO:1904527"(negative regulation of microtubule binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6U0K|rcsb pdb:6VRF|reactome:R-HSA-5620912|ensembl:ENSG00000128881(gene)|ensembl:ENST00000267890(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0004672"(protein kinase activity)	-	-	-	figure legend:Supp. Fig. 5D|comment:Peptides spanning regions across the full-length of Cep164 all bound to TTBK2.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/08/14	2014/10/16	rogid:2KpJEO+xb35LM5rSOk1vGZTZ6Zc9606	rogid:XCTz5pJ+CJnvnlTXQwRM5gW/A389606	intact-crc:43E9E0C031E0DA50|rigid:y09p8EhJ5rod/iy3NpJumDiF87E	false	glutathione s tranferase tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9UPV0	uniprotkb:Q92997	intact:EBI-3937015|uniprotkb:Q9UFJ6|uniprotkb:Q9NVS0|uniprotkb:Q6PKH9|uniprotkb:Q7Z2X9|ensembl:ENSP00000278935	intact:EBI-739789|uniprotkb:O14642|uniprotkb:Q13531|uniprotkb:Q8N5E9|uniprotkb:Q92607|uniprotkb:D3DNT0|intact:EBI-11081380|uniprotkb:B4E3E5|ensembl:ENSP00000316054	psi-mi:ce164_human(display_long)|uniprotkb:CEP164(gene name)|psi-mi:CEP164(display_short)|uniprotkb:KIAA1052(gene name synonym)|uniprotkb:NPHP15(gene name synonym)	psi-mi:dvl3_human(display_long)|uniprotkb:DVL3(gene name)|psi-mi:DVL3(display_short)|uniprotkb:KIAA0208(gene name synonym)|uniprotkb:DSH homolog 3(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267775|imex:IM-17681-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110274(gene)|ensembl:ENST00000278935(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055771.4|refseq:NP_001258862.1|refseq:XP_005271513.1|refseq:XP_005271514.1	refseq:NP_004414.3|dip:DIP-34509N|ensembl:ENSG00000161202(gene)|ensembl:ENST00000313143(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0042493"|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q92997|rcsb pdb:6V7O|rcsb pdb:6ZC6|rcsb pdb:6ZC8|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-4086400|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-9673324	go:"GO:0000775"(chromosome, centromeric region)	-	-	figure legend:Supp. Fig. 6E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/08/14	2014/10/16	rogid:2KpJEO+xb35LM5rSOk1vGZTZ6Zc9606	rogid:yJ3YIp5IhvKTQwa3bK5yTjNyqXk9606	intact-crc:702D51CFFAACFDEC|rigid:6Eou6L6f3WhSUV45QrBSv29ZbbE	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q2M1K9	uniprotkb:P09874	intact:EBI-950016|intact:EBI-28976649|ensembl:ENSP00000455426|uniprotkb:O94860|uniprotkb:Q9NZ13|uniprotkb:Q76N04	intact:EBI-355676|uniprotkb:Q8IUZ9|uniprotkb:B1ANJ4|ensembl:ENSP00000355759	psi-mi:zn423_human(display_long)|uniprotkb:OAZ(gene name synonym)|uniprotkb:Olf1/EBF-associated zinc finger protein(gene name synonym)|uniprotkb:Smad- and Olf-interacting zinc finger protein(gene name synonym)|uniprotkb:ZNF423(gene name)|psi-mi:ZNF423(display_short)|uniprotkb:KIAA0760(gene name synonym)|uniprotkb:NPHP14(gene name synonym)	psi-mi:parp1_human(display_long)|uniprotkb:PARP1(gene name)|psi-mi:PARP1(display_short)|uniprotkb:ADPRT(gene name synonym)|uniprotkb:PPOL(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267373|imex:IM-17681-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0021930"(cerebellar granule cell precursor proliferation)|go:"GO:0021938"(smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q2M1K9|rcsb pdb:2MDG|ensembl:ENSG00000102935(gene)|ensembl:ENST00000561648(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007219"(Notch signaling pathway)|refseq:NP_055884.2|ensembl:ENSP00000455426|ensembl:ENST00000562520|ensembl:ENSP00000457664|ensembl:ENST00000562871|ensembl:ENSP00000457928|refseq:NP_001258549.1|refseq:XP_005255913.1|refseq:XP_016878567.1|refseq:XP_016878566.1	refseq:NP_001609.2|rcsb pdb:7AAC|rcsb pdb:7AAD|rcsb pdb:6NRJ|rcsb pdb:6NTU|rcsb pdb:7CMW|rcsb pdb:6VKK|rcsb pdb:7KK2|rcsb pdb:7KK3|rcsb pdb:7KK4|rcsb pdb:7KK5|rcsb pdb:7KK6|reactome:R-HSA-110362|reactome:R-HSA-192814|reactome:R-HSA-2173795|reactome:R-HSA-3108214|reactome:R-HSA-5685939|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|rcsb pdb:6VKO|rcsb pdb:6VKQ|rcsb pdb:6XVW|rcsb pdb:7AAA|rcsb pdb:7AAB|ensembl:ENSG00000143799(gene)|ensembl:ENST00000366794(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904044"(response to aldosterone)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|mint:P09874|rcsb pdb:1UK0|rcsb pdb:1UK1|rcsb pdb:1WOK|rcsb pdb:2COK|rcsb pdb:2CR9|rcsb pdb:2CS2|rcsb pdb:2DMJ|rcsb pdb:2JVN|go:"GO:1903827"|rcsb pdb:2L30|rcsb pdb:2N8A|rcsb pdb:2RCW|rcsb pdb:2RD6|rcsb pdb:2RIQ|rcsb pdb:2L31|rcsb pdb:3GJW|rcsb pdb:3GN7|rcsb pdb:3L3L|rcsb pdb:3L3M|rcsb pdb:3OD8|rcsb pdb:3ODA|rcsb pdb:3ODC|rcsb pdb:3ODE|rcsb pdb:4AV1|rcsb pdb:4DQY|rcsb pdb:4GV7|rcsb pdb:4HHY|rcsb pdb:4HHZ|rcsb pdb:4L6S|rcsb pdb:4OPX|rcsb pdb:4OQA|rcsb pdb:4OQB|rcsb pdb:4PJT|rcsb pdb:4R5W|rcsb pdb:4R6E|rcsb pdb:4RV6|rcsb pdb:4UND|rcsb pdb:4UXB|rcsb pdb:4XHU|rcsb pdb:5A00|rcsb pdb:5DS3|rcsb pdb:5HA9|rcsb pdb:5KPN|rcsb pdb:5KPO|rcsb pdb:5KPP|rcsb pdb:5KPQ|rcsb pdb:5WRQ|rcsb pdb:5WRY|rcsb pdb:5WRZ|rcsb pdb:5WS0|rcsb pdb:5WS1|rcsb pdb:5WTC|rcsb pdb:4ZZZ|rcsb pdb:5XSR|rcsb pdb:5XST|rcsb pdb:5XSU|rcsb pdb:6BHV|rcsb pdb:6GHK|rcsb pdb:6M3I|rcsb pdb:6NRF|rcsb pdb:6NRG|rcsb pdb:6NRH|rcsb pdb:6NRI|dip:DIP-38N	-	-	-	figure legend:Fig. 2E|comment:"ZNF423: p.P506fsX43 is a frame-shift mutation causing a truncation at Pro-506.."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-p19)|taxid:10090(Mus musculus embryonic teratocarcinoma cell line,  epithelial-like, induced by retinoic acid)	-	2012/08/14	2014/10/16	rogid:MvDTye6jC364XYE9jlFukJM+fAM9606	rogid:VC+4HLilGJuoiTbk4/fSeRw9+iY9606	intact-crc:C6861487BD247560|rigid:x5BV4mmlUDt+z/jK0HtCR2cNp+I	false	necessary binding region:507-1284|flag tag:n-n	v5 tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P09874	uniprotkb:Q2M1K9	intact:EBI-355676|uniprotkb:Q8IUZ9|uniprotkb:B1ANJ4|ensembl:ENSP00000355759	intact:EBI-950016|intact:EBI-28976649|ensembl:ENSP00000455426|uniprotkb:O94860|uniprotkb:Q9NZ13|uniprotkb:Q76N04	psi-mi:parp1_human(display_long)|uniprotkb:PARP1(gene name)|psi-mi:PARP1(display_short)|uniprotkb:ADPRT(gene name synonym)|uniprotkb:PPOL(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym)	psi-mi:zn423_human(display_long)|uniprotkb:OAZ(gene name synonym)|uniprotkb:Olf1/EBF-associated zinc finger protein(gene name synonym)|uniprotkb:Smad- and Olf-interacting zinc finger protein(gene name synonym)|uniprotkb:ZNF423(gene name)|psi-mi:ZNF423(display_short)|uniprotkb:KIAA0760(gene name synonym)|uniprotkb:NPHP14(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267362|imex:IM-17681-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001609.2|rcsb pdb:7AAC|rcsb pdb:7AAD|rcsb pdb:6NRJ|rcsb pdb:6NTU|rcsb pdb:7CMW|rcsb pdb:6VKK|rcsb pdb:7KK2|rcsb pdb:7KK3|rcsb pdb:7KK4|rcsb pdb:7KK5|rcsb pdb:7KK6|reactome:R-HSA-110362|reactome:R-HSA-192814|reactome:R-HSA-2173795|reactome:R-HSA-3108214|reactome:R-HSA-5685939|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|rcsb pdb:6VKO|rcsb pdb:6VKQ|rcsb pdb:6XVW|rcsb pdb:7AAA|rcsb pdb:7AAB|ensembl:ENSG00000143799(gene)|ensembl:ENST00000366794(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904044"(response to aldosterone)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|mint:P09874|rcsb pdb:1UK0|rcsb pdb:1UK1|rcsb pdb:1WOK|rcsb pdb:2COK|rcsb pdb:2CR9|rcsb pdb:2CS2|rcsb pdb:2DMJ|rcsb pdb:2JVN|go:"GO:1903827"|rcsb pdb:2L30|rcsb pdb:2N8A|rcsb pdb:2RCW|rcsb pdb:2RD6|rcsb pdb:2RIQ|rcsb pdb:2L31|rcsb pdb:3GJW|rcsb pdb:3GN7|rcsb pdb:3L3L|rcsb pdb:3L3M|rcsb pdb:3OD8|rcsb pdb:3ODA|rcsb pdb:3ODC|rcsb pdb:3ODE|rcsb pdb:4AV1|rcsb pdb:4DQY|rcsb pdb:4GV7|rcsb pdb:4HHY|rcsb pdb:4HHZ|rcsb pdb:4L6S|rcsb pdb:4OPX|rcsb pdb:4OQA|rcsb pdb:4OQB|rcsb pdb:4PJT|rcsb pdb:4R5W|rcsb pdb:4R6E|rcsb pdb:4RV6|rcsb pdb:4UND|rcsb pdb:4UXB|rcsb pdb:4XHU|rcsb pdb:5A00|rcsb pdb:5DS3|rcsb pdb:5HA9|rcsb pdb:5KPN|rcsb pdb:5KPO|rcsb pdb:5KPP|rcsb pdb:5KPQ|rcsb pdb:5WRQ|rcsb pdb:5WRY|rcsb pdb:5WRZ|rcsb pdb:5WS0|rcsb pdb:5WS1|rcsb pdb:5WTC|rcsb pdb:4ZZZ|rcsb pdb:5XSR|rcsb pdb:5XST|rcsb pdb:5XSU|rcsb pdb:6BHV|rcsb pdb:6GHK|rcsb pdb:6M3I|rcsb pdb:6NRF|rcsb pdb:6NRG|rcsb pdb:6NRH|rcsb pdb:6NRI|dip:DIP-38N	go:"GO:0021930"(cerebellar granule cell precursor proliferation)|go:"GO:0021938"(smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q2M1K9|rcsb pdb:2MDG|ensembl:ENSG00000102935(gene)|ensembl:ENST00000561648(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007219"(Notch signaling pathway)|refseq:NP_055884.2|ensembl:ENSP00000455426|ensembl:ENST00000562520|ensembl:ENSP00000457664|ensembl:ENST00000562871|ensembl:ENSP00000457928|refseq:NP_001258549.1|refseq:XP_005255913.1|refseq:XP_016878567.1|refseq:XP_016878566.1	-	-	-	figure legend:Fig. 2E|comment:"ZNF423: p.P506fsX43 is a frame-shift mutation causing a truncation at pro-506.."