#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P12418 uniprotkb:P07437 intact:EBI-6147319|uniprotkb:A4ZY23|uniprotkb:Q8QT10|uniprotkb:Q71M35 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:mu2_reovd(display_long)|uniprotkb:M1(gene name)|psi-mi:M1(display_short) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10886(reovd)|taxid:10886("Reovirus type 3 (strain Dearing)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154493|imex:IM-17331-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012494(Reovirus minor core protein, Mu-2)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0044163"(host cytoskeleton) refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:R+r+C2QfYpM4TAOjfsS8UPyKKEk10886 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:A6A22E8305BB9F62|rigid:Q9MJXs/hDavwGpme8g3j0y9EdLw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12418 uniprotkb:Q9BQE3 intact:EBI-6147319|uniprotkb:A4ZY23|uniprotkb:Q8QT10|uniprotkb:Q71M35 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:mu2_reovd(display_long)|uniprotkb:M1(gene name)|psi-mi:M1(display_short) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10886(reovd)|taxid:10886("Reovirus type 3 (strain Dearing)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154493|imex:IM-17331-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012494(Reovirus minor core protein, Mu-2)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0044163"(host cytoskeleton) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:R+r+C2QfYpM4TAOjfsS8UPyKKEk10886 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:A6A22E8305BB9F62|rigid:Q9MJXs/hDavwGpme8g3j0y9EdLw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12418 uniprotkb:P62829 intact:EBI-6147319|uniprotkb:A4ZY23|uniprotkb:Q8QT10|uniprotkb:Q71M35 intact:EBI-353303|uniprotkb:P23131|uniprotkb:Q3SWV7|uniprotkb:P24048|uniprotkb:Q29246|uniprotkb:Q6P5S1|ensembl:ENSP00000377865|ensembl:ENSP00000420311 psi-mi:mu2_reovd(display_long)|uniprotkb:M1(gene name)|psi-mi:M1(display_short) psi-mi:rl23_human(display_long)|uniprotkb:RPL23(gene name)|psi-mi:RPL23(display_short)|uniprotkb:60S ribosomal protein L17(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10886(reovd)|taxid:10886("Reovirus type 3 (strain Dearing)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154493|imex:IM-17331-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012494(Reovirus minor core protein, Mu-2)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0044163"(host cytoskeleton) rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|reactome:R-HSA-9010553|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|refseq:NP_000969.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000218(Ribosomal protein L14b/L23e)|interpro:IPR019972|interpro:IPR036853|mint:P62829|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|ensembl:ENSG00000125691(gene)|ensembl:ENST00000394332(transcript)|ensembl:ENST00000479035(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0005730"(nucleolus)|dip:DIP-33156N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:R+r+C2QfYpM4TAOjfsS8UPyKKEk10886 rogid:TiSVU2W4+lkwf12eb4+vG6IFlZA9606 intact-crc:A6A22E8305BB9F62|rigid:Q9MJXs/hDavwGpme8g3j0y9EdLw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12418 uniprotkb:Q96PK6 intact:EBI-6147319|uniprotkb:A4ZY23|uniprotkb:Q8QT10|uniprotkb:Q71M35 intact:EBI-954272|ensembl:ENSP00000311747|uniprotkb:O75932|uniprotkb:Q53GV1|uniprotkb:Q68DQ9|uniprotkb:Q96PK5|uniprotkb:B3KMN4|uniprotkb:Q2PYN1|uniprotkb:D6RGD8|uniprotkb:B0LM41|intact:EBI-16430855|intact:EBI-16472484 psi-mi:mu2_reovd(display_long)|uniprotkb:M1(gene name)|psi-mi:M1(display_short) psi-mi:rbm14_human(display_long)|uniprotkb:RNA-binding motif protein 14(gene name synonym)|uniprotkb:RRM-containing coactivator activator/modulator(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein(gene name synonym)|uniprotkb:RBM14(gene name)|psi-mi:RBM14(display_short)|uniprotkb:SIP(gene name synonym)|uniprotkb:Paraspeckle protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10886(reovd)|taxid:10886("Reovirus type 3 (strain Dearing)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154493|imex:IM-17331-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012494(Reovirus minor core protein, Mu-2)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0044163"(host cytoskeleton) ensembl:ENSG00000239306(gene)|ensembl:ENST00000310137(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009725"(response to hormone)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034506|interpro:IPR034507|go:"GO:0098534"(centriole assembly)|interpro:IPR035979|mint:Q96PK6|rcsb pdb:2DNP|reactome:R-HSA-8941326|refseq:NP_001185765.1|refseq:NP_006319.1|ensembl:ENSP00000311747|ensembl:ENST00000393979|ensembl:ENSP00000377548|ensembl:ENST00000409738|ensembl:ENSP00000386995|refseq:NP_001185766.1|refseq:NP_001185774.1|dip:DIP-50126N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:R+r+C2QfYpM4TAOjfsS8UPyKKEk10886 rogid:Q0UBl2qmfwQTPwUQ7ZDwGIMOYoA9606 intact-crc:A6A22E8305BB9F62|rigid:Q9MJXs/hDavwGpme8g3j0y9EdLw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12418 uniprotkb:P12235 intact:EBI-6147319|uniprotkb:A4ZY23|uniprotkb:Q8QT10|uniprotkb:Q71M35 intact:EBI-359074|uniprotkb:D3DP59|ensembl:ENSP00000281456 psi-mi:mu2_reovd(display_long)|uniprotkb:M1(gene name)|psi-mi:M1(display_short) psi-mi:adt1_human(display_long)|uniprotkb:SLC25A4(gene name)|psi-mi:SLC25A4(display_short)|uniprotkb:ANT1(gene name synonym)|uniprotkb:Adenine nucleotide translocator 1(gene name synonym)|uniprotkb:ADP,ATP carrier protein 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 4(gene name synonym)|uniprotkb:ADP,ATP carrier protein, heart/skeletal muscle isoform T1(gene name synonym)|uniprotkb:AAC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10886(reovd)|taxid:10886("Reovirus type 3 (strain Dearing)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154493|imex:IM-17331-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012494(Reovirus minor core protein, Mu-2)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0044163"(host cytoskeleton) refseq:NP_001142.2|ensembl:ENST00000281456(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0015866"(ADP transport)|ensembl:ENSG00000151729(gene)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12235|reactome:R-HSA-1268020|reactome:R-HSA-180897|reactome:R-HSA-83936|dip:DIP-33116N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:R+r+C2QfYpM4TAOjfsS8UPyKKEk10886 rogid:vs4XIUUUypcIHR9Lz4j1buDAnjM9606 intact-crc:A6A22E8305BB9F62|rigid:Q9MJXs/hDavwGpme8g3j0y9EdLw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12418 uniprotkb:P05141 intact:EBI-6147319|uniprotkb:A4ZY23|uniprotkb:Q8QT10|uniprotkb:Q71M35 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:mu2_reovd(display_long)|uniprotkb:M1(gene name)|psi-mi:M1(display_short) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10886(reovd)|taxid:10886("Reovirus type 3 (strain Dearing)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154493|imex:IM-17331-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012494(Reovirus minor core protein, Mu-2)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0044163"(host cytoskeleton) refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:R+r+C2QfYpM4TAOjfsS8UPyKKEk10886 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:A6A22E8305BB9F62|rigid:Q9MJXs/hDavwGpme8g3j0y9EdLw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12418 uniprotkb:Q8N163 intact:EBI-6147319|uniprotkb:A4ZY23|uniprotkb:Q8QT10|uniprotkb:Q71M35 intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|ensembl:ENSP00000310670|ensembl:ENSP00000373930|uniprotkb:B2RB79|uniprotkb:D3DSR6 psi-mi:mu2_reovd(display_long)|uniprotkb:M1(gene name)|psi-mi:M1(display_short) psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10886(reovd)|taxid:10886("Reovirus type 3 (strain Dearing)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154493|imex:IM-17331-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012494(Reovirus minor core protein, Mu-2)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0044163"(host cytoskeleton) refseq:NP_066997.3|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|interpro:IPR028811|mint:Q8N163|reactome:R-HSA-3371453|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|dip:DIP-38122N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:R+r+C2QfYpM4TAOjfsS8UPyKKEk10886 rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606 intact-crc:A6A22E8305BB9F62|rigid:Q9MJXs/hDavwGpme8g3j0y9EdLw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12418 uniprotkb:P12236 intact:EBI-6147319|uniprotkb:A4ZY23|uniprotkb:Q8QT10|uniprotkb:Q71M35 intact:EBI-356254|ensembl:ENSP00000370808|uniprotkb:Q96C49 psi-mi:mu2_reovd(display_long)|uniprotkb:M1(gene name)|psi-mi:M1(display_short) psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10886(reovd)|taxid:10886("Reovirus type 3 (strain Dearing)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154493|imex:IM-17331-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012494(Reovirus minor core protein, Mu-2)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0044163"(host cytoskeleton) ensembl:ENSG00000169100(gene)|ensembl:ENST00000381401(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|refseq:NP_001627.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:R+r+C2QfYpM4TAOjfsS8UPyKKEk10886 rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606 intact-crc:A6A22E8305BB9F62|rigid:Q9MJXs/hDavwGpme8g3j0y9EdLw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12418 uniprotkb:Q71U36 intact:EBI-6147319|uniprotkb:A4ZY23|uniprotkb:Q8QT10|uniprotkb:Q71M35 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:mu2_reovd(display_long)|uniprotkb:M1(gene name)|psi-mi:M1(display_short) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10886(reovd)|taxid:10886("Reovirus type 3 (strain Dearing)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154493|imex:IM-17331-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012494(Reovirus minor core protein, Mu-2)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0044163"(host cytoskeleton) refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:R+r+C2QfYpM4TAOjfsS8UPyKKEk10886 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 intact-crc:A6A22E8305BB9F62|rigid:Q9MJXs/hDavwGpme8g3j0y9EdLw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01220 uniprotkb:Q02539 intact:EBI-3863691|uniprotkb:Q76ZM6 intact:EBI-932603|uniprotkb:Q3MJ34|ensembl:ENSP00000244573 psi-mi:a52_vaccw(display_long)|uniprotkb:A52R(orf name)|uniprotkb:VACWR178(locus name) psi-mi:h11_human(display_long)|uniprotkb:H1-1(gene name)|psi-mi:H1-1(display_short)|uniprotkb:H1F1(gene name synonym)|uniprotkb:HIST1H1A(gene name synonym)|uniprotkb:Histone H1a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154526|imex:IM-17331-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_233060.1|rcsb pdb:2VVW|rcsb pdb:2VVX|interpro:IPR043018|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR022819 refseq:NP_005316.1|ensembl:ENSG00000124610(gene)|ensembl:ENST00000244573(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q02539|reactome:R-HSA-140342|reactome:R-HSA-2559584 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:Wy3tYwHv75Pk7y+w77dP1XyO9bw10254 rogid:4u8P8jFM3onWx43+SxL320urjhk9606 intact-crc:FB3DC1611F30B7B6|rigid:yfaMIreaXOL57V1lNj+fwA2+ATE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01220 uniprotkb:Q5VTE0 intact:EBI-3863691|uniprotkb:Q76ZM6 intact:EBI-877809 psi-mi:a52_vaccw(display_long)|uniprotkb:A52R(orf name)|uniprotkb:VACWR178(locus name) psi-mi:ef1a3_human(display_long)|uniprotkb:EEF1A1P5(gene name)|psi-mi:EEF1A1P5(display_short)|uniprotkb:Eukaryotic elongation factor 1 A-like 3(gene name synonym)|uniprotkb:EEF1AL3(gene name synonym)|uniprotkb:Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154526|imex:IM-17331-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_233060.1|rcsb pdb:2VVW|rcsb pdb:2VVX|interpro:IPR043018|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR022819 go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR031157|reactome:R-HSA-156842|interpro:IPR027417 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:Wy3tYwHv75Pk7y+w77dP1XyO9bw10254 rogid:3t6tj3i+3CKTC1NsrHyBkeoRK789606 intact-crc:FB3DC1611F30B7B6|rigid:yfaMIreaXOL57V1lNj+fwA2+ATE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01220 uniprotkb:P07437 intact:EBI-3863691|uniprotkb:Q76ZM6 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:a52_vaccw(display_long)|uniprotkb:A52R(orf name)|uniprotkb:VACWR178(locus name) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154526|imex:IM-17331-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_233060.1|rcsb pdb:2VVW|rcsb pdb:2VVX|interpro:IPR043018|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR022819 refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:Wy3tYwHv75Pk7y+w77dP1XyO9bw10254 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:FB3DC1611F30B7B6|rigid:yfaMIreaXOL57V1lNj+fwA2+ATE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01220 uniprotkb:P13637 intact:EBI-3863691|uniprotkb:Q76ZM6 intact:EBI-948169|uniprotkb:Q16732|uniprotkb:Q16735|uniprotkb:Q969K5|ensembl:ENSP00000498113|uniprotkb:B7Z2T0|uniprotkb:B7Z401|uniprotkb:F5H6J6 psi-mi:a52_vaccw(display_long)|uniprotkb:A52R(orf name)|uniprotkb:VACWR178(locus name) psi-mi:at1a3_human(display_long)|uniprotkb:Sodium pump subunit alpha-3(gene name synonym)|uniprotkb:"Na(+)/K(+) ATPase alpha(III) subunit"(gene name synonym)|uniprotkb:ATP1A3(gene name)|psi-mi:ATP1A3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154526|imex:IM-17331-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_233060.1|rcsb pdb:2VVW|rcsb pdb:2VVX|interpro:IPR043018|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR022819 refseq:NP_689509.1|ensembl:ENSG00000105409(gene)|ensembl:ENST00000648268(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030424"(axon)|go:"GO:0031090"(organelle membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060075"(regulation of resting membrane potential)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0098984"(neuron to neuron synapse)|go:"GO:0099520"(ion antiporter activity involved in regulation of presynaptic membrane potential)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1903416"(response to glycoside)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P13637|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|refseq:NP_001243142.1|refseq:NP_001243143.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:Wy3tYwHv75Pk7y+w77dP1XyO9bw10254 rogid:iDlxP7yaZPX85GQKmHOe0KvnS2w9606 intact-crc:FB3DC1611F30B7B6|rigid:yfaMIreaXOL57V1lNj+fwA2+ATE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01220 uniprotkb:P42336 intact:EBI-3863691|uniprotkb:Q76ZM6 intact:EBI-2116585|uniprotkb:Q14CW1|uniprotkb:Q99762|ensembl:ENSP00000263967 psi-mi:a52_vaccw(display_long)|uniprotkb:A52R(orf name)|uniprotkb:VACWR178(locus name) psi-mi:pk3ca_human(display_long)|uniprotkb:Phosphoinositide-3-kinase catalytic alpha polypeptide(gene name synonym)|uniprotkb:Serine/threonine protein kinase PIK3CA(gene name synonym)|uniprotkb:PIK3CA(gene name)|psi-mi:PIK3CA(display_short)|uniprotkb:Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha(gene name synonym)|uniprotkb:Phosphoinositide 3-kinase alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154526|imex:IM-17331-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_233060.1|rcsb pdb:2VVW|rcsb pdb:2VVX|interpro:IPR043018|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR022819 refseq:XP_011511196.1|refseq:XP_006713721.1|refseq:NP_006209.2|dip:DIP-42728N|ensembl:ENSG00000121879(gene)|ensembl:ENST00000263967(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001944"(vasculature development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0005944"(phosphatidylinositol 3-kinase complex, class IB)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006909"(phagocytosis)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030168"(platelet activation)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035004"(phosphatidylinositol 3-kinase activity)|go:"GO:0035005"(1-phosphatidylinositol-4-phosphate 3-kinase activity)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0038028"(insulin receptor signaling pathway via phosphatidylinositol 3-kinase)|go:"GO:0038084"(vascular endothelial growth factor signaling pathway)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0043276"(anoikis)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044029"(hypomethylation of CpG island)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046934"(phosphatidylinositol-4,5-bisphosphate 3-kinase activity)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110053"(regulation of actin filament organization)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR000341(Phosphoinositide 3-kinase, ras-binding)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR003113(Phosphatidylinositol 3-kinase, p85-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR029071|interpro:IPR035892|interpro:IPR036940|interpro:IPR037704|interpro:IPR042236|mint:P42336|rcsb pdb:2ENQ|rcsb pdb:2RD0|rcsb pdb:3HHM|rcsb pdb:3HIZ|rcsb pdb:3ZIM|rcsb pdb:4JPS|rcsb pdb:4L1B|rcsb pdb:4L23|rcsb pdb:4L2Y|rcsb pdb:4OVU|rcsb pdb:4OVV|rcsb pdb:4TUU|rcsb pdb:4TV3|rcsb pdb:4WAF|rcsb pdb:4YKN|rcsb pdb:4ZOP|rcsb pdb:5DXT|rcsb pdb:5FI4|rcsb pdb:5ITD|rcsb pdb:5SW8|rcsb pdb:5SWG|rcsb pdb:5SWO|rcsb pdb:5SWP|rcsb pdb:5SWR|rcsb pdb:5SWT|rcsb pdb:5SX8|rcsb pdb:5SX9|rcsb pdb:5SXA|rcsb pdb:5SXB|rcsb pdb:5SXC|rcsb pdb:5SXD|rcsb pdb:5SXE|rcsb pdb:5SXF|rcsb pdb:5SXI|rcsb pdb:5SXJ|rcsb pdb:5SXK|rcsb pdb:5UBR|rcsb pdb:5UK8|rcsb pdb:5UKJ|rcsb pdb:5UL1|rcsb pdb:5XGH|rcsb pdb:5XGI|rcsb pdb:5XGJ|rcsb pdb:6GVF|rcsb pdb:6GVG|rcsb pdb:6GVH|rcsb pdb:6GVI|rcsb pdb:6NCT|rcsb pdb:6OAC|rcsb pdb:6PYS|rcsb pdb:6VO7|rcsb pdb:7JIU|rcsb pdb:7K6M|rcsb pdb:7K6N|rcsb pdb:7K6O|rcsb pdb:7K71|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1236382|reactome:R-HSA-1250342|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-180292|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-1963642|reactome:R-HSA-198203|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654689|reactome:R-HSA-5654695|reactome:R-HSA-5654710|reactome:R-HSA-5654720|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-9009391|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9027276|reactome:R-HSA-9028335|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9603381|reactome:R-HSA-9607240|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|rcsb pdb:5DXH|reactome:R-HSA-9703465|reactome:R-HSA-9703648 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:Wy3tYwHv75Pk7y+w77dP1XyO9bw10254 rogid:YIZWt9VfCmyBCWYkqAEaMAEsl3w9606 intact-crc:FB3DC1611F30B7B6|rigid:yfaMIreaXOL57V1lNj+fwA2+ATE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01220 uniprotkb:P12236 intact:EBI-3863691|uniprotkb:Q76ZM6 intact:EBI-356254|ensembl:ENSP00000370808|uniprotkb:Q96C49 psi-mi:a52_vaccw(display_long)|uniprotkb:A52R(orf name)|uniprotkb:VACWR178(locus name) psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154526|imex:IM-17331-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_233060.1|rcsb pdb:2VVW|rcsb pdb:2VVX|interpro:IPR043018|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR022819 ensembl:ENSG00000169100(gene)|ensembl:ENST00000381401(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|refseq:NP_001627.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:Wy3tYwHv75Pk7y+w77dP1XyO9bw10254 rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606 intact-crc:FB3DC1611F30B7B6|rigid:yfaMIreaXOL57V1lNj+fwA2+ATE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01220 uniprotkb:O00459 intact:EBI-3863691|uniprotkb:Q76ZM6 intact:EBI-346930|uniprotkb:Q5EAT5|uniprotkb:Q9UPH9|intact:EBI-28974273|ensembl:ENSP00000222254 psi-mi:a52_vaccw(display_long)|uniprotkb:A52R(orf name)|uniprotkb:VACWR178(locus name) psi-mi:p85b_human(display_long)|uniprotkb:PIK3R2(gene name)|psi-mi:PIK3R2(display_short)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154526|imex:IM-17331-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_233060.1|rcsb pdb:2VVW|rcsb pdb:2VVX|interpro:IPR043018|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR022819 ensembl:ENSP00000222254|refseq:NP_005018.1|dip:DIP-31811N|ensembl:ENSG00000105647(gene)|ensembl:ENST00000222254(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|rcsb pdb:6OX7|rcsb pdb:6U28|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-186763|reactome:R-HSA-198203|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|mint:O00459|rcsb pdb:2KT1|rcsb pdb:2XS6|rcsb pdb:3MTT|rcsb pdb:3O5Z|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-210993|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9013409 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:Wy3tYwHv75Pk7y+w77dP1XyO9bw10254 rogid:Ij0WS0eKPwShgFWQc7OEss7AcAU9606 intact-crc:FB3DC1611F30B7B6|rigid:yfaMIreaXOL57V1lNj+fwA2+ATE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01220 uniprotkb:P05141 intact:EBI-3863691|uniprotkb:Q76ZM6 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:a52_vaccw(display_long)|uniprotkb:A52R(orf name)|uniprotkb:VACWR178(locus name) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154526|imex:IM-17331-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_233060.1|rcsb pdb:2VVW|rcsb pdb:2VVX|interpro:IPR043018|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR022819 refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:Wy3tYwHv75Pk7y+w77dP1XyO9bw10254 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:FB3DC1611F30B7B6|rigid:yfaMIreaXOL57V1lNj+fwA2+ATE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01220 uniprotkb:P42338 intact:EBI-3863691|uniprotkb:Q76ZM6 intact:EBI-2609540|uniprotkb:D3DNF0|uniprotkb:Q24JU2|ensembl:ENSP00000289153|ensembl:ENSP00000418143|ensembl:ENSP00000501150 psi-mi:a52_vaccw(display_long)|uniprotkb:A52R(orf name)|uniprotkb:VACWR178(locus name) psi-mi:pk3cb_human(display_long)|uniprotkb:PIK3CB(gene name)|psi-mi:PIK3CB(display_short)|uniprotkb:PIK3C1(gene name synonym)|uniprotkb:Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154526|imex:IM-17331-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_233060.1|rcsb pdb:2VVW|rcsb pdb:2VVX|interpro:IPR043018|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR022819 refseq:NP_006210.1|refseq:XP_011511197.1|refseq:XP_005247587.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0030168"(platelet activation)|go:"GO:0030496"(midbody)|go:"GO:0033031"(positive regulation of neutrophil apoptotic process)|go:"GO:0035004"(phosphatidylinositol 3-kinase activity)|go:"GO:0035005"(1-phosphatidylinositol-4-phosphate 3-kinase activity)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046934"(phosphatidylinositol-4,5-bisphosphate 3-kinase activity)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0070527"(platelet aggregation)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR000341(Phosphoinositide 3-kinase, ras-binding)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR003113(Phosphatidylinositol 3-kinase, p85-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR029071|interpro:IPR035892|interpro:IPR036940|interpro:IPR037702|interpro:IPR042236|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1660499|reactome:R-HSA-186763|reactome:R-HSA-198203|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8853659|reactome:R-HSA-9027276|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9673767|reactome:R-HSA-9673770|ensembl:ENSG00000051382(gene)|ensembl:ENST00000289153(transcript)|ensembl:ENST00000477593(transcript)|ensembl:ENST00000674063(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001952"(regulation of cell-matrix adhesion)|go:"GO:0002931"(response to ischemia)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_006713722.1|refseq:XP_016862108.1|dip:DIP-44775N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:Wy3tYwHv75Pk7y+w77dP1XyO9bw10254 rogid:Nga6TlSCXWs2NVRR5XfxvnLfWUk9606 intact-crc:FB3DC1611F30B7B6|rigid:yfaMIreaXOL57V1lNj+fwA2+ATE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01220 uniprotkb:P27986 intact:EBI-3863691|uniprotkb:Q76ZM6 intact:EBI-79464|intact:EBI-28974553|ensembl:ENSP00000428056|ensembl:ENSP00000429277|uniprotkb:Q15747|uniprotkb:Q4VBZ7|uniprotkb:Q53EM6|uniprotkb:Q8IXA2|uniprotkb:Q8N1C5|uniprotkb:D3DWA0|uniprotkb:B3KT19|uniprotkb:E7EX19 psi-mi:a52_vaccw(display_long)|uniprotkb:A52R(orf name)|uniprotkb:VACWR178(locus name) psi-mi:p85a_human(display_long)|uniprotkb:PIK3R1(gene name)|psi-mi:PIK3R1(display_short)|uniprotkb:GRB1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154526|imex:IM-17331-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_233060.1|rcsb pdb:2VVW|rcsb pdb:2VVX|interpro:IPR043018|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR022819 refseq:NP_001229395.1|refseq:NP_852556.2|refseq:NP_852664.1|refseq:NP_852665.1|ensembl:ENSG00000145675(gene)|ensembl:ENST00000521381(transcript)|ensembl:ENST00000521657(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|ensembl:ENST00000320694|ensembl:ENSP00000323512|ensembl:ENST00000336483|ensembl:ENSP00000338554|ensembl:ENSP00000428056|ensembl:ENSP00000429277|ensembl:ENST00000523872|ensembl:ENSP00000430098|rcsb pdb:5SXA|rcsb pdb:5SXB|rcsb pdb:5SXC|rcsb pdb:5SXD|rcsb pdb:5SXE|rcsb pdb:5SXF|rcsb pdb:5SXI|rcsb pdb:5SXJ|rcsb pdb:5SXK|rcsb pdb:5UBT|rcsb pdb:5UK8|rcsb pdb:5UKJ|rcsb pdb:5SX9|rcsb pdb:5UL1|rcsb pdb:5VLR|rcsb pdb:5XGH|rcsb pdb:5XGI|rcsb pdb:5XGJ|rcsb pdb:6NCT|rcsb pdb:6PYR|rcsb pdb:6PYU|reactome:R-HSA-1660499|rcsb pdb:7CIO|rcsb pdb:7LM2|reactome:R-HSA-180292|reactome:R-HSA-109704|reactome:R-HSA-1839117|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1236382|reactome:R-HSA-186763|reactome:R-HSA-1963642|reactome:R-HSA-1250342|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-198203|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-1433557|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-430116|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654689|reactome:R-HSA-5654695|reactome:R-HSA-5654710|reactome:R-HSA-5654720|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9603381|reactome:R-HSA-9607240|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-983695|reactome:R-HSA-5655253|reactome:R-HSA-5655302|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-6811558|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-5655291|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9027276|reactome:R-HSA-9028335|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0043559"(insulin binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1990578"(perinuclear endoplasmic reticulum membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035591|interpro:IPR036028|interpro:IPR036860|interpro:IPR044124|mint:P27986|rcsb pdb:1A0N|rcsb pdb:1AZG|rcsb pdb:1H9O|rcsb pdb:1PBW|rcsb pdb:1PHT|rcsb pdb:1PIC|rcsb pdb:1PKS|rcsb pdb:1PKT|rcsb pdb:2IUG|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|rcsb pdb:2IUH|rcsb pdb:2IUI|rcsb pdb:2RD0|rcsb pdb:3HHM|rcsb pdb:3HIZ|rcsb pdb:3I5R|rcsb pdb:3I5S|rcsb pdb:4A55|rcsb pdb:4JPS|rcsb pdb:4L1B|rcsb pdb:4L23|rcsb pdb:4L2Y|rcsb pdb:4OVU|rcsb pdb:4OVV|rcsb pdb:4WAF|rcsb pdb:4YKN|rcsb pdb:4ZOP|rcsb pdb:5AUL|rcsb pdb:5FI4|rcsb pdb:5GJI|rcsb pdb:5ITD|rcsb pdb:5M6U|rcsb pdb:5SW8|rcsb pdb:5SWG|rcsb pdb:5SWO|rcsb pdb:2V1Y|rcsb pdb:5SWP|rcsb pdb:5SWR|rcsb pdb:5SWT|rcsb pdb:5SX8|refseq:XP_016865074.1|refseq:XP_005248599.1|dip:DIP-119N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:Wy3tYwHv75Pk7y+w77dP1XyO9bw10254 rogid:pANLtVCSWVr64OXaS6bCjGBwfig9606 intact-crc:FB3DC1611F30B7B6|rigid:yfaMIreaXOL57V1lNj+fwA2+ATE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01220 uniprotkb:Q00325 intact:EBI-3863691|uniprotkb:Q76ZM6 intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34 psi-mi:a52_vaccw(display_long)|uniprotkb:A52R(orf name)|uniprotkb:VACWR178(locus name) psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154526|imex:IM-17331-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_233060.1|rcsb pdb:2VVW|rcsb pdb:2VVX|interpro:IPR043018|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR022819 ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325 - - crc64:78714C85931B22D5 figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:Wy3tYwHv75Pk7y+w77dP1XyO9bw10254 rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606 intact-crc:FB3DC1611F30B7B6|rigid:yfaMIreaXOL57V1lNj+fwA2+ATE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01220 uniprotkb:Q92569 intact:EBI-3863691|uniprotkb:Q76ZM6 intact:EBI-79893|intact:EBI-28975437|ensembl:ENSP00000262741|ensembl:ENSP00000361075|ensembl:ENSP00000412546|uniprotkb:O60482|uniprotkb:Q5T4P2|uniprotkb:B2R9C1|uniprotkb:Q5T4P1|uniprotkb:D3DQ12 psi-mi:a52_vaccw(display_long)|uniprotkb:A52R(orf name)|uniprotkb:VACWR178(locus name) psi-mi:p55g_human(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma(gene name synonym)|uniprotkb:PIK3R3(gene name)|psi-mi:PIK3R3(display_short)|uniprotkb:p55PIK(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154526|imex:IM-17331-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_233060.1|rcsb pdb:2VVW|rcsb pdb:2VVX|interpro:IPR043018|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR022819 reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9670439|ensembl:ENSG00000117461(gene)|ensembl:ENST00000262741(transcript)|ensembl:ENST00000372006(transcript)|ensembl:ENST00000420542(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|interpro:IPR000980(SH2 motif)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR036860|mint:Q92569|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-2219530|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-512988|reactome:R-HSA-6811558|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|reactome:R-HSA-8853659|reactome:R-HSA-9009391|refseq:NP_001107644.1|refseq:NP_003620.3|ensembl:ENSP00000262741|ensembl:ENSP00000361075|ensembl:ENSP00000412546|ensembl:ENST00000423209|ensembl:ENSP00000391431|dip:DIP-30925N|refseq:NP_001290358.1|refseq:XP_016858103.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:Wy3tYwHv75Pk7y+w77dP1XyO9bw10254 rogid:oIVTuGRhg/Kn3h+Br1EfiAtiAQQ9606 intact-crc:FB3DC1611F30B7B6|rigid:yfaMIreaXOL57V1lNj+fwA2+ATE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01220 uniprotkb:P05023 intact:EBI-3863691|uniprotkb:Q76ZM6 intact:EBI-358778|uniprotkb:Q16689|uniprotkb:Q6LDM4|uniprotkb:Q9UJ20|uniprotkb:Q9UJ21|uniprotkb:B2RBR6|uniprotkb:Q9UCN1|ensembl:ENSP00000295598|uniprotkb:B7Z3U6|uniprotkb:B7Z2T5|uniprotkb:F5H3A1|intact:EBI-10963133 psi-mi:a52_vaccw(display_long)|uniprotkb:A52R(orf name)|uniprotkb:VACWR178(locus name) psi-mi:at1a1_human(display_long)|uniprotkb:ATP1A1(gene name)|psi-mi:ATP1A1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154526|imex:IM-17331-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_233060.1|rcsb pdb:2VVW|rcsb pdb:2VVX|interpro:IPR043018|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR022819 refseq:NP_000692.2|refseq:NP_001153705.1|refseq:NP_001153706.1|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|ensembl:ENSG00000163399(gene)|ensembl:ENST00000295598(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903416"(response to glycoside)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P05023|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|refseq:XP_016856849.1|refseq:XP_016856850.1|dip:DIP-38196N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:Wy3tYwHv75Pk7y+w77dP1XyO9bw10254 rogid:uZf9iX38kcZh0Q+apz8uB17EtJw9606 intact-crc:FB3DC1611F30B7B6|rigid:yfaMIreaXOL57V1lNj+fwA2+ATE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01220 uniprotkb:Q71U36 intact:EBI-3863691|uniprotkb:Q76ZM6 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:a52_vaccw(display_long)|uniprotkb:A52R(orf name)|uniprotkb:VACWR178(locus name) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154526|imex:IM-17331-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_233060.1|rcsb pdb:2VVW|rcsb pdb:2VVX|interpro:IPR043018|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR022819 refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:Wy3tYwHv75Pk7y+w77dP1XyO9bw10254 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 intact-crc:FB3DC1611F30B7B6|rigid:yfaMIreaXOL57V1lNj+fwA2+ATE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01220 uniprotkb:Q05639 intact:EBI-3863691|uniprotkb:Q76ZM6 intact:EBI-354943|ensembl:ENSP00000217182|uniprotkb:P54266|uniprotkb:Q0VGC7|uniprotkb:B5BUF3|uniprotkb:E1P5J1 psi-mi:a52_vaccw(display_long)|uniprotkb:A52R(orf name)|uniprotkb:VACWR178(locus name) psi-mi:ef1a2_human(display_long)|uniprotkb:EEF1A2(gene name)|psi-mi:EEF1A2(display_short)|uniprotkb:EEF1AL(gene name synonym)|uniprotkb:STN(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-2(gene name synonym)|uniprotkb:Statin-S1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154526|imex:IM-17331-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_233060.1|rcsb pdb:2VVW|rcsb pdb:2VVX|interpro:IPR043018|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR022819 ensembl:ENSG00000101210(gene)|ensembl:ENST00000217182(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0090218"(positive regulation of lipid kinase activity)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:Q05639|rcsb pdb:3C5J|reactome:R-HSA-156842|refseq:NP_001949.1|dip:DIP-40060N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:Wy3tYwHv75Pk7y+w77dP1XyO9bw10254 rogid:vFXfcSRokxKo5RW0tRE1qEK0NKw9606 intact-crc:FB3DC1611F30B7B6|rigid:yfaMIreaXOL57V1lNj+fwA2+ATE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01220 uniprotkb:P22492 intact:EBI-3863691|uniprotkb:Q76ZM6 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 psi-mi:a52_vaccw(display_long)|uniprotkb:A52R(orf name)|uniprotkb:VACWR178(locus name) psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154526|imex:IM-17331-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_233060.1|rcsb pdb:2VVW|rcsb pdb:2VVX|interpro:IPR043018|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR022819 refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:Wy3tYwHv75Pk7y+w77dP1XyO9bw10254 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 intact-crc:FB3DC1611F30B7B6|rigid:yfaMIreaXOL57V1lNj+fwA2+ATE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01220 uniprotkb:P12235 intact:EBI-3863691|uniprotkb:Q76ZM6 intact:EBI-359074|uniprotkb:D3DP59|ensembl:ENSP00000281456 psi-mi:a52_vaccw(display_long)|uniprotkb:A52R(orf name)|uniprotkb:VACWR178(locus name) psi-mi:adt1_human(display_long)|uniprotkb:SLC25A4(gene name)|psi-mi:SLC25A4(display_short)|uniprotkb:ANT1(gene name synonym)|uniprotkb:Adenine nucleotide translocator 1(gene name synonym)|uniprotkb:ADP,ATP carrier protein 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 4(gene name synonym)|uniprotkb:ADP,ATP carrier protein, heart/skeletal muscle isoform T1(gene name synonym)|uniprotkb:AAC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154526|imex:IM-17331-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_233060.1|rcsb pdb:2VVW|rcsb pdb:2VVX|interpro:IPR043018|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR022819 refseq:NP_001142.2|ensembl:ENST00000281456(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0015866"(ADP transport)|ensembl:ENSG00000151729(gene)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12235|reactome:R-HSA-1268020|reactome:R-HSA-180897|reactome:R-HSA-83936|dip:DIP-33116N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:Wy3tYwHv75Pk7y+w77dP1XyO9bw10254 rogid:vs4XIUUUypcIHR9Lz4j1buDAnjM9606 intact-crc:FB3DC1611F30B7B6|rigid:yfaMIreaXOL57V1lNj+fwA2+ATE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01220 uniprotkb:P68104 intact:EBI-3863691|uniprotkb:Q76ZM6 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:a52_vaccw(display_long)|uniprotkb:A52R(orf name)|uniprotkb:VACWR178(locus name) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154526|imex:IM-17331-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_233060.1|rcsb pdb:2VVW|rcsb pdb:2VVX|interpro:IPR043018|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR022819 refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:Wy3tYwHv75Pk7y+w77dP1XyO9bw10254 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 intact-crc:FB3DC1611F30B7B6|rigid:yfaMIreaXOL57V1lNj+fwA2+ATE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01220 uniprotkb:Q9BQE3 intact:EBI-3863691|uniprotkb:Q76ZM6 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:a52_vaccw(display_long)|uniprotkb:A52R(orf name)|uniprotkb:VACWR178(locus name) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154526|imex:IM-17331-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_233060.1|rcsb pdb:2VVW|rcsb pdb:2VVX|interpro:IPR043018|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR022819 reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:Wy3tYwHv75Pk7y+w77dP1XyO9bw10254 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:FB3DC1611F30B7B6|rigid:yfaMIreaXOL57V1lNj+fwA2+ATE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P12235 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-359074|uniprotkb:D3DP59|ensembl:ENSP00000281456 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:adt1_human(display_long)|uniprotkb:SLC25A4(gene name)|psi-mi:SLC25A4(display_short)|uniprotkb:ANT1(gene name synonym)|uniprotkb:Adenine nucleotide translocator 1(gene name synonym)|uniprotkb:ADP,ATP carrier protein 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 4(gene name synonym)|uniprotkb:ADP,ATP carrier protein, heart/skeletal muscle isoform T1(gene name synonym)|uniprotkb:AAC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001142.2|ensembl:ENST00000281456(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0015866"(ADP transport)|ensembl:ENSG00000151729(gene)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12235|reactome:R-HSA-1268020|reactome:R-HSA-180897|reactome:R-HSA-83936|dip:DIP-33116N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:vs4XIUUUypcIHR9Lz4j1buDAnjM9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q9Y3I0 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-2107208|uniprotkb:Q6IAI0|uniprotkb:Q9BWL4|uniprotkb:Q9NTH1|uniprotkb:Q9P037|uniprotkb:Q9P0J3|uniprotkb:B2R6A8|intact:EBI-4399544|ensembl:ENSP00000216038 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rtcb_human(display_long)|uniprotkb:3'-phosphate/5'-hydroxy nucleic acid ligase(gene name synonym)|uniprotkb:C22orf28(gene name synonym)|uniprotkb:HSPC117(orf name)|uniprotkb:RTCB(gene name)|psi-mi:RTCB(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_055121.1|dip:DIP-46750N|ensembl:ENSG00000100220(gene)|ensembl:ENST00000216038(transcript)|go:"GO:0000971"(tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate)|go:"GO:0003723"(RNA binding)|go:"GO:0003972"("RNA ligase (ATP) activity")|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0017166"(vinculin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0072669"(tRNA-splicing ligase complex)|interpro:IPR001233(Protein of unknown function UPF0027)|interpro:IPR027513|interpro:IPR036025|mint:Q9Y3I0|reactome:R-HSA-6784531 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:URuCEq/DIn6DgR3jOb5fwnpDVXE9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q71U36 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q5VTE0 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-877809 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ef1a3_human(display_long)|uniprotkb:EEF1A1P5(gene name)|psi-mi:EEF1A1P5(display_short)|uniprotkb:Eukaryotic elongation factor 1 A-like 3(gene name synonym)|uniprotkb:EEF1AL3(gene name synonym)|uniprotkb:Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR031157|reactome:R-HSA-156842|interpro:IPR027417 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:3t6tj3i+3CKTC1NsrHyBkeoRK789606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q7L2E3 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1211456|uniprotkb:O94965|uniprotkb:Q7Z753|uniprotkb:Q96CH4|uniprotkb:Q9NUQ0|uniprotkb:A8K5F1|ensembl:ENSP00000392601|ensembl:ENSP00000405620|intact:EBI-21350949 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:dhx30_human(display_long)|uniprotkb:DHX30(gene name)|psi-mi:DHX30(display_short)|uniprotkb:KIAA0890(gene name synonym)|uniprotkb:DDX30(gene name synonym)|uniprotkb:DEAH box protein 30(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_055781.2|refseq:NP_619520.1|refseq:XP_011531796.1|refseq:XP_011531797.1|refseq:XP_016861406.1|ensembl:ENSG00000132153(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007417"(central nervous system development)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902775"(mitochondrial large ribosomal subunit assembly)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|mint:Q7L2E3|rcsb pdb:2DB2|ensembl:ENST00000445061(transcript)|ensembl:ENST00000446256(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:tb4GzZKLycraXS0NlVqj8reV3IQ9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P68371 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q9HCE1 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028|ensembl:ENSP00000358659|ensembl:ENSP00000399797 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|refseq:NP_001308253.1|ensembl:ENSG00000155363(gene)|ensembl:ENST00000357443(transcript)|ensembl:ENST00000369645(transcript)|ensembl:ENST00000413052(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043186"(P granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041679|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-8936459|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q08380 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-354956|ensembl:ENSP00000262776|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000108679(gene)|ensembl:ENST00000262776(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017448(Speract/scavenger receptor related)|go:"GO:0007155"(cell adhesion)|interpro:IPR036772|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|refseq:NP_005558.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q14103 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-299674|ensembl:ENSP00000313199|uniprotkb:P07029|uniprotkb:Q01858|uniprotkb:Q14100|uniprotkb:Q14101|uniprotkb:Q14102|uniprotkb:Q4W5A1|uniprotkb:A8K9J2|uniprotkb:Q9UCE8|uniprotkb:Q9UCE9 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpd_human(display_long)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000138668(gene)|ensembl:ENST00000313899(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021549"(cerebellum development)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:1901355"(response to rapamycin)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904383"(response to sodium phosphate)|go:"GO:1904586"(cellular response to putrescine)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990828"(hepatocyte dedifferentiation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR035979|mint:Q14103|rcsb pdb:1HD0|rcsb pdb:1HD1|rcsb pdb:1IQT|rcsb pdb:1WTB|rcsb pdb:1X0F|rcsb pdb:2Z5N|rcsb pdb:5IM0|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|reactome:R-HSA-450408|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:NP_001003810.1|refseq:NP_002129.2|refseq:NP_112737.1|refseq:NP_112738.1|dip:DIP-31163N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:LrC0nOpN6jGn3WELs5NEOccNPnw9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q00839 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-351126|uniprotkb:O75507|uniprotkb:Q8N174|uniprotkb:Q96HY9|uniprotkb:Q9BQ09|ensembl:ENSP00000491215 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpu_human(display_long)|uniprotkb:HNRNPU(gene name)|psi-mi:HNRNPU(display_short)|uniprotkb:SAFA(gene name synonym)|uniprotkb:U21.1(gene name synonym)|uniprotkb:HNRPU(gene name synonym)|uniprotkb:p120(gene name synonym)|uniprotkb:pp120(gene name synonym)|uniprotkb:C1orf199(gene name synonym)|uniprotkb:GRIP120(gene name synonym)|uniprotkb:Nuclear p120 ribonucleoprotein(gene name synonym)|uniprotkb:Scaffold-attachment factor A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_004492.2|refseq:NP_114032.2|ensembl:ENSG00000153187(gene)|ensembl:ENST00000640218(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:1990498"(mitotic spindle microtubule)|go:"GO:0098577"(inactive sex chromosome)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR026745|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q00839|rcsb pdb:1ZRJ|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990280"(RNA localization to chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006396"(RNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008143"("poly(A) binding")|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0017130"("poly(C) RNA binding")|go:"GO:0030496"(midbody)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|refseq:XP_016856604.1|refseq:XP_016856605.1|refseq:XP_016856606.1|dip:DIP-684N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:n73PY0Vis+D5Iq0q77h5Ck2V4789606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P15880 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-443446|ensembl:ENSP00000341885|uniprotkb:Q3MIB1|uniprotkb:B2R5G0|uniprotkb:D3DU82 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs2_human(display_long)|uniprotkb:RPS2(gene name)|psi-mi:RPS2(display_short)|uniprotkb:RPS4(gene name synonym)|uniprotkb:40S ribosomal protein S4(gene name synonym)|uniprotkb:Protein LLRep3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|rcsb pdb:6OLG|rcsb pdb:6OLI|interpro:IPR018192|rcsb pdb:6OLZ|interpro:IPR020568|mint:P15880|rcsb pdb:4UG0|rcsb pdb:6OM0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6EK0|rcsb pdb:6G18|rcsb pdb:6XA1|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6G5H|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7JQB|rcsb pdb:7JQC|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-3214858|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8876725|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:7A09|ensembl:ENSG00000140988(gene)|ensembl:ENST00000343262(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045296"(cadherin binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR005711(Ribosomal protein S5, eukaryotic/archaeal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|refseq:NP_002943.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:JUr2Y3cGk00S8KaTVPymshfaHhc9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q86YZ3 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1047017|uniprotkb:Q5U1F4|ensembl:ENSP00000357791|uniprotkb:Q5DT20 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:horn_human(display_long)|uniprotkb:HRNR(gene name)|psi-mi:HRNR(display_short)|uniprotkb:S100A18(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001009931.1|ensembl:ENSG00000197915(gene)|ensembl:ENST00000368801(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031424"(keratinization)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036457"(keratohyalin granule)|go:"GO:0043163"(cell envelope organization)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR033201|interpro:IPR034325|mint:Q86YZ3|reactome:R-HSA-6798695|ensembl:ENSP00000357791 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:j5ATFM7OQGbf5j+CZpJ3bJoadnc9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P68104 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P12036 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-2880271|uniprotkb:Q9UQ14|uniprotkb:Q9UJS7|uniprotkb:Q96HF8|uniprotkb:B4DYY4|ensembl:ENSP00000311997 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:nfh_human(display_long)|uniprotkb:NEFH(gene name)|psi-mi:NEFH(display_short)|uniprotkb:KIAA0845(gene name synonym)|uniprotkb:NFH(gene name synonym)|uniprotkb:200 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament triplet H protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_066554.2|ensembl:ENSG00000100285(gene)|ensembl:ENST00000310624(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005883"(neurofilament)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0061564"(axon development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR010790(Protein of unknown function DUF1388)|interpro:IPR018039|interpro:IPR033183|interpro:IPR039008|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:TXMrn6SWBHIYQY1loZfVvMo9PtU9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q9Y6M1 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1024419|intact:EBI-1059063|intact:EBI-1237206|uniprotkb:A0A4Z0|uniprotkb:B3FTN2|uniprotkb:B3FTN3|uniprotkb:B3FTN4|ensembl:ENSP00000371634 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:if2b2_human(display_long)|uniprotkb:IGF-II mRNA-binding protein 2(gene name synonym)|uniprotkb:Hepatocellular carcinoma autoantigen p62(gene name synonym)|uniprotkb:VICKZ family member 2(gene name synonym)|uniprotkb:IGF2BP2(gene name)|psi-mi:IGF2BP2(display_short)|uniprotkb:IMP2(gene name synonym)|uniprotkb:VICKZ2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001278801.1|refseq:NP_001278802.1|refseq:NP_001278803.1|refseq:NP_001278804.1|refseq:NP_001007226.1|refseq:NP_006539.3|ensembl:ENSG00000073792(gene)|ensembl:ENST00000382199(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR028743|interpro:IPR034843|interpro:IPR035979|interpro:IPR036612|mint:Q9Y6M1|rcsb pdb:2CQH|rcsb pdb:6ROL|reactome:R-HSA-428359|dip:DIP-35539N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:k45UViReMAxCv2cu7+tx+auevQc9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q86U42 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1226435|uniprotkb:O43484|uniprotkb:D3DS49|ensembl:ENSP00000216727 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pabp2_human(display_long)|uniprotkb:PABPN1(gene name)|psi-mi:PABPN1(display_short)|uniprotkb:PAB2(gene name synonym)|uniprotkb:PABP2(gene name synonym)|uniprotkb:"Poly(A)-binding protein II"(gene name synonym)|uniprotkb:Polyadenylate-binding nuclear protein 1(gene name synonym)|uniprotkb:"Nuclear poly(A)-binding protein 1"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_004634.1|dip:DIP-37968N|go:"GO:0000165"(MAPK cascade)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|ensembl:ENSG00000100836(gene)|ensembl:ENST00000216727(transcript)|go:"GO:0006936"(muscle contraction)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1904247"(positive regulation of polynucleotide adenylyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034911|interpro:IPR035979|mint:Q86U42|rcsb pdb:3B4D|rcsb pdb:3B4M|rcsb pdb:3UCG|reactome:R-HSA-168315|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0070063"(RNA polymerase binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:NxWuFTvVqshfu+ZIsZMIZEdSk2k9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:O00425 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1058566|ensembl:ENSP00000258729|uniprotkb:Q63HM0|uniprotkb:A0A4Z5|uniprotkb:Q6MZZ2|uniprotkb:Q86VB1|intact:EBI-2560196 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:if2b3_human(display_long)|uniprotkb:IGF2BP3(gene name)|psi-mi:IGF2BP3(display_short)|uniprotkb:IMP3(gene name synonym)|uniprotkb:KOC1(gene name synonym)|uniprotkb:VICKZ3(gene name synonym)|uniprotkb:IGF-II mRNA-binding protein 3(gene name synonym)|uniprotkb:KH domain-containing protein overexpressed in cancer(gene name synonym)|uniprotkb:VICKZ family member 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000136231(gene)|ensembl:ENST00000258729(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007399"(nervous system development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_006538.2|interpro:IPR004087(K Homology)|dip:DIP-44171N|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034844|interpro:IPR035979|interpro:IPR036612|mint:O00425|rcsb pdb:2E44|rcsb pdb:6FQ1|rcsb pdb:6FQR|rcsb pdb:6GQE|rcsb pdb:6GX6|reactome:R-HSA-428359 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:yGEnYHFP+P05J45ZnHUdcPXHlQA9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q13151 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-724092|ensembl:ENSP00000316042|intact:EBI-1043661|uniprotkb:Q6IB18 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:roa0_human(display_long)|uniprotkb:HNRPA0(gene name synonym)|uniprotkb:HNRNPA0(gene name)|psi-mi:HNRNPA0(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_006796.1|ensembl:ENSG00000177733(gene)|ensembl:ENST00000314940(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006954"(inflammatory response)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034801|interpro:IPR035979|mint:Q13151|reactome:R-HSA-72163|reactome:R-HSA-72203 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:buyQxR8FLxd4N6jRhwVsroeGrBw9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:O14979 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-299727|ensembl:ENSP00000295470|ensembl:ENSP00000422040|ensembl:ENSP00000483254|uniprotkb:Q6SPF2|uniprotkb:Q7KZ74|uniprotkb:Q7KZ75|uniprotkb:Q96IM0|uniprotkb:Q96S43 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrdl_human(display_long)|uniprotkb:HNRNPDL(gene name)|psi-mi:HNRNPDL(display_short)|uniprotkb:AU-rich element RNA-binding factor(gene name synonym)|uniprotkb:HNRPDL(gene name synonym)|uniprotkb:JKT41-binding protein(gene name synonym)|uniprotkb:JKTBP(gene name synonym)|uniprotkb:Protein laAUF1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000152795(gene)|ensembl:ENST00000295470(transcript)|ensembl:ENST00000502762(transcript)|ensembl:ENST00000621267(transcript)|go:"GO:0003677"(DNA binding)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034847|interpro:IPR035979|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|mint:O14979|go:"GO:0003723"(RNA binding)|reactome:R-HSA-8950505|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034046"("poly(G) binding")|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001193929.1|refseq:NP_112740.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:oOnEEar8AtKO5G6ldehucaRr4kM9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q12906 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-78756|uniprotkb:A8K6F2|uniprotkb:O43409|uniprotkb:Q6P1X1|uniprotkb:Q86XY7|uniprotkb:Q99544|uniprotkb:Q99545|uniprotkb:Q9BZH4|uniprotkb:Q9BZH5|uniprotkb:Q9NQ95|uniprotkb:Q9NQ96|uniprotkb:Q9NQ97|uniprotkb:Q9NQ98|uniprotkb:Q9NQ99|uniprotkb:Q9NQA0|uniprotkb:Q9NQA1|uniprotkb:Q9NQA2|uniprotkb:Q9NRN2|uniprotkb:Q9NRN3|uniprotkb:Q9NRN4|uniprotkb:Q9UMZ9|uniprotkb:Q9UN00|uniprotkb:Q9UN84|uniprotkb:Q9UNA2|ensembl:ENSP00000468156|intact:EBI-10970055|uniprotkb:G5E9M5 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ilf3_human(display_long)|uniprotkb:ILF3(gene name)|psi-mi:ILF3(display_short)|uniprotkb:MPHOSPH4(gene name synonym)|uniprotkb:NF90(gene name synonym)|uniprotkb:Nuclear factor of activated T-cells 90 kDa(gene name synonym)|uniprotkb:Double-stranded RNA-binding protein 76(gene name synonym)|uniprotkb:Translational control protein 80(gene name synonym)|uniprotkb:Nuclear factor associated with dsRNA(gene name synonym)|uniprotkb:M-phase phosphoprotein 4(gene name synonym)|uniprotkb:DRBF(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000129351(gene)|ensembl:ENST00000590261(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051607"(defense response to virus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR033099|interpro:IPR043519|mint:Q12906|rcsb pdb:2L33|rcsb pdb:3P1X|refseq:NP_001131145.1|refseq:NP_004507.2|refseq:NP_036350.2|refseq:NP_060090.2|refseq:NP_703194.1|refseq:XP_016882252.1|refseq:XP_011526286.2|dip:DIP-29853N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:iri+WBUtektANRSCpBO1XBCd9Wk9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:O75569 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-713955|ensembl:ENSP00000318176|uniprotkb:Q53G24|uniprotkb:Q6X7T5|uniprotkb:Q8NDK4|uniprotkb:A8K3I6 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:prkra_human(display_long)|uniprotkb:Protein activator of the interferon-induced protein kinase(gene name synonym)|uniprotkb:PKR-associated protein X(gene name synonym)|uniprotkb:PKR-associating protein X(gene name synonym)|uniprotkb:HSD-14(orf name)|uniprotkb:PRKRA(gene name)|psi-mi:PRKRA(display_short)|uniprotkb:RAX(gene name synonym)|uniprotkb:PACT(gene name synonym)|uniprotkb:HSD14(orf name)|uniprotkb:Protein kinase, interferon-inducible double-stranded RNA-dependent activator(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006955"(immune response)|go:"GO:0008047"(enzyme activator activity)|ensembl:ENSG00000180228(gene)|ensembl:ENST00000325748(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR033363|interpro:IPR044465|interpro:IPR044466|interpro:IPR044467|mint:O75569|rcsb pdb:2DIX|reactome:R-HSA-203927|reactome:R-HSA-426486|refseq:NP_001132989.1|refseq:NP_001132990.1|refseq:NP_003681.1|dip:DIP-41809N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:tZfziopZlC+1d3De97G3kDY+Tog9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P63104 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P05141 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P51991 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1050760|uniprotkb:Q53RW7|uniprotkb:Q6URK5|uniprotkb:D3DPF4|ensembl:ENSP00000376309|ensembl:ENSP00000416340|ensembl:ENSP00000503593|ensembl:ENSP00000504135|ensembl:ENSP00000504152 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:roa3_human(display_long)|uniprotkb:HNRPA3(gene name synonym)|uniprotkb:HNRNPA3(gene name)|psi-mi:HNRNPA3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_919223.1|refseq:NP_001317178.1|ensembl:ENSG00000170144(gene)|ensembl:ENST00000392524(transcript)|ensembl:ENST00000435711(transcript)|ensembl:ENST00000676629(transcript)|ensembl:ENST00000678111(transcript)|ensembl:ENST00000679159(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0051028"(mRNA transport)|go:"GO:0051033"(RNA transmembrane transporter activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034513|interpro:IPR034516|interpro:IPR035979|mint:P51991|reactome:R-HSA-72163|reactome:R-HSA-72203 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:bbg0nIdhEHomcwtgZhT2yHy7+nU9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q92569 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-79893|intact:EBI-28975437|ensembl:ENSP00000262741|ensembl:ENSP00000361075|ensembl:ENSP00000412546|uniprotkb:O60482|uniprotkb:Q5T4P2|uniprotkb:B2R9C1|uniprotkb:Q5T4P1|uniprotkb:D3DQ12 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:p55g_human(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma(gene name synonym)|uniprotkb:PIK3R3(gene name)|psi-mi:PIK3R3(display_short)|uniprotkb:p55PIK(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9670439|ensembl:ENSG00000117461(gene)|ensembl:ENST00000262741(transcript)|ensembl:ENST00000372006(transcript)|ensembl:ENST00000420542(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|interpro:IPR000980(SH2 motif)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR036860|mint:Q92569|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-2219530|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-512988|reactome:R-HSA-6811558|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|reactome:R-HSA-8853659|reactome:R-HSA-9009391|refseq:NP_001107644.1|refseq:NP_003620.3|ensembl:ENSP00000262741|ensembl:ENSP00000361075|ensembl:ENSP00000412546|ensembl:ENST00000423209|ensembl:ENSP00000391431|dip:DIP-30925N|refseq:NP_001290358.1|refseq:XP_016858103.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:oIVTuGRhg/Kn3h+Br1EfiAtiAQQ9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P26599 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-350540|ensembl:ENSP00000014112|intact:EBI-744534|uniprotkb:Q9BUQ0 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ptbp1_human(display_long)|uniprotkb:PTBP1(gene name)|psi-mi:PTBP1(display_short)|uniprotkb:PTB(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein I(gene name synonym)|uniprotkb:57 kDa RNA-binding protein PPTB-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_002810.1|refseq:NP_114367.1|refseq:NP_114368.1|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0016020"(membrane)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0051148"(negative regulation of muscle cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034798|interpro:IPR035000|interpro:IPR035001|interpro:IPR035979|mint:P26599|rcsb pdb:1QM9|rcsb pdb:1SJQ|ensembl:ENSG00000011304(gene)|ensembl:ENST00000349038(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0008380"(RNA splicing)|rcsb pdb:2AD9|rcsb pdb:2ADB|rcsb pdb:2ADC|rcsb pdb:2EVZ|rcsb pdb:2N3O|rcsb pdb:3ZZY|rcsb pdb:3ZZZ|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|rcsb pdb:1SJR - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:fkSnYJELgHxDP0oAQEjBmSX0HIs9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P52597 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352986|ensembl:ENSP00000338477|ensembl:ENSP00000349573|ensembl:ENSP00000400433|ensembl:ENSP00000438061|ensembl:ENSP00000507787|ensembl:ENSP00000348345|uniprotkb:Q5T0N2|uniprotkb:Q96AU2|uniprotkb:B3KM84 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpf_human(display_long)|uniprotkb:HNRNPF(gene name)|psi-mi:HNRNPF(display_short)|uniprotkb:HNRPF(gene name synonym)|uniprotkb:Nucleolin-like protein mcs94-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P52597|rcsb pdb:2HGL|rcsb pdb:2HGM|rcsb pdb:2HGN|rcsb pdb:2KFY|rcsb pdb:2KG0|rcsb pdb:2KG1|rcsb pdb:3TFY|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensembl:ENSG00000169813(gene)|ensembl:ENST00000337970(transcript)|ensembl:ENST00000356053(transcript)|ensembl:ENST00000357065(transcript)|ensembl:ENST00000443950(transcript)|ensembl:ENST00000544000(transcript)|ensembl:ENST00000682386(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001091674.1|refseq:NP_001091675.1|refseq:NP_001091676.1|refseq:NP_001091677.1|refseq:NP_001091678.1|refseq:NP_004957.1|dip:DIP-33145N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:pblzpldZOa5vlZ+zGQY9qyWCxaw9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P46782 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-350569|uniprotkb:Q96BN0|uniprotkb:B2R4T2|ensembl:ENSP00000196551|ensembl:ENSP00000470114|ensembl:ENSP00000472985 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs5_human(display_long)|uniprotkb:RPS5(gene name)|psi-mi:RPS5(display_short)|uniprotkb:Small ribosomal subunit protein uS7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001000.2|rcsb pdb:6OLZ|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6Z6M|rcsb pdb:6XA1|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6Y0G|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:5FLX|rcsb pdb:6OLG|rcsb pdb:6OLI|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72706|ensembl:ENSG00000083845(gene)|ensembl:ENST00000196551(transcript)|ensembl:ENST00000596046(transcript)|ensembl:ENST00000601521(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000235(Ribosomal protein S7)|interpro:IPR005716(Ribosomal protein S7, eukaryotic/archaeal)|interpro:IPR020606|interpro:IPR023798|interpro:IPR036823|mint:P46782|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:5AJ0|reactome:R-HSA-72702 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:SoCJdf2InngZZtlz5qD1k5CEfEo9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q8N163 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|ensembl:ENSP00000310670|ensembl:ENSP00000373930|uniprotkb:B2RB79|uniprotkb:D3DSR6 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_066997.3|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|interpro:IPR028811|mint:Q8N163|reactome:R-HSA-3371453|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|dip:DIP-38122N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P62805 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P09651 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352662|uniprotkb:Q3MIB7|uniprotkb:Q6PJZ7|ensembl:ENSP00000341826|ensembl:ENSP00000503610|uniprotkb:A8K4Z8|intact:EBI-2556572 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:roa1_human(display_long)|uniprotkb:HNRNPA1(gene name)|psi-mi:HNRNPA1(display_short)|uniprotkb:HNRPA1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:Single-strand RNA-binding protein(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_002127.1|refseq:NP_112420.1|ensembl:ENSG00000135486(gene)|ensembl:ENST00000340913(transcript)|ensembl:ENST00000677210(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|rcsb pdb:2LYV|rcsb pdb:2UP1|rcsb pdb:4YOE|rcsb pdb:5MPG|rcsb pdb:5MPL|rcsb pdb:5ZGD|rcsb pdb:5ZGL|rcsb pdb:6BXX|rcsb pdb:6DCL|rcsb pdb:6J60|rcsb pdb:7BX7|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035198"(miRNA binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051170"(import into nucleus)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR034845|interpro:IPR035979|mint:P09651|rcsb pdb:1HA1|rcsb pdb:1L3K|rcsb pdb:1PGZ|rcsb pdb:1PO6|rcsb pdb:1U1K|rcsb pdb:1U1L|rcsb pdb:1U1M|rcsb pdb:1U1N|rcsb pdb:1U1O|rcsb pdb:1U1P|rcsb pdb:1U1Q|rcsb pdb:1U1R|rcsb pdb:1UP1|rcsb pdb:2H4M|refseq:XP_005268883.1|dip:DIP-29338N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:ECXjsLRVtNc/aOw90tEFxowHc6c9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q99729 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P22626 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q07666 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1364|uniprotkb:Q6PJX7|uniprotkb:Q8NB97|uniprotkb:Q99760|uniprotkb:D3DPP3|ensembl:ENSP00000313829 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:khdr1_human(display_long)|uniprotkb:SAM68(gene name synonym)|uniprotkb:Src-associated in mitosis 68 kDa protein(gene name synonym)|uniprotkb:KHDRBS1(gene name)|psi-mi:KHDRBS1(display_short)|uniprotkb:p21 Ras GTPase-activating protein-associated p62(gene name synonym)|uniprotkb:GAP-associated tyrosine phosphoprotein p62(gene name synonym)|uniprotkb:p68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_006550.1|refseq:NP_001258807.1|dip:DIP-29007N|ensembl:ENSG00000121774(gene)|ensembl:ENST00000327300(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0046831"(regulation of RNA export from nucleus)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0070618"(Grb2-Sos complex)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|mint:Q07666|rcsb pdb:2XA6|rcsb pdb:3QHE|reactome:R-HSA-8849468 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:po7jC4Nxu+Aoz6T8K6VRWHp6MKQ9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q9NZI8 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1053892|uniprotkb:C9JT33|ensembl:ENSP00000290341 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:if2b1_human(display_long)|uniprotkb:ZBP1(gene name synonym)|uniprotkb:IGF-II mRNA-binding protein 1(gene name synonym)|uniprotkb:Coding region determinant-binding protein(gene name synonym)|uniprotkb:VICKZ family member 1(gene name synonym)|uniprotkb:IGF2BP1(gene name)|psi-mi:IGF2BP1(display_short)|uniprotkb:Zipcode-binding protein 1(gene name synonym)|uniprotkb:CRDBP(gene name synonym)|uniprotkb:VICKZ1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_006537.3|refseq:NP_001153895.1|ensembl:ENSG00000159217(gene)|ensembl:ENST00000290341(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007399"(nervous system development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010610"(regulation of mRNA stability involved in response to stress)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022013"(pallium cell proliferation in forebrain)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0140059"(dendrite arborization)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034837|interpro:IPR034842|interpro:IPR035979|interpro:IPR036612|mint:Q9NZI8|rcsb pdb:3KRM|rcsb pdb:6QEY|reactome:R-HSA-428359|reactome:R-HSA-5687128|dip:DIP-38139N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:3Ps/PWWYr0WpYcx3G/AOiQEj+vc9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P07437 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q15717 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-374260|uniprotkb:Q9BTT1|ensembl:ENSP00000385269|ensembl:ENSP00000472197|intact:EBI-6190219|uniprotkb:B4DVB8|uniprotkb:Q53XN6 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:elav1_human(display_long)|uniprotkb:ELAVL1(gene name)|psi-mi:ELAVL1(display_short)|uniprotkb:HUR(gene name synonym)|uniprotkb:Hu-antigen R(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 go:"GO:0006606"(protein import into nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035198"(miRNA binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|ensembl:ENSG00000066044(gene)|ensembl:ENST00000407627(transcript)|ensembl:ENST00000596459(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|refseq:NP_001410.2|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR034996|interpro:IPR035979|mint:Q15717|rcsb pdb:3HI9|rcsb pdb:4ED5|rcsb pdb:4EGL|rcsb pdb:4FXV|rcsb pdb:5SZW|rcsb pdb:6G2K|rcsb pdb:6GC5|rcsb pdb:6GD1|rcsb pdb:6GD2|rcsb pdb:6GD3|reactome:R-HSA-450520|reactome:R-HSA-72163|dip:DIP-31291N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:PciL5KuvP+2aUUv9cv7gWScgbw89606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P55265 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-2462104|uniprotkb:B1AQR0|uniprotkb:O15223|uniprotkb:O43859|uniprotkb:O43860|uniprotkb:Q9BYM3|uniprotkb:Q9BYM4|uniprotkb:B1AQQ9|uniprotkb:D3DV76|ensembl:ENSP00000357459 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:dsrad_human(display_long)|uniprotkb:ADAR(gene name)|psi-mi:ADAR(display_short)|uniprotkb:ADAR1(gene name synonym)|uniprotkb:DSRAD(gene name synonym)|uniprotkb:G1P1(gene name synonym)|uniprotkb:IFI4(gene name synonym)|uniprotkb:136 kDa double-stranded RNA-binding protein(gene name synonym)|uniprotkb:K88DSRBP(gene name synonym)|uniprotkb:Interferon-inducible protein 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001020278.1|refseq:NP_001102.2|refseq:NP_001180424.1|refseq:NP_056655.2|refseq:NP_056656.2|refseq:XP_006711174.1|refseq:XP_006711175.1|refseq:XP_006711176.1|dip:DIP-29310N|ensembl:ENSG00000160710(gene)|ensembl:ENST00000368474(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002566"(somatic diversification of immune receptors via somatic mutation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0008251"(tRNA-specific adenosine deaminase activity)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016553"(base conversion or substitution editing)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900369"(negative regulation of RNA interference)|interpro:IPR002466(Adenosine deaminase/editase)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371|interpro:IPR044456|interpro:IPR044457|mint:P55265|rcsb pdb:1QBJ|rcsb pdb:1QGP|rcsb pdb:1XMK|rcsb pdb:2ACJ|rcsb pdb:2GXB|rcsb pdb:2L54|rcsb pdb:2MDR|rcsb pdb:3F21|rcsb pdb:3F22|rcsb pdb:3F23|rcsb pdb:3IRQ|rcsb pdb:3IRR|rcsb pdb:5ZU1|rcsb pdb:5ZUO|rcsb pdb:5ZUP|rcsb pdb:7C0I|reactome:R-HSA-75102|reactome:R-HSA-77042|reactome:R-HSA-909733|go:"GO:0051607"(defense response to virus) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:rP/Yr/h8WLSFNdIuqWnYtZjZ9qI9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:O43143 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q92900 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P31942 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-711437|uniprotkb:Q9NPI4|uniprotkb:Q9UFU4|uniprotkb:Q9Y4J5|uniprotkb:Q9BSX1|uniprotkb:Q9NP53|uniprotkb:Q9NP96|uniprotkb:Q9NPA7|ensembl:ENSP00000265866|uniprotkb:A8K682|uniprotkb:B3KRE1 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrh3_human(display_long)|uniprotkb:HNRNPH3(gene name)|psi-mi:HNRNPH3(display_short)|uniprotkb:HNRPH3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein 2H9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000096746(gene)|ensembl:ENST00000265866(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034969|interpro:IPR034970|interpro:IPR035979|mint:P31942|refseq:NP_036339.1|refseq:NP_067676.2|refseq:NP_001309363.1|refseq:NP_001309365.1|refseq:NP_001309366.1|refseq:NP_001309367.1|refseq:NP_001309368.1|refseq:NP_001309369.1|refseq:NP_001309370.1|refseq:NP_001309374.1|refseq:NP_001309375.1|refseq:NP_001309376.1|refseq:NP_001309377.1|refseq:NP_001309378.1|refseq:XP_016871657.1|refseq:XP_016871658.