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-p19)|taxid:10090(Mus musculus embryonic teratocarcinoma cell line,  epithelial-like, induced by retinoic acid)	-	2012/08/14	2014/10/16	rogid:VC+4HLilGJuoiTbk4/fSeRw9+iY9606	rogid:MvDTye6jC364XYE9jlFukJM+fAM9606	intact-crc:01BF531EFDAF9073|rigid:x5BV4mmlUDt+z/jK0HtCR2cNp+I	false	v5 tag:n-n	flag tag:n-n|necessary binding region:507-1284	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O14757	uniprotkb:Q92993	intact:EBI-974488|ensembl:ENSP00000388648|ensembl:ENSP00000412504|ensembl:ENSP00000432890|ensembl:ENSP00000435371|ensembl:ENSP00000481616|uniprotkb:B4DDD0|uniprotkb:F5H7S4|uniprotkb:A8K934|uniprotkb:B4DSK3|uniprotkb:B5BTY6|uniprotkb:H2BI51	intact:EBI-399080|uniprotkb:O95624|uniprotkb:Q13430|uniprotkb:Q17RW5|uniprotkb:Q6GSE8|uniprotkb:Q9BWK7|uniprotkb:Q561W3|intact:EBI-28987721|ensembl:ENSP00000366245|uniprotkb:C9JL99|uniprotkb:B4E3C7	psi-mi:chk1_human(display_long)|uniprotkb:CHEK1(gene name)|psi-mi:CHEK1(display_short)|uniprotkb:CHK1(gene name synonym)|uniprotkb:CHK1 checkpoint homolog(gene name synonym)|uniprotkb:Checkpoint kinase-1(gene name synonym)|uniprotkb:Cell cycle checkpoint kinase(gene name synonym)	psi-mi:kat5_human(display_long)|uniprotkb:KAT5(gene name)|psi-mi:KAT5(display_short)|uniprotkb:TIP60(gene name synonym)|uniprotkb:HTATIP(gene name synonym)|uniprotkb:Lysine acetyltransferase 5(gene name synonym)|uniprotkb:"cPLA(2)-interacting protein"(gene name synonym)|uniprotkb:Histone acetyltransferase HTATIP(gene name synonym)|uniprotkb:60 kDa Tat-interactive protein(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267516|imex:IM-17681-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000149554(gene)|ensembl:ENST00000428830(transcript)|ensembl:ENST00000438015(transcript)|ensembl:ENST00000524737(transcript)|ensembl:ENST00000532449(transcript)|ensembl:ENST00000534070(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010767"(regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035402"("histone kinase activity (H3-T11 specific)")|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0046602"(regulation of mitotic centrosome separation)|go:"GO:0048096"|go:"GO:0070317"(negative regulation of G0 to G1 transition)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090399"(replicative senescence)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:2000615"(regulation of histone H3-K9 acetylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR034670|mint:O14757|rcsb pdb:1IA8|rcsb pdb:1NVQ|rcsb pdb:1NVR|rcsb pdb:1NVS|rcsb pdb:1ZLT|rcsb pdb:1ZYS|rcsb pdb:2AYP|rcsb pdb:2BR1|rcsb pdb:2BRB|rcsb pdb:2BRG|rcsb pdb:2BRH|rcsb pdb:2BRM|rcsb pdb:2BRN|rcsb pdb:2BRO|rcsb pdb:2C3J|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|rcsb pdb:2C3K|rcsb pdb:2C3L|rcsb pdb:2CGU|rcsb pdb:2CGV|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0006997"(nucleus organization)|rcsb pdb:2CGX|rcsb pdb:2E9N|rcsb pdb:2E9O|rcsb pdb:2E9P|rcsb pdb:2E9U|rcsb pdb:2E9V|rcsb pdb:2GDO|rcsb pdb:2GHG|rcsb pdb:2HOG|rcsb pdb:2HXL|rcsb pdb:2HXQ|rcsb pdb:2CGW|rcsb pdb:2HY0|rcsb pdb:2QHM|rcsb pdb:2QHN|rcsb pdb:2R0U|rcsb pdb:2WMQ|rcsb pdb:2WMR|rcsb pdb:2WMS|rcsb pdb:2WMT|rcsb pdb:2WMU|rcsb pdb:2YM7|rcsb pdb:2YM8|rcsb pdb:2YWP|rcsb pdb:3F9N|rcsb pdb:3JVR|rcsb pdb:3JVS|rcsb pdb:3NLB|rcsb pdb:3OT3|rcsb pdb:3OT8|rcsb pdb:3PA3|rcsb pdb:3PA4|rcsb pdb:2WMV|rcsb pdb:3PA5|rcsb pdb:3TKH|rcsb pdb:3TKI|rcsb pdb:2WMW|rcsb pdb:3U9N|rcsb pdb:4FSM|rcsb pdb:4FSN|rcsb pdb:2WMX|rcsb pdb:4FSQ|rcsb pdb:2X8D|rcsb pdb:2X8E|rcsb pdb:4FSR|rcsb pdb:4FST|rcsb pdb:4FSU|rcsb pdb:4FSW|rcsb pdb:4FSY|rcsb pdb:2X8I|rcsb pdb:2XEY|rcsb pdb:2XEZ|rcsb pdb:2XF0|rcsb pdb:2YDI|rcsb pdb:2YDJ|rcsb pdb:2YDK|rcsb pdb:2YER|rcsb pdb:2YEX|rcsb pdb:2YM3|rcsb pdb:2YM4|rcsb pdb:2YM5|rcsb pdb:2YM6|rcsb pdb:4FSZ|rcsb pdb:4FT0|rcsb pdb:4FT3|rcsb pdb:4FT5|rcsb pdb:4FT7|rcsb pdb:4FTA|rcsb pdb:4FTC|rcsb pdb:4FTI|rcsb pdb:4FTJ|rcsb pdb:4FTK|rcsb pdb:4FTL|rcsb pdb:4FTM|rcsb pdb:4FTN|rcsb pdb:4FTO|rcsb pdb:4FTQ|rcsb pdb:4FTR|rcsb pdb:4FTT|rcsb pdb:4FTU|rcsb pdb:4GH2|rcsb pdb:4FT9|rcsb pdb:4HYH|rcsb pdb:4HYI|rcsb pdb:4JIK|rcsb pdb:4QYE|rcsb pdb:4QYF|rcsb pdb:4QYG|rcsb pdb:4QYH|rcsb pdb:4RVK|rcsb pdb:4RVL|rcsb pdb:4RVM|rcsb pdb:5DLS|rcsb pdb:5F4N|rcsb pdb:5OOP|rcsb pdb:5OOR|rcsb pdb:5OOT|rcsb pdb:5OP2|rcsb pdb:5OP4|rcsb pdb:5OP5|rcsb pdb:5OP7|rcsb pdb:5OPB|rcsb pdb:5OPR|rcsb pdb:5OPS|rcsb pdb:5OPU|rcsb pdb:5OPV|rcsb pdb:5OQ5|rcsb pdb:5OQ6|rcsb pdb:5OQ7|rcsb pdb:5OQ8|rcsb pdb:5WI2|rcsb pdb:6FC8|rcsb pdb:6FCF|rcsb pdb:6FCK|rcsb pdb:7AKM|rcsb pdb:7AKO|rcsb pdb:7MCK|reactome:R-HSA-1433557|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-69601|reactome:R-HSA-75035|reactome:R-HSA-8953750|reactome:R-HSA-176187|refseq:NP_001107593.1|refseq:NP_001107594.1|refseq:NP_001265.2|refseq:NP_001231775.1|refseq:XP_016872635.1|refseq:NP_001317357.1|dip:DIP-24182N	refseq:NP_006379.2|refseq:NP_874368.1|refseq:NP_874369.1|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-9018519|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090398"(cellular senescence)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR000953(Chromo domain)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037995|interpro:IPR040706|rcsb pdb:2EKO|rcsb pdb:2OU2|rcsb pdb:4QQG|reactome:R-HSA-201722|reactome:R-HSA-2559586|reactome:R-HSA-3214847|reactome:R-HSA-5685938|ensembl:ENSG00000172977(gene)|ensembl:ENST00000377046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032777"(Piccolo NuA4 histone acetyltransferase complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_001193762.1|ensembl:ENST00000341318|ensembl:ENSP00000340330|ensembl:ENST00000352980|ensembl:ENSP00000344955|ensembl:ENSP00000366245|ensembl:ENST00000530446|ensembl:ENSP00000434765|dip:DIP-5998N	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 4P|agonist:Ultra-violet light|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2012/08/14	2014/10/16	rogid:S6QMFtpTWlBPrg6GN6b/1pgFCg09606	rogid:JvtMfge2Q7fuGOTLSWqR3syL/3s9606	intact-crc:BC9940DCDC4BA828|rigid:lY+yS3O6EQ4O5hCesiYv01Z32tc	false	O-phospho-L-serine:317-317	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:O14757	uniprotkb:Q9UPV0	intact:EBI-974488|ensembl:ENSP00000388648|ensembl:ENSP00000412504|ensembl:ENSP00000432890|ensembl:ENSP00000435371|ensembl:ENSP00000481616|uniprotkb:B4DDD0|uniprotkb:F5H7S4|uniprotkb:A8K934|uniprotkb:B4DSK3|uniprotkb:B5BTY6|uniprotkb:H2BI51	intact:EBI-3937015|uniprotkb:Q9UFJ6|uniprotkb:Q9NVS0|uniprotkb:Q6PKH9|uniprotkb:Q7Z2X9|ensembl:ENSP00000278935	psi-mi:chk1_human(display_long)|uniprotkb:CHEK1(gene name)|psi-mi:CHEK1(display_short)|uniprotkb:CHK1(gene name synonym)|uniprotkb:CHK1 checkpoint homolog(gene name synonym)|uniprotkb:Checkpoint kinase-1(gene name synonym)|uniprotkb:Cell