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:iJGBIhPXnQIIFQmgxWB1WjwVXSY9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q9Y2I1 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-2688731|uniprotkb:Q6PIB4|uniprotkb:Q9UEU4|uniprotkb:Q7L8M3|uniprotkb:Q6PGP3|uniprotkb:Q9UFW3|uniprotkb:Q7Z2X6|uniprotkb:Q9UES6|uniprotkb:C9J245|ensembl:ENSP00000339958|ensembl:ENSP00000418232 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:nisch_human(display_long)|uniprotkb:IRAS(gene name synonym)|uniprotkb:KIAA0975(gene name synonym)|uniprotkb:Imidazoline receptor 1(gene name synonym)|uniprotkb:Imidazoline receptor antisera-selected protein(gene name synonym)|uniprotkb:Imidazoline-1 receptor(gene name synonym)|uniprotkb:Imidazoline-1 receptor candidate protein(gene name synonym)|uniprotkb:NISCH(gene name)|psi-mi:NISCH(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_009115.2|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048243"(norepinephrine secretion)|go:"GO:0055037"(recycling endosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001683(Phox-like)|interpro:IPR032675|interpro:IPR036871|interpro:IPR037904|mint:Q9Y2I1|rcsb pdb:3P0C|reactome:R-HSA-9013149|reactome:R-HSA-9696264|reactome:R-HSA-9696270|ensembl:ENSG00000010322(gene)|ensembl:ENST00000345716(transcript)|ensembl:ENST00000479054(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032228"(regulation of synaptic transmission, GABAergic)|refseq:NP_001263222.1|refseq:NP_001263223.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:GuBgG6MUrD5p1hIhGGmrtCjT0jQ9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P16989 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-358193|uniprotkb:Q14121|uniprotkb:Q969N6|uniprotkb:Q96B76|uniprotkb:B2RBW6|intact:EBI-2560381|ensembl:ENSP00000228251 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ybox3_human(display_long)|uniprotkb:YBX3(gene name)|psi-mi:YBX3(display_short)|uniprotkb:CSDA(gene name synonym)|uniprotkb:Cold shock domain-containing protein A(gene name synonym)|uniprotkb:DBPA(gene name synonym)|uniprotkb:DNA-binding protein A(gene name synonym)|uniprotkb:Single-strand DNA-binding protein NF-GMB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 go:"GO:0046622"(positive regulation of organ growth)|refseq:NP_001138898.1|refseq:NP_003642.3|dip:DIP-42489N|ensembl:ENSG00000060138(gene)|ensembl:ENST00000228251(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008584"(male gonad development)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031267"(small GTPase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:1902219"(negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1905538"(polysome binding)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P16989 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:cWuhmwOBWe5HdgPG1gyN7KzN4Rs9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q12905 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-357925|uniprotkb:A6NDB0|uniprotkb:Q5SR10|uniprotkb:Q5SR11|uniprotkb:Q7L7R3|uniprotkb:Q9BWD4|uniprotkb:Q9P1N0|uniprotkb:B2R8G7|ensembl:ENSP00000355011 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ilf2_human(display_long)|uniprotkb:PRO3063(orf name)|uniprotkb:NF45(gene name synonym)|uniprotkb:ILF2(gene name)|psi-mi:ILF2(display_short)|uniprotkb:Nuclear factor of activated T-cells 45 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_004506.2|refseq:NP_001254738.1|ensembl:ENSG00000143621(gene)|ensembl:ENST00000361891(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR043519|mint:Q12905|reactome:R-HSA-6798695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:HwUDuY6Ev7csoTThxZCW8nJT88o9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:O95793 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-358174|uniprotkb:Q6GTM4|uniprotkb:Q9H5B5|intact:EBI-366174|uniprotkb:Q9H5B4|uniprotkb:Q9Y3Q2|uniprotkb:A8K9Z4|ensembl:ENSP00000360922|uniprotkb:E1P5Y1|uniprotkb:E1P608|uniprotkb:Q5JW29 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:stau1_human(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001309856.1|refseq:NP_001309858.1|refseq:NP_001309859.1|refseq:NP_001032405.1|refseq:NP_004593.2|refseq:NP_059346.2|refseq:NP_059347.2|refseq:NP_059348.2|refseq:NP_001306063.1|refseq:NP_001306064.1|ensembl:ENSG00000124214(gene)|ensembl:ENST00000371856(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|refseq:XP_005260584.1|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:O95793|rcsb pdb:4DKK|rcsb pdb:6HTU|rcsb pdb:6SDW|rcsb pdb:6SDY - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:uYjbWja/hG5M/3likHLe00Z2FgY9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P43243 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352602|ensembl:ENSP00000378284|ensembl:ENSP00000482895|uniprotkb:Q9UHW0|uniprotkb:Q9UQ27|uniprotkb:D3DQC3|uniprotkb:B7ZAV5 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:matr3_human(display_long)|uniprotkb:KIAA0723(gene name synonym)|uniprotkb:MATR3(gene name)|psi-mi:MATR3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000015479(gene)|ensembl:ENST00000394805(transcript)|ensembl:ENST00000618441(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:P43243|refseq:NP_001181883.1|refseq:NP_001181884.1|refseq:NP_061322.2|refseq:NP_954659.1|refseq:NP_001181885.1|refseq:NP_001269207.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:3UZlyCZHgdr1SBgUctv9Ev7XBSQ9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P61981 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-359832|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q6FH52|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSP00000306330 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:1433g_human(display_long)|uniprotkb:YWHAG(gene name)|psi-mi:YWHAG(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_036611.2|ensembl:ENSG00000170027(gene)|ensembl:ENST00000307630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006605"(protein targeting)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61981|rcsb pdb:2B05|rcsb pdb:3UZD|rcsb pdb:4E2E|rcsb pdb:4J6S|rcsb pdb:4O46|rcsb pdb:5D3E|rcsb pdb:6A5S|rcsb pdb:6BYJ|rcsb pdb:6BYL|rcsb pdb:6BZD|rcsb pdb:6FEL|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y4K|rcsb pdb:6Y6B|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-9614399|dip:DIP-33406N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:u1cd71h0RPgTOEMrQVhOelsxWnM9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:O00459 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-346930|uniprotkb:Q5EAT5|uniprotkb:Q9UPH9|intact:EBI-28974273|ensembl:ENSP00000222254 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:p85b_human(display_long)|uniprotkb:PIK3R2(gene name)|psi-mi:PIK3R2(display_short)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSP00000222254|refseq:NP_005018.1|dip:DIP-31811N|ensembl:ENSG00000105647(gene)|ensembl:ENST00000222254(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|rcsb pdb:6OX7|rcsb pdb:6U28|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-186763|reactome:R-HSA-198203|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|mint:O00459|rcsb pdb:2KT1|rcsb pdb:2XS6|rcsb pdb:3MTT|rcsb pdb:3O5Z|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-210993|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9013409 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:Ij0WS0eKPwShgFWQc7OEss7AcAU9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q5JVF3 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1051701|uniprotkb:A6NK09|uniprotkb:Q3ZCX1|uniprotkb:Q5TC57|uniprotkb:Q5TC58|uniprotkb:Q9H7K1|uniprotkb:Q9HBZ7|uniprotkb:Q9NUK6|uniprotkb:Q9NVY1|uniprotkb:Q9NW44|uniprotkb:Q9NWH3|ensembl:ENSP00000337405|ensembl:ENSP00000364626|ensembl:ENSP00000364628 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pcid2_human(display_long)|uniprotkb:CSN12-like protein(gene name synonym)|uniprotkb:PCID2(gene name)|psi-mi:PCID2(display_short)|uniprotkb:HT004(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001120674.1|refseq:NP_001120675.1|refseq:NP_060856.2|refseq:NP_001245142.1|refseq:NP_001307584.1|refseq:NP_001307585.1|refseq:NP_001307586.1|refseq:NP_001307589.1|ensembl:ENSG00000126226(gene)|ensembl:ENST00000337344(transcript)|ensembl:ENST00000375477(transcript)|ensembl:ENST00000375479(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048536"(spleen development)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:2000117"(negative regulation of cysteine-type endopeptidase activity)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|rcsb pdb:3T5X|refseq:XP_016876153.1|dip:DIP-50497N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:jFHv4Xifu2Qw/CzD5SKl3PgJpgE9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P38159 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-743526|ensembl:ENSP00000359645|uniprotkb:Q5JQ67|uniprotkb:Q969R3|uniprotkb:D3DWH0|uniprotkb:E9PG86|uniprotkb:Q8N8Y7|uniprotkb:B4E3U4 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rbmx_human(display_long)|uniprotkb:Glycoprotein p43(gene name synonym)|uniprotkb:RBMX(gene name)|psi-mi:RBMX(display_short)|uniprotkb:HNRPG(gene name synonym)|uniprotkb:RBMXP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000147274(gene)|ensembl:ENST00000320676(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P38159|rcsb pdb:2MB0|rcsb pdb:2MKS|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_002130.2|refseq:NP_001158275.1|dip:DIP-34447N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:ocCkdy9PxjeVLUQf0tMVCEhFfO89606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:O60506 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1024357|uniprotkb:Q53H05|uniprotkb:Q5TCG2|uniprotkb:Q8IW78|uniprotkb:Q8N599|uniprotkb:Q96LC1|uniprotkb:Q96LC2|uniprotkb:Q9Y583|uniprotkb:Q5TCG3|uniprotkb:E1P501|uniprotkb:E1P502|ensembl:ENSP00000358635|ensembl:ENSP00000503783|ensembl:ENSP00000504706 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpq_human(display_long)|uniprotkb:Synaptotagmin-binding, cytoplasmic RNA-interacting protein(gene name synonym)|uniprotkb:Glycine- and tyrosine-rich RNA-binding protein(gene name synonym)|uniprotkb:NS1-associated protein 1(gene name synonym)|uniprotkb:SYNCRIP(gene name)|psi-mi:SYNCRIP(display_short)|uniprotkb:HNRPQ(gene name synonym)|uniprotkb:NSAP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001153145.1|refseq:NP_001153146.1|refseq:NP_001153147.1|refseq:NP_001240700.1|refseq:NP_001153148.1|refseq:NP_001153149.1|refseq:NP_006363.4|ensembl:ENSG00000135316(gene)|ensembl:ENST00000369622(transcript)|ensembl:ENST00000676688(transcript)|ensembl:ENST00000678355(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034544|interpro:IPR034548|interpro:IPR035979|interpro:IPR041337|mint:O60506|rcsb pdb:2DGU|rcsb pdb:2MXT|rcsb pdb:2NBB|rcsb pdb:6KOR|refseq:XP_016865667.1|refseq:XP_005248694.1|dip:DIP-35540N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:2rDkXIp/wWzTOoVtN7Bd3uqZo689606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P23396 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-351193|uniprotkb:Q498B5|uniprotkb:Q8NI95|uniprotkb:B2R7N5|ensembl:ENSP00000433821|ensembl:ENSP00000434643|ensembl:ENSP00000436971|uniprotkb:J3KN86 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs3_human(display_long)|uniprotkb:RPS3(gene name)|psi-mi:RPS3(display_short)|uniprotkb:Small ribosomal subunit protein uS3(gene name synonym)|uniprotkb:OK/SW-cl.26(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_000996.2|ensembl:ENSG00000149273(gene)|ensembl:ENST00000524851(transcript)|ensembl:ENST00000527446(transcript)|ensembl:ENST00000531188(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR004044(K Homology, type 2)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|go:"GO:0071159"(NF-kappaB complex)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR018280|interpro:IPR036419|mint:P23396|rcsb pdb:1WH9|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|rcsb pdb:6QZP|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|refseq:NP_001243731.1|refseq:NP_001247436.1|refseq:NP_001247435.1|dip:DIP-33177N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:fsDW18AMR3YyEEIhMVcngYRWkps9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P14866 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-719024|uniprotkb:Q9H3P3|uniprotkb:A6ND69|uniprotkb:A6NIT8|ensembl:ENSP00000221419|ensembl:ENSP00000489021 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpl_human(display_long)|uniprotkb:HNRPL(gene name synonym)|uniprotkb:HNRNPL(gene name)|psi-mi:HNRNPL(display_short)|uniprotkb:P/OKcl.14(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001005335.1|refseq:NP_001524.2|refseq:XP_011525191.1|ensembl:ENSG00000282947(gene)|ensembl:ENST00000221419(transcript)|ensembl:ENST00000634753(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097157"(pre-mRNA intronic binding)|ensembl:ENSG00000104824(gene)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034816|interpro:IPR034817|interpro:IPR035005|interpro:IPR035008|interpro:IPR035979|mint:P14866|rcsb pdb:3R27|rcsb pdb:3TO8|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:1990904"(ribonucleoprotein complex)|dip:DIP-36355N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:vOfznm03e6Ottg6BptYHmR9qJEc9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P84090 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-711389|uniprotkb:P70659|uniprotkb:Q14259|ensembl:ENSP00000451080|uniprotkb:B2R5H2 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:erh_human(display_long)|uniprotkb:ERH(gene name)|psi-mi:ERH(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000100632(gene)|ensembl:ENST00000557016(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0030496"(midbody)|go:"GO:0034709"(methylosome)|interpro:IPR000781(Enhancer of rudimentary)|interpro:IPR035912|mint:P84090|rcsb pdb:1W9G|rcsb pdb:2NML|rcsb pdb:7CNC|refseq:NP_004441.1|dip:DIP-42473N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:foMOmvZ9wQyH0rrzBB2YlQhrT0g9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q13310 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-372844|uniprotkb:Q6P0N3|uniprotkb:B1ANQ8|ensembl:ENSP00000361948|intact:EBI-877641|uniprotkb:Q4VC03 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pabp4_human(display_long)|uniprotkb:PABPC4(gene name)|psi-mi:PABPC4(display_short)|uniprotkb:APP1(gene name synonym)|uniprotkb:PABP4(gene name synonym)|uniprotkb:"Inducible poly(A)-binding protein"(gene name synonym)|uniprotkb:Activated-platelet protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001129126.1|refseq:NP_003810.1|ensembl:ENSG00000090621(gene)|ensembl:ENST00000372857(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006412"(translation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0061515"(myeloid cell development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:Q13310|refseq:NP_001129125.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:u1qCM3o5X7jLIa1vyqFCIH7v01w9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P31943 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168|ensembl:ENSP00000377082|ensembl:ENSP00000397797|ensembl:ENSP00000492076|ensembl:ENSP00000495786 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_005511.1|refseq:NP_001244222.1|ensembl:ENSG00000169045(gene)|ensembl:ENSG00000284254(gene)|ensembl:ENST00000356731(transcript)|ensembl:ENST00000393432(transcript)|ensembl:ENST00000442819(transcript)|ensembl:ENST00000638505(transcript)|ensembl:ENST00000643310(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q05639 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-354943|ensembl:ENSP00000217182|uniprotkb:P54266|uniprotkb:Q0VGC7|uniprotkb:B5BUF3|uniprotkb:E1P5J1 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ef1a2_human(display_long)|uniprotkb:EEF1A2(gene name)|psi-mi:EEF1A2(display_short)|uniprotkb:EEF1AL(gene name synonym)|uniprotkb:STN(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-2(gene name synonym)|uniprotkb:Statin-S1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000101210(gene)|ensembl:ENST00000217182(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0090218"(positive regulation of lipid kinase activity)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:Q05639|rcsb pdb:3C5J|reactome:R-HSA-156842|refseq:NP_001949.1|dip:DIP-40060N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:vFXfcSRokxKo5RW0tRE1qEK0NKw9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q15366 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|uniprotkb:B4DXP5|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|ensembl:ENSP00000408949 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|dip:DIP-58934N|ensembl:ENSG00000197111(gene)|ensembl:ENST00000439930(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P12236 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-356254|ensembl:ENSP00000370808|uniprotkb:Q96C49 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000169100(gene)|ensembl:ENST00000381401(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|refseq:NP_001627.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P42336 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-2116585|uniprotkb:Q14CW1|uniprotkb:Q99762|ensembl:ENSP00000263967 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pk3ca_human(display_long)|uniprotkb:Phosphoinositide-3-kinase catalytic alpha polypeptide(gene name synonym)|uniprotkb:Serine/threonine protein kinase PIK3CA(gene name synonym)|uniprotkb:PIK3CA(gene name)|psi-mi:PIK3CA(display_short)|uniprotkb:Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha(gene name synonym)|uniprotkb:Phosphoinositide 3-kinase alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:XP_011511196.1|refseq:XP_006713721.1|refseq:NP_006209.2|dip:DIP-42728N|ensembl:ENSG00000121879(gene)|ensembl:ENST00000263967(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001944"(vasculature development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0005944"(phosphatidylinositol 3-kinase complex, class IB)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006909"(phagocytosis)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030168"(platelet activation)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035004"(phosphatidylinositol 3-kinase activity)|go:"GO:0035005"(1-phosphatidylinositol-4-phosphate 3-kinase activity)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0038028"(insulin receptor signaling pathway via phosphatidylinositol 3-kinase)|go:"GO:0038084"(vascular endothelial growth factor signaling pathway)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0043276"(anoikis)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044029"(hypomethylation of CpG island)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046934"(phosphatidylinositol-4,5-bisphosphate 3-kinase activity)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110053"(regulation of actin filament organization)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR000341(Phosphoinositide 3-kinase, ras-binding)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR003113(Phosphatidylinositol 3-kinase, p85-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR029071|interpro:IPR035892|interpro:IPR036940|interpro:IPR037704|interpro:IPR042236|mint:P42336|rcsb pdb:2ENQ|rcsb pdb:2RD0|rcsb pdb:3HHM|rcsb pdb:3HIZ|rcsb pdb:3ZIM|rcsb pdb:4JPS|rcsb pdb:4L1B|rcsb pdb:4L23|rcsb pdb:4L2Y|rcsb pdb:4OVU|rcsb pdb:4OVV|rcsb pdb:4TUU|rcsb pdb:4TV3|rcsb pdb:4WAF|rcsb pdb:4YKN|rcsb pdb:4ZOP|rcsb pdb:5DXT|rcsb pdb:5FI4|rcsb pdb:5ITD|rcsb pdb:5SW8|rcsb pdb:5SWG|rcsb pdb:5SWO|rcsb pdb:5SWP|rcsb pdb:5SWR|rcsb pdb:5SWT|rcsb pdb:5SX8|rcsb pdb:5SX9|rcsb pdb:5SXA|rcsb pdb:5SXB|rcsb pdb:5SXC|rcsb pdb:5SXD|rcsb pdb:5SXE|rcsb pdb:5SXF|rcsb pdb:5SXI|rcsb pdb:5SXJ|rcsb pdb:5SXK|rcsb pdb:5UBR|rcsb pdb:5UK8|rcsb pdb:5UKJ|rcsb pdb:5UL1|rcsb pdb:5XGH|rcsb pdb:5XGI|rcsb pdb:5XGJ|rcsb pdb:6GVF|rcsb pdb:6GVG|rcsb pdb:6GVH|rcsb pdb:6GVI|rcsb pdb:6NCT|rcsb pdb:6OAC|rcsb pdb:6PYS|rcsb pdb:6VO7|rcsb pdb:7JIU|rcsb pdb:7K6M|rcsb pdb:7K6N|rcsb pdb:7K6O|rcsb pdb:7K71|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1236382|reactome:R-HSA-1250342|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-180292|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-1963642|reactome:R-HSA-198203|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654689|reactome:R-HSA-5654695|reactome:R-HSA-5654710|reactome:R-HSA-5654720|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-9009391|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9027276|reactome:R-HSA-9028335|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9603381|reactome:R-HSA-9607240|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|rcsb pdb:5DXH|reactome:R-HSA-9703465|reactome:R-HSA-9703648 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:YIZWt9VfCmyBCWYkqAEaMAEsl3w9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q9UKM9 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-714796|uniprotkb:Q14621|uniprotkb:Q2M365|uniprotkb:Q5QPL8|uniprotkb:Q9BQX6|uniprotkb:Q9UJE3|ensembl:ENSP00000246194 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:raly_human(display_long)|uniprotkb:hnRNP associated with lethal yellow protein homolog(gene name synonym)|uniprotkb:Autoantigen p542(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein C-like 2(gene name synonym)|uniprotkb:RALY(gene name)|psi-mi:RALY(display_short)|uniprotkb:P542(gene name synonym)|uniprotkb:HNRPCL2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:XP_011526996.1|refseq:XP_011526997.1|ensembl:ENSG00000125970(gene)|ensembl:ENST00000246194(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903506"(regulation of nucleic acid-templated transcription)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR034502|interpro:IPR035979|mint:Q9UKM9|rcsb pdb:1WF1|refseq:NP_031393.2|refseq:NP_057951.1|refseq:XP_005260391.1|refseq:XP_005260393.1|refseq:XP_016883220.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:3hd0n2UW0FSRNvSJa2mqflVeorc9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P27348 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081|ensembl:ENSP00000371267 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_006817.1|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|ensembl:ENSG00000134308(gene)|ensembl:ENST00000238081(transcript)|ensembl:ENST00000381844(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|dip:DIP-27584N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q8WWM7 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-948363|ensembl:ENSP00000338718|uniprotkb:O95135|uniprotkb:Q6NVJ8|uniprotkb:Q6PJW6|uniprotkb:Q8IU61|uniprotkb:Q8IU95|uniprotkb:Q8WWM3|uniprotkb:Q8WWM4|uniprotkb:Q8WWM5|uniprotkb:Q8WWM6|uniprotkb:Q99703|uniprotkb:B9EGM2|uniprotkb:E9PAR9|uniprotkb:A8K1R6|uniprotkb:Q63ZY4 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:atx2l_human(display_long)|uniprotkb:Ataxin-2 domain protein(gene name synonym)|uniprotkb:Ataxin-2-related protein(gene name synonym)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short)|uniprotkb:A2D(gene name synonym)|uniprotkb:A2LG(gene name synonym)|uniprotkb:A2LP(gene name synonym)|uniprotkb:A2RP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000168488(gene)|ensembl:ENST00000336783(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045296"(cadherin binding)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR025852|mint:Q8WWM7|refseq:NP_009176.2|refseq:NP_663760.1|refseq:NP_680780.1|refseq:NP_680781.1|refseq:XP_005255123.1|refseq:NP_059867.3|refseq:NP_680782.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:t7lrS10IM/5pt+rrbqBRowZ6b+09606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P62258 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:O14654 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-356594|ensembl:ENSP00000505547 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q3BBV2 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-2863585|intact:EBI-28968706 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:nbpf8_human(display_long)|uniprotkb:NBPF8(gene name)|psi-mi:NBPF8(display_short)|uniprotkb:NBPF8P(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 interpro:IPR010630(Protein of unknown function DUF1220)|go:"GO:0005737"(cytoplasm) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:MNZ5h3PahJhkjpbb8el5/n+HVDE9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P61978 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-304185|intact:EBI-28971491|ensembl:ENSP00000317788|ensembl:ENSP00000353552|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q59F98|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62|uniprotkb:Q5T6W4|intact:EBI-3440248|uniprotkb:Q6IBN1 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpk_human(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000165119(gene)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000351839(transcript)|ensembl:ENST00000360384(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0002102"(podosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61978|rcsb pdb:1J5K|rcsb pdb:1KHM|rcsb pdb:1ZZI|rcsb pdb:1ZZJ|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9610379|rcsb pdb:1ZZK|refseq:NP_002131.2|refseq:NP_112552.1|refseq:NP_112553.1|ensembl:ENSP00000317788|ensembl:ENSP00000353552|ensembl:ENST00000376263|ensembl:ENSP00000365439|ensembl:ENST00000376281|ensembl:ENSP00000365458|refseq:NP_001305115.1|refseq:NP_001305116.1|refseq:NP_001305117.1|refseq:XP_016870157.1|refseq:XP_005252017.1|refseq:XP_005252020.1|refseq:XP_005252022.1|dip:DIP-31805N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P67809 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:O43390 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-713419|uniprotkb:S4R3J4|uniprotkb:Q5TEH1|ensembl:ENSP00000304405|ensembl:ENSP00000363741|ensembl:ENSP00000489252|ensembl:ENSP00000489371|uniprotkb:Q9BV64|uniprotkb:Q2L7G6 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpr_human(display_long)|uniprotkb:HNRPR(gene name synonym)|uniprotkb:HNRNPR(gene name)|psi-mi:HNRNPR(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001095868.1|refseq:XP_005245768.1|ensembl:ENSG00000125944(gene)|ensembl:ENSG00000282958(gene)|ensembl:ENST00000302271(transcript)|ensembl:ENST00000374612(transcript)|ensembl:ENST00000634263(transcript)|ensembl:ENST00000634766(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043679"(axon terminus)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034411|interpro:IPR035979|mint:O43390|rcsb pdb:2DK2|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR041337|refseq:NP_005817.1|refseq:XP_011538773.1|refseq:NP_001284549.1|refseq:XP_016855497.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:UiOaRbnMd1S2FthR4RWltyq6xT49606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P27986 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-79464|intact:EBI-28974553|ensembl:ENSP00000428056|ensembl:ENSP00000429277|uniprotkb:Q15747|uniprotkb:Q4VBZ7|uniprotkb:Q53EM6|uniprotkb:Q8IXA2|uniprotkb:Q8N1C5|uniprotkb:D3DWA0|uniprotkb:B3KT19|uniprotkb:E7EX19 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:p85a_human(display_long)|uniprotkb:PIK3R1(gene name)|psi-mi:PIK3R1(display_short)|uniprotkb:GRB1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001229395.1|refseq:NP_852556.2|refseq:NP_852664.1|refseq:NP_852665.1|ensembl:ENSG00000145675(gene)|ensembl:ENST00000521381(transcript)|ensembl:ENST00000521657(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|ensembl:ENST00000320694|ensembl:ENSP00000323512|ensembl:ENST00000336483|ensembl:ENSP00000338554|ensembl:ENSP00000428056|ensembl:ENSP00000429277|ensembl:ENST00000523872|ensembl:ENSP00000430098|rcsb pdb:5SXA|rcsb pdb:5SXB|rcsb pdb:5SXC|rcsb pdb:5SXD|rcsb pdb:5SXE|rcsb pdb:5SXF|rcsb pdb:5SXI|rcsb pdb:5SXJ|rcsb pdb:5SXK|rcsb pdb:5UBT|rcsb pdb:5UK8|rcsb pdb:5UKJ|rcsb pdb:5SX9|rcsb pdb:5UL1|rcsb pdb:5VLR|rcsb pdb:5XGH|rcsb pdb:5XGI|rcsb pdb:5XGJ|rcsb pdb:6NCT|rcsb pdb:6PYR|rcsb pdb:6PYU|reactome:R-HSA-1660499|rcsb pdb:7CIO|rcsb pdb:7LM2|reactome:R-HSA-180292|reactome:R-HSA-109704|reactome:R-HSA-1839117|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1236382|reactome:R-HSA-186763|reactome:R-HSA-1963642|reactome:R-HSA-1250342|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-198203|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-1433557|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-430116|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654689|reactome:R-HSA-5654695|reactome:R-HSA-5654710|reactome:R-HSA-5654720|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9603381|reactome:R-HSA-9607240|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-983695|reactome:R-HSA-5655253|reactome:R-HSA-5655302|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-6811558|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-5655291|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9027276|reactome:R-HSA-9028335|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0043559"(insulin binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1990578"(perinuclear endoplasmic reticulum membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035591|interpro:IPR036028|interpro:IPR036860|interpro:IPR044124|mint:P27986|rcsb pdb:1A0N|rcsb pdb:1AZG|rcsb pdb:1H9O|rcsb pdb:1PBW|rcsb pdb:1PHT|rcsb pdb:1PIC|rcsb pdb:1PKS|rcsb pdb:1PKT|rcsb pdb:2IUG|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|rcsb pdb:2IUH|rcsb pdb:2IUI|rcsb pdb:2RD0|rcsb pdb:3HHM|rcsb pdb:3HIZ|rcsb pdb:3I5R|rcsb pdb:3I5S|rcsb pdb:4A55|rcsb pdb:4JPS|rcsb pdb:4L1B|rcsb pdb:4L23|rcsb pdb:4L2Y|rcsb pdb:4OVU|rcsb pdb:4OVV|rcsb pdb:4WAF|rcsb pdb:4YKN|rcsb pdb:4ZOP|rcsb pdb:5AUL|rcsb pdb:5FI4|rcsb pdb:5GJI|rcsb pdb:5ITD|rcsb pdb:5M6U|rcsb pdb:5SW8|rcsb pdb:5SWG|rcsb pdb:5SWO|rcsb pdb:2V1Y|rcsb pdb:5SWP|rcsb pdb:5SWR|rcsb pdb:5SWT|rcsb pdb:5SX8|refseq:XP_016865074.1|refseq:XP_005248599.1|dip:DIP-119N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:pANLtVCSWVr64OXaS6bCjGBwfig9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P11940 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P07910 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-357966|uniprotkb:P22628|uniprotkb:Q53EX2|uniprotkb:Q59FD3|uniprotkb:Q5FWE8|uniprotkb:Q86SF8|uniprotkb:Q86U45|uniprotkb:Q96HK7|uniprotkb:Q96HM4|uniprotkb:Q96IY5|uniprotkb:Q9BTS3|uniprotkb:D3DS19|uniprotkb:D3DS22|intact:EBI-28976506|ensembl:ENSP00000404848|ensembl:ENSP00000451291|ensembl:ENSP00000452276 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpc_human(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001070910.1|refseq:NP_001070911.1|refseq:NP_004491.2|refseq:NP_112604.2|ensembl:ENSP00000404848|ensembl:ENST00000430246|ensembl:ENSP00000442816|ensembl:ENST00000553300|ensembl:ENSP00000450544|ensembl:ENSP00000451291|ensembl:ENST00000554969|ensembl:ENSP00000452276|ensembl:ENSP00000450725|ensembl:ENST00000555883|ensembl:ENSP00000450629|ensembl:ENST00000556628|ensembl:ENSP00000451652|ensembl:ENST00000556897|ensembl:ENSP00000451176|refseq:XP_011535010.1|refseq:XP_011535011.1|refseq:XP_011535012.1|refseq:XP_011535013.1|refseq:XP_011535014.1|refseq:XP_016876741.1|refseq:XP_016876742.1|dip:DIP-29854N|refseq:XP_006720188.1|ensembl:ENSG00000092199(gene)|ensembl:ENST00000420743(transcript)|ensembl:ENST00000554455(transcript)|ensembl:ENST00000557201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979|mint:P07910|rcsb pdb:1TXP|rcsb pdb:1WF2|rcsb pdb:2MXY|rcsb pdb:2MZ1|rcsb pdb:3LN4|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:Fj5tiH0wrNUjTnsURIg8dB8laMg9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P42338 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-2609540|uniprotkb:D3DNF0|uniprotkb:Q24JU2|ensembl:ENSP00000289153|ensembl:ENSP00000418143|ensembl:ENSP00000501150 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pk3cb_human(display_long)|uniprotkb:PIK3CB(gene name)|psi-mi:PIK3CB(display_short)|uniprotkb:PIK3C1(gene name synonym)|uniprotkb:Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_006210.1|refseq:XP_011511197.1|refseq:XP_005247587.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0030168"(platelet activation)|go:"GO:0030496"(midbody)|go:"GO:0033031"(positive regulation of neutrophil apoptotic process)|go:"GO:0035004"(phosphatidylinositol 3-kinase activity)|go:"GO:0035005"(1-phosphatidylinositol-4-phosphate 3-kinase activity)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046934"(phosphatidylinositol-4,5-bisphosphate 3-kinase activity)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0070527"(platelet aggregation)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR000341(Phosphoinositide 3-kinase, ras-binding)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR003113(Phosphatidylinositol 3-kinase, p85-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR029071|interpro:IPR035892|interpro:IPR036940|interpro:IPR037702|interpro:IPR042236|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1660499|reactome:R-HSA-186763|reactome:R-HSA-198203|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8853659|reactome:R-HSA-9027276|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9673767|reactome:R-HSA-9673770|ensembl:ENSG00000051382(gene)|ensembl:ENST00000289153(transcript)|ensembl:ENST00000477593(transcript)|ensembl:ENST00000674063(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001952"(regulation of cell-matrix adhesion)|go:"GO:0002931"(response to ischemia)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_006713722.1|refseq:XP_016862108.1|dip:DIP-44775N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:Nga6TlSCXWs2NVRR5XfxvnLfWUk9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P46783 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-354442|uniprotkb:Q5TZC0|uniprotkb:B2R4E3|ensembl:ENSP00000481646|ensembl:ENSP00000494190|ensembl:ENSP00000494440|ensembl:ENSP00000497917 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs10_human(display_long)|uniprotkb:RPS10(gene name)|psi-mi:RPS10(display_short)|uniprotkb:Small ribosomal subunit protein eS10(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001005.1|refseq:NP_001190174.1|refseq:NP_001191020.1|ensembl:ENSG00000124614(gene)|ensembl:ENST00000464218(transcript)|ensembl:ENST00000467531(transcript)|ensembl:ENST00000621356(transcript)|ensembl:ENST00000648437(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR005326(Plectin/S10, N-terminal)|rcsb pdb:6G51|interpro:IPR036388|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|interpro:IPR037447|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|mint:P46783|rcsb pdb:4UG0|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:4V6X|rcsb pdb:6ZUO|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|rcsb pdb:5T2C|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:GWUAJh7s0w/ar/SOpx0hiIJOr2c9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P05386 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-354582|uniprotkb:A6NIB2|ensembl:ENSP00000346037 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rla1_human(display_long)|uniprotkb:RPLP1(gene name)|psi-mi:RPLP1(display_short)|uniprotkb:RRP1(gene name synonym)|uniprotkb:Large ribosomal subunit protein P1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_000994.1|refseq:NP_998890.1|ensembl:ENSG00000137818(gene)|ensembl:ENST00000260379(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR027534|interpro:IPR038716|mint:P05386|rcsb pdb:2LBF|rcsb pdb:4BEH|rcsb pdb:4V6X|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:rHSXz4ZCJy+JH6OrjUgHiTK85mo9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q9BUJ2 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1018153|uniprotkb:O76022|uniprotkb:Q6ZSZ0|uniprotkb:Q7L8P4|uniprotkb:Q8N6Z4|uniprotkb:Q96G37|uniprotkb:Q9HAL3|uniprotkb:Q9UG75|intact:EBI-3183399|intact:EBI-2339292|uniprotkb:B3KMW7|ensembl:ENSP00000375863|intact:EBI-2563529 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrl1_human(display_long)|uniprotkb:E1BAP5(gene name synonym)|uniprotkb:HNRNPUL1(gene name)|psi-mi:HNRNPUL1(display_short)|uniprotkb:HNRPUL1(gene name synonym)|uniprotkb:Adenovirus early region 1B-associated protein 5(gene name synonym)|uniprotkb:E1B-55 kDa-associated protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_008971.2|refseq:NP_653333.1|go:"GO:0009615"(response to virus)|go:"GO:0019899"(enzyme binding)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027025|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q9BUJ2|reactome:R-HSA-72163|ensembl:ENSG00000105323(gene)|ensembl:ENST00000392006(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|refseq:NP_001308140.1|refseq:NP_001308137.1|dip:DIP-39419N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:IahA7SVR1NmvldrWKQlAwApinQE9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P31946 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P62847 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-354515|uniprotkb:P16632|uniprotkb:Q7Z3D1|uniprotkb:Q5T0P7|uniprotkb:Q5T0P8|uniprotkb:E7EPK6|ensembl:ENSP00000478869 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs24_human(display_long)|uniprotkb:RPS24(gene name)|psi-mi:RPS24(display_short)|uniprotkb:Small ribosomal subunit protein eS24(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001135757.1|refseq:NP_001017.1|refseq:NP_001135755.1|refseq:NP_148982.1|ensembl:ENSG00000138326(gene)|ensembl:ENST00000613865(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR001976(Ribosomal protein S24e)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR018098|mint:P62847|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6XA1|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:M/qkRxabHx9PFaOM7EwKDOOwu7Q9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q9NNW5 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1568315|uniprotkb:B4DHK2|uniprotkb:Q3MIT1|uniprotkb:Q9UF63|ensembl:ENSP00000477389 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:wdr6_human(display_long)|uniprotkb:WDR6(gene name)|psi-mi:WDR6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_060501.3|refseq:NP_001307475.1|refseq:NP_001307476.1|ensembl:ENSG00000178252(gene)|ensembl:ENST00000608424(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0030488"(tRNA methylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9NNW5|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:gYSDkyuDdKhj387/1P3bhpKJXy89606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q08211 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352022|intact:EBI-1058470|uniprotkb:Q5VY62|uniprotkb:Q6PD69|uniprotkb:Q99556|uniprotkb:B2RNV4|uniprotkb:Q05CI5|uniprotkb:Q12803|uniprotkb:Q32Q22|ensembl:ENSP00000356520 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:dhx9_human(display_long)|uniprotkb:DHX9(gene name)|psi-mi:DHX9(display_short)|uniprotkb:DDX9(gene name synonym)|uniprotkb:NDH2(gene name synonym)|uniprotkb:DExH-box helicase 9(gene name synonym)|uniprotkb:RNA helicase A(gene name synonym)|uniprotkb:LKP(gene name synonym)|uniprotkb:Nuclear DNA helicase II(gene name synonym)|uniprotkb:DEAH box protein 9(gene name synonym)|uniprotkb:Leukophysin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154589|imex:IM-17331-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001348.2|dip:DIP-31504N|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033679"(3'-5' DNA/RNA helicase activity)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045142"(triplex DNA binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0097165"(nuclear stress granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1905172"(RISC complex binding)|go:"GO:1905538"(polysome binding)|go:"GO:1905698"(positive regulation of polysome binding)|go:"GO:1990518"(single-stranded 3'-5' DNA helicase activity)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000765"(regulation of cytoplasmic translation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR044445|interpro:IPR044446|interpro:IPR044447|mint:Q08211|rcsb pdb:3LLM|rcsb pdb:3VYX|rcsb pdb:3VYY|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-72163|go:"GO:1904973"(positive regulation of viral translation)|ensembl:ENSG00000135829(gene)|ensembl:ENST00000367549(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006260"(DNA replication)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0016604"(nuclear body) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:b0VP2Frtvwa9WbYVMwB6TbV2uGU9606 intact-crc:1349079233B8AC8E|rigid:EqrPey4WdF8HCnUlbkFbbDxqI4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMX2 uniprotkb:Q7L7L0 intact:EBI-710918 intact:EBI-5325551|ensembl:ENSP00000355656|ensembl:ENSP00000493926|uniprotkb:B2R4S4 psi-mi:polg_hcvco(display_long) psi-mi:h2a3_human(display_long)|uniprotkb:H2AW(gene name)|psi-mi:H2AW(display_short)|uniprotkb:HIST3H2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154835|imex:IM-17331-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0039690"(positive stranded viral RNA replication)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0075519"(microtubule-dependent intracellular transport of viral material)|go:"GO:0075520"(actin-dependent intracellular transport of virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1ZH1|rcsb pdb:2JY0|rcsb pdb:2KWT|rcsb pdb:2KWZ|rcsb pdb:3FQL|rcsb pdb:3FQM|rcsb pdb:3FQQ|rcsb pdb:3KN2|rcsb pdb:3KQH|rcsb pdb:3KQK|rcsb pdb:3KQL|rcsb pdb:3KQN|rcsb pdb:3KQU|rcsb pdb:3Q0Z|rcsb pdb:3QGD|rcsb pdb:3QGE|rcsb pdb:3QGF|rcsb pdb:3QGG|rcsb pdb:4NLD|rcsb pdb:4U01|go:"GO:0032991"(protein-containing complex)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0003723"(RNA binding)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003779"(actin binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5E4F|rcsb pdb:5PZK|rcsb pdb:5PZL|rcsb pdb:5PZM|rcsb pdb:5PZN|rcsb pdb:5PZO|rcsb pdb:5PZP|rcsb pdb:5TRH|rcsb pdb:5TRI|rcsb pdb:5TRJ|rcsb pdb:5TRK|rcsb pdb:5TWN|interpro:IPR042205|interpro:IPR042209|interpro:IPR043128|interpro:IPR027417|mint:Q9WMX2|interpro:IPR038170|interpro:IPR038568|interpro:IPR043502|interpro:IPR043504 ensembl:ENSG00000181218(gene)|ensembl:ENSG00000284841(gene)|ensembl:ENST00000366695(transcript)|refseq:NP_254280.1|ensembl:ENST00000645741(transcript)|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-5689603|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q7L7L0|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000786"(nucleosome)|dip:DIP-48936N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:3GilwqS4csV8LvvR72ulHAcle3A333284 rogid:t0RdR1SmUtmwRjtCS3uTyLGqSUI9606 intact-crc:6EAC8F648749E980 false sufficient binding region:2-191|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMX2 uniprotkb:P20671 intact:EBI-710918 intact:EBI-4407441|uniprotkb:A0PK91|uniprotkb:P57754|uniprotkb:Q6FGY6|ensembl:ENSP00000341094 psi-mi:polg_hcvco(display_long) psi-mi:h2a1d_human(display_long)|uniprotkb:H2AC7(gene name)|psi-mi:H2AC7(display_short)|uniprotkb:H2AFG(gene name synonym)|uniprotkb:HIST1H2AD(gene name synonym)|uniprotkb:Histone H2A.3(gene name synonym)|uniprotkb:Histone H2A/g(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154835|imex:IM-17331-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0039690"(positive stranded viral RNA replication)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0075519"(microtubule-dependent intracellular transport of viral material)|go:"GO:0075520"(actin-dependent intracellular transport of virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1ZH1|rcsb pdb:2JY0|rcsb pdb:2KWT|rcsb pdb:2KWZ|rcsb pdb:3FQL|rcsb pdb:3FQM|rcsb pdb:3FQQ|rcsb pdb:3KN2|rcsb pdb:3KQH|rcsb pdb:3KQK|rcsb pdb:3KQL|rcsb pdb:3KQN|rcsb pdb:3KQU|rcsb pdb:3Q0Z|rcsb pdb:3QGD|rcsb pdb:3QGE|rcsb pdb:3QGF|rcsb pdb:3QGG|rcsb pdb:4NLD|rcsb pdb:4U01|go:"GO:0032991"(protein-containing complex)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0003723"(RNA binding)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003779"(actin binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5E4F|rcsb pdb:5PZK|rcsb pdb:5PZL|rcsb pdb:5PZM|rcsb pdb:5PZN|rcsb pdb:5PZO|rcsb pdb:5PZP|rcsb pdb:5TRH|rcsb pdb:5TRI|rcsb pdb:5TRJ|rcsb pdb:5TRK|rcsb pdb:5TWN|interpro:IPR042205|interpro:IPR042209|interpro:IPR043128|interpro:IPR027417|mint:Q9WMX2|interpro:IPR038170|interpro:IPR038568|interpro:IPR043502|interpro:IPR043504 refseq:NP_066409.1|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000196866(gene)|ensembl:ENST00000341023(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:5GT3|rcsb pdb:6KBB|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:3GilwqS4csV8LvvR72ulHAcle3A333284 rogid:Geraq+dGw3pvAAhgzzXQnYxDOOw9606 intact-crc:6EAC8F648749E980 false sufficient binding region:2-191|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMX2 uniprotkb:P55795 intact:EBI-710918 intact:EBI-352823|ensembl:ENSP00000361927|uniprotkb:Q9HHA7|uniprotkb:A1L400 psi-mi:polg_hcvco(display_long) psi-mi:hnrh2_human(display_long)|uniprotkb:HNRNPH2(gene name)|psi-mi:HNRNPH2(display_short)|uniprotkb:FTP3(gene name synonym)|uniprotkb:HNRPH2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein H'(gene name synonym)|uniprotkb:FTP-3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154835|imex:IM-17331-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0039690"(positive stranded viral RNA replication)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0075519"(microtubule-dependent intracellular transport of viral material)|go:"GO:0075520"(actin-dependent intracellular transport of virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1ZH1|rcsb pdb:2JY0|rcsb pdb:2KWT|rcsb pdb:2KWZ|rcsb pdb:3FQL|rcsb pdb:3FQM|rcsb pdb:3FQQ|rcsb pdb:3KN2|rcsb pdb:3KQH|rcsb pdb:3KQK|rcsb pdb:3KQL|rcsb pdb:3KQN|rcsb pdb:3KQU|rcsb pdb:3Q0Z|rcsb pdb:3QGD|rcsb pdb:3QGE|rcsb pdb:3QGF|rcsb pdb:3QGG|rcsb pdb:4NLD|rcsb pdb:4U01|go:"GO:0032991"(protein-containing complex)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0003723"(RNA binding)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003779"(actin binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5E4F|rcsb pdb:5PZK|rcsb pdb:5PZL|rcsb pdb:5PZM|rcsb pdb:5PZN|rcsb pdb:5PZO|rcsb pdb:5PZP|rcsb pdb:5TRH|rcsb pdb:5TRI|rcsb pdb:5TRJ|rcsb pdb:5TRK|rcsb pdb:5TWN|interpro:IPR042205|interpro:IPR042209|interpro:IPR043128|interpro:IPR027417|mint:Q9WMX2|interpro:IPR038170|interpro:IPR038568|interpro:IPR043502|interpro:IPR043504 ensembl:ENSG00000126945(gene)|ensembl:ENST00000316594(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P55795|rcsb pdb:1WEZ|rcsb pdb:1WG5|rcsb pdb:6DG1|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001027565.1|refseq:NP_062543.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:3GilwqS4csV8LvvR72ulHAcle3A333284 rogid:811j5syFsbk/QSaZv/ag9QsFUEQ9606 intact-crc:6EAC8F648749E980 false sufficient binding region:2-191|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMX2 uniprotkb:P31942 intact:EBI-710918 intact:EBI-711437|uniprotkb:Q9NPI4|uniprotkb:Q9UFU4|uniprotkb:Q9Y4J5|uniprotkb:Q9BSX1|uniprotkb:Q9NP53|uniprotkb:Q9NP96|uniprotkb:Q9NPA7|ensembl:ENSP00000265866|uniprotkb:A8K682|uniprotkb:B3KRE1 psi-mi:polg_hcvco(display_long) psi-mi:hnrh3_human(display_long)|uniprotkb:HNRNPH3(gene name)|psi-mi:HNRNPH3(display_short)|uniprotkb:HNRPH3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein 2H9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154835|imex:IM-17331-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0039690"(positive stranded viral RNA replication)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0075519"(microtubule-dependent intracellular transport of viral material)|go:"GO:0075520"(actin-dependent intracellular transport of virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1ZH1|rcsb pdb:2JY0|rcsb pdb:2KWT|rcsb pdb:2KWZ|rcsb pdb:3FQL|rcsb pdb:3FQM|rcsb pdb:3FQQ|rcsb pdb:3KN2|rcsb pdb:3KQH|rcsb pdb:3KQK|rcsb pdb:3KQL|rcsb pdb:3KQN|rcsb pdb:3KQU|rcsb pdb:3Q0Z|rcsb pdb:3QGD|rcsb pdb:3QGE|rcsb pdb:3QGF|rcsb pdb:3QGG|rcsb pdb:4NLD|rcsb pdb:4U01|go:"GO:0032991"(protein-containing complex)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0003723"(RNA binding)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003779"(actin binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5E4F|rcsb pdb:5PZK|rcsb pdb:5PZL|rcsb pdb:5PZM|rcsb pdb:5PZN|rcsb pdb:5PZO|rcsb pdb:5PZP|rcsb pdb:5TRH|rcsb pdb:5TRI|rcsb pdb:5TRJ|rcsb pdb:5TRK|rcsb pdb:5TWN|interpro:IPR042205|interpro:IPR042209|interpro:IPR043128|interpro:IPR027417|mint:Q9WMX2|interpro:IPR038170|interpro:IPR038568|interpro:IPR043502|interpro:IPR043504 ensembl:ENSG00000096746(gene)|ensembl:ENST00000265866(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034969|interpro:IPR034970|interpro:IPR035979|mint:P31942|refseq:NP_036339.1|refseq:NP_067676.2|refseq:NP_001309363.1|refseq:NP_001309365.1|refseq:NP_001309366.1|refseq:NP_001309367.1|refseq:NP_001309368.1|refseq:NP_001309369.1|refseq:NP_001309370.1|refseq:NP_001309374.1|refseq:NP_001309375.1|refseq:NP_001309376.1|refseq:NP_001309377.1|refseq:NP_001309378.1|refseq:XP_016871657.1|refseq:XP_016871658.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:3GilwqS4csV8LvvR72ulHAcle3A333284 rogid:iJGBIhPXnQIIFQmgxWB1WjwVXSY9606 intact-crc:6EAC8F648749E980 false sufficient binding region:2-191|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMX2 uniprotkb:P0C0S8 intact:EBI-710918 intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538 psi-mi:polg_hcvco(display_long) psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154835|imex:IM-17331-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0039690"(positive stranded viral RNA replication)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0075519"(microtubule-dependent intracellular transport of viral material)|go:"GO:0075520"(actin-dependent intracellular transport of virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1ZH1|rcsb pdb:2JY0|rcsb pdb:2KWT|rcsb pdb:2KWZ|rcsb pdb:3FQL|rcsb pdb:3FQM|rcsb pdb:3FQQ|rcsb pdb:3KN2|rcsb pdb:3KQH|rcsb pdb:3KQK|rcsb pdb:3KQL|rcsb pdb:3KQN|rcsb pdb:3KQU|rcsb pdb:3Q0Z|rcsb pdb:3QGD|rcsb pdb:3QGE|rcsb pdb:3QGF|rcsb pdb:3QGG|rcsb pdb:4NLD|rcsb pdb:4U01|go:"GO:0032991"(protein-containing complex)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0003723"(RNA binding)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003779"(actin binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5E4F|rcsb pdb:5PZK|rcsb pdb:5PZL|rcsb pdb:5PZM|rcsb pdb:5PZN|rcsb pdb:5PZO|rcsb pdb:5PZP|rcsb pdb:5TRH|rcsb pdb:5TRI|rcsb pdb:5TRJ|rcsb pdb:5TRK|rcsb pdb:5TWN|interpro:IPR042205|interpro:IPR042209|interpro:IPR043128|interpro:IPR027417|mint:Q9WMX2|interpro:IPR038170|interpro:IPR038568|interpro:IPR043502|interpro:IPR043504 ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:3GilwqS4csV8LvvR72ulHAcle3A333284 rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606 intact-crc:6EAC8F648749E980 false sufficient binding region:2-191|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMX2 uniprotkb:P22626 intact:EBI-710918 intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61 psi-mi:polg_hcvco(display_long) psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154835|imex:IM-17331-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0039690"(positive stranded viral RNA replication)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0075519"(microtubule-dependent intracellular transport of viral material)|go:"GO:0075520"(actin-dependent intracellular transport of virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1ZH1|rcsb pdb:2JY0|rcsb pdb:2KWT|rcsb pdb:2KWZ|rcsb pdb:3FQL|rcsb pdb:3FQM|rcsb pdb:3FQQ|rcsb pdb:3KN2|rcsb pdb:3KQH|rcsb pdb:3KQK|rcsb pdb:3KQL|rcsb pdb:3KQN|rcsb pdb:3KQU|rcsb pdb:3Q0Z|rcsb pdb:3QGD|rcsb pdb:3QGE|rcsb pdb:3QGF|rcsb pdb:3QGG|rcsb pdb:4NLD|rcsb pdb:4U01|go:"GO:0032991"(protein-containing complex)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0003723"(RNA binding)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003779"(actin binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5E4F|rcsb pdb:5PZK|rcsb pdb:5PZL|rcsb pdb:5PZM|rcsb pdb:5PZN|rcsb pdb:5PZO|rcsb pdb:5PZP|rcsb pdb:5TRH|rcsb pdb:5TRI|rcsb pdb:5TRJ|rcsb pdb:5TRK|rcsb pdb:5TWN|interpro:IPR042205|interpro:IPR042209|interpro:IPR043128|interpro:IPR027417|mint:Q9WMX2|interpro:IPR038170|interpro:IPR038568|interpro:IPR043502|interpro:IPR043504 go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:3GilwqS4csV8LvvR72ulHAcle3A333284 rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606 intact-crc:6EAC8F648749E980 false sufficient binding region:2-191|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMX2 uniprotkb:Q9BTM1 intact:EBI-710918 intact:EBI-4398590|uniprotkb:Q9NV63|ensembl:ENSP00000373730|ensembl:ENSP00000438553 psi-mi:polg_hcvco(display_long) psi-mi:h2aj_human(display_long)|uniprotkb:H2AJ(gene name)|psi-mi:H2AJ(display_short)|uniprotkb:H2AFJ(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154835|imex:IM-17331-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0039690"(positive stranded viral RNA replication)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0075519"(microtubule-dependent intracellular transport of viral material)|go:"GO:0075520"(actin-dependent intracellular transport of virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1ZH1|rcsb pdb:2JY0|rcsb pdb:2KWT|rcsb pdb:2KWZ|rcsb pdb:3FQL|rcsb pdb:3FQM|rcsb pdb:3FQQ|rcsb pdb:3KN2|rcsb pdb:3KQH|rcsb pdb:3KQK|rcsb pdb:3KQL|rcsb pdb:3KQN|rcsb pdb:3KQU|rcsb pdb:3Q0Z|rcsb pdb:3QGD|rcsb pdb:3QGE|rcsb pdb:3QGF|rcsb pdb:3QGG|rcsb pdb:4NLD|rcsb pdb:4U01|go:"GO:0032991"(protein-containing complex)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0003723"(RNA binding)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003779"(actin binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5E4F|rcsb pdb:5PZK|rcsb pdb:5PZL|rcsb pdb:5PZM|rcsb pdb:5PZN|rcsb pdb:5PZO|rcsb pdb:5PZP|rcsb pdb:5TRH|rcsb pdb:5TRI|rcsb pdb:5TRJ|rcsb pdb:5TRK|rcsb pdb:5TWN|interpro:IPR042205|interpro:IPR042209|interpro:IPR043128|interpro:IPR027417|mint:Q9WMX2|interpro:IPR038170|interpro:IPR038568|interpro:IPR043502|interpro:IPR043504 refseq:NP_808760.1|ensembl:ENSG00000246705(gene)|ensembl:ENST00000389078(transcript)|ensembl:ENST00000544848(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:4EDU|rcsb pdb:6K60|rcsb pdb:6KVD|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-8939236 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:3GilwqS4csV8LvvR72ulHAcle3A333284 rogid:g6br63FeM17yJRfQI3GnmoM0vbc9606 intact-crc:6EAC8F648749E980 false sufficient binding region:2-191|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMX2 uniprotkb:P04908 intact:EBI-710918 intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842 psi-mi:polg_hcvco(display_long) psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154835|imex:IM-17331-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0039690"(positive stranded viral RNA replication)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0075519"(microtubule-dependent intracellular transport of viral material)|go:"GO:0075520"(actin-dependent intracellular transport of virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1ZH1|rcsb pdb:2JY0|rcsb pdb:2KWT|rcsb pdb:2KWZ|rcsb pdb:3FQL|rcsb pdb:3FQM|rcsb pdb:3FQQ|rcsb pdb:3KN2|rcsb pdb:3KQH|rcsb pdb:3KQK|rcsb pdb:3KQL|rcsb pdb:3KQN|rcsb pdb:3KQU|rcsb pdb:3Q0Z|rcsb pdb:3QGD|rcsb pdb:3QGE|rcsb pdb:3QGF|rcsb pdb:3QGG|rcsb pdb:4NLD|rcsb pdb:4U01|go:"GO:0032991"(protein-containing complex)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0003723"(RNA binding)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003779"(actin binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5E4F|rcsb pdb:5PZK|rcsb pdb:5PZL|rcsb pdb:5PZM|rcsb pdb:5PZN|rcsb pdb:5PZO|rcsb pdb:5PZP|rcsb pdb:5TRH|rcsb pdb:5TRI|rcsb pdb:5TRJ|rcsb pdb:5TRK|rcsb pdb:5TWN|interpro:IPR042205|interpro:IPR042209|interpro:IPR043128|interpro:IPR027417|mint:Q9WMX2|interpro:IPR038170|interpro:IPR038568|interpro:IPR043502|interpro:IPR043504 refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:3GilwqS4csV8LvvR72ulHAcle3A333284 rogid:4Qno1mMYZB6FdNoojrzulWLVq849606 intact-crc:6EAC8F648749E980 false sufficient binding region:2-191|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMX2 uniprotkb:O00571 intact:EBI-710918 intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040 psi-mi:polg_hcvco(display_long) psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154835|imex:IM-17331-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0039690"(positive stranded viral RNA replication)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0075519"(microtubule-dependent intracellular transport of viral material)|go:"GO:0075520"(actin-dependent intracellular transport of virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1ZH1|rcsb pdb:2JY0|rcsb pdb:2KWT|rcsb pdb:2KWZ|rcsb pdb:3FQL|rcsb pdb:3FQM|rcsb pdb:3FQQ|rcsb pdb:3KN2|rcsb pdb:3KQH|rcsb pdb:3KQK|rcsb pdb:3KQL|rcsb pdb:3KQN|rcsb pdb:3KQU|rcsb pdb:3Q0Z|rcsb pdb:3QGD|rcsb pdb:3QGE|rcsb pdb:3QGF|rcsb pdb:3QGG|rcsb pdb:4NLD|rcsb pdb:4U01|go:"GO:0032991"(protein-containing complex)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0003723"(RNA binding)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003779"(actin binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5E4F|rcsb pdb:5PZK|rcsb pdb:5PZL|rcsb pdb:5PZM|rcsb pdb:5PZN|rcsb pdb:5PZO|rcsb pdb:5PZP|rcsb pdb:5TRH|rcsb pdb:5TRI|rcsb pdb:5TRJ|rcsb pdb:5TRK|rcsb pdb:5TWN|interpro:IPR042205|interpro:IPR042209|interpro:IPR043128|interpro:IPR027417|mint:Q9WMX2|interpro:IPR038170|interpro:IPR038568|interpro:IPR043502|interpro:IPR043504 refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:3GilwqS4csV8LvvR72ulHAcle3A333284 rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606 intact-crc:6EAC8F648749E980 false sufficient binding region:2-191|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMX2 intact:EBI-6147672 intact:EBI-710918 - psi-mi:polg_hcvco(display_long) psi-mi:p0c7m2_human(display_short)|psi-mi:EBI-6147672(display_long) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154835|imex:IM-17331-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0039690"(positive stranded viral RNA replication)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0075519"(microtubule-dependent intracellular transport of viral material)|go:"GO:0075520"(actin-dependent intracellular transport of virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1ZH1|rcsb pdb:2JY0|rcsb pdb:2KWT|rcsb pdb:2KWZ|rcsb pdb:3FQL|rcsb pdb:3FQM|rcsb pdb:3FQQ|rcsb pdb:3KN2|rcsb pdb:3KQH|rcsb pdb:3KQK|rcsb pdb:3KQL|rcsb pdb:3KQN|rcsb pdb:3KQU|rcsb pdb:3Q0Z|rcsb pdb:3QGD|rcsb pdb:3QGE|rcsb pdb:3QGF|rcsb pdb:3QGG|rcsb pdb:4NLD|rcsb pdb:4U01|go:"GO:0032991"(protein-containing complex)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0003723"(RNA binding)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003779"(actin binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5E4F|rcsb pdb:5PZK|rcsb pdb:5PZL|rcsb pdb:5PZM|rcsb pdb:5PZN|rcsb pdb:5PZO|rcsb pdb:5PZP|rcsb pdb:5TRH|rcsb pdb:5TRI|rcsb pdb:5TRJ|rcsb pdb:5TRK|rcsb pdb:5TWN|interpro:IPR042205|interpro:IPR042209|interpro:IPR043128|interpro:IPR027417|mint:Q9WMX2|interpro:IPR038170|interpro:IPR038568|interpro:IPR043502|interpro:IPR043504 uniprotkb:P0C7M2(uniprot-removed-ac) - - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:3GilwqS4csV8LvvR72ulHAcle3A333284 - intact-crc:6EAC8F648749E980 false sufficient binding region:2-191|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMX2 uniprotkb:P55209 intact:EBI-710918 intact:EBI-356392|ensembl:ENSP00000376947|ensembl:ENSP00000477538|uniprotkb:B3KV44|uniprotkb:B3KNT8 psi-mi:polg_hcvco(display_long) psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154835|imex:IM-17331-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0039690"(positive stranded viral RNA replication)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0075519"(microtubule-dependent intracellular transport of viral material)|go:"GO:0075520"(actin-dependent intracellular transport of virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1ZH1|rcsb pdb:2JY0|rcsb pdb:2KWT|rcsb pdb:2KWZ|rcsb pdb:3FQL|rcsb pdb:3FQM|rcsb pdb:3FQQ|rcsb pdb:3KN2|rcsb pdb:3KQH|rcsb pdb:3KQK|rcsb pdb:3KQL|rcsb pdb:3KQN|rcsb pdb:3KQU|rcsb pdb:3Q0Z|rcsb pdb:3QGD|rcsb pdb:3QGE|rcsb pdb:3QGF|rcsb pdb:3QGG|rcsb pdb:4NLD|rcsb pdb:4U01|go:"GO:0032991"(protein-containing complex)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0003723"(RNA binding)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003779"(actin binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5E4F|rcsb pdb:5PZK|rcsb pdb:5PZL|rcsb pdb:5PZM|rcsb pdb:5PZN|rcsb pdb:5PZO|rcsb pdb:5PZP|rcsb pdb:5TRH|rcsb pdb:5TRI|rcsb pdb:5TRJ|rcsb pdb:5TRK|rcsb pdb:5TWN|interpro:IPR042205|interpro:IPR042209|interpro:IPR043128|interpro:IPR027417|mint:Q9WMX2|interpro:IPR038170|interpro:IPR038568|interpro:IPR043502|interpro:IPR043504 ensembl:ENSG00000187109(gene)|ensembl:ENST00000393263(transcript)|ensembl:ENST00000618691(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|refseq:NP_004528.1|refseq:NP_631946.1|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:3GilwqS4csV8LvvR72ulHAcle3A333284 rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606 intact-crc:6EAC8F648749E980 false sufficient binding region:2-191|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMX2 uniprotkb:Q99878 intact:EBI-710918 intact:EBI-6147676|uniprotkb:Q5JXQ5|uniprotkb:A2RUU6|ensembl:ENSP00000328484 psi-mi:polg_hcvco(display_long) psi-mi:h2a1j_human(display_long)|uniprotkb:H2AC14(gene name)|psi-mi:H2AC14(display_short)|uniprotkb:H2AFE(gene name synonym)|uniprotkb:HIST1H2AJ(gene name synonym)|uniprotkb:Histone H2A/e(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154835|imex:IM-17331-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0039690"(positive stranded viral RNA replication)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0075519"(microtubule-dependent intracellular transport of viral material)|go:"GO:0075520"(actin-dependent intracellular transport of virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1ZH1|rcsb pdb:2JY0|rcsb pdb:2KWT|rcsb pdb:2KWZ|rcsb pdb:3FQL|rcsb pdb:3FQM|rcsb pdb:3FQQ|rcsb pdb:3KN2|rcsb pdb:3KQH|rcsb pdb:3KQK|rcsb pdb:3KQL|rcsb pdb:3KQN|rcsb pdb:3KQU|rcsb pdb:3Q0Z|rcsb pdb:3QGD|rcsb pdb:3QGE|rcsb pdb:3QGF|rcsb pdb:3QGG|rcsb pdb:4NLD|rcsb pdb:4U01|go:"GO:0032991"(protein-containing complex)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0003723"(RNA binding)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003779"(actin binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5E4F|rcsb pdb:5PZK|rcsb pdb:5PZL|rcsb pdb:5PZM|rcsb pdb:5PZN|rcsb pdb:5PZO|rcsb pdb:5PZP|rcsb pdb:5TRH|rcsb pdb:5TRI|rcsb pdb:5TRJ|rcsb pdb:5TRK|rcsb pdb:5TWN|interpro:IPR042205|interpro:IPR042209|interpro:IPR043128|interpro:IPR027417|mint:Q9WMX2|interpro:IPR038170|interpro:IPR038568|interpro:IPR043502|interpro:IPR043504 refseq:NP_066544.1|ensembl:ENSG00000276368(gene)|ensembl:ENST00000333151(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:3GilwqS4csV8LvvR72ulHAcle3A333284 rogid:tS29VG3PpglHaYbu0w5z7pGvYyI9606 intact-crc:6EAC8F648749E980 false sufficient binding region:2-191|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMX2 uniprotkb:P62269 intact:EBI-710918 intact:EBI-352451|ensembl:ENSP00000211372|ensembl:ENSP00000393241|ensembl:ENSP00000403175|ensembl:ENSP00000412583|ensembl:ENSP00000416110|uniprotkb:P25232|uniprotkb:Q6IPF8|uniprotkb:Q5SUJ3 psi-mi:polg_hcvco(display_long) psi-mi:rs18_human(display_long)|uniprotkb:RPS18(gene name)|psi-mi:RPS18(display_short)|uniprotkb:D6S218E(gene name synonym)|uniprotkb:Ke-3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS13(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154835|imex:IM-17331-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0039690"(positive stranded viral RNA replication)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0075519"(microtubule-dependent intracellular transport of viral material)|go:"GO:0075520"(actin-dependent intracellular transport of virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1ZH1|rcsb pdb:2JY0|rcsb pdb:2KWT|rcsb pdb:2KWZ|rcsb pdb:3FQL|rcsb pdb:3FQM|rcsb pdb:3FQQ|rcsb pdb:3KN2|rcsb pdb:3KQH|rcsb pdb:3KQK|rcsb pdb:3KQL|rcsb pdb:3KQN|rcsb pdb:3KQU|rcsb pdb:3Q0Z|rcsb pdb:3QGD|rcsb pdb:3QGE|rcsb pdb:3QGF|rcsb pdb:3QGG|rcsb pdb:4NLD|rcsb pdb:4U01|go:"GO:0032991"(protein-containing complex)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0003723"(RNA binding)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003779"(actin binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5E4F|rcsb pdb:5PZK|rcsb pdb:5PZL|rcsb pdb:5PZM|rcsb pdb:5PZN|rcsb pdb:5PZO|rcsb pdb:5PZP|rcsb pdb:5TRH|rcsb pdb:5TRI|rcsb pdb:5TRJ|rcsb pdb:5TRK|rcsb pdb:5TWN|interpro:IPR042205|interpro:IPR042209|interpro:IPR043128|interpro:IPR027417|mint:Q9WMX2|interpro:IPR038170|interpro:IPR038568|interpro:IPR043502|interpro:IPR043504 refseq:NP_072045.1|ensembl:ENSG00000096150(gene)|ensembl:ENSG00000223367(gene)|ensembl:ENSG00000226225(gene)|ensembl:ENSG00000231500(gene)|ensembl:ENSG00000235650(gene)|ensembl:ENST00000211372(transcript)|ensembl:ENST00000434122(transcript)|ensembl:ENST00000439602(transcript)|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENST00000454021(transcript)|ensembl:ENST00000457341(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001892(Ribosomal protein S13)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR018269|interpro:IPR027437|mint:P62269|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|dip:DIP-32892N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:3GilwqS4csV8LvvR72ulHAcle3A333284 rogid:yOHgKM/BuvgGdqp1OEVPeuiABg89606 intact-crc:6EAC8F648749E980 false sufficient binding region:2-191|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMX2 uniprotkb:P31943 intact:EBI-710918 intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168|ensembl:ENSP00000377082|ensembl:ENSP00000397797|ensembl:ENSP00000492076|ensembl:ENSP00000495786 psi-mi:polg_hcvco(display_long) psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154835|imex:IM-17331-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0039690"(positive stranded viral RNA replication)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0075519"(microtubule-dependent intracellular transport of viral material)|go:"GO:0075520"(actin-dependent intracellular transport of virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1ZH1|rcsb pdb:2JY0|rcsb pdb:2KWT|rcsb pdb:2KWZ|rcsb pdb:3FQL|rcsb pdb:3FQM|rcsb pdb:3FQQ|rcsb pdb:3KN2|rcsb pdb:3KQH|rcsb pdb:3KQK|rcsb pdb:3KQL|rcsb pdb:3KQN|rcsb pdb:3KQU|rcsb pdb:3Q0Z|rcsb pdb:3QGD|rcsb pdb:3QGE|rcsb pdb:3QGF|rcsb pdb:3QGG|rcsb pdb:4NLD|rcsb pdb:4U01|go:"GO:0032991"(protein-containing complex)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0003723"(RNA binding)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003779"(actin binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5E4F|rcsb pdb:5PZK|rcsb pdb:5PZL|rcsb pdb:5PZM|rcsb pdb:5PZN|rcsb pdb:5PZO|rcsb pdb:5PZP|rcsb pdb:5TRH|rcsb pdb:5TRI|rcsb pdb:5TRJ|rcsb pdb:5TRK|rcsb pdb:5TWN|interpro:IPR042205|interpro:IPR042209|interpro:IPR043128|interpro:IPR027417|mint:Q9WMX2|interpro:IPR038170|interpro:IPR038568|interpro:IPR043502|interpro:IPR043504 refseq:NP_005511.1|refseq:NP_001244222.1|ensembl:ENSG00000169045(gene)|ensembl:ENSG00000284254(gene)|ensembl:ENST00000356731(transcript)|ensembl:ENST00000393432(transcript)|ensembl:ENST00000442819(transcript)|ensembl:ENST00000638505(transcript)|ensembl:ENST00000643310(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:3GilwqS4csV8LvvR72ulHAcle3A333284 rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606 intact-crc:6EAC8F648749E980 false sufficient binding region:2-191|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMX2 uniprotkb:Q16777 intact:EBI-710918 intact:EBI-5325566|ensembl:ENSP00000332194|uniprotkb:Q6DRA7|uniprotkb:Q8IUE5 psi-mi:polg_hcvco(display_long) psi-mi:h2a2c_human(display_long)|uniprotkb:H2AC20(gene name)|psi-mi:H2AC20(display_short)|uniprotkb:H2A-clustered histone 20(gene name synonym)|uniprotkb:H2AFQ(gene name synonym)|uniprotkb:HIST2H2AC(gene name synonym)|uniprotkb:Histone H2A-GL101(gene name synonym)|uniprotkb:Histone H2A/q(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154835|imex:IM-17331-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0039690"(positive stranded viral RNA replication)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0075519"(microtubule-dependent intracellular transport of viral material)|go:"GO:0075520"(actin-dependent intracellular transport of virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1ZH1|rcsb pdb:2JY0|rcsb pdb:2KWT|rcsb pdb:2KWZ|rcsb pdb:3FQL|rcsb pdb:3FQM|rcsb pdb:3FQQ|rcsb pdb:3KN2|rcsb pdb:3KQH|rcsb pdb:3KQK|rcsb pdb:3KQL|rcsb pdb:3KQN|rcsb pdb:3KQU|rcsb pdb:3Q0Z|rcsb pdb:3QGD|rcsb pdb:3QGE|rcsb pdb:3QGF|rcsb pdb:3QGG|rcsb pdb:4NLD|rcsb pdb:4U01|go:"GO:0032991"(protein-containing complex)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0003723"(RNA binding)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003779"(actin binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5E4F|rcsb pdb:5PZK|rcsb pdb:5PZL|rcsb pdb:5PZM|rcsb pdb:5PZN|rcsb pdb:5PZO|rcsb pdb:5PZP|rcsb pdb:5TRH|rcsb pdb:5TRI|rcsb pdb:5TRJ|rcsb pdb:5TRK|rcsb pdb:5TWN|interpro:IPR042205|interpro:IPR042209|interpro:IPR043128|interpro:IPR027417|mint:Q9WMX2|interpro:IPR038170|interpro:IPR038568|interpro:IPR043502|interpro:IPR043504 reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-5689603|ensembl:ENSG00000184260(gene)|ensembl:ENST00000331380(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q16777|rcsb pdb:6Y5E|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|refseq:NP_003508.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:3GilwqS4csV8LvvR72ulHAcle3A333284 rogid:Wejrpp9wK3GvA4ahJDVyEH+cwlQ9606 intact-crc:6EAC8F648749E980 false sufficient binding region:2-191|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMX2 uniprotkb:P62805 intact:EBI-710918 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:polg_hcvco(display_long) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154835|imex:IM-17331-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0039690"(positive stranded viral RNA replication)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0075519"(microtubule-dependent intracellular transport of viral material)|go:"GO:0075520"(actin-dependent intracellular transport of virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1ZH1|rcsb pdb:2JY0|rcsb pdb:2KWT|rcsb pdb:2KWZ|rcsb pdb:3FQL|rcsb pdb:3FQM|rcsb pdb:3FQQ|rcsb pdb:3KN2|rcsb pdb:3KQH|rcsb pdb:3KQK|rcsb pdb:3KQL|rcsb pdb:3KQN|rcsb pdb:3KQU|rcsb pdb:3Q0Z|rcsb pdb:3QGD|rcsb pdb:3QGE|rcsb pdb:3QGF|rcsb pdb:3QGG|rcsb pdb:4NLD|rcsb pdb:4U01|go:"GO:0032991"(protein-containing complex)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0003723"(RNA binding)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003779"(actin binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5E4F|rcsb pdb:5PZK|rcsb pdb:5PZL|rcsb pdb:5PZM|rcsb pdb:5PZN|rcsb pdb:5PZO|rcsb pdb:5PZP|rcsb pdb:5TRH|rcsb pdb:5TRI|rcsb pdb:5TRJ|rcsb pdb:5TRK|rcsb pdb:5TWN|interpro:IPR042205|interpro:IPR042209|interpro:IPR043128|interpro:IPR027417|mint:Q9WMX2|interpro:IPR038170|interpro:IPR038568|interpro:IPR043502|interpro:IPR043504 ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:3GilwqS4csV8LvvR72ulHAcle3A333284 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:6EAC8F648749E980 false sufficient binding region:2-191|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMX2 uniprotkb:Q93077 intact:EBI-710918 intact:EBI-725259|uniprotkb:O00775|uniprotkb:O00776|uniprotkb:O00777|uniprotkb:O00778|uniprotkb:Q540R1|uniprotkb:B2R4F7|ensembl:ENSP00000321389|ensembl:ENSP00000367022|ensembl:ENSP00000473534 psi-mi:polg_hcvco(display_long) psi-mi:h2a1c_human(display_long)|uniprotkb:H2AC6(gene name)|psi-mi:H2AC6(display_short)|uniprotkb:H2A-clustered histone 6(gene name synonym)|uniprotkb:H2AFL(gene name synonym)|uniprotkb:HIST1H2AC(gene name synonym)|uniprotkb:Histone H2A/l(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154835|imex:IM-17331-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0039690"(positive stranded viral RNA replication)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0075519"(microtubule-dependent intracellular transport of viral material)|go:"GO:0075520"(actin-dependent intracellular transport of virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1ZH1|rcsb pdb:2JY0|rcsb pdb:2KWT|rcsb pdb:2KWZ|rcsb pdb:3FQL|rcsb pdb:3FQM|rcsb pdb:3FQQ|rcsb pdb:3KN2|rcsb pdb:3KQH|rcsb pdb:3KQK|rcsb pdb:3KQL|rcsb pdb:3KQN|rcsb pdb:3KQU|rcsb pdb:3Q0Z|rcsb pdb:3QGD|rcsb pdb:3QGE|rcsb pdb:3QGF|rcsb pdb:3QGG|rcsb pdb:4NLD|rcsb pdb:4U01|go:"GO:0032991"(protein-containing complex)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0003723"(RNA binding)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003779"(actin binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5E4F|rcsb pdb:5PZK|rcsb pdb:5PZL|rcsb pdb:5PZM|rcsb pdb:5PZN|rcsb pdb:5PZO|rcsb pdb:5PZP|rcsb pdb:5TRH|rcsb pdb:5TRI|rcsb pdb:5TRJ|rcsb pdb:5TRK|rcsb pdb:5TWN|interpro:IPR042205|interpro:IPR042209|interpro:IPR043128|interpro:IPR027417|mint:Q9WMX2|interpro:IPR038170|interpro:IPR038568|interpro:IPR043502|interpro:IPR043504 refseq:NP_003503.1|ensembl:ENSG00000180573(gene)|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENST00000314088(transcript)|ensembl:ENST00000377791(transcript)|ensembl:ENST00000602637(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|rcsb pdb:6C0W|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:7A08|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|interpro:IPR032458 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:3GilwqS4csV8LvvR72ulHAcle3A333284 rogid:m00IdooZksbNGKHSsaVvGFVpcko9606 intact-crc:6EAC8F648749E980 false sufficient binding region:2-191|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMX2 uniprotkb:Q6FI13 intact:EBI-710918 intact:EBI-353620|uniprotkb:P20670|uniprotkb:B2R5F0|ensembl:ENSP00000358155|ensembl:ENSP00000475814 psi-mi:polg_hcvco(display_long) psi-mi:h2a2a_human(display_long)|uniprotkb:H2AC18(gene name)|psi-mi:H2AC18(display_short)|uniprotkb:H2AC19(gene name)|psi-mi:H2AC19(display_short)|uniprotkb:H2A-clustered histone 18(gene name synonym)|uniprotkb:H2A-clustered histone 19(gene name synonym)|uniprotkb:H2AFO(gene name synonym)|uniprotkb:HIST2H2AA(gene name synonym)|uniprotkb:HIST2H2AA3(gene name synonym)|uniprotkb:HIST2H2AA4(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/o(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154835|imex:IM-17331-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0039690"(positive stranded viral RNA replication)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0075519"(microtubule-dependent intracellular transport of viral material)|go:"GO:0075520"(actin-dependent intracellular transport of virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1ZH1|rcsb pdb:2JY0|rcsb pdb:2KWT|rcsb pdb:2KWZ|rcsb pdb:3FQL|rcsb pdb:3FQM|rcsb pdb:3FQQ|rcsb pdb:3KN2|rcsb pdb:3KQH|rcsb pdb:3KQK|rcsb pdb:3KQL|rcsb pdb:3KQN|rcsb pdb:3KQU|rcsb pdb:3Q0Z|rcsb pdb:3QGD|rcsb pdb:3QGE|rcsb pdb:3QGF|rcsb pdb:3QGG|rcsb pdb:4NLD|rcsb pdb:4U01|go:"GO:0032991"(protein-containing complex)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0003723"(RNA binding)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003779"(actin binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5E4F|rcsb pdb:5PZK|rcsb pdb:5PZL|rcsb pdb:5PZM|rcsb pdb:5PZN|rcsb pdb:5PZO|rcsb pdb:5PZP|rcsb pdb:5TRH|rcsb pdb:5TRI|rcsb pdb:5TRJ|rcsb pdb:5TRK|rcsb pdb:5TWN|interpro:IPR042205|interpro:IPR042209|interpro:IPR043128|interpro:IPR027417|mint:Q9WMX2|interpro:IPR038170|interpro:IPR038568|interpro:IPR043502|interpro:IPR043504 refseq:NP_001035807.1|refseq:NP_003507.1|ensembl:ENSG00000203812(gene)|ensembl:ENSG00000272196(gene)|ensembl:ENST00000369159(transcript)|ensembl:ENST00000607355(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6Y5D|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|dip:DIP-33167N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:3GilwqS4csV8LvvR72ulHAcle3A333284 rogid:PMuIm2XMN5q4wk+wYJ94mmnCe4w9606 intact-crc:6EAC8F648749E980 false sufficient binding region:2-191|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMX2 uniprotkb:Q99733 intact:EBI-710918 intact:EBI-2255116|uniprotkb:B2R6J4|uniprotkb:F5HFY4|ensembl:ENSP00000369915|ensembl:ENSP00000483728 psi-mi:polg_hcvco(display_long) psi-mi:np1l4_human(display_long)|uniprotkb:NAP1L4(gene name)|psi-mi:NAP1L4(display_short)|uniprotkb:NAP2(gene name synonym)|uniprotkb:Nucleosome assembly protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154835|imex:IM-17331-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0039690"(positive stranded viral RNA replication)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0075519"(microtubule-dependent intracellular transport of viral material)|go:"GO:0075520"(actin-dependent intracellular transport of virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1ZH1|rcsb pdb:2JY0|rcsb pdb:2KWT|rcsb pdb:2KWZ|rcsb pdb:3FQL|rcsb pdb:3FQM|rcsb pdb:3FQQ|rcsb pdb:3KN2|rcsb pdb:3KQH|rcsb pdb:3KQK|rcsb pdb:3KQL|rcsb pdb:3KQN|rcsb pdb:3KQU|rcsb pdb:3Q0Z|rcsb pdb:3QGD|rcsb pdb:3QGE|rcsb pdb:3QGF|rcsb pdb:3QGG|rcsb pdb:4NLD|rcsb pdb:4U01|go:"GO:0032991"(protein-containing complex)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0003723"(RNA binding)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003779"(actin binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5E4F|rcsb pdb:5PZK|rcsb pdb:5PZL|rcsb pdb:5PZM|rcsb pdb:5PZN|rcsb pdb:5PZO|rcsb pdb:5PZP|rcsb pdb:5TRH|rcsb pdb:5TRI|rcsb pdb:5TRJ|rcsb pdb:5TRK|rcsb pdb:5TWN|interpro:IPR042205|interpro:IPR042209|interpro:IPR043128|interpro:IPR027417|mint:Q9WMX2|interpro:IPR038170|interpro:IPR038568|interpro:IPR043502|interpro:IPR043504 refseq:NP_005960.1|ensembl:ENSG00000205531(gene)|ensembl:ENSG00000273562(gene)|ensembl:ENST00000380542(transcript)|ensembl:ENST00000619695(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q99733 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:3GilwqS4csV8LvvR72ulHAcle3A333284 rogid:tES8IJDlW4JONR/pdC8dq49I/7Y9606 intact-crc:6EAC8F648749E980 false sufficient binding region:2-191|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMX2 uniprotkb:Q96KK5 intact:EBI-710918 intact:EBI-6147668|ensembl:ENSP00000366679 psi-mi:polg_hcvco(display_long) psi-mi:h2a1h_human(display_long)|uniprotkb:H2AC12(gene name)|psi-mi:H2AC12(display_short)|uniprotkb:H2A-clustered histone 12(gene name synonym)|uniprotkb:HIST1H2AH(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:Histone H2A/s(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154835|imex:IM-17331-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0039690"(positive stranded viral RNA replication)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0075519"(microtubule-dependent intracellular transport of viral material)|go:"GO:0075520"(actin-dependent intracellular transport of virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1ZH1|rcsb pdb:2JY0|rcsb pdb:2KWT|rcsb pdb:2KWZ|rcsb pdb:3FQL|rcsb pdb:3FQM|rcsb pdb:3FQQ|rcsb pdb:3KN2|rcsb pdb:3KQH|rcsb pdb:3KQK|rcsb pdb:3KQL|rcsb pdb:3KQN|rcsb pdb:3KQU|rcsb pdb:3Q0Z|rcsb pdb:3QGD|rcsb pdb:3QGE|rcsb pdb:3QGF|rcsb pdb:3QGG|rcsb pdb:4NLD|rcsb pdb:4U01|go:"GO:0032991"(protein-containing complex)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0003723"(RNA binding)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003779"(actin binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5E4F|rcsb pdb:5PZK|rcsb pdb:5PZL|rcsb pdb:5PZM|rcsb pdb:5PZN|rcsb pdb:5PZO|rcsb pdb:5PZP|rcsb pdb:5TRH|rcsb pdb:5TRI|rcsb pdb:5TRJ|rcsb pdb:5TRK|rcsb pdb:5TWN|interpro:IPR042205|interpro:IPR042209|interpro:IPR043128|interpro:IPR027417|mint:Q9WMX2|interpro:IPR038170|interpro:IPR038568|interpro:IPR043502|interpro:IPR043504 refseq:NP_542163.1|dip:DIP-61699N|ensembl:ENSG00000274997(gene)|ensembl:ENST00000377459(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:3GilwqS4csV8LvvR72ulHAcle3A333284 rogid:Oa322n+evy8Cu0E9cWTEdYwQPKM9606 intact-crc:6EAC8F648749E980 false sufficient binding region:2-191|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMX2 uniprotkb:Q32P51 intact:EBI-710918 intact:EBI-2556580|uniprotkb:Q5TBS2|ensembl:ENSP00000350090 psi-mi:polg_hcvco(display_long) psi-mi:ra1l2_human(display_long)|uniprotkb:HNRNPA1L(gene name synonym)|uniprotkb:HNRNPA1L2(gene name)|psi-mi:HNRNPA1L2(display_short)|uniprotkb:hnRNP core protein A1-like 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154835|imex:IM-17331-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0039690"(positive stranded viral RNA replication)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0075519"(microtubule-dependent intracellular transport of viral material)|go:"GO:0075520"(actin-dependent intracellular transport of virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1ZH1|rcsb pdb:2JY0|rcsb pdb:2KWT|rcsb pdb:2KWZ|rcsb pdb:3FQL|rcsb pdb:3FQM|rcsb pdb:3FQQ|rcsb pdb:3KN2|rcsb pdb:3KQH|rcsb pdb:3KQK|rcsb pdb:3KQL|rcsb pdb:3KQN|rcsb pdb:3KQU|rcsb pdb:3Q0Z|rcsb pdb:3QGD|rcsb pdb:3QGE|rcsb pdb:3QGF|rcsb pdb:3QGG|rcsb pdb:4NLD|rcsb pdb:4U01|go:"GO:0032991"(protein-containing complex)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0003723"(RNA binding)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003779"(actin binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5E4F|rcsb pdb:5PZK|rcsb pdb:5PZL|rcsb pdb:5PZM|rcsb pdb:5PZN|rcsb pdb:5PZO|rcsb pdb:5PZP|rcsb pdb:5TRH|rcsb pdb:5TRI|rcsb pdb:5TRJ|rcsb pdb:5TRK|rcsb pdb:5TWN|interpro:IPR042205|interpro:IPR042209|interpro:IPR043128|interpro:IPR027417|mint:Q9WMX2|interpro:IPR038170|interpro:IPR038568|interpro:IPR043502|interpro:IPR043504 refseq:NP_001011724.1|refseq:NP_001011725.1|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0051028"(mRNA transport)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR035979|mint:Q32P51|go:"GO:0005681"(spliceosomal complex)|ensembl:ENSG00000139675(gene)|ensembl:ENST00000357495(transcript)|go:"GO:0003723"(RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:3GilwqS4csV8LvvR72ulHAcle3A333284 rogid:Xx00SLimJrf+0e9CrvzUV9PJPcI9606 intact-crc:6EAC8F648749E980 false sufficient binding region:2-191|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMX2 uniprotkb:P09651 intact:EBI-710918 intact:EBI-352662|uniprotkb:Q3MIB7|uniprotkb:Q6PJZ7|ensembl:ENSP00000341826|ensembl:ENSP00000503610|uniprotkb:A8K4Z8|intact:EBI-2556572 psi-mi:polg_hcvco(display_long) psi-mi:roa1_human(display_long)|uniprotkb:HNRNPA1(gene name)|psi-mi:HNRNPA1(display_short)|uniprotkb:HNRPA1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:Single-strand RNA-binding protein(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:333284(hcvco)|taxid:333284("Hepatitis C virus genotype 1b (isolate Con1) (HCV)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154835|imex:IM-17331-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0039690"(positive stranded viral RNA replication)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0075519"(microtubule-dependent intracellular transport of viral material)|go:"GO:0075520"(actin-dependent intracellular transport of virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1ZH1|rcsb pdb:2JY0|rcsb pdb:2KWT|rcsb pdb:2KWZ|rcsb pdb:3FQL|rcsb pdb:3FQM|rcsb pdb:3FQQ|rcsb pdb:3KN2|rcsb pdb:3KQH|rcsb pdb:3KQK|rcsb pdb:3KQL|rcsb pdb:3KQN|rcsb pdb:3KQU|rcsb pdb:3Q0Z|rcsb pdb:3QGD|rcsb pdb:3QGE|rcsb pdb:3QGF|rcsb pdb:3QGG|rcsb pdb:4NLD|rcsb pdb:4U01|go:"GO:0032991"(protein-containing complex)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0003723"(RNA binding)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003779"(actin binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030430"(host cell cytoplasm)|rcsb pdb:5E4F|rcsb pdb:5PZK|rcsb pdb:5PZL|rcsb pdb:5PZM|rcsb pdb:5PZN|rcsb pdb:5PZO|rcsb pdb:5PZP|rcsb pdb:5TRH|rcsb pdb:5TRI|rcsb pdb:5TRJ|rcsb pdb:5TRK|rcsb pdb:5TWN|interpro:IPR042205|interpro:IPR042209|interpro:IPR043128|interpro:IPR027417|mint:Q9WMX2|interpro:IPR038170|interpro:IPR038568|interpro:IPR043502|interpro:IPR043504 refseq:NP_002127.1|refseq:NP_112420.1|ensembl:ENSG00000135486(gene)|ensembl:ENST00000340913(transcript)|ensembl:ENST00000677210(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|rcsb pdb:2LYV|rcsb pdb:2UP1|rcsb pdb:4YOE|rcsb pdb:5MPG|rcsb pdb:5MPL|rcsb pdb:5ZGD|rcsb pdb:5ZGL|rcsb pdb:6BXX|rcsb pdb:6DCL|rcsb pdb:6J60|rcsb pdb:7BX7|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035198"(miRNA binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051170"(import into nucleus)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR034845|interpro:IPR035979|mint:P09651|rcsb pdb:1HA1|rcsb pdb:1L3K|rcsb pdb:1PGZ|rcsb pdb:1PO6|rcsb pdb:1U1K|rcsb pdb:1U1L|rcsb pdb:1U1M|rcsb pdb:1U1N|rcsb pdb:1U1O|rcsb pdb:1U1P|rcsb pdb:1U1Q|rcsb pdb:1U1R|rcsb pdb:1UP1|rcsb pdb:2H4M|refseq:XP_005268883.1|dip:DIP-29338N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:3GilwqS4csV8LvvR72ulHAcle3A333284 rogid:ECXjsLRVtNc/aOw90tEFxowHc6c9606 intact-crc:6EAC8F648749E980 false sufficient binding region:2-191|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03495 uniprotkb:Q02539 intact:EBI-2548993|uniprotkb:Q1K9D5 intact:EBI-932603|uniprotkb:Q3MJ34|ensembl:ENSP00000244573 psi-mi:ns1_i72a2(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h11_human(display_long)|uniprotkb:H1-1(gene name)|psi-mi:H1-1(display_short)|uniprotkb:H1F1(gene name synonym)|uniprotkb:HIST1H1A(gene name synonym)|uniprotkb:Histone H1a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:381517(i72a2)|taxid:381517("Influenza A virus (strain A/Udorn/307/1972 H3N2)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154909|imex:IM-17331-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0052038"(modulation by symbiont of host intracellular transport)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|interpro:IPR000256("Influenza non-structural protein (NS1)")|go:"GO:0046775"(suppression by virus of host cytokine production)|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:1AIL|rcsb pdb:1NS1|rcsb pdb:2KKZ|rcsb pdb:2RHK|rcsb pdb:3EE8|rcsb pdb:3EE9|rcsb pdb:3KWG|rcsb pdb:3KWI|rcsb pdb:4NW2|rcsb pdb:4O45|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|dip:DIP-46282N refseq:NP_005316.1|ensembl:ENSG00000124610(gene)|ensembl:ENST00000244573(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q02539|reactome:R-HSA-140342|reactome:R-HSA-2559584 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:VyosjYP0De3Y+BRJoOxL/BcF3NU381517 rogid:4u8P8jFM3onWx43+SxL320urjhk9606 intact-crc:22F020AA8AABB4AE|rigid:Or6MuwfnAOmS+LkHUJ6oA+7CIQk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03495 uniprotkb:Q93077 intact:EBI-2548993|uniprotkb:Q1K9D5 intact:EBI-725259|uniprotkb:O00775|uniprotkb:O00776|uniprotkb:O00777|uniprotkb:O00778|uniprotkb:Q540R1|uniprotkb:B2R4F7|ensembl:ENSP00000321389|ensembl:ENSP00000367022|ensembl:ENSP00000473534 psi-mi:ns1_i72a2(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a1c_human(display_long)|uniprotkb:H2AC6(gene name)|psi-mi:H2AC6(display_short)|uniprotkb:H2A-clustered histone 6(gene name synonym)|uniprotkb:H2AFL(gene name synonym)|uniprotkb:HIST1H2AC(gene name synonym)|uniprotkb:Histone H2A/l(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:381517(i72a2)|taxid:381517("Influenza A virus (strain A/Udorn/307/1972 H3N2)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154909|imex:IM-17331-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0052038"(modulation by symbiont of host intracellular transport)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|interpro:IPR000256("Influenza non-structural protein (NS1)")|go:"GO:0046775"(suppression by virus of host cytokine production)|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:1AIL|rcsb pdb:1NS1|rcsb pdb:2KKZ|rcsb pdb:2RHK|rcsb pdb:3EE8|rcsb pdb:3EE9|rcsb pdb:3KWG|rcsb pdb:3KWI|rcsb pdb:4NW2|rcsb pdb:4O45|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|dip:DIP-46282N refseq:NP_003503.1|ensembl:ENSG00000180573(gene)|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENST00000314088(transcript)|ensembl:ENST00000377791(transcript)|ensembl:ENST00000602637(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|rcsb pdb:6C0W|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:7A08|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|interpro:IPR032458 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:VyosjYP0De3Y+BRJoOxL/BcF3NU381517 rogid:m00IdooZksbNGKHSsaVvGFVpcko9606 intact-crc:22F020AA8AABB4AE|rigid:Or6MuwfnAOmS+LkHUJ6oA+7CIQk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03495 uniprotkb:Q5QNW6 intact:EBI-2548993|uniprotkb:Q1K9D5 intact:EBI-6147754|uniprotkb:B4DLA9|uniprotkb:A8K0U9|ensembl:ENSP00000358164 psi-mi:ns1_i72a2(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2b2f_human(display_long)|uniprotkb:H2BC18(gene name)|psi-mi:H2BC18(display_short)|uniprotkb:H2B-clustered histone 18(gene name synonym)|uniprotkb:HIST2H2BF(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:381517(i72a2)|taxid:381517("Influenza A virus (strain A/Udorn/307/1972 H3N2)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154909|imex:IM-17331-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0052038"(modulation by symbiont of host intracellular transport)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|interpro:IPR000256("Influenza non-structural protein (NS1)")|go:"GO:0046775"(suppression by virus of host cytokine production)|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:1AIL|rcsb pdb:1NS1|rcsb pdb:2KKZ|rcsb pdb:2RHK|rcsb pdb:3EE8|rcsb pdb:3EE9|rcsb pdb:3KWG|rcsb pdb:3KWI|rcsb pdb:4NW2|rcsb pdb:4O45|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|dip:DIP-46282N refseq:NP_001019770.1|refseq:NP_001154806.1|ensembl:ENSG00000203814(gene)|ensembl:ENST00000369167(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q5QNW6|rcsb pdb:6MUO|rcsb pdb:6MUP|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-5689880|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:VyosjYP0De3Y+BRJoOxL/BcF3NU381517 rogid:Pr400UVIaD7O446lc9vZeStUKn09606 intact-crc:22F020AA8AABB4AE|rigid:Or6MuwfnAOmS+LkHUJ6oA+7CIQk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03495 uniprotkb:P62805 intact:EBI-2548993|uniprotkb:Q1K9D5 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:ns1_i72a2(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:381517(i72a2)|taxid:381517("Influenza A virus (strain A/Udorn/307/1972 H3N2)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154909|imex:IM-17331-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0052038"(modulation by symbiont of host intracellular transport)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|interpro:IPR000256("Influenza non-structural protein (NS1)")|go:"GO:0046775"(suppression by virus of host cytokine production)|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:1AIL|rcsb pdb:1NS1|rcsb pdb:2KKZ|rcsb pdb:2RHK|rcsb pdb:3EE8|rcsb pdb:3EE9|rcsb pdb:3KWG|rcsb pdb:3KWI|rcsb pdb:4NW2|rcsb pdb:4O45|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|dip:DIP-46282N ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:VyosjYP0De3Y+BRJoOxL/BcF3NU381517 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:22F020AA8AABB4AE|rigid:Or6MuwfnAOmS+LkHUJ6oA+7CIQk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03495 uniprotkb:P04908 intact:EBI-2548993|uniprotkb:Q1K9D5 intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842 psi-mi:ns1_i72a2(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:381517(i72a2)|taxid:381517("Influenza A virus (strain A/Udorn/307/1972 H3N2)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154909|imex:IM-17331-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0052038"(modulation by symbiont of host intracellular transport)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|interpro:IPR000256("Influenza non-structural protein (NS1)")|go:"GO:0046775"(suppression by virus of host cytokine production)|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:1AIL|rcsb pdb:1NS1|rcsb pdb:2KKZ|rcsb pdb:2RHK|rcsb pdb:3EE8|rcsb pdb:3EE9|rcsb pdb:3KWG|rcsb pdb:3KWI|rcsb pdb:4NW2|rcsb pdb:4O45|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|dip:DIP-46282N refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:VyosjYP0De3Y+BRJoOxL/BcF3NU381517 rogid:4Qno1mMYZB6FdNoojrzulWLVq849606 intact-crc:22F020AA8AABB4AE|rigid:Or6MuwfnAOmS+LkHUJ6oA+7CIQk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03495 uniprotkb:Q16777 intact:EBI-2548993|uniprotkb:Q1K9D5 intact:EBI-5325566|ensembl:ENSP00000332194|uniprotkb:Q6DRA7|uniprotkb:Q8IUE5 psi-mi:ns1_i72a2(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a2c_human(display_long)|uniprotkb:H2AC20(gene name)|psi-mi:H2AC20(display_short)|uniprotkb:H2A-clustered histone 20(gene name synonym)|uniprotkb:H2AFQ(gene name synonym)|uniprotkb:HIST2H2AC(gene name synonym)|uniprotkb:Histone H2A-GL101(gene name synonym)|uniprotkb:Histone H2A/q(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:381517(i72a2)|taxid:381517("Influenza A virus (strain A/Udorn/307/1972 H3N2)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154909|imex:IM-17331-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0052038"(modulation by symbiont of host intracellular transport)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|interpro:IPR000256("Influenza non-structural protein (NS1)")|go:"GO:0046775"(suppression by virus of host cytokine production)|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:1AIL|rcsb pdb:1NS1|rcsb pdb:2KKZ|rcsb pdb:2RHK|rcsb pdb:3EE8|rcsb pdb:3EE9|rcsb pdb:3KWG|rcsb pdb:3KWI|rcsb pdb:4NW2|rcsb pdb:4O45|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|dip:DIP-46282N reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-5689603|ensembl:ENSG00000184260(gene)|ensembl:ENST00000331380(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q16777|rcsb pdb:6Y5E|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|refseq:NP_003508.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:VyosjYP0De3Y+BRJoOxL/BcF3NU381517 rogid:Wejrpp9wK3GvA4ahJDVyEH+cwlQ9606 intact-crc:22F020AA8AABB4AE|rigid:Or6MuwfnAOmS+LkHUJ6oA+7CIQk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03495 uniprotkb:Q99880 intact:EBI-2548993|uniprotkb:Q1K9D5 intact:EBI-1237119|uniprotkb:Q52LW9|uniprotkb:B2R5A3|ensembl:ENSP00000366618 psi-mi:ns1_i72a2(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2b1l_human(display_long)|uniprotkb:H2BC13(gene name)|psi-mi:H2BC13(display_short)|uniprotkb:H2BFC(gene name synonym)|uniprotkb:HIST1H2BL(gene name synonym)|uniprotkb:Histone H2B.c(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:381517(i72a2)|taxid:381517("Influenza A virus (strain A/Udorn/307/1972 H3N2)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154909|imex:IM-17331-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0052038"(modulation by symbiont of host intracellular transport)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|interpro:IPR000256("Influenza non-structural protein (NS1)")|go:"GO:0046775"(suppression by virus of host cytokine production)|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:1AIL|rcsb pdb:1NS1|rcsb pdb:2KKZ|rcsb pdb:2RHK|rcsb pdb:3EE8|rcsb pdb:3EE9|rcsb pdb:3KWG|rcsb pdb:3KWI|rcsb pdb:4NW2|rcsb pdb:4O45|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|dip:DIP-46282N refseq:NP_003510.1|dip:DIP-38154N|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|ensembl:ENSG00000185130(gene)|ensembl:ENST00000377401(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|interpro:IPR009072(Histone-fold)|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5250924|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:VyosjYP0De3Y+BRJoOxL/BcF3NU381517 rogid:vVD3xoHavMKCopzEez7zarZBKFc9606 intact-crc:22F020AA8AABB4AE|rigid:Or6MuwfnAOmS+LkHUJ6oA+7CIQk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03495 uniprotkb:Q99878 intact:EBI-2548993|uniprotkb:Q1K9D5 intact:EBI-6147676|uniprotkb:Q5JXQ5|uniprotkb:A2RUU6|ensembl:ENSP00000328484 psi-mi:ns1_i72a2(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a1j_human(display_long)|uniprotkb:H2AC14(gene name)|psi-mi:H2AC14(display_short)|uniprotkb:H2AFE(gene name synonym)|uniprotkb:HIST1H2AJ(gene name synonym)|uniprotkb:Histone H2A/e(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:381517(i72a2)|taxid:381517("Influenza A virus (strain A/Udorn/307/1972 H3N2)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154909|imex:IM-17331-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0052038"(modulation by symbiont of host intracellular transport)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|interpro:IPR000256("Influenza non-structural protein (NS1)")|go:"GO:0046775"(suppression by virus of host cytokine production)|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:1AIL|rcsb pdb:1NS1|rcsb pdb:2KKZ|rcsb pdb:2RHK|rcsb pdb:3EE8|rcsb pdb:3EE9|rcsb pdb:3KWG|rcsb pdb:3KWI|rcsb pdb:4NW2|rcsb pdb:4O45|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|dip:DIP-46282N refseq:NP_066544.1|ensembl:ENSG00000276368(gene)|ensembl:ENST00000333151(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:VyosjYP0De3Y+BRJoOxL/BcF3NU381517 rogid:tS29VG3PpglHaYbu0w5z7pGvYyI9606 intact-crc:22F020AA8AABB4AE|rigid:Or6MuwfnAOmS+LkHUJ6oA+7CIQk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03495 uniprotkb:Q7L7L0 intact:EBI-2548993|uniprotkb:Q1K9D5 intact:EBI-5325551|ensembl:ENSP00000355656|ensembl:ENSP00000493926|uniprotkb:B2R4S4 psi-mi:ns1_i72a2(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a3_human(display_long)|uniprotkb:H2AW(gene name)|psi-mi:H2AW(display_short)|uniprotkb:HIST3H2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:381517(i72a2)|taxid:381517("Influenza A virus (strain A/Udorn/307/1972 H3N2)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154909|imex:IM-17331-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0052038"(modulation by symbiont of host intracellular transport)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|interpro:IPR000256("Influenza non-structural protein (NS1)")|go:"GO:0046775"(suppression by virus of host cytokine production)|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:1AIL|rcsb pdb:1NS1|rcsb pdb:2KKZ|rcsb pdb:2RHK|rcsb pdb:3EE8|rcsb pdb:3EE9|rcsb pdb:3KWG|rcsb pdb:3KWI|rcsb pdb:4NW2|rcsb pdb:4O45|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|dip:DIP-46282N ensembl:ENSG00000181218(gene)|ensembl:ENSG00000284841(gene)|ensembl:ENST00000366695(transcript)|refseq:NP_254280.1|ensembl:ENST00000645741(transcript)|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-5689603|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q7L7L0|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000786"(nucleosome)|dip:DIP-48936N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:VyosjYP0De3Y+BRJoOxL/BcF3NU381517 rogid:t0RdR1SmUtmwRjtCS3uTyLGqSUI9606 intact-crc:22F020AA8AABB4AE|rigid:Or6MuwfnAOmS+LkHUJ6oA+7CIQk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03495 uniprotkb:P62807 intact:EBI-2548993|uniprotkb:Q1K9D5 intact:EBI-354552|uniprotkb:Q4VB69|uniprotkb:P02278|uniprotkb:Q3B872|uniprotkb:Q93078|uniprotkb:Q93080|ensembl:ENSP00000321744|ensembl:ENSP00000348924|ensembl:ENSP00000366962|ensembl:ENSP00000380180|ensembl:ENSP00000445633|ensembl:ENSP00000483237|ensembl:ENSP00000489317 psi-mi:ns1_i72a2(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2b1c_human(display_long)|uniprotkb:HIST1H2BG(gene name synonym)|uniprotkb:HIST1H2BI(gene name synonym)|uniprotkb:Histone H2B.1 A(gene name synonym)|uniprotkb:Histone H2B.a(gene name synonym)|uniprotkb:Histone H2B.g(gene name synonym)|uniprotkb:Histone H2B.h(gene name synonym)|uniprotkb:Histone H2B.k(gene name synonym)|uniprotkb:Histone H2B.l(gene name synonym)|uniprotkb:H2BC10(gene name)|psi-mi:H2BC10(display_short)|uniprotkb:H2BC4(gene name)|psi-mi:H2BC4(display_short)|uniprotkb:H2BC6(gene name)|psi-mi:H2BC6(display_short)|uniprotkb:H2BC7(gene name)|psi-mi:H2BC7(display_short)|uniprotkb:H2BC8(gene name)|psi-mi:H2BC8(display_short)|uniprotkb:H2BFA(gene name synonym)|uniprotkb:H2BFG(gene name synonym)|uniprotkb:H2BFH(gene name synonym)|uniprotkb:H2BFK(gene name synonym)|uniprotkb:H2BFL(gene name synonym)|uniprotkb:HIST1H2BC(gene name synonym)|uniprotkb:HIST1H2BE(gene name synonym)|uniprotkb:HIST1H2BF(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:381517(i72a2)|taxid:381517("Influenza A virus (strain A/Udorn/307/1972 H3N2)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154909|imex:IM-17331-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0052038"(modulation by symbiont of host intracellular transport)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|interpro:IPR000256("Influenza non-structural protein (NS1)")|go:"GO:0046775"(suppression by virus of host cytokine production)|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:1AIL|rcsb pdb:1NS1|rcsb pdb:2KKZ|rcsb pdb:2RHK|rcsb pdb:3EE8|rcsb pdb:3EE9|rcsb pdb:3KWG|rcsb pdb:3KWI|rcsb pdb:4NW2|rcsb pdb:4O45|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|dip:DIP-46282N refseq:NP_003509.1|refseq:NP_003513.1|refseq:NP_003514.2|refseq:NP_003516.1|refseq:NP_003517.2|refseq:NP_066407.1|rcsb pdb:7A08|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|rcsb pdb:6XJD|ensembl:ENSG00000180596(gene)|ensembl:ENSG00000273802(gene)|ensembl:ENSG00000274290(gene)|ensembl:ENSG00000277224(gene)|ensembl:ENSG00000278588(gene)|ensembl:ENST00000314332(transcript)|ensembl:ENST00000356530(transcript)|ensembl:ENST00000377733(transcript)|ensembl:ENST00000396984(transcript)|ensembl:ENST00000541790(transcript)|ensembl:ENST00000614097(transcript)|ensembl:ENST00000634910(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0042802"(identical protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P62807|rcsb pdb:5GT0|rcsb pdb:5KGF|rcsb pdb:6ACO|rcsb pdb:6C0W|rcsb pdb:6FML|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6X59|rcsb pdb:6X5A|dip:DIP-32890N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:VyosjYP0De3Y+BRJoOxL/BcF3NU381517 rogid:00sapwbWn8dtUr7qoPsRPUlL35A9606 intact-crc:22F020AA8AABB4AE|rigid:Or6MuwfnAOmS+LkHUJ6oA+7CIQk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03495 uniprotkb:P20671 intact:EBI-2548993|uniprotkb:Q1K9D5 intact:EBI-4407441|uniprotkb:A0PK91|uniprotkb:P57754|uniprotkb:Q6FGY6|ensembl:ENSP00000341094 psi-mi:ns1_i72a2(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a1d_human(display_long)|uniprotkb:H2AC7(gene name)|psi-mi:H2AC7(display_short)|uniprotkb:H2AFG(gene name synonym)|uniprotkb:HIST1H2AD(gene name synonym)|uniprotkb:Histone H2A.3(gene name synonym)|uniprotkb:Histone H2A/g(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:381517(i72a2)|taxid:381517("Influenza A virus (strain A/Udorn/307/1972 H3N2)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154909|imex:IM-17331-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0052038"(modulation by symbiont of host intracellular transport)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|interpro:IPR000256("Influenza non-structural protein (NS1)")|go:"GO:0046775"(suppression by virus of host cytokine production)|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:1AIL|rcsb pdb:1NS1|rcsb pdb:2KKZ|rcsb pdb:2RHK|rcsb pdb:3EE8|rcsb pdb:3EE9|rcsb pdb:3KWG|rcsb pdb:3KWI|rcsb pdb:4NW2|rcsb pdb:4O45|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|dip:DIP-46282N refseq:NP_066409.1|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000196866(gene)|ensembl:ENST00000341023(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:5GT3|rcsb pdb:6KBB|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:VyosjYP0De3Y+BRJoOxL/BcF3NU381517 rogid:Geraq+dGw3pvAAhgzzXQnYxDOOw9606 intact-crc:22F020AA8AABB4AE|rigid:Or6MuwfnAOmS+LkHUJ6oA+7CIQk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03495 uniprotkb:O60814 intact:EBI-2548993|uniprotkb:Q1K9D5 intact:EBI-4409738|uniprotkb:A8K7P7|uniprotkb:Q2VPI7|ensembl:ENSP00000349430 psi-mi:ns1_i72a2(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2b1k_human(display_long)|uniprotkb:H2BC12(gene name)|psi-mi:H2BC12(display_short)|uniprotkb:H2BFT(gene name synonym)|uniprotkb:HIRA-interacting protein 1(gene name synonym)|uniprotkb:HIRIP1(gene name synonym)|uniprotkb:HIST1H2BK(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:381517(i72a2)|taxid:381517("Influenza A virus (strain A/Udorn/307/1972 H3N2)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154909|imex:IM-17331-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0052038"(modulation by symbiont of host intracellular transport)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|interpro:IPR000256("Influenza non-structural protein (NS1)")|go:"GO:0046775"(suppression by virus of host cytokine production)|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:1AIL|rcsb pdb:1NS1|rcsb pdb:2KKZ|rcsb pdb:2RHK|rcsb pdb:3EE8|rcsb pdb:3EE9|rcsb pdb:3KWG|rcsb pdb:3KWI|rcsb pdb:4NW2|rcsb pdb:4O45|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|dip:DIP-46282N refseq:NP_542160.1|refseq:NP_001299582.1|dip:DIP-48935N|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000197903(gene)|ensembl:ENST00000356950(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:O60814|rcsb pdb:2CV5|rcsb pdb:6KE9|rcsb pdb:6L9H|rcsb pdb:6LE9|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6V92|rcsb pdb:6Y5D|rcsb pdb:7BWD|rcsb pdb:7DBP|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:VyosjYP0De3Y+BRJoOxL/BcF3NU381517 rogid:aBHcFUkMIdiiZov716H7kxmHzj09606 intact-crc:22F020AA8AABB4AE|rigid:Or6MuwfnAOmS+LkHUJ6oA+7CIQk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03495 uniprotkb:Q99879 intact:EBI-2548993|uniprotkb:Q1K9D5 intact:EBI-3893474|uniprotkb:Q6NWQ3|ensembl:ENSP00000477907 psi-mi:ns1_i72a2(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2b1m_human(display_long)|uniprotkb:H2BC14(gene name)|psi-mi:H2BC14(display_short)|uniprotkb:H2BFE(gene name synonym)|uniprotkb:HIST1H2BM(gene name synonym)|uniprotkb:Histone H2B.e(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:381517(i72a2)|taxid:381517("Influenza A virus (strain A/Udorn/307/1972 H3N2)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154909|imex:IM-17331-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0052038"(modulation by symbiont of host intracellular transport)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|interpro:IPR000256("Influenza non-structural protein (NS1)")|go:"GO:0046775"(suppression by virus of host cytokine production)|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:1AIL|rcsb pdb:1NS1|rcsb pdb:2KKZ|rcsb pdb:2RHK|rcsb pdb:3EE8|rcsb pdb:3EE9|rcsb pdb:3KWG|rcsb pdb:3KWI|rcsb pdb:4NW2|rcsb pdb:4O45|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|dip:DIP-46282N refseq:NP_003512.1|ensembl:ENSG00000273703(gene)|ensembl:ENST00000621112(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-912446|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:VyosjYP0De3Y+BRJoOxL/BcF3NU381517 rogid:ETy0Ge+X/+GWAlBGq+YpQLc+DoE9606 intact-crc:22F020AA8AABB4AE|rigid:Or6MuwfnAOmS+LkHUJ6oA+7CIQk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03495 uniprotkb:P0C0S8 intact:EBI-2548993|uniprotkb:Q1K9D5 intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538 psi-mi:ns1_i72a2(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:381517(i72a2)|taxid:381517("Influenza A virus (strain A/Udorn/307/1972 H3N2)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154909|imex:IM-17331-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0052038"(modulation by symbiont of host intracellular transport)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|interpro:IPR000256("Influenza non-structural protein (NS1)")|go:"GO:0046775"(suppression by virus of host cytokine production)|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:1AIL|rcsb pdb:1NS1|rcsb pdb:2KKZ|rcsb pdb:2RHK|rcsb pdb:3EE8|rcsb pdb:3EE9|rcsb pdb:3KWG|rcsb pdb:3KWI|rcsb pdb:4NW2|rcsb pdb:4O45|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|dip:DIP-46282N ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:VyosjYP0De3Y+BRJoOxL/BcF3NU381517 rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606 intact-crc:22F020AA8AABB4AE|rigid:Or6MuwfnAOmS+LkHUJ6oA+7CIQk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03495 uniprotkb:Q6FI13 intact:EBI-2548993|uniprotkb:Q1K9D5 intact:EBI-353620|uniprotkb:P20670|uniprotkb:B2R5F0|ensembl:ENSP00000358155|ensembl:ENSP00000475814 psi-mi:ns1_i72a2(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a2a_human(display_long)|uniprotkb:H2AC18(gene name)|psi-mi:H2AC18(display_short)|uniprotkb:H2AC19(gene name)|psi-mi:H2AC19(display_short)|uniprotkb:H2A-clustered histone 18(gene name synonym)|uniprotkb:H2A-clustered histone 19(gene name synonym)|uniprotkb:H2AFO(gene name synonym)|uniprotkb:HIST2H2AA(gene name synonym)|uniprotkb:HIST2H2AA3(gene name synonym)|uniprotkb:HIST2H2AA4(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/o(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:381517(i72a2)|taxid:381517("Influenza A virus (strain A/Udorn/307/1972 H3N2)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154909|imex:IM-17331-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0052038"(modulation by symbiont of host intracellular transport)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|interpro:IPR000256("Influenza non-structural protein (NS1)")|go:"GO:0046775"(suppression by virus of host cytokine production)|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:1AIL|rcsb pdb:1NS1|rcsb pdb:2KKZ|rcsb pdb:2RHK|rcsb pdb:3EE8|rcsb pdb:3EE9|rcsb pdb:3KWG|rcsb pdb:3KWI|rcsb pdb:4NW2|rcsb pdb:4O45|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|dip:DIP-46282N refseq:NP_001035807.1|refseq:NP_003507.1|ensembl:ENSG00000203812(gene)|ensembl:ENSG00000272196(gene)|ensembl:ENST00000369159(transcript)|ensembl:ENST00000607355(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6Y5D|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|dip:DIP-33167N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:VyosjYP0De3Y+BRJoOxL/BcF3NU381517 rogid:PMuIm2XMN5q4wk+wYJ94mmnCe4w9606 intact-crc:22F020AA8AABB4AE|rigid:Or6MuwfnAOmS+LkHUJ6oA+7CIQk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03495 uniprotkb:P57053 intact:EBI-2548993|uniprotkb:Q1K9D5 intact:EBI-2880265|ensembl:ENSP00000481622|uniprotkb:A0AVF9|uniprotkb:Q5R2W0 psi-mi:ns1_i72a2(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2bfs_human(display_long)|uniprotkb:H2BS1(gene name)|psi-mi:H2BS1(display_short)|uniprotkb:H2B.S histone 1(gene name synonym)|uniprotkb:H2BFS(gene name synonym)|uniprotkb:Histone H2B.s(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:381517(i72a2)|taxid:381517("Influenza A virus (strain A/Udorn/307/1972 H3N2)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154909|imex:IM-17331-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0052038"(modulation by symbiont of host intracellular transport)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|interpro:IPR000256("Influenza non-structural protein (NS1)")|go:"GO:0046775"(suppression by virus of host cytokine production)|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:1AIL|rcsb pdb:1NS1|rcsb pdb:2KKZ|rcsb pdb:2RHK|rcsb pdb:3EE8|rcsb pdb:3EE9|rcsb pdb:3KWG|rcsb pdb:3KWI|rcsb pdb:4NW2|rcsb pdb:4O45|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|dip:DIP-46282N ensembl:ENSG00000234289(gene)|ensembl:ENST00000599962(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0021762"(substantia nigra development)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-427359|refseq:XP_006723981.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:VyosjYP0De3Y+BRJoOxL/BcF3NU381517 rogid:x8Ryb6Tm0nfhcmsoTX5h5ZRsN7g9606 intact-crc:22F020AA8AABB4AE|rigid:Or6MuwfnAOmS+LkHUJ6oA+7CIQk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03495 uniprotkb:P58876 intact:EBI-2548993|uniprotkb:Q1K9D5 intact:EBI-4409942|ensembl:ENSP00000289316|ensembl:ENSP00000367008 psi-mi:ns1_i72a2(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2b1d_human(display_long)|uniprotkb:Histone H2B.b(gene name synonym)|uniprotkb:H2BC5(gene name)|psi-mi:H2BC5(display_short)|uniprotkb:H2B-clustered histone 5(gene name synonym)|uniprotkb:H2BFB(gene name synonym)|uniprotkb:HIRA-interacting protein 2(gene name synonym)|uniprotkb:HIRIP2(gene name synonym)|uniprotkb:HIST1H2BD(gene name synonym)|uniprotkb:Histone H2B.1 B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:381517(i72a2)|taxid:381517("Influenza A virus (strain A/Udorn/307/1972 H3N2)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154909|imex:IM-17331-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0052038"(modulation by symbiont of host intracellular transport)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|interpro:IPR000256("Influenza non-structural protein (NS1)")|go:"GO:0046775"(suppression by virus of host cytokine production)|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:1AIL|rcsb pdb:1NS1|rcsb pdb:2KKZ|rcsb pdb:2RHK|rcsb pdb:3EE8|rcsb pdb:3EE9|rcsb pdb:3KWG|rcsb pdb:3KWI|rcsb pdb:4NW2|rcsb pdb:4O45|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|dip:DIP-46282N refseq:NP_066407.1|refseq:NP_619790.1|ensembl:ENSG00000158373(gene)|ensembl:ENST00000289316(transcript)|ensembl:ENST00000377777(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P58876|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005634"(nucleus) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:VyosjYP0De3Y+BRJoOxL/BcF3NU381517 rogid:07VBw5MCphdkMydMOPSjVqpGriI9606 intact-crc:22F020AA8AABB4AE|rigid:Or6MuwfnAOmS+LkHUJ6oA+7CIQk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03495 uniprotkb:Q93079 intact:EBI-2548993|uniprotkb:Q1K9D5 intact:EBI-352469|uniprotkb:Q4VB74|uniprotkb:B2R541|ensembl:ENSP00000479169 psi-mi:ns1_i72a2(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2b1h_human(display_long)|uniprotkb:H2BC9(gene name)|psi-mi:H2BC9(display_short)|uniprotkb:H2B-clustered histone 9(gene name synonym)|uniprotkb:H2BFJ(gene name synonym)|uniprotkb:HIST1H2BH(gene name synonym)|uniprotkb:Histone H2B.j(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:381517(i72a2)|taxid:381517("Influenza A virus (strain A/Udorn/307/1972 H3N2)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154909|imex:IM-17331-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0052038"(modulation by symbiont of host intracellular transport)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|interpro:IPR000256("Influenza non-structural protein (NS1)")|go:"GO:0046775"(suppression by virus of host cytokine production)|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:1AIL|rcsb pdb:1NS1|rcsb pdb:2KKZ|rcsb pdb:2RHK|rcsb pdb:3EE8|rcsb pdb:3EE9|rcsb pdb:3KWG|rcsb pdb:3KWI|rcsb pdb:4NW2|rcsb pdb:4O45|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|dip:DIP-46282N refseq:NP_003515.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|ensembl:ENSG00000275713(gene)|ensembl:ENST00000619466(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0097677"(STAT family protein binding)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:VyosjYP0De3Y+BRJoOxL/BcF3NU381517 rogid:W+7KkrtV9xv7ELLxmJFnI4LQoME9606 intact-crc:22F020AA8AABB4AE|rigid:Or6MuwfnAOmS+LkHUJ6oA+7CIQk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03495 uniprotkb:Q9BTM1 intact:EBI-2548993|uniprotkb:Q1K9D5 intact:EBI-4398590|uniprotkb:Q9NV63|ensembl:ENSP00000373730|ensembl:ENSP00000438553 psi-mi:ns1_i72a2(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2aj_human(display_long)|uniprotkb:H2AJ(gene name)|psi-mi:H2AJ(display_short)|uniprotkb:H2AFJ(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:381517(i72a2)|taxid:381517("Influenza A virus (strain A/Udorn/307/1972 H3N2)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154909|imex:IM-17331-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0052038"(modulation by symbiont of host intracellular transport)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|interpro:IPR000256("Influenza non-structural protein (NS1)")|go:"GO:0046775"(suppression by virus of host cytokine production)|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:1AIL|rcsb pdb:1NS1|rcsb pdb:2KKZ|rcsb pdb:2RHK|rcsb pdb:3EE8|rcsb pdb:3EE9|rcsb pdb:3KWG|rcsb pdb:3KWI|rcsb pdb:4NW2|rcsb pdb:4O45|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|dip:DIP-46282N refseq:NP_808760.1|ensembl:ENSG00000246705(gene)|ensembl:ENST00000389078(transcript)|ensembl:ENST00000544848(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:4EDU|rcsb pdb:6K60|rcsb pdb:6KVD|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-8939236 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:VyosjYP0De3Y+BRJoOxL/BcF3NU381517 rogid:g6br63FeM17yJRfQI3GnmoM0vbc9606 intact-crc:22F020AA8AABB4AE|rigid:Or6MuwfnAOmS+LkHUJ6oA+7CIQk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03495 uniprotkb:P22492 intact:EBI-2548993|uniprotkb:Q1K9D5 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 psi-mi:ns1_i72a2(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:381517(i72a2)|taxid:381517("Influenza A virus (strain A/Udorn/307/1972 H3N2)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154909|imex:IM-17331-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0052038"(modulation by symbiont of host intracellular transport)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|interpro:IPR000256("Influenza non-structural protein (NS1)")|go:"GO:0046775"(suppression by virus of host cytokine production)|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:1AIL|rcsb pdb:1NS1|rcsb pdb:2KKZ|rcsb pdb:2RHK|rcsb pdb:3EE8|rcsb pdb:3EE9|rcsb pdb:3KWG|rcsb pdb:3KWI|rcsb pdb:4NW2|rcsb pdb:4O45|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|dip:DIP-46282N refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:VyosjYP0De3Y+BRJoOxL/BcF3NU381517 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 intact-crc:22F020AA8AABB4AE|rigid:Or6MuwfnAOmS+LkHUJ6oA+7CIQk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03495 uniprotkb:Q96KK5 intact:EBI-2548993|uniprotkb:Q1K9D5 intact:EBI-6147668|ensembl:ENSP00000366679 psi-mi:ns1_i72a2(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a1h_human(display_long)|uniprotkb:H2AC12(gene name)|psi-mi:H2AC12(display_short)|uniprotkb:H2A-clustered histone 12(gene name synonym)|uniprotkb:HIST1H2AH(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:Histone H2A/s(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:381517(i72a2)|taxid:381517("Influenza A virus (strain A/Udorn/307/1972 H3N2)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154909|imex:IM-17331-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0052038"(modulation by symbiont of host intracellular transport)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|interpro:IPR000256("Influenza non-structural protein (NS1)")|go:"GO:0046775"(suppression by virus of host cytokine production)|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:1AIL|rcsb pdb:1NS1|rcsb pdb:2KKZ|rcsb pdb:2RHK|rcsb pdb:3EE8|rcsb pdb:3EE9|rcsb pdb:3KWG|rcsb pdb:3KWI|rcsb pdb:4NW2|rcsb pdb:4O45|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|dip:DIP-46282N refseq:NP_542163.1|dip:DIP-61699N|ensembl:ENSG00000274997(gene)|ensembl:ENST00000377459(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:VyosjYP0De3Y+BRJoOxL/BcF3NU381517 rogid:Oa322n+evy8Cu0E9cWTEdYwQPKM9606 intact-crc:22F020AA8AABB4AE|rigid:Or6MuwfnAOmS+LkHUJ6oA+7CIQk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03495 uniprotkb:Q99877 intact:EBI-2548993|uniprotkb:Q1K9D5 intact:EBI-744423|uniprotkb:Q494S8|uniprotkb:Q96FB7|uniprotkb:B2R5L4|ensembl:ENSP00000446031|ensembl:ENSP00000483903 psi-mi:ns1_i72a2(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2b1n_human(display_long)|uniprotkb:H2BC15(gene name)|psi-mi:H2BC15(display_short)|uniprotkb:H2BFD(gene name synonym)|uniprotkb:HIST1H2BN(gene name synonym)|uniprotkb:Histone H2B.d(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:381517(i72a2)|taxid:381517("Influenza A virus (strain A/Udorn/307/1972 H3N2)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154909|imex:IM-17331-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0052038"(modulation by symbiont of host intracellular transport)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|interpro:IPR000256("Influenza non-structural protein (NS1)")|go:"GO:0046775"(suppression by virus of host cytokine production)|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:1AIL|rcsb pdb:1NS1|rcsb pdb:2KKZ|rcsb pdb:2RHK|rcsb pdb:3EE8|rcsb pdb:3EE9|rcsb pdb:3KWG|rcsb pdb:3KWI|rcsb pdb:4NW2|rcsb pdb:4O45|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|dip:DIP-46282N refseq:NP_003511.1|ensembl:ENSG00000233822(gene)|ensembl:ENST00000449538(transcript)|ensembl:ENST00000612898(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:VyosjYP0De3Y+BRJoOxL/BcF3NU381517 rogid:nGZETothwO57PuE11M5ogikaZkM9606 intact-crc:22F020AA8AABB4AE|rigid:Or6MuwfnAOmS+LkHUJ6oA+7CIQk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:Q02539 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-932603|uniprotkb:Q3MJ34|ensembl:ENSP00000244573 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h11_human(display_long)|uniprotkb:H1-1(gene name)|psi-mi:H1-1(display_short)|uniprotkb:H1F1(gene name synonym)|uniprotkb:HIST1H1A(gene name synonym)|uniprotkb:Histone H1a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_005316.1|ensembl:ENSG00000124610(gene)|ensembl:ENST00000244573(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q02539|reactome:R-HSA-140342|reactome:R-HSA-2559584 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:4u8P8jFM3onWx43+SxL320urjhk9606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:P31943 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168|ensembl:ENSP00000377082|ensembl:ENSP00000397797|ensembl:ENSP00000492076|ensembl:ENSP00000495786 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_005511.1|refseq:NP_001244222.1|ensembl:ENSG00000169045(gene)|ensembl:ENSG00000284254(gene)|ensembl:ENST00000356731(transcript)|ensembl:ENST00000393432(transcript)|ensembl:ENST00000442819(transcript)|ensembl:ENST00000638505(transcript)|ensembl:ENST00000643310(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:O00629 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-396343|uniprotkb:O00190|intact:EBI-28976443|ensembl:ENSP00000334373|uniprotkb:A8K4S6|uniprotkb:D3DNM2 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:ima3_human(display_long)|uniprotkb:KPNA4(gene name)|psi-mi:KPNA4(display_short)|uniprotkb:QIP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-4(gene name synonym)|uniprotkb:Importin alpha Q1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_002259.1|ensembl:ENSG00000186432(gene)|ensembl:ENST00000334256(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00629|rcsb pdb:4UAE|rcsb pdb:5TBK|rcsb pdb:5XZX|rcsb pdb:6BVV|rcsb pdb:6BVZ|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|rcsb pdb:6WX8|rcsb pdb:7JJL|reactome:R-HSA-1169408|reactome:R-HSA-168276|ensembl:ENSP00000334373|dip:DIP-32982N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:/cng/xZ42E2juzHNOpuQTP+amx89606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:Q16777 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-5325566|ensembl:ENSP00000332194|uniprotkb:Q6DRA7|uniprotkb:Q8IUE5 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a2c_human(display_long)|uniprotkb:H2AC20(gene name)|psi-mi:H2AC20(display_short)|uniprotkb:H2A-clustered histone 20(gene name synonym)|uniprotkb:H2AFQ(gene name synonym)|uniprotkb:HIST2H2AC(gene name synonym)|uniprotkb:Histone H2A-GL101(gene name synonym)|uniprotkb:Histone H2A/q(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-5689603|ensembl:ENSG00000184260(gene)|ensembl:ENST00000331380(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q16777|rcsb pdb:6Y5E|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|refseq:NP_003508.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:Wejrpp9wK3GvA4ahJDVyEH+cwlQ9606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:P22492 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:P62805 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:O00505 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-358297|intact:EBI-28976892|ensembl:ENSP00000261667|uniprotkb:O00191|uniprotkb:O43195|uniprotkb:Q96AA7|uniprotkb:Q5JVM9|intact:EBI-742146|uniprotkb:Q8IYQ9 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:ima4_human(display_long)|uniprotkb:KPNA3(gene name)|psi-mi:KPNA3(display_short)|uniprotkb:QIP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym)|uniprotkb:SRP1-gamma(gene name synonym)|uniprotkb:Importin alpha Q2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000102753(gene)|ensembl:ENST00000261667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043657"(host cell)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000225(Armadillo)|refseq:NP_002258.2|ensembl:ENSP00000261667|dip:DIP-27586N|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00505|reactome:R-HSA-1169408|reactome:R-HSA-168276 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:kx/oTYWMYG7dhwJHvr1POLD6FTU9606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:P62829 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-353303|uniprotkb:P23131|uniprotkb:Q3SWV7|uniprotkb:P24048|uniprotkb:Q29246|uniprotkb:Q6P5S1|ensembl:ENSP00000377865|ensembl:ENSP00000420311 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:rl23_human(display_long)|uniprotkb:RPL23(gene name)|psi-mi:RPL23(display_short)|uniprotkb:60S ribosomal protein L17(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|reactome:R-HSA-9010553|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|refseq:NP_000969.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000218(Ribosomal protein L14b/L23e)|interpro:IPR019972|interpro:IPR036853|mint:P62829|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|ensembl:ENSG00000125691(gene)|ensembl:ENST00000394332(transcript)|ensembl:ENST00000479035(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0005730"(nucleolus)|dip:DIP-33156N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:TiSVU2W4+lkwf12eb4+vG6IFlZA9606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:P07437 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:P22626 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:Q99729 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:Q6T4R5 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-6147838|uniprotkb:Q5J7Q1|uniprotkb:Q68DR5|uniprotkb:Q5J7Q0|uniprotkb:B7ZVX8|uniprotkb:E2DH69|ensembl:ENSP00000502262 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:nhs_human(display_long)|uniprotkb:NHS(gene name)|psi-mi:NHS(display_short)|uniprotkb:Congenital cataracts and dental anomalies protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_001278796.1|refseq:NP_001278797.1|refseq:NP_001129496.1|refseq:NP_938011.1|ensembl:ENSG00000188158(gene)|ensembl:ENST00000676302(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|interpro:IPR024845|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:HqtL7E5pe3UkCCbArDU0XY+HAW49606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:Q96KK5 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-6147668|ensembl:ENSP00000366679 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a1h_human(display_long)|uniprotkb:H2AC12(gene name)|psi-mi:H2AC12(display_short)|uniprotkb:H2A-clustered histone 12(gene name synonym)|uniprotkb:HIST1H2AH(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:Histone H2A/s(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_542163.1|dip:DIP-61699N|ensembl:ENSG00000274997(gene)|ensembl:ENST00000377459(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:Oa322n+evy8Cu0E9cWTEdYwQPKM9606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:Q93077 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-725259|uniprotkb:O00775|uniprotkb:O00776|uniprotkb:O00777|uniprotkb:O00778|uniprotkb:Q540R1|uniprotkb:B2R4F7|ensembl:ENSP00000321389|ensembl:ENSP00000367022|ensembl:ENSP00000473534 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a1c_human(display_long)|uniprotkb:H2AC6(gene name)|psi-mi:H2AC6(display_short)|uniprotkb:H2A-clustered histone 6(gene name synonym)|uniprotkb:H2AFL(gene name synonym)|uniprotkb:HIST1H2AC(gene name synonym)|uniprotkb:Histone H2A/l(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_003503.1|ensembl:ENSG00000180573(gene)|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENST00000314088(transcript)|ensembl:ENST00000377791(transcript)|ensembl:ENST00000602637(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|rcsb pdb:6C0W|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:7A08|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|interpro:IPR032458 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:m00IdooZksbNGKHSsaVvGFVpcko9606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:P04908 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:4Qno1mMYZB6FdNoojrzulWLVq849606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:P35637 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-400434|uniprotkb:Q9H4A8|ensembl:ENSP00000254108 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:fus_human(display_long)|uniprotkb:FUS(gene name)|psi-mi:FUS(display_short)|uniprotkb:TLS(gene name synonym)|uniprotkb:Oncogene FUS(gene name synonym)|uniprotkb:Oncogene TLS(gene name synonym)|uniprotkb:Translocated in liposarcoma protein(gene name synonym)|uniprotkb:POMp75(gene name synonym)|uniprotkb:75 kDa DNA-pairing protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_001164105.1|refseq:NP_004951.1|ensembl:ENSG00000089280(gene)|ensembl:ENST00000254108(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008380"(RNA splicing)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044327"(dendritic spine head)|go:"GO:0046872"(metal ion binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034459|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:P35637|rcsb pdb:2LA6|rcsb pdb:2LCW|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:5W3N|rcsb pdb:5XRR|rcsb pdb:5XSG|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:6BWZ|rcsb pdb:6BXV|rcsb pdb:6BZP|rcsb pdb:6G99|rcsb pdb:6GBM|rcsb pdb:6KJ1|rcsb pdb:6KJ2|rcsb pdb:6KJ3|rcsb pdb:6KJ4|rcsb pdb:6SNJ|rcsb pdb:6XFM|rcsb pdb:7CYL|reactome:R-HSA-72163|dip:DIP-29857N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:HUP4fGXQyJnm5CFTuwjTpiucZOc9606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:P11021 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:Q99878 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-6147676|uniprotkb:Q5JXQ5|uniprotkb:A2RUU6|ensembl:ENSP00000328484 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a1j_human(display_long)|uniprotkb:H2AC14(gene name)|psi-mi:H2AC14(display_short)|uniprotkb:H2AFE(gene name synonym)|uniprotkb:HIST1H2AJ(gene name synonym)|uniprotkb:Histone H2A/e(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_066544.1|ensembl:ENSG00000276368(gene)|ensembl:ENST00000333151(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:tS29VG3PpglHaYbu0w5z7pGvYyI9606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:P12277 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-357706|uniprotkb:Q2LE07|uniprotkb:A8K236|uniprotkb:B2R5R4|uniprotkb:Q6FG40|uniprotkb:Q9UC66|ensembl:ENSP00000299198 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:kcrb_human(display_long)|uniprotkb:CKB(gene name)|psi-mi:CKB(display_short)|uniprotkb:CKBB(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:Brain creatine kinase(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_001814.2|go:"GO:0005829"(cytosol)|ensembl:ENSG00000166165(gene)|ensembl:ENST00000348956(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12277|rcsb pdb:3B6R|rcsb pdb:3DRB|rcsb pdb:3DRE|rcsb pdb:6V9H|go:"GO:0021762"(substantia nigra development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|reactome:R-HSA-71288|reactome:R-HSA-9696264|dip:DIP-52968N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:WLRnU8sRUfJQoaPY0edGi9xiR+g9606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:Q6FI13 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-353620|uniprotkb:P20670|uniprotkb:B2R5F0|ensembl:ENSP00000358155|ensembl:ENSP00000475814 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a2a_human(display_long)|uniprotkb:H2AC18(gene name)|psi-mi:H2AC18(display_short)|uniprotkb:H2AC19(gene name)|psi-mi:H2AC19(display_short)|uniprotkb:H2A-clustered histone 18(gene name synonym)|uniprotkb:H2A-clustered histone 19(gene name synonym)|uniprotkb:H2AFO(gene name synonym)|uniprotkb:HIST2H2AA(gene name synonym)|uniprotkb:HIST2H2AA3(gene name synonym)|uniprotkb:HIST2H2AA4(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/o(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_001035807.1|refseq:NP_003507.1|ensembl:ENSG00000203812(gene)|ensembl:ENSG00000272196(gene)|ensembl:ENST00000369159(transcript)|ensembl:ENST00000607355(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6Y5D|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|dip:DIP-33167N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:PMuIm2XMN5q4wk+wYJ94mmnCe4w9606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:P12036 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-2880271|uniprotkb:Q9UQ14|uniprotkb:Q9UJS7|uniprotkb:Q96HF8|uniprotkb:B4DYY4|ensembl:ENSP00000311997 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:nfh_human(display_long)|uniprotkb:NEFH(gene name)|psi-mi:NEFH(display_short)|uniprotkb:KIAA0845(gene name synonym)|uniprotkb:NFH(gene name synonym)|uniprotkb:200 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament triplet H protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_066554.2|ensembl:ENSG00000100285(gene)|ensembl:ENST00000310624(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005883"(neurofilament)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0061564"(axon development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR010790(Protein of unknown function DUF1388)|interpro:IPR018039|interpro:IPR033183|interpro:IPR039008|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:TXMrn6SWBHIYQY1loZfVvMo9PtU9606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:P52630 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-1546963|uniprotkb:Q16430|uniprotkb:Q16431|uniprotkb:Q9UDL4|intact:EBI-10989287|uniprotkb:B4DLC7|uniprotkb:G3V2M6|ensembl:ENSP00000315768 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:stat2_human(display_long)|uniprotkb:p113(gene name synonym)|uniprotkb:STAT2(gene name)|psi-mi:STAT2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_005410.1|refseq:NP_938146.1|dip:DIP-38511N|ensembl:ENSG00000170581(gene)|ensembl:ENST00000314128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0090140"(regulation of mitochondrial fission)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022756|interpro:IPR035854|interpro:IPR036535|interpro:IPR036860|mint:P52630|rcsb pdb:2KA4|rcsb pdb:6UX2|rcsb pdb:6WCZ|reactome:R-HSA-8854691|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9679191 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:uA0lxm5vmrLClQRP7NItd0/u4Ko9606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:Q7L7L0 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-5325551|ensembl:ENSP00000355656|ensembl:ENSP00000493926|uniprotkb:B2R4S4 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a3_human(display_long)|uniprotkb:H2AW(gene name)|psi-mi:H2AW(display_short)|uniprotkb:HIST3H2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000181218(gene)|ensembl:ENSG00000284841(gene)|ensembl:ENST00000366695(transcript)|refseq:NP_254280.1|ensembl:ENST00000645741(transcript)|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-5689603|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q7L7L0|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000786"(nucleosome)|dip:DIP-48936N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:t0RdR1SmUtmwRjtCS3uTyLGqSUI9606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:P27348 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081|ensembl:ENSP00000371267 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_006817.1|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|ensembl:ENSG00000134308(gene)|ensembl:ENST00000238081(transcript)|ensembl:ENST00000381844(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|dip:DIP-27584N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:P20671 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-4407441|uniprotkb:A0PK91|uniprotkb:P57754|uniprotkb:Q6FGY6|ensembl:ENSP00000341094 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a1d_human(display_long)|uniprotkb:H2AC7(gene name)|psi-mi:H2AC7(display_short)|uniprotkb:H2AFG(gene name synonym)|uniprotkb:HIST1H2AD(gene name synonym)|uniprotkb:Histone H2A.3(gene name synonym)|uniprotkb:Histone H2A/g(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_066409.1|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000196866(gene)|ensembl:ENST00000341023(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:5GT3|rcsb pdb:6KBB|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:Geraq+dGw3pvAAhgzzXQnYxDOOw9606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:Q9BQE3 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:P55795 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-352823|ensembl:ENSP00000361927|uniprotkb:Q9HHA7|uniprotkb:A1L400 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:hnrh2_human(display_long)|uniprotkb:HNRNPH2(gene name)|psi-mi:HNRNPH2(display_short)|uniprotkb:FTP3(gene name synonym)|uniprotkb:HNRPH2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein H'(gene name synonym)|uniprotkb:FTP-3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000126945(gene)|ensembl:ENST00000316594(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P55795|rcsb pdb:1WEZ|rcsb pdb:1WG5|rcsb pdb:6DG1|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001027565.1|refseq:NP_062543.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:811j5syFsbk/QSaZv/ag9QsFUEQ9606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:Q9BTM1 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-4398590|uniprotkb:Q9NV63|ensembl:ENSP00000373730|ensembl:ENSP00000438553 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2aj_human(display_long)|uniprotkb:H2AJ(gene name)|psi-mi:H2AJ(display_short)|uniprotkb:H2AFJ(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_808760.1|ensembl:ENSG00000246705(gene)|ensembl:ENST00000389078(transcript)|ensembl:ENST00000544848(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:4EDU|rcsb pdb:6K60|rcsb pdb:6KVD|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-8939236 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:g6br63FeM17yJRfQI3GnmoM0vbc9606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:P63104 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:P42224 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-1057697|uniprotkb:Q53S88|uniprotkb:Q53XW4|uniprotkb:B2RCA0|uniprotkb:Q9UDL5|uniprotkb:A8K989|uniprotkb:D2KFR8|uniprotkb:Q68D00|uniprotkb:D3DPI7|ensembl:ENSP00000354394|ensembl:ENSP00000386244|ensembl:ENSP00000388240|ensembl:ENSP00000438703 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:stat1_human(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)|uniprotkb:Transcription factor ISGF-3 components p91/p84(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_009330.1|refseq:NP_644671.1|rcsb pdb:1YVL|rcsb pdb:2KA6|rcsb pdb:3WWT|reactome:R-HSA-1059683|reactome:R-HSA-1169408|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8939902|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9013508|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-909733|rcsb pdb:1BF5|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-912694|refseq:XP_006712781.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016922"(nuclear receptor binding)|ensembl:ENSG00000115415(gene)|ensembl:ENST00000361099(transcript)|ensembl:ENST00000409465(transcript)|ensembl:ENST00000415035(transcript)|ensembl:ENST00000540176(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051607"(defense response to virus)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0061326"(renal tubule development)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022752|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|interpro:IPR035859|interpro:IPR036535|interpro:IPR036860|interpro:IPR038295|mint:P42224|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042393"(histone binding)|dip:DIP-46140N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:a2ZnhdFZkctbjaXLpsYNJ3q5Cv49606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:P31942 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-711437|uniprotkb:Q9NPI4|uniprotkb:Q9UFU4|uniprotkb:Q9Y4J5|uniprotkb:Q9BSX1|uniprotkb:Q9NP53|uniprotkb:Q9NP96|uniprotkb:Q9NPA7|ensembl:ENSP00000265866|uniprotkb:A8K682|uniprotkb:B3KRE1 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:hnrh3_human(display_long)|uniprotkb:HNRNPH3(gene name)|psi-mi:HNRNPH3(display_short)|uniprotkb:HNRPH3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein 2H9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000096746(gene)|ensembl:ENST00000265866(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034969|interpro:IPR034970|interpro:IPR035979|mint:P31942|refseq:NP_036339.1|refseq:NP_067676.2|refseq:NP_001309363.1|refseq:NP_001309365.1|refseq:NP_001309366.1|refseq:NP_001309367.1|refseq:NP_001309368.1|refseq:NP_001309369.1|refseq:NP_001309370.1|refseq:NP_001309374.1|refseq:NP_001309375.1|refseq:NP_001309376.1|refseq:NP_001309377.1|refseq:NP_001309378.1|refseq:XP_016871657.1|refseq:XP_016871658.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:iJGBIhPXnQIIFQmgxWB1WjwVXSY9606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q997F2 uniprotkb:P0C0S8 intact:EBI-6147833|uniprotkb:Q8QU01 intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538 psi-mi:v_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6154981|imex:IM-17331-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q997F2|interpro:IPR024279|refseq:NP_112023.