cycle checkpoint kinase(gene name synonym)	psi-mi:ce164_human(display_long)|uniprotkb:CEP164(gene name)|psi-mi:CEP164(display_short)|uniprotkb:KIAA1052(gene name synonym)|uniprotkb:NPHP15(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267508|imex:IM-17681-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000149554(gene)|ensembl:ENST00000428830(transcript)|ensembl:ENST00000438015(transcript)|ensembl:ENST00000524737(transcript)|ensembl:ENST00000532449(transcript)|ensembl:ENST00000534070(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010767"(regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035402"("histone kinase activity (H3-T11 specific)")|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0046602"(regulation of mitotic centrosome separation)|go:"GO:0048096"|go:"GO:0070317"(negative regulation of G0 to G1 transition)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090399"(replicative senescence)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:2000615"(regulation of histone H3-K9 acetylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR034670|mint:O14757|rcsb pdb:1IA8|rcsb pdb:1NVQ|rcsb pdb:1NVR|rcsb pdb:1NVS|rcsb pdb:1ZLT|rcsb pdb:1ZYS|rcsb pdb:2AYP|rcsb pdb:2BR1|rcsb pdb:2BRB|rcsb pdb:2BRG|rcsb pdb:2BRH|rcsb pdb:2BRM|rcsb pdb:2BRN|rcsb pdb:2BRO|rcsb pdb:2C3J|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|rcsb pdb:2C3K|rcsb pdb:2C3L|rcsb pdb:2CGU|rcsb pdb:2CGV|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0006997"(nucleus organization)|rcsb pdb:2CGX|rcsb pdb:2E9N|rcsb pdb:2E9O|rcsb pdb:2E9P|rcsb pdb:2E9U|rcsb pdb:2E9V|rcsb pdb:2GDO|rcsb pdb:2GHG|rcsb pdb:2HOG|rcsb pdb:2HXL|rcsb pdb:2HXQ|rcsb pdb:2CGW|rcsb pdb:2HY0|rcsb pdb:2QHM|rcsb pdb:2QHN|rcsb pdb:2R0U|rcsb pdb:2WMQ|rcsb pdb:2WMR|rcsb pdb:2WMS|rcsb pdb:2WMT|rcsb pdb:2WMU|rcsb pdb:2YM7|rcsb pdb:2YM8|rcsb pdb:2YWP|rcsb pdb:3F9N|rcsb pdb:3JVR|rcsb pdb:3JVS|rcsb pdb:3NLB|rcsb pdb:3OT3|rcsb pdb:3OT8|rcsb pdb:3PA3|rcsb pdb:3PA4|rcsb pdb:2WMV|rcsb pdb:3PA5|rcsb pdb:3TKH|rcsb pdb:3TKI|rcsb pdb:2WMW|rcsb pdb:3U9N|rcsb pdb:4FSM|rcsb pdb:4FSN|rcsb pdb:2WMX|rcsb pdb:4FSQ|rcsb pdb:2X8D|rcsb pdb:2X8E|rcsb pdb:4FSR|rcsb pdb:4FST|rcsb pdb:4FSU|rcsb pdb:4FSW|rcsb pdb:4FSY|rcsb pdb:2X8I|rcsb pdb:2XEY|rcsb pdb:2XEZ|rcsb pdb:2XF0|rcsb pdb:2YDI|rcsb pdb:2YDJ|rcsb pdb:2YDK|rcsb pdb:2YER|rcsb pdb:2YEX|rcsb pdb:2YM3|rcsb pdb:2YM4|rcsb pdb:2YM5|rcsb pdb:2YM6|rcsb pdb:4FSZ|rcsb pdb:4FT0|rcsb pdb:4FT3|rcsb pdb:4FT5|rcsb pdb:4FT7|rcsb pdb:4FTA|rcsb pdb:4FTC|rcsb pdb:4FTI|rcsb pdb:4FTJ|rcsb pdb:4FTK|rcsb pdb:4FTL|rcsb pdb:4FTM|rcsb pdb:4FTN|rcsb pdb:4FTO|rcsb pdb:4FTQ|rcsb pdb:4FTR|rcsb pdb:4FTT|rcsb pdb:4FTU|rcsb pdb:4GH2|rcsb pdb:4FT9|rcsb pdb:4HYH|rcsb pdb:4HYI|rcsb pdb:4JIK|rcsb pdb:4QYE|rcsb pdb:4QYF|rcsb pdb:4QYG|rcsb pdb:4QYH|rcsb pdb:4RVK|rcsb pdb:4RVL|rcsb pdb:4RVM|rcsb pdb:5DLS|rcsb pdb:5F4N|rcsb pdb:5OOP|rcsb pdb:5OOR|rcsb pdb:5OOT|rcsb pdb:5OP2|rcsb pdb:5OP4|rcsb pdb:5OP5|rcsb pdb:5OP7|rcsb pdb:5OPB|rcsb pdb:5OPR|rcsb pdb:5OPS|rcsb pdb:5OPU|rcsb pdb:5OPV|rcsb pdb:5OQ5|rcsb pdb:5OQ6|rcsb pdb:5OQ7|rcsb pdb:5OQ8|rcsb pdb:5WI2|rcsb pdb:6FC8|rcsb pdb:6FCF|rcsb pdb:6FCK|rcsb pdb:7AKM|rcsb pdb:7AKO|rcsb pdb:7MCK|reactome:R-HSA-1433557|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-69601|reactome:R-HSA-75035|reactome:R-HSA-8953750|reactome:R-HSA-176187|refseq:NP_001107593.1|refseq:NP_001107594.1|refseq:NP_001265.2|refseq:NP_001231775.1|refseq:XP_016872635.1|refseq:NP_001317357.1|dip:DIP-24182N	ensembl:ENSG00000110274(gene)|ensembl:ENST00000278935(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055771.4|refseq:NP_001258862.1|refseq:XP_005271513.1|refseq:XP_005271514.1	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 4O, 4N|agonist:Ultra-violet light|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2012/08/14	2014/10/16	rogid:S6QMFtpTWlBPrg6GN6b/1pgFCg09606	rogid:2KpJEO+xb35LM5rSOk1vGZTZ6Zc9606	intact-crc:7D2EEFE4AD261754|rigid:yGDPDvXMZqrpoLbC6nMfKqLCvBQ	false	O-phospho-L-serine:317-317	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q92993	uniprotkb:Q9UPV0	intact:EBI-399080|uniprotkb:O95624|uniprotkb:Q13430|uniprotkb:Q17RW5|uniprotkb:Q6GSE8|uniprotkb:Q9BWK7|uniprotkb:Q561W3|intact:EBI-28987721|ensembl:ENSP00000366245|uniprotkb:C9JL99|uniprotkb:B4E3C7	intact:EBI-3937015|uniprotkb:Q9UFJ6|uniprotkb:Q9NVS0|uniprotkb:Q6PKH9|uniprotkb:Q7Z2X9|ensembl:ENSP00000278935	psi-mi:kat5_human(display_long)|uniprotkb:KAT5(gene name)|psi-mi:KAT5(display_short)|uniprotkb:TIP60(gene name synonym)|uniprotkb:HTATIP(gene name synonym)|uniprotkb:Lysine acetyltransferase 5(gene name synonym)|uniprotkb:"cPLA(2)-interacting protein"(gene name synonym)|uniprotkb:Histone acetyltransferase HTATIP(gene name synonym)|uniprotkb:60 kDa Tat-interactive protein(gene name synonym)	psi-mi:ce164_human(display_long)|uniprotkb:CEP164(gene name)|psi-mi:CEP164(display_short)|uniprotkb:KIAA1052(gene name synonym)|uniprotkb:NPHP15(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267482|imex:IM-17681-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006379.2|refseq:NP_874368.1|refseq:NP_874369.1|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-9018519|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090398"(cellular senescence)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR000953(Chromo domain)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037995|interpro:IPR040706|rcsb pdb:2EKO|rcsb pdb:2OU2|rcsb pdb:4QQG|reactome:R-HSA-201722|reactome:R-HSA-2559586|reactome:R-HSA-3214847|reactome:R-HSA-5685938|ensembl:ENSG00000172977(gene)|ensembl:ENST00000377046(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032777"(Piccolo NuA4 histone acetyltransferase complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_001193762.1|ensembl:ENST00000341318|ensembl:ENSP00000340330|ensembl:ENST00000352980|ensembl:ENSP00000344955|ensembl:ENSP00000366245|ensembl:ENST00000530446|ensembl:ENSP00000434765|dip:DIP-5998N	ensembl:ENSG00000110274(gene)|ensembl:ENST00000278935(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055771.4|refseq:NP_001258862.1|refseq:XP_005271513.1|refseq:XP_005271514.1	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 4L, 4M|agonist:Ultra-violet light|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2012/08/14	2014/10/16	rogid:JvtMfge2Q7fuGOTLSWqR3syL/3s9606	rogid:2KpJEO+xb35LM5rSOk1vGZTZ6Zc9606	intact-crc:B8B7C1BE012741E3|rigid:HBiL43O06ZcKM+iQx6BMFMVQaYw	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:O15078	uniprotkb:Q2M1K9	intact:EBI-1811944|uniprotkb:Q1PSK5|uniprotkb:Q66GS8|uniprotkb:Q9H2G6|uniprotkb:Q9H6Q7|uniprotkb:Q9H8I0|ensembl:ENSP00000448012	intact:EBI-950016|intact:EBI-28976649|ensembl:ENSP00000455426|uniprotkb:O94860|uniprotkb:Q9NZ13|uniprotkb:Q76N04	psi-mi:ce290_human(display_long)|uniprotkb:CEP290(gene name)|psi-mi:CEP290(display_short)|uniprotkb:KIAA0373(gene name synonym)|uniprotkb:NPHP6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Tumor antigen se2-2(gene name synonym)|uniprotkb:Cancer/testis antigen 87(gene name synonym)|uniprotkb:BBS14(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein(gene name synonym)	psi-mi:zn423_human(display_long)|uniprotkb:OAZ(gene name synonym)|uniprotkb:Olf1/EBF-associated zinc finger protein(gene name synonym)|uniprotkb:Smad- and Olf-interacting zinc finger protein(gene name synonym)|uniprotkb:ZNF423(gene name)|psi-mi:ZNF423(display_short)|uniprotkb:KIAA0760(gene name synonym)|uniprotkb:NPHP14(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267390|imex:IM-17681-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079390.3|dip:DIP-46541N|ensembl:ENSG00000198707(gene)|ensembl:ENST00000552810(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518	go:"GO:0021930"(cerebellar granule cell precursor