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:91tF+j3UAen7MFN3EfWx+YffknI121791 rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606 intact-crc:3051FCBE59F3E4D3|rigid:QFvrspwV0LcmTcGNl6th9BVVwNA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D2CFJ1 uniprotkb:Q02539 intact:EBI-6147949 intact:EBI-932603|uniprotkb:Q3MJ34|ensembl:ENSP00000244573 psi-mi:d2cfj1_9flav(display_long) psi-mi:h11_human(display_long)|uniprotkb:H1-1(gene name)|psi-mi:H1-1(display_short)|uniprotkb:H1F1(gene name synonym)|uniprotkb:HIST1H1A(gene name synonym)|uniprotkb:Histone H1a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:54315(bvdv-2)|taxid:54315(Bovine viral diarrhea virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155083|imex:IM-17331-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR042542|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity) refseq:NP_005316.1|ensembl:ENSG00000124610(gene)|ensembl:ENST00000244573(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q02539|reactome:R-HSA-140342|reactome:R-HSA-2559584 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:h4N69bizWQGHiHxL90Y0oX65xaY54315 rogid:4u8P8jFM3onWx43+SxL320urjhk9606 intact-crc:2411765E0AB50A5D|rigid:Hu4O80mmGgXQHT9fhJLzk9KpdFo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D2CFJ1 uniprotkb:Q15369 intact:EBI-6147949 intact:EBI-301231|uniprotkb:Q567Q6|ensembl:ENSP00000284811|ensembl:ENSP00000428074|ensembl:ENSP00000428171|ensembl:ENSP00000428334|ensembl:ENSP00000429596|ensembl:ENSP00000429906|ensembl:ENSP00000478121|uniprotkb:E5RGD9 psi-mi:d2cfj1_9flav(display_long) psi-mi:eloc_human(display_long)|uniprotkb:ELOC(gene name)|psi-mi:ELOC(display_short)|uniprotkb:Elongin 15 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit C(gene name synonym)|uniprotkb:SIII p15(gene name synonym)|uniprotkb:TCEB1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:54315(bvdv-2)|taxid:54315(Bovine viral diarrhea virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155083|imex:IM-17331-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR042542|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity) refseq:NP_005639.1|refseq:NP_001191786.1|refseq:NP_001191787.1|refseq:NP_001191788.1|refseq:NP_001191789.1|refseq:NP_001191790.1|refseq:NP_001191791.1|refseq:NP_001191792.1|refseq:NP_001191793.1|ensembl:ENSG00000154582(gene)|ensembl:ENST00000284811(transcript)|ensembl:ENST00000518127(transcript)|ensembl:ENST00000519487(transcript)|ensembl:ENST00000520242(transcript)|ensembl:ENST00000522337(transcript)|ensembl:ENST00000523815(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|mint:Q15369|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|ensembl:ENST00000622804(transcript)|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:4WQO|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6GFY|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7N|rcsb pdb:6SIS|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-167200|refseq:XP_011515882.1|refseq:XP_011515883.1|dip:DIP-29571N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:h4N69bizWQGHiHxL90Y0oX65xaY54315 rogid:Ngvkh3YoddZoutF3Vgwdi2b6xz49606 intact-crc:2411765E0AB50A5D|rigid:Hu4O80mmGgXQHT9fhJLzk9KpdFo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D2CFJ1 uniprotkb:A7E2V4 intact:EBI-6147949 intact:EBI-947995|uniprotkb:Q17RS8|uniprotkb:Q2TAB8|uniprotkb:Q6P439|uniprotkb:Q8IW81|uniprotkb:Q8NB34|uniprotkb:Q9H8F3|uniprotkb:O94987|uniprotkb:B2RP37|ensembl:ENSP00000474748 psi-mi:d2cfj1_9flav(display_long) psi-mi:zswm8_human(display_long)|uniprotkb:ZSWIM8(gene name)|psi-mi:ZSWIM8(display_short)|uniprotkb:KIAA0913(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:54315(bvdv-2)|taxid:54315(Bovine viral diarrhea virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155083|imex:IM-17331-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR042542|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity) refseq:NP_001229416.1|refseq:NP_001229417.1|refseq:NP_055852.2|refseq:XP_006717788.1|ensembl:ENSG00000214655(gene)|ensembl:ENST00000605216(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1902667"(regulation of axon guidance)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|go:"GO:2000627"(positive regulation of miRNA catabolic process)|interpro:IPR007527(Zinc finger, SWIM-type)|reactome:R-HSA-9010553 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:h4N69bizWQGHiHxL90Y0oX65xaY54315 rogid:L/Zc7H24cEC7qtYp34nahN0pKEc9606 intact-crc:2411765E0AB50A5D|rigid:Hu4O80mmGgXQHT9fhJLzk9KpdFo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D2CFJ1 uniprotkb:Q9BRZ2 intact:EBI-6147949 intact:EBI-1048636|uniprotkb:Q6PJS5|uniprotkb:Q86VT6|uniprotkb:Q8N2H8|uniprotkb:Q8NAC0|uniprotkb:Q9H031|intact:EBI-2129929|ensembl:ENSP00000305161 psi-mi:d2cfj1_9flav(display_long) psi-mi:tri56_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase TRIM56(gene name synonym)|uniprotkb:RING finger protein 109(gene name synonym)|uniprotkb:TRIM56(gene name)|psi-mi:TRIM56(display_short)|uniprotkb:RNF109(gene name synonym)|uniprotkb:Tripartite motif-containing protein 56(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:54315(bvdv-2)|taxid:54315(Bovine viral diarrhea virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155083|imex:IM-17331-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR042542|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity) refseq:NP_112223.1|refseq:XP_011514891.1|ensembl:ENSG00000169871(gene)|ensembl:ENST00000306085(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034340"(response to type I interferon)|go:"GO:0045087"(innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|rcsb pdb:5JW7|reactome:R-HSA-3134975 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:h4N69bizWQGHiHxL90Y0oX65xaY54315 rogid:ezli6d8R3mc5aNovKvPv2ayypbE9606 intact-crc:2411765E0AB50A5D|rigid:Hu4O80mmGgXQHT9fhJLzk9KpdFo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D2CFJ1 uniprotkb:Q15370 intact:EBI-6147949 intact:EBI-301238|ensembl:ENSP00000386652|uniprotkb:B7WPD3 psi-mi:d2cfj1_9flav(display_long) psi-mi:elob_human(display_long)|uniprotkb:ELOB(gene name)|psi-mi:ELOB(display_short)|uniprotkb:Elongin 18 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit B(gene name synonym)|uniprotkb:SIII p18(gene name synonym)|uniprotkb:TCEB2(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:54315(bvdv-2)|taxid:54315(Bovine viral diarrhea virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155083|imex:IM-17331-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR042542|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity) ensembl:ENSG00000103363(gene)|ensembl:ENST00000409906(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039049|mint:Q15370|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2JZ3|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:4WQO|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:6SIS|refseq:NP_009039.1|refseq:NP_996896.1|dip:DIP-29570N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:h4N69bizWQGHiHxL90Y0oX65xaY54315 rogid:apX4QFpDC4Dz3MAs7tQ8+XFHx6I9606 intact-crc:2411765E0AB50A5D|rigid:Hu4O80mmGgXQHT9fhJLzk9KpdFo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D2CFJ1 uniprotkb:P22492 intact:EBI-6147949 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 psi-mi:d2cfj1_9flav(display_long) psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:54315(bvdv-2)|taxid:54315(Bovine viral diarrhea virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155083|imex:IM-17331-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR042542|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:h4N69bizWQGHiHxL90Y0oX65xaY54315 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 intact-crc:2411765E0AB50A5D|rigid:Hu4O80mmGgXQHT9fhJLzk9KpdFo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D2CFJ1 uniprotkb:P12036 intact:EBI-6147949 intact:EBI-2880271|uniprotkb:Q9UQ14|uniprotkb:Q9UJS7|uniprotkb:Q96HF8|uniprotkb:B4DYY4|ensembl:ENSP00000311997 psi-mi:d2cfj1_9flav(display_long) psi-mi:nfh_human(display_long)|uniprotkb:NEFH(gene name)|psi-mi:NEFH(display_short)|uniprotkb:KIAA0845(gene name synonym)|uniprotkb:NFH(gene name synonym)|uniprotkb:200 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament triplet H protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:54315(bvdv-2)|taxid:54315(Bovine viral diarrhea virus 2) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155083|imex:IM-17331-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR042542|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity) refseq:NP_066554.2|ensembl:ENSG00000100285(gene)|ensembl:ENST00000310624(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005883"(neurofilament)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0061564"(axon development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR010790(Protein of unknown function DUF1388)|interpro:IPR018039|interpro:IPR033183|interpro:IPR039008|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:h4N69bizWQGHiHxL90Y0oX65xaY54315 rogid:TXMrn6SWBHIYQY1loZfVvMo9PtU9606 intact-crc:2411765E0AB50A5D|rigid:Hu4O80mmGgXQHT9fhJLzk9KpdFo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:Q02878 intact:EBI-6147978 intact:EBI-359655|uniprotkb:Q2M3Q3|uniprotkb:Q8WW97|ensembl:ENSP00000202773|ensembl:ENSP00000403172 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl6_human(display_long)|uniprotkb:RPL6(gene name)|psi-mi:RPL6(display_short)|uniprotkb:TXREB1(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 107(gene name synonym)|uniprotkb:Neoplasm-related protein C140(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_000961.2|refseq:NP_001019833.1|ensembl:ENSG00000089009(gene)|ensembl:ENST00000202773(transcript)|ensembl:ENST00000424576(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:Q02878|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001307066.1|refseq:NP_001307067.1|refseq:NP_001307068.1|refseq:NP_001307069.1|refseq:NP_001307070.1|refseq:XP_016875270.1|refseq:XP_016875271.1|dip:DIP-27547N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:Y7fx3ToInzucV2QmI8KLSdHxai09606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P18621 intact:EBI-6147978 intact:EBI-726937|uniprotkb:Q6NZ54|uniprotkb:Q7M4M5|uniprotkb:Q3KQW2|uniprotkb:B2R4H3|uniprotkb:B4E3C2|uniprotkb:B5ME31|uniprotkb:J3QL51|ensembl:ENSP00000462023|ensembl:ENSP00000462385|ensembl:ENSP00000463842|ensembl:ENSP00000480555|ensembl:ENSP00000482577 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl17_human(display_long)|uniprotkb:60S ribosomal protein L23(gene name synonym)|uniprotkb:PD-1(gene name synonym)|uniprotkb:RPL17(gene name)|psi-mi:RPL17(display_short)|uniprotkb:Large ribosomal subunit protein uL22(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_000976.1|refseq:NP_001030178.1|refseq:NP_001186269.1|refseq:NP_001186270.1|refseq:NP_001186271.1|refseq:NP_001186272.1|refseq:NP_001186273.1|refseq:NP_001186274.1|ensembl:ENSG00000265681(gene)|ensembl:ENST00000579248(transcript)|ensembl:ENST00000579408(transcript)|ensembl:ENST00000580261(transcript)|ensembl:ENST00000618613(transcript)|ensembl:ENST00000618619(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001063(Ribosomal protein L22/L17)|interpro:IPR005721(Ribosomal protein L22/L17, eukaryotic/archaeal)|interpro:IPR018260|interpro:IPR036394|mint:P18621|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:/i0W3WoeFakz+8R/YMYf2JQZytI9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P62899 intact:EBI-6147978 intact:EBI-1053664|intact:EBI-3867511|uniprotkb:B7Z4K2|uniprotkb:P12947|uniprotkb:Q53SQ5|uniprotkb:Q6LBJ6|uniprotkb:D3DVJ4|uniprotkb:Q6IRZ0|ensembl:ENSP00000264258|ensembl:ENSP00000386681 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl31_human(display_long)|uniprotkb:RPL31(gene name)|psi-mi:RPL31(display_short)|uniprotkb:Large ribosomal subunit protein eL31(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_000984.1|refseq:NP_001092047.1|refseq:NP_001093163.1|ensembl:ENSG00000071082(gene)|ensembl:ENST00000264258(transcript)|ensembl:ENST00000409733(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000054(Ribosomal protein L31e)|interpro:IPR020052|interpro:IPR023621|mint:P62899|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:77LFR7/2somk6blVogZf1XFdJLk9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P62910 intact:EBI-6147978 intact:EBI-438408|ensembl:ENSP00000380156|ensembl:ENSP00000380158|ensembl:ENSP00000388674|ensembl:ENSP00000416429|uniprotkb:P02433|uniprotkb:B2R4Q3 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl32_human(display_long)|uniprotkb:RPL32(gene name)|psi-mi:RPL32(display_short)|uniprotkb:Large ribosomal subunit protein eL32(gene name synonym)|uniprotkb:PP9932(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000144713(gene)|ensembl:ENST00000396953(transcript)|ensembl:ENST00000396957(transcript)|ensembl:ENST00000429711(transcript)|ensembl:ENST00000435983(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR001515(Ribosomal protein L32e)|interpro:IPR018263|interpro:IPR036351|mint:P62910|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000985.1|refseq:NP_001007074.1|refseq:NP_001007075.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:8Yhph2ETzWYd07yJcq1cVqsSRjo9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P62829 intact:EBI-6147978 intact:EBI-353303|uniprotkb:P23131|uniprotkb:Q3SWV7|uniprotkb:P24048|uniprotkb:Q29246|uniprotkb:Q6P5S1|ensembl:ENSP00000377865|ensembl:ENSP00000420311 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl23_human(display_long)|uniprotkb:RPL23(gene name)|psi-mi:RPL23(display_short)|uniprotkb:60S ribosomal protein L17(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|reactome:R-HSA-9010553|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|refseq:NP_000969.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000218(Ribosomal protein L14b/L23e)|interpro:IPR019972|interpro:IPR036853|mint:P62829|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|ensembl:ENSG00000125691(gene)|ensembl:ENST00000394332(transcript)|ensembl:ENST00000479035(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0005730"(nucleolus)|dip:DIP-33156N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:TiSVU2W4+lkwf12eb4+vG6IFlZA9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P62249 intact:EBI-6147978 intact:EBI-352480|uniprotkb:P17008|uniprotkb:B2RDD5|ensembl:ENSP00000251453 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs16_human(display_long)|uniprotkb:RPS16(gene name)|psi-mi:RPS16(display_short)|uniprotkb:Small ribosomal subunit protein uS9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001011.1|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000105193(gene)|ensembl:ENST00000251453(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097421"(liver regeneration)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR020574|mint:P62249|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|dip:DIP-33200N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:OrKriR6HsATLaO+drdUa2w3Gpd09606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:O43390 intact:EBI-6147978 intact:EBI-713419|uniprotkb:S4R3J4|uniprotkb:Q5TEH1|ensembl:ENSP00000304405|ensembl:ENSP00000363741|ensembl:ENSP00000489252|ensembl:ENSP00000489371|uniprotkb:Q9BV64|uniprotkb:Q2L7G6 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpr_human(display_long)|uniprotkb:HNRPR(gene name synonym)|uniprotkb:HNRNPR(gene name)|psi-mi:HNRNPR(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001095868.1|refseq:XP_005245768.1|ensembl:ENSG00000125944(gene)|ensembl:ENSG00000282958(gene)|ensembl:ENST00000302271(transcript)|ensembl:ENST00000374612(transcript)|ensembl:ENST00000634263(transcript)|ensembl:ENST00000634766(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043679"(axon terminus)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034411|interpro:IPR035979|mint:O43390|rcsb pdb:2DK2|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR041337|refseq:NP_005817.1|refseq:XP_011538773.1|refseq:NP_001284549.1|refseq:XP_016855497.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:UiOaRbnMd1S2FthR4RWltyq6xT49606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P49207 intact:EBI-6147978 intact:EBI-1051893|uniprotkb:Q6FG66|uniprotkb:Q9BUZ2|ensembl:ENSP00000378160|ensembl:ENSP00000378162|ensembl:ENSP00000378163|ensembl:ENSP00000423316|ensembl:ENSP00000423983 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl34_human(display_long)|uniprotkb:RPL34(gene name)|psi-mi:RPL34(display_short)|uniprotkb:Large ribosomal subunit protein eL34(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_000986.2|refseq:NP_296374.1|refseq:NP_001306161.1|refseq:NP_001306163.1|refseq:NP_001306164.1|refseq:NP_001306165.1|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|rcsb pdb:6Y6X|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR008195(Ribosomal protein L34e)|interpro:IPR018065|mint:P49207|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|ensembl:ENSG00000109475(gene)|ensembl:ENST00000394665(transcript)|ensembl:ENST00000394667(transcript)|ensembl:ENST00000394668(transcript)|ensembl:ENST00000502534(transcript)|ensembl:ENST00000506397(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:NSGnIE6uSimeraPQ7ZZ+xRugABg9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P18124 intact:EBI-6147978 intact:EBI-350806|uniprotkb:Q3KQU0|uniprotkb:Q15289|uniprotkb:Q5I0X1|uniprotkb:Q6IBM9|uniprotkb:A8K504|ensembl:ENSP00000339795 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl7_human(display_long)|uniprotkb:RPL7(gene name)|psi-mi:RPL7(display_short)|uniprotkb:Large ribosomal subunit protein uL30(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_000962.2|ensembl:ENSG00000147604(gene)|ensembl:ENST00000352983(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|mint:P18124|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72689 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:miVEaLOilDYcZXshxJlYbpnzwZ89606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:Q08211 intact:EBI-6147978 intact:EBI-352022|intact:EBI-1058470|uniprotkb:Q5VY62|uniprotkb:Q6PD69|uniprotkb:Q99556|uniprotkb:B2RNV4|uniprotkb:Q05CI5|uniprotkb:Q12803|uniprotkb:Q32Q22|ensembl:ENSP00000356520 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:dhx9_human(display_long)|uniprotkb:DHX9(gene name)|psi-mi:DHX9(display_short)|uniprotkb:DDX9(gene name synonym)|uniprotkb:NDH2(gene name synonym)|uniprotkb:DExH-box helicase 9(gene name synonym)|uniprotkb:RNA helicase A(gene name synonym)|uniprotkb:LKP(gene name synonym)|uniprotkb:Nuclear DNA helicase II(gene name synonym)|uniprotkb:DEAH box protein 9(gene name synonym)|uniprotkb:Leukophysin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001348.2|dip:DIP-31504N|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033679"(3'-5' DNA/RNA helicase activity)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045142"(triplex DNA binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0097165"(nuclear stress granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1905172"(RISC complex binding)|go:"GO:1905538"(polysome binding)|go:"GO:1905698"(positive regulation of polysome binding)|go:"GO:1990518"(single-stranded 3'-5' DNA helicase activity)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000765"(regulation of cytoplasmic translation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR044445|interpro:IPR044446|interpro:IPR044447|mint:Q08211|rcsb pdb:3LLM|rcsb pdb:3VYX|rcsb pdb:3VYY|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-72163|go:"GO:1904973"(positive regulation of viral translation)|ensembl:ENSG00000135829(gene)|ensembl:ENST00000367549(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006260"(DNA replication)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0016604"(nuclear body) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:b0VP2Frtvwa9WbYVMwB6TbV2uGU9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:Q9BTM1 intact:EBI-6147978 intact:EBI-4398590|uniprotkb:Q9NV63|ensembl:ENSP00000373730|ensembl:ENSP00000438553 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2aj_human(display_long)|uniprotkb:H2AJ(gene name)|psi-mi:H2AJ(display_short)|uniprotkb:H2AFJ(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_808760.1|ensembl:ENSG00000246705(gene)|ensembl:ENST00000389078(transcript)|ensembl:ENST00000544848(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:4EDU|rcsb pdb:6K60|rcsb pdb:6KVD|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-8939236 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:g6br63FeM17yJRfQI3GnmoM0vbc9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P61513 intact:EBI-6147978 intact:EBI-356793|uniprotkb:P12751|intact:EBI-1051378|uniprotkb:Q6FGF5|ensembl:ENSP00000418082 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl37a_human(display_long)|uniprotkb:RPL37A(gene name)|psi-mi:RPL37A(display_short)|uniprotkb:Large ribosomal subunit protein eL43(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_000989.1|ensembl:ENSG00000197756(gene)|ensembl:ENST00000491306(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002674(Ribosomal protein L37ae)|interpro:IPR011331(Ribosomal protein L37ae/L37e, core)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:P61513|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:0kwO2cVd99FGF2+5FyWo94C83049606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P62888 intact:EBI-6147978 intact:EBI-353116|uniprotkb:P04645|uniprotkb:Q502Z6|ensembl:ENSP00000287038|ensembl:ENSP00000428085|uniprotkb:B2R591 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl30_human(display_long)|uniprotkb:RPL30(gene name)|psi-mi:RPL30(display_short)|uniprotkb:Large ribosomal subunit protein eL30(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000156482(gene)|ensembl:ENST00000287038(transcript)|ensembl:ENST00000521291(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000231(Ribosomal protein L30e)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR022991|interpro:IPR029064|interpro:IPR039109|mint:P62888|rcsb pdb:3VI6|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000980.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:xR9LwYg6N7m9njT1pYumOPKZVu49606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:Q9UNX3 intact:EBI-6147978 intact:EBI-2949703|ensembl:ENSP00000265100|ensembl:ENSP00000428177|ensembl:ENSP00000428223|ensembl:ENSP00000430147|uniprotkb:B3KY82|uniprotkb:D3DQM0 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl26l_human(display_long)|uniprotkb:RPL26L1(gene name)|psi-mi:RPL26L1(display_short)|uniprotkb:RPL26P1(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL24-like 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000037241(gene)|ensembl:ENST00000265100(transcript)|ensembl:ENST00000519239(transcript)|ensembl:ENST00000519974(transcript)|ensembl:ENST00000521476(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005756(Ribosomal protein L26, eukaryotic/archaeal)|interpro:IPR005824(KOW)|interpro:IPR005825(Ribosomal protein L24/L26, conserved site)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041988|mint:Q9UNX3|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-2408557|refseq:NP_057177.1|refseq:XP_011532867.1|refseq:NP_001304909.1|refseq:NP_001304910.1|refseq:NP_001304911.1|refseq:XP_016865008.1|refseq:XP_016865009.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:dny/DWK4MvWD3FUJvW5+KGI3iJI9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P61313 intact:EBI-6147978 intact:EBI-443462|ensembl:ENSP00000309334|ensembl:ENSP00000346867|ensembl:ENSP00000388529|ensembl:ENSP00000416692|ensembl:ENSP00000483260|ensembl:ENSP00000493759|uniprotkb:Q642I1|uniprotkb:Q9H2E5|uniprotkb:P39030|uniprotkb:P41051|uniprotkb:Q6IPX6|uniprotkb:Q8WYP2|uniprotkb:Q96C44|uniprotkb:Q5U0C0|intact:EBI-2877712 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl15_human(display_long)|uniprotkb:RPL15(gene name)|psi-mi:RPL15(display_short)|uniprotkb:EC45(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL15(gene name synonym)|uniprotkb:TCBAP0781(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000174748(gene)|ensembl:ENST00000307839(transcript)|ensembl:ENST00000354811(transcript)|ensembl:ENST00000413699(transcript)|ensembl:ENST00000415719(transcript)|ensembl:ENST00000611050(transcript)|ensembl:ENST00000644185(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|interpro:IPR000439(Ribosomal protein L15e)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR020925|interpro:IPR024794|mint:P61313|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_002939.2|refseq:NP_001240308.1|refseq:NP_001240309.1|refseq:NP_001240311.1|refseq:NP_001240312.1|refseq:NP_001240313.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:wllGpJicgC5uwkZV6e4QRwDcrBo9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:Q6FI13 intact:EBI-6147978 intact:EBI-353620|uniprotkb:P20670|uniprotkb:B2R5F0|ensembl:ENSP00000358155|ensembl:ENSP00000475814 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a2a_human(display_long)|uniprotkb:H2AC18(gene name)|psi-mi:H2AC18(display_short)|uniprotkb:H2AC19(gene name)|psi-mi:H2AC19(display_short)|uniprotkb:H2A-clustered histone 18(gene name synonym)|uniprotkb:H2A-clustered histone 19(gene name synonym)|uniprotkb:H2AFO(gene name synonym)|uniprotkb:HIST2H2AA(gene name synonym)|uniprotkb:HIST2H2AA3(gene name synonym)|uniprotkb:HIST2H2AA4(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/o(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001035807.1|refseq:NP_003507.1|ensembl:ENSG00000203812(gene)|ensembl:ENSG00000272196(gene)|ensembl:ENST00000369159(transcript)|ensembl:ENST00000607355(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6Y5D|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|dip:DIP-33167N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:PMuIm2XMN5q4wk+wYJ94mmnCe4w9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:Q9UI10 intact:EBI-6147978 intact:EBI-2340132|uniprotkb:Q53RY7|uniprotkb:Q9UIQ9|uniprotkb:Q9UJ95|uniprotkb:Q5BJF4|uniprotkb:Q9UBG4|uniprotkb:Q9BUV9|ensembl:ENSP00000233552 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ei2bd_human(display_long)|uniprotkb:EIF2B4(gene name)|psi-mi:EIF2B4(display_short)|uniprotkb:EIF2BD(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit delta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001029288.1|refseq:NP_056451.3|refseq:NP_751945.2|refseq:NP_001305894.1|refseq:NP_001305895.1|refseq:NP_001305896.1|refseq:NP_001305897.1|ensembl:ENSG00000115211(gene)|ensembl:ENST00000347454(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006417"(regulation of translation)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0042552"(myelination)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042529|mint:Q9UI10|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:ZCU4mIO5zkmBajIvBRe3b2PZINw9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P46779 intact:EBI-6147978 intact:EBI-366357|uniprotkb:Q6IAY0|uniprotkb:Q96FX1|uniprotkb:Q9BWQ0|uniprotkb:B2R4A6|uniprotkb:B4DEP9|uniprotkb:E9PB24|uniprotkb:C9JB50|uniprotkb:G5E9L2|ensembl:ENSP00000342787|ensembl:ENSP00000453319 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl28_human(display_long)|uniprotkb:RPL28(gene name)|psi-mi:RPL28(display_short)|uniprotkb:Large ribosomal subunit protein eL28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001129608.1|refseq:NP_001129609.1|refseq:NP_000982.2|refseq:NP_001129606.1|refseq:NP_001129607.1|ensembl:ENSG00000108107(gene)|ensembl:ENST00000344063(transcript)|ensembl:ENST00000559463(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002672(Ribosomal protein L28e)|interpro:IPR029004|mint:P46779|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:I7Me1zjfxk98g6C2NoYOWlmrYVc9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:Q12905 intact:EBI-6147978 intact:EBI-357925|uniprotkb:A6NDB0|uniprotkb:Q5SR10|uniprotkb:Q5SR11|uniprotkb:Q7L7R3|uniprotkb:Q9BWD4|uniprotkb:Q9P1N0|uniprotkb:B2R8G7|ensembl:ENSP00000355011 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ilf2_human(display_long)|uniprotkb:PRO3063(orf name)|uniprotkb:NF45(gene name synonym)|uniprotkb:ILF2(gene name)|psi-mi:ILF2(display_short)|uniprotkb:Nuclear factor of activated T-cells 45 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_004506.2|refseq:NP_001254738.1|ensembl:ENSG00000143621(gene)|ensembl:ENST00000361891(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR043519|mint:Q12905|reactome:R-HSA-6798695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:HwUDuY6Ev7csoTThxZCW8nJT88o9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:Q8NC51 intact:EBI-6147978 intact:EBI-523558|uniprotkb:Q8WUH0|uniprotkb:Q96SE2|uniprotkb:Q9BTY3|uniprotkb:Q9BUM4|uniprotkb:Q9Y367|uniprotkb:Q9Y4S3|uniprotkb:Q5VU19|intact:EBI-1058614|ensembl:ENSP00000360034|uniprotkb:Q5VU20|uniprotkb:Q5VU22 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pairb_human(display_long)|uniprotkb:PAI1 RNA-binding protein 1(gene name synonym)|uniprotkb:SERPINE1 mRNA-binding protein 1(gene name synonym)|uniprotkb:CGI-55(orf name)|uniprotkb:SERBP1(gene name)|psi-mi:SERBP1(display_short)|uniprotkb:PAIRBP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000142864(gene)|ensembl:ENST00000370995(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030578"(PML body organization)|go:"GO:0032183"(SUMO binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043022"(ribosome binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006861(Hyaluronan/mRNA binding protein)|interpro:IPR027205|interpro:IPR032381|interpro:IPR039764|mint:Q8NC51|rcsb pdb:4V6X|rcsb pdb:6Z6M|rcsb pdb:6Z6N|refseq:NP_001018077.1|refseq:NP_001018078.1|refseq:NP_001018079.1|refseq:NP_056455.3|dip:DIP-33819N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:lVkIPRkoXs3B4Qop1pA2zG/RKlo9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P50914 intact:EBI-6147978 intact:EBI-356746|uniprotkb:Q45RF0|uniprotkb:Q53G20|uniprotkb:Q8TBD5|uniprotkb:Q8WUT0|uniprotkb:Q92579|uniprotkb:Q96GR0|uniprotkb:Q9BSB8|uniprotkb:Q9BW65|uniprotkb:Q9BYF6|ensembl:ENSP00000345156|ensembl:ENSP00000379506 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl14_human(display_long)|uniprotkb:RPL14(gene name)|psi-mi:RPL14(display_short)|uniprotkb:CAG-ISL 7(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001030168.1|refseq:NP_003964.3|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002784(Ribosomal protein L14)|interpro:IPR008991(Translation protein SH3-like)|ensembl:ENSG00000188846(gene)|ensembl:ENST00000338970(transcript)|ensembl:ENST00000396203(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041985|mint:P50914|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|interpro:IPR039660|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y2L - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:AjaguD5hgHtcBbJq5QfuG6XdTcE9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:O75569 intact:EBI-6147978 intact:EBI-713955|ensembl:ENSP00000318176|uniprotkb:Q53G24|uniprotkb:Q6X7T5|uniprotkb:Q8NDK4|uniprotkb:A8K3I6 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:prkra_human(display_long)|uniprotkb:Protein activator of the interferon-induced protein kinase(gene name synonym)|uniprotkb:PKR-associated protein X(gene name synonym)|uniprotkb:PKR-associating protein X(gene name synonym)|uniprotkb:HSD-14(orf name)|uniprotkb:PRKRA(gene name)|psi-mi:PRKRA(display_short)|uniprotkb:RAX(gene name synonym)|uniprotkb:PACT(gene name synonym)|uniprotkb:HSD14(orf name)|uniprotkb:Protein kinase, interferon-inducible double-stranded RNA-dependent activator(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006955"(immune response)|go:"GO:0008047"(enzyme activator activity)|ensembl:ENSG00000180228(gene)|ensembl:ENST00000325748(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR033363|interpro:IPR044465|interpro:IPR044466|interpro:IPR044467|mint:O75569|rcsb pdb:2DIX|reactome:R-HSA-203927|reactome:R-HSA-426486|refseq:NP_001132989.1|refseq:NP_001132990.1|refseq:NP_003681.1|dip:DIP-41809N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:tZfziopZlC+1d3De97G3kDY+Tog9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P38159 intact:EBI-6147978 intact:EBI-743526|ensembl:ENSP00000359645|uniprotkb:Q5JQ67|uniprotkb:Q969R3|uniprotkb:D3DWH0|uniprotkb:E9PG86|uniprotkb:Q8N8Y7|uniprotkb:B4E3U4 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rbmx_human(display_long)|uniprotkb:Glycoprotein p43(gene name synonym)|uniprotkb:RBMX(gene name)|psi-mi:RBMX(display_short)|uniprotkb:HNRPG(gene name synonym)|uniprotkb:RBMXP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000147274(gene)|ensembl:ENST00000320676(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P38159|rcsb pdb:2MB0|rcsb pdb:2MKS|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_002130.2|refseq:NP_001158275.1|dip:DIP-34447N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:ocCkdy9PxjeVLUQf0tMVCEhFfO89606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:O95793 intact:EBI-6147978 intact:EBI-358174|uniprotkb:Q6GTM4|uniprotkb:Q9H5B5|intact:EBI-366174|uniprotkb:Q9H5B4|uniprotkb:Q9Y3Q2|uniprotkb:A8K9Z4|ensembl:ENSP00000360922|uniprotkb:E1P5Y1|uniprotkb:E1P608|uniprotkb:Q5JW29 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:stau1_human(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001309856.1|refseq:NP_001309858.1|refseq:NP_001309859.1|refseq:NP_001032405.1|refseq:NP_004593.2|refseq:NP_059346.2|refseq:NP_059347.2|refseq:NP_059348.2|refseq:NP_001306063.1|refseq:NP_001306064.1|ensembl:ENSG00000124214(gene)|ensembl:ENST00000371856(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|refseq:XP_005260584.1|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:O95793|rcsb pdb:4DKK|rcsb pdb:6HTU|rcsb pdb:6SDW|rcsb pdb:6SDY - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:uYjbWja/hG5M/3likHLe00Z2FgY9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:Q7L7L0 intact:EBI-6147978 intact:EBI-5325551|ensembl:ENSP00000355656|ensembl:ENSP00000493926|uniprotkb:B2R4S4 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a3_human(display_long)|uniprotkb:H2AW(gene name)|psi-mi:H2AW(display_short)|uniprotkb:HIST3H2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000181218(gene)|ensembl:ENSG00000284841(gene)|ensembl:ENST00000366695(transcript)|refseq:NP_254280.1|ensembl:ENST00000645741(transcript)|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-5689603|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q7L7L0|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000786"(nucleosome)|dip:DIP-48936N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:t0RdR1SmUtmwRjtCS3uTyLGqSUI9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P62847 intact:EBI-6147978 intact:EBI-354515|uniprotkb:P16632|uniprotkb:Q7Z3D1|uniprotkb:Q5T0P7|uniprotkb:Q5T0P8|uniprotkb:E7EPK6|ensembl:ENSP00000478869 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs24_human(display_long)|uniprotkb:RPS24(gene name)|psi-mi:RPS24(display_short)|uniprotkb:Small ribosomal subunit protein eS24(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001135757.1|refseq:NP_001017.1|refseq:NP_001135755.1|refseq:NP_148982.1|ensembl:ENSG00000138326(gene)|ensembl:ENST00000613865(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR001976(Ribosomal protein S24e)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR018098|mint:P62847|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6XA1|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:M/qkRxabHx9PFaOM7EwKDOOwu7Q9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P0C0S8 intact:EBI-6147978 intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:Q07020 intact:EBI-6147978 intact:EBI-352694|intact:EBI-8456577|intact:MINT-8429255|uniprotkb:F8VWC5|uniprotkb:Q8WTZ6|ensembl:ENSP00000447001 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl18_human(display_long)|uniprotkb:RPL18(gene name)|psi-mi:RPL18(display_short)|uniprotkb:Large ribosomal subunit protein eL18(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_000970.1|ensembl:ENSG00000063177(gene)|ensembl:ENST00000549920(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR000039(Ribosomal protein L18e)|interpro:IPR021131|interpro:IPR021132|interpro:IPR036227|mint:Q07020|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001257419.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:GgzBcLEQgBqbApFlaQIU2jktkAE9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P42766 intact:EBI-6147978 intact:EBI-356819|uniprotkb:Q4VBY5|uniprotkb:Q9BYF4|uniprotkb:Q5JTN5|uniprotkb:Q6IBC7|uniprotkb:Q96QJ7|uniprotkb:A8K4V7|ensembl:ENSP00000259469 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl35_human(display_long)|uniprotkb:RPL35(gene name)|psi-mi:RPL35(display_short)|uniprotkb:Large ribosomal subunit protein uL29(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_009140.1|ensembl:ENSG00000136942(gene)|ensembl:ENST00000348462(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001854(Ribosomal protein L29)|interpro:IPR018254|interpro:IPR036049|mint:P42766|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:jhzt7gCff2vdUb1Ff/VTBF698Pg9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P84098 intact:EBI-6147978 intact:EBI-916524|uniprotkb:P14118|uniprotkb:P22908|uniprotkb:Q502Y6|uniprotkb:Q7Z6E4|uniprotkb:B2R4K2|ensembl:ENSP00000225430 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl19_human(display_long)|uniprotkb:RPL19(gene name)|psi-mi:RPL19(display_short)|uniprotkb:Large ribosomal subunit protein eL19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_000972.1|ensembl:ENSG00000108298(gene)|ensembl:ENST00000225430(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0097421"(liver regeneration)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR000196(Ribosomal protein L19/L19e)|interpro:IPR015972(Ribosomal protein L19/L19e, domain 1)|interpro:IPR023638|interpro:IPR033935|interpro:IPR035970|interpro:IPR039547|mint:P84098|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:sYEwdB8ySbxh3iL0uqlfRRVFiWw9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P34931 intact:EBI-6147978 intact:EBI-354912|uniprotkb:O75634|uniprotkb:Q2HXR3|uniprotkb:Q8NE72|uniprotkb:A6NNB0|uniprotkb:Q96QC9|uniprotkb:Q9UQM1|uniprotkb:B0UXW8|ensembl:ENSP00000364805|ensembl:ENSP00000372881|ensembl:ENSP00000396486|ensembl:ENSP00000408347 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hs71l_human(display_long)|uniprotkb:HSPA1L(gene name)|psi-mi:HSPA1L(display_short)|uniprotkb:Heat shock 70 kDa protein 1-Hom(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_005518.3|ensembl:ENSG00000204390(gene)|ensembl:ENSG00000206383(gene)|ensembl:ENSG00000234258(gene)|ensembl:ENSG00000236251(gene)|ensembl:ENST00000375654(transcript)|ensembl:ENST00000383390(transcript)|ensembl:ENST00000417601(transcript)|ensembl:ENST00000456772(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0072562"(blood microparticle)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P34931|rcsb pdb:3GDQ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:KS02DcMpD2sxSF36hUjKiSdYi4c9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P62854 intact:EBI-6147978 intact:EBI-353438|uniprotkb:P02383|uniprotkb:Q3MHD8|uniprotkb:P70394|uniprotkb:Q06722|uniprotkb:Q6IRY4|ensembl:ENSP00000348849|ensembl:ENSP00000450339|ensembl:ENSP00000496643 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs26_human(display_long)|uniprotkb:RPS26(gene name)|psi-mi:RPS26(display_short)|uniprotkb:Small ribosomal subunit protein eS26(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001020.2|refseq:XP_005276741.1|rcsb pdb:6OLG|rcsb pdb:6OLF|ensembl:ENST00000356464(transcript)|ensembl:ENST00000552361(transcript)|ensembl:ENST00000646449(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000892(Ribosomal protein S26e)|interpro:IPR038551|mint:P62854|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6G5H|ensembl:ENSG00000197728(gene)|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-156827 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:bo2ruYMNjjLCMo/kwAWzmlJrrjU9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P62280 intact:EBI-6147978 intact:EBI-1047710|uniprotkb:B2R4F5|uniprotkb:P04643|uniprotkb:Q498Y6|uniprotkb:Q6IRY0|ensembl:ENSP00000270625 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs11_human(display_long)|uniprotkb:RPS11(gene name)|psi-mi:RPS11(display_short)|uniprotkb:Small ribosomal subunit protein uS17(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001006.1|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000266(Ribosomal protein S17)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019979|interpro:IPR028333|interpro:IPR032440|mint:P62280|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|go:"GO:0005840"(ribosome)|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|ensembl:ENSG00000142534(gene)|ensembl:ENST00000270625(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6OM0|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:0fqJjtWAuz31VTKt2mbteRoi8vA9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:Q16777 intact:EBI-6147978 intact:EBI-5325566|ensembl:ENSP00000332194|uniprotkb:Q6DRA7|uniprotkb:Q8IUE5 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a2c_human(display_long)|uniprotkb:H2AC20(gene name)|psi-mi:H2AC20(display_short)|uniprotkb:H2A-clustered histone 20(gene name synonym)|uniprotkb:H2AFQ(gene name synonym)|uniprotkb:HIST2H2AC(gene name synonym)|uniprotkb:Histone H2A-GL101(gene name synonym)|uniprotkb:Histone H2A/q(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-5689603|ensembl:ENSG00000184260(gene)|ensembl:ENST00000331380(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q16777|rcsb pdb:6Y5E|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|refseq:NP_003508.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:Wejrpp9wK3GvA4ahJDVyEH+cwlQ9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P62424 intact:EBI-6147978 intact:EBI-354172|uniprotkb:P11518|uniprotkb:Q5T8U4|ensembl:ENSP00000361076|ensembl:ENSP00000487443 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl7a_human(display_long)|uniprotkb:RPL7A(gene name)|psi-mi:RPL7A(display_short)|uniprotkb:SURF-3(gene name synonym)|uniprotkb:SURF3(gene name synonym)|uniprotkb:Surfeit locus protein 3(gene name synonym)|uniprotkb:PLA-X polypeptide(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_000963.1|dip:DIP-31502N|ensembl:ENSG00000148303(gene)|ensembl:ENSG00000280858(gene)|ensembl:ENST00000323345(transcript)|ensembl:ENST00000630979(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR001921(Ribosomal protein L7A)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:P62424|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|go:"GO:0005634"(nucleus)|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:shPtLmc+oabT/rSwho+tP1iJy4k9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:Q99714 intact:EBI-6147978 intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P39023 intact:EBI-6147978 intact:EBI-1056348|uniprotkb:Q15548|uniprotkb:Q5I0G0|uniprotkb:B2RDV9|ensembl:ENSP00000346001 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl3_human(display_long)|uniprotkb:RPL3(gene name)|psi-mi:RPL3(display_short)|uniprotkb:HIV-1 TAR RNA-binding protein B(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL3(gene name synonym)|uniprotkb:OK/SW-cl.32(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_000958.1|ensembl:ENSG00000100316(gene)|ensembl:ENST00000216146(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|mint:P39023|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:j3MVAYfO/bziJBPmH4zCFqFskZ89606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P20671 intact:EBI-6147978 intact:EBI-4407441|uniprotkb:A0PK91|uniprotkb:P57754|uniprotkb:Q6FGY6|ensembl:ENSP00000341094 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a1d_human(display_long)|uniprotkb:H2AC7(gene name)|psi-mi:H2AC7(display_short)|uniprotkb:H2AFG(gene name synonym)|uniprotkb:HIST1H2AD(gene name synonym)|uniprotkb:Histone H2A.3(gene name synonym)|uniprotkb:Histone H2A/g(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_066409.1|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000196866(gene)|ensembl:ENST00000341023(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:5GT3|rcsb pdb:6KBB|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:Geraq+dGw3pvAAhgzzXQnYxDOOw9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P67809 intact:EBI-6147978 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P46776 intact:EBI-6147978 intact:EBI-350581|uniprotkb:B2R4B3|ensembl:ENSP00000346015 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl27a_human(display_long)|uniprotkb:RPL27A(gene name)|psi-mi:RPL27A(display_short)|uniprotkb:Large ribosomal subunit protein uL15(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_000981.1|ensembl:ENSG00000166441(gene)|ensembl:ENST00000314138(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001196(Ribosomal protein L15)|interpro:IPR021131|interpro:IPR027386|interpro:IPR030878|interpro:IPR036227|mint:P46776|rcsb pdb:4BXF|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72706|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6IP6|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6OM7|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:6IP5|dip:DIP-33121N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:tUezMQBw+SWmLYq8M0pkLCF8vO89606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P05388 intact:EBI-6147978 intact:EBI-354101|uniprotkb:Q9BVK4|intact:EBI-8012155|intact:MINT-8395053|uniprotkb:Q3B7A4|ensembl:ENSP00000339027|ensembl:ENSP00000376299|ensembl:ENSP00000449328 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rla0_human(display_long)|uniprotkb:RPLP0(gene name)|psi-mi:RPLP0(display_short)|uniprotkb:60S ribosomal protein L10E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL10(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_000993.1|refseq:NP_444505.1|ensembl:ENSG00000089157(gene)|ensembl:ENST00000228306(transcript)|ensembl:ENST00000392514(transcript)|ensembl:ENST00000551150(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0098794"(postsynapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR030670|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:P05388|rcsb pdb:4V6W|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8950505|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:xv3QHqnXxvCd3BOIeHVkqEnSNNk9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P08865 intact:EBI-6147978 intact:EBI-354112|uniprotkb:Q6NSD1|uniprotkb:Q6NXQ8|uniprotkb:Q86VC0|uniprotkb:P11085|uniprotkb:P12030|uniprotkb:Q16471|uniprotkb:Q6IPD1|uniprotkb:Q6IPD2|ensembl:ENSP00000346067 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rssa_human(display_long)|uniprotkb:RPSA(gene name)|psi-mi:RPSA(display_short)|uniprotkb:LAMBR(gene name synonym)|uniprotkb:LAMR1(gene name synonym)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:Colon carcinoma laminin-binding protein(gene name synonym)|uniprotkb:NEM/1CHD4(gene name synonym)|uniprotkb:Multidrug resistance-associated protein MGr1-Ag(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_002286.2|refseq:NP_001291217.1|dip:DIP-32878N|ensembl:ENSG00000168028(gene)|ensembl:ENST00000301821(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0007155"(cell adhesion)|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZOJ|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|go:"GO:0043236"(laminin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P08865|rcsb pdb:3BCH|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:Jpv3I3G5C297fHfNwIqyB9Pf8/A9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:Q92522 intact:EBI-6147978 intact:EBI-876335|ensembl:ENSP00000329662 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h1x_human(display_long)|uniprotkb:H1-10(gene name)|psi-mi:H1-10(display_short)|uniprotkb:H1FX(gene name synonym)|uniprotkb:Histone H1x(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000184897(gene)|ensembl:ENST00000333762(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045296"(cadherin binding)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q92522|refseq:NP_006017.1|dip:DIP-36358N|rcsb pdb:2LSO|rcsb pdb:6L9Z|rcsb pdb:7K60|rcsb pdb:7K63 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:T+NweCoHXj0rYsS6gJ4V42R9MpA9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:Q12906 intact:EBI-6147978 intact:EBI-78756|uniprotkb:A8K6F2|uniprotkb:O43409|uniprotkb:Q6P1X1|uniprotkb:Q86XY7|uniprotkb:Q99544|uniprotkb:Q99545|uniprotkb:Q9BZH4|uniprotkb:Q9BZH5|uniprotkb:Q9NQ95|uniprotkb:Q9NQ96|uniprotkb:Q9NQ97|uniprotkb:Q9NQ98|uniprotkb:Q9NQ99|uniprotkb:Q9NQA0|uniprotkb:Q9NQA1|uniprotkb:Q9NQA2|uniprotkb:Q9NRN2|uniprotkb:Q9NRN3|uniprotkb:Q9NRN4|uniprotkb:Q9UMZ9|uniprotkb:Q9UN00|uniprotkb:Q9UN84|uniprotkb:Q9UNA2|ensembl:ENSP00000468156|intact:EBI-10970055|uniprotkb:G5E9M5 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ilf3_human(display_long)|uniprotkb:ILF3(gene name)|psi-mi:ILF3(display_short)|uniprotkb:MPHOSPH4(gene name synonym)|uniprotkb:NF90(gene name synonym)|uniprotkb:Nuclear factor of activated T-cells 90 kDa(gene name synonym)|uniprotkb:Double-stranded RNA-binding protein 76(gene name synonym)|uniprotkb:Translational control protein 80(gene name synonym)|uniprotkb:Nuclear factor associated with dsRNA(gene name synonym)|uniprotkb:M-phase phosphoprotein 4(gene name synonym)|uniprotkb:DRBF(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000129351(gene)|ensembl:ENST00000590261(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051607"(defense response to virus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR033099|interpro:IPR043519|mint:Q12906|rcsb pdb:2L33|rcsb pdb:3P1X|refseq:NP_001131145.1|refseq:NP_004507.2|refseq:NP_036350.2|refseq:NP_060090.2|refseq:NP_703194.1|refseq:XP_016882252.1|refseq:XP_011526286.2|dip:DIP-29853N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:iri+WBUtektANRSCpBO1XBCd9Wk9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P07910 intact:EBI-6147978 intact:EBI-357966|uniprotkb:P22628|uniprotkb:Q53EX2|uniprotkb:Q59FD3|uniprotkb:Q5FWE8|uniprotkb:Q86SF8|uniprotkb:Q86U45|uniprotkb:Q96HK7|uniprotkb:Q96HM4|uniprotkb:Q96IY5|uniprotkb:Q9BTS3|uniprotkb:D3DS19|uniprotkb:D3DS22|intact:EBI-28976506|ensembl:ENSP00000404848|ensembl:ENSP00000451291|ensembl:ENSP00000452276 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpc_human(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001070910.1|refseq:NP_001070911.1|refseq:NP_004491.2|refseq:NP_112604.2|ensembl:ENSP00000404848|ensembl:ENST00000430246|ensembl:ENSP00000442816|ensembl:ENST00000553300|ensembl:ENSP00000450544|ensembl:ENSP00000451291|ensembl:ENST00000554969|ensembl:ENSP00000452276|ensembl:ENSP00000450725|ensembl:ENST00000555883|ensembl:ENSP00000450629|ensembl:ENST00000556628|ensembl:ENSP00000451652|ensembl:ENST00000556897|ensembl:ENSP00000451176|refseq:XP_011535010.1|refseq:XP_011535011.1|refseq:XP_011535012.1|refseq:XP_011535013.1|refseq:XP_011535014.1|refseq:XP_016876741.1|refseq:XP_016876742.1|dip:DIP-29854N|refseq:XP_006720188.1|ensembl:ENSG00000092199(gene)|ensembl:ENST00000420743(transcript)|ensembl:ENST00000554455(transcript)|ensembl:ENST00000557201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979|mint:P07910|rcsb pdb:1TXP|rcsb pdb:1WF2|rcsb pdb:2MXY|rcsb pdb:2MZ1|rcsb pdb:3LN4|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:Fj5tiH0wrNUjTnsURIg8dB8laMg9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P39019 intact:EBI-6147978 intact:EBI-354451|ensembl:ENSP00000469228|ensembl:ENSP00000470004|ensembl:ENSP00000470972 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs19_human(display_long)|uniprotkb:RPS19(gene name)|psi-mi:RPS19(display_short)|uniprotkb:Small ribosomal subunit protein eS19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001013.1|ensembl:ENSG00000105372(gene)|ensembl:ENST00000593863(transcript)|ensembl:ENST00000598742(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003723"(RNA binding)|ensembl:ENST00000600467(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0007000"(nucleolus organization)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060265"(positive regulation of respiratory burst involved in inflammatory response)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001266(Ribosomal protein S19e)|interpro:IPR018277|interpro:IPR036388|interpro:IPR036390|mint:P39019|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001308412.1|refseq:NP_001308413.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:3YqdJJJG+2nqoBf3PLu1fs7pVkY9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P62750 intact:EBI-6147978 intact:EBI-353254|uniprotkb:P29316|uniprotkb:Q92774|uniprotkb:P39024|uniprotkb:B2R5B2|ensembl:ENSP00000389103 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl23a_human(display_long)|uniprotkb:RPL23A(gene name)|psi-mi:RPL23A(display_short)|uniprotkb:Large ribosomal subunit protein uL23(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|refseq:NP_000975.2|ensembl:ENSG00000198242(gene)|ensembl:ENST00000422514(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904841"(TORC2 complex binding)|interpro:IPR001014(Ribosomal protein L23, conserved site)|interpro:IPR005633(Ribosomal protein L23/L25, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|interpro:IPR019985|mint:P62750|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:lA1ubRFO9/Tl54Z1dKUzoCKvpAo9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P83881 intact:EBI-6147978 intact:EBI-1054835|uniprotkb:P09896|uniprotkb:P10661|uniprotkb:Q5J9I6|uniprotkb:Q08ES5|ensembl:ENSP00000446503 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl36a_human(display_long)|uniprotkb:60S ribosomal protein L44(gene name synonym)|uniprotkb:Cell migration-inducing gene 6 protein(gene name synonym)|uniprotkb:RPL36A(gene name)|psi-mi:RPL36A(display_short)|uniprotkb:MIG6(orf name)|uniprotkb:RPL44(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 15 protein(gene name synonym)|uniprotkb:GIG15(orf name)|uniprotkb:Large ribosomal subunit protein eL42(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_066357.2|ensembl:ENSG00000241343(gene)|ensembl:ENST00000553110(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR000552(Ribosomal protein L44e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:P83881|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:OrRyOEVJZbSdttK93KL/DS5YxJ89606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:Q93077 intact:EBI-6147978 intact:EBI-725259|uniprotkb:O00775|uniprotkb:O00776|uniprotkb:O00777|uniprotkb:O00778|uniprotkb:Q540R1|uniprotkb:B2R4F7|ensembl:ENSP00000321389|ensembl:ENSP00000367022|ensembl:ENSP00000473534 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a1c_human(display_long)|uniprotkb:H2AC6(gene name)|psi-mi:H2AC6(display_short)|uniprotkb:H2A-clustered histone 6(gene name synonym)|uniprotkb:H2AFL(gene name synonym)|uniprotkb:HIST1H2AC(gene name synonym)|uniprotkb:Histone H2A/l(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_003503.1|ensembl:ENSG00000180573(gene)|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENST00000314088(transcript)|ensembl:ENST00000377791(transcript)|ensembl:ENST00000602637(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|rcsb pdb:6C0W|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:7A08|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|interpro:IPR032458 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:m00IdooZksbNGKHSsaVvGFVpcko9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P63220 intact:EBI-6147978 intact:EBI-714051|uniprotkb:P35265|ensembl:ENSP00000345957 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs21_human(display_long)|uniprotkb:RPS21(gene name)|psi-mi:RPS21(display_short)|uniprotkb:Small ribosomal subunit protein eS21(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000171858(gene)|ensembl:ENST00000343986(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000461"("endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001015.1|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR001931(Ribosomal protein S21e)|interpro:IPR018279|interpro:IPR038579|mint:P63220|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6ZMO|rcsb pdb:6G5H|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6G5I|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:7K5I|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:3gi91+fAL7ogzcoJlVEaN4D+87A9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P62917 intact:EBI-6147978 intact:EBI-438527|ensembl:ENSP00000262584|ensembl:ENSP00000378378|ensembl:ENSP00000433464|uniprotkb:P25120|uniprotkb:Q567Q7|uniprotkb:Q969V7|uniprotkb:Q9BWQ9|uniprotkb:A8K094|uniprotkb:D3DWN2 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl8_human(display_long)|uniprotkb:RPL8(gene name)|psi-mi:RPL8(display_short)|uniprotkb:Large ribosomal subunit protein uL2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) rcsb pdb:4CCN|rcsb pdb:4CCO|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4Y3O|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000161016(gene)|ensembl:ENST00000262584(transcript)|ensembl:ENST00000394920(transcript)|ensembl:ENST00000528957(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098794"(postsynapse)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR022666|interpro:IPR022669|interpro:IPR022671|interpro:IPR023672|mint:P62917|rcsb pdb:4CCM|refseq:NP_000964.1|refseq:NP_150644.1|refseq:NP_001304700.1|refseq:NP_001304711.1|dip:DIP-37967N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:+b/ORzdCy/nqFLsKRV9VhIZgdjg9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P16989 intact:EBI-6147978 intact:EBI-358193|uniprotkb:Q14121|uniprotkb:Q969N6|uniprotkb:Q96B76|uniprotkb:B2RBW6|intact:EBI-2560381|ensembl:ENSP00000228251 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ybox3_human(display_long)|uniprotkb:YBX3(gene name)|psi-mi:YBX3(display_short)|uniprotkb:CSDA(gene name synonym)|uniprotkb:Cold shock domain-containing protein A(gene name synonym)|uniprotkb:DBPA(gene name synonym)|uniprotkb:DNA-binding protein A(gene name synonym)|uniprotkb:Single-strand DNA-binding protein NF-GMB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) go:"GO:0046622"(positive regulation of organ growth)|refseq:NP_001138898.1|refseq:NP_003642.3|dip:DIP-42489N|ensembl:ENSG00000060138(gene)|ensembl:ENST00000228251(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008584"(male gonad development)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031267"(small GTPase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:1902219"(negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1905538"(polysome binding)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P16989 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:cWuhmwOBWe5HdgPG1gyN7KzN4Rs9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P62861 intact:EBI-6147978 intact:EBI-358093|uniprotkb:Q05472|uniprotkb:Q95261|uniprotkb:Q9H5V4|ensembl:ENSP00000431822|ensembl:ENSP00000434440|ensembl:ENSP00000435370 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs30_human(display_long)|uniprotkb:FAU(gene name)|psi-mi:FAU(display_short)|uniprotkb:Small ribosomal subunit protein eS30(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000149806(gene)|ensembl:ENST00000527548(transcript)|ensembl:ENST00000529639(transcript)|ensembl:ENST00000531743(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR006846(Ribosomal protein S30)|mint:P62861|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:mfW+tko85h9ZOK7wNXUsYiYY3Hc9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P83731 intact:EBI-6147978 intact:EBI-353146|ensembl:ENSP00000377640|uniprotkb:P38663|uniprotkb:Q6IBS3|uniprotkb:B2R4Y3 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl24_human(display_long)|uniprotkb:RPL24(gene name)|psi-mi:RPL24(display_short)|uniprotkb:60S ribosomal protein L30(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL24(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) go:"GO:0016020"(membrane)|go:"GO:0021554"(optic nerve development)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR000988(Ribosomal protein L24e)|interpro:IPR011017(TRASH)|interpro:IPR023442|interpro:IPR038630|mint:P83731|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZMI|rcsb pdb:6ZME|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000114391(gene)|ensembl:ENST00000394077(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0010458"(exit from mitosis)|refseq:NP_000977.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:+Ah+YGgcjqOsk5ZS1HZUMQA/Of89606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P63173 intact:EBI-6147978 intact:EBI-359141|uniprotkb:P23411|uniprotkb:B2R5A8|ensembl:ENSP00000309830|ensembl:ENSP00000390279|ensembl:ENSP00000434243 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl38_human(display_long)|uniprotkb:RPL38(gene name)|psi-mi:RPL38(display_short)|uniprotkb:Large ribosomal subunit protein eL38(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_000990.1|refseq:NP_001030335.1|ensembl:ENSG00000172809(gene)|ensembl:ENST00000311111(transcript)|ensembl:ENST00000439590(transcript)|ensembl:ENST00000533498(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022618"(ribonucleoprotein complex assembly)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0033291"(eukaryotic 80S initiation complex)|go:"GO:0034463"(90S preribosome assembly)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0048318"(axial mesoderm development)|interpro:IPR002675(Ribosomal protein L38e)|interpro:IPR038464|mint:P63173|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:5AJ0|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:6kUSGJll3ldTTRzgVTSwBjgV19Y9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P62913 intact:EBI-6147978 intact:EBI-354380|uniprotkb:P25121|uniprotkb:P39026|uniprotkb:Q8TDH2|uniprotkb:Q9Y674|ensembl:ENSP00000496250 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl11_human(display_long)|uniprotkb:RPL11(gene name)|psi-mi:RPL11(display_short)|uniprotkb:CLL-associated antigen KW-12(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_000966.2|refseq:NP_001186731.1|ensembl:ENSG00000142676(gene)|ensembl:ENST00000643754(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006605"(protein targeting)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR002132(Ribosomal protein L5)|interpro:IPR020929|interpro:IPR022803|interpro:IPR031309|interpro:IPR031310|mint:P62913|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4XXB|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y6X - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:xt8XhDkfQPoH4DIPr0gC+ll766Q9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P55265 intact:EBI-6147978 intact:EBI-2462104|uniprotkb:B1AQR0|uniprotkb:O15223|uniprotkb:O43859|uniprotkb:O43860|uniprotkb:Q9BYM3|uniprotkb:Q9BYM4|uniprotkb:B1AQQ9|uniprotkb:D3DV76|ensembl:ENSP00000357459 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:dsrad_human(display_long)|uniprotkb:ADAR(gene name)|psi-mi:ADAR(display_short)|uniprotkb:ADAR1(gene name synonym)|uniprotkb:DSRAD(gene name synonym)|uniprotkb:G1P1(gene name synonym)|uniprotkb:IFI4(gene name synonym)|uniprotkb:136 kDa double-stranded RNA-binding protein(gene name synonym)|uniprotkb:K88DSRBP(gene name synonym)|uniprotkb:Interferon-inducible protein 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001020278.1|refseq:NP_001102.2|refseq:NP_001180424.1|refseq:NP_056655.2|refseq:NP_056656.2|refseq:XP_006711174.1|refseq:XP_006711175.1|refseq:XP_006711176.1|dip:DIP-29310N|ensembl:ENSG00000160710(gene)|ensembl:ENST00000368474(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002566"(somatic diversification of immune receptors via somatic mutation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0008251"(tRNA-specific adenosine deaminase activity)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016553"(base conversion or substitution editing)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900369"(negative regulation of RNA interference)|interpro:IPR002466(Adenosine deaminase/editase)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371|interpro:IPR044456|interpro:IPR044457|mint:P55265|rcsb pdb:1QBJ|rcsb pdb:1QGP|rcsb pdb:1XMK|rcsb pdb:2ACJ|rcsb pdb:2GXB|rcsb pdb:2L54|rcsb pdb:2MDR|rcsb pdb:3F21|rcsb pdb:3F22|rcsb pdb:3F23|rcsb pdb:3IRQ|rcsb pdb:3IRR|rcsb pdb:5ZU1|rcsb pdb:5ZUO|rcsb pdb:5ZUP|rcsb pdb:7C0I|reactome:R-HSA-75102|reactome:R-HSA-77042|reactome:R-HSA-909733|go:"GO:0051607"(defense response to virus) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:rP/Yr/h8WLSFNdIuqWnYtZjZ9qI9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P46778 intact:EBI-6147978 intact:EBI-350634|uniprotkb:Q16699|ensembl:ENSP00000346027|ensembl:ENSP00000351021|ensembl:ENSP00000370569|ensembl:ENSP00000370574 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl21_human(display_long)|uniprotkb:RPL21(gene name)|psi-mi:RPL21(display_short)|uniprotkb:Large ribosomal subunit protein eL21(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) rcsb pdb:6LU8|refseq:NP_000973.2|ensembl:ENSG00000122026(gene)|ensembl:ENST00000272274(transcript)|ensembl:ENST00000311549(transcript)|ensembl:ENST00000319826(transcript)|ensembl:ENST00000326092(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001147(Ribosomal protein L21e)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018259|interpro:IPR036948|mint:P46778|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6OLE|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:UCth+WL9Oj1Y9I5m4i/9X0a5WHk9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:Q9UL40 intact:EBI-6147978 intact:EBI-2462313|uniprotkb:B7Z367|uniprotkb:Q68CV9|uniprotkb:Q6ZMW1|ensembl:ENSP00000350869 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:zn346_human(display_long)|uniprotkb:ZNF346(gene name)|psi-mi:ZNF346(display_short)|uniprotkb:JAZ(gene name synonym)|uniprotkb:Just another zinc finger protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001295142.1|refseq:NP_001295143.1|refseq:NP_001295148.1|refseq:NP_001295152.1|refseq:NP_036411.1|refseq:XP_016864784.1|refseq:XP_016864785.1|ensembl:ENSG00000113761(gene)|ensembl:ENST00000358149(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0035198"(miRNA binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|rcsb pdb:2MKD|rcsb pdb:2MKN - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:bK/y4NYSSsa1tcNjtbmsEmkSp7Q9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P61254 intact:EBI-6147978 intact:EBI-352405|uniprotkb:Q02877|uniprotkb:Q6IPY2|uniprotkb:B2R4F0|uniprotkb:D3DTR8|ensembl:ENSP00000462322|ensembl:ENSP00000463470|ensembl:ENSP00000463784|ensembl:ENSP00000498177 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl26_human(display_long)|uniprotkb:RPL26(gene name)|psi-mi:RPL26(display_short)|uniprotkb:Large ribosomal subunit protein uL24(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_000978.1|refseq:NP_001302459.1|refseq:NP_001302460.1|ensembl:ENST00000582556(transcript)|ensembl:ENST00000583011(transcript)|ensembl:ENST00000584164(transcript)|ensembl:ENST00000648839(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|ensembl:ENSG00000161970(gene)|go:"GO:0022626"(cytosolic ribosome)|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:1902167"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1904803"(regulation of translation involved in cellular response to UV)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005756(Ribosomal protein L26, eukaryotic/archaeal)|interpro:IPR005824(KOW)|interpro:IPR005825(Ribosomal protein L24/L26, conserved site)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041988|mint:P61254|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|go:"GO:0034644"(cellular response to UV)|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|rcsb pdb:5LKS|reactome:R-HSA-156827|dip:DIP-33198N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:VAROWOFmYvolVgc/e5E1jAmNuaY9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:Q96KK5 intact:EBI-6147978 intact:EBI-6147668|ensembl:ENSP00000366679 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a1h_human(display_long)|uniprotkb:H2AC12(gene name)|psi-mi:H2AC12(display_short)|uniprotkb:H2A-clustered histone 12(gene name synonym)|uniprotkb:HIST1H2AH(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:Histone H2A/s(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_542163.1|dip:DIP-61699N|ensembl:ENSG00000274997(gene)|ensembl:ENST00000377459(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:Oa322n+evy8Cu0E9cWTEdYwQPKM9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P35268 intact:EBI-6147978 intact:EBI-354533|intact:EBI-1055963|uniprotkb:Q6IBD1|uniprotkb:B2R495|ensembl:ENSP00000346088 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl22_human(display_long)|uniprotkb:RPL22(gene name)|psi-mi:RPL22(display_short)|uniprotkb:Heparin-binding protein HBp15(gene name synonym)|uniprotkb:Epstein-Barr virus small RNA-associated protein(gene name synonym)|uniprotkb:EBER-associated protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL22(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_000974.1|ensembl:ENSG00000116251(gene)|ensembl:ENST00000234875(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008201"(heparin binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0045182"(translation regulator activity)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099577"(regulation of translation at presynapse, modulating synaptic transmission)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002671(Ribosomal protein L22e)|interpro:IPR038526|mint:P35268|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|reactome:R-HSA-72706|rcsb pdb:6Z6L|rcsb pdb:6Z6M|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:0TVillnqDkHmdTwxIedAJCVAdzY9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P46783 intact:EBI-6147978 intact:EBI-354442|uniprotkb:Q5TZC0|uniprotkb:B2R4E3|ensembl:ENSP00000481646|ensembl:ENSP00000494190|ensembl:ENSP00000494440|ensembl:ENSP00000497917 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs10_human(display_long)|uniprotkb:RPS10(gene name)|psi-mi:RPS10(display_short)|uniprotkb:Small ribosomal subunit protein eS10(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001005.1|refseq:NP_001190174.1|refseq:NP_001191020.1|ensembl:ENSG00000124614(gene)|ensembl:ENST00000464218(transcript)|ensembl:ENST00000467531(transcript)|ensembl:ENST00000621356(transcript)|ensembl:ENST00000648437(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR005326(Plectin/S10, N-terminal)|rcsb pdb:6G51|interpro:IPR036388|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|interpro:IPR037447|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|mint:P46783|rcsb pdb:4UG0|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:4V6X|rcsb pdb:6ZUO|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|rcsb pdb:5T2C|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:GWUAJh7s0w/ar/SOpx0hiIJOr2c9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:Q969Q0 intact:EBI-6147978 intact:EBI-2877705|ensembl:ENSP00000346012|uniprotkb:Q3B7A5 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl36l_human(display_long)|uniprotkb:RPL36AL(gene name)|psi-mi:RPL36AL(display_short)|uniprotkb:Large ribosomal subunit protein eL42-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000165502(gene)|ensembl:ENST00000298289(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000552(Ribosomal protein L44e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:Q969Q0|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-9633012|refseq:NP_000992.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:+jT5oFy79StEavkvHz6j/36g/qg9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:Q99878 intact:EBI-6147978 intact:EBI-6147676|uniprotkb:Q5JXQ5|uniprotkb:A2RUU6|ensembl:ENSP00000328484 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a1j_human(display_long)|uniprotkb:H2AC14(gene name)|psi-mi:H2AC14(display_short)|uniprotkb:H2AFE(gene name synonym)|uniprotkb:HIST1H2AJ(gene name synonym)|uniprotkb:Histone H2A/e(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_066544.1|ensembl:ENSG00000276368(gene)|ensembl:ENST00000333151(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:tS29VG3PpglHaYbu0w5z7pGvYyI9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P36578 intact:EBI-6147978 intact:EBI-348313|ensembl:ENSP00000311430|uniprotkb:P39029|uniprotkb:Q4VBR0|uniprotkb:Q969Z9|uniprotkb:A8K502 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl4_human(display_long)|uniprotkb:RPL4(gene name)|psi-mi:RPL4(display_short)|uniprotkb:RPL1(gene name synonym)|uniprotkb:60S ribosomal protein L1(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000174444(gene)|ensembl:ENST00000307961(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002136(Ribosomal protein L4/L1e)|interpro:IPR013000(Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site)|interpro:IPR025755|mint:P36578|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|interpro:IPR023574|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6OM0|refseq:NP_000959.2|dip:DIP-27559N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:34il/jyrW0Dqj0eA8GBFgUk05XU9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P05386 intact:EBI-6147978 intact:EBI-354582|uniprotkb:A6NIB2|ensembl:ENSP00000346037 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rla1_human(display_long)|uniprotkb:RPLP1(gene name)|psi-mi:RPLP1(display_short)|uniprotkb:RRP1(gene name synonym)|uniprotkb:Large ribosomal subunit protein P1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_000994.1|refseq:NP_998890.1|ensembl:ENSG00000137818(gene)|ensembl:ENST00000260379(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR027534|interpro:IPR038716|mint:P05386|rcsb pdb:2LBF|rcsb pdb:4BEH|rcsb pdb:4V6X|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:rHSXz4ZCJy+JH6OrjUgHiTK85mo9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P04908 intact:EBI-6147978 intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:4Qno1mMYZB6FdNoojrzulWLVq849606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P30050 intact:EBI-6147978 intact:EBI-352743|uniprotkb:Q6PB27|uniprotkb:Q5VVV2|ensembl:ENSP00000354739 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl12_human(display_long)|uniprotkb:RPL12(gene name)|psi-mi:RPL12(display_short)|uniprotkb:Large ribosomal subunit protein uL11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_000967.1|ensembl:ENSG00000197958(gene)|ensembl:ENST00000361436(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|interpro:IPR000911(Ribosomal protein L11)|interpro:IPR020783|interpro:IPR020784|interpro:IPR020785|interpro:IPR036769|interpro:IPR036796|mint:P30050|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:TNPEtl60cILofaPzUznvZiw6D7E9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q0HD54 uniprotkb:P60866 intact:EBI-6147978 intact:EBI-353105|uniprotkb:P17075|uniprotkb:Q5M8S9|uniprotkb:B2R4F4|uniprotkb:B4DW28|ensembl:ENSP00000009589|ensembl:ENSP00000427788|ensembl:ENSP00000503327|ensembl:ENSP00000504123|ensembl:ENSP00000504154|ensembl:ENSP00000504670 psi-mi:ns1_i40a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs20_human(display_long)|uniprotkb:RPS20(gene name)|psi-mi:RPS20(display_short)|uniprotkb:Small ribosomal subunit protein uS10(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:383543(i40a0)|taxid:383543("Influenza A virus (strain A/Hickox/1940 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155110|imex:IM-17331-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001014.1|refseq:NP_001139699.1|dip:DIP-31245N|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|ensembl:ENSG00000008988(gene)|ensembl:ENST00000009589(transcript)|ensembl:ENST00000521262(transcript)|ensembl:ENST00000676461(transcript)|ensembl:ENST00000676918(transcript)|ensembl:ENST00000678039(transcript)|ensembl:ENST00000678683(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR001848(Ribosomal protein S10)|interpro:IPR005729(Ribosomal protein S10, eukaryotic/archaeal)|interpro:IPR018268|interpro:IPR027486|interpro:IPR036838|mint:P60866|rcsb pdb:4UG0|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:wqs0WZoIHv8xHRkDiWSS2rSs1b0383543 rogid:6xNxX+eP59AOm0KraCysRHUqMFw9606 intact-crc:E6E624CBBE1967D2|rigid:JFWThB6Iz3SOySBoPpbbkH+ilDY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q96FJ2 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-742371|uniprotkb:B2R5B4|ensembl:ENSP00000477310 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:dyl2_human(display_long)|uniprotkb:DYNLL2(gene name)|psi-mi:DYNLL2(display_short)|uniprotkb:Dynein light chain LC8-type 2(gene name synonym)|uniprotkb:DLC2(gene name synonym)|uniprotkb:8 kDa dynein light chain b(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155404|imex:IM-17331-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP go:"GO:0005813"(centrosome)|refseq:NP_542408.1|ensembl:ENSG00000264364(gene)|ensembl:ENST00000579991(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007017"(microtubule-based process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0031475"(myosin V complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:Q96FJ2|rcsb pdb:2XQQ|rcsb pdb:3P8M|rcsb pdb:4D07|reactome:R-HSA-139910|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:4RFpJF40RBja5mOvt/aCv3miiDU9606 intact-crc:35EFAFEC280F4111|rigid:iZkNhkmATQn5qTmJmHdRaaXxbhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P22626 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155404|imex:IM-17331-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606 intact-crc:35EFAFEC280F4111|rigid:iZkNhkmATQn5qTmJmHdRaaXxbhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:O95816 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155404|imex:IM-17331-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606 intact-crc:35EFAFEC280F4111|rigid:iZkNhkmATQn5qTmJmHdRaaXxbhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P12036 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-2880271|uniprotkb:Q9UQ14|uniprotkb:Q9UJS7|uniprotkb:Q96HF8|uniprotkb:B4DYY4|ensembl:ENSP00000311997 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:nfh_human(display_long)|uniprotkb:NEFH(gene name)|psi-mi:NEFH(display_short)|uniprotkb:KIAA0845(gene name synonym)|uniprotkb:NFH(gene name synonym)|uniprotkb:200 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament triplet H protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155404|imex:IM-17331-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_066554.2|ensembl:ENSG00000100285(gene)|ensembl:ENST00000310624(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005883"(neurofilament)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0061564"(axon development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR010790(Protein of unknown function DUF1388)|interpro:IPR018039|interpro:IPR033183|interpro:IPR039008|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:TXMrn6SWBHIYQY1loZfVvMo9PtU9606 intact-crc:35EFAFEC280F4111|rigid:iZkNhkmATQn5qTmJmHdRaaXxbhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P05388 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-354101|uniprotkb:Q9BVK4|intact:EBI-8012155|intact:MINT-8395053|uniprotkb:Q3B7A4|ensembl:ENSP00000339027|ensembl:ENSP00000376299|ensembl:ENSP00000449328 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:rla0_human(display_long)|uniprotkb:RPLP0(gene name)|psi-mi:RPLP0(display_short)|uniprotkb:60S ribosomal protein L10E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL10(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155404|imex:IM-17331-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_000993.1|refseq:NP_444505.1|ensembl:ENSG00000089157(gene)|ensembl:ENST00000228306(transcript)|ensembl:ENST00000392514(transcript)|ensembl:ENST00000551150(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0098794"(postsynapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR030670|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:P05388|rcsb pdb:4V6W|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8950505|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:xv3QHqnXxvCd3BOIeHVkqEnSNNk9606 intact-crc:35EFAFEC280F4111|rigid:iZkNhkmATQn5qTmJmHdRaaXxbhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P63167 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155404|imex:IM-17331-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606 intact-crc:35EFAFEC280F4111|rigid:iZkNhkmATQn5qTmJmHdRaaXxbhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P35637 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-400434|uniprotkb:Q9H4A8|ensembl:ENSP00000254108 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:fus_human(display_long)|uniprotkb:FUS(gene name)|psi-mi:FUS(display_short)|uniprotkb:TLS(gene name synonym)|uniprotkb:Oncogene FUS(gene name synonym)|uniprotkb:Oncogene TLS(gene name synonym)|uniprotkb:Translocated in liposarcoma protein(gene name synonym)|uniprotkb:POMp75(gene name synonym)|uniprotkb:75 kDa DNA-pairing protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155404|imex:IM-17331-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_001164105.1|refseq:NP_004951.1|ensembl:ENSG00000089280(gene)|ensembl:ENST00000254108(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008380"(RNA splicing)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044327"(dendritic spine head)|go:"GO:0046872"(metal ion binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034459|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:P35637|rcsb pdb:2LA6|rcsb pdb:2LCW|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:5W3N|rcsb pdb:5XRR|rcsb pdb:5XSG|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:6BWZ|rcsb pdb:6BXV|rcsb pdb:6BZP|rcsb pdb:6G99|rcsb pdb:6GBM|rcsb pdb:6KJ1|rcsb pdb:6KJ2|rcsb pdb:6KJ3|rcsb pdb:6KJ4|rcsb pdb:6SNJ|rcsb pdb:6XFM|rcsb pdb:7CYL|reactome:R-HSA-72163|dip:DIP-29857N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:HUP4fGXQyJnm5CFTuwjTpiucZOc9606 intact-crc:35EFAFEC280F4111|rigid:iZkNhkmATQn5qTmJmHdRaaXxbhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P30050 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-352743|uniprotkb:Q6PB27|uniprotkb:Q5VVV2|ensembl:ENSP00000354739 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:rl12_human(display_long)|uniprotkb:RPL12(gene name)|psi-mi:RPL12(display_short)|uniprotkb:Large ribosomal subunit protein uL11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155404|imex:IM-17331-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_000967.1|ensembl:ENSG00000197958(gene)|ensembl:ENST00000361436(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|interpro:IPR000911(Ribosomal protein L11)|interpro:IPR020783|interpro:IPR020784|interpro:IPR020785|interpro:IPR036769|interpro:IPR036796|mint:P30050|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:TNPEtl60cILofaPzUznvZiw6D7E9606 intact-crc:35EFAFEC280F4111|rigid:iZkNhkmATQn5qTmJmHdRaaXxbhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q6P2E9 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155404|imex:IM-17331-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP ensembl:ENSG00000038358(gene)|interpro:IPR036322|mint:Q6P2E9|reactome:R-HSA-430039|ensembl:ENST00000358933(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|refseq:NP_055144.3|dip:DIP-31192N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606 intact-crc:35EFAFEC280F4111|rigid:iZkNhkmATQn5qTmJmHdRaaXxbhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q9BQE3 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155404|imex:IM-17331-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:35EFAFEC280F4111|rigid:iZkNhkmATQn5qTmJmHdRaaXxbhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q8WWM7 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-948363|ensembl:ENSP00000338718|uniprotkb:O95135|uniprotkb:Q6NVJ8|uniprotkb:Q6PJW6|uniprotkb:Q8IU61|uniprotkb:Q8IU95|uniprotkb:Q8WWM3|uniprotkb:Q8WWM4|uniprotkb:Q8WWM5|uniprotkb:Q8WWM6|uniprotkb:Q99703|uniprotkb:B9EGM2|uniprotkb:E9PAR9|uniprotkb:A8K1R6|uniprotkb:Q63ZY4 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:atx2l_human(display_long)|uniprotkb:Ataxin-2 domain protein(gene name synonym)|uniprotkb:Ataxin-2-related protein(gene name synonym)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short)|uniprotkb:A2D(gene name synonym)|uniprotkb:A2LG(gene name synonym)|uniprotkb:A2LP(gene name synonym)|uniprotkb:A2RP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155404|imex:IM-17331-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP ensembl:ENSG00000168488(gene)|ensembl:ENST00000336783(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045296"(cadherin binding)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR025852|mint:Q8WWM7|refseq:NP_009176.2|refseq:NP_663760.1|refseq:NP_680780.1|refseq:NP_680781.1|refseq:XP_005255123.1|refseq:NP_059867.3|refseq:NP_680782.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:t7lrS10IM/5pt+rrbqBRowZ6b+09606 intact-crc:35EFAFEC280F4111|rigid:iZkNhkmATQn5qTmJmHdRaaXxbhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P12273 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-1049746|uniprotkb:A0A963|uniprotkb:A0A9C3|uniprotkb:A0A9F3|uniprotkb:A4D2I1|ensembl:ENSP00000291009 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:pip_human(display_long)|uniprotkb:Prolactin-induced protein(gene name synonym)|uniprotkb:Secretory actin-binding protein(gene name synonym)|uniprotkb:Gross cystic disease fluid protein 15(gene name synonym)|uniprotkb:gp17(gene name synonym)|uniprotkb:PIP(gene name)|psi-mi:PIP(display_short)|uniprotkb:GCDFP15(gene name synonym)|uniprotkb:GPIP4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155404|imex:IM-17331-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_002643.1|ensembl:ENSG00000159763(gene)|ensembl:ENST00000291009(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0003779"(actin binding)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006508"(proteolysis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019864"(IgG binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|interpro:IPR007990(Seminal vesicle autoantigen)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|mint:P12273|rcsb pdb:3ES6|reactome:R-HSA-5223345|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:/OC16zeRzFp520uPPLHh+WekPPc9606 intact-crc:35EFAFEC280F4111|rigid:iZkNhkmATQn5qTmJmHdRaaXxbhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q71U36 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155404|imex:IM-17331-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 intact-crc:35EFAFEC280F4111|rigid:iZkNhkmATQn5qTmJmHdRaaXxbhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P05386 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-354582|uniprotkb:A6NIB2|ensembl:ENSP00000346037 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:rla1_human(display_long)|uniprotkb:RPLP1(gene name)|psi-mi:RPLP1(display_short)|uniprotkb:RRP1(gene name synonym)|uniprotkb:Large ribosomal subunit protein P1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155404|imex:IM-17331-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_000994.1|refseq:NP_998890.1|ensembl:ENSG00000137818(gene)|ensembl:ENST00000260379(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR027534|interpro:IPR038716|mint:P05386|rcsb pdb:2LBF|rcsb pdb:4BEH|rcsb pdb:4V6X|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:rHSXz4ZCJy+JH6OrjUgHiTK85mo9606 intact-crc:35EFAFEC280F4111|rigid:iZkNhkmATQn5qTmJmHdRaaXxbhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01639 uniprotkb:P17066 intact:EBI-6148279|uniprotkb:Q9YMF4|uniprotkb:Q9YMF5|uniprotkb:A7BHX8 intact:EBI-355106|uniprotkb:Q8IYK7|uniprotkb:Q9BT95|uniprotkb:Q1HBA8|ensembl:ENSP00000310219 psi-mi:ns1_incaa(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hsp76_human(display_long)|uniprotkb:HSPA6(gene name)|psi-mi:HSPA6(display_short)|uniprotkb:HSP70B'(gene name synonym)|uniprotkb:Heat shock 70 kDa protein B'(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11553(incaa)|taxid:11553("Influenza C virus (strain C/Ann Arbor/1/1950)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155395|imex:IM-17331-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005187(Influenza C non-structural protein NS1)|interpro:IPR005188(Influenza C non-structural protein NS2)|refseq:YP_002302329.1|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0042025"(host cell nucleus) refseq:NP_002146.2|ensembl:ENSG00000173110(gene)|ensembl:ENST00000309758(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P17066|rcsb pdb:3FE1|reactome:R-HSA-3371453|reactome:R-HSA-6798695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:hHaC2kg2bQJV+vBe66TDz4ZoCzQ11553 rogid:AcNwJ2S/RD3n/8iRNy5ioetVZ+U9606 intact-crc:2B99255722EDE82E|rigid:Bjh1St082pncB+d5z7nNbiqT4c8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P05141 intact:EBI-6148200 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155326|imex:IM-17331-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:E43A670489384118|rigid:M0NXB95ZSqFk6AVa64WHUPDA2pk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P23396 intact:EBI-6148200 intact:EBI-351193|uniprotkb:Q498B5|uniprotkb:Q8NI95|uniprotkb:B2R7N5|ensembl:ENSP00000433821|ensembl:ENSP00000434643|ensembl:ENSP00000436971|uniprotkb:J3KN86 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:rs3_human(display_long)|uniprotkb:RPS3(gene name)|psi-mi:RPS3(display_short)|uniprotkb:Small ribosomal subunit protein uS3(gene name synonym)|uniprotkb:OK/SW-cl.26(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155326|imex:IM-17331-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_000996.2|ensembl:ENSG00000149273(gene)|ensembl:ENST00000524851(transcript)|ensembl:ENST00000527446(transcript)|ensembl:ENST00000531188(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR004044(K Homology, type 2)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|go:"GO:0071159"(NF-kappaB complex)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR018280|interpro:IPR036419|mint:P23396|rcsb pdb:1WH9|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|rcsb pdb:6QZP|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|refseq:NP_001243731.1|refseq:NP_001247436.1|refseq:NP_001247435.1|dip:DIP-33177N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:fsDW18AMR3YyEEIhMVcngYRWkps9606 intact-crc:E43A670489384118|rigid:M0NXB95ZSqFk6AVa64WHUPDA2pk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:Q08380 intact:EBI-6148200 intact:EBI-354956|ensembl:ENSP00000262776|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155326|imex:IM-17331-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" ensembl:ENSG00000108679(gene)|ensembl:ENST00000262776(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017448(Speract/scavenger receptor related)|go:"GO:0007155"(cell adhesion)|interpro:IPR036772|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|refseq:NP_005558.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606 intact-crc:E43A670489384118|rigid:M0NXB95ZSqFk6AVa64WHUPDA2pk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:Q6NSJ2 intact:EBI-6148200 intact:EBI-6148204|uniprotkb:Q8N7Z4|ensembl:ENSP00000292140 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:phlb3_human(display_long)|uniprotkb:PHLDB3(gene name)|psi-mi:PHLDB3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155326|imex:IM-17331-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_942147.3|ensembl:ENSG00000176531(gene)|ensembl:ENST00000292140(transcript)|go:"GO:0019899"(enzyme binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037810 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:mHR2QwOa65vWru5ZUAnRSjMU8lU9606 intact-crc:E43A670489384118|rigid:M0NXB95ZSqFk6AVa64WHUPDA2pk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:Q05639 intact:EBI-6148200 intact:EBI-354943|ensembl:ENSP00000217182|uniprotkb:P54266|uniprotkb:Q0VGC7|uniprotkb:B5BUF3|uniprotkb:E1P5J1 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:ef1a2_human(display_long)|uniprotkb:EEF1A2(gene name)|psi-mi:EEF1A2(display_short)|uniprotkb:EEF1AL(gene name synonym)|uniprotkb:STN(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-2(gene name synonym)|uniprotkb:Statin-S1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155326|imex:IM-17331-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" ensembl:ENSG00000101210(gene)|ensembl:ENST00000217182(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0090218"(positive regulation of lipid kinase activity)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:Q05639|rcsb pdb:3C5J|reactome:R-HSA-156842|refseq:NP_001949.1|dip:DIP-40060N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:vFXfcSRokxKo5RW0tRE1qEK0NKw9606 intact-crc:E43A670489384118|rigid:M0NXB95ZSqFk6AVa64WHUPDA2pk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P07437 intact:EBI-6148200 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155326|imex:IM-17331-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:E43A670489384118|rigid:M0NXB95ZSqFk6AVa64WHUPDA2pk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:Q16543 intact:EBI-6148200 intact:EBI-295634|uniprotkb:Q53YA2|ensembl:ENSP00000222005 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:cdc37_human(display_long)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:p50Cdc37(gene name synonym)|uniprotkb:CDC37A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155326|imex:IM-17331-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_008996.1|dip:DIP-27560N|ensembl:ENSG00000105401(gene)|ensembl:ENST00000222005(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006605"(protein targeting)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0101031"(chaperone complex)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|mint:Q16543|rcsb pdb:1US7|rcsb pdb:2K5B|rcsb pdb:2N5X|rcsb pdb:2NCA|rcsb pdb:2W0G|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5HPE|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-9013418|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:iajhitd2iEmd17KfpU/nMaKc4049606 intact-crc:E43A670489384118|rigid:M0NXB95ZSqFk6AVa64WHUPDA2pk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P08238 intact:EBI-6148200 intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155326|imex:IM-17331-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:wOsW7C10v2oMsM+REE38K6PAan09606 intact-crc:E43A670489384118|rigid:M0NXB95ZSqFk6AVa64WHUPDA2pk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P62269 intact:EBI-6148200 intact:EBI-352451|ensembl:ENSP00000211372|ensembl:ENSP00000393241|ensembl:ENSP00000403175|ensembl:ENSP00000412583|ensembl:ENSP00000416110|uniprotkb:P25232|uniprotkb:Q6IPF8|uniprotkb:Q5SUJ3 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:rs18_human(display_long)|uniprotkb:RPS18(gene name)|psi-mi:RPS18(display_short)|uniprotkb:D6S218E(gene name synonym)|uniprotkb:Ke-3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS13(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155326|imex:IM-17331-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_072045.1|ensembl:ENSG00000096150(gene)|ensembl:ENSG00000223367(gene)|ensembl:ENSG00000226225(gene)|ensembl:ENSG00000231500(gene)|ensembl:ENSG00000235650(gene)|ensembl:ENST00000211372(transcript)|ensembl:ENST00000434122(transcript)|ensembl:ENST00000439602(transcript)|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENST00000454021(transcript)|ensembl:ENST00000457341(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001892(Ribosomal protein S13)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR018269|interpro:IPR027437|mint:P62269|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|dip:DIP-32892N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:yOHgKM/BuvgGdqp1OEVPeuiABg89606 intact-crc:E43A670489384118|rigid:M0NXB95ZSqFk6AVa64WHUPDA2pk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P68104 intact:EBI-6148200 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155326|imex:IM-17331-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 intact-crc:E43A670489384118|rigid:M0NXB95ZSqFk6AVa64WHUPDA2pk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P78371 intact:EBI-6148200 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155326|imex:IM-17331-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:E43A670489384118|rigid:M0NXB95ZSqFk6AVa64WHUPDA2pk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P50990 intact:EBI-6148200 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155326|imex:IM-17331-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 intact-crc:E43A670489384118|rigid:M0NXB95ZSqFk6AVa64WHUPDA2pk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P07900 intact:EBI-6148200 intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|ensembl:ENSP00000216281|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155326|imex:IM-17331-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" go:"GO:0009409"(response to cold)|go:"GO:0016020"(membrane)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|ensembl:ENST00000216281(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000080824(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043335"(protein unfolding)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1UY8|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2BYH|rcsb pdb:2VCJ|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3B24|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5LO1|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6CYH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7LSZ|rcsb pdb:7LT0|reactome:R-HSA-1227986|reactome:R-HSA-1236382|rcsb pdb:6TN4|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9665233|reactome:R-HSA-9664565|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3K99|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:3T0H|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:4YKZ|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|refseq:NP_001017963.2|refseq:NP_005339.3|dip:DIP-27595N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606 intact-crc:E43A670489384118|rigid:M0NXB95ZSqFk6AVa64WHUPDA2pk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:Q5VTE0 intact:EBI-6148200 intact:EBI-877809 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:ef1a3_human(display_long)|uniprotkb:EEF1A1P5(gene name)|psi-mi:EEF1A1P5(display_short)|uniprotkb:Eukaryotic elongation factor 1 A-like 3(gene name synonym)|uniprotkb:EEF1AL3(gene name synonym)|uniprotkb:Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155326|imex:IM-17331-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR031157|reactome:R-HSA-156842|interpro:IPR027417 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:3t6tj3i+3CKTC1NsrHyBkeoRK789606 intact-crc:E43A670489384118|rigid:M0NXB95ZSqFk6AVa64WHUPDA2pk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:O14654 intact:EBI-6148200 intact:EBI-356594|ensembl:ENSP00000505547 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155326|imex:IM-17331-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606 intact-crc:E43A670489384118|rigid:M0NXB95ZSqFk6AVa64WHUPDA2pk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P40227 intact:EBI-6148200 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155326|imex:IM-17331-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 intact-crc:E43A670489384118|rigid:M0NXB95ZSqFk6AVa64WHUPDA2pk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P50991 intact:EBI-6148200 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155326|imex:IM-17331-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 intact-crc:E43A670489384118|rigid:M0NXB95ZSqFk6AVa64WHUPDA2pk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P12236 intact:EBI-6148200 intact:EBI-356254|ensembl:ENSP00000370808|uniprotkb:Q96C49 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155326|imex:IM-17331-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" ensembl:ENSG00000169100(gene)|ensembl:ENST00000381401(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|refseq:NP_001627.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606 intact-crc:E43A670489384118|rigid:M0NXB95ZSqFk6AVa64WHUPDA2pk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P17987 intact:EBI-6148200 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155326|imex:IM-17331-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 intact-crc:E43A670489384118|rigid:M0NXB95ZSqFk6AVa64WHUPDA2pk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P49368 intact:EBI-6148200 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155326|imex:IM-17331-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:E43A670489384118|rigid:M0NXB95ZSqFk6AVa64WHUPDA2pk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:Q9BUJ2 intact:EBI-6148200 intact:EBI-1018153|uniprotkb:O76022|uniprotkb:Q6ZSZ0|uniprotkb:Q7L8P4|uniprotkb:Q8N6Z4|uniprotkb:Q96G37|uniprotkb:Q9HAL3|uniprotkb:Q9UG75|intact:EBI-3183399|intact:EBI-2339292|uniprotkb:B3KMW7|ensembl:ENSP00000375863|intact:EBI-2563529 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:hnrl1_human(display_long)|uniprotkb:E1BAP5(gene name synonym)|uniprotkb:HNRNPUL1(gene name)|psi-mi:HNRNPUL1(display_short)|uniprotkb:HNRPUL1(gene name synonym)|uniprotkb:Adenovirus early region 1B-associated protein 5(gene name synonym)|uniprotkb:E1B-55 kDa-associated protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155326|imex:IM-17331-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_008971.2|refseq:NP_653333.1|go:"GO:0009615"(response to virus)|go:"GO:0019899"(enzyme binding)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027025|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q9BUJ2|reactome:R-HSA-72163|ensembl:ENSG00000105323(gene)|ensembl:ENST00000392006(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|refseq:NP_001308140.1|refseq:NP_001308137.1|dip:DIP-39419N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:IahA7SVR1NmvldrWKQlAwApinQE9606 intact-crc:E43A670489384118|rigid:M0NXB95ZSqFk6AVa64WHUPDA2pk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P10225 uniprotkb:P19474 intact:EBI-6148417|uniprotkb:Q82170|uniprotkb:Q09I92 intact:EBI-81290|uniprotkb:Q96RF8|uniprotkb:Q5XPV5|ensembl:ENSP00000254436 psi-mi:shut_hhv11(display_long)|uniprotkb:UL41(gene name)|psi-mi:UL41(display_short) psi-mi:ro52_human(display_long)|uniprotkb:TRIM21(gene name)|psi-mi:TRIM21(display_short)|uniprotkb:RNF81(gene name synonym)|uniprotkb:Sjoegren syndrome type A antigen(gene name synonym)|uniprotkb:"Ro(SS-A)"(gene name synonym)|uniprotkb:52 kDa ribonucleoprotein autoantigen Ro/SS-A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 21(gene name synonym)|uniprotkb:RING finger protein 81(gene name synonym)|uniprotkb:52 kDa Ro protein(gene name synonym)|uniprotkb:RO52(gene name synonym)|uniprotkb:SSA1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM21(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155523|imex:IM-17331-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-57855N|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039595"(induction by virus of catabolism of host mRNA)|go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR006086(XPG I)|interpro:IPR029060 refseq:NP_003132.2|go:"GO:0019901"(protein kinase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031648"(protein destabilization)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090086"(negative regulation of protein deubiquitination)|ensembl:ENSG00000132109(gene)|ensembl:ENST00000254436(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000932"(P-body)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035831|interpro:IPR043136|mint:P19474|rcsb pdb:2IWG|rcsb pdb:5JPX|rcsb pdb:5OLM|rcsb pdb:6FGA|rcsb pdb:6S53|rcsb pdb:7BBD|reactome:R-HSA-1834941|reactome:R-HSA-3134975|reactome:R-HSA-877300|reactome:R-HSA-983168|go:"GO:1902187"|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003613(U box)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:WTLHj+wKggCJsTkRWqliyRjHmuk10299 rogid:/9rpwdudXQWv8z8JLmRecXf3YQM9606 intact-crc:A8596F69D6DF3AFC|rigid:EjrIc4L45LBQAIH+UB3gkJwUK+A false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P10225 uniprotkb:P07437 intact:EBI-6148417|uniprotkb:Q82170|uniprotkb:Q09I92 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:shut_hhv11(display_long)|uniprotkb:UL41(gene name)|psi-mi:UL41(display_short) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155523|imex:IM-17331-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-57855N|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039595"(induction by virus of catabolism of host mRNA)|go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR006086(XPG I)|interpro:IPR029060 refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:WTLHj+wKggCJsTkRWqliyRjHmuk10299 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:A8596F69D6DF3AFC|rigid:EjrIc4L45LBQAIH+UB3gkJwUK+A false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P10225 uniprotkb:O95816 intact:EBI-6148417|uniprotkb:Q82170|uniprotkb:Q09I92 intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407 psi-mi:shut_hhv11(display_long)|uniprotkb:UL41(gene name)|psi-mi:UL41(display_short) psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155523|imex:IM-17331-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-57855N|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039595"(induction by virus of catabolism of host mRNA)|go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR006086(XPG I)|interpro:IPR029060 refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:WTLHj+wKggCJsTkRWqliyRjHmuk10299 rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606 intact-crc:A8596F69D6DF3AFC|rigid:EjrIc4L45LBQAIH+UB3gkJwUK+A false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P10225 uniprotkb:O14782 intact:EBI-6148417|uniprotkb:Q82170|uniprotkb:Q09I92 intact:EBI-1104854|uniprotkb:Q562F7|uniprotkb:O43544|uniprotkb:Q4ZG18|uniprotkb:Q53SX5|ensembl:ENSP00000264712|ensembl:ENSP00000385030 psi-mi:shut_hhv11(display_long)|uniprotkb:UL41(gene name)|psi-mi:UL41(display_short) psi-mi:kif3c_human(display_long)|uniprotkb:KIF3C(gene name)|psi-mi:KIF3C(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155523|imex:IM-17331-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-57855N|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039595"(induction by virus of catabolism of host mRNA)|go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR006086(XPG I)|interpro:IPR029060 go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0072384"(organelle transport along microtubule)|go:"GO:0097542"(ciliary tip)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|rcsb pdb:3B6V|reactome:R-HSA-2132295|reactome:R-HSA-5620924|reactome:R-HSA-6811434|reactome:R-HSA-983189|ensembl:ENSG00000084731(gene)|ensembl:ENST00000264712(transcript)|ensembl:ENST00000405914(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|refseq:NP_002245.4 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:WTLHj+wKggCJsTkRWqliyRjHmuk10299 rogid:Tx0u516rdJ0MvB7s2hyoRXIbb7A9606 intact-crc:A8596F69D6DF3AFC|rigid:EjrIc4L45LBQAIH+UB3gkJwUK+A false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P10225 uniprotkb:Q15056 intact:EBI-6148417|uniprotkb:Q82170|uniprotkb:Q09I92 intact:EBI-748492|uniprotkb:A8K3R1|uniprotkb:D3DXF6|uniprotkb:D3DXF8|ensembl:ENSP00000265753 psi-mi:shut_hhv11(display_long)|uniprotkb:UL41(gene name)|psi-mi:UL41(display_short) psi-mi:if4h_human(display_long)|uniprotkb:Williams-Beuren syndrome chromosomal region 1 protein(gene name synonym)|uniprotkb:EIF4H(gene name)|psi-mi:EIF4H(display_short)|uniprotkb:WBSCR1(gene name synonym)|uniprotkb:KIAA0038(gene name synonym)|uniprotkb:WSCR1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155523|imex:IM-17331-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-57855N|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039595"(induction by virus of catabolism of host mRNA)|go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR006086(XPG I)|interpro:IPR029060 refseq:NP_071496.1|refseq:NP_114381.1|ensembl:ENSG00000106682(gene)|ensembl:ENST00000265753(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0019953"(sexual reproduction)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034057"(RNA strand-exchange activity)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048589"(developmental growth)|go:"GO:0097010"(eukaryotic translation initiation factor 4F complex assembly)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034229|interpro:IPR035979|mint:Q15056|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:WTLHj+wKggCJsTkRWqliyRjHmuk10299 rogid:dNPoAzwFD5lFwCMnRl0cbXM3j8s9606 intact-crc:A8596F69D6DF3AFC|rigid:EjrIc4L45LBQAIH+UB3gkJwUK+A false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P10225 uniprotkb:Q08380 intact:EBI-6148417|uniprotkb:Q82170|uniprotkb:Q09I92 intact:EBI-354956|ensembl:ENSP00000262776|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0 psi-mi:shut_hhv11(display_long)|uniprotkb:UL41(gene name)|psi-mi:UL41(display_short) psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155523|imex:IM-17331-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-57855N|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0039595"(induction by virus of catabolism of host mRNA)|go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR006086(XPG I)|interpro:IPR029060 ensembl:ENSG00000108679(gene)|ensembl:ENST00000262776(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017448(Speract/scavenger receptor related)|go:"GO:0007155"(cell adhesion)|interpro:IPR036772|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|refseq:NP_005558.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:WTLHj+wKggCJsTkRWqliyRjHmuk10299 rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606 intact-crc:A8596F69D6DF3AFC|rigid:EjrIc4L45LBQAIH+UB3gkJwUK+A false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:Q08380 intact:EBI-6148200 intact:EBI-354956|ensembl:ENSP00000262776|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155452|imex:IM-17331-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" ensembl:ENSG00000108679(gene)|ensembl:ENST00000262776(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017448(Speract/scavenger receptor related)|go:"GO:0007155"(cell adhesion)|interpro:IPR036772|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|refseq:NP_005558.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606 intact-crc:3085053AB2F28C05|rigid:heL7zItAfEcdxAI8U0D1dXohfEg false mutation:220-220|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:Q8NF91 intact:EBI-6148200 intact:EBI-928867|uniprotkb:E7EQI5|uniprotkb:O94890|uniprotkb:Q5JV19|uniprotkb:Q5JV22|uniprotkb:Q8N9P7|uniprotkb:Q8TCP1|uniprotkb:Q8WWW6|uniprotkb:Q8WWW7|uniprotkb:Q8WXF6|uniprotkb:Q96N17|uniprotkb:Q9C0A7|uniprotkb:Q9H525|uniprotkb:Q9H526|uniprotkb:Q9NS36|uniprotkb:Q9NU50|uniprotkb:Q9UJ06|uniprotkb:Q9UJ07|uniprotkb:Q9ULF8|uniprotkb:B3W695|uniprotkb:H0Y4C0|uniprotkb:Q3ZCV0|ensembl:ENSP00000356224 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:syne1_human(display_long)|uniprotkb:SYNE1(gene name)|psi-mi:SYNE1(display_short)|uniprotkb:KIAA0796(gene name synonym)|uniprotkb:KIAA1262(gene name synonym)|uniprotkb:KIAA1756(gene name synonym)|uniprotkb:MYNE1(gene name synonym)|uniprotkb:Nuclear envelope spectrin repeat protein 1(gene name synonym)|uniprotkb:Synaptic nuclear envelope protein 1(gene name synonym)|uniprotkb:Myocyte nuclear envelope protein 1(gene name synonym)|uniprotkb:C6orf98(gene name synonym)|uniprotkb:Enaptin(gene name synonym)|uniprotkb:KASH domain-containing protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155452|imex:IM-17331-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_001334631.1|refseq:NP_149062.1|refseq:NP_892006.3|ensembl:ENSG00000131018(gene)|ensembl:ENST00000367255(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006997"(nucleus organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030017"(sarcomere)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051015"(actin filament binding)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR012315(Klarsicht/ANC-1/syne-1 homology)|interpro:IPR018159|interpro:IPR036872|mint:Q8NF91|rcsb pdb:4DXR|rcsb pdb:6R15|rcsb pdb:6XF2|reactome:R-HSA-1221632 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:6nWMBf60nycHwNcMMQJL5JqanEc9606 intact-crc:3085053AB2F28C05|rigid:heL7zItAfEcdxAI8U0D1dXohfEg false mutation:220-220|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:Q16543 intact:EBI-6148200 intact:EBI-295634|uniprotkb:Q53YA2|ensembl:ENSP00000222005 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:cdc37_human(display_long)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:p50Cdc37(gene name synonym)|uniprotkb:CDC37A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155452|imex:IM-17331-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_008996.1|dip:DIP-27560N|ensembl:ENSG00000105401(gene)|ensembl:ENST00000222005(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006605"(protein targeting)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0101031"(chaperone complex)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|mint:Q16543|rcsb pdb:1US7|rcsb pdb:2K5B|rcsb pdb:2N5X|rcsb pdb:2NCA|rcsb pdb:2W0G|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5HPE|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-9013418|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:iajhitd2iEmd17KfpU/nMaKc4049606 intact-crc:3085053AB2F28C05|rigid:heL7zItAfEcdxAI8U0D1dXohfEg false mutation:220-220|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P05141 intact:EBI-6148200 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155452|imex:IM-17331-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:3085053AB2F28C05|rigid:heL7zItAfEcdxAI8U0D1dXohfEg false mutation:220-220|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P24666 intact:EBI-6148200 intact:EBI-717701|uniprotkb:P24667|uniprotkb:Q16035|uniprotkb:Q53RU0|uniprotkb:Q16036|uniprotkb:Q16725|uniprotkb:Q3KQX8|uniprotkb:A8K1L9|uniprotkb:B5MCC7|ensembl:ENSP00000272065 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:ppac_human(display_long)|uniprotkb:Low molecular weight cytosolic acid phosphatase(gene name synonym)|uniprotkb:Red cell acid phosphatase 1(gene name synonym)|uniprotkb:Adipocyte acid phosphatase(gene name synonym)|uniprotkb:ACP1(gene name)|psi-mi:ACP1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155452|imex:IM-17331-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_004291.1|refseq:NP_009030.1|ensembl:ENSG00000143727(gene)|ensembl:ENST00000272065(transcript)|go:"GO:0003993"(acid phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002115(Protein-tyrosine phosphatase, low molecular weight, mammalian)|interpro:IPR017867|interpro:IPR023485|interpro:IPR036196|mint:P24666|rcsb pdb:1XWW|rcsb pdb:3N8I|rcsb pdb:4Z99|rcsb pdb:4Z9A|rcsb pdb:4Z9B|rcsb pdb:5JNR|rcsb pdb:5JNS|rcsb pdb:5JNT|rcsb pdb:5KQG|rcsb pdb:5KQL|rcsb pdb:5KQM|rcsb pdb:5KQP|rcsb pdb:5PNT|rcsb pdb:6Y2V|rcsb pdb:6Y2W|rcsb pdb:7KH8 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:j4VyGaaWO8l/Ah8i1HBU6EnbK289606 intact-crc:3085053AB2F28C05|rigid:heL7zItAfEcdxAI8U0D1dXohfEg false mutation:220-220|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P55795 intact:EBI-6148200 intact:EBI-352823|ensembl:ENSP00000361927|uniprotkb:Q9HHA7|uniprotkb:A1L400 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:hnrh2_human(display_long)|uniprotkb:HNRNPH2(gene name)|psi-mi:HNRNPH2(display_short)|uniprotkb:FTP3(gene name synonym)|uniprotkb:HNRPH2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein H'(gene name synonym)|uniprotkb:FTP-3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155452|imex:IM-17331-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" ensembl:ENSG00000126945(gene)|ensembl:ENST00000316594(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P55795|rcsb pdb:1WEZ|rcsb pdb:1WG5|rcsb pdb:6DG1|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001027565.1|refseq:NP_062543.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:811j5syFsbk/QSaZv/ag9QsFUEQ9606 intact-crc:3085053AB2F28C05|rigid:heL7zItAfEcdxAI8U0D1dXohfEg false mutation:220-220|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P62269 intact:EBI-6148200 intact:EBI-352451|ensembl:ENSP00000211372|ensembl:ENSP00000393241|ensembl:ENSP00000403175|ensembl:ENSP00000412583|ensembl:ENSP00000416110|uniprotkb:P25232|uniprotkb:Q6IPF8|uniprotkb:Q5SUJ3 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:rs18_human(display_long)|uniprotkb:RPS18(gene name)|psi-mi:RPS18(display_short)|uniprotkb:D6S218E(gene name synonym)|uniprotkb:Ke-3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS13(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155452|imex:IM-17331-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_072045.1|ensembl:ENSG00000096150(gene)|ensembl:ENSG00000223367(gene)|ensembl:ENSG00000226225(gene)|ensembl:ENSG00000231500(gene)|ensembl:ENSG00000235650(gene)|ensembl:ENST00000211372(transcript)|ensembl:ENST00000434122(transcript)|ensembl:ENST00000439602(transcript)|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENST00000454021(transcript)|ensembl:ENST00000457341(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001892(Ribosomal protein S13)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR018269|interpro:IPR027437|mint:P62269|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|dip:DIP-32892N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:yOHgKM/BuvgGdqp1OEVPeuiABg89606 intact-crc:3085053AB2F28C05|rigid:heL7zItAfEcdxAI8U0D1dXohfEg false mutation:220-220|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P12236 intact:EBI-6148200 intact:EBI-356254|ensembl:ENSP00000370808|uniprotkb:Q96C49 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155452|imex:IM-17331-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" ensembl:ENSG00000169100(gene)|ensembl:ENST00000381401(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|refseq:NP_001627.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606 intact-crc:3085053AB2F28C05|rigid:heL7zItAfEcdxAI8U0D1dXohfEg false mutation:220-220|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:Q9BUJ2 intact:EBI-6148200 intact:EBI-1018153|uniprotkb:O76022|uniprotkb:Q6ZSZ0|uniprotkb:Q7L8P4|uniprotkb:Q8N6Z4|uniprotkb:Q96G37|uniprotkb:Q9HAL3|uniprotkb:Q9UG75|intact:EBI-3183399|intact:EBI-2339292|uniprotkb:B3KMW7|ensembl:ENSP00000375863|intact:EBI-2563529 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:hnrl1_human(display_long)|uniprotkb:E1BAP5(gene name synonym)|uniprotkb:HNRNPUL1(gene name)|psi-mi:HNRNPUL1(display_short)|uniprotkb:HNRPUL1(gene name synonym)|uniprotkb:Adenovirus early region 1B-associated protein 5(gene name synonym)|uniprotkb:E1B-55 kDa-associated protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155452|imex:IM-17331-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_008971.2|refseq:NP_653333.1|go:"GO:0009615"(response to virus)|go:"GO:0019899"(enzyme binding)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027025|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q9BUJ2|reactome:R-HSA-72163|ensembl:ENSG00000105323(gene)|ensembl:ENST00000392006(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|refseq:NP_001308140.1|refseq:NP_001308137.1|dip:DIP-39419N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:IahA7SVR1NmvldrWKQlAwApinQE9606 intact-crc:3085053AB2F28C05|rigid:heL7zItAfEcdxAI8U0D1dXohfEg false mutation:220-220|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P07900 intact:EBI-6148200 intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|ensembl:ENSP00000216281|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155452|imex:IM-17331-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" go:"GO:0009409"(response to cold)|go:"GO:0016020"(membrane)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|ensembl:ENST00000216281(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000080824(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043335"(protein unfolding)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1UY8|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2BYH|rcsb pdb:2VCJ|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3B24|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5LO1|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6CYH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7LSZ|rcsb pdb:7LT0|reactome:R-HSA-1227986|reactome:R-HSA-1236382|rcsb pdb:6TN4|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9665233|reactome:R-HSA-9664565|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3K99|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:3T0H|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:4YKZ|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|refseq:NP_001017963.2|refseq:NP_005339.3|dip:DIP-27595N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606 intact-crc:3085053AB2F28C05|rigid:heL7zItAfEcdxAI8U0D1dXohfEg false mutation:220-220|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:O14734 intact:EBI-6148200 intact:EBI-1237371|uniprotkb:O15261|uniprotkb:Q17RX4|ensembl:ENSP00000217455 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:acot8_human(display_long)|uniprotkb:ACOT8(gene name)|psi-mi:ACOT8(display_short)|uniprotkb:ACTEIII(gene name synonym)|uniprotkb:PTE1(gene name synonym)|uniprotkb:Choloyl-coenzyme A thioesterase(gene name synonym)|uniprotkb:Peroxisomal acyl-coenzyme A thioester hydrolase 1(gene name synonym)|uniprotkb:Peroxisomal long-chain acyl-CoA thioesterase 1(gene name synonym)|uniprotkb:HIV-Nef-associated acyl-CoA thioesterase(gene name synonym)|uniprotkb:Thioesterase II(gene name synonym)|uniprotkb:Peroxisomal acyl-CoA thioesterase 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155452|imex:IM-17331-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_005460.2|dip:DIP-38179N|go:"GO:0036109"(alpha-linolenic acid metabolic process)|go:"GO:0043649"(dicarboxylic acid catabolic process)|go:"GO:0044466"(glutaryl-CoA hydrolase activity)|go:"GO:0045225"(negative regulation of CD4 production)|go:"GO:0047603"(acetoacetyl-CoA hydrolase activity)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0047994"(hydroxymethylglutaryl-CoA hydrolase activity)|go:"GO:0052689"(carboxylic ester hydrolase activity)|go:"GO:0052815"(medium-chain acyl-CoA hydrolase activity)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|interpro:IPR003703(Acyl-CoA thioesterase)|interpro:IPR029069|interpro:IPR042171|reactome:R-HSA-193368|reactome:R-HSA-2046106|reactome:R-HSA-389887|reactome:R-HSA-390247|reactome:R-HSA-9033241|ensembl:ENSG00000101473(gene)|ensembl:ENST00000217455(transcript)|go:"GO:0003986"(acetyl-CoA hydrolase activity)|go:"GO:0004778"(succinyl-CoA hydrolase activity)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0009062"(fatty acid catabolic process)|go:"GO:0016289"(CoA hydrolase activity)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0016559"(peroxisome fission)|go:"GO:0033540"(fatty acid beta-oxidation using acyl-CoA oxidase)|go:"GO:0033882"(choloyl-CoA hydrolase activity) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:Q8Y3l4ysgKPMi3mJU2/g8mVxWE09606 intact-crc:3085053AB2F28C05|rigid:heL7zItAfEcdxAI8U0D1dXohfEg false mutation:220-220|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:Q13162 intact:EBI-6148200 intact:EBI-2211957|uniprotkb:Q6FHT3|ensembl:ENSP00000368646 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:prdx4_human(display_long)|uniprotkb:PRDX4(gene name)|psi-mi:PRDX4(display_short)|uniprotkb:Peroxiredoxin IV(gene name synonym)|uniprotkb:Thioredoxin peroxidase AO372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase A0372(gene name synonym)|uniprotkb:Antioxidant enzyme AOE372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155452|imex:IM-17331-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_006397.1|ensembl:ENSG00000123131(gene)|ensembl:ENST00000379341(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000255"(negative regulation of male germ cell proliferation)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:Q13162|rcsb pdb:2PN8|rcsb pdb:3TJB|rcsb pdb:3TJF|rcsb pdb:3TJG|rcsb pdb:3TJJ|rcsb pdb:3TJK|rcsb pdb:3TKP|rcsb pdb:3TKQ|rcsb pdb:3TKR|rcsb pdb:3TKS|rcsb pdb:4RQX|rcsb pdb:5HQP|reactome:R-HSA-6798695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:5KWl3YuUpRDrSUxWlJS6sP7CLAs9606 intact-crc:3085053AB2F28C05|rigid:heL7zItAfEcdxAI8U0D1dXohfEg false mutation:220-220|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P23396 intact:EBI-6148200 intact:EBI-351193|uniprotkb:Q498B5|uniprotkb:Q8NI95|uniprotkb:B2R7N5|ensembl:ENSP00000433821|ensembl:ENSP00000434643|ensembl:ENSP00000436971|uniprotkb:J3KN86 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:rs3_human(display_long)|uniprotkb:RPS3(gene name)|psi-mi:RPS3(display_short)|uniprotkb:Small ribosomal subunit protein uS3(gene name synonym)|uniprotkb:OK/SW-cl.26(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155452|imex:IM-17331-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_000996.2|ensembl:ENSG00000149273(gene)|ensembl:ENST00000524851(transcript)|ensembl:ENST00000527446(transcript)|ensembl:ENST00000531188(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR004044(K Homology, type 2)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|go:"GO:0071159"(NF-kappaB complex)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR018280|interpro:IPR036419|mint:P23396|rcsb pdb:1WH9|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|rcsb pdb:6QZP|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|refseq:NP_001243731.1|refseq:NP_001247436.1|refseq:NP_001247435.1|dip:DIP-33177N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:fsDW18AMR3YyEEIhMVcngYRWkps9606 intact-crc:3085053AB2F28C05|rigid:heL7zItAfEcdxAI8U0D1dXohfEg false mutation:220-220|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P08238 intact:EBI-6148200 intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155452|imex:IM-17331-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:wOsW7C10v2oMsM+REE38K6PAan09606 intact-crc:3085053AB2F28C05|rigid:heL7zItAfEcdxAI8U0D1dXohfEg false mutation:220-220|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:Q5VTE0 intact:EBI-6148200 intact:EBI-877809 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:ef1a3_human(display_long)|uniprotkb:EEF1A1P5(gene name)|psi-mi:EEF1A1P5(display_short)|uniprotkb:Eukaryotic elongation factor 1 A-like 3(gene name synonym)|uniprotkb:EEF1AL3(gene name synonym)|uniprotkb:Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155452|imex:IM-17331-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR031157|reactome:R-HSA-156842|interpro:IPR027417 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:3t6tj3i+3CKTC1NsrHyBkeoRK789606 intact-crc:3085053AB2F28C05|rigid:heL7zItAfEcdxAI8U0D1dXohfEg false mutation:220-220|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P07437 intact:EBI-6148200 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155452|imex:IM-17331-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:3085053AB2F28C05|rigid:heL7zItAfEcdxAI8U0D1dXohfEg false mutation:220-220|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P68104 intact:EBI-6148200 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155452|imex:IM-17331-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 intact-crc:3085053AB2F28C05|rigid:heL7zItAfEcdxAI8U0D1dXohfEg false mutation:220-220|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P31943 intact:EBI-6148200 intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168|ensembl:ENSP00000377082|ensembl:ENSP00000397797|ensembl:ENSP00000492076|ensembl:ENSP00000495786 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155452|imex:IM-17331-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_005511.1|refseq:NP_001244222.1|ensembl:ENSG00000169045(gene)|ensembl:ENSG00000284254(gene)|ensembl:ENST00000356731(transcript)|ensembl:ENST00000393432(transcript)|ensembl:ENST00000442819(transcript)|ensembl:ENST00000638505(transcript)|ensembl:ENST00000643310(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606 intact-crc:3085053AB2F28C05|rigid:heL7zItAfEcdxAI8U0D1dXohfEg false mutation:220-220|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:Q06830 intact:EBI-6148200 intact:EBI-353193|ensembl:ENSP00000262746|ensembl:ENSP00000361152|ensembl:ENSP00000389047|ensembl:ENSP00000407034|ensembl:ENSP00000503140|uniprotkb:P35703|uniprotkb:Q2V576|uniprotkb:Q5T154|uniprotkb:Q5T155|uniprotkb:B5BU26|uniprotkb:D3DPZ8 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:prdx1_human(display_long)|uniprotkb:PRDX1(gene name)|psi-mi:PRDX1(display_short)|uniprotkb:PAGA(gene name synonym)|uniprotkb:PAGB(gene name synonym)|uniprotkb:TDPX2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Proliferation-associated gene protein(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor A(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155452|imex:IM-17331-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" ensembl:ENSG00000117450(gene)|ensembl:ENST00000262746(transcript)|ensembl:ENST00000319248(transcript)|ensembl:ENST00000424390(transcript)|ensembl:ENST00000447184(transcript)|ensembl:ENST00000676549(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003723"(RNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042470"(melanosome)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q06830|rcsb pdb:2RII|rcsb pdb:3HY2|rcsb pdb:4XCS|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803|refseq:NP_001189360.1|refseq:NP_002565.1|refseq:NP_859047.1|refseq:NP_859048.1|dip:DIP-33152N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:ZM5ZXF900izH81QVqgd2+opwMrs9606 intact-crc:3085053AB2F28C05|rigid:heL7zItAfEcdxAI8U0D1dXohfEg false mutation:220-220|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:Q6NSJ2 intact:EBI-6148200 intact:EBI-6148204|uniprotkb:Q8N7Z4|ensembl:ENSP00000292140 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:phlb3_human(display_long)|uniprotkb:PHLDB3(gene name)|psi-mi:PHLDB3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155452|imex:IM-17331-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_942147.3|ensembl:ENSG00000176531(gene)|ensembl:ENST00000292140(transcript)|go:"GO:0019899"(enzyme binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037810 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:mHR2QwOa65vWru5ZUAnRSjMU8lU9606 intact-crc:3085053AB2F28C05|rigid:heL7zItAfEcdxAI8U0D1dXohfEg false mutation:220-220|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04413 uniprotkb:P62249 intact:EBI-6148200 intact:EBI-352480|uniprotkb:P17008|uniprotkb:B2RDD5|ensembl:ENSP00000251453 psi-mi:us03_hhv11(display_long)|uniprotkb:US3(gene name)|psi-mi:US3(display_short) psi-mi:rs16_human(display_long)|uniprotkb:RPS16(gene name)|psi-mi:RPS16(display_short)|uniprotkb:Small ribosomal subunit protein uS9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155452|imex:IM-17331-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137138.1|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0005524"(ATP binding)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039525"(modulation by virus of host chromatin organization)|go:"GO:0039526"(modulation by virus of host apoptotic process)|go:"GO:0042025"(host cell nucleus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311" refseq:NP_001011.1|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000105193(gene)|ensembl:ENST00000251453(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097421"(liver regeneration)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR020574|mint:P62249|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|dip:DIP-33200N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PSN3xdFG9w1B8UGVYULnEZH4btY10299 rogid:OrKriR6HsATLaO+drdUa2w3Gpd09606 intact-crc:3085053AB2F28C05|rigid:heL7zItAfEcdxAI8U0D1dXohfEg false mutation:220-220|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q9Y265 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-353675|uniprotkb:P82276|uniprotkb:Q1KMR0|uniprotkb:Q53HK5|uniprotkb:Q53HL7|uniprotkb:Q53Y27|uniprotkb:Q9BSX9|uniprotkb:B2R5S0|ensembl:ENSP00000318297|ensembl:ENSP00000494621 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ruvb1_human(display_long)|uniprotkb:RUVBL1(gene name)|psi-mi:RUVBL1(display_short)|uniprotkb:NMP238(gene name synonym)|uniprotkb:TIP49(gene name synonym)|uniprotkb:TIP49A(gene name synonym)|uniprotkb:49 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49a(gene name synonym)|uniprotkb:Pontin 52(gene name synonym)|uniprotkb:Nuclear matrix protein 238(gene name synonym)|uniprotkb:54 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80H(gene name synonym)|uniprotkb:TIP60-associated protein 54-alpha(gene name synonym)|uniprotkb:INO80 complex subunit H(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155547|imex:IM-17331-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_003698.1|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:Q9Y265|rcsb pdb:2C9O|rcsb pdb:2XSZ|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|reactome:R-HSA-201722|reactome:R-HSA-3214847|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5696394|reactome:R-HSA-606279|ensembl:ENSG00000175792(gene)|ensembl:ENSG00000284901(gene)|ensembl:ENST00000322623(transcript)|ensembl:ENST00000643444(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|refseq:NP_001306013.1|dip:DIP-29937N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:+FA/xQTUldQoWGRgad9U8vZpTHw9606 intact-crc:63422C8B83652137|rigid:cfKubBUXQGZU+gJUzz1maWdCigo false tandem tag:?-?|mutation:41-42,38-38 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P27986 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-79464|intact:EBI-28974553|ensembl:ENSP00000428056|ensembl:ENSP00000429277|uniprotkb:Q15747|uniprotkb:Q4VBZ7|uniprotkb:Q53EM6|uniprotkb:Q8IXA2|uniprotkb:Q8N1C5|uniprotkb:D3DWA0|uniprotkb:B3KT19|uniprotkb:E7EX19 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:p85a_human(display_long)|uniprotkb:PIK3R1(gene name)|psi-mi:PIK3R1(display_short)|uniprotkb:GRB1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155547|imex:IM-17331-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001229395.1|refseq:NP_852556.2|refseq:NP_852664.1|refseq:NP_852665.1|ensembl:ENSG00000145675(gene)|ensembl:ENST00000521381(transcript)|ensembl:ENST00000521657(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|ensembl:ENST00000320694|ensembl:ENSP00000323512|ensembl:ENST00000336483|ensembl:ENSP00000338554|ensembl:ENSP00000428056|ensembl:ENSP00000429277|ensembl:ENST00000523872|ensembl:ENSP00000430098|rcsb pdb:5SXA|rcsb pdb:5SXB|rcsb pdb:5SXC|rcsb pdb:5SXD|rcsb pdb:5SXE|rcsb pdb:5SXF|rcsb pdb:5SXI|rcsb pdb:5SXJ|rcsb pdb:5SXK|rcsb pdb:5UBT|rcsb pdb:5UK8|rcsb pdb:5UKJ|rcsb pdb:5SX9|rcsb pdb:5UL1|rcsb pdb:5VLR|rcsb pdb:5XGH|rcsb pdb:5XGI|rcsb pdb:5XGJ|rcsb pdb:6NCT|rcsb pdb:6PYR|rcsb pdb:6PYU|reactome:R-HSA-1660499|rcsb pdb:7CIO|rcsb pdb:7LM2|reactome:R-HSA-180292|reactome:R-HSA-109704|reactome:R-HSA-1839117|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1236382|reactome:R-HSA-186763|reactome:R-HSA-1963642|reactome:R-HSA-1250342|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-198203|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-1433557|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-430116|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654689|reactome:R-HSA-5654695|reactome:R-HSA-5654710|reactome:R-HSA-5654720|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9603381|reactome:R-HSA-9607240|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-983695|reactome:R-HSA-5655253|reactome:R-HSA-5655302|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-6811558|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-5655291|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9027276|reactome:R-HSA-9028335|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0043559"(insulin binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1990578"(perinuclear endoplasmic reticulum membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035591|interpro:IPR036028|interpro:IPR036860|interpro:IPR044124|mint:P27986|rcsb pdb:1A0N|rcsb pdb:1AZG|rcsb pdb:1H9O|rcsb pdb:1PBW|rcsb pdb:1PHT|rcsb pdb:1PIC|rcsb pdb:1PKS|rcsb pdb:1PKT|rcsb pdb:2IUG|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|rcsb pdb:2IUH|rcsb pdb:2IUI|rcsb pdb:2RD0|rcsb pdb:3HHM|rcsb pdb:3HIZ|rcsb pdb:3I5R|rcsb pdb:3I5S|rcsb pdb:4A55|rcsb pdb:4JPS|rcsb pdb:4L1B|rcsb pdb:4L23|rcsb pdb:4L2Y|rcsb pdb:4OVU|rcsb pdb:4OVV|rcsb pdb:4WAF|rcsb pdb:4YKN|rcsb pdb:4ZOP|rcsb pdb:5AUL|rcsb pdb:5FI4|rcsb pdb:5GJI|rcsb pdb:5ITD|rcsb pdb:5M6U|rcsb pdb:5SW8|rcsb pdb:5SWG|rcsb pdb:5SWO|rcsb pdb:2V1Y|rcsb pdb:5SWP|rcsb pdb:5SWR|rcsb pdb:5SWT|rcsb pdb:5SX8|refseq:XP_016865074.1|refseq:XP_005248599.1|dip:DIP-119N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:pANLtVCSWVr64OXaS6bCjGBwfig9606 intact-crc:63422C8B83652137|rigid:cfKubBUXQGZU+gJUzz1maWdCigo false tandem tag:?-?|mutation:41-42,38-38 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P07437 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155547|imex:IM-17331-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:63422C8B83652137|rigid:cfKubBUXQGZU+gJUzz1maWdCigo false tandem tag:?-?|mutation:41-42,38-38 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:O00459 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-346930|uniprotkb:Q5EAT5|uniprotkb:Q9UPH9|intact:EBI-28974273|ensembl:ENSP00000222254 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:p85b_human(display_long)|uniprotkb:PIK3R2(gene name)|psi-mi:PIK3R2(display_short)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155547|imex:IM-17331-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSP00000222254|refseq:NP_005018.1|dip:DIP-31811N|ensembl:ENSG00000105647(gene)|ensembl:ENST00000222254(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|rcsb pdb:6OX7|rcsb pdb:6U28|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-186763|reactome:R-HSA-198203|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|mint:O00459|rcsb pdb:2KT1|rcsb pdb:2XS6|rcsb pdb:3MTT|rcsb pdb:3O5Z|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-210993|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9013409 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:Ij0WS0eKPwShgFWQc7OEss7AcAU9606 intact-crc:63422C8B83652137|rigid:cfKubBUXQGZU+gJUzz1maWdCigo false tandem tag:?-?|mutation:41-42,38-38 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P60660 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-300817|uniprotkb:P16475|uniprotkb:P24572|uniprotkb:P24573|uniprotkb:Q12790|ensembl:ENSP00000446955|ensembl:ENSP00000448101|uniprotkb:Q6IAZ0|uniprotkb:Q6IPY5|uniprotkb:Q561V9 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:myl6_human(display_long)|uniprotkb:MYL6(gene name)|psi-mi:MYL6(display_short)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6(gene name synonym)|uniprotkb:Myosin light chain alkali 3(gene name synonym)|uniprotkb:Myosin light chain 3(gene name synonym)|uniprotkb:17 kDa myosin light chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155547|imex:IM-17331-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000092841(gene)|ensembl:ENST00000548293(transcript)|ensembl:ENST00000550697(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016020"(membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P60660|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:NP_066299.2|refseq:NP_524147.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:LhE3NUqcuHlOla13C0vjnFZfzy89606 intact-crc:63422C8B83652137|rigid:cfKubBUXQGZU+gJUzz1maWdCigo false tandem tag:?-?|mutation:41-42,38-38 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P23528 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352733|uniprotkb:Q53Y87|uniprotkb:Q9UCA2|uniprotkb:B3KUQ1|ensembl:ENSP00000309629|ensembl:ENSP00000432660 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:cof1_human(display_long)|uniprotkb:CFL1(gene name)|psi-mi:CFL1(display_short)|uniprotkb:CFL(gene name synonym)|uniprotkb:Cofilin, non-muscle isoform(gene name synonym)|uniprotkb:18 kDa phosphoprotein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155547|imex:IM-17331-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_005498.1|ensembl:ENSG00000172757(gene)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR027234|interpro:IPR029006|mint:P23528|rcsb pdb:1Q8G|rcsb pdb:1Q8X|rcsb pdb:3J0S|rcsb pdb:4BEX|rcsb pdb:5HVK|rcsb pdb:5L6W|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|reactome:R-HSA-114608|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-399954|reactome:R-HSA-5627117|reactome:R-HSA-8950505|ensembl:ENST00000308162(transcript)|ensembl:ENST00000525451(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009615"(response to virus)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0031258"(lamellipodium membrane)|dip:DIP-33000N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:wgBEUL55sE9G9Be1f/A1OA6KRb49606 intact-crc:63422C8B83652137|rigid:cfKubBUXQGZU+gJUzz1maWdCigo false tandem tag:?-?|mutation:41-42,38-38 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P42338 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-2609540|uniprotkb:D3DNF0|uniprotkb:Q24JU2|ensembl:ENSP00000289153|ensembl:ENSP00000418143|ensembl:ENSP00000501150 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pk3cb_human(display_long)|uniprotkb:PIK3CB(gene name)|psi-mi:PIK3CB(display_short)|uniprotkb:PIK3C1(gene name synonym)|uniprotkb:Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155547|imex:IM-17331-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_006210.1|refseq:XP_011511197.1|refseq:XP_005247587.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0030168"(platelet activation)|go:"GO:0030496"(midbody)|go:"GO:0033031"(positive regulation of neutrophil apoptotic process)|go:"GO:0035004"(phosphatidylinositol 3-kinase activity)|go:"GO:0035005"(1-phosphatidylinositol-4-phosphate 3-kinase activity)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046934"(phosphatidylinositol-4,5-bisphosphate 3-kinase activity)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0070527"(platelet aggregation)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR000341(Phosphoinositide 3-kinase, ras-binding)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR003113(Phosphatidylinositol 3-kinase, p85-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR029071|interpro:IPR035892|interpro:IPR036940|interpro:IPR037702|interpro:IPR042236|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1660499|reactome:R-HSA-186763|reactome:R-HSA-198203|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8853659|reactome:R-HSA-9027276|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9673767|reactome:R-HSA-9673770|ensembl:ENSG00000051382(gene)|ensembl:ENST00000289153(transcript)|ensembl:ENST00000477593(transcript)|ensembl:ENST00000674063(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001952"(regulation of cell-matrix adhesion)|go:"GO:0002931"(response to ischemia)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_006713722.1|refseq:XP_016862108.1|dip:DIP-44775N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:Nga6TlSCXWs2NVRR5XfxvnLfWUk9606 intact-crc:63422C8B83652137|rigid:cfKubBUXQGZU+gJUzz1maWdCigo false tandem tag:?