proliferation)|go:"GO:0021938"(smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q2M1K9|rcsb pdb:2MDG|ensembl:ENSG00000102935(gene)|ensembl:ENST00000561648(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007219"(Notch signaling pathway)|refseq:NP_055884.2|ensembl:ENSP00000455426|ensembl:ENST00000562520|ensembl:ENSP00000457664|ensembl:ENST00000562871|ensembl:ENSP00000457928|refseq:NP_001258549.1|refseq:XP_005255913.1|refseq:XP_016878567.1|refseq:XP_016878566.1	-	-	-	figure legend:Fig. 2F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2012/08/14	2014/10/16	rogid:89HbDVs4UVmzftFFLO/pHklTiUQ9606	rogid:MvDTye6jC364XYE9jlFukJM+fAM9606	intact-crc:187243B9ED1D5651|rigid:7x+NZrJ0g+JbC/7YZUHKTq4klD4	false	sufficient binding region:1917-2479	sufficient binding region:178-406	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O15078	uniprotkb:Q2M1K9	intact:EBI-1811944|uniprotkb:Q1PSK5|uniprotkb:Q66GS8|uniprotkb:Q9H2G6|uniprotkb:Q9H6Q7|uniprotkb:Q9H8I0|ensembl:ENSP00000448012	intact:EBI-950016|intact:EBI-28976649|ensembl:ENSP00000455426|uniprotkb:O94860|uniprotkb:Q9NZ13|uniprotkb:Q76N04	psi-mi:ce290_human(display_long)|uniprotkb:CEP290(gene name)|psi-mi:CEP290(display_short)|uniprotkb:KIAA0373(gene name synonym)|uniprotkb:NPHP6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Tumor antigen se2-2(gene name synonym)|uniprotkb:Cancer/testis antigen 87(gene name synonym)|uniprotkb:BBS14(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein(gene name synonym)	psi-mi:zn423_human(display_long)|uniprotkb:OAZ(gene name synonym)|uniprotkb:Olf1/EBF-associated zinc finger protein(gene name synonym)|uniprotkb:Smad- and Olf-interacting zinc finger protein(gene name synonym)|uniprotkb:ZNF423(gene name)|psi-mi:ZNF423(display_short)|uniprotkb:KIAA0760(gene name synonym)|uniprotkb:NPHP14(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267408|imex:IM-17681-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079390.3|dip:DIP-46541N|ensembl:ENSG00000198707(gene)|ensembl:ENST00000552810(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518	go:"GO:0021930"(cerebellar granule cell precursor proliferation)|go:"GO:0021938"(smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q2M1K9|rcsb pdb:2MDG|ensembl:ENSG00000102935(gene)|ensembl:ENST00000561648(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007219"(Notch signaling pathway)|refseq:NP_055884.2|ensembl:ENSP00000455426|ensembl:ENST00000562520|ensembl:ENSP00000457664|ensembl:ENST00000562871|ensembl:ENSP00000457928|refseq:NP_001258549.1|refseq:XP_005255913.1|refseq:XP_016878567.1|refseq:XP_016878566.1	-	-	-	figure legend:Fig. 2F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2012/08/14	2014/10/16	rogid:89HbDVs4UVmzftFFLO/pHklTiUQ9606	rogid:MvDTye6jC364XYE9jlFukJM+fAM9606	intact-crc:DD91A257166EC462|rigid:7x+NZrJ0g+JbC/7YZUHKTq4klD4	false	sufficient binding region:1917-2479	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q86SQ7	uniprotkb:Q01130	intact:EBI-1047850|uniprotkb:Q3ZCR6|uniprotkb:Q8N5F2|uniprotkb:Q9P0F1|uniprotkb:O60527|ensembl:ENSP00000355499|ensembl:ENSP00000483550	intact:EBI-627047|uniprotkb:B3KWD5|ensembl:ENSP00000353089|ensembl:ENSP00000376276|ensembl:ENSP00000391278|ensembl:ENSP00000462425|uniprotkb:B4DN89|uniprotkb:H0YG49	psi-mi:sdcg8_human(display_long)|uniprotkb:Antigen NY-CO-8(gene name synonym)|uniprotkb:Centrosomal colon cancer autoantigen protein(gene name synonym)|uniprotkb:SDCCAG8(gene name)|psi-mi:SDCCAG8(display_short)|uniprotkb:CCCAP(gene name synonym)|uniprotkb:NPHP10(gene name synonym)|uniprotkb:HSPC085(orf name)	psi-mi:srsf2_human(display_long)|uniprotkb:Splicing factor SC35(gene name synonym)|uniprotkb:Splicing component, 35 kDa(gene name synonym)|uniprotkb:Protein PR264(gene name synonym)|uniprotkb:SRSF2(gene name)|psi-mi:SRSF2(display_short)|uniprotkb:SFRS2(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 2(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267445|imex:IM-17681-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006633.1|ensembl:ENSG00000054282(gene)|ensembl:ENSG00000276111(gene)|ensembl:ENST00000366541(transcript)|ensembl:ENST00000622598(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030030"(cell projection organization)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035148"(tube formation)|go:"GO:0036064"(ciliary basal body)|go:"GO:0097733"(photoreceptor cell cilium)|go:"GO:1902017"(regulation of cilium assembly)|interpro:IPR031887|mint:Q86SQ7|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:XP_005273080.1	ensembl:ENSG00000161547(gene)|ensembl:ENST00000359995(transcript)|ensembl:ENST00000392485(transcript)|ensembl:ENST00000452355(transcript)|ensembl:ENST00000585202(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035061"(interchromatin granule)|go:"GO:0036002"(pre-mRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034893|interpro:IPR035979|mint:Q01130|rcsb pdb:2KN4|rcsb pdb:2LEA|rcsb pdb:2LEB|rcsb pdb:2LEC|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0003723"(RNA binding)|refseq:NP_001182356.1|refseq:NP_003007.2|refseq:XP_016880431.1|dip:DIP-33836N	-	-	-	figure legend:Fig. 4B-C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line)	-	2012/08/14	2014/10/16	rogid:Z3ynDtbmAV7usLzKH+M3Ilf6Ebw9606	rogid:/LUrJ8xa42APUsgH5ke590Kxsh89606	intact-crc:D0EB121BAD5FF88F|rigid:2xtpQTHXgF9+qV5SAI7/vRK5wWo	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q01130	uniprotkb:Q9UPV0	intact:EBI-627047|uniprotkb:B3KWD5|ensembl:ENSP00000353089|ensembl:ENSP00000376276|ensembl:ENSP00000391278|ensembl:ENSP00000462425|uniprotkb:B4DN89|uniprotkb:H0YG49	intact:EBI-3937015|uniprotkb:Q9UFJ6|uniprotkb:Q9NVS0|uniprotkb:Q6PKH9|uniprotkb:Q7Z2X9|ensembl:ENSP00000278935	psi-mi:srsf2_human(display_long)|uniprotkb:Splicing factor SC35(gene name synonym)|uniprotkb:Splicing component, 35 kDa(gene name synonym)|uniprotkb:Protein PR264(gene name synonym)|uniprotkb:SRSF2(gene name)|psi-mi:SRSF2(display_short)|uniprotkb:SFRS2(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 2(gene name synonym)	psi-mi:ce164_human(display_long)|uniprotkb:CEP164(gene name)|psi-mi:CEP164(display_short)|uniprotkb:KIAA1052(gene name synonym)|uniprotkb:NPHP15(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267454|imex:IM-17681-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000161547(gene)|ensembl:ENST00000359995(transcript)|ensembl:ENST00000392485(transcript)|ensembl:ENST00000452355(transcript)|ensembl:ENST00000585202(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035061"(interchromatin granule)|go:"GO:0036002"(pre-mRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034893|interpro:IPR035979|mint:Q01130|rcsb pdb:2KN4|rcsb pdb:2LEA|rcsb pdb:2LEB|rcsb pdb:2LEC|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0003723"(RNA binding)|refseq:NP_001182356.1|refseq:NP_003007.2|refseq:XP_016880431.1|dip:DIP-33836N	ensembl:ENSG00000110274(gene)|ensembl:ENST00000278935(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055771.4|refseq:NP_001258862.1|refseq:XP_005271513.1|refseq:XP_005271514.1	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 4E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line)	-	2012/08/14	2014/10/16	rogid:/LUrJ8xa42APUsgH5ke590Kxsh89606	rogid:2KpJEO+xb35LM5rSOk1vGZTZ6Zc9606	intact-crc:74F0060ADDEA7EA7|rigid:0Kxi2L5iIVJ7zqjTJI8sWIr4RhM	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q86SQ7	uniprotkb:Q9UPV0	intact:EBI-1047850|uniprotkb:Q3ZCR6|uniprotkb:Q8N5F2|uniprotkb:Q9P0F1|uniprotkb:O60527|ensembl:ENSP00000355499|ensembl:ENSP00000483550	intact:EBI-3937015|uniprotkb:Q9UFJ6|uniprotkb:Q9NVS0|uniprotkb:Q6PKH9|uniprotkb:Q7Z2X9|ensembl:ENSP00000278935	psi-mi:sdcg8_human(display_long)|uniprotkb:Antigen NY-CO-8(gene name