-?|mutation:41-42,38-38 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q562R1 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1773495|uniprotkb:Q562R2|uniprotkb:Q562S9|uniprotkb:Q562X8|uniprotkb:B2RPJ1|ensembl:ENSP00000416706 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:actbl_human(display_long)|uniprotkb:ACTBL2(gene name)|psi-mi:ACTBL2(display_short)|uniprotkb:Kappa-actin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155547|imex:IM-17331-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001017992.1|ensembl:ENSG00000169067(gene)|ensembl:ENST00000423391(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0007409"(axonogenesis)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0045202"(synapse)|go:"GO:0048870"(cell motility)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:Q562R1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:GTzKP5YRJGH8ocAJW0WEsdQFEdc9606 intact-crc:63422C8B83652137|rigid:cfKubBUXQGZU+gJUzz1maWdCigo false tandem tag:?-?|mutation:41-42,38-38 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q9Y2I1 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-2688731|uniprotkb:Q6PIB4|uniprotkb:Q9UEU4|uniprotkb:Q7L8M3|uniprotkb:Q6PGP3|uniprotkb:Q9UFW3|uniprotkb:Q7Z2X6|uniprotkb:Q9UES6|uniprotkb:C9J245|ensembl:ENSP00000339958|ensembl:ENSP00000418232 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:nisch_human(display_long)|uniprotkb:IRAS(gene name synonym)|uniprotkb:KIAA0975(gene name synonym)|uniprotkb:Imidazoline receptor 1(gene name synonym)|uniprotkb:Imidazoline receptor antisera-selected protein(gene name synonym)|uniprotkb:Imidazoline-1 receptor(gene name synonym)|uniprotkb:Imidazoline-1 receptor candidate protein(gene name synonym)|uniprotkb:NISCH(gene name)|psi-mi:NISCH(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155547|imex:IM-17331-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_009115.2|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048243"(norepinephrine secretion)|go:"GO:0055037"(recycling endosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001683(Phox-like)|interpro:IPR032675|interpro:IPR036871|interpro:IPR037904|mint:Q9Y2I1|rcsb pdb:3P0C|reactome:R-HSA-9013149|reactome:R-HSA-9696264|reactome:R-HSA-9696270|ensembl:ENSG00000010322(gene)|ensembl:ENST00000345716(transcript)|ensembl:ENST00000479054(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032228"(regulation of synaptic transmission, GABAergic)|refseq:NP_001263222.1|refseq:NP_001263223.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:GuBgG6MUrD5p1hIhGGmrtCjT0jQ9606 intact-crc:63422C8B83652137|rigid:cfKubBUXQGZU+gJUzz1maWdCigo false tandem tag:?-?|mutation:41-42,38-38 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P42336 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-2116585|uniprotkb:Q14CW1|uniprotkb:Q99762|ensembl:ENSP00000263967 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pk3ca_human(display_long)|uniprotkb:Phosphoinositide-3-kinase catalytic alpha polypeptide(gene name synonym)|uniprotkb:Serine/threonine protein kinase PIK3CA(gene name synonym)|uniprotkb:PIK3CA(gene name)|psi-mi:PIK3CA(display_short)|uniprotkb:Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha(gene name synonym)|uniprotkb:Phosphoinositide 3-kinase alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155547|imex:IM-17331-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:XP_011511196.1|refseq:XP_006713721.1|refseq:NP_006209.2|dip:DIP-42728N|ensembl:ENSG00000121879(gene)|ensembl:ENST00000263967(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001944"(vasculature development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0005944"(phosphatidylinositol 3-kinase complex, class IB)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006909"(phagocytosis)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030168"(platelet activation)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035004"(phosphatidylinositol 3-kinase activity)|go:"GO:0035005"(1-phosphatidylinositol-4-phosphate 3-kinase activity)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0038028"(insulin receptor signaling pathway via phosphatidylinositol 3-kinase)|go:"GO:0038084"(vascular endothelial growth factor signaling pathway)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0043276"(anoikis)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044029"(hypomethylation of CpG island)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046934"(phosphatidylinositol-4,5-bisphosphate 3-kinase activity)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110053"(regulation of actin filament organization)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR000341(Phosphoinositide 3-kinase, ras-binding)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR003113(Phosphatidylinositol 3-kinase, p85-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR029071|interpro:IPR035892|interpro:IPR036940|interpro:IPR037704|interpro:IPR042236|mint:P42336|rcsb pdb:2ENQ|rcsb pdb:2RD0|rcsb pdb:3HHM|rcsb pdb:3HIZ|rcsb pdb:3ZIM|rcsb pdb:4JPS|rcsb pdb:4L1B|rcsb pdb:4L23|rcsb pdb:4L2Y|rcsb pdb:4OVU|rcsb pdb:4OVV|rcsb pdb:4TUU|rcsb pdb:4TV3|rcsb pdb:4WAF|rcsb pdb:4YKN|rcsb pdb:4ZOP|rcsb pdb:5DXT|rcsb pdb:5FI4|rcsb pdb:5ITD|rcsb pdb:5SW8|rcsb pdb:5SWG|rcsb pdb:5SWO|rcsb pdb:5SWP|rcsb pdb:5SWR|rcsb pdb:5SWT|rcsb pdb:5SX8|rcsb pdb:5SX9|rcsb pdb:5SXA|rcsb pdb:5SXB|rcsb pdb:5SXC|rcsb pdb:5SXD|rcsb pdb:5SXE|rcsb pdb:5SXF|rcsb pdb:5SXI|rcsb pdb:5SXJ|rcsb pdb:5SXK|rcsb pdb:5UBR|rcsb pdb:5UK8|rcsb pdb:5UKJ|rcsb pdb:5UL1|rcsb pdb:5XGH|rcsb pdb:5XGI|rcsb pdb:5XGJ|rcsb pdb:6GVF|rcsb pdb:6GVG|rcsb pdb:6GVH|rcsb pdb:6GVI|rcsb pdb:6NCT|rcsb pdb:6OAC|rcsb pdb:6PYS|rcsb pdb:6VO7|rcsb pdb:7JIU|rcsb pdb:7K6M|rcsb pdb:7K6N|rcsb pdb:7K6O|rcsb pdb:7K71|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1236382|reactome:R-HSA-1250342|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-180292|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-1963642|reactome:R-HSA-198203|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654689|reactome:R-HSA-5654695|reactome:R-HSA-5654710|reactome:R-HSA-5654720|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-9009391|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9027276|reactome:R-HSA-9028335|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9603381|reactome:R-HSA-9607240|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|rcsb pdb:5DXH|reactome:R-HSA-9703465|reactome:R-HSA-9703648 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:YIZWt9VfCmyBCWYkqAEaMAEsl3w9606 intact-crc:63422C8B83652137|rigid:cfKubBUXQGZU+gJUzz1maWdCigo false tandem tag:?-?|mutation:41-42,38-38 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q92569 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-79893|intact:EBI-28975437|ensembl:ENSP00000262741|ensembl:ENSP00000361075|ensembl:ENSP00000412546|uniprotkb:O60482|uniprotkb:Q5T4P2|uniprotkb:B2R9C1|uniprotkb:Q5T4P1|uniprotkb:D3DQ12 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:p55g_human(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma(gene name synonym)|uniprotkb:PIK3R3(gene name)|psi-mi:PIK3R3(display_short)|uniprotkb:p55PIK(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155547|imex:IM-17331-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9670439|ensembl:ENSG00000117461(gene)|ensembl:ENST00000262741(transcript)|ensembl:ENST00000372006(transcript)|ensembl:ENST00000420542(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|interpro:IPR000980(SH2 motif)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR036860|mint:Q92569|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-2219530|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-512988|reactome:R-HSA-6811558|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|reactome:R-HSA-8853659|reactome:R-HSA-9009391|refseq:NP_001107644.1|refseq:NP_003620.3|ensembl:ENSP00000262741|ensembl:ENSP00000361075|ensembl:ENSP00000412546|ensembl:ENST00000423209|ensembl:ENSP00000391431|dip:DIP-30925N|refseq:NP_001290358.1|refseq:XP_016858103.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:oIVTuGRhg/Kn3h+Br1EfiAtiAQQ9606 intact-crc:63422C8B83652137|rigid:cfKubBUXQGZU+gJUzz1maWdCigo false tandem tag:?-?|mutation:41-42,38-38 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q9NNW5 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1568315|uniprotkb:B4DHK2|uniprotkb:Q3MIT1|uniprotkb:Q9UF63|ensembl:ENSP00000477389 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:wdr6_human(display_long)|uniprotkb:WDR6(gene name)|psi-mi:WDR6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155547|imex:IM-17331-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_060501.3|refseq:NP_001307475.1|refseq:NP_001307476.1|ensembl:ENSG00000178252(gene)|ensembl:ENST00000608424(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0030488"(tRNA methylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9NNW5|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:gYSDkyuDdKhj387/1P3bhpKJXy89606 intact-crc:63422C8B83652137|rigid:cfKubBUXQGZU+gJUzz1maWdCigo false tandem tag:?-?|mutation:41-42,38-38 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:O14654 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-356594|ensembl:ENSP00000505547 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155547|imex:IM-17331-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606 intact-crc:63422C8B83652137|rigid:cfKubBUXQGZU+gJUzz1maWdCigo false tandem tag:?-?|mutation:41-42,38-38 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P68371 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155547|imex:IM-17331-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606 intact-crc:63422C8B83652137|rigid:cfKubBUXQGZU+gJUzz1maWdCigo false tandem tag:?-?|mutation:41-42,38-38 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P62158 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155547|imex:IM-17331-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606 intact-crc:63422C8B83652137|rigid:cfKubBUXQGZU+gJUzz1maWdCigo false tandem tag:?-?|mutation:41-42,38-38 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q9Y230 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352939|ensembl:ENSP00000473172|uniprotkb:Q6FIB9|uniprotkb:Q6PK27|uniprotkb:Q9Y361|uniprotkb:B3KQ59|uniprotkb:E7ETE5|intact:EBI-1058527 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ruvb2_human(display_long)|uniprotkb:RUVBL2(gene name)|psi-mi:RUVBL2(display_short)|uniprotkb:TIP48(gene name synonym)|uniprotkb:TIP49B(gene name synonym)|uniprotkb:CGI-46(orf name)|uniprotkb:48 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49b(gene name synonym)|uniprotkb:Repressing pontin 52(gene name synonym)|uniprotkb:51 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80J(gene name synonym)|uniprotkb:TIP60-associated protein 54-beta(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155547|imex:IM-17331-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487|mint:Q9Y230|rcsb pdb:2CQA|rcsb pdb:2XSZ|rcsb pdb:3UK6|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6H7X|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|go:"GO:0140585"(promoter-enhancer loop anchoring activity)|reactome:R-HSA-3214847|ensembl:ENSG00000183207(gene)|ensembl:ENST00000595090(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000791"(euchromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006457"(protein folding)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0016573"(histone acetylation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|refseq:NP_006657.1|refseq:XP_011524632.1|refseq:NP_001308120.1|dip:DIP-28153N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:APKAWLDCJVULUP3nzqIaSLHKVN49606 intact-crc:63422C8B83652137|rigid:cfKubBUXQGZU+gJUzz1maWdCigo false tandem tag:?-?|mutation:41-42,38-38 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P35580 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-351758|intact:EBI-7850240|intact:MINT-8330016|uniprotkb:B2RWP9|uniprotkb:D3DTS1|uniprotkb:Q9BWG0|uniprotkb:Q12989|uniprotkb:Q16087|uniprotkb:Q149N3|ensembl:ENSP00000269243|uniprotkb:Q149N4|uniprotkb:Q6PK16|uniprotkb:F8VTL3|uniprotkb:Q4LE45 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:myh10_human(display_long)|uniprotkb:MYH10(gene name)|psi-mi:MYH10(display_short)|uniprotkb:Myosin heavy chain 10(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIb(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIb(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type B(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155547|imex:IM-17331-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001243024.1|refseq:NP_001242941.1|refseq:NP_005955.3|ensembl:ENSG00000133026(gene)|ensembl:ENST00000269243(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016459"(myosin complex)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042641"(actomyosin)|go:"GO:0043531"(ADP binding)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097513"(myosin II filament)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:P35580|rcsb pdb:4PD3|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:XP_016880169.1|refseq:XP_016880170.1|refseq:XP_016880171.1|dip:DIP-31110N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:iSHfJZbrWg1L+vSpu1n7RmTTNN49606 intact-crc:63422C8B83652137|rigid:cfKubBUXQGZU+gJUzz1maWdCigo false tandem tag:?-?|mutation:41-42,38-38 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5U8Y3 uniprotkb:Q15370 intact:EBI-6148505 intact:EBI-301238|ensembl:ENSP00000386652|uniprotkb:B7WPD3 psi-mi:q5u8y3_9flav(display_long) psi-mi:elob_human(display_long)|uniprotkb:ELOB(gene name)|psi-mi:ELOB(display_short)|uniprotkb:Elongin 18 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit B(gene name synonym)|uniprotkb:SIII p18(gene name synonym)|uniprotkb:TCEB2(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155606|imex:IM-17331-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR042542|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity) ensembl:ENSG00000103363(gene)|ensembl:ENST00000409906(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039049|mint:Q15370|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2JZ3|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:4WQO|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:6SIS|refseq:NP_009039.1|refseq:NP_996896.1|dip:DIP-29570N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:JzxhcKIvkUc0pqbthycrQOflfEw11096 rogid:apX4QFpDC4Dz3MAs7tQ8+XFHx6I9606 intact-crc:7B993C5EA7369E40|rigid:qMTzc/vuiApjfntUrHjGbiothyc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5U8Y3 uniprotkb:Q9BRZ2 intact:EBI-6148505 intact:EBI-1048636|uniprotkb:Q6PJS5|uniprotkb:Q86VT6|uniprotkb:Q8N2H8|uniprotkb:Q8NAC0|uniprotkb:Q9H031|intact:EBI-2129929|ensembl:ENSP00000305161 psi-mi:q5u8y3_9flav(display_long) psi-mi:tri56_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase TRIM56(gene name synonym)|uniprotkb:RING finger protein 109(gene name synonym)|uniprotkb:TRIM56(gene name)|psi-mi:TRIM56(display_short)|uniprotkb:RNF109(gene name synonym)|uniprotkb:Tripartite motif-containing protein 56(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155606|imex:IM-17331-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR042542|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity) refseq:NP_112223.1|refseq:XP_011514891.1|ensembl:ENSG00000169871(gene)|ensembl:ENST00000306085(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034340"(response to type I interferon)|go:"GO:0045087"(innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|rcsb pdb:5JW7|reactome:R-HSA-3134975 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:JzxhcKIvkUc0pqbthycrQOflfEw11096 rogid:ezli6d8R3mc5aNovKvPv2ayypbE9606 intact-crc:7B993C5EA7369E40|rigid:qMTzc/vuiApjfntUrHjGbiothyc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5U8Y3 uniprotkb:A7E2V4 intact:EBI-6148505 intact:EBI-947995|uniprotkb:Q17RS8|uniprotkb:Q2TAB8|uniprotkb:Q6P439|uniprotkb:Q8IW81|uniprotkb:Q8NB34|uniprotkb:Q9H8F3|uniprotkb:O94987|uniprotkb:B2RP37|ensembl:ENSP00000474748 psi-mi:q5u8y3_9flav(display_long) psi-mi:zswm8_human(display_long)|uniprotkb:ZSWIM8(gene name)|psi-mi:ZSWIM8(display_short)|uniprotkb:KIAA0913(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11096(classical swine fever virus)|taxid:11096(Classical swine fever virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155606|imex:IM-17331-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008751(Peptidase C53, pestivirus Npro)|interpro:IPR042542|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity) refseq:NP_001229416.1|refseq:NP_001229417.1|refseq:NP_055852.2|refseq:XP_006717788.1|ensembl:ENSG00000214655(gene)|ensembl:ENST00000605216(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1902667"(regulation of axon guidance)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|go:"GO:2000627"(positive regulation of miRNA catabolic process)|interpro:IPR007527(Zinc finger, SWIM-type)|reactome:R-HSA-9010553 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:JzxhcKIvkUc0pqbthycrQOflfEw11096 rogid:L/Zc7H24cEC7qtYp34nahN0pKEc9606 intact-crc:7B993C5EA7369E40|rigid:qMTzc/vuiApjfntUrHjGbiothyc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMB5 uniprotkb:P42224 intact:EBI-6148584 intact:EBI-1057697|uniprotkb:Q53S88|uniprotkb:Q53XW4|uniprotkb:B2RCA0|uniprotkb:Q9UDL5|uniprotkb:A8K989|uniprotkb:D2KFR8|uniprotkb:Q68D00|uniprotkb:D3DPI7|ensembl:ENSP00000354394|ensembl:ENSP00000386244|ensembl:ENSP00000388240|ensembl:ENSP00000438703 psi-mi:ncap_measc(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:NP(gene name synonym)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:stat1_human(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)|uniprotkb:Transcription factor ISGF-3 components p91/p84(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:645098(measc)|taxid:645098("measles virus (strai") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155675|imex:IM-17331-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002021(Paramyxovirus nucleocapsid protein)|refseq:NP_056918.1|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0030430"(host cell cytoplasm) refseq:NP_009330.1|refseq:NP_644671.1|rcsb pdb:1YVL|rcsb pdb:2KA6|rcsb pdb:3WWT|reactome:R-HSA-1059683|reactome:R-HSA-1169408|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8939902|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9013508|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-909733|rcsb pdb:1BF5|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-912694|refseq:XP_006712781.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016922"(nuclear receptor binding)|ensembl:ENSG00000115415(gene)|ensembl:ENST00000361099(transcript)|ensembl:ENST00000409465(transcript)|ensembl:ENST00000415035(transcript)|ensembl:ENST00000540176(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051607"(defense response to virus)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0061326"(renal tubule development)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022752|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|interpro:IPR035859|interpro:IPR036535|interpro:IPR036860|interpro:IPR038295|mint:P42224|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042393"(histone binding)|dip:DIP-46140N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:t7kjbgqq+Vwy1Yu76EZZmPYhENg645098 rogid:a2ZnhdFZkctbjaXLpsYNJ3q5Cv49606 intact-crc:803C722753C7CB3E|rigid:m48CD8Lb9Iljb0WpLtyKVj4J+wM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMB5 uniprotkb:Q9BQE3 intact:EBI-6148584 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:ncap_measc(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:NP(gene name synonym)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:645098(measc)|taxid:645098("measles virus (strai") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155675|imex:IM-17331-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002021(Paramyxovirus nucleocapsid protein)|refseq:NP_056918.1|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0030430"(host cell cytoplasm) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:t7kjbgqq+Vwy1Yu76EZZmPYhENg645098 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:803C722753C7CB3E|rigid:m48CD8Lb9Iljb0WpLtyKVj4J+wM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMB5 uniprotkb:Q15172 intact:EBI-6148584 intact:EBI-641666|uniprotkb:Q2NL72|uniprotkb:Q5VVB2|uniprotkb:Q8TBI9|uniprotkb:B2R6D2|uniprotkb:D3DT99|uniprotkb:B7Z7L2|ensembl:ENSP00000261461 psi-mi:ncap_measc(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:NP(gene name synonym)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:2a5a_human(display_long)|uniprotkb:PP2A B subunit isoform B'-alpha(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-alpha(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-alpha(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-alpha(gene name synonym)|uniprotkb:PPP2R5A(gene name)|psi-mi:PPP2R5A(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:645098(measc)|taxid:645098("measles virus (strai") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155675|imex:IM-17331-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002021(Paramyxovirus nucleocapsid protein)|refseq:NP_056918.1|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0030430"(host cell cytoplasm) refseq:NP_001186685.1|refseq:NP_006234.1|dip:DIP-459N|reactome:R-HSA-9648025|reactome:R-HSA-68877|ensembl:ENSG00000066027(gene)|ensembl:ENST00000261461(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0031430"(M band)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0090219"(negative regulation of lipid kinase activity)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q15172|rcsb pdb:6NTS|reactome:R-HSA-141444|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-5675221|reactome:R-HSA-6811558 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:t7kjbgqq+Vwy1Yu76EZZmPYhENg645098 rogid:DpFpGFjwzJej//cr7ciShgzJpCE9606 intact-crc:803C722753C7CB3E|rigid:m48CD8Lb9Iljb0WpLtyKVj4J+wM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMB5 uniprotkb:P67775 intact:EBI-6148584 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:ncap_measc(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:NP(gene name synonym)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:645098(measc)|taxid:645098("measles virus (strai") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155675|imex:IM-17331-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002021(Paramyxovirus nucleocapsid protein)|refseq:NP_056918.1|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0030430"(host cell cytoplasm) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:t7kjbgqq+Vwy1Yu76EZZmPYhENg645098 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 intact-crc:803C722753C7CB3E|rigid:m48CD8Lb9Iljb0WpLtyKVj4J+wM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMB5 uniprotkb:Q13362 intact:EBI-6148584 intact:EBI-1266156|uniprotkb:B4DYJ8|uniprotkb:F5GWP3|uniprotkb:Q14391|uniprotkb:Q15060|uniprotkb:Q15174|uniprotkb:B5BUA5|intact:EBI-2556020|uniprotkb:Q6ZN33|ensembl:ENSP00000333905 psi-mi:ncap_measc(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:NP(gene name synonym)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:2a5g_human(display_long)|uniprotkb:PPP2R5C(gene name)|psi-mi:PPP2R5C(display_short)|uniprotkb:KIAA0044(gene name synonym)|uniprotkb:PP2A B subunit isoform B'-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-gamma(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-29(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:645098(measc)|taxid:645098("measles virus (strai") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155675|imex:IM-17331-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002021(Paramyxovirus nucleocapsid protein)|refseq:NP_056918.1|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0030430"(host cell cytoplasm) refseq:NP_002710.2|refseq:NP_848701.1|refseq:NP_848702.1|refseq:NP_001155197.1|refseq:NP_001155198.1|refseq:XP_011535222.1|refseq:XP_005267884.1|dip:DIP-39401N|ensembl:ENSG00000078304(gene)|ensembl:ENST00000334743(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q13362|rcsb pdb:2IAE|rcsb pdb:2JAK|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3FGA|rcsb pdb:5JJA|rcsb pdb:5K6S|rcsb pdb:5SW9|rcsb pdb:5SWF|rcsb pdb:6OYL|rcsb pdb:6TOQ|rcsb pdb:6VOY|rcsb pdb:6VRO|rcsb pdb:6Z2Y|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-141444|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:t7kjbgqq+Vwy1Yu76EZZmPYhENg645098 rogid:vKPPLnEfyCzEZ2O5lrQDCRghiV09606 intact-crc:803C722753C7CB3E|rigid:m48CD8Lb9Iljb0WpLtyKVj4J+wM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMB5 uniprotkb:Q71U36 intact:EBI-6148584 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:ncap_measc(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:NP(gene name synonym)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:645098(measc)|taxid:645098("measles virus (strai") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155675|imex:IM-17331-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002021(Paramyxovirus nucleocapsid protein)|refseq:NP_056918.1|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0030430"(host cell cytoplasm) refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:t7kjbgqq+Vwy1Yu76EZZmPYhENg645098 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 intact-crc:803C722753C7CB3E|rigid:m48CD8Lb9Iljb0WpLtyKVj4J+wM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMB5 uniprotkb:Q14738 intact:EBI-6148584 intact:EBI-396563|uniprotkb:O00494|uniprotkb:O00696|uniprotkb:Q15171|uniprotkb:Q5TC39|uniprotkb:B5BUA6|uniprotkb:A8K3I9|ensembl:ENSP00000417963 psi-mi:ncap_measc(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:NP(gene name synonym)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:2a5d_human(display_long)|uniprotkb:PPP2R5D(gene name)|psi-mi:PPP2R5D(display_short)|uniprotkb:PP2A B subunit isoform B'-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-delta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:645098(measc)|taxid:645098("measles virus (strai") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155675|imex:IM-17331-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002021(Paramyxovirus nucleocapsid protein)|refseq:NP_056918.1|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0030430"(host cell cytoplasm) refseq:NP_006236.1|refseq:NP_851307.1|refseq:NP_851308.1|ensembl:ENSG00000112640(gene)|ensembl:ENST00000485511(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q14738|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9634600|reactome:R-HSA-9648025|refseq:NP_001257405.1|dip:DIP-29961N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:t7kjbgqq+Vwy1Yu76EZZmPYhENg645098 rogid:tQnhuUL/6Iuhcyu/B41Me1LWpr89606 intact-crc:803C722753C7CB3E|rigid:m48CD8Lb9Iljb0WpLtyKVj4J+wM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMB5 uniprotkb:Q9BYX4 intact:EBI-6148584 intact:EBI-6115771|uniprotkb:Q2NKL6|uniprotkb:Q6DC96|uniprotkb:Q86X56|uniprotkb:Q96MX8|uniprotkb:Q9H3G6|ensembl:ENSP00000497271 psi-mi:ncap_measc(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:NP(gene name synonym)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:ifih1_human(display_long)|uniprotkb:Helicase with 2 CARD domains(gene name synonym)|uniprotkb:Interferon-induced with helicase C domain protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 5(gene name synonym)|uniprotkb:Murabutide down-regulated protein(gene name synonym)|uniprotkb:RNA helicase-DEAD box protein 116(gene name synonym)|uniprotkb:RIG-I-like receptor 2(gene name synonym)|uniprotkb:IFIH1(gene name)|psi-mi:IFIH1(display_short)|uniprotkb:MDA5(gene name synonym)|uniprotkb:RH116(gene name synonym)|uniprotkb:Clinically amyopathic dermatomyositis autoantigen 140 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:645098(measc)|taxid:645098("measles virus (strai") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155675|imex:IM-17331-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002021(Paramyxovirus nucleocapsid protein)|refseq:NP_056918.1|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0030430"(host cell cytoplasm) refseq:NP_071451.2|dip:DIP-42607N|ensembl:ENSG00000115267(gene)|ensembl:ENST00000649979(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009597"(detection of virus)|go:"GO:0009615"(response to virus)|go:"GO:0016925"(protein sumoylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034344"(regulation of type III interferon production)|go:"GO:0039528"(cytoplasmic pattern recognition receptor signaling pathway in response to virus)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR011029(DEATH-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021673|interpro:IPR027417|interpro:IPR031964|interpro:IPR038557|interpro:IPR041204|rcsb pdb:2RQB|rcsb pdb:3B6E|rcsb pdb:3GA3|rcsb pdb:4GL2|rcsb pdb:7JL0|rcsb pdb:7JL2|reactome:R-HSA-168928|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:t7kjbgqq+Vwy1Yu76EZZmPYhENg645098 rogid:d+r0DiHIxi32jKF7uOTENK3r/qQ9606 intact-crc:803C722753C7CB3E|rigid:m48CD8Lb9Iljb0WpLtyKVj4J+wM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMB5 uniprotkb:P30153 intact:EBI-6148584 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:ncap_measc(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:NP(gene name synonym)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:645098(measc)|taxid:645098("measles virus (strai") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155675|imex:IM-17331-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002021(Paramyxovirus nucleocapsid protein)|refseq:NP_056918.1|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0030430"(host cell cytoplasm) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:t7kjbgqq+Vwy1Yu76EZZmPYhENg645098 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:803C722753C7CB3E|rigid:m48CD8Lb9Iljb0WpLtyKVj4J+wM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMB5 uniprotkb:P52630 intact:EBI-6148584 intact:EBI-1546963|uniprotkb:Q16430|uniprotkb:Q16431|uniprotkb:Q9UDL4|intact:EBI-10989287|uniprotkb:B4DLC7|uniprotkb:G3V2M6|ensembl:ENSP00000315768 psi-mi:ncap_measc(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:NP(gene name synonym)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:stat2_human(display_long)|uniprotkb:p113(gene name synonym)|uniprotkb:STAT2(gene name)|psi-mi:STAT2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:645098(measc)|taxid:645098("measles virus (strai") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155675|imex:IM-17331-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002021(Paramyxovirus nucleocapsid protein)|refseq:NP_056918.1|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0030430"(host cell cytoplasm) refseq:NP_005410.1|refseq:NP_938146.1|dip:DIP-38511N|ensembl:ENSG00000170581(gene)|ensembl:ENST00000314128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0090140"(regulation of mitochondrial fission)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022756|interpro:IPR035854|interpro:IPR036535|interpro:IPR036860|mint:P52630|rcsb pdb:2KA4|rcsb pdb:6UX2|rcsb pdb:6WCZ|reactome:R-HSA-8854691|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9679191 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:t7kjbgqq+Vwy1Yu76EZZmPYhENg645098 rogid:uA0lxm5vmrLClQRP7NItd0/u4Ko9606 intact-crc:803C722753C7CB3E|rigid:m48CD8Lb9Iljb0WpLtyKVj4J+wM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMB5 uniprotkb:Q16537 intact:EBI-6148584 intact:EBI-968374|uniprotkb:B7ZAW5|uniprotkb:J3KQN6|ensembl:ENSP00000337641|uniprotkb:Q52LW4|uniprotkb:A4FU37|uniprotkb:B7ZKK8|intact:EBI-10962508|uniprotkb:B7ZKK9 psi-mi:ncap_measc(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:NP(gene name synonym)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:2a5e_human(display_long)|uniprotkb:PPP2R5E(gene name)|psi-mi:PPP2R5E(display_short)|uniprotkb:PP2A B subunit isoform B'-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:645098(measc)|taxid:645098("measles virus (strai") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155675|imex:IM-17331-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002021(Paramyxovirus nucleocapsid protein)|refseq:NP_056918.1|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0030430"(host cell cytoplasm) ensembl:ENSG00000154001(gene)|ensembl:ENST00000337537(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR016024(Armadillo-type fold)|mint:Q16537|reactome:R-HSA-141444|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025|interpro:IPR011989(Armadillo-like helical)|refseq:NP_006237.1|refseq:NP_001269108.1|refseq:NP_001269109.1|refseq:NP_001269110.1|refseq:NP_001269111.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:t7kjbgqq+Vwy1Yu76EZZmPYhENg645098 rogid:m6vjnzx9eg+HpXrI2KKBLPbObzA9606 intact-crc:803C722753C7CB3E|rigid:m48CD8Lb9Iljb0WpLtyKVj4J+wM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMB5 uniprotkb:P07437 intact:EBI-6148584 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:ncap_measc(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:NP(gene name synonym)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:645098(measc)|taxid:645098("measles virus (strai") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155675|imex:IM-17331-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002021(Paramyxovirus nucleocapsid protein)|refseq:NP_056918.1|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0030430"(host cell cytoplasm) refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:t7kjbgqq+Vwy1Yu76EZZmPYhENg645098 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:803C722753C7CB3E|rigid:m48CD8Lb9Iljb0WpLtyKVj4J+wM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WMB5 uniprotkb:P11021 intact:EBI-6148584 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:ncap_measc(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:NP(gene name synonym)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:645098(measc)|taxid:645098("measles virus (strai") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155675|imex:IM-17331-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002021(Paramyxovirus nucleocapsid protein)|refseq:NP_056918.1|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0030430"(host cell cytoplasm) ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:t7kjbgqq+Vwy1Yu76EZZmPYhENg645098 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 intact-crc:803C722753C7CB3E|rigid:m48CD8Lb9Iljb0WpLtyKVj4J+wM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P24772 uniprotkb:Q02539 intact:EBI-4291651|uniprotkb:Q76ZK9 intact:EBI-932603|uniprotkb:Q3MJ34|ensembl:ENSP00000244573 psi-mi:b14_vaccw(display_long)|uniprotkb:B14R(orf name)|uniprotkb:VACWR196(locus name) psi-mi:h11_human(display_long)|uniprotkb:H1-1(gene name)|psi-mi:H1-1(display_short)|uniprotkb:H1F1(gene name synonym)|uniprotkb:HIST1H1A(gene name synonym)|uniprotkb:Histone H1a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155621|imex:IM-17331-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|refseq:YP_233078.1|interpro:IPR022819|interpro:IPR011212(Uncharacterised conserved protein UCP017324, VAC-B15)|rcsb pdb:2VVY|interpro:IPR043018 refseq:NP_005316.1|ensembl:ENSG00000124610(gene)|ensembl:ENST00000244573(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q02539|reactome:R-HSA-140342|reactome:R-HSA-2559584 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:DNsdHnOvi3bFP7ALXG9Wocbk3c010254 rogid:4u8P8jFM3onWx43+SxL320urjhk9606 intact-crc:845603737067E04E|rigid:Pe0LQwnlpEr3oWXzvb41uQrvY2U false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P24772 uniprotkb:O14920 intact:EBI-4291651|uniprotkb:Q76ZK9 intact:EBI-81266|uniprotkb:O75327|uniprotkb:B4E0U4|uniprotkb:B4DZ30|ensembl:ENSP00000430684 psi-mi:b14_vaccw(display_long)|uniprotkb:B14R(orf name)|uniprotkb:VACWR196(locus name) psi-mi:ikkb_human(display_long)|uniprotkb:IKBKB(gene name)|psi-mi:IKBKB(display_short)|uniprotkb:IKKB(gene name synonym)|uniprotkb:I-kappa-B kinase 2(gene name synonym)|uniprotkb:Nuclear factor NF-kappa-B inhibitor kinase beta(gene name synonym)|uniprotkb:Serine/threonine protein kinase IKBKB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155621|imex:IM-17331-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|refseq:YP_233078.1|interpro:IPR022819|interpro:IPR011212(Uncharacterised conserved protein UCP017324, VAC-B15)|rcsb pdb:2VVY|interpro:IPR043018 refseq:NP_001177649.1|refseq:NP_001547.1|interpro:IPR000626(Ubiquitin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR022007|interpro:IPR029071|interpro:IPR041185|go:"GO:1903347"(negative regulation of bicellular tight junction assembly)|go:"GO:1990459"(transferrin receptor binding)|mint:O14920|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:4E3C|rcsb pdb:4KIK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-209543|reactome:R-HSA-209560|ensembl:ENSG00000104365(gene)|ensembl:ENST00000520810(transcript)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002479"(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008384"(IkappaB kinase activity)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|reactome:R-HSA-445989|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|reactome:R-HSA-2871837|go:"GO:0019901"(protein kinase binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035509"(negative regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903140"(regulation of establishment of endothelial barrier)|refseq:NP_001229707.1|dip:DIP-27527N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:DNsdHnOvi3bFP7ALXG9Wocbk3c010254 rogid:Za/bWjmPFaKOGVvQ00rtBfikvhI9606 intact-crc:845603737067E04E|rigid:Pe0LQwnlpEr3oWXzvb41uQrvY2U false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P24772 uniprotkb:Q9BQE3 intact:EBI-4291651|uniprotkb:Q76ZK9 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:b14_vaccw(display_long)|uniprotkb:B14R(orf name)|uniprotkb:VACWR196(locus name) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155621|imex:IM-17331-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|refseq:YP_233078.1|interpro:IPR022819|interpro:IPR011212(Uncharacterised conserved protein UCP017324, VAC-B15)|rcsb pdb:2VVY|interpro:IPR043018 reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:DNsdHnOvi3bFP7ALXG9Wocbk3c010254 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:845603737067E04E|rigid:Pe0LQwnlpEr3oWXzvb41uQrvY2U false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P24772 uniprotkb:Q16543 intact:EBI-4291651|uniprotkb:Q76ZK9 intact:EBI-295634|uniprotkb:Q53YA2|ensembl:ENSP00000222005 psi-mi:b14_vaccw(display_long)|uniprotkb:B14R(orf name)|uniprotkb:VACWR196(locus name) psi-mi:cdc37_human(display_long)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:p50Cdc37(gene name synonym)|uniprotkb:CDC37A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155621|imex:IM-17331-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|refseq:YP_233078.1|interpro:IPR022819|interpro:IPR011212(Uncharacterised conserved protein UCP017324, VAC-B15)|rcsb pdb:2VVY|interpro:IPR043018 refseq:NP_008996.1|dip:DIP-27560N|ensembl:ENSG00000105401(gene)|ensembl:ENST00000222005(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006605"(protein targeting)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0101031"(chaperone complex)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|mint:Q16543|rcsb pdb:1US7|rcsb pdb:2K5B|rcsb pdb:2N5X|rcsb pdb:2NCA|rcsb pdb:2W0G|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5HPE|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-9013418|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:DNsdHnOvi3bFP7ALXG9Wocbk3c010254 rogid:iajhitd2iEmd17KfpU/nMaKc4049606 intact-crc:845603737067E04E|rigid:Pe0LQwnlpEr3oWXzvb41uQrvY2U false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P24772 uniprotkb:Q93008 intact:EBI-4291651|uniprotkb:Q76ZK9 intact:EBI-302524|intact:EBI-1058656|intact:EBI-28978998|ensembl:ENSP00000367558|uniprotkb:O75550|uniprotkb:Q8WWT3|uniprotkb:Q8WX12 psi-mi:b14_vaccw(display_long)|uniprotkb:B14R(orf name)|uniprotkb:VACWR196(locus name) psi-mi:usp9x_human(display_long)|uniprotkb:USP9X(gene name)|psi-mi:USP9X(display_short)|uniprotkb:DFFRX(gene name synonym)|uniprotkb:USP9(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease FAF-X(gene name synonym)|uniprotkb:Deubiquitinating enzyme FAF-X(gene name synonym)|uniprotkb:Fat facets protein-related, X-linked(gene name synonym)|uniprotkb:Ubiquitin-specific protease 9, X chromosome(gene name synonym)|uniprotkb:FAM(gene name synonym)|uniprotkb:Fat facets in mammals(gene name synonym)|uniprotkb:Ubiquitin thioesterase FAF-X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155621|imex:IM-17331-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|refseq:YP_233078.1|interpro:IPR022819|interpro:IPR011212(Uncharacterised conserved protein UCP017324, VAC-B15)|rcsb pdb:2VVY|interpro:IPR043018 ensembl:ENSG00000124486(gene)|ensembl:ENST00000378308(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007292"(female gamete generation)|go:"GO:0008104"(protein localization)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030426"(growth cone)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|reactome:R-HSA-2173795|reactome:R-HSA-5689880|reactome:R-HSA-8866652|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9033241|reactome:R-HSA-977225|go:"GO:0048675"(axon extension)|refseq:NP_001034679.2|refseq:NP_001034680.2|go:"GO:0050821"(protein stabilization)|go:"GO:0051301"(cell division)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0071947"(protein deubiquitination involved in ubiquitin-dependent protein catabolic process)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018200|interpro:IPR021905|interpro:IPR028889|interpro:IPR031226|interpro:IPR038765|mint:Q93008|rcsb pdb:5VBD|rcsb pdb:5WCH|ensembl:ENST00000324545|ensembl:ENSP00000316357|ensembl:ENSP00000367558|dip:DIP-27562N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:DNsdHnOvi3bFP7ALXG9Wocbk3c010254 rogid:f9AWz8rAV8rMTqcQ46VrYYLTHq89606 intact-crc:845603737067E04E|rigid:Pe0LQwnlpEr3oWXzvb41uQrvY2U false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P24772 uniprotkb:Q9Y6K9 intact:EBI-4291651|uniprotkb:Q76ZK9 intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662 psi-mi:b14_vaccw(display_long)|uniprotkb:B14R(orf name)|uniprotkb:VACWR196(locus name) psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155621|imex:IM-17331-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|refseq:YP_233078.1|interpro:IPR022819|interpro:IPR011212(Uncharacterised conserved protein UCP017324, VAC-B15)|rcsb pdb:2VVY|interpro:IPR043018 refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:DNsdHnOvi3bFP7ALXG9Wocbk3c010254 rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606 intact-crc:845603737067E04E|rigid:Pe0LQwnlpEr3oWXzvb41uQrvY2U false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P24772 uniprotkb:Q9P2P1 intact:EBI-4291651|uniprotkb:Q76ZK9 intact:EBI-954475|uniprotkb:Q86TR3|uniprotkb:Q9HAC4|uniprotkb:Q6P153|ensembl:ENSP00000371994 psi-mi:b14_vaccw(display_long)|uniprotkb:B14R(orf name)|uniprotkb:VACWR196(locus name) psi-mi:nynri_human(display_long)|uniprotkb:NYNRIN(gene name)|psi-mi:NYNRIN(display_short)|uniprotkb:CGIN1(gene name synonym)|uniprotkb:KIAA1305(gene name synonym)|uniprotkb:NYN domain and retroviral integrase catalytic domain-containing protein(gene name synonym)|uniprotkb:Protein cousin of GIN1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155621|imex:IM-17331-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|refseq:YP_233078.1|interpro:IPR022819|interpro:IPR011212(Uncharacterised conserved protein UCP017324, VAC-B15)|rcsb pdb:2VVY|interpro:IPR043018 ensembl:ENSG00000205978(gene)|ensembl:ENST00000382554(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0015074"(DNA integration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR001584(Integrase, catalytic core)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR021869|interpro:IPR036397|interpro:IPR041577|interpro:IPR041588|interpro:IPR043128|interpro:IPR043502|refseq:NP_079357.2|ensembl:ENSP00000371994 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:DNsdHnOvi3bFP7ALXG9Wocbk3c010254 rogid:gYRUd3QHFCJj80T+yxr+utG6KcQ9606 intact-crc:845603737067E04E|rigid:Pe0LQwnlpEr3oWXzvb41uQrvY2U false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P24772 uniprotkb:P54652 intact:EBI-4291651|uniprotkb:Q76ZK9 intact:EBI-356991|uniprotkb:Q15508|uniprotkb:Q53XM3|uniprotkb:Q9UE78|ensembl:ENSP00000247207|ensembl:ENSP00000378199 psi-mi:b14_vaccw(display_long)|uniprotkb:B14R(orf name)|uniprotkb:VACWR196(locus name) psi-mi:hsp72_human(display_long)|uniprotkb:HSPA2(gene name)|psi-mi:HSPA2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155621|imex:IM-17331-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|refseq:YP_233078.1|interpro:IPR022819|interpro:IPR011212(Uncharacterised conserved protein UCP017324, VAC-B15)|rcsb pdb:2VVY|interpro:IPR043018 refseq:NP_068814.2|ensembl:ENSG00000126803(gene)|ensembl:ENST00000247207(transcript)|ensembl:ENST00000394709(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0036128"(CatSper complex)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0048156"(tau protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051861"(glycolipid binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0072562"(blood microparticle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P54652|rcsb pdb:3I33|rcsb pdb:4FSV|rcsb pdb:5FPD|rcsb pdb:5FPE|rcsb pdb:5FPM|rcsb pdb:5FPN|reactome:R-HSA-1221632|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:DNsdHnOvi3bFP7ALXG9Wocbk3c010254 rogid:U+fdNfdxAWBQxDwSx0plk/iIBpM9606 intact-crc:845603737067E04E|rigid:Pe0LQwnlpEr3oWXzvb41uQrvY2U false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P24772 uniprotkb:Q9HCC0 intact:EBI-4291651|uniprotkb:Q76ZK9 intact:EBI-2211296|uniprotkb:A6NIY9|uniprotkb:Q96C27|uniprotkb:Q9Y4L7|ensembl:ENSP00000343657 psi-mi:b14_vaccw(display_long)|uniprotkb:B14R(orf name)|uniprotkb:VACWR196(locus name) psi-mi:mccb_human(display_long)|uniprotkb:MCCC2(gene name)|psi-mi:MCCC2(display_short)|uniprotkb:MCCB(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta"(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155621|imex:IM-17331-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|refseq:YP_233078.1|interpro:IPR022819|interpro:IPR011212(Uncharacterised conserved protein UCP017324, VAC-B15)|rcsb pdb:2VVY|interpro:IPR043018 refseq:NP_071415.1|refseq:XP_005248624.1|ensembl:ENSG00000131844(gene)|ensembl:ENST00000340941(transcript)|go:"GO:0002169"(3-methylcrotonyl-CoA carboxylase complex, mitochondrial)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR029045|interpro:IPR034733|mint:Q9HCC0|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70895 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:DNsdHnOvi3bFP7ALXG9Wocbk3c010254 rogid:5NkqDKqdX1wHsbqXW7v5+/Gld109606 intact-crc:845603737067E04E|rigid:Pe0LQwnlpEr3oWXzvb41uQrvY2U false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P24772 uniprotkb:P22492 intact:EBI-4291651|uniprotkb:Q76ZK9 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 psi-mi:b14_vaccw(display_long)|uniprotkb:B14R(orf name)|uniprotkb:VACWR196(locus name) psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155621|imex:IM-17331-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|refseq:YP_233078.1|interpro:IPR022819|interpro:IPR011212(Uncharacterised conserved protein UCP017324, VAC-B15)|rcsb pdb:2VVY|interpro:IPR043018 refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:DNsdHnOvi3bFP7ALXG9Wocbk3c010254 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 intact-crc:845603737067E04E|rigid:Pe0LQwnlpEr3oWXzvb41uQrvY2U false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P24772 uniprotkb:P08238 intact:EBI-4291651|uniprotkb:Q76ZK9 intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0 psi-mi:b14_vaccw(display_long)|uniprotkb:B14R(orf name)|uniprotkb:VACWR196(locus name) psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155621|imex:IM-17331-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|refseq:YP_233078.1|interpro:IPR022819|interpro:IPR011212(Uncharacterised conserved protein UCP017324, VAC-B15)|rcsb pdb:2VVY|interpro:IPR043018 ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:DNsdHnOvi3bFP7ALXG9Wocbk3c010254 rogid:wOsW7C10v2oMsM+REE38K6PAan09606 intact-crc:845603737067E04E|rigid:Pe0LQwnlpEr3oWXzvb41uQrvY2U false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P24772 uniprotkb:O15037 intact:EBI-4291651|uniprotkb:Q76ZK9 intact:EBI-6148525|uniprotkb:Q86TZ6|uniprotkb:Q8IUQ2|uniprotkb:Q96BA9|ensembl:ENSP00000251343|ensembl:ENSP00000450799|ensembl:ENSP00000451106 psi-mi:b14_vaccw(display_long)|uniprotkb:B14R(orf name)|uniprotkb:VACWR196(locus name) psi-mi:khnyn_human(display_long)|uniprotkb:KHNYN(gene name)|psi-mi:KHNYN(display_short)|uniprotkb:KH and NYN domain-containing protein(gene name synonym)|uniprotkb:KIAA0323(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155621|imex:IM-17331-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|refseq:YP_233078.1|interpro:IPR022819|interpro:IPR011212(Uncharacterised conserved protein UCP017324, VAC-B15)|rcsb pdb:2VVY|interpro:IPR043018 refseq:NP_056114.1|refseq:XP_005267531.1|refseq:NP_001277185.1|refseq:NP_001277186.1|ensembl:ENSG00000100441(gene)|ensembl:ENST00000251343(transcript)|ensembl:ENST00000553935(transcript)|ensembl:ENST00000556842(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR021869|interpro:IPR036612|mint:O15037|rcsb pdb:2N5M|rcsb pdb:2N7K - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:DNsdHnOvi3bFP7ALXG9Wocbk3c010254 rogid:vZgxwA7yR6mbBzxBvjkhMmhv5fY9606 intact-crc:845603737067E04E|rigid:Pe0LQwnlpEr3oWXzvb41uQrvY2U false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P24772 uniprotkb:P35268 intact:EBI-4291651|uniprotkb:Q76ZK9 intact:EBI-354533|intact:EBI-1055963|uniprotkb:Q6IBD1|uniprotkb:B2R495|ensembl:ENSP00000346088 psi-mi:b14_vaccw(display_long)|uniprotkb:B14R(orf name)|uniprotkb:VACWR196(locus name) psi-mi:rl22_human(display_long)|uniprotkb:RPL22(gene name)|psi-mi:RPL22(display_short)|uniprotkb:Heparin-binding protein HBp15(gene name synonym)|uniprotkb:Epstein-Barr virus small RNA-associated protein(gene name synonym)|uniprotkb:EBER-associated protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL22(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155621|imex:IM-17331-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|refseq:YP_233078.1|interpro:IPR022819|interpro:IPR011212(Uncharacterised conserved protein UCP017324, VAC-B15)|rcsb pdb:2VVY|interpro:IPR043018 refseq:NP_000974.1|ensembl:ENSG00000116251(gene)|ensembl:ENST00000234875(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008201"(heparin binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0045182"(translation regulator activity)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099577"(regulation of translation at presynapse, modulating synaptic transmission)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002671(Ribosomal protein L22e)|interpro:IPR038526|mint:P35268|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|reactome:R-HSA-72706|rcsb pdb:6Z6L|rcsb pdb:6Z6M|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:DNsdHnOvi3bFP7ALXG9Wocbk3c010254 rogid:0TVillnqDkHmdTwxIedAJCVAdzY9606 intact-crc:845603737067E04E|rigid:Pe0LQwnlpEr3oWXzvb41uQrvY2U false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P24772 uniprotkb:Q13085 intact:EBI-4291651|uniprotkb:Q76ZK9 intact:EBI-717681|intact:EBI-3962262|uniprotkb:B2ZZ90|uniprotkb:Q6KEV6|uniprotkb:Q6XDA8|uniprotkb:Q7Z2G8|uniprotkb:Q7Z561|uniprotkb:Q7Z563|uniprotkb:Q7Z564|uniprotkb:Q86WB2|uniprotkb:Q86WB3|uniprotkb:B2RP68|ensembl:ENSP00000478547|ensembl:ENSP00000483674 psi-mi:b14_vaccw(display_long)|uniprotkb:B14R(orf name)|uniprotkb:VACWR196(locus name) psi-mi:acaca_human(display_long)|uniprotkb:ACACA(gene name)|psi-mi:ACACA(display_short)|uniprotkb:ACAC(gene name synonym)|uniprotkb:ACC1(gene name synonym)|uniprotkb:ACCA(gene name synonym)|uniprotkb:Acetyl-Coenzyme A carboxylase alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155621|imex:IM-17331-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|refseq:YP_233078.1|interpro:IPR022819|interpro:IPR011212(Uncharacterised conserved protein UCP017324, VAC-B15)|rcsb pdb:2VVY|interpro:IPR043018 refseq:NP_942131.1|refseq:NP_942133.1|refseq:NP_942134.1|refseq:NP_942135.1|refseq:NP_942136.1|refseq:XP_016880044.1|refseq:XP_011523005.1|ensembl:ENSG00000275176(gene)|ensembl:ENSG00000278540(gene)|ensembl:ENST00000613687(transcript)|ensembl:ENST00000614428(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003989"(acetyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019538"(protein metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:2001295"(malonyl-CoA biosynthetic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013537(Acetyl-CoA carboxylase, central region)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR029045|interpro:IPR034733|mint:Q13085|rcsb pdb:2YL2|rcsb pdb:3COJ|rcsb pdb:4ASI|rcsb pdb:6G2D|rcsb pdb:6G2H|rcsb pdb:6G2I|reactome:R-HSA-163765|reactome:R-HSA-196780|reactome:R-HSA-200425|reactome:R-HSA-2426168|reactome:R-HSA-3371599|reactome:R-HSA-75105|dip:DIP-36122N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:DNsdHnOvi3bFP7ALXG9Wocbk3c010254 rogid:P9d0QlkoP1zrBdF1WOrK68ueGng9606 intact-crc:845603737067E04E|rigid:Pe0LQwnlpEr3oWXzvb41uQrvY2U false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P24772 uniprotkb:O15111 intact:EBI-4291651|uniprotkb:Q76ZK9 intact:EBI-81249|uniprotkb:O14666|uniprotkb:Q13132|uniprotkb:Q5W0I4|uniprotkb:Q92467|ensembl:ENSP00000359424|intact:EBI-28970970 psi-mi:b14_vaccw(display_long)|uniprotkb:B14R(orf name)|uniprotkb:VACWR196(locus name) psi-mi:ikka_human(display_long)|uniprotkb:CHUK(gene name)|psi-mi:CHUK(display_short)|uniprotkb:IKKA(gene name synonym)|uniprotkb:TCF16(gene name synonym)|uniprotkb:I-kappa-B kinase 1(gene name synonym)|uniprotkb:Conserved helix-loop-helix ubiquitous kinase(gene name synonym)|uniprotkb:Nuclear factor NF-kappa-B inhibitor kinase alpha(gene name synonym)|uniprotkb:Transcription factor 16(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155621|imex:IM-17331-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|refseq:YP_233078.1|interpro:IPR022819|interpro:IPR011212(Uncharacterised conserved protein UCP017324, VAC-B15)|rcsb pdb:2VVY|interpro:IPR043018 refseq:NP_001269.3|ensembl:ENSP00000359424|ensembl:ENSG00000213341(gene)|ensembl:ENST00000370397(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008384"(IkappaB kinase activity)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0061847"(response to cholecystokinin)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0010034"(response to acetate)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022007|interpro:IPR041185|mint:O15111|rcsb pdb:3BRT|rcsb pdb:5EBZ|rcsb pdb:5TQW|rcsb pdb:5TQX|rcsb pdb:5TQY|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-198323|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5674400|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|dip:DIP-27526N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:DNsdHnOvi3bFP7ALXG9Wocbk3c010254 rogid:FVB/gXjSBTB9hdq9pycQogxesms9606 intact-crc:845603737067E04E|rigid:Pe0LQwnlpEr3oWXzvb41uQrvY2U false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P24772 uniprotkb:Q71U36 intact:EBI-4291651|uniprotkb:Q76ZK9 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:b14_vaccw(display_long)|uniprotkb:B14R(orf name)|uniprotkb:VACWR196(locus name) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155621|imex:IM-17331-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|refseq:YP_233078.1|interpro:IPR022819|interpro:IPR011212(Uncharacterised conserved protein UCP017324, VAC-B15)|rcsb pdb:2VVY|interpro:IPR043018 refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:DNsdHnOvi3bFP7ALXG9Wocbk3c010254 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 intact-crc:845603737067E04E|rigid:Pe0LQwnlpEr3oWXzvb41uQrvY2U false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:Q13330 intact:EBI-6148716 intact:EBI-714236|uniprotkb:Q8NFI8|uniprotkb:Q96GI8|uniprotkb:A5PLK4|intact:EBI-28976623|ensembl:ENSP00000333633|uniprotkb:Q86SW2 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:mta1_human(display_long)|uniprotkb:MTA1(gene name)|psi-mi:MTA1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) refseq:NP_001190187.1|refseq:NP_004680.2|ensembl:ENSP00000333633|ensembl:ENST00000405646|ensembl:ENSP00000384180|ensembl:ENST00000438610|ensembl:ENSP00000393438|ensembl:ENSG00000182979(gene)|ensembl:ENST00000331320(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|reactome:R-HSA-427389|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|reactome:R-HSA-3232118|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR035170|interpro:IPR040138|mint:Q13330|rcsb pdb:4BKX|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:5FXY|rcsb pdb:5ICN|rcsb pdb:6G16|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AO8|go:"GO:0045475"(locomotor rhythm)|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-3214815|dip:DIP-41751N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:nDDSb5B6YCbq5/6qvgtnUWtP23M9606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:Q9BQE3 intact:EBI-6148716 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:Q5VTE0 intact:EBI-6148716 intact:EBI-877809 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:ef1a3_human(display_long)|uniprotkb:EEF1A1P5(gene name)|psi-mi:EEF1A1P5(display_short)|uniprotkb:Eukaryotic elongation factor 1 A-like 3(gene name synonym)|uniprotkb:EEF1AL3(gene name synonym)|uniprotkb:Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR031157|reactome:R-HSA-156842|interpro:IPR027417 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:3t6tj3i+3CKTC1NsrHyBkeoRK789606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:P68104 intact:EBI-6148716 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:Q9UPU5 intact:EBI-6148716 intact:EBI-1642365|uniprotkb:Q6ZSY2|uniprotkb:Q8N2Y4|uniprotkb:Q9NXD1|ensembl:ENSP00000294383 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:ubp24_human(display_long)|uniprotkb:USP24(gene name)|psi-mi:USP24(display_short)|uniprotkb:KIAA1057(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 24(gene name synonym)|uniprotkb:Deubiquitinating enzyme 24(gene name synonym)|uniprotkb:Ubiquitin thioesterase 24(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000162402(gene)|ensembl:ENST00000294383(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018200|interpro:IPR021905|interpro:IPR028889|refseq:NP_056121.2|interpro:IPR029071|interpro:IPR033382|mint:Q9UPU5|reactome:R-HSA-5689880|interpro:IPR038765 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:JJq+mHZKczkuP54nocU+Y9HXaQ49606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:O60341 intact:EBI-6148716 intact:EBI-710124|uniprotkb:Q5TH94|uniprotkb:Q5TH95|uniprotkb:Q86VT7|uniprotkb:Q8IXK4|uniprotkb:Q8NDP6|uniprotkb:Q8TAZ3|uniprotkb:Q96AW4|ensembl:ENSP00000349049|uniprotkb:A8MWP9 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:kdm1a_human(display_long)|uniprotkb:Flavin-containing amine oxidase domain-containing protein 2(gene name synonym)|uniprotkb:BRAF35-HDAC complex protein BHC110(gene name synonym)|uniprotkb:KDM1A(gene name)|psi-mi:KDM1A(display_short)|uniprotkb:KIAA0601(gene name synonym)|uniprotkb:LSD1(gene name synonym)|uniprotkb:AOF2(gene name synonym)|uniprotkb:KDM1(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) go:"GO:0021987"(cerebral cortex development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032451"(demethylase activity)|refseq:NP_001009999.1|refseq:NP_055828.2|ensembl:ENSG00000004487(gene)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|ensembl:ENST00000356634(transcript)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-34641N|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0033184"(positive regulation of histone ubiquitination)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042551"(neuron maturation)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043426"(MRF binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046098"(guanine metabolic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0060992"(response to fungicide)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1903827"|go:"GO:1990391"(DNA repair complex)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR002937(Amine oxidase)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017366(Histone lysine-specific demethylase)|interpro:IPR036188|interpro:IPR036388|mint:O60341|rcsb pdb:2COM|rcsb pdb:2DW4|rcsb pdb:2EJR|rcsb pdb:2H94|rcsb pdb:2HKO|rcsb pdb:2IW5|rcsb pdb:2L3D|rcsb pdb:2UXN|rcsb pdb:2UXX|rcsb pdb:2V1D|rcsb pdb:2X0L|rcsb pdb:2XAF|rcsb pdb:2XAG|rcsb pdb:2XAH|rcsb pdb:2XAJ|rcsb pdb:2XAQ|rcsb pdb:2XAS|rcsb pdb:2Y48|rcsb pdb:2Z3Y|rcsb pdb:2Z5U|rcsb pdb:3ABT|rcsb pdb:3ABU|rcsb pdb:3ZMS|rcsb pdb:3ZMT|rcsb pdb:3ZMU|rcsb pdb:3ZMV|rcsb pdb:3ZMZ|rcsb pdb:3ZN0|rcsb pdb:3ZN1|rcsb pdb:4BAY|rcsb pdb:4CZZ|rcsb pdb:4KUM|rcsb pdb:4UV8|rcsb pdb:4UV9|rcsb pdb:4UVA|rcsb pdb:4UVB|rcsb pdb:4UVC|rcsb pdb:4UXN|rcsb pdb:4XBF|rcsb pdb:5AFW|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5IT3|rcsb pdb:5L3B|rcsb pdb:5L3C|rcsb pdb:5L3D|rcsb pdb:5L3E|rcsb pdb:5L3F|rcsb pdb:5L3G|rcsb pdb:5LBQ|rcsb pdb:5LGN|rcsb pdb:5LGT|rcsb pdb:5LGU|rcsb pdb:5LHG|rcsb pdb:5LHH|rcsb pdb:5LHI|rcsb pdb:5X60|rcsb pdb:5YJB|rcsb pdb:6E1F|rcsb pdb:6K3E|rcsb pdb:6KGK|rcsb pdb:6KGL|rcsb pdb:6KGM|rcsb pdb:6KGN|rcsb pdb:6KGO|rcsb pdb:6KGP|rcsb pdb:6KGQ|rcsb pdb:6KGR|rcsb pdb:6NQM|rcsb pdb:6NQU|rcsb pdb:6NR5|rcsb pdb:6S35|rcsb pdb:6TE1|rcsb pdb:6VYP|rcsb pdb:6W4K|rcsb pdb:6WC6|rcsb pdb:7CDC|rcsb pdb:7CDD|rcsb pdb:7CDE|rcsb pdb:7CDF|rcsb pdb:7CDG|rcsb pdb:7E0G|rcsb pdb:7JJL|rcsb pdb:7JJM|rcsb pdb:7JK7|reactome:R-HSA-3214815|reactome:R-HSA-3214842|reactome:R-HSA-5625886|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9679191|reactome:R-HSA-983231 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:rS9F23Rg1Ha6XOQSisWQfhKVFfs9606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:Q92598 intact:EBI-6148716 intact:EBI-356829|uniprotkb:O95739|uniprotkb:Q5TBM6|uniprotkb:Q5TBM8|uniprotkb:Q9UPC4|uniprotkb:Q5TBM7|intact:EBI-2859494|uniprotkb:B4DYH1|ensembl:ENSP00000318687 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:hs105_human(display_long)|uniprotkb:HSPH1(gene name)|psi-mi:HSPH1(display_short)|uniprotkb:HSP105(gene name synonym)|uniprotkb:HSP110(gene name synonym)|uniprotkb:KIAA0201(gene name synonym)|uniprotkb:Heat shock 110 kDa protein(gene name synonym)|uniprotkb:Antigen NY-CO-25(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) refseq:NP_001273432.1|refseq:NP_001273433.1|refseq:NP_001273434.1|refseq:NP_006635.2|ensembl:ENSG00000120694(gene)|ensembl:ENST00000320027(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051135"(positive regulation of NK T cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042053|interpro:IPR043129|mint:Q92598|rcsb pdb:6GFA|reactome:R-HSA-3000484|reactome:R-HSA-3371453 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:FSdvp2KDHLmNpceRJ9HLY5IBfQA9606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:P07900 intact:EBI-6148716 intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|ensembl:ENSP00000216281|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) go:"GO:0009409"(response to cold)|go:"GO:0016020"(membrane)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|ensembl:ENST00000216281(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000080824(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043335"(protein unfolding)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1UY8|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2BYH|rcsb pdb:2VCJ|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3B24|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5LO1|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6CYH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7LSZ|rcsb pdb:7LT0|reactome:R-HSA-1227986|reactome:R-HSA-1236382|rcsb pdb:6TN4|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9665233|reactome:R-HSA-9664565|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3K99|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:3T0H|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:4YKZ|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|refseq:NP_001017963.2|refseq:NP_005339.3|dip:DIP-27595N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:Q16576 intact:EBI-6148716 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:P34932 intact:EBI-6148716 intact:EBI-356933|uniprotkb:O95756|uniprotkb:Q2TAL4|uniprotkb:Q9BUK9|ensembl:ENSP00000302961 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:hsp74_human(display_long)|uniprotkb:HSPA4(gene name)|psi-mi:HSPA4(display_short)|uniprotkb:APG2(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-2(gene name synonym)|uniprotkb:HSP70RY(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) refseq:NP_002145.3|dip:DIP-460N|ensembl:ENSG00000170606(gene)|ensembl:ENST00000304858(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042052|interpro:IPR043129|mint:P34932|reactome:R-HSA-3371453 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:4OkTlG9p3IQQBYloiuHS8+t13TM9606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:P49411 intact:EBI-6148716 intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:P11021 intact:EBI-6148716 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:P55795 intact:EBI-6148716 intact:EBI-352823|ensembl:ENSP00000361927|uniprotkb:Q9HHA7|uniprotkb:A1L400 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:hnrh2_human(display_long)|uniprotkb:HNRNPH2(gene name)|psi-mi:HNRNPH2(display_short)|uniprotkb:FTP3(gene name synonym)|uniprotkb:HNRPH2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein H'(gene name synonym)|uniprotkb:FTP-3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000126945(gene)|ensembl:ENST00000316594(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P55795|rcsb pdb:1WEZ|rcsb pdb:1WG5|rcsb pdb:6DG1|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001027565.1|refseq:NP_062543.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:811j5syFsbk/QSaZv/ag9QsFUEQ9606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:P56545 intact:EBI-6148716 intact:EBI-741533|uniprotkb:O43449|uniprotkb:Q5SQP7|uniprotkb:Q69YI3|uniprotkb:Q86SV0|uniprotkb:Q9H2T8|uniprotkb:A8K2X5|ensembl:ENSP00000338615|ensembl:ENSP00000410474|ensembl:ENSP00000434630|ensembl:ENSP00000436285|uniprotkb:D3DRF5|uniprotkb:Q8IY44|intact:EBI-11742664 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:ctbp2_human(display_long)|uniprotkb:CTBP2(gene name)|psi-mi:CTBP2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) refseq:NP_001077383.1|refseq:NP_001320.1|refseq:NP_073713.2|refseq:NP_001307943.1|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:P56545|rcsb pdb:2OME|rcsb pdb:4LCJ|rcsb pdb:6WKW|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-9662360|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|ensembl:ENSG00000175029(gene)|ensembl:ENST00000337195(transcript)|ensembl:ENST00000411419(transcript)|ensembl:ENST00000494626(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|ensembl:ENST00000531469(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|refseq:XP_011537653.1|refseq:XP_011537655.1|refseq:XP_011537656.1|refseq:XP_011537657.1|refseq:NP_001307941.1|refseq:NP_001307942.1|refseq:XP_005269618.1|refseq:XP_005269621.1|refseq:XP_005269624.1|refseq:XP_005269625.1|refseq:XP_005269626.1|refseq:XP_005269628.1|refseq:XP_005269629.1|refseq:NP_001277143.1|refseq:NP_001277144.1|refseq:XP_006717705.1|refseq:XP_016871245.1|refseq:XP_016871246.1|dip:DIP-42104N|refseq:XP_011537651.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:6sKiqjMRW/ViEvTbQJoaUjgvZtc9606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:O14654 intact:EBI-6148716 intact:EBI-356594|ensembl:ENSP00000505547 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:Q13547 intact:EBI-6148716 intact:EBI-301834|uniprotkb:Q92534|ensembl:ENSP00000362649 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:hdac1_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:RPD3L1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000116478(gene)|ensembl:ENST00000373548(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043044"|go:"GO:0019213"(deacetylase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q13547|rcsb pdb:1TYI|rcsb pdb:4BKX|rcsb pdb:5ICN|rcsb pdb:6Z2J|rcsb pdb:6Z2K|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-193670|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-3769402|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-4641265|reactome:R-HSA-6804758|reactome:R-HSA-69205|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9022538|reactome:R-HSA-9022692|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9615017|reactome:R-HSA-9679191|reactome:R-HSA-983231|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:NP_004955.2|dip:DIP-24184N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:O95816 intact:EBI-6148716 intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:P49368 intact:EBI-6148716 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:P31943 intact:EBI-6148716 intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168|ensembl:ENSP00000377082|ensembl:ENSP00000397797|ensembl:ENSP00000492076|ensembl:ENSP00000495786 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) refseq:NP_005511.1|refseq:NP_001244222.1|ensembl:ENSG00000169045(gene)|ensembl:ENSG00000284254(gene)|ensembl:ENST00000356731(transcript)|ensembl:ENST00000393432(transcript)|ensembl:ENST00000442819(transcript)|ensembl:ENST00000638505(transcript)|ensembl:ENST00000643310(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:Q05639 intact:EBI-6148716 intact:EBI-354943|ensembl:ENSP00000217182|uniprotkb:P54266|uniprotkb:Q0VGC7|uniprotkb:B5BUF3|uniprotkb:E1P5J1 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:ef1a2_human(display_long)|uniprotkb:EEF1A2(gene name)|psi-mi:EEF1A2(display_short)|uniprotkb:EEF1AL(gene name synonym)|uniprotkb:STN(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-2(gene name synonym)|uniprotkb:Statin-S1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000101210(gene)|ensembl:ENST00000217182(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0090218"(positive regulation of lipid kinase activity)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:Q05639|rcsb pdb:3C5J|reactome:R-HSA-156842|refseq:NP_001949.1|dip:DIP-40060N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:vFXfcSRokxKo5RW0tRE1qEK0NKw9606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:Q71U36 intact:EBI-6148716 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:P07437 intact:EBI-6148716 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:Q92769 intact:EBI-6148716 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:Q09028 intact:EBI-6148716 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:Q92618 intact:EBI-6148716 intact:EBI-2799490|intact:EBI-28975450|ensembl:ENSP00000394757 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:zn516_human(display_long)|uniprotkb:KIAA0222(gene name synonym)|uniprotkb:ZNF516(gene name)|psi-mi:ZNF516(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) ensembl:ENSP00000394757|refseq:XP_011524571.1|refseq:XP_011524572.1|refseq:XP_011524573.1|refseq:XP_011524574.1|refseq:XP_011524575.1|refseq:XP_011524576.1|refseq:XP_011524577.1|refseq:NP_055458.1|ensembl:ENSG00000101493(gene)|ensembl:ENST00000443185(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009409"(response to cold)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q92618|refseq:XP_016881586.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:L9yQp1u4G/AN1L79Bg8odnkiPi89606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:Q13363 intact:EBI-6148716 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:O94776 intact:EBI-6148716 intact:EBI-1783035|uniprotkb:Q68DB1|uniprotkb:Q9UQB5|ensembl:ENSP00000278823 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:mta2_human(display_long)|uniprotkb:MTA2(gene name)|psi-mi:MTA2(display_short)|uniprotkb:MTA1L1(gene name synonym)|uniprotkb:PID(gene name synonym)|uniprotkb:Metastasis-associated 1-like 1(gene name synonym)|uniprotkb:p53 target protein in deacetylase complex(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) refseq:NP_004730.2|refseq:NP_001317221.1|dip:DIP-46519N|ensembl:ENSG00000149480(gene)|ensembl:ENST00000278823(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006306"(DNA methylation)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016020"(membrane)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR035170|interpro:IPR037964|interpro:IPR040138|interpro:IPR043151|mint:O94776|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:D4wOsdMJYhY/ltvcnnuMHqNrFkc9606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:P52597 intact:EBI-6148716 intact:EBI-352986|ensembl:ENSP00000338477|ensembl:ENSP00000349573|ensembl:ENSP00000400433|ensembl:ENSP00000438061|ensembl:ENSP00000507787|ensembl:ENSP00000348345|uniprotkb:Q5T0N2|uniprotkb:Q96AU2|uniprotkb:B3KM84 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:hnrpf_human(display_long)|uniprotkb:HNRNPF(gene name)|psi-mi:HNRNPF(display_short)|uniprotkb:HNRPF(gene name synonym)|uniprotkb:Nucleolin-like protein mcs94-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P52597|rcsb pdb:2HGL|rcsb pdb:2HGM|rcsb pdb:2HGN|rcsb pdb:2KFY|rcsb pdb:2KG0|rcsb pdb:2KG1|rcsb pdb:3TFY|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensembl:ENSG00000169813(gene)|ensembl:ENST00000337970(transcript)|ensembl:ENST00000356053(transcript)|ensembl:ENST00000357065(transcript)|ensembl:ENST00000443950(transcript)|ensembl:ENST00000544000(transcript)|ensembl:ENST00000682386(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001091674.1|refseq:NP_001091675.1|refseq:NP_001091676.1|refseq:NP_001091677.1|refseq:NP_001091678.1|refseq:NP_004957.1|dip:DIP-33145N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:pblzpldZOa5vlZ+zGQY9qyWCxaw9606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1C4 uniprotkb:P68371 intact:EBI-6148716 intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289 psi-mi:ltp_muhvk(display_long)|uniprotkb:M48(gene name)|psi-mi:M48(display_short) psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155797|imex:IM-17331-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR034702|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR038765|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus) refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:LPTx4T0YcrCS8/sy1M0+LU82lyI69156 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606 intact-crc:EBCE6BCCF39AC9C2|rigid:CikSB8FSapEbKjJmEHgUBmM7eKs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P11207 uniprotkb:Q13619 intact:EBI-6148694 intact:EBI-456106|uniprotkb:O75834|uniprotkb:Q589T6|uniprotkb:Q5TC62|uniprotkb:Q6UP08|uniprotkb:Q9UP17|uniprotkb:A2A2W2|ensembl:ENSP00000364589 psi-mi:v_piv5(display_long)|uniprotkb:P/V(gene name)|psi-mi:P/V(display_short) psi-mi:cul4a_human(display_long)|uniprotkb:CUL4A(gene name)|psi-mi:CUL4A(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11208(sv5)|taxid:11208("Simian virus 5 (strain W3)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155782|imex:IM-17331-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P11207|dip:DIP-48759N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR024279|interpro:IPR025909|rcsb pdb:2HYE|rcsb pdb:2K48|rcsb pdb:4I1S|rcsb pdb:2B5L refseq:NP_001008895.1|refseq:NP_003580.1|refseq:NP_001265442.1|refseq:XP_011535825.1|dip:DIP-31610N|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13619|rcsb pdb:2HYE|rcsb pdb:4A0K|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|ensembl:ENSG00000139842(gene)|ensembl:ENST00000375440(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:cmlnevM0HJgKJibzPH+KhOrSiKc11208 rogid:xYRRxjpO/9qqeXtq9dfACAdqyM89606 intact-crc:7ED7617939EDEE7F|rigid:PlLy0RfWnDj77A2jP/CNqga/I6E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P11207 uniprotkb:Q9BW61 intact:EBI-6148694 intact:EBI-2510241|ensembl:ENSP00000352928|ensembl:ENSP00000472171|ensembl:ENSP00000473086 psi-mi:v_piv5(display_long)|uniprotkb:P/V(gene name)|psi-mi:P/V(display_short) psi-mi:dda1_human(display_long)|uniprotkb:DDA1(gene name)|psi-mi:DDA1(display_short)|uniprotkb:C19orf58(gene name synonym)|uniprotkb:PCIA1(gene name synonym)|uniprotkb:Placenta cross-immune reaction antigen 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11208(sv5)|taxid:11208("Simian virus 5 (strain W3)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155782|imex:IM-17331-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P11207|dip:DIP-48759N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR024279|interpro:IPR025909|rcsb pdb:2HYE|rcsb pdb:2K48|rcsb pdb:4I1S|rcsb pdb:2B5L ensembl:ENSG00000130311(gene)|ensembl:ENST00000359866(transcript)|ensembl:ENST00000593466(transcript)|ensembl:ENST00000596582(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR018276|interpro:IPR033575|mint:Q9BW61|rcsb pdb:6DSZ|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6SJ7|rcsb pdb:6UD7|rcsb pdb:6UE5|reactome:R-HSA-8951664|refseq:NP_076955.1|dip:DIP-53527N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:cmlnevM0HJgKJibzPH+KhOrSiKc11208 rogid:yD3tRVKVhirdHUj58DCTphW7ZYs9606 intact-crc:7ED7617939EDEE7F|rigid:PlLy0RfWnDj77A2jP/CNqga/I6E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P11207 uniprotkb:Q16531 intact:EBI-6148694 intact:EBI-350322|uniprotkb:A6NG77|uniprotkb:O15176|uniprotkb:Q13289|ensembl:ENSP00000301764|ensembl:ENSP00000506223|ensembl:ENSP00000506685|uniprotkb:Q58F96|uniprotkb:B2R648|uniprotkb:B4DG00 psi-mi:v_piv5(display_long)|uniprotkb:P/V(gene name)|psi-mi:P/V(display_short) psi-mi:ddb1_human(display_long)|uniprotkb:DDB1(gene name)|psi-mi:DDB1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym)|uniprotkb:DNA damage-binding protein a(gene name synonym)|uniprotkb:UV-damaged DNA-binding protein 1(gene name synonym)|uniprotkb:Xeroderma pigmentosum group E-complementing protein(gene name synonym)|uniprotkb:XPE-binding factor(gene name synonym)|uniprotkb:HBV X-associated protein 1(gene name synonym)|uniprotkb:XAP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11208(sv5)|taxid:11208("Simian virus 5 (strain W3)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155782|imex:IM-17331-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P11207|dip:DIP-48759N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR024279|interpro:IPR025909|rcsb pdb:2HYE|rcsb pdb:2K48|rcsb pdb:4I1S|rcsb pdb:2B5L refseq:NP_001914.3|rcsb pdb:3I89|rcsb pdb:3I8C|rcsb pdb:3I8E|rcsb pdb:4A08|rcsb pdb:4A09|rcsb pdb:4A0A|rcsb pdb:4A0B|rcsb pdb:4A0K|rcsb pdb:4A0L|rcsb pdb:4A11|rcsb pdb:4CI1|rcsb pdb:4CI2|rcsb pdb:4CI3|rcsb pdb:4E54|rcsb pdb:4E5Z|rcsb pdb:4TZ4|rcsb pdb:5FQD|rcsb pdb:5HXB|rcsb pdb:5JK7|rcsb pdb:5V3O|rcsb pdb:6BN7|ensembl:ENSG00000167986(gene)|ensembl:ENST00000301764(transcript)|ensembl:ENST00000680367(transcript)|ensembl:ENST00000681803(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BOY|rcsb pdb:6DSZ|rcsb pdb:6FCV|rcsb pdb:6H0F|rcsb pdb:6H0G|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6SJ7|rcsb pdb:6TD3|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:6UML|rcsb pdb:6XK9|rcsb pdb:7LPS|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|interpro:IPR036322|mint:Q16531|rcsb pdb:2B5L|rcsb pdb:2B5M|rcsb pdb:2B5N|rcsb pdb:2HYE|rcsb pdb:3E0C|rcsb pdb:3EI1|rcsb pdb:3EI2|rcsb pdb:3EI3|rcsb pdb:3EI4|rcsb pdb:3I7H|rcsb pdb:3I7K|rcsb pdb:3I7L|rcsb pdb:3I7N|rcsb pdb:3I7O|rcsb pdb:3I7P|dip:DIP-430N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:cmlnevM0HJgKJibzPH+KhOrSiKc11208 rogid:qgMjZqvlsbGIGn2qM/pnLTtGyGM9606 intact-crc:7ED7617939EDEE7F|rigid:PlLy0RfWnDj77A2jP/CNqga/I6E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q02539 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-932603|uniprotkb:Q3MJ34|ensembl:ENSP00000244573 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h11_human(display_long)|uniprotkb:H1-1(gene name)|psi-mi:H1-1(display_short)|uniprotkb:H1F1(gene name synonym)|uniprotkb:HIST1H1A(gene name synonym)|uniprotkb:Histone H1a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155720|imex:IM-17331-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_005316.1|ensembl:ENSG00000124610(gene)|ensembl:ENST00000244573(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q02539|reactome:R-HSA-140342|reactome:R-HSA-2559584 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:4u8P8jFM3onWx43+SxL320urjhk9606 intact-crc:E4EDF7AEA2E0DB39 false tandem tag:?-?|mutation:38-38,106-106,184-184,103-103 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P31943 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168|ensembl:ENSP00000377082|ensembl:ENSP00000397797|ensembl:ENSP00000492076|ensembl:ENSP00000495786 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155720|imex:IM-17331-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_005511.1|refseq:NP_001244222.1|ensembl:ENSG00000169045(gene)|ensembl:ENSG00000284254(gene)|ensembl:ENST00000356731(transcript)|ensembl:ENST00000393432(transcript)|ensembl:ENST00000442819(transcript)|ensembl:ENST00000638505(transcript)|ensembl:ENST00000643310(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606 intact-crc:E4EDF7AEA2E0DB39 false tandem tag:?-?|mutation:38-38,106-106,184-184,103-103 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q08211 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352022|intact:EBI-1058470|uniprotkb:Q5VY62|uniprotkb:Q6PD69|uniprotkb:Q99556|uniprotkb:B2RNV4|uniprotkb:Q05CI5|uniprotkb:Q12803|uniprotkb:Q32Q22|ensembl:ENSP00000356520 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:dhx9_human(display_long)|uniprotkb:DHX9(gene name)|psi-mi:DHX9(display_short)|uniprotkb:DDX9(gene name synonym)|uniprotkb:NDH2(gene name synonym)|uniprotkb:DExH-box helicase 9(gene name synonym)|uniprotkb:RNA helicase A(gene name synonym)|uniprotkb:LKP(gene name synonym)|uniprotkb:Nuclear DNA helicase II(gene name synonym)|uniprotkb:DEAH box protein 9(gene name synonym)|uniprotkb:Leukophysin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155720|imex:IM-17331-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001348.2|dip:DIP-31504N|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033679"(3'-5' DNA/RNA helicase activity)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045142"(triplex DNA binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0097165"(nuclear stress granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1905172"(RISC complex binding)|go:"GO:1905538"(polysome binding)|go:"GO:1905698"(positive regulation of polysome binding)|go:"GO:1990518"(single-stranded 3'-5' DNA helicase activity)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000765"(regulation of cytoplasmic translation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR044445|interpro:IPR044446|interpro:IPR044447|mint:Q08211|rcsb pdb:3LLM|rcsb pdb:3VYX|rcsb pdb:3VYY|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-72163|go:"GO:1904973"(positive regulation of viral translation)|ensembl:ENSG00000135829(gene)|ensembl:ENST00000367549(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006260"(DNA replication)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0016604"(nuclear body) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:b0VP2Frtvwa9WbYVMwB6TbV2uGU9606 intact-crc:E4EDF7AEA2E0DB39 false tandem tag:?-?|mutation:38-38,106-106,184-184,103-103 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 intact:EBI-6147672 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 - psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:p0c7m2_human(display_short)|psi-mi:EBI-6147672(display_long) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155720|imex:IM-17331-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 uniprotkb:P0C7M2(uniprot-removed-ac) - - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 - intact-crc:E4EDF7AEA2E0DB39 false tandem tag:?-?|mutation:38-38,106-106,184-184,103-103 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q92804 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-2255091|uniprotkb:B2R837|uniprotkb:Q92751|intact:EBI-3867593|uniprotkb:Q86X94|ensembl:ENSP00000474096|ensembl:ENSP00000480040 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rbp56_human(display_long)|uniprotkb:TAF15(gene name)|psi-mi:TAF15(display_short)|uniprotkb:RBP56(gene name synonym)|uniprotkb:TAF2N(gene name synonym)|uniprotkb:RNA-binding protein 56(gene name synonym)|uniprotkb:68 kDa TATA-binding protein-associated factor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155720|imex:IM-17331-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_003478.1|refseq:NP_631961.1|dip:DIP-52760N|ensembl:ENSG00000270647(gene)|ensembl:ENSG00000276833(gene)|ensembl:ENST00000605844(transcript)|ensembl:ENST00000617382(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048255"(mRNA stabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034870|interpro:IPR034875|interpro:IPR035979|interpro:IPR036443|mint:Q92804|rcsb pdb:2MMY|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:9+wyDu+1dvocxFI4GKvLqkvChDc9606 intact-crc:E4EDF7AEA2E0DB39 false tandem tag:?-?|mutation:38-38,106-106,184-184,103-103 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:O14654 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-356594|ensembl:ENSP00000505547 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155720|imex:IM-17331-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606 intact-crc:E4EDF7AEA2E0DB39 false tandem tag:?-?|mutation:38-38,106-106,184-184,103-103 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P68371 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155720|imex:IM-17331-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606 intact-crc:E4EDF7AEA2E0DB39 false tandem tag:?-?|mutation:38-38,106-106,184-184,103-103 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q99729 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155720|imex:IM-17331-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 intact-crc:E4EDF7AEA2E0DB39 false tandem tag:?-?|mutation:38-38,106-106,184-184,103-103 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P27986 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-79464|intact:EBI-28974553|ensembl:ENSP00000428056|ensembl:ENSP00000429277|uniprotkb:Q15747|uniprotkb:Q4VBZ7|uniprotkb:Q53EM6|uniprotkb:Q8IXA2|uniprotkb:Q8N1C5|uniprotkb:D3DWA0|uniprotkb:B3KT19|uniprotkb:E7EX19 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:p85a_human(display_long)|uniprotkb:PIK3R1(gene name)|psi-mi:PIK3R1(display_short)|uniprotkb:GRB1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155720|imex:IM-17331-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001229395.1|refseq:NP_852556.2|refseq:NP_852664.1|refseq:NP_852665.1|ensembl:ENSG00000145675(gene)|ensembl:ENST00000521381(transcript)|ensembl:ENST00000521657(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|ensembl:ENST00000320694|ensembl:ENSP00000323512|ensembl:ENST00000336483|ensembl:ENSP00000338554|ensembl:ENSP00000428056|ensembl:ENSP00000429277|ensembl:ENST00000523872|ensembl:ENSP00000430098|rcsb pdb:5SXA|rcsb pdb:5SXB|rcsb pdb:5SXC|rcsb pdb:5SXD|rcsb pdb:5SXE|rcsb pdb:5SXF|rcsb pdb:5SXI|rcsb pdb:5SXJ|rcsb pdb:5SXK|rcsb pdb:5UBT|rcsb pdb:5UK8|rcsb pdb:5UKJ|rcsb pdb:5SX9|rcsb pdb:5UL1|rcsb pdb:5VLR|rcsb pdb:5XGH|rcsb pdb:5XGI|rcsb pdb:5XGJ|rcsb pdb:6NCT|rcsb pdb:6PYR|rcsb pdb:6PYU|reactome:R-HSA-1660499|rcsb pdb:7CIO|rcsb pdb:7LM2|reactome:R-HSA-180292|reactome:R-HSA-109704|reactome:R-HSA-1839117|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1236382|reactome:R-HSA-186763|reactome:R-HSA-1963642|reactome:R-HSA-1250342|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-198203|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-1433557|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-430116|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654689|reactome:R-HSA-5654695|reactome:R-HSA-5654710|reactome:R-HSA-5654720|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9603381|reactome:R-HSA-9607240|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-983695|reactome:R-HSA-5655253|reactome:R-HSA-5655302|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-6811558|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-5655291|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9027276|reactome:R-HSA-9028335|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0043559"(insulin binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1990578"(perinuclear endoplasmic reticulum membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035591|interpro:IPR036028|interpro:IPR036860|interpro:IPR044124|mint:P27986|rcsb pdb:1A0N|rcsb pdb:1AZG|rcsb pdb:1H9O|rcsb pdb:1PBW|rcsb pdb:1PHT|rcsb pdb:1PIC|rcsb pdb:1PKS|rcsb pdb:1PKT|rcsb pdb:2IUG|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|rcsb pdb:2IUH|rcsb pdb:2IUI|rcsb pdb:2RD0|rcsb pdb:3HHM|rcsb pdb:3HIZ|rcsb pdb:3I5R|rcsb pdb:3I5S|rcsb pdb:4A55|rcsb pdb:4JPS|rcsb pdb:4L1B|rcsb pdb:4L23|rcsb pdb:4L2Y|rcsb pdb:4OVU|rcsb pdb:4OVV|rcsb pdb:4WAF|rcsb pdb:4YKN|rcsb pdb:4ZOP|rcsb pdb:5AUL|rcsb pdb:5FI4|rcsb pdb:5GJI|rcsb pdb:5ITD|rcsb pdb:5M6U|rcsb pdb:5SW8|rcsb pdb:5SWG|rcsb pdb:5SWO|rcsb pdb:2V1Y|rcsb pdb:5SWP|rcsb pdb:5SWR|rcsb pdb:5SWT|rcsb pdb:5SX8|refseq:XP_016865074.1|refseq:XP_005248599.1|dip:DIP-119N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:pANLtVCSWVr64OXaS6bCjGBwfig9606 intact-crc:E4EDF7AEA2E0DB39 false tandem tag:?-?|mutation:38-38,106-106,184-184,103-103 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P31942 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-711437|uniprotkb:Q9NPI4|uniprotkb:Q9UFU4|uniprotkb:Q9Y4J5|uniprotkb:Q9BSX1|uniprotkb:Q9NP53|uniprotkb:Q9NP96|uniprotkb:Q9NPA7|ensembl:ENSP00000265866|uniprotkb:A8K682|uniprotkb:B3KRE1 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrh3_human(display_long)|uniprotkb:HNRNPH3(gene name)|psi-mi:HNRNPH3(display_short)|uniprotkb:HNRPH3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein 2H9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155720|imex:IM-17331-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000096746(gene)|ensembl:ENST00000265866(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034969|interpro:IPR034970|interpro:IPR035979|mint:P31942|refseq:NP_036339.1|refseq:NP_067676.2|refseq:NP_001309363.1|refseq:NP_001309365.1|refseq:NP_001309366.1|refseq:NP_001309367.1|refseq:NP_001309368.1|refseq:NP_001309369.1|refseq:NP_001309370.1|refseq:NP_001309374.1|refseq:NP_001309375.1|refseq:NP_001309376.1|refseq:NP_001309377.1|refseq:NP_001309378.1|refseq:XP_016871657.1|refseq:XP_016871658.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:iJGBIhPXnQIIFQmgxWB1WjwVXSY9606 intact-crc:E4EDF7AEA2E0DB39 false tandem tag:?-?|mutation:38-38,106-106,184-184,103-103 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P35637 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-400434|uniprotkb:Q9H4A8|ensembl:ENSP00000254108 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:fus_human(display_long)|uniprotkb:FUS(gene name)|psi-mi:FUS(display_short)|uniprotkb:TLS(gene name synonym)|uniprotkb:Oncogene FUS(gene name synonym)|uniprotkb:Oncogene TLS(gene name synonym)|uniprotkb:Translocated in liposarcoma protein(gene name synonym)|uniprotkb:POMp75(gene name synonym)|uniprotkb:75 kDa DNA-pairing protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155720|imex:IM-17331-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001164105.1|refseq:NP_004951.1|ensembl:ENSG00000089280(gene)|ensembl:ENST00000254108(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008380"(RNA splicing)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044327"(dendritic spine head)|go:"GO:0046872"(metal ion binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034459|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:P35637|rcsb pdb:2LA6|rcsb pdb:2LCW|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:5W3N|rcsb pdb:5XRR|rcsb pdb:5XSG|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:6BWZ|rcsb pdb:6BXV|rcsb pdb:6BZP|rcsb pdb:6G99|rcsb pdb:6GBM|rcsb pdb:6KJ1|rcsb pdb:6KJ2|rcsb pdb:6KJ3|rcsb pdb:6KJ4|rcsb pdb:6SNJ|rcsb pdb:6XFM|rcsb pdb:7CYL|reactome:R-HSA-72163|dip:DIP-29857N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:HUP4fGXQyJnm5CFTuwjTpiucZOc9606 intact-crc:E4EDF7AEA2E0DB39 false tandem tag:?-?|mutation:38-38,106-106,184-184,103-103 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P09651 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352662|uniprotkb:Q3MIB7|uniprotkb:Q6PJZ7|ensembl:ENSP00000341826|ensembl:ENSP00000503610|uniprotkb:A8K4Z8|intact:EBI-2556572 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:roa1_human(display_long)|uniprotkb:HNRNPA1(gene name)|psi-mi:HNRNPA1(display_short)|uniprotkb:HNRPA1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:Single-strand RNA-binding protein(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155720|imex:IM-17331-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_002127.1|refseq:NP_112420.1|ensembl:ENSG00000135486(gene)|ensembl:ENST00000340913(transcript)|ensembl:ENST00000677210(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|rcsb pdb:2LYV|rcsb pdb:2UP1|rcsb pdb:4YOE|rcsb pdb:5MPG|rcsb pdb:5MPL|rcsb pdb:5ZGD|rcsb pdb:5ZGL|rcsb pdb:6BXX|rcsb pdb:6DCL|rcsb pdb:6J60|rcsb pdb:7BX7|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035198"(miRNA binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051170"(import into nucleus)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR034845|interpro:IPR035979|mint:P09651|rcsb pdb:1HA1|rcsb pdb:1L3K|rcsb pdb:1PGZ|rcsb pdb:1PO6|rcsb pdb:1U1K|rcsb pdb:1U1L|rcsb pdb:1U1M|rcsb pdb:1U1N|rcsb pdb:1U1O|rcsb pdb:1U1P|rcsb pdb:1U1Q|rcsb pdb:1U1R|rcsb pdb:1UP1|rcsb pdb:2H4M|refseq:XP_005268883.1|dip:DIP-29338N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:ECXjsLRVtNc/aOw90tEFxowHc6c9606 intact-crc:E4EDF7AEA2E0DB39 false tandem tag:?-?|mutation:38-38,106-106,184-184,103-103 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P42336 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-2116585|uniprotkb:Q14CW1|uniprotkb:Q99762|ensembl:ENSP00000263967 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pk3ca_human(display_long)|uniprotkb:Phosphoinositide-3-kinase catalytic alpha polypeptide(gene name synonym)|uniprotkb:Serine/threonine protein kinase PIK3CA(gene name synonym)|uniprotkb:PIK3CA(gene name)|psi-mi:PIK3CA(display_short)|uniprotkb:Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha(gene name synonym)|uniprotkb:Phosphoinositide 3-kinase alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155720|imex:IM-17331-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:XP_011511196.1|refseq:XP_006713721.1|refseq:NP_006209.2|dip:DIP-42728N|ensembl:ENSG00000121879(gene)|ensembl:ENST00000263967(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001944"(vasculature development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0005944"(phosphatidylinositol 3-kinase complex, class IB)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006909"(phagocytosis)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030168"(platelet activation)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035004"(phosphatidylinositol 3-kinase activity)|go:"GO:0035005"(1-phosphatidylinositol-4-phosphate 3-kinase activity)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0038028"(insulin receptor signaling pathway via phosphatidylinositol 3-kinase)|go:"GO:0038084"(vascular endothelial growth factor signaling pathway)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0043276"(anoikis)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044029"(hypomethylation of CpG island)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046934"(phosphatidylinositol-4,5-bisphosphate 3-kinase activity)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110053"(regulation of actin filament organization)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR000341(Phosphoinositide 3-kinase, ras-binding)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR003113(Phosphatidylinositol 3-kinase, p85-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR029071|interpro:IPR035892|interpro:IPR036940|interpro:IPR037704|interpro:IPR042236|mint:P42336|rcsb pdb:2ENQ|rcsb pdb:2RD0|rcsb pdb:3HHM|rcsb pdb:3HIZ|rcsb pdb:3ZIM|rcsb pdb:4JPS|rcsb pdb:4L1B|rcsb pdb:4L23|rcsb pdb:4L2Y|rcsb pdb:4OVU|rcsb pdb:4OVV|rcsb pdb:4TUU|rcsb pdb:4TV3|rcsb pdb:4WAF|rcsb pdb:4YKN|rcsb pdb:4ZOP|rcsb pdb:5DXT|rcsb pdb:5FI4|rcsb pdb:5ITD|rcsb pdb:5SW8|rcsb pdb:5SWG|rcsb pdb:5SWO|rcsb pdb:5SWP|rcsb pdb:5SWR|rcsb pdb:5SWT|rcsb pdb:5SX8|rcsb pdb:5SX9|rcsb pdb:5SXA|rcsb pdb:5SXB|rcsb pdb:5SXC|rcsb pdb:5SXD|rcsb pdb:5SXE|rcsb pdb:5SXF|rcsb pdb:5SXI|rcsb pdb:5SXJ|rcsb pdb:5SXK|rcsb pdb:5UBR|rcsb pdb:5UK8|rcsb pdb:5UKJ|rcsb pdb:5UL1|rcsb pdb:5XGH|rcsb pdb:5XGI|rcsb pdb:5XGJ|rcsb pdb:6GVF|rcsb pdb:6GVG|rcsb pdb:6GVH|rcsb pdb:6GVI|rcsb pdb:6NCT|rcsb pdb:6OAC|rcsb pdb:6PYS|rcsb pdb:6VO7|rcsb pdb:7JIU|rcsb pdb:7K6M|rcsb pdb:7K6N|rcsb pdb:7K6O|rcsb pdb:7K71|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1236382|reactome:R-HSA-1250342|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-180292|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-1963642|reactome:R-HSA-198203|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654689|reactome:R-HSA-5654695|reactome:R-HSA-5654710|reactome:R-HSA-5654720|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-9009391|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9027276|reactome:R-HSA-9028335|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9603381|reactome:R-HSA-9607240|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|rcsb pdb:5DXH|reactome:R-HSA-9703465|reactome:R-HSA-9703648 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:YIZWt9VfCmyBCWYkqAEaMAEsl3w9606 intact-crc:E4EDF7AEA2E0DB39 false tandem tag:?-?|mutation:38-38,106-106,184-184,103-103 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:O00459 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-346930|uniprotkb:Q5EAT5|uniprotkb:Q9UPH9|intact:EBI-28974273|ensembl:ENSP00000222254 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:p85b_human(display_long)|uniprotkb:PIK3R2(gene name)|psi-mi:PIK3R2(display_short)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155720|imex:IM-17331-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSP00000222254|refseq:NP_005018.1|dip:DIP-31811N|ensembl:ENSG00000105647(gene)|ensembl:ENST00000222254(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|rcsb pdb:6OX7|rcsb pdb:6U28|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-186763|reactome:R-HSA-198203|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|mint:O00459|rcsb pdb:2KT1|rcsb pdb:2XS6|rcsb pdb:3MTT|rcsb pdb:3O5Z|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-210993|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9013409 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:Ij0WS0eKPwShgFWQc7OEss7AcAU9606 intact-crc:E4EDF7AEA2E0DB39 false tandem tag:?-?|mutation:38-38,106-106,184-184,103-103 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P22626 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155720|imex:IM-17331-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606 intact-crc:E4EDF7AEA2E0DB39 false tandem tag:?-?|mutation:38-38,106-106,184-184,103-103 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P62269 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352451|ensembl:ENSP00000211372|ensembl:ENSP00000393241|ensembl:ENSP00000403175|ensembl:ENSP00000412583|ensembl:ENSP00000416110|uniprotkb:P25232|uniprotkb:Q6IPF8|uniprotkb:Q5SUJ3 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs18_human(display_long)|uniprotkb:RPS18(gene name)|psi-mi:RPS18(display_short)|uniprotkb:D6S218E(gene name synonym)|uniprotkb:Ke-3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS13(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155720|imex:IM-17331-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_072045.1|ensembl:ENSG00000096150(gene)|ensembl:ENSG00000223367(gene)|ensembl:ENSG00000226225(gene)|ensembl:ENSG00000231500(gene)|ensembl:ENSG00000235650(gene)|ensembl:ENST00000211372(transcript)|ensembl:ENST00000434122(transcript)|ensembl:ENST00000439602(transcript)|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENST00000454021(transcript)|ensembl:ENST00000457341(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001892(Ribosomal protein S13)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR018269|interpro:IPR027437|mint:P62269|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|dip:DIP-32892N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:yOHgKM/BuvgGdqp1OEVPeuiABg89606 intact-crc:E4EDF7AEA2E0DB39 false tandem tag:?-?|mutation:38-38,106-106,184-184,103-103 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q32P51 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-2556580|uniprotkb:Q5TBS2|ensembl:ENSP00000350090 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ra1l2_human(display_long)|uniprotkb:HNRNPA1L(gene name synonym)|uniprotkb:HNRNPA1L2(gene name)|psi-mi:HNRNPA1L2(display_short)|uniprotkb:hnRNP core protein A1-like 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155720|imex:IM-17331-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001011724.1|refseq:NP_001011725.1|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0051028"(mRNA transport)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR035979|mint:Q32P51|go:"GO:0005681"(spliceosomal complex)|ensembl:ENSG00000139675(gene)|ensembl:ENST00000357495(transcript)|go:"GO:0003723"(RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:Xx00SLimJrf+0e9CrvzUV9PJPcI9606 intact-crc:E4EDF7AEA2E0DB39 false tandem tag:?-?|mutation:38-38,106-106,184-184,103-103 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P22492 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155720|imex:IM-17331-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 intact-crc:E4EDF7AEA2E0DB39 false tandem tag:?-?|mutation:38-38,106-106,184-184,103-103 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q84940 uniprotkb:Q7L7L0 intact:EBI-6148816|uniprotkb:Q85037 intact:EBI-5325551|ensembl:ENSP00000355656|ensembl:ENSP00000493926|uniprotkb:B2R4S4 psi-mi:nsp1_rotp5(display_long)|uniprotkb:NCVP2(gene name synonym)|uniprotkb:Non-structural RNA-binding protein 53(gene name synonym) psi-mi:h2a3_human(display_long)|uniprotkb:H2AW(gene name)|psi-mi:H2AW(display_short)|uniprotkb:HIST3H2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10915(rotp5)|taxid:10915("Rotavirus A (strain Pig/United States/OSU/1977 G5-P9[7]-I5-R1-C1-M1-A1-N1-T1-E1-H1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155890|imex:IM-17331-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002148(Non-structural RNA-binding protein 53, rotavirus)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0044163"(host cytoskeleton)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000181218(gene)|ensembl:ENSG00000284841(gene)|ensembl:ENST00000366695(transcript)|refseq:NP_254280.1|ensembl:ENST00000645741(transcript)|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-5689603|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q7L7L0|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000786"(nucleosome)|dip:DIP-48936N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OysqOFnFAKSWxRtIAcBkE5mUOnw10915 rogid:t0RdR1SmUtmwRjtCS3uTyLGqSUI9606 intact-crc:341F49EB89C237BE|rigid:AvlhLqDhf+qNNGerq11PxOVoIsE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q84940 uniprotkb:Q15370 intact:EBI-6148816|uniprotkb:Q85037 intact:EBI-301238|ensembl:ENSP00000386652|uniprotkb:B7WPD3 psi-mi:nsp1_rotp5(display_long)|uniprotkb:NCVP2(gene name synonym)|uniprotkb:Non-structural RNA-binding protein 53(gene name synonym) psi-mi:elob_human(display_long)|uniprotkb:ELOB(gene name)|psi-mi:ELOB(display_short)|uniprotkb:Elongin 18 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit B(gene name synonym)|uniprotkb:SIII p18(gene name synonym)|uniprotkb:TCEB2(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10915(rotp5)|taxid:10915("Rotavirus A (strain Pig/United States/OSU/1977 G5-P9[7]-I5-R1-C1-M1-A1-N1-T1-E1-H1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155890|imex:IM-17331-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002148(Non-structural RNA-binding protein 53, rotavirus)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0044163"(host cytoskeleton)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000103363(gene)|ensembl:ENST00000409906(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039049|mint:Q15370|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2JZ3|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:4WQO|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:6SIS|refseq:NP_009039.1|refseq:NP_996896.1|dip:DIP-29570N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OysqOFnFAKSWxRtIAcBkE5mUOnw10915 rogid:apX4QFpDC4Dz3MAs7tQ8+XFHx6I9606 intact-crc:341F49EB89C237BE|rigid:AvlhLqDhf+qNNGerq11PxOVoIsE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q84940 uniprotkb:Q16777 intact:EBI-6148816|uniprotkb:Q85037 intact:EBI-5325566|ensembl:ENSP00000332194|uniprotkb:Q6DRA7|uniprotkb:Q8IUE5 psi-mi:nsp1_rotp5(display_long)|uniprotkb:NCVP2(gene name synonym)|uniprotkb:Non-structural RNA-binding protein 53(gene name synonym) psi-mi:h2a2c_human(display_long)|uniprotkb:H2AC20(gene name)|psi-mi:H2AC20(display_short)|uniprotkb:H2A-clustered histone 20(gene name synonym)|uniprotkb:H2AFQ(gene name synonym)|uniprotkb:HIST2H2AC(gene name synonym)|uniprotkb:Histone H2A-GL101(gene name synonym)|uniprotkb:Histone H2A/q(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10915(rotp5)|taxid:10915("Rotavirus A (strain Pig/United States/OSU/1977 G5-P9[7]-I5-R1-C1-M1-A1-N1-T1-E1-H1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155890|imex:IM-17331-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002148(Non-structural RNA-binding protein 53, rotavirus)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0044163"(host cytoskeleton)|go:"GO:0046872"(metal ion binding) reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-5689603|ensembl:ENSG00000184260(gene)|ensembl:ENST00000331380(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q16777|rcsb pdb:6Y5E|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|refseq:NP_003508.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OysqOFnFAKSWxRtIAcBkE5mUOnw10915 rogid:Wejrpp9wK3GvA4ahJDVyEH+cwlQ9606 intact-crc:341F49EB89C237BE|rigid:AvlhLqDhf+qNNGerq11PxOVoIsE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q84940 uniprotkb:P62861 intact:EBI-6148816|uniprotkb:Q85037 intact:EBI-358093|uniprotkb:Q05472|uniprotkb:Q95261|uniprotkb:Q9H5V4|ensembl:ENSP00000431822|ensembl:ENSP00000434440|ensembl:ENSP00000435370 psi-mi:nsp1_rotp5(display_long)|uniprotkb:NCVP2(gene name synonym)|uniprotkb:Non-structural RNA-binding protein 53(gene name synonym) psi-mi:rs30_human(display_long)|uniprotkb:FAU(gene name)|psi-mi:FAU(display_short)|uniprotkb:Small ribosomal subunit protein eS30(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10915(rotp5)|taxid:10915("Rotavirus A (strain Pig/United States/OSU/1977 G5-P9[7]-I5-R1-C1-M1-A1-N1-T1-E1-H1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155890|imex:IM-17331-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002148(Non-structural RNA-binding protein 53, rotavirus)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0044163"(host cytoskeleton)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000149806(gene)|ensembl:ENST00000527548(transcript)|ensembl:ENST00000529639(transcript)|ensembl:ENST00000531743(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR006846(Ribosomal protein S30)|mint:P62861|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OysqOFnFAKSWxRtIAcBkE5mUOnw10915 rogid:mfW+tko85h9ZOK7wNXUsYiYY3Hc9606 intact-crc:341F49EB89C237BE|rigid:AvlhLqDhf+qNNGerq11PxOVoIsE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q84940 uniprotkb:Q6FI13 intact:EBI-6148816|uniprotkb:Q85037 intact:EBI-353620|uniprotkb:P20670|uniprotkb:B2R5F0|ensembl:ENSP00000358155|ensembl:ENSP00000475814 psi-mi:nsp1_rotp5(display_long)|uniprotkb:NCVP2(gene name synonym)|uniprotkb:Non-structural RNA-binding protein 53(gene name synonym) psi-mi:h2a2a_human(display_long)|uniprotkb:H2AC18(gene name)|psi-mi:H2AC18(display_short)|uniprotkb:H2AC19(gene name)|psi-mi:H2AC19(display_short)|uniprotkb:H2A-clustered histone 18(gene name synonym)|uniprotkb:H2A-clustered histone 19(gene name synonym)|uniprotkb:H2AFO(gene name synonym)|uniprotkb:HIST2H2AA(gene name synonym)|uniprotkb:HIST2H2AA3(gene name synonym)|uniprotkb:HIST2H2AA4(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/o(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10915(rotp5)|taxid:10915("Rotavirus A (strain Pig/United States/OSU/1977 G5-P9[7]-I5-R1-C1-M1-A1-N1-T1-E1-H1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155890|imex:IM-17331-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002148(Non-structural RNA-binding protein 53, rotavirus)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0044163"(host cytoskeleton)|go:"GO:0046872"(metal ion binding) refseq:NP_001035807.1|refseq:NP_003507.1|ensembl:ENSG00000203812(gene)|ensembl:ENSG00000272196(gene)|ensembl:ENST00000369159(transcript)|ensembl:ENST00000607355(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6Y5D|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|dip:DIP-33167N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OysqOFnFAKSWxRtIAcBkE5mUOnw10915 rogid:PMuIm2XMN5q4wk+wYJ94mmnCe4w9606 intact-crc:341F49EB89C237BE|rigid:AvlhLqDhf+qNNGerq11PxOVoIsE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q84940 uniprotkb:Q13618 intact:EBI-6148816|uniprotkb:Q85037 intact:EBI-456129|uniprotkb:O75415|uniprotkb:Q569L3|uniprotkb:Q9UBI8|uniprotkb:B8ZZC3|uniprotkb:Q9UET7|uniprotkb:A8K536|ensembl:ENSP00000264414 psi-mi:nsp1_rotp5(display_long)|uniprotkb:NCVP2(gene name synonym)|uniprotkb:Non-structural RNA-binding protein 53(gene name synonym) psi-mi:cul3_human(display_long)|uniprotkb:CUL3(gene name)|psi-mi:CUL3(display_short)|uniprotkb:KIAA0617(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10915(rotp5)|taxid:10915("Rotavirus A (strain Pig/United States/OSU/1977 G5-P9[7]-I5-R1-C1-M1-A1-N1-T1-E1-H1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155890|imex:IM-17331-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002148(Non-structural RNA-binding protein 53, rotavirus)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0044163"(host cytoskeleton)|go:"GO:0046872"(metal ion binding) refseq:NP_003581.1|refseq:NP_001244126.1|refseq:NP_001244127.1|dip:DIP-31611N|ensembl:ENSG00000036257(gene)|ensembl:ENST00000264414(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000922"(spindle pole)|go:"GO:0001831"(trophectodermal cellular morphogenesis)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005827"(polar microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017145"(stem cell division)|go:"GO:0030030"(cell projection organization)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031208"(POZ domain binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044346"(fibroblast apoptotic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071630"(nuclear protein quality control by the ubiquitin-proteasome system)|go:"GO:0072576"(liver morphogenesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1901992"(positive regulation of mitotic cell cycle phase transition)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13618|rcsb pdb:2MYL|rcsb pdb:2MYM|rcsb pdb:4AP2|rcsb pdb:4APF|rcsb pdb:4EOZ|rcsb pdb:4HXI|rcsb pdb:5NLB|rcsb pdb:6I2M|reactome:R-HSA-4641258|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-8932339|reactome:R-HSA-8951664|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9706019|reactome:R-HSA-983168 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OysqOFnFAKSWxRtIAcBkE5mUOnw10915 rogid:xI/8pHB9nckOW629STOqKba4KzQ9606 intact-crc:341F49EB89C237BE|rigid:AvlhLqDhf+qNNGerq11PxOVoIsE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q84940 uniprotkb:Q93077 intact:EBI-6148816|uniprotkb:Q85037 intact:EBI-725259|uniprotkb:O00775|uniprotkb:O00776|uniprotkb:O00777|uniprotkb:O00778|uniprotkb:Q540R1|uniprotkb:B2R4F7|ensembl:ENSP00000321389|ensembl:ENSP00000367022|ensembl:ENSP00000473534 psi-mi:nsp1_rotp5(display_long)|uniprotkb:NCVP2(gene name synonym)|uniprotkb:Non-structural RNA-binding protein 53(gene name synonym) psi-mi:h2a1c_human(display_long)|uniprotkb:H2AC6(gene name)|psi-mi:H2AC6(display_short)|uniprotkb:H2A-clustered histone 6(gene name synonym)|uniprotkb:H2AFL(gene name synonym)|uniprotkb:HIST1H2AC(gene name synonym)|uniprotkb:Histone H2A/l(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10915(rotp5)|taxid:10915("Rotavirus A (strain Pig/United States/OSU/1977 G5-P9[7]-I5-R1-C1-M1-A1-N1-T1-E1-H1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155890|imex:IM-17331-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002148(Non-structural RNA-binding protein 53, rotavirus)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0044163"(host cytoskeleton)|go:"GO:0046872"(metal ion binding) refseq:NP_003503.1|ensembl:ENSG00000180573(gene)|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENST00000314088(transcript)|ensembl:ENST00000377791(transcript)|ensembl:ENST00000602637(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|rcsb pdb:6C0W|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:7A08|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|interpro:IPR032458 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OysqOFnFAKSWxRtIAcBkE5mUOnw10915 rogid:m00IdooZksbNGKHSsaVvGFVpcko9606 intact-crc:341F49EB89C237BE|rigid:AvlhLqDhf+qNNGerq11PxOVoIsE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q84940 uniprotkb:P54652 intact:EBI-6148816|uniprotkb:Q85037 intact:EBI-356991|uniprotkb:Q15508|uniprotkb:Q53XM3|uniprotkb:Q9UE78|ensembl:ENSP00000247207|ensembl:ENSP00000378199 psi-mi:nsp1_rotp5(display_long)|uniprotkb:NCVP2(gene name synonym)|uniprotkb:Non-structural RNA-binding protein 53(gene name synonym) psi-mi:hsp72_human(display_long)|uniprotkb:HSPA2(gene name)|psi-mi:HSPA2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10915(rotp5)|taxid:10915("Rotavirus A (strain Pig/United States/OSU/1977 G5-P9[7]-I5-R1-C1-M1-A1-N1-T1-E1-H1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155890|imex:IM-17331-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002148(Non-structural RNA-binding protein 53, rotavirus)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0044163"(host cytoskeleton)|go:"GO:0046872"(metal ion binding) refseq:NP_068814.2|ensembl:ENSG00000126803(gene)|ensembl:ENST00000247207(transcript)|ensembl:ENST00000394709(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0036128"(CatSper complex)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0048156"(tau protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051861"(glycolipid binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0072562"(blood microparticle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P54652|rcsb pdb:3I33|rcsb pdb:4FSV|rcsb pdb:5FPD|rcsb pdb:5FPE|rcsb pdb:5FPM|rcsb pdb:5FPN|reactome:R-HSA-1221632|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OysqOFnFAKSWxRtIAcBkE5mUOnw10915 rogid:U+fdNfdxAWBQxDwSx0plk/iIBpM9606 intact-crc:341F49EB89C237BE|rigid:AvlhLqDhf+qNNGerq11PxOVoIsE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q84940 uniprotkb:P34931 intact:EBI-6148816|uniprotkb:Q85037 intact:EBI-354912|uniprotkb:O75634|uniprotkb:Q2HXR3|uniprotkb:Q8NE72|uniprotkb:A6NNB0|uniprotkb:Q96QC9|uniprotkb:Q9UQM1|uniprotkb:B0UXW8|ensembl:ENSP00000364805|ensembl:ENSP00000372881|ensembl:ENSP00000396486|ensembl:ENSP00000408347 psi-mi:nsp1_rotp5(display_long)|uniprotkb:NCVP2(gene name synonym)|uniprotkb:Non-structural RNA-binding protein 53(gene name synonym) psi-mi:hs71l_human(display_long)|uniprotkb:HSPA1L(gene name)|psi-mi:HSPA1L(display_short)|uniprotkb:Heat shock 70 kDa protein 1-Hom(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10915(rotp5)|taxid:10915("Rotavirus A (strain Pig/United States/OSU/1977 G5-P9[7]-I5-R1-C1-M1-A1-N1-T1-E1-H1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155890|imex:IM-17331-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002148(Non-structural RNA-binding protein 53, rotavirus)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0044163"(host cytoskeleton)|go:"GO:0046872"(metal ion binding) refseq:NP_005518.3|ensembl:ENSG00000204390(gene)|ensembl:ENSG00000206383(gene)|ensembl:ENSG00000234258(gene)|ensembl:ENSG00000236251(gene)|ensembl:ENST00000375654(transcript)|ensembl:ENST00000383390(transcript)|ensembl:ENST00000417601(transcript)|ensembl:ENST00000456772(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0072562"(blood microparticle)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P34931|rcsb pdb:3GDQ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OysqOFnFAKSWxRtIAcBkE5mUOnw10915 rogid:KS02DcMpD2sxSF36hUjKiSdYi4c9606 intact-crc:341F49EB89C237BE|rigid:AvlhLqDhf+qNNGerq11PxOVoIsE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q84940 uniprotkb:P62805 intact:EBI-6148816|uniprotkb:Q85037 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:nsp1_rotp5(display_long)|uniprotkb:NCVP2(gene name synonym)|uniprotkb:Non-structural RNA-binding protein 53(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10915(rotp5)|taxid:10915("Rotavirus A (strain Pig/United States/OSU/1977 G5-P9[7]-I5-R1-C1-M1-A1-N1-T1-E1-H1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155890|imex:IM-17331-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002148(Non-structural RNA-binding protein 53, rotavirus)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0044163"(host cytoskeleton)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OysqOFnFAKSWxRtIAcBkE5mUOnw10915 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:341F49EB89C237BE|rigid:AvlhLqDhf+qNNGerq11PxOVoIsE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q84940 uniprotkb:P17066 intact:EBI-6148816|uniprotkb:Q85037 intact:EBI-355106|uniprotkb:Q8IYK7|uniprotkb:Q9BT95|uniprotkb:Q1HBA8|ensembl:ENSP00000310219 psi-mi:nsp1_rotp5(display_long)|uniprotkb:NCVP2(gene name synonym)|uniprotkb:Non-structural RNA-binding protein 53(gene name synonym) psi-mi:hsp76_human(display_long)|uniprotkb:HSPA6(gene name)|psi-mi:HSPA6(display_short)|uniprotkb:HSP70B'(gene name synonym)|uniprotkb:Heat shock 70 kDa protein B'(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10915(rotp5)|taxid:10915("Rotavirus A (strain Pig/United States/OSU/1977 G5-P9[7]-I5-R1-C1-M1-A1-N1-T1-E1-H1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155890|imex:IM-17331-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002148(Non-structural RNA-binding protein 53, rotavirus)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0044163"(host cytoskeleton)|go:"GO:0046872"(metal ion binding) refseq:NP_002146.2|ensembl:ENSG00000173110(gene)|ensembl:ENST00000309758(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P17066|rcsb pdb:3FE1|reactome:R-HSA-3371453|reactome:R-HSA-6798695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OysqOFnFAKSWxRtIAcBkE5mUOnw10915 rogid:AcNwJ2S/RD3n/8iRNy5ioetVZ+U9606 intact-crc:341F49EB89C237BE|rigid:AvlhLqDhf+qNNGerq11PxOVoIsE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q84940 uniprotkb:Q99878 intact:EBI-6148816|uniprotkb:Q85037 intact:EBI-6147676|uniprotkb:Q5JXQ5|uniprotkb:A2RUU6|ensembl:ENSP00000328484 psi-mi:nsp1_rotp5(display_long)|uniprotkb:NCVP2(gene name synonym)|uniprotkb:Non-structural RNA-binding protein 53(gene name synonym) psi-mi:h2a1j_human(display_long)|uniprotkb:H2AC14(gene name)|psi-mi:H2AC14(display_short)|uniprotkb:H2AFE(gene name synonym)|uniprotkb:HIST1H2AJ(gene name synonym)|uniprotkb:Histone H2A/e(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10915(rotp5)|taxid:10915("Rotavirus A (strain Pig/United States/OSU/1977 G5-P9[7]-I5-R1-C1-M1-A1-N1-T1-E1-H1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155890|imex:IM-17331-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002148(Non-structural RNA-binding protein 53, rotavirus)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0044163"(host cytoskeleton)|go:"GO:0046872"(metal ion binding) refseq:NP_066544.1|ensembl:ENSG00000276368(gene)|ensembl:ENST00000333151(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OysqOFnFAKSWxRtIAcBkE5mUOnw10915 rogid:tS29VG3PpglHaYbu0w5z7pGvYyI9606 intact-crc:341F49EB89C237BE|rigid:AvlhLqDhf+qNNGerq11PxOVoIsE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q84940 uniprotkb:Q96KK5 intact:EBI-6148816|uniprotkb:Q85037 intact:EBI-6147668|ensembl:ENSP00000366679 psi-mi:nsp1_rotp5(display_long)|uniprotkb:NCVP2(gene name synonym)|uniprotkb:Non-structural RNA-binding protein 53(gene name synonym) psi-mi:h2a1h_human(display_long)|uniprotkb:H2AC12(gene name)|psi-mi:H2AC12(display_short)|uniprotkb:H2A-clustered histone 12(gene name synonym)|uniprotkb:HIST1H2AH(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:Histone H2A/s(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10915(rotp5)|taxid:10915("Rotavirus A (strain Pig/United States/OSU/1977 G5-P9[7]-I5-R1-C1-M1-A1-N1-T1-E1-H1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155890|imex:IM-17331-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002148(Non-structural RNA-binding protein 53, rotavirus)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0044163"(host cytoskeleton)|go:"GO:0046872"(metal ion binding) refseq:NP_542163.1|dip:DIP-61699N|ensembl:ENSG00000274997(gene)|ensembl:ENST00000377459(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OysqOFnFAKSWxRtIAcBkE5mUOnw10915 rogid:Oa322n+evy8Cu0E9cWTEdYwQPKM9606 intact-crc:341F49EB89C237BE|rigid:AvlhLqDhf+qNNGerq11PxOVoIsE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q84940 uniprotkb:P20671 intact:EBI-6148816|uniprotkb:Q85037 intact:EBI-4407441|uniprotkb:A0PK91|uniprotkb:P57754|uniprotkb:Q6FGY6|ensembl:ENSP00000341094 psi-mi:nsp1_rotp5(display_long)|uniprotkb:NCVP2(gene name synonym)|uniprotkb:Non-structural RNA-binding protein 53(gene name synonym) psi-mi:h2a1d_human(display_long)|uniprotkb:H2AC7(gene name)|psi-mi:H2AC7(display_short)|uniprotkb:H2AFG(gene name synonym)|uniprotkb:HIST1H2AD(gene name synonym)|uniprotkb:Histone H2A.3(gene name synonym)|uniprotkb:Histone H2A/g(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10915(rotp5)|taxid:10915("Rotavirus A (strain Pig/United States/OSU/1977 G5-P9[7]-I5-R1-C1-M1-A1-N1-T1-E1-H1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155890|imex:IM-17331-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002148(Non-structural RNA-binding protein 53, rotavirus)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0044163"(host cytoskeleton)|go:"GO:0046872"(metal ion binding) refseq:NP_066409.1|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000196866(gene)|ensembl:ENST00000341023(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:5GT3|rcsb pdb:6KBB|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OysqOFnFAKSWxRtIAcBkE5mUOnw10915 rogid:Geraq+dGw3pvAAhgzzXQnYxDOOw9606 intact-crc:341F49EB89C237BE|rigid:AvlhLqDhf+qNNGerq11PxOVoIsE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q84940 uniprotkb:P0C0S8 intact:EBI-6148816|uniprotkb:Q85037 intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538 psi-mi:nsp1_rotp5(display_long)|uniprotkb:NCVP2(gene name synonym)|uniprotkb:Non-structural RNA-binding protein 53(gene name synonym) psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10915(rotp5)|taxid:10915("Rotavirus A (strain Pig/United States/OSU/1977 G5-P9[7]-I5-R1-C1-M1-A1-N1-T1-E1-H1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155890|imex:IM-17331-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002148(Non-structural RNA-binding protein 53, rotavirus)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0044163"(host cytoskeleton)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OysqOFnFAKSWxRtIAcBkE5mUOnw10915 rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606 intact-crc:341F49EB89C237BE|rigid:AvlhLqDhf+qNNGerq11PxOVoIsE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q84940 uniprotkb:P04908 intact:EBI-6148816|uniprotkb:Q85037 intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842 psi-mi:nsp1_rotp5(display_long)|uniprotkb:NCVP2(gene name synonym)|uniprotkb:Non-structural RNA-binding protein 53(gene name synonym) psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10915(rotp5)|taxid:10915("Rotavirus A (strain Pig/United States/OSU/1977 G5-P9[7]-I5-R1-C1-M1-A1-N1-T1-E1-H1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155890|imex:IM-17331-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002148(Non-structural RNA-binding protein 53, rotavirus)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0044163"(host cytoskeleton)|go:"GO:0046872"(metal ion binding) refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OysqOFnFAKSWxRtIAcBkE5mUOnw10915 rogid:4Qno1mMYZB6FdNoojrzulWLVq849606 intact-crc:341F49EB89C237BE|rigid:AvlhLqDhf+qNNGerq11PxOVoIsE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q84940 uniprotkb:Q9UKB1 intact:EBI-6148816|uniprotkb:Q85037 intact:EBI-355189|uniprotkb:Q9P2S8|uniprotkb:Q9P2S9|uniprotkb:Q9Y4C6|uniprotkb:B2RC98|ensembl:ENSP00000265094 psi-mi:nsp1_rotp5(display_long)|uniprotkb:NCVP2(gene name synonym)|uniprotkb:Non-structural RNA-binding protein 53(gene name synonym) psi-mi:fbw1b_human(display_long)|uniprotkb:KIAA0696(gene name synonym)|uniprotkb:FBXW11(gene name)|psi-mi:FBXW11(display_short)|uniprotkb:BTRCP2(gene name synonym)|uniprotkb:FBW1B(gene name synonym)|uniprotkb:FBXW1B(gene name synonym)|uniprotkb:F-box/WD repeat-containing protein 1B(gene name synonym)|uniprotkb:F-box and WD repeats protein beta-TrCP2(gene name synonym)|uniprotkb:Homologous to Slimb protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10915(rotp5)|taxid:10915("Rotavirus A (strain Pig/United States/OSU/1977 G5-P9[7]-I5-R1-C1-M1-A1-N1-T1-E1-H1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155890|imex:IM-17331-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002148(Non-structural RNA-binding protein 53, rotavirus)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0044163"(host cytoskeleton)|go:"GO:0046872"(metal ion binding) refseq:NP_036432.2|refseq:NP_387448.2|refseq:NP_387449.2|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007097"(nuclear migration)|go:"GO:0007281"(germ cell development)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0005635"(nuclear envelope)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0070840"(dynein complex binding)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021977|interpro:IPR036047|interpro:IPR036322|mint:Q9UKB1|rcsb pdb:6WNX|reactome:R-HSA-1169091|reactome:R-HSA-202424|reactome:R-HSA-2565942|reactome:R-HSA-2871837|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-8951664|reactome:R-HSA-983168|go:"GO:0048511"(rhythmic process)|ensembl:ENSG00000072803(gene)|ensembl:ENST00000265094(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000776"(kinetochore)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|dip:DIP-27593N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OysqOFnFAKSWxRtIAcBkE5mUOnw10915 rogid:8wLc2Pt+mLfRsNwXOnjho+1A0u09606 intact-crc:341F49EB89C237BE|rigid:AvlhLqDhf+qNNGerq11PxOVoIsE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q84940 uniprotkb:Q9BTM1 intact:EBI-6148816|uniprotkb:Q85037 intact:EBI-4398590|uniprotkb:Q9NV63|ensembl:ENSP00000373730|ensembl:ENSP00000438553 psi-mi:nsp1_rotp5(display_long)|uniprotkb:NCVP2(gene name synonym)|uniprotkb:Non-structural RNA-binding protein 53(gene name synonym) psi-mi:h2aj_human(display_long)|uniprotkb:H2AJ(gene name)|psi-mi:H2AJ(display_short)|uniprotkb:H2AFJ(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10915(rotp5)|taxid:10915("Rotavirus A (strain Pig/United States/OSU/1977 G5-P9[7]-I5-R1-C1-M1-A1-N1-T1-E1-H1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155890|imex:IM-17331-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002148(Non-structural RNA-binding protein 53, rotavirus)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0044163"(host cytoskeleton)|go:"GO:0046872"(metal ion binding) refseq:NP_808760.1|ensembl:ENSG00000246705(gene)|ensembl:ENST00000389078(transcript)|ensembl:ENST00000544848(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:4EDU|rcsb pdb:6K60|rcsb pdb:6KVD|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-8939236 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OysqOFnFAKSWxRtIAcBkE5mUOnw10915 rogid:g6br63FeM17yJRfQI3GnmoM0vbc9606 intact-crc:341F49EB89C237BE|rigid:AvlhLqDhf+qNNGerq11PxOVoIsE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q84940 uniprotkb:P48741 intact:EBI-6148816|uniprotkb:Q85037 intact:EBI-877656|uniprotkb:P19790 psi-mi:nsp1_rotp5(display_long)|uniprotkb:NCVP2(gene name synonym)|uniprotkb:Non-structural RNA-binding protein 53(gene name synonym) psi-mi:hsp77_human(display_long)|uniprotkb:Heat shock 70 kDa protein B(gene name synonym)|uniprotkb:HSPA7(gene name)|psi-mi:HSPA7(display_short)|uniprotkb:HSP70B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10915(rotp5)|taxid:10915("Rotavirus A (strain Pig/United States/OSU/1977 G5-P9[7]-I5-R1-C1-M1-A1-N1-T1-E1-H1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155890|imex:IM-17331-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002148(Non-structural RNA-binding protein 53, rotavirus)|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0044163"(host cytoskeleton)|go:"GO:0046872"(metal ion binding) go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|reactome:R-HSA-3371453|interpro:IPR043129 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OysqOFnFAKSWxRtIAcBkE5mUOnw10915 rogid:ZXOhfWYdKdW1ek+VsKZyF/Zo84o9606 intact-crc:341F49EB89C237BE|rigid:AvlhLqDhf+qNNGerq11PxOVoIsE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P08393 uniprotkb:P12036 intact:EBI-6148881 intact:EBI-2880271|uniprotkb:Q9UQ14|uniprotkb:Q9UJS7|uniprotkb:Q96HF8|uniprotkb:B4DYY4|ensembl:ENSP00000311997 psi-mi:icp0_hhv11(display_long)|uniprotkb:ICP0(gene name)|psi-mi:ICP0(display_short)|uniprotkb:Alpha-0 protein(gene name synonym)|uniprotkb:IE110(gene name synonym)|uniprotkb:Immediate-early protein IE110(gene name synonym)|uniprotkb:Trans-acting transcriptional protein ICP0(gene name synonym)|uniprotkb:VMW110(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ICP0(gene name synonym) psi-mi:nfh_human(display_long)|uniprotkb:NEFH(gene name)|psi-mi:NEFH(display_short)|uniprotkb:KIAA0845(gene name synonym)|uniprotkb:NFH(gene name synonym)|uniprotkb:200 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament triplet H protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155953|imex:IM-17331-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137074.1|refseq:YP_009137133.1|mint:P08393|dip:DIP-42446N|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0019033"(viral tegument)|go:"GO:0019046"(release from viral latency)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0034340"(response to type I interferon)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0075342"(disruption by symbiont of host cell PML body)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:5C56|rcsb pdb:6JXU|rcsb pdb:6JXV|rcsb pdb:6JXW|rcsb pdb:6JXX refseq:NP_066554.2|ensembl:ENSG00000100285(gene)|ensembl:ENST00000310624(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005883"(neurofilament)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0061564"(axon development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR010790(Protein of unknown function DUF1388)|interpro:IPR018039|interpro:IPR033183|interpro:IPR039008|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:keAdk+TW9AFPk4Yn7Rm/mC65Kv010299 rogid:TXMrn6SWBHIYQY1loZfVvMo9PtU9606 intact-crc:DC604770A1DAC9F6|rigid:h3J/smkYIs3OWYinj7OxYJo8m4Y false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P08393 uniprotkb:Q93009 intact:EBI-6148881 intact:EBI-302474|uniprotkb:A6NMY8|intact:EBI-28988230|ensembl:ENSP00000343535|uniprotkb:B7Z815|uniprotkb:H0Y3G8 psi-mi:icp0_hhv11(display_long)|uniprotkb:ICP0(gene name)|psi-mi:ICP0(display_short)|uniprotkb:Alpha-0 protein(gene name synonym)|uniprotkb:IE110(gene name synonym)|uniprotkb:Immediate-early protein IE110(gene name synonym)|uniprotkb:Trans-acting transcriptional protein ICP0(gene name synonym)|uniprotkb:VMW110(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ICP0(gene name synonym) psi-mi:ubp7_human(display_long)|uniprotkb:USP7(gene name)|psi-mi:USP7(display_short)|uniprotkb:HAUSP(gene name synonym)|uniprotkb:Ubiquitin thioesterase 7(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 7(gene name synonym)|uniprotkb:Deubiquitinating enzyme 7(gene name synonym)|uniprotkb:Herpesvirus-associated ubiquitin-specific protease(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155953|imex:IM-17331-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137074.1|refseq:YP_009137133.1|mint:P08393|dip:DIP-42446N|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0019033"(viral tegument)|go:"GO:0019046"(release from viral latency)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0034340"(response to type I interferon)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039593"(suppression by virus of host exit from mitosis)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0042025"(host cell nucleus)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0075342"(disruption by symbiont of host cell PML body)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:5C56|rcsb pdb:6JXU|rcsb pdb:6JXV|rcsb pdb:6JXW|rcsb pdb:6JXX rcsb pdb:4PYZ|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:4YOC|rcsb pdb:4YSI|rcsb pdb:4Z96|rcsb pdb:4Z97|rcsb pdb:5C56|rcsb pdb:5C6D|rcsb pdb:5FWI|rcsb pdb:5GG4|rcsb pdb:5J7T|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5KYB|rcsb pdb:4M5X|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|interpro:IPR029346|interpro:IPR038765|mint:Q93009|rcsb pdb:1NB8|rcsb pdb:1NBF|rcsb pdb:1YY6|rcsb pdb:1YZE|rcsb pdb:2F1W|rcsb pdb:2F1X|rcsb pdb:2F1Y|rcsb pdb:2F1Z|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2FOP|rcsb pdb:2KVR|rcsb pdb:2XXN|rcsb pdb:2YLM|rcsb pdb:3MQR|rcsb pdb:3MQS|rcsb pdb:4JJQ|rcsb pdb:4KG9|rcsb pdb:4M5W|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050821"(protein stabilization)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904353"(regulation of telomere capping)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR018200|interpro:IPR024729|interpro:IPR028889|ensembl:ENSG00000187555(gene)|ensembl:ENST00000344836(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|rcsb pdb:5N9R|rcsb pdb:5N9T|rcsb pdb:5NGE|rcsb pdb:5NGF|rcsb pdb:5UQV|rcsb pdb:5UQX|rcsb pdb:5VS6|rcsb pdb:5VSB|rcsb pdb:5VSK|rcsb pdb:5WHC|rcsb pdb:6F5H|rcsb pdb:6M1K|rcsb pdb:6P5L|rcsb pdb:6VN2|rcsb pdb:6VN3|rcsb pdb:6VN4|rcsb pdb:6VN5|rcsb pdb:6VN6|rcsb pdb:7CM2|reactome:R-HSA-5689880|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804757|reactome:R-HSA-8866652|reactome:R-HSA-8948747|refseq:NP_001273386.1|refseq:NP_003461.2|refseq:NP_001308787.1|ensembl:ENSP00000343535|ensembl:ENST00000381886|ensembl:ENSP00000371310|dip:DIP-29053N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:keAdk+TW9AFPk4Yn7Rm/mC65Kv010299 rogid:V+PXXBRM2zwlGQaeFiyjaQ9yf+A9606 intact-crc:DC604770A1DAC9F6|rigid:h3J/smkYIs3OWYinj7OxYJo8m4Y false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:P07437 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:P34932 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-356933|uniprotkb:O95756|uniprotkb:Q2TAL4|uniprotkb:Q9BUK9|ensembl:ENSP00000302961 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:hsp74_human(display_long)|uniprotkb:HSPA4(gene name)|psi-mi:HSPA4(display_short)|uniprotkb:APG2(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-2(gene name synonym)|uniprotkb:HSP70RY(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) refseq:NP_002145.3|dip:DIP-460N|ensembl:ENSG00000170606(gene)|ensembl:ENST00000304858(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042052|interpro:IPR043129|mint:P34932|reactome:R-HSA-3371453 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:4OkTlG9p3IQQBYloiuHS8+t13TM9606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:Q709F0 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-2880718|ensembl:ENSP00000264990|uniprotkb:Q8WUT6|uniprotkb:Q08AF0|uniprotkb:Q658Y2|uniprotkb:Q658N9|uniprotkb:Q6ZND2|uniprotkb:Q9H9R3 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:acd11_human(display_long)|uniprotkb:ACAD11(gene name)|psi-mi:ACAD11(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000240303(gene)|ensembl:ENST00000264990(transcript)|go:"GO:0003995"(acyl-CoA dehydrogenase activity)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR002575(Aminoglycoside phosphotransferase)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|interpro:IPR041726|mint:Q709F0|rcsb pdb:2WBI|reactome:R-HSA-77289|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|refseq:NP_115545.3 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:Qknz1ZNcvX0q/3f5TuGQkJ6oHSk9606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:O95757 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-358652|uniprotkb:Q4W5M5|uniprotkb:Q8IWA2|uniprotkb:A2ICT2|ensembl:ENSP00000296464|ensembl:ENSP00000422482 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:hs74l_human(display_long)|uniprotkb:HSPA4L(gene name)|psi-mi:HSPA4L(display_short)|uniprotkb:APG1(gene name synonym)|uniprotkb:OSP94(gene name synonym)|uniprotkb:Osmotic stress protein 94(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-1(gene name synonym)|uniprotkb:Heat-shock protein family A member 4-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042708|interpro:IPR043129|mint:O95757|reactome:R-HSA-3371453|refseq:NP_055093.2|refseq:NP_001304310.1|refseq:NP_001304311.1|refseq:NP_001304312.1|go:"GO:0005634"(nucleus)|ensembl:ENSG00000164070(gene)|ensembl:ENST00000296464(transcript)|ensembl:ENST00000508776(transcript)|go:"GO:0005524"(ATP binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:6ZoMlI4t4A4u4YsQgrlcwAqjpi49606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:P07900 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|ensembl:ENSP00000216281|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) go:"GO:0009409"(response to cold)|go:"GO:0016020"(membrane)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|ensembl:ENST00000216281(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000080824(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043335"(protein unfolding)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1UY8|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2BYH|rcsb pdb:2VCJ|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3B24|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5LO1|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6CYH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7LSZ|rcsb pdb:7LT0|reactome:R-HSA-1227986|reactome:R-HSA-1236382|rcsb pdb:6TN4|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9665233|reactome:R-HSA-9664565|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3K99|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:3T0H|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:4YKZ|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|refseq:NP_001017963.2|refseq:NP_005339.3|dip:DIP-27595N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:P78406 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-724495|uniprotkb:O15306|uniprotkb:Q3SYL7|uniprotkb:Q5TCH8|uniprotkb:Q6V708|uniprotkb:Q9H100|uniprotkb:Q9NQM6|ensembl:ENSP00000360286|ensembl:ENSP00000379181|ensembl:ENSP00000379182|uniprotkb:A8K882 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:rae1l_human(display_long)|uniprotkb:mRNA-associated protein mrnp 41(gene name synonym)|uniprotkb:Rae1 protein homolog(gene name synonym)|uniprotkb:RAE1(gene name)|psi-mi:RAE1(display_short)|uniprotkb:MRNP41(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) refseq:NP_001015885.1|refseq:NP_003601.1|ensembl:ENSG00000101146(gene)|ensembl:ENST00000371242(transcript)|ensembl:ENST00000395840(transcript)|ensembl:ENST00000395841(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037631|mint:P78406|rcsb pdb:3MMY|rcsb pdb:4OWR|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|interpro:IPR019775|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|refseq:XP_011527390.1|refseq:XP_011527391.1|refseq:XP_005260639.2|dip:DIP-41063N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:JK4Y5p3WUcHFXBXyhhqCnDnG49c9606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:P08238 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:wOsW7C10v2oMsM+REE38K6PAan09606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:P78371 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:Q13509 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-350989|uniprotkb:Q9BTZ0|uniprotkb:Q9BW10|ensembl:ENSP00000320295|uniprotkb:A8K854 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:tbb3_human(display_long)|uniprotkb:TUBB3(gene name)|psi-mi:TUBB3(display_short)|uniprotkb:TUBB4(gene name synonym)|uniprotkb:Tubulin beta-III(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) refseq:NP_001184110.1|refseq:NP_006077.2|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-6807878|ensembl:ENSG00000258947(gene)|ensembl:ENST00000315491(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007411"(axon guidance)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q13509|rcsb pdb:5IJ9|rcsb pdb:5JCO|rcsb pdb:6E7B|rcsb pdb:6S8L|rcsb pdb:6WSL|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|rcsb pdb:5IJ0|dip:DIP-31505N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:A69G+idFQmuzkmCsGyBtGVqglSo9606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:P52948 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-295727|uniprotkb:Q8IUT2|uniprotkb:Q8WYB0|uniprotkb:Q96E54|uniprotkb:Q9H3Q4|uniprotkb:Q9NT02|uniprotkb:Q9UF57|uniprotkb:Q9UHX0|uniprotkb:Q9Y6J4|uniprotkb:Q9Y6J5|ensembl:ENSP00000352091 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:nup98_human(display_long)|uniprotkb:NUP98(gene name)|psi-mi:NUP98(display_short)|uniprotkb:ADAR2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) refseq:NP_005378.4|refseq:NP_057404.2|refseq:NP_624357.1|refseq:NP_624358.2|ensembl:ENST00000324932|ensembl:ENSP00000316032|ensembl:ENST00000355260|ensembl:ENSP00000347404|ensembl:ENSP00000352091|ensembl:ENST00000397004|ensembl:ENSP00000380199|ensembl:ENST00000397007|ensembl:ENSP00000380202|dip:DIP-32484N|ensembl:ENSG00000110713(gene)|ensembl:ENST00000359171(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005215"(transporter activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|mint:P52948|rcsb pdb:1KO6|rcsb pdb:2Q5X|rcsb pdb:2Q5Y|rcsb pdb:3MMY|rcsb pdb:4OWR|rcsb pdb:5A9Q|rcsb pdb:6BZM|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:aW9NaKgLZti0wLEiVQogGukcWdE9606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:P50991 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:Q9Y4L1 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-1054186|uniprotkb:Q2I204|uniprotkb:Q53H25|uniprotkb:B7Z909|uniprotkb:A8C1Z0|ensembl:ENSP00000480150|ensembl:ENSP00000486825 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:hyou1_human(display_long)|uniprotkb:150 kDa oxygen-regulated protein(gene name synonym)|uniprotkb:GRP170(gene name synonym)|uniprotkb:HYOU1(gene name)|psi-mi:HYOU1(display_short)|uniprotkb:ORP150(gene name synonym)|uniprotkb:170 kDa glucose-regulated protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) refseq:NP_001124463.1|refseq:NP_006380.1|refseq:XP_016872585.1|refseq:XP_016872586.1|ensembl:ENSG00000149428(gene)|ensembl:ENSG00000280682(gene)|ensembl:ENST00000617285(transcript)|ensembl:ENST00000630669(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005925"(focal adhesion)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:1903382"(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:Q9Y4L1|reactome:R-HSA-3000484|reactome:R-HSA-381038|go:"GO:0005790"(smooth endoplasmic reticulum) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:xqSFRaiiHJLNVqgh87tHx9lfnS49606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:Q9UK99 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-2509901|uniprotkb:B3KY16|uniprotkb:D3DR05|uniprotkb:Q9H0V2|uniprotkb:Q86X90|uniprotkb:Q9NUX2|ensembl:ENSP00000265651 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:fbx3_human(display_long)|uniprotkb:FBXO3(gene name)|psi-mi:FBXO3(display_short)|uniprotkb:FBX3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) refseq:NP_036307.2|refseq:NP_208385.1|dip:DIP-53688N|ensembl:ENSG00000110429(gene)|ensembl:ENST00000265651(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR007474(ApaG)|interpro:IPR018958|interpro:IPR028388|interpro:IPR036047|interpro:IPR036767|interpro:IPR037883|rcsb pdb:5HDW - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:zQB8ig3s51tXN81NtMrou84Rv6I9606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:Q71U36 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:P49368 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:P48643 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:P54652 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-356991|uniprotkb:Q15508|uniprotkb:Q53XM3|uniprotkb:Q9UE78|ensembl:ENSP00000247207|ensembl:ENSP00000378199 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:hsp72_human(display_long)|uniprotkb:HSPA2(gene name)|psi-mi:HSPA2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) refseq:NP_068814.2|ensembl:ENSG00000126803(gene)|ensembl:ENST00000247207(transcript)|ensembl:ENST00000394709(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0036128"(CatSper complex)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0048156"(tau protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051861"(glycolipid binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0072562"(blood microparticle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P54652|rcsb pdb:3I33|rcsb pdb:4FSV|rcsb pdb:5FPD|rcsb pdb:5FPE|rcsb pdb:5FPM|rcsb pdb:5FPN|reactome:R-HSA-1221632|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:U+fdNfdxAWBQxDwSx0plk/iIBpM9606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:P11021 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:Q92598 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-356829|uniprotkb:O95739|uniprotkb:Q5TBM6|uniprotkb:Q5TBM8|uniprotkb:Q9UPC4|uniprotkb:Q5TBM7|intact:EBI-2859494|uniprotkb:B4DYH1|ensembl:ENSP00000318687 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:hs105_human(display_long)|uniprotkb:HSPH1(gene name)|psi-mi:HSPH1(display_short)|uniprotkb:HSP105(gene name synonym)|uniprotkb:HSP110(gene name synonym)|uniprotkb:KIAA0201(gene name synonym)|uniprotkb:Heat shock 110 kDa protein(gene name synonym)|uniprotkb:Antigen NY-CO-25(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) refseq:NP_001273432.1|refseq:NP_001273433.1|refseq:NP_001273434.1|refseq:NP_006635.2|ensembl:ENSG00000120694(gene)|ensembl:ENST00000320027(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051135"(positive regulation of NK T cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042053|interpro:IPR043129|mint:Q92598|rcsb pdb:6GFA|reactome:R-HSA-3000484|reactome:R-HSA-3371453 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:FSdvp2KDHLmNpceRJ9HLY5IBfQA9606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:P68371 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:Q16698 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-2554876|uniprotkb:B7Z6B8|uniprotkb:Q93085|uniprotkb:Q2M304|ensembl:ENSP00000220764|intact:EBI-10969978 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:decr_human(display_long)|uniprotkb:DECR(gene name synonym)|uniprotkb:2,4-dienoyl-CoA reductase [NADPH](gene name synonym)|uniprotkb:DECR1(gene name)|psi-mi:DECR1(display_short)|uniprotkb:SDR18C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 18C member 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) refseq:NP_001350.1|ensembl:ENSG00000104325(gene)|ensembl:ENST00000220764(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0008670"("2,4-dienoyl-CoA reductase (NADPH) activity")|go:"GO:0042802"(identical protein binding)|go:"GO:0070402"(NADPH binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902494"(catalytic complex)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|mint:Q16698|rcsb pdb:1W6U|rcsb pdb:1W73|rcsb pdb:1W8D|reactome:R-HSA-77288|interpro:IPR036291|refseq:NP_001317504.1|refseq:XP_016868636.1|refseq:XP_016868637.