synonym)|uniprotkb:Centrosomal colon cancer autoantigen protein(gene name synonym)|uniprotkb:SDCCAG8(gene name)|psi-mi:SDCCAG8(display_short)|uniprotkb:CCCAP(gene name synonym)|uniprotkb:NPHP10(gene name synonym)|uniprotkb:HSPC085(orf name)	psi-mi:ce164_human(display_long)|uniprotkb:CEP164(gene name)|psi-mi:CEP164(display_short)|uniprotkb:KIAA1052(gene name synonym)|uniprotkb:NPHP15(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267459|imex:IM-17681-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006633.1|ensembl:ENSG00000054282(gene)|ensembl:ENSG00000276111(gene)|ensembl:ENST00000366541(transcript)|ensembl:ENST00000622598(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030030"(cell projection organization)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035148"(tube formation)|go:"GO:0036064"(ciliary basal body)|go:"GO:0097733"(photoreceptor cell cilium)|go:"GO:1902017"(regulation of cilium assembly)|interpro:IPR031887|mint:Q86SQ7|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:XP_005273080.1	ensembl:ENSG00000110274(gene)|ensembl:ENST00000278935(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055771.4|refseq:NP_001258862.1|refseq:XP_005271513.1|refseq:XP_005271514.1	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 4G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line)	-	2012/08/14	2014/10/16	rogid:Z3ynDtbmAV7usLzKH+M3Ilf6Ebw9606	rogid:2KpJEO+xb35LM5rSOk1vGZTZ6Zc9606	intact-crc:7ADFA80F7DA27007|rigid:58TmnPkdPRiBoYYha1MNuUZl9Jw	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q2M1K9	uniprotkb:Q01130	intact:EBI-950016|intact:EBI-28976649|ensembl:ENSP00000455426|uniprotkb:O94860|uniprotkb:Q9NZ13|uniprotkb:Q76N04	intact:EBI-627047|uniprotkb:B3KWD5|ensembl:ENSP00000353089|ensembl:ENSP00000376276|ensembl:ENSP00000391278|ensembl:ENSP00000462425|uniprotkb:B4DN89|uniprotkb:H0YG49	psi-mi:zn423_human(display_long)|uniprotkb:OAZ(gene name synonym)|uniprotkb:Olf1/EBF-associated zinc finger protein(gene name synonym)|uniprotkb:Smad- and Olf-interacting zinc finger protein(gene name synonym)|uniprotkb:ZNF423(gene name)|psi-mi:ZNF423(display_short)|uniprotkb:KIAA0760(gene name synonym)|uniprotkb:NPHP14(gene name synonym)	psi-mi:srsf2_human(display_long)|uniprotkb:Splicing factor SC35(gene name synonym)|uniprotkb:Splicing component, 35 kDa(gene name synonym)|uniprotkb:Protein PR264(gene name synonym)|uniprotkb:SRSF2(gene name)|psi-mi:SRSF2(display_short)|uniprotkb:SFRS2(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 2(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267449|imex:IM-17681-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0021930"(cerebellar granule cell precursor proliferation)|go:"GO:0021938"(smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q2M1K9|rcsb pdb:2MDG|ensembl:ENSG00000102935(gene)|ensembl:ENST00000561648(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007219"(Notch signaling pathway)|refseq:NP_055884.2|ensembl:ENSP00000455426|ensembl:ENST00000562520|ensembl:ENSP00000457664|ensembl:ENST00000562871|ensembl:ENSP00000457928|refseq:NP_001258549.1|refseq:XP_005255913.1|refseq:XP_016878567.1|refseq:XP_016878566.1	ensembl:ENSG00000161547(gene)|ensembl:ENST00000359995(transcript)|ensembl:ENST00000392485(transcript)|ensembl:ENST00000452355(transcript)|ensembl:ENST00000585202(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035061"(interchromatin granule)|go:"GO:0036002"(pre-mRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034893|interpro:IPR035979|mint:Q01130|rcsb pdb:2KN4|rcsb pdb:2LEA|rcsb pdb:2LEB|rcsb pdb:2LEC|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0003723"(RNA binding)|refseq:NP_001182356.1|refseq:NP_003007.2|refseq:XP_016880431.1|dip:DIP-33836N	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line)	-	2012/08/14	2014/10/16	rogid:MvDTye6jC364XYE9jlFukJM+fAM9606	rogid:/LUrJ8xa42APUsgH5ke590Kxsh89606	intact-crc:6908B430159314AF|rigid:OrxrGWR0McYol+rp74L6zJ8X4AQ	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q01130	uniprotkb:O14757	intact:EBI-627047|uniprotkb:B3KWD5|ensembl:ENSP00000353089|ensembl:ENSP00000376276|ensembl:ENSP00000391278|ensembl:ENSP00000462425|uniprotkb:B4DN89|uniprotkb:H0YG49	intact:EBI-974488|ensembl:ENSP00000388648|ensembl:ENSP00000412504|ensembl:ENSP00000432890|ensembl:ENSP00000435371|ensembl:ENSP00000481616|uniprotkb:B4DDD0|uniprotkb:F5H7S4|uniprotkb:A8K934|uniprotkb:B4DSK3|uniprotkb:B5BTY6|uniprotkb:H2BI51	psi-mi:srsf2_human(display_long)|uniprotkb:Splicing factor SC35(gene name synonym)|uniprotkb:Splicing component, 35 kDa(gene name synonym)|uniprotkb:Protein PR264(gene name synonym)|uniprotkb:SRSF2(gene name)|psi-mi:SRSF2(display_short)|uniprotkb:SFRS2(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 2(gene name synonym)	psi-mi:chk1_human(display_long)|uniprotkb:CHEK1(gene name)|psi-mi:CHEK1(display_short)|uniprotkb:CHK1(gene name synonym)|uniprotkb:CHK1 checkpoint homolog(gene name synonym)|uniprotkb:Checkpoint kinase-1(gene name synonym)|uniprotkb:Cell cycle checkpoint kinase(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267469|imex:IM-17681-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000161547(gene)|ensembl:ENST00000359995(transcript)|ensembl:ENST00000392485(transcript)|ensembl:ENST00000452355(transcript)|ensembl:ENST00000585202(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035061"(interchromatin granule)|go:"GO:0036002"(pre-mRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034893|interpro:IPR035979|mint:Q01130|rcsb pdb:2KN4|rcsb pdb:2LEA|rcsb pdb:2LEB|rcsb pdb:2LEC|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0003723"(RNA binding)|refseq:NP_001182356.1|refseq:NP_003007.2|refseq:XP_016880431.1|dip:DIP-33836N	ensembl:ENSG00000149554(gene)|ensembl:ENST00000428830(transcript)|ensembl:ENST00000438015(transcript)|ensembl:ENST00000524737(transcript)|ensembl:ENST00000532449(transcript)|ensembl:ENST00000534070(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010767"(regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035402"("histone kinase activity (H3-T11 specific)")|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045839"(negative regulation of mitotic nuclear division)|go:"GO:0046602"(regulation of mitotic centrosome separation)|go:"GO:0048096"|go:"GO:0070317"(negative regulation of G0 to G1 transition)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090399"(replicative senescence)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902742"(apoptotic process involved in development)|go:"GO:2000615"(regulation of histone H3-K9 acetylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR034670|mint:O14757|rcsb pdb:1IA8|rcsb pdb:1NVQ|rcsb pdb:1NVR|rcsb pdb:1NVS|rcsb pdb:1ZLT|rcsb pdb:1ZYS|rcsb pdb:2AYP|rcsb pdb:2BR1|rcsb pdb:2BRB|rcsb pdb:2BRG|rcsb pdb:2BRH|rcsb pdb:2BRM|rcsb pdb:2BRN|rcsb pdb:2BRO|rcsb pdb:2C3J|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|rcsb pdb:2C3K|rcsb pdb:2C3L|rcsb pdb:2CGU|rcsb pdb:2CGV|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0006997"(nucleus organization)|rcsb pdb:2CGX|rcsb pdb:2E9N|rcsb pdb:2E9O|rcsb pdb:2E9P|rcsb pdb:2E9U|rcsb pdb:2E9V|rcsb pdb:2GDO|rcsb pdb:2GHG|rcsb pdb:2HOG|rcsb pdb:2HXL|rcsb pdb:2HXQ|rcsb pdb:2CGW|rcsb pdb:2HY0|rcsb pdb:2QHM|rcsb pdb:2QHN|rcsb pdb:2R0U|rcsb pdb:2WMQ|rcsb pdb:2WMR|rcsb pdb:2WMS|rcsb pdb:2WMT|rcsb pdb:2WMU|rcsb pdb:2YM7|rcsb pdb:2YM8|rcsb pdb:2YWP|rcsb pdb:3F9N|rcsb pdb:3JVR|rcsb pdb:3JVS|rcsb pdb:3NLB|rcsb pdb:3OT3|rcsb pdb:3OT8|rcsb pdb:3PA3|rcsb pdb:3PA4|rcsb pdb:2WMV|rcsb pdb:3PA5|rcsb pdb:3TKH|rcsb pdb:3TKI|rcsb pdb:2WMW|rcsb pdb:3U9N|rcsb pdb:4FSM|rcsb pdb:4FSN|rcsb pdb:2WMX|rcsb pdb:4FSQ|rcsb pdb:2X8D|rcsb pdb:2X8E|rcsb pdb:4FSR|rcsb pdb:4FST|rcsb pdb:4FSU|rcsb pdb:4FSW|rcsb pdb:4FSY|rcsb pdb:2X8I|rcsb pdb:2XEY|rcsb pdb:2XEZ|rcsb pdb:2XF0|rcsb pdb:2YDI|rcsb pdb:2YDJ|rcsb pdb:2YDK|rcsb pdb:2YER|rcsb pdb:2YEX|rcsb pdb:2YM3|rcsb pdb:2YM4|rcsb pdb:2YM5|rcsb pdb:2YM6|rcsb pdb:4FSZ|rcsb pdb:4FT0|rcsb pdb:4FT3|rcsb pdb:4FT5|rcsb pdb:4FT7|rcsb pdb:4FTA|rcsb pdb:4FTC|rcsb pdb:4FTI|rcsb pdb:4FTJ|rcsb pdb:4FTK|rcsb pdb:4FTL|rcsb pdb:4FTM|rcsb pdb:4FTN|rcsb pdb:4FTO|rcsb pdb:4FTQ|rcsb pdb:4FTR|rcsb pdb:4FTT|rcsb pdb:4FTU|rcsb pdb:4GH2|rcsb pdb:4FT9|rcsb pdb:4HYH|rcsb pdb:4HYI|rcsb pdb:4JIK|rcsb pdb:4QYE|rcsb pdb:4QYF|rcsb pdb:4QYG|rcsb pdb:4QYH|rcsb pdb:4RVK|rcsb pdb:4RVL|rcsb pdb:4RVM|rcsb pdb:5DLS|rcsb pdb:5F4N|rcsb pdb:5OOP|rcsb pdb:5OOR|rcsb pdb:5OOT|rcsb pdb:5OP2|rcsb pdb:5OP4|rcsb pdb:5OP5|rcsb pdb:5OP7|rcsb pdb:5OPB|rcsb pdb:5OPR|rcsb pdb:5OPS|rcsb pdb:5OPU|rcsb pdb:5OPV|rcsb pdb:5OQ5|rcsb pdb:5OQ6|rcsb pdb:5OQ7|rcsb pdb:5OQ8|rcsb pdb:5WI2|rcsb pdb:6FC8|rcsb pdb:6FCF|rcsb pdb:6FCK|rcsb pdb:7AKM|rcsb pdb:7AKO|rcsb pdb:7MCK|reactome:R-HSA-1433557|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-69601|reactome:R-HSA-75035|reactome:R-HSA-8953750|reactome:R-HSA-176187|refseq:NP_001107593.1|refseq:NP_001107594.1|refseq:NP_001265.2|refseq:NP_001231775.1|refseq:XP_016872635.1|refseq:NP_001317357.1|dip:DIP-24182N	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 4J|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line)	-	2012/08/14	2014/10/16	rogid:/LUrJ8xa42APUsgH5ke590Kxsh89606	rogid:S6QMFtpTWlBPrg6GN6b/1pgFCg09606	intact-crc:5F86814AF4C0DE10|rigid:LI3YCcYWQ7uHcAmTaP0nS5Jcj4k	false	-	O-phospho-L-serine:317-317	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q86SQ7	uniprotkb:Q2M1K9	intact:EBI-1047850|uniprotkb:Q3ZCR6|uniprotkb:Q8N5F2|uniprotkb:Q9P0F1|uniprotkb:O60527|ensembl:ENSP00000355499|ensembl:ENSP00000483550	intact:EBI-950016|intact:EBI-28976649|ensembl:ENSP00000455426|uniprotkb:O94860|uniprotkb:Q9NZ13|uniprotkb:Q76N04	psi-mi:sdcg8_human(display_long)|uniprotkb:Antigen NY-CO-8(gene name synonym)|uniprotkb:Centrosomal colon cancer autoantigen protein(gene name synonym)|uniprotkb:SDCCAG8(gene name)|psi-mi:SDCCAG8(display_short)|uniprotkb:CCCAP(gene name synonym)|uniprotkb:NPHP10(gene name synonym)|uniprotkb:HSPC085(orf name)	psi-mi:zn423_human(display_long)|uniprotkb:OAZ(gene name synonym)|uniprotkb:Olf1/EBF-associated zinc finger protein(gene name synonym)|uniprotkb:Smad- and Olf-interacting zinc finger protein(gene name synonym)|uniprotkb:ZNF423(gene name)|psi-mi:ZNF423(display_short)|uniprotkb:KIAA0760(gene name synonym)|uniprotkb:NPHP14(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267464|imex:IM-17681-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006633.1|ensembl:ENSG00000054282(gene)|ensembl:ENSG00000276111(gene)|ensembl:ENST00000366541(transcript)|ensembl:ENST00000622598(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030030"(cell projection organization)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035148"(tube formation)|go:"GO:0036064"(ciliary basal body)|go:"GO:0097733"(photoreceptor cell cilium)|go:"GO:1902017"(regulation of cilium assembly)|interpro:IPR031887|mint:Q86SQ7|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:XP_005273080.1	go:"GO:0021930"(cerebellar granule cell precursor proliferation)|go:"GO:0021938"(smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q2M1K9|rcsb pdb:2MDG|ensembl:ENSG00000102935(gene)|ensembl:ENST00000561648(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007219"(Notch signaling pathway)|refseq:NP_055884.2|ensembl:ENSP00000455426|ensembl:ENST00000562520|ensembl:ENSP00000457664|ensembl:ENST00000562871|ensembl:ENSP00000457928|refseq:NP_001258549.1|refseq:XP_005255913.1|refseq:XP_016878567.1|refseq:XP_016878566.1	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 4F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line)	-	2012/08/14	2014/10/16	rogid:Z3ynDtbmAV7usLzKH+M3Ilf6Ebw9606	rogid:MvDTye6jC364XYE9jlFukJM+fAM9606	intact-crc:91F1919810E8EABC|rigid:12o0VMyYuPA9k9Sl+xGK6zK9Qro	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q9UPV0	uniprotkb:Q53HC0	intact:EBI-3937015|uniprotkb:Q9UFJ6|uniprotkb:Q9NVS0|uniprotkb:Q6PKH9|uniprotkb:Q7Z2X9|ensembl:ENSP00000278935	intact:EBI-719994|uniprotkb:Q9H697|uniprotkb:B3KNQ0|ensembl:ENSP00000238156|ensembl:ENSP00000488830	psi-mi:ce164_human(display_long)|uniprotkb:CEP164(gene name)|psi-mi:CEP164(display_short)|uniprotkb:KIAA1052(gene name synonym)|uniprotkb:NPHP15(gene name synonym)	psi-mi:ccd92_human(display_long)|uniprotkb:Limkain beta-2(gene name synonym)|uniprotkb:CCDC92(gene name)|psi-mi:CCDC92(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267726|imex:IM-17681-24	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110274(gene)|ensembl:ENST00000278935(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055771.4|refseq:NP_001258862.1|refseq:XP_005271513.1|refseq:XP_005271514.1	refseq:NP_079416.1|ensembl:ENSG00000119242(gene)|ensembl:ENSG00000275035(gene)|ensembl:ENST00000238156(transcript)|ensembl:ENST00000632401(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033224|interpro:IPR039496|interpro:IPR040370|mint:Q53HC0|refseq:NP_001291886.1|refseq:NP_001291887.1|refseq:NP_001291888.1|refseq:NP_001291889.1|refseq:NP_001291890.1|refseq:XP_005253681.1|refseq:XP_016875473.1	go:"GO:0005814"(centriole)	-	-	figure legend:Supp Fig. 5I|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line)	-	2012/08/14	2014/10/16	rogid:2KpJEO+xb35LM5rSOk1vGZTZ6Zc9606	rogid:Iu/FzTqEpzn8N5WUTt1OwoKWxyc9606	intact-crc:088808AED4A36074|rigid:EkdMs4j2ZNXniaX4a2O7FHpzFZw	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q92997	uniprotkb:Q9UPV0	intact:EBI-739789|uniprotkb:O14642|uniprotkb:Q13531|uniprotkb:Q8N5E9|uniprotkb:Q92607|uniprotkb:D3DNT0|intact:EBI-11081380|uniprotkb:B4E3E5|ensembl:ENSP00000316054	intact:EBI-3937015|uniprotkb:Q9UFJ6|uniprotkb:Q9NVS0|uniprotkb:Q6PKH9|uniprotkb:Q7Z2X9|ensembl:ENSP00000278935	psi-mi:dvl3_human(display_long)|uniprotkb:DVL3(gene name)|psi-mi:DVL3(display_short)|uniprotkb:KIAA0208(gene name synonym)|uniprotkb:DSH homolog 3(gene name synonym)	psi-mi:ce164_human(display_long)|uniprotkb:CEP164(gene name)|psi-mi:CEP164(display_short)|uniprotkb:KIAA1052(gene name synonym)|uniprotkb:NPHP15(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267780|imex:IM-17681-30	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004414.3|dip:DIP-34509N|ensembl:ENSG00000161202(gene)|ensembl:ENST00000313143(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0042493"|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q92997|rcsb pdb:6V7O|rcsb pdb:6ZC6|rcsb pdb:6ZC8|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-4086400|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-9673324	ensembl:ENSG00000110274(gene)|ensembl:ENST00000278935(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055771.4|refseq:NP_001258862.1|refseq:XP_005271513.1|refseq:XP_005271514.1	-	-	-	figure legend:Supp. Fig. 6F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/08/14	2014/10/16	rogid:yJ3YIp5IhvKTQwa3bK5yTjNyqXk9606	rogid:2KpJEO+xb35LM5rSOk1vGZTZ6Zc9606	intact-crc:D31F5F601EA49B0A|rigid:6Eou6L6f3WhSUV45QrBSv29ZbbE	false	-	glutathione s tranferase tag:?-?|sufficient binding region:1-164(IPR001202)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O15078	uniprotkb:Q2M1K9	intact:EBI-1811944|uniprotkb:Q1PSK5|uniprotkb:Q66GS8|uniprotkb:Q9H2G6|uniprotkb:Q9H6Q7|uniprotkb:Q9H8I0|ensembl:ENSP00000448012	intact:EBI-950016|intact:EBI-28976649|ensembl:ENSP00000455426|uniprotkb:O94860|uniprotkb:Q9NZ13|uniprotkb:Q76N04	psi-mi:ce290_human(display_long)|uniprotkb:CEP290(gene name)|psi-mi:CEP290(display_short)|uniprotkb:KIAA0373(gene name synonym)|uniprotkb:NPHP6(gene name synonym)|uniprotkb:Nephrocystin-6(gene name synonym)|uniprotkb:Tumor antigen se2-2(gene name synonym)|uniprotkb:Cancer/testis antigen 87(gene name synonym)|uniprotkb:BBS14(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 14 protein(gene name synonym)	psi-mi:zn423_human(display_long)|uniprotkb:OAZ(gene name synonym)|uniprotkb:Olf1/EBF-associated zinc finger protein(gene name synonym)|uniprotkb:Smad- and Olf-interacting zinc finger protein(gene name synonym)|uniprotkb:ZNF423(gene name)|psi-mi:ZNF423(display_short)|uniprotkb:KIAA0760(gene name synonym)|uniprotkb:NPHP14(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267426|imex:IM-17681-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079390.3|dip:DIP-46541N|ensembl:ENSG00000198707(gene)|ensembl:ENST00000552810(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030902"(hindbrain development)|go:"GO:0030916"(otic vesicle formation)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048793"(pronephros development)|go:"GO:0060271"(cilium assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|go:"GO:1905349"(ciliary transition zone assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR026201|interpro:IPR032321|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518	go:"GO:0021930"(cerebellar granule cell precursor proliferation)|go:"GO:0021938"(smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q2M1K9|rcsb pdb:2MDG|ensembl:ENSG00000102935(gene)|ensembl:ENST00000561648(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007219"(Notch signaling pathway)|refseq:NP_055884.2|ensembl:ENSP00000455426|ensembl:ENST00000562520|ensembl:ENSP00000457664|ensembl:ENST00000562871|ensembl:ENSP00000457928|refseq:NP_001258549.1|refseq:XP_005255913.1|refseq:XP_016878567.1|refseq:XP_016878566.1	-	-	-	figure legend:Fig. 2G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/08/14	2014/10/16	rogid:89HbDVs4UVmzftFFLO/pHklTiUQ9606	rogid:MvDTye6jC364XYE9jlFukJM+fAM9606	intact-crc:1BEA5A18A85A740D|rigid:7x+NZrJ0g+JbC/7YZUHKTq4klD4	false	v5 tag:?-?|sufficient binding region:1917-2479	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9UPV0	uniprotkb:Q92997	intact:EBI-3937015|uniprotkb:Q9UFJ6|uniprotkb:Q9NVS0|uniprotkb:Q6PKH9|uniprotkb:Q7Z2X9|ensembl:ENSP00000278935	intact:EBI-739789|uniprotkb:O14642|uniprotkb:Q13531|uniprotkb:Q8N5E9|uniprotkb:Q92607|uniprotkb:D3DNT0|intact:EBI-11081380|uniprotkb:B4E3E5|ensembl:ENSP00000316054	psi-mi:ce164_human(display_long)|uniprotkb:CEP164(gene name)|psi-mi:CEP164(display_short)|uniprotkb:KIAA1052(gene name synonym)|uniprotkb:NPHP15(gene name synonym)	psi-mi:dvl3_human(display_long)|uniprotkb:DVL3(gene name)|psi-mi:DVL3(display_short)|uniprotkb:KIAA0208(gene name synonym)|uniprotkb:DSH homolog 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6284873|imex:IM-17681-32	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110274(gene)|ensembl:ENST00000278935(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055771.4|refseq:NP_001258862.1|refseq:XP_005271513.1|refseq:XP_005271514.1	refseq:NP_004414.3|dip:DIP-34509N|ensembl:ENSG00000161202(gene)|ensembl:ENST00000313143(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0042493"|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q92997|rcsb pdb:6V7O|rcsb pdb:6ZC6|rcsb pdb:6ZC8|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-4086400|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-9673324	-	-	-	figure legend:Supp. Fig. 6H|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/08/14	2014/10/16	rogid:2KpJEO+xb35LM5rSOk1vGZTZ6Zc9606	rogid:yJ3YIp5IhvKTQwa3bK5yTjNyqXk9606	intact-crc:32DB573B6C6FA880|rigid:6Eou6L6f3WhSUV45QrBSv29ZbbE	false	red fluorescent protein tag:?-?|necessary binding region:525-c	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9UPV0	uniprotkb:Q92997	intact:EBI-3937015|uniprotkb:Q9UFJ6|uniprotkb:Q9NVS0|uniprotkb:Q6PKH9|uniprotkb:Q7Z2X9|ensembl:ENSP00000278935	intact:EBI-739789|uniprotkb:O14642|uniprotkb:Q13531|uniprotkb:Q8N5E9|uniprotkb:Q92607|uniprotkb:D3DNT0|intact:EBI-11081380|uniprotkb:B4E3E5|ensembl:ENSP00000316054	psi-mi:ce164_human(display_long)|uniprotkb:CEP164(gene name)|psi-mi:CEP164(display_short)|uniprotkb:KIAA1052(gene name synonym)|uniprotkb:NPHP15(gene name synonym)	psi-mi:dvl3_human(display_long)|uniprotkb:DVL3(gene name)|psi-mi:DVL3(display_short)|uniprotkb:KIAA0208(gene name synonym)|uniprotkb:DSH homolog 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6284852|imex:IM-17681-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110274(gene)|ensembl:ENST00000278935(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055771.4|refseq:NP_001258862.1|refseq:XP_005271513.1|refseq:XP_005271514.1	refseq:NP_004414.3|dip:DIP-34509N|ensembl:ENSG00000161202(gene)|ensembl:ENST00000313143(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0042493"|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q92997|rcsb pdb:6V7O|rcsb pdb:6ZC6|rcsb pdb:6ZC8|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-4086400|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-9673324	-	-	-	figure legend:Supp. Fig. 6G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/08/14	2014/10/16	rogid:2KpJEO+xb35LM5rSOk1vGZTZ6Zc9606	rogid:yJ3YIp5IhvKTQwa3bK5yTjNyqXk9606	intact-crc:1697094C4C3EF658|rigid:6Eou6L6f3WhSUV45QrBSv29ZbbE	false	green fluorescent protein tag:?-?	necessary binding region:322..322-422..422|flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9UPV0	uniprotkb:Q92997	intact:EBI-3937015|uniprotkb:Q9UFJ6|uniprotkb:Q9NVS0|uniprotkb:Q6PKH9|uniprotkb:Q7Z2X9|ensembl:ENSP00000278935	intact:EBI-739789|uniprotkb:O14642|uniprotkb:Q13531|uniprotkb:Q8N5E9|uniprotkb:Q92607|uniprotkb:D3DNT0|intact:EBI-11081380|uniprotkb:B4E3E5|ensembl:ENSP00000316054	psi-mi:ce164_human(display_long)|uniprotkb:CEP164(gene name)|psi-mi:CEP164(display_short)|uniprotkb:KIAA1052(gene name synonym)|uniprotkb:NPHP15(gene name synonym)	psi-mi:dvl3_human(display_long)|uniprotkb:DVL3(gene name)|psi-mi:DVL3(display_short)|uniprotkb:KIAA0208(gene name synonym)|uniprotkb:DSH homolog 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6284885|imex:IM-17681-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110274(gene)|ensembl:ENST00000278935(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055771.4|refseq:NP_001258862.1|refseq:XP_005271513.1|refseq:XP_005271514.1	refseq:NP_004414.3|dip:DIP-34509N|ensembl:ENSG00000161202(gene)|ensembl:ENST00000313143(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0042493"|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q92997|rcsb pdb:6V7O|rcsb pdb:6ZC6|rcsb pdb:6ZC8|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-4086400|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-9673324	-	-	-	figure legend:Supp. Fig. 6H|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/08/14	2014/10/16	rogid:2KpJEO+xb35LM5rSOk1vGZTZ6Zc9606	rogid:yJ3YIp5IhvKTQwa3bK5yTjNyqXk9606	intact-crc:1F6F45F5568EB6B2|rigid:6Eou6L6f3WhSUV45QrBSv29ZbbE	false	necessary binding region:525-1460|red fluorescent protein tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9UPV0	uniprotkb:Q7Z494	intact:EBI-3937015|uniprotkb:Q9UFJ6|uniprotkb:Q9NVS0|uniprotkb:Q6PKH9|uniprotkb:Q7Z2X9|ensembl:ENSP00000278935	intact:EBI-2804263|uniprotkb:Q68D99|uniprotkb:Q8NCM5|uniprotkb:Q7Z493|uniprotkb:Q5JPE3|uniprotkb:Q96NK2|uniprotkb:Q5JPE6|uniprotkb:Q6NVH3|uniprotkb:Q96N70|uniprotkb:Q7Z492|uniprotkb:Q8N9R2|ensembl:ENSP00000338766	psi-mi:ce164_human(display_long)|uniprotkb:CEP164(gene name)|psi-mi:CEP164(display_short)|uniprotkb:KIAA1052(gene name synonym)|uniprotkb:NPHP15(gene name synonym)	psi-mi:nphp3_human(display_long)|uniprotkb:KIAA2000(gene name synonym)|uniprotkb:NPHP3(gene name)|psi-mi:NPHP3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267743|imex:IM-17681-26	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110274(gene)|ensembl:ENST00000278935(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055771.4|refseq:NP_001258862.1|refseq:XP_005271513.1|refseq:XP_005271514.1	refseq:NP_694972.3|ensembl:ENSG00000113971(gene)|ensembl:ENST00000337331(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001947"(heart looping)|go:"GO:0003283"(atrial septum development)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030324"(lung development)|go:"GO:0035469"(determination of pancreatic left/right asymmetry)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060027"(convergent extension involved in gastrulation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060287"(epithelial cilium movement involved in determination of left/right asymmetry)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0071908"(determination of intestine left/right asymmetry)|go:"GO:0071909"(determination of stomach left/right asymmetry)|go:"GO:0071910"(determination of liver left/right asymmetry)|go:"GO:0072189"(ureter development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000167"(regulation of planar cell polarity pathway involved in neural tube closure)|rcsb pdb:5L7K|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027417|reactome:R-HSA-5624138	-	-	-	figure legend:Supp. Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/08/14	2014/10/16	rogid:2KpJEO+xb35LM5rSOk1vGZTZ6Zc9606	rogid:7SitCJ9bwhu4VXh9FjX/wWCq0UQ9606	intact-crc:7B5CCA41E02FFBBB|rigid:CFdYqovO2iafIOLDEM2fTpLrz/0	false	v5 tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q7Z494	uniprotkb:Q9UPV0	intact:EBI-2804263|uniprotkb:Q68D99|uniprotkb:Q8NCM5|uniprotkb:Q7Z493|uniprotkb:Q5JPE3|uniprotkb:Q96NK2|uniprotkb:Q5JPE6|uniprotkb:Q6NVH3|uniprotkb:Q96N70|uniprotkb:Q7Z492|uniprotkb:Q8N9R2|ensembl:ENSP00000338766	intact:EBI-3937015|uniprotkb:Q9UFJ6|uniprotkb:Q9NVS0|uniprotkb:Q6PKH9|uniprotkb:Q7Z2X9|ensembl:ENSP00000278935	psi-mi:nphp3_human(display_long)|uniprotkb:KIAA2000(gene name synonym)|uniprotkb:NPHP3(gene name)|psi-mi:NPHP3(display_short)	psi-mi:ce164_human(display_long)|uniprotkb:CEP164(gene name)|psi-mi:CEP164(display_short)|uniprotkb:KIAA1052(gene name synonym)|uniprotkb:NPHP15(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267735|imex:IM-17681-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_694972.3|ensembl:ENSG00000113971(gene)|ensembl:ENST00000337331(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001947"(heart looping)|go:"GO:0003283"(atrial septum development)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030324"(lung development)|go:"GO:0035469"(determination of pancreatic left/right asymmetry)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0060027"(convergent extension involved in gastrulation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060287"(epithelial cilium movement involved in determination of left/right asymmetry)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0071908"(determination of intestine left/right asymmetry)|go:"GO:0071909"(determination of stomach left/right asymmetry)|go:"GO:0071910"(determination of liver left/right asymmetry)|go:"GO:0072189"(ureter development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000095"(regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000167"(regulation of planar cell polarity pathway involved in neural tube closure)|rcsb pdb:5L7K|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027417|reactome:R-HSA-5624138	ensembl:ENSG00000110274(gene)|ensembl:ENST00000278935(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055771.4|refseq:NP_001258862.1|refseq:XP_005271513.1|refseq:XP_005271514.1	-	-	-	figure legend:Supp. Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/08/14	2014/10/16	rogid:7SitCJ9bwhu4VXh9FjX/wWCq0UQ9606	rogid:2KpJEO+xb35LM5rSOk1vGZTZ6Zc9606	intact-crc:E872C2E0320E3D67|rigid:CFdYqovO2iafIOLDEM2fTpLrz/0	false	v5 tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q53HC0	uniprotkb:Q9UPV0	intact:EBI-719994|uniprotkb:Q9H697|uniprotkb:B3KNQ0|ensembl:ENSP00000238156|ensembl:ENSP00000488830	intact:EBI-3937015|uniprotkb:Q9UFJ6|uniprotkb:Q9NVS0|uniprotkb:Q6PKH9|uniprotkb:Q7Z2X9|ensembl:ENSP00000278935	psi-mi:ccd92_human(display_long)|uniprotkb:Limkain beta-2(gene name synonym)|uniprotkb:CCDC92(gene name)|psi-mi:CCDC92(display_short)	psi-mi:ce164_human(display_long)|uniprotkb:CEP164(gene name)|psi-mi:CEP164(display_short)|uniprotkb:KIAA1052(gene name synonym)|uniprotkb:NPHP15(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267552|imex:IM-17681-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079416.1|ensembl:ENSG00000119242(gene)|ensembl:ENSG00000275035(gene)|ensembl:ENST00000238156(transcript)|ensembl:ENST00000632401(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033224|interpro:IPR039496|interpro:IPR040370|mint:Q53HC0|refseq:NP_001291886.1|refseq:NP_001291887.1|refseq:NP_001291888.1|refseq:NP_001291889.1|refseq:NP_001291890.1|refseq:XP_005253681.1|refseq:XP_016875473.1	ensembl:ENSG00000110274(gene)|ensembl:ENST00000278935(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055771.4|refseq:NP_001258862.1|refseq:XP_005271513.1|refseq:XP_005271514.1	-	-	-	figure legend:Supp Fig. 5C|caution:Binding region length is given as 1101-1640 in the text. As the known length of the protein is 1460, it has been assumed that two digits have been reversed.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2012/08/14	2014/10/16	rogid:Iu/FzTqEpzn8N5WUTt1OwoKWxyc9606	rogid:2KpJEO+xb35LM5rSOk1vGZTZ6Zc9606	intact-crc:43828E1599933CB9|rigid:EkdMs4j2ZNXniaX4a2O7FHpzFZw	false	sufficient binding region:84-274	sufficient binding region:1101-1460|sufficient binding region:1-550	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9UPV0	uniprotkb:Q6IQ55	intact:EBI-3937015|uniprotkb:Q9UFJ6|uniprotkb:Q9NVS0|uniprotkb:Q6PKH9|uniprotkb:Q7Z2X9|ensembl:ENSP00000278935	intact:EBI-1050303|uniprotkb:O94932|uniprotkb:Q6ZN52|uniprotkb:Q8IVV1|ensembl:ENSP00000267890	psi-mi:ce164_human(display_long)|uniprotkb:CEP164(gene name)|psi-mi:CEP164(display_short)|uniprotkb:KIAA1052(gene name synonym)|uniprotkb:NPHP15(gene name synonym)	psi-mi:ttbk2_human(display_long)|uniprotkb:TTBK2(gene name)|psi-mi:TTBK2(display_short)|uniprotkb:KIAA0847(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chaki et al. (2012)	imex:IM-17681|pubmed:22863007	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6267581|imex:IM-17681-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000110274(gene)|ensembl:ENST00000278935(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007049"(cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_055771.4|refseq:NP_001258862.1|refseq:XP_005271513.1|refseq:XP_005271514.1	refseq:NP_775771.3|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019894"(kinesin binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021681"(cerebellar granular layer development)|go:"GO:0021935"(cerebellar granule cell precursor tangential migration)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902817"(negative regulation of protein localization to microtubule)|go:"GO:1904527"(negative regulation of microtubule binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6U0K|rcsb pdb:6VRF|reactome:R-HSA-5620912|ensembl:ENSG00000128881(gene)|ensembl:ENST00000267890(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0004672"(protein kinase activity)	-	-	-	figure legend:Supp Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2012/08/14	2014/10/16	rogid:2KpJEO+xb35LM5rSOk1vGZTZ6Zc9606	rogid:XCTz5pJ+CJnvnlTXQwRM5gW/A389606	intact-crc:A6EF1CF8A6DCE39B|rigid:y09p8EhJ5rod/iy3NpJumDiF87E	false	sufficient binding region:1-550	sufficient binding region:1045-1244	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)