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:l/8jxdd4pqUIUV2eIThvXTd66yE9606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:Q9BQE3 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:P22061 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-353343|uniprotkb:Q14661|uniprotkb:Q16556|uniprotkb:Q5VYC1|uniprotkb:Q5VYC2|uniprotkb:Q93061|uniprotkb:Q96II9|uniprotkb:Q99625|uniprotkb:Q9BQV7|uniprotkb:Q9BQV8|uniprotkb:Q9NP03|uniprotkb:A8K109|intact:EBI-2551555|uniprotkb:J3KP72|ensembl:ENSP00000356348|ensembl:ENSP00000420813 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:pimt_human(display_long)|uniprotkb:PCMT1(gene name)|psi-mi:PCMT1(display_short)|uniprotkb:Protein-beta-aspartate methyltransferase(gene name synonym)|uniprotkb:Protein L-isoaspartyl/D-aspartyl methyltransferase(gene name synonym)|uniprotkb:L-isoaspartyl protein carboxyl methyltransferase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) refseq:NP_001238978.1|refseq:NP_001238982.1|ensembl:ENSG00000120265(gene)|ensembl:ENST00000367378(transcript)|ensembl:ENST00000464889(transcript)|go:"GO:0004719"("protein-L-isoaspartate (D-aspartate) O-methyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0030091"(protein repair)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000682("Protein-L-isoaspartate(D-aspartate) O-methyltransferase")|interpro:IPR029063|mint:P22061|rcsb pdb:1I1N|rcsb pdb:1KR5|reactome:R-HSA-5676934|refseq:NP_005380.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:wfsjVloc3sqDMXlvFAXQI6Fjilw9606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:P04350 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-355007|uniprotkb:B3KQP4|uniprotkb:Q969E5|ensembl:ENSP00000264071 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:tbb4a_human(display_long)|uniprotkb:TUBB4A(gene name)|psi-mi:TUBB4A(display_short)|uniprotkb:TUBB4(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:Tubulin 5 beta(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) refseq:NP_006078.2|ensembl:ENSG00000104833(gene)|ensembl:ENST00000264071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0033269"(internode region of axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P04350|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001276052.1|refseq:NP_001276056.1|refseq:NP_001276058.1|refseq:NP_001276059.1|refseq:NP_001276060.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:mMveBNZkQs2x0dyHm/ghVWBe4/49606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:Q01968 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-6148898|uniprotkb:O60800|uniprotkb:Q15684|uniprotkb:A6NKI1|uniprotkb:Q9UMA5|uniprotkb:Q4VY09|uniprotkb:Q5JQF2|uniprotkb:A8KAP2|uniprotkb:Q15774|uniprotkb:Q5JQF1|uniprotkb:Q9UJG5|uniprotkb:Q4VY10|uniprotkb:B7ZLX2|ensembl:ENSP00000360154 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:ocrl_human(display_long)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)|uniprotkb:OCRL(gene name)|psi-mi:OCRL(display_short)|uniprotkb:Lowe oculocerebrorenal syndrome protein(gene name synonym)|uniprotkb:OCRL1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) refseq:NP_000267.2|refseq:NP_001578.2|dip:DIP-45092N|ensembl:ENSG00000122126(gene)|ensembl:ENST00000371113(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0004445"(inositol-polyphosphate 5-phosphatase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005795"(Golgi stack)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034485"(phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0034596"(phosphatidylinositol phosphate 4-phosphatase activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0052658"(inositol-1,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0052659"(inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity)|go:"GO:0052745"(inositol phosphate phosphatase activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061024"(membrane organization)|interpro:IPR000198(RhoGAP)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031995|interpro:IPR036691|interpro:IPR037787|interpro:IPR037793|mint:Q01968|rcsb pdb:2KIE|rcsb pdb:2QV2|rcsb pdb:3QBT|rcsb pdb:3QIS|rcsb pdb:4CMN|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-1855183|reactome:R-HSA-1855204|reactome:R-HSA-432722|reactome:R-HSA-8856828|reactome:R-HSA-9013409|reactome:R-HSA-9013423 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:vbBQzhjgvm07+wOJkWgz+dyEBI49606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21698 uniprotkb:P50990 intact:EBI-6148916|uniprotkb:A2SZX2 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:nss_rvfvz(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11589(rvfv)|taxid:11589("Rift valley fever virus (strain ZH-548 M12)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6155965|imex:IM-17331-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:2N0Y|interpro:IPR024376|rcsb pdb:5OOO|refseq:YP_003848706.1|interpro:IPR039434|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039602"(suppression by virus of host transcription initiation from RNA polymerase II promoter)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039657"(suppression by virus of host gene expression)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0042025"(host cell nucleus) refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/07/08 rogid:y4GFIj292QlcGalELSMF4riYylw11589 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 intact-crc:D5335060E693A4E2|rigid:etVV0LqLVfbbxvYfDRyXM6m6vdc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q80A33 uniprotkb:Q02539 intact:EBI-6149005 intact:EBI-932603|uniprotkb:Q3MJ34|ensembl:ENSP00000244573 psi-mi:ml_thogv(display_long)|uniprotkb:Segment 6(locus name) psi-mi:h11_human(display_long)|uniprotkb:H1-1(gene name)|psi-mi:H1-1(display_short)|uniprotkb:H1F1(gene name synonym)|uniprotkb:HIST1H1A(gene name synonym)|uniprotkb:Histone H1a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:126796(tho)|taxid:126796("Thogoto virus (isolate SiAr 126)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156049|imex:IM-17331-24 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_145805.1|interpro:IPR035212|rcsb pdb:5I5N|rcsb pdb:5I5O|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity) refseq:NP_005316.1|ensembl:ENSG00000124610(gene)|ensembl:ENST00000244573(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q02539|reactome:R-HSA-140342|reactome:R-HSA-2559584 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:lORtj9qnikgXZ6k/ASwXxDGMNRE126796 rogid:4u8P8jFM3onWx43+SxL320urjhk9606 intact-crc:B1EFF507BF3D8734|rigid:eJ7iRdTobpoFWMrIzVLMjbdjeog false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q80A33 uniprotkb:O75808 intact:EBI-6149005 intact:EBI-6149008|uniprotkb:Q9BUW0|uniprotkb:B1B1M4|uniprotkb:Q8WTY9|uniprotkb:Q2KHS2|ensembl:ENSP00000219611 psi-mi:ml_thogv(display_long)|uniprotkb:Segment 6(locus name) psi-mi:can15_human(display_long)|uniprotkb:CAPN15(gene name)|psi-mi:CAPN15(display_short)|uniprotkb:SOLH(gene name synonym)|uniprotkb:Small optic lobes homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:126796(tho)|taxid:126796("Thogoto virus (isolate SiAr 126)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156049|imex:IM-17331-24 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_145805.1|interpro:IPR035212|rcsb pdb:5I5N|rcsb pdb:5I5O|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity) refseq:NP_005623.1|ensembl:ENSG00000103326(gene)|ensembl:ENST00000219611(transcript)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006508"(proteolysis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR022684|interpro:IPR036443|interpro:IPR038765|reactome:R-HSA-1474228 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:lORtj9qnikgXZ6k/ASwXxDGMNRE126796 rogid:GbitF0RjGDdGa0p1IrmWmLfpjfI9606 intact-crc:B1EFF507BF3D8734|rigid:eJ7iRdTobpoFWMrIzVLMjbdjeog false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q80A33 uniprotkb:Q00403 intact:EBI-6149005 intact:EBI-389564|uniprotkb:A8K1A7|uniprotkb:Q5JS30|ensembl:ENSP00000359531 psi-mi:ml_thogv(display_long)|uniprotkb:Segment 6(locus name) psi-mi:tf2b_human(display_long)|uniprotkb:GTF2B(gene name)|psi-mi:GTF2B(display_short)|uniprotkb:TF2B(gene name synonym)|uniprotkb:TFIIB(gene name synonym)|uniprotkb:General transcription factor TFIIB(gene name synonym)|uniprotkb:S300-II(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:126796(tho)|taxid:126796("Thogoto virus (isolate SiAr 126)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156049|imex:IM-17331-24 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_145805.1|interpro:IPR035212|rcsb pdb:5I5N|rcsb pdb:5I5O|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity) refseq:NP_001505.1|ensembl:ENSG00000137947(gene)|ensembl:ENST00000370500(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001174"(transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005694"(chromosome)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006473"(protein acetylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019083"(viral transcription)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1990114"(RNA polymerase II core complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000812(Transcription factor TFIIB related)|interpro:IPR013137(Zinc finger, TFIIB-type)|interpro:IPR013150(Transcription factor TFIIB, cyclin-related)|interpro:IPR013763(Cyclin-related)|interpro:IPR023486|interpro:IPR036915|mint:Q00403|rcsb pdb:1C9B|rcsb pdb:1DL6|rcsb pdb:1RLY|rcsb pdb:1RO4|rcsb pdb:1TFB|rcsb pdb:1VOL|rcsb pdb:2PHG|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5WH1|rcsb pdb:6O9L|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6807505|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|dip:DIP-1077N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:lORtj9qnikgXZ6k/ASwXxDGMNRE126796 rogid:mVGHi0jBibSFHpBrVTGHnRm4gXw9606 intact-crc:B1EFF507BF3D8734|rigid:eJ7iRdTobpoFWMrIzVLMjbdjeog false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q80A33 uniprotkb:P22492 intact:EBI-6149005 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 psi-mi:ml_thogv(display_long)|uniprotkb:Segment 6(locus name) psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:126796(tho)|taxid:126796("Thogoto virus (isolate SiAr 126)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156049|imex:IM-17331-24 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_145805.1|interpro:IPR035212|rcsb pdb:5I5N|rcsb pdb:5I5O|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:lORtj9qnikgXZ6k/ASwXxDGMNRE126796 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 intact-crc:B1EFF507BF3D8734|rigid:eJ7iRdTobpoFWMrIzVLMjbdjeog false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q80A33 uniprotkb:Q562R1 intact:EBI-6149005 intact:EBI-1773495|uniprotkb:Q562R2|uniprotkb:Q562S9|uniprotkb:Q562X8|uniprotkb:B2RPJ1|ensembl:ENSP00000416706 psi-mi:ml_thogv(display_long)|uniprotkb:Segment 6(locus name) psi-mi:actbl_human(display_long)|uniprotkb:ACTBL2(gene name)|psi-mi:ACTBL2(display_short)|uniprotkb:Kappa-actin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:126796(tho)|taxid:126796("Thogoto virus (isolate SiAr 126)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156049|imex:IM-17331-24 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_145805.1|interpro:IPR035212|rcsb pdb:5I5N|rcsb pdb:5I5O|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity) refseq:NP_001017992.1|ensembl:ENSG00000169067(gene)|ensembl:ENST00000423391(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0007409"(axonogenesis)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0045202"(synapse)|go:"GO:0048870"(cell motility)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:Q562R1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:lORtj9qnikgXZ6k/ASwXxDGMNRE126796 rogid:GTzKP5YRJGH8ocAJW0WEsdQFEdc9606 intact-crc:B1EFF507BF3D8734|rigid:eJ7iRdTobpoFWMrIzVLMjbdjeog false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P14254 uniprotkb:P63151 intact:EBI-6149039|uniprotkb:P14258|uniprotkb:P14257|uniprotkb:Q88447|uniprotkb:Q88446 intact:EBI-1048931|uniprotkb:P50409|uniprotkb:Q00007|uniprotkb:B2RBU8|intact:EBI-2556013|uniprotkb:B4E1T7|ensembl:ENSP00000370113 psi-mi:c_sendf(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:2aba_human(display_long)|uniprotkb:PPP2R2A(gene name)|psi-mi:PPP2R2A(display_short)|uniprotkb:PP2A subunit B isoform alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11195(sendf)|taxid:11195("Sendai virus (strain Fushimi)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156070|imex:IM-17331-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002608(Paramyxovirus non-structural protein c)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity) refseq:NP_001171062.1|refseq:NP_002708.1|ensembl:ENSG00000221914(gene)|ensembl:ENST00000380737(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043278"(response to morphine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:P63151|rcsb pdb:3DW8|reactome:R-HSA-2995383|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-975957|dip:DIP-29398N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:esSYxd93gDbL43gtn4U7SdizU6811195 rogid:evS6klM2alZXtMthVsshKkrNgiA9606 intact-crc:F25205DCAAD7EF57|rigid:Ec+HsAkYEaA7ZyYx6dmDk7j1dPE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P14254 uniprotkb:P42224 intact:EBI-6149039|uniprotkb:P14258|uniprotkb:P14257|uniprotkb:Q88447|uniprotkb:Q88446 intact:EBI-1057697|uniprotkb:Q53S88|uniprotkb:Q53XW4|uniprotkb:B2RCA0|uniprotkb:Q9UDL5|uniprotkb:A8K989|uniprotkb:D2KFR8|uniprotkb:Q68D00|uniprotkb:D3DPI7|ensembl:ENSP00000354394|ensembl:ENSP00000386244|ensembl:ENSP00000388240|ensembl:ENSP00000438703 psi-mi:c_sendf(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:stat1_human(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)|uniprotkb:Transcription factor ISGF-3 components p91/p84(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11195(sendf)|taxid:11195("Sendai virus (strain Fushimi)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156070|imex:IM-17331-25 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002608(Paramyxovirus non-structural protein c)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity) refseq:NP_009330.1|refseq:NP_644671.1|rcsb pdb:1YVL|rcsb pdb:2KA6|rcsb pdb:3WWT|reactome:R-HSA-1059683|reactome:R-HSA-1169408|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8939902|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9013508|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-909733|rcsb pdb:1BF5|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-912694|refseq:XP_006712781.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016922"(nuclear receptor binding)|ensembl:ENSG00000115415(gene)|ensembl:ENST00000361099(transcript)|ensembl:ENST00000409465(transcript)|ensembl:ENST00000415035(transcript)|ensembl:ENST00000540176(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051607"(defense response to virus)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0061326"(renal tubule development)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022752|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|interpro:IPR035859|interpro:IPR036535|interpro:IPR036860|interpro:IPR038295|mint:P42224|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042393"(histone binding)|dip:DIP-46140N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:esSYxd93gDbL43gtn4U7SdizU6811195 rogid:a2ZnhdFZkctbjaXLpsYNJ3q5Cv49606 intact-crc:F25205DCAAD7EF57|rigid:Ec+HsAkYEaA7ZyYx6dmDk7j1dPE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O55779 uniprotkb:O95819 intact:EBI-6149058 intact:EBI-2511133|intact:EBI-28985706|ensembl:ENSP00000314363|uniprotkb:Q9NST7|uniprotkb:O75172|uniprotkb:E7ESS2 psi-mi:c_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:m4k4_human(display_long)|uniprotkb:MAP4K4(gene name)|psi-mi:MAP4K4(display_short)|uniprotkb:HGK(gene name synonym)|uniprotkb:KIAA0687(gene name synonym)|uniprotkb:NIK(gene name synonym)|uniprotkb:MAPK/ERK kinase kinase kinase 4(gene name synonym)|uniprotkb:HPK/GCK-like kinase HGK(gene name synonym)|uniprotkb:Nck-interacting kinase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156082|imex:IM-17331-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031812|refseq:NP_047109.1|go:"GO:0030683"(mitigation of host immune response by virus) refseq:NP_663719.2|ensembl:ENST00000347699(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008017"(microtubule binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032014"(positive regulation of ARF protein signal transduction)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070571"(negative regulation of neuron projection regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O95819|rcsb pdb:4OBO|rcsb pdb:4OBP|rcsb pdb:4OBQ|rcsb pdb:4RVT|rcsb pdb:4U3Y|rcsb pdb:4U3Z|rcsb pdb:4U40|rcsb pdb:4U41|rcsb pdb:4U42|rcsb pdb:4U43|rcsb pdb:4U44|rcsb pdb:4U45|rcsb pdb:4ZK5|rcsb pdb:4ZP5|rcsb pdb:5DI1|rcsb pdb:5J95|rcsb pdb:5W5Q|reactome:R-HSA-2559580|ensembl:ENSG00000071054(gene)|refseq:NP_001229488.1|refseq:NP_004825.3|refseq:NP_663720.1|ensembl:ENSP00000314363|ensembl:ENST00000350878|ensembl:ENSP00000343658|ensembl:ENST00000634702|ensembl:ENSP00000489579 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OXHbTyzPlQvbZsrnzdD07pGfhXY928303 rogid:wEXGp6vM4HhwldyeQJKvEdilMpQ9606 intact-crc:D595F25659E3E0D8|rigid:M+3/o9G3Fle1Y505n5bRHtKBagM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O55779 uniprotkb:Q99816 intact:EBI-6149058 intact:EBI-346882|uniprotkb:Q9BUM5|ensembl:ENSP00000251968 psi-mi:c_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:ts101_human(display_long)|uniprotkb:TSG101(gene name)|psi-mi:TSG101(display_short)|uniprotkb:ESCRT-I complex subunit TSG101(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156082|imex:IM-17331-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031812|refseq:NP_047109.1|go:"GO:0030683"(mitigation of host immune response by virus) refseq:NP_006283.1|ensembl:ENSP00000251968|dip:DIP-31809N|ensembl:ENSG00000074319(gene)|ensembl:ENST00000251968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006858"(extracellular transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046755"(viral budding)|go:"GO:0046790"(virion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090543"(Flemming body)|go:"GO:0097352"(autophagosome maturation)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1990182"(exosomal secretion)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|mint:Q99816|rcsb pdb:1KPP|rcsb pdb:1KPQ|rcsb pdb:1M4P|rcsb pdb:1M4Q|rcsb pdb:1S1Q|rcsb pdb:2F0R|rcsb pdb:3IV1|rcsb pdb:3OBQ|rcsb pdb:3OBS|rcsb pdb:3OBU|rcsb pdb:3OBX|rcsb pdb:3P9G|rcsb pdb:3P9H|rcsb pdb:4EJE|rcsb pdb:4YC1|rcsb pdb:4ZNY|rcsb pdb:5VKG|rcsb pdb:6UD0|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OXHbTyzPlQvbZsrnzdD07pGfhXY928303 rogid:hoi+Pw0Rr3wL/1ePQINUq3BmSFI9606 intact-crc:D595F25659E3E0D8|rigid:M+3/o9G3Fle1Y505n5bRHtKBagM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O55779 uniprotkb:P62269 intact:EBI-6149058 intact:EBI-352451|ensembl:ENSP00000211372|ensembl:ENSP00000393241|ensembl:ENSP00000403175|ensembl:ENSP00000412583|ensembl:ENSP00000416110|uniprotkb:P25232|uniprotkb:Q6IPF8|uniprotkb:Q5SUJ3 psi-mi:c_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:rs18_human(display_long)|uniprotkb:RPS18(gene name)|psi-mi:RPS18(display_short)|uniprotkb:D6S218E(gene name synonym)|uniprotkb:Ke-3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS13(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156082|imex:IM-17331-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031812|refseq:NP_047109.1|go:"GO:0030683"(mitigation of host immune response by virus) refseq:NP_072045.1|ensembl:ENSG00000096150(gene)|ensembl:ENSG00000223367(gene)|ensembl:ENSG00000226225(gene)|ensembl:ENSG00000231500(gene)|ensembl:ENSG00000235650(gene)|ensembl:ENST00000211372(transcript)|ensembl:ENST00000434122(transcript)|ensembl:ENST00000439602(transcript)|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENST00000454021(transcript)|ensembl:ENST00000457341(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001892(Ribosomal protein S13)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR018269|interpro:IPR027437|mint:P62269|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|dip:DIP-32892N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OXHbTyzPlQvbZsrnzdD07pGfhXY928303 rogid:yOHgKM/BuvgGdqp1OEVPeuiABg89606 intact-crc:D595F25659E3E0D8|rigid:M+3/o9G3Fle1Y505n5bRHtKBagM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O55779 uniprotkb:Q71U36 intact:EBI-6149058 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:c_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156082|imex:IM-17331-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031812|refseq:NP_047109.1|go:"GO:0030683"(mitigation of host immune response by virus) refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OXHbTyzPlQvbZsrnzdD07pGfhXY928303 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 intact-crc:D595F25659E3E0D8|rigid:M+3/o9G3Fle1Y505n5bRHtKBagM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O55779 uniprotkb:Q96EY5 intact:EBI-6149058 intact:EBI-4290865|uniprotkb:Q96I18|ensembl:ENSP00000324810|ensembl:ENSP00000444653 psi-mi:c_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:mb12a_human(display_long)|uniprotkb:MVB12A(gene name)|psi-mi:MVB12A(display_short)|uniprotkb:CFBP(gene name synonym)|uniprotkb:CIN85/CD2AP family-binding protein(gene name synonym)|uniprotkb:ESCRT-I complex subunit MVB12A(gene name synonym)|uniprotkb:FAM125A(gene name synonym)|uniprotkb:Protein FAM125A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156082|imex:IM-17331-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031812|refseq:NP_047109.1|go:"GO:0030683"(mitigation of host immune response by virus) refseq:NP_612410.1|ensembl:ENSG00000141971(gene)|ensembl:ENST00000317040(transcript)|ensembl:ENST00000543795(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008289"(lipid binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019075"(virus maturation)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0046755"(viral budding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR018798|interpro:IPR023340|interpro:IPR023341|interpro:IPR040335|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OXHbTyzPlQvbZsrnzdD07pGfhXY928303 rogid:KkN1uSvXWKl0oOX7GhP44l2MpBY9606 intact-crc:D595F25659E3E0D8|rigid:M+3/o9G3Fle1Y505n5bRHtKBagM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O55779 uniprotkb:Q9UK41 intact:EBI-6149058 intact:EBI-727424|uniprotkb:Q86VK0|ensembl:ENSP00000292510|ensembl:ENSP00000434064|ensembl:ENSP00000496519|ensembl:ENSP00000496693 psi-mi:c_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:vps28_human(display_long)|uniprotkb:VPS28(gene name)|psi-mi:VPS28(display_short)|uniprotkb:ESCRT-I complex subunit VPS28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156082|imex:IM-17331-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031812|refseq:NP_047109.1|go:"GO:0030683"(mitigation of host immune response by virus) refseq:NP_057292.1|refseq:NP_898880.1|ensembl:ENSG00000160948(gene)|ensembl:ENSG00000285339(gene)|ensembl:ENST00000292510(transcript)|ensembl:ENST00000526054(transcript)|ensembl:ENST00000642867(transcript)|ensembl:ENST00000643186(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000397"(positive regulation of ubiquitin-dependent endocytosis)|interpro:IPR007143(Vacuolar protein sorting-associated, VPS28)|interpro:IPR017898|interpro:IPR017899|interpro:IPR037202|interpro:IPR037206|interpro:IPR038358|mint:Q9UK41|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OXHbTyzPlQvbZsrnzdD07pGfhXY928303 rogid:GUcc7bRf1LaLklAYVLEHRSihPjA9606 intact-crc:D595F25659E3E0D8|rigid:M+3/o9G3Fle1Y505n5bRHtKBagM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O55779 uniprotkb:Q9H9H4 intact:EBI-6149058 intact:EBI-4400866|intact:EBI-28975719|ensembl:ENSP00000267202 psi-mi:c_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:vp37b_human(display_long)|uniprotkb:VPS37B(gene name)|psi-mi:VPS37B(display_short)|uniprotkb:ESCRT-I complex subunit VPS37B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156082|imex:IM-17331-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031812|refseq:NP_047109.1|go:"GO:0030683"(mitigation of host immune response by virus) ensembl:ENSP00000267202|refseq:NP_078943.1|ensembl:ENSG00000139722(gene)|ensembl:ENST00000267202(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0010008"(endosome membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0031902"(late endosome membrane)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|interpro:IPR009851(Modifier of rudimentary, Modr)|interpro:IPR029012|interpro:IPR037202|mint:Q9H9H4|rcsb pdb:6VME|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OXHbTyzPlQvbZsrnzdD07pGfhXY928303 rogid:dj398+zsegXf+gk9OiSeZAVlmqk9606 intact-crc:D595F25659E3E0D8|rigid:M+3/o9G3Fle1Y505n5bRHtKBagM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O55779 uniprotkb:Q9BQE3 intact:EBI-6149058 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:c_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156082|imex:IM-17331-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031812|refseq:NP_047109.1|go:"GO:0030683"(mitigation of host immune response by virus) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OXHbTyzPlQvbZsrnzdD07pGfhXY928303 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:D595F25659E3E0D8|rigid:M+3/o9G3Fle1Y505n5bRHtKBagM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O55779 uniprotkb:Q9H7P6 intact:EBI-6149058 intact:EBI-6149062|uniprotkb:Q8N6S7|ensembl:ENSP00000354772 psi-mi:c_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:mb12b_human(display_long)|uniprotkb:MVB12B(gene name)|psi-mi:MVB12B(display_short)|uniprotkb:C9orf28(gene name synonym)|uniprotkb:ESCRT-I complex subunit MVB12B(gene name synonym)|uniprotkb:FAM125B(gene name synonym)|uniprotkb:Protein FAM125B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156082|imex:IM-17331-26 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR031812|refseq:NP_047109.1|go:"GO:0030683"(mitigation of host immune response by virus) refseq:NP_001011703.1|refseq:NP_258257.1|ensembl:ENSG00000196814(gene)|ensembl:ENST00000361171(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019075"(virus maturation)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0046755"(viral budding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR018798|interpro:IPR023340|interpro:IPR023341|interpro:IPR040297|rcsb pdb:3TOW|reactome:R-HSA-162588|reactome:R-HSA-174490|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:OXHbTyzPlQvbZsrnzdD07pGfhXY928303 rogid:uJuscJlXb5onvcNpR44I3bsmjLA9606 intact-crc:D595F25659E3E0D8|rigid:M+3/o9G3Fle1Y505n5bRHtKBagM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:P22532 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-2267183|uniprotkb:A8K5K2|uniprotkb:Q5T523|uniprotkb:Q96RM3|uniprotkb:A4QN03|uniprotkb:D3DV33|ensembl:ENSP00000353542|ensembl:ENSP00000357745|ensembl:ENSP00000357746|ensembl:ENSP00000357747 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:spr2d_human(display_long)|uniprotkb:SPRR2D(gene name)|psi-mi:SPRR2D(display_short)|uniprotkb:Small proline-rich protein II(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:XP_016857664.1|refseq:NP_008876.3|ensembl:ENSG00000163216(gene)|ensembl:ENST00000360379(transcript)|ensembl:ENST00000368756(transcript)|ensembl:ENST00000368757(transcript)|ensembl:ENST00000368758(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0031424"(keratinization)|interpro:IPR029142|mint:P22532|reactome:R-HSA-6809371 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:lenGTh/4TMFWnOff3clJuq6/IeU9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:Q02539 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-932603|uniprotkb:Q3MJ34|ensembl:ENSP00000244573 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:h11_human(display_long)|uniprotkb:H1-1(gene name)|psi-mi:H1-1(display_short)|uniprotkb:H1F1(gene name synonym)|uniprotkb:HIST1H1A(gene name synonym)|uniprotkb:Histone H1a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_005316.1|ensembl:ENSG00000124610(gene)|ensembl:ENST00000244573(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q02539|reactome:R-HSA-140342|reactome:R-HSA-2559584 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:4u8P8jFM3onWx43+SxL320urjhk9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:P22492 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:A6NNZ2 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-6149104|ensembl:ENSP00000496713 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:tbb8b_human(display_long)|uniprotkb:TUBB8B(gene name)|psi-mi:TUBB8B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 ensembl:ENSG00000173213(gene)|ensembl:ENST00000308911(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-437239|reactome:R-HSA-5617833|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:ZnXdFJO1ou4waHhr2FQtj3RFb4g9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:P12036 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-2880271|uniprotkb:Q9UQ14|uniprotkb:Q9UJS7|uniprotkb:Q96HF8|uniprotkb:B4DYY4|ensembl:ENSP00000311997 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:nfh_human(display_long)|uniprotkb:NEFH(gene name)|psi-mi:NEFH(display_short)|uniprotkb:KIAA0845(gene name synonym)|uniprotkb:NFH(gene name synonym)|uniprotkb:200 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament triplet H protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_066554.2|ensembl:ENSG00000100285(gene)|ensembl:ENST00000310624(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005883"(neurofilament)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0061564"(axon development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR010790(Protein of unknown function DUF1388)|interpro:IPR018039|interpro:IPR033183|interpro:IPR039008|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:TXMrn6SWBHIYQY1loZfVvMo9PtU9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:P35326 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-1047940|uniprotkb:D3DV35|uniprotkb:B2R4T3|uniprotkb:Q5T529|ensembl:ENSP00000376423 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:spr2a_human(display_long)|uniprotkb:2-1(gene name synonym)|uniprotkb:SPRR2A(gene name)|psi-mi:SPRR2A(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_005979.1|ensembl:ENSG00000241794(gene)|ensembl:ENST00000392653(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|interpro:IPR029142|mint:P35326|reactome:R-HSA-6809371 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:36JcxOAjNryuf4Dhe4bnEVoO5lg9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:Q86YZ3 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-1047017|uniprotkb:Q5U1F4|ensembl:ENSP00000357791|uniprotkb:Q5DT20 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:horn_human(display_long)|uniprotkb:HRNR(gene name)|psi-mi:HRNR(display_short)|uniprotkb:S100A18(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_001009931.1|ensembl:ENSG00000197915(gene)|ensembl:ENST00000368801(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031424"(keratinization)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036457"(keratohyalin granule)|go:"GO:0043163"(cell envelope organization)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR033201|interpro:IPR034325|mint:Q86YZ3|reactome:R-HSA-6798695|ensembl:ENSP00000357791 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:j5ATFM7OQGbf5j+CZpJ3bJoadnc9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:Q99729 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:Q13885 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-711595|ensembl:ENSP00000369703|uniprotkb:Q6FGZ8|uniprotkb:Q8IWR2 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:tbb2a_human(display_long)|uniprotkb:TUBB2A(gene name)|psi-mi:TUBB2A(display_short)|uniprotkb:TUBB2(gene name synonym)|uniprotkb:Tubulin beta class IIa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-389957|reactome:R-HSA-983189|reactome:R-HSA-9668328|ensembl:ENSG00000137267(gene)|ensembl:ENST00000333628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q13885|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|refseq:NP_001060.1|refseq:NP_001297244.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:P15924 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-355041|uniprotkb:O75993|uniprotkb:Q14189|uniprotkb:Q9UHN4|uniprotkb:B2RTT2|uniprotkb:D7RX09|ensembl:ENSP00000369129 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:desp_human(display_long)|uniprotkb:DSP(gene name)|psi-mi:DSP(display_short)|uniprotkb:250/210 kDa paraneoplastic pemphigus antigen(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_001305963.1|refseq:NP_001008844.1|refseq:NP_004406.2|go:"GO:0014704"(intercalated disc)|go:"GO:0005916"(fascia adherens)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|ensembl:ENSG00000096696(gene)|ensembl:ENST00000379802(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:P15924|rcsb pdb:1LM5|rcsb pdb:1LM7|rcsb pdb:3R6N|rcsb pdb:5DZZ|reactome:R-HSA-351906|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9696264|reactome:R-HSA-9696273|dip:DIP-109N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:enapEqSoyTSLfPEQUAopkGpdxbo9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:P38159 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-743526|ensembl:ENSP00000359645|uniprotkb:Q5JQ67|uniprotkb:Q969R3|uniprotkb:D3DWH0|uniprotkb:E9PG86|uniprotkb:Q8N8Y7|uniprotkb:B4E3U4 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:rbmx_human(display_long)|uniprotkb:Glycoprotein p43(gene name synonym)|uniprotkb:RBMX(gene name)|psi-mi:RBMX(display_short)|uniprotkb:HNRPG(gene name synonym)|uniprotkb:RBMXP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 ensembl:ENSG00000147274(gene)|ensembl:ENST00000320676(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P38159|rcsb pdb:2MB0|rcsb pdb:2MKS|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_002130.2|refseq:NP_001158275.1|dip:DIP-34447N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:ocCkdy9PxjeVLUQf0tMVCEhFfO89606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:P06733 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:RmP7cr55H8ylcgBOEyivwljIE+09606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:Q3ZCM7 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-302558|ensembl:ENSP00000456206|intact:EBI-1390656|uniprotkb:Q5SQX9|uniprotkb:Q8WZ78 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:tbb8_human(display_long)|uniprotkb:TUBB8(gene name)|psi-mi:TUBB8(display_short)|uniprotkb:Tubulin beta 8 class VIII(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-9619483|ensembl:ENSG00000261456(gene)|ensembl:ENST00000568584(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001556"(oocyte maturation)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007056"(spindle assembly involved in female meiosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072687"(meiotic spindle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q3ZCM7|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-437239|reactome:R-HSA-5617833|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|refseq:NP_817124.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:bTJnhl0qEm2ACoHQ7IOcn5Rx7xM9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:P13929 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-4287222|uniprotkb:B4DUI6|uniprotkb:B4DUM6|uniprotkb:Q96AE2|uniprotkb:D3DTL2|uniprotkb:E7ENK8|ensembl:ENSP00000324105|ensembl:ENSP00000430055|ensembl:ENSP00000431087 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:enob_human(display_long)|uniprotkb:ENO3(gene name)|psi-mi:ENO3(display_short)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_001180432.1|refseq:NP_001967.3|refseq:NP_443739.3|refseq:XP_011522031.1|refseq:XP_016879835.1|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|rcsb pdb:2XSX|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENSG00000108515(gene)|ensembl:ENST00000323997(transcript)|ensembl:ENST00000518175(transcript)|ensembl:ENST00000519602(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:E25deDsQGp3y1HGuTqYwM1pUoD49606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:P67809 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:P07437 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:P62158 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:P09651 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-352662|uniprotkb:Q3MIB7|uniprotkb:Q6PJZ7|ensembl:ENSP00000341826|ensembl:ENSP00000503610|uniprotkb:A8K4Z8|intact:EBI-2556572 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:roa1_human(display_long)|uniprotkb:HNRNPA1(gene name)|psi-mi:HNRNPA1(display_short)|uniprotkb:HNRPA1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:Single-strand RNA-binding protein(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_002127.1|refseq:NP_112420.1|ensembl:ENSG00000135486(gene)|ensembl:ENST00000340913(transcript)|ensembl:ENST00000677210(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|rcsb pdb:2LYV|rcsb pdb:2UP1|rcsb pdb:4YOE|rcsb pdb:5MPG|rcsb pdb:5MPL|rcsb pdb:5ZGD|rcsb pdb:5ZGL|rcsb pdb:6BXX|rcsb pdb:6DCL|rcsb pdb:6J60|rcsb pdb:7BX7|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035198"(miRNA binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051170"(import into nucleus)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR034845|interpro:IPR035979|mint:P09651|rcsb pdb:1HA1|rcsb pdb:1L3K|rcsb pdb:1PGZ|rcsb pdb:1PO6|rcsb pdb:1U1K|rcsb pdb:1U1L|rcsb pdb:1U1M|rcsb pdb:1U1N|rcsb pdb:1U1O|rcsb pdb:1U1P|rcsb pdb:1U1Q|rcsb pdb:1U1R|rcsb pdb:1UP1|rcsb pdb:2H4M|refseq:XP_005268883.1|dip:DIP-29338N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:ECXjsLRVtNc/aOw90tEFxowHc6c9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:P35325 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-2556861|uniprotkb:Q5T528|ensembl:ENSP00000357744 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:spr2b_human(display_long)|uniprotkb:SPRR2B(gene name)|psi-mi:SPRR2B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_001017418.1|reactome:R-HSA-6809371|interpro:IPR029142|ensembl:ENSG00000196805(gene)|ensembl:ENST00000368755(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|refseq:XP_016857663.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:dcqpy2hWtNZOaZhTQkCsTi3EqW09606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:P55265 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-2462104|uniprotkb:B1AQR0|uniprotkb:O15223|uniprotkb:O43859|uniprotkb:O43860|uniprotkb:Q9BYM3|uniprotkb:Q9BYM4|uniprotkb:B1AQQ9|uniprotkb:D3DV76|ensembl:ENSP00000357459 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:dsrad_human(display_long)|uniprotkb:ADAR(gene name)|psi-mi:ADAR(display_short)|uniprotkb:ADAR1(gene name synonym)|uniprotkb:DSRAD(gene name synonym)|uniprotkb:G1P1(gene name synonym)|uniprotkb:IFI4(gene name synonym)|uniprotkb:136 kDa double-stranded RNA-binding protein(gene name synonym)|uniprotkb:K88DSRBP(gene name synonym)|uniprotkb:Interferon-inducible protein 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_001020278.1|refseq:NP_001102.2|refseq:NP_001180424.1|refseq:NP_056655.2|refseq:NP_056656.2|refseq:XP_006711174.1|refseq:XP_006711175.1|refseq:XP_006711176.1|dip:DIP-29310N|ensembl:ENSG00000160710(gene)|ensembl:ENST00000368474(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002566"(somatic diversification of immune receptors via somatic mutation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0008251"(tRNA-specific adenosine deaminase activity)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016553"(base conversion or substitution editing)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900369"(negative regulation of RNA interference)|interpro:IPR002466(Adenosine deaminase/editase)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371|interpro:IPR044456|interpro:IPR044457|mint:P55265|rcsb pdb:1QBJ|rcsb pdb:1QGP|rcsb pdb:1XMK|rcsb pdb:2ACJ|rcsb pdb:2GXB|rcsb pdb:2L54|rcsb pdb:2MDR|rcsb pdb:3F21|rcsb pdb:3F22|rcsb pdb:3F23|rcsb pdb:3IRQ|rcsb pdb:3IRR|rcsb pdb:5ZU1|rcsb pdb:5ZUO|rcsb pdb:5ZUP|rcsb pdb:7C0I|reactome:R-HSA-75102|reactome:R-HSA-77042|reactome:R-HSA-909733|go:"GO:0051607"(defense response to virus) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:rP/Yr/h8WLSFNdIuqWnYtZjZ9qI9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:O60506 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-1024357|uniprotkb:Q53H05|uniprotkb:Q5TCG2|uniprotkb:Q8IW78|uniprotkb:Q8N599|uniprotkb:Q96LC1|uniprotkb:Q96LC2|uniprotkb:Q9Y583|uniprotkb:Q5TCG3|uniprotkb:E1P501|uniprotkb:E1P502|ensembl:ENSP00000358635|ensembl:ENSP00000503783|ensembl:ENSP00000504706 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:hnrpq_human(display_long)|uniprotkb:Synaptotagmin-binding, cytoplasmic RNA-interacting protein(gene name synonym)|uniprotkb:Glycine- and tyrosine-rich RNA-binding protein(gene name synonym)|uniprotkb:NS1-associated protein 1(gene name synonym)|uniprotkb:SYNCRIP(gene name)|psi-mi:SYNCRIP(display_short)|uniprotkb:HNRPQ(gene name synonym)|uniprotkb:NSAP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_001153145.1|refseq:NP_001153146.1|refseq:NP_001153147.1|refseq:NP_001240700.1|refseq:NP_001153148.1|refseq:NP_001153149.1|refseq:NP_006363.4|ensembl:ENSG00000135316(gene)|ensembl:ENST00000369622(transcript)|ensembl:ENST00000676688(transcript)|ensembl:ENST00000678355(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034544|interpro:IPR034548|interpro:IPR035979|interpro:IPR041337|mint:O60506|rcsb pdb:2DGU|rcsb pdb:2MXT|rcsb pdb:2NBB|rcsb pdb:6KOR|refseq:XP_016865667.1|refseq:XP_005248694.1|dip:DIP-35540N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:2rDkXIp/wWzTOoVtN7Bd3uqZo689606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:P07910 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-357966|uniprotkb:P22628|uniprotkb:Q53EX2|uniprotkb:Q59FD3|uniprotkb:Q5FWE8|uniprotkb:Q86SF8|uniprotkb:Q86U45|uniprotkb:Q96HK7|uniprotkb:Q96HM4|uniprotkb:Q96IY5|uniprotkb:Q9BTS3|uniprotkb:D3DS19|uniprotkb:D3DS22|intact:EBI-28976506|ensembl:ENSP00000404848|ensembl:ENSP00000451291|ensembl:ENSP00000452276 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:hnrpc_human(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_001070910.1|refseq:NP_001070911.1|refseq:NP_004491.2|refseq:NP_112604.2|ensembl:ENSP00000404848|ensembl:ENST00000430246|ensembl:ENSP00000442816|ensembl:ENST00000553300|ensembl:ENSP00000450544|ensembl:ENSP00000451291|ensembl:ENST00000554969|ensembl:ENSP00000452276|ensembl:ENSP00000450725|ensembl:ENST00000555883|ensembl:ENSP00000450629|ensembl:ENST00000556628|ensembl:ENSP00000451652|ensembl:ENST00000556897|ensembl:ENSP00000451176|refseq:XP_011535010.1|refseq:XP_011535011.1|refseq:XP_011535012.1|refseq:XP_011535013.1|refseq:XP_011535014.1|refseq:XP_016876741.1|refseq:XP_016876742.1|dip:DIP-29854N|refseq:XP_006720188.1|ensembl:ENSG00000092199(gene)|ensembl:ENST00000420743(transcript)|ensembl:ENST00000554455(transcript)|ensembl:ENST00000557201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979|mint:P07910|rcsb pdb:1TXP|rcsb pdb:1WF2|rcsb pdb:2MXY|rcsb pdb:2MZ1|rcsb pdb:3LN4|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:Fj5tiH0wrNUjTnsURIg8dB8laMg9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:Q9BVA1 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-355665|uniprotkb:A8K068|ensembl:ENSP00000259818 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:tbb2b_human(display_long)|uniprotkb:TUBB2B(gene name)|psi-mi:TUBB2B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_821080.1|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BVA1|rcsb pdb:6E7C|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|ensembl:ENST00000259818(transcript)|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-5663220|ensembl:ENSG00000137285(gene) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:sluQMryNuOvp6xlV558+agiRwvE9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:Q08211 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-352022|intact:EBI-1058470|uniprotkb:Q5VY62|uniprotkb:Q6PD69|uniprotkb:Q99556|uniprotkb:B2RNV4|uniprotkb:Q05CI5|uniprotkb:Q12803|uniprotkb:Q32Q22|ensembl:ENSP00000356520 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:dhx9_human(display_long)|uniprotkb:DHX9(gene name)|psi-mi:DHX9(display_short)|uniprotkb:DDX9(gene name synonym)|uniprotkb:NDH2(gene name synonym)|uniprotkb:DExH-box helicase 9(gene name synonym)|uniprotkb:RNA helicase A(gene name synonym)|uniprotkb:LKP(gene name synonym)|uniprotkb:Nuclear DNA helicase II(gene name synonym)|uniprotkb:DEAH box protein 9(gene name synonym)|uniprotkb:Leukophysin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_001348.2|dip:DIP-31504N|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033679"(3'-5' DNA/RNA helicase activity)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045142"(triplex DNA binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0097165"(nuclear stress granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1905172"(RISC complex binding)|go:"GO:1905538"(polysome binding)|go:"GO:1905698"(positive regulation of polysome binding)|go:"GO:1990518"(single-stranded 3'-5' DNA helicase activity)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000765"(regulation of cytoplasmic translation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR044445|interpro:IPR044446|interpro:IPR044447|mint:Q08211|rcsb pdb:3LLM|rcsb pdb:3VYX|rcsb pdb:3VYY|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-72163|go:"GO:1904973"(positive regulation of viral translation)|ensembl:ENSG00000135829(gene)|ensembl:ENST00000367549(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006260"(DNA replication)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0016604"(nuclear body) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:b0VP2Frtvwa9WbYVMwB6TbV2uGU9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:Q12906 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-78756|uniprotkb:A8K6F2|uniprotkb:O43409|uniprotkb:Q6P1X1|uniprotkb:Q86XY7|uniprotkb:Q99544|uniprotkb:Q99545|uniprotkb:Q9BZH4|uniprotkb:Q9BZH5|uniprotkb:Q9NQ95|uniprotkb:Q9NQ96|uniprotkb:Q9NQ97|uniprotkb:Q9NQ98|uniprotkb:Q9NQ99|uniprotkb:Q9NQA0|uniprotkb:Q9NQA1|uniprotkb:Q9NQA2|uniprotkb:Q9NRN2|uniprotkb:Q9NRN3|uniprotkb:Q9NRN4|uniprotkb:Q9UMZ9|uniprotkb:Q9UN00|uniprotkb:Q9UN84|uniprotkb:Q9UNA2|ensembl:ENSP00000468156|intact:EBI-10970055|uniprotkb:G5E9M5 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:ilf3_human(display_long)|uniprotkb:ILF3(gene name)|psi-mi:ILF3(display_short)|uniprotkb:MPHOSPH4(gene name synonym)|uniprotkb:NF90(gene name synonym)|uniprotkb:Nuclear factor of activated T-cells 90 kDa(gene name synonym)|uniprotkb:Double-stranded RNA-binding protein 76(gene name synonym)|uniprotkb:Translational control protein 80(gene name synonym)|uniprotkb:Nuclear factor associated with dsRNA(gene name synonym)|uniprotkb:M-phase phosphoprotein 4(gene name synonym)|uniprotkb:DRBF(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 ensembl:ENSG00000129351(gene)|ensembl:ENST00000590261(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051607"(defense response to virus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR033099|interpro:IPR043519|mint:Q12906|rcsb pdb:2L33|rcsb pdb:3P1X|refseq:NP_001131145.1|refseq:NP_004507.2|refseq:NP_036350.2|refseq:NP_060090.2|refseq:NP_703194.1|refseq:XP_016882252.1|refseq:XP_011526286.2|dip:DIP-29853N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:iri+WBUtektANRSCpBO1XBCd9Wk9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:O43390 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-713419|uniprotkb:S4R3J4|uniprotkb:Q5TEH1|ensembl:ENSP00000304405|ensembl:ENSP00000363741|ensembl:ENSP00000489252|ensembl:ENSP00000489371|uniprotkb:Q9BV64|uniprotkb:Q2L7G6 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:hnrpr_human(display_long)|uniprotkb:HNRPR(gene name synonym)|uniprotkb:HNRNPR(gene name)|psi-mi:HNRNPR(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_001095868.1|refseq:XP_005245768.1|ensembl:ENSG00000125944(gene)|ensembl:ENSG00000282958(gene)|ensembl:ENST00000302271(transcript)|ensembl:ENST00000374612(transcript)|ensembl:ENST00000634263(transcript)|ensembl:ENST00000634766(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043679"(axon terminus)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034411|interpro:IPR035979|mint:O43390|rcsb pdb:2DK2|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR041337|refseq:NP_005817.1|refseq:XP_011538773.1|refseq:NP_001284549.1|refseq:XP_016855497.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:UiOaRbnMd1S2FthR4RWltyq6xT49606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:Q14103 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-299674|ensembl:ENSP00000313199|uniprotkb:P07029|uniprotkb:Q01858|uniprotkb:Q14100|uniprotkb:Q14101|uniprotkb:Q14102|uniprotkb:Q4W5A1|uniprotkb:A8K9J2|uniprotkb:Q9UCE8|uniprotkb:Q9UCE9 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:hnrpd_human(display_long)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 ensembl:ENSG00000138668(gene)|ensembl:ENST00000313899(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021549"(cerebellum development)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:1901355"(response to rapamycin)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904383"(response to sodium phosphate)|go:"GO:1904586"(cellular response to putrescine)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990828"(hepatocyte dedifferentiation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR035979|mint:Q14103|rcsb pdb:1HD0|rcsb pdb:1HD1|rcsb pdb:1IQT|rcsb pdb:1WTB|rcsb pdb:1X0F|rcsb pdb:2Z5N|rcsb pdb:5IM0|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|reactome:R-HSA-450408|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:NP_001003810.1|refseq:NP_002129.2|refseq:NP_112737.1|refseq:NP_112738.1|dip:DIP-31163N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:LrC0nOpN6jGn3WELs5NEOccNPnw9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:P22626 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:P61978 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-304185|intact:EBI-28971491|ensembl:ENSP00000317788|ensembl:ENSP00000353552|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q59F98|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62|uniprotkb:Q5T6W4|intact:EBI-3440248|uniprotkb:Q6IBN1 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:hnrpk_human(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 ensembl:ENSG00000165119(gene)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000351839(transcript)|ensembl:ENST00000360384(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0002102"(podosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61978|rcsb pdb:1J5K|rcsb pdb:1KHM|rcsb pdb:1ZZI|rcsb pdb:1ZZJ|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9610379|rcsb pdb:1ZZK|refseq:NP_002131.2|refseq:NP_112552.1|refseq:NP_112553.1|ensembl:ENSP00000317788|ensembl:ENSP00000353552|ensembl:ENST00000376263|ensembl:ENSP00000365439|ensembl:ENST00000376281|ensembl:ENSP00000365458|refseq:NP_001305115.1|refseq:NP_001305116.1|refseq:NP_001305117.1|refseq:XP_016870157.1|refseq:XP_005252017.1|refseq:XP_005252020.1|refseq:XP_005252022.1|dip:DIP-31805N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:Q9BYE4 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-6149100|ensembl:ENSP00000357737 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:spr2g_human(display_long)|uniprotkb:SPRR2G(gene name)|psi-mi:SPRR2G(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_001014313.1|refseq:XP_016857666.1|refseq:XP_016857667.1|ensembl:ENSG00000159516(gene)|ensembl:ENST00000368748(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|interpro:IPR029142|reactome:R-HSA-6809371 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:RtKMCbXL0+YibF+lE3+4hXzBmUQ9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:P09104 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-713154|ensembl:ENSP00000229277|ensembl:ENSP00000437402|ensembl:ENSP00000438873|uniprotkb:Q96J33|uniprotkb:B7Z2X9 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:enog_human(display_long)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Neural enolase(gene name synonym)|uniprotkb:Neuron-specific enolase(gene name synonym)|uniprotkb:Enolase 2(gene name synonym)|uniprotkb:ENO2(gene name)|psi-mi:ENO2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 rcsb pdb:2AKZ|rcsb pdb:3UCC|rcsb pdb:3UCD|rcsb pdb:3UJE|rcsb pdb:3UJF|rcsb pdb:3UJR|rcsb pdb:3UJS|rcsb pdb:4ZA0|rcsb pdb:4ZCW|rcsb pdb:5EU9|rcsb pdb:5IDZ|rcsb pdb:5TD9|rcsb pdb:5TIJ|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENST00000229277(transcript)|ensembl:ENST00000535366(transcript)|ensembl:ENST00000541477(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0043204"(perikaryon)|ensembl:ENSG00000111674(gene)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P09104|rcsb pdb:1TE6|rcsb pdb:2AKM|refseq:NP_001966.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:gNa8zN8RaWDRXjw/Z0sY6TAa/aA9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:P12277 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-357706|uniprotkb:Q2LE07|uniprotkb:A8K236|uniprotkb:B2R5R4|uniprotkb:Q6FG40|uniprotkb:Q9UC66|ensembl:ENSP00000299198 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:kcrb_human(display_long)|uniprotkb:CKB(gene name)|psi-mi:CKB(display_short)|uniprotkb:CKBB(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:Brain creatine kinase(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_001814.2|go:"GO:0005829"(cytosol)|ensembl:ENSG00000166165(gene)|ensembl:ENST00000348956(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12277|rcsb pdb:3B6R|rcsb pdb:3DRB|rcsb pdb:3DRE|rcsb pdb:6V9H|go:"GO:0021762"(substantia nigra development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|reactome:R-HSA-71288|reactome:R-HSA-9696264|dip:DIP-52968N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:WLRnU8sRUfJQoaPY0edGi9xiR+g9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:Q9BQE3 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:Q12905 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-357925|uniprotkb:A6NDB0|uniprotkb:Q5SR10|uniprotkb:Q5SR11|uniprotkb:Q7L7R3|uniprotkb:Q9BWD4|uniprotkb:Q9P1N0|uniprotkb:B2R8G7|ensembl:ENSP00000355011 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:ilf2_human(display_long)|uniprotkb:PRO3063(orf name)|uniprotkb:NF45(gene name synonym)|uniprotkb:ILF2(gene name)|psi-mi:ILF2(display_short)|uniprotkb:Nuclear factor of activated T-cells 45 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_004506.2|refseq:NP_001254738.1|ensembl:ENSG00000143621(gene)|ensembl:ENST00000361891(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR043519|mint:Q12905|reactome:R-HSA-6798695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:HwUDuY6Ev7csoTThxZCW8nJT88o9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:Q00839 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-351126|uniprotkb:O75507|uniprotkb:Q8N174|uniprotkb:Q96HY9|uniprotkb:Q9BQ09|ensembl:ENSP00000491215 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:hnrpu_human(display_long)|uniprotkb:HNRNPU(gene name)|psi-mi:HNRNPU(display_short)|uniprotkb:SAFA(gene name synonym)|uniprotkb:U21.1(gene name synonym)|uniprotkb:HNRPU(gene name synonym)|uniprotkb:p120(gene name synonym)|uniprotkb:pp120(gene name synonym)|uniprotkb:C1orf199(gene name synonym)|uniprotkb:GRIP120(gene name synonym)|uniprotkb:Nuclear p120 ribonucleoprotein(gene name synonym)|uniprotkb:Scaffold-attachment factor A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_004492.2|refseq:NP_114032.2|ensembl:ENSG00000153187(gene)|ensembl:ENST00000640218(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:1990498"(mitotic spindle microtubule)|go:"GO:0098577"(inactive sex chromosome)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR026745|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q00839|rcsb pdb:1ZRJ|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990280"(RNA localization to chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006396"(RNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008143"("poly(A) binding")|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0017130"("poly(C) RNA binding")|go:"GO:0030496"(midbody)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|refseq:XP_016856604.1|refseq:XP_016856605.1|refseq:XP_016856606.1|dip:DIP-684N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:n73PY0Vis+D5Iq0q77h5Ck2V4789606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:P22531 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-2556846|uniprotkb:Q5T9T4|uniprotkb:Q96RM2|ensembl:ENSP00000357739|ensembl:ENSP00000357740 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:spr2e_human(display_long)|uniprotkb:Small proline-rich protein II(gene name synonym)|uniprotkb:SPRR2E(gene name)|psi-mi:SPRR2E(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_001019380.2|ensembl:ENSG00000203785(gene)|ensembl:ENST00000368750(transcript)|ensembl:ENST00000368751(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0031424"(keratinization)|interpro:IPR029142|mint:P22531|reactome:R-HSA-6809371 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:Pwemojva9RHkLb7mVmctpxenpf49606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:P14923 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-702484|uniprotkb:Q15093|intact:EBI-988999|intact:EBI-744449|uniprotkb:Q9HCX9|uniprotkb:Q15151|uniprotkb:Q7L3S5|uniprotkb:Q86W21|uniprotkb:Q9BWC4|ensembl:ENSP00000311113|ensembl:ENSP00000377507|ensembl:ENSP00000377508 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:plak_human(display_long)|uniprotkb:JUP(gene name)|psi-mi:JUP(display_short)|uniprotkb:DP3(gene name synonym)|uniprotkb:CTNNG(gene name synonym)|uniprotkb:Desmoplakin-3(gene name synonym)|uniprotkb:Desmoplakin III(gene name synonym)|uniprotkb:Catenin gamma(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_002221.1|refseq:NP_068831.1|refseq:XP_011523055.1|refseq:XP_011523057.1|refseq:XP_011523058.1|refseq:XP_011523059.1|refseq:XP_011523060.1|refseq:XP_006721936.1|refseq:XP_006721937.1|refseq:XP_006721938.1|refseq:XP_006721941.1|refseq:XP_016880079.1|dip:DIP-36235N|ensembl:ENSG00000173801(gene)|ensembl:ENST00000310706(transcript)|ensembl:ENST00000393930(transcript)|ensembl:ENST00000393931(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002159"(desmosome assembly)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030057"(desmosome)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043588"(skin development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071603"(endothelial cell-cell adhesion)|go:"GO:0071665"(gamma-catenin-TCF7L2 complex)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR030461|mint:P14923|rcsb pdb:3IFQ|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:qOBUlbifyKUk1xF0Zr9jZPkZozc9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:P68371 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P21605 uniprotkb:P12273 intact:EBI-6149107|uniprotkb:Q76ZW2 intact:EBI-1049746|uniprotkb:A0A963|uniprotkb:A0A9C3|uniprotkb:A0A9F3|uniprotkb:A4D2I1|ensembl:ENSP00000291009 psi-mi:e3_vaccw(display_long)|uniprotkb:p25(gene name synonym)|uniprotkb:E3L(orf name)|uniprotkb:VACWR059(locus name) psi-mi:pip_human(display_long)|uniprotkb:Prolactin-induced protein(gene name synonym)|uniprotkb:Secretory actin-binding protein(gene name synonym)|uniprotkb:Gross cystic disease fluid protein 15(gene name synonym)|uniprotkb:gp17(gene name synonym)|uniprotkb:PIP(gene name)|psi-mi:PIP(display_short)|uniprotkb:GCDFP15(gene name synonym)|uniprotkb:GPIP4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156115|imex:IM-17331-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P21605|refseq:YP_232941.1|dip:DIP-2175N|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039579"(suppression by virus of host ISG15-protein conjugation)|go:"GO:0039580"(suppression by virus of host PKR signaling)|interpro:IPR009179(Interferon resistance/PKR inhibitor, vaccinia E3L type)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371 refseq:NP_002643.1|ensembl:ENSG00000159763(gene)|ensembl:ENST00000291009(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0003779"(actin binding)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006508"(proteolysis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019864"(IgG binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|interpro:IPR007990(Seminal vesicle autoantigen)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|mint:P12273|rcsb pdb:3ES6|reactome:R-HSA-5223345|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:DYwGRaSIXZHFPvGmcXzSaPkG9s010254 rogid:/OC16zeRzFp520uPPLHh+WekPPc9606 intact-crc:40B9D0272283C3DA|rigid:A3PwErZaHHccU5Pl1DsEn4SfiEY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P36313 uniprotkb:Q71UM5 intact:EBI-6149234|uniprotkb:O12396 intact:EBI-355126|uniprotkb:Q9BTJ1|ensembl:ENSP00000331019 psi-mi:icp34_hhv11(display_long)|uniprotkb:ICP34.5(gene name)|psi-mi:ICP34.5(display_short)|uniprotkb:Infected cell protein 34.5(gene name synonym)|uniprotkb:RL1(gene name synonym)|uniprotkb:"protein gamma(1)34.5"(gene name synonym) psi-mi:rs27l_human(display_long)|uniprotkb:RPS27L(gene name)|psi-mi:RPS27L(display_short)|uniprotkb:Small ribosomal subunit protein eS27-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156238|imex:IM-17331-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137073.1|refseq:YP_009137134.1|mint:P36313|interpro:IPR019523|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044196"(host cell nucleolus) refseq:NP_057004.1|ensembl:ENSG00000185088(gene)|ensembl:ENST00000330964(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0006412"(translation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008494"(translation activator activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:Q71UM5|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:HMk+q9hyMNjhP4+dRET76FW1Qac10299 rogid:OVIAlDF6dN3DxLZgQFrFl8r0Z0I9606 intact-crc:1394287F0BC7B6F2|rigid:lglm3nPsdx4C6x0P5Dj3MfhxbNU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P36313 uniprotkb:P62736 intact:EBI-6149234|uniprotkb:O12396 intact:EBI-698810|uniprotkb:P03996|uniprotkb:P04108|uniprotkb:Q6FI19|uniprotkb:B2R8A4|ensembl:ENSP00000224784 psi-mi:icp34_hhv11(display_long)|uniprotkb:ICP34.5(gene name)|psi-mi:ICP34.5(display_short)|uniprotkb:Infected cell protein 34.5(gene name synonym)|uniprotkb:RL1(gene name synonym)|uniprotkb:"protein gamma(1)34.5"(gene name synonym) psi-mi:acta_human(display_long)|uniprotkb:Alpha-actin-2(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 46 protein(gene name synonym)|uniprotkb:ACTA2(gene name)|psi-mi:ACTA2(display_short)|uniprotkb:ACTSA(gene name synonym)|uniprotkb:ACTVS(gene name synonym)|uniprotkb:GIG46(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156238|imex:IM-17331-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137073.1|refseq:YP_009137134.1|mint:P36313|interpro:IPR019523|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044196"(host cell nucleolus) refseq:NP_001135417.1|refseq:NP_001604.1|refseq:NP_001307784.1|ensembl:ENSG00000107796(gene)|ensembl:ENST00000224784(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014829"(vascular associated smooth muscle contraction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072144"(glomerular mesangial cell development)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P62736|reactome:R-HSA-445355|reactome:R-HSA-9013695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:HMk+q9hyMNjhP4+dRET76FW1Qac10299 rogid:mRZGUdL/jBuj6nVHtxoasZuA7yA9606 intact-crc:1394287F0BC7B6F2|rigid:lglm3nPsdx4C6x0P5Dj3MfhxbNU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P36313 uniprotkb:P63267 intact:EBI-6149234|uniprotkb:O12396 intact:EBI-297795|uniprotkb:P12718|uniprotkb:Q504R1|uniprotkb:Q6FI22|ensembl:ENSP00000295137|ensembl:ENSP00000386857|uniprotkb:B2R7E7|uniprotkb:D6W5H8|uniprotkb:B4E315|uniprotkb:E9PG30 psi-mi:icp34_hhv11(display_long)|uniprotkb:ICP34.5(gene name)|psi-mi:ICP34.5(display_short)|uniprotkb:Infected cell protein 34.5(gene name synonym)|uniprotkb:RL1(gene name synonym)|uniprotkb:"protein gamma(1)34.5"(gene name synonym) psi-mi:acth_human(display_long)|uniprotkb:ACTG2(gene name)|psi-mi:ACTG2(display_short)|uniprotkb:ACTA3(gene name synonym)|uniprotkb:ACTSG(gene name synonym)|uniprotkb:Smooth muscle gamma-actin(gene name synonym)|uniprotkb:Gamma-2-actin(gene name synonym)|uniprotkb:Alpha-actin-3(gene name synonym)|uniprotkb:ACTL3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156238|imex:IM-17331-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137073.1|refseq:YP_009137134.1|mint:P36313|interpro:IPR019523|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044196"(host cell nucleolus) go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0032982"(myosin filament)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:6JAT|reactome:R-HSA-445355|go:"GO:0010628"(positive regulation of gene expression)|ensembl:ENST00000345517(transcript)|ensembl:ENST00000409624(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|ensembl:ENSG00000163017(gene)|refseq:NP_001186822.1|refseq:NP_001606.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:HMk+q9hyMNjhP4+dRET76FW1Qac10299 rogid:tp0JsXhrGsRl5i4Wg2dyaPGUPxA9606 intact-crc:1394287F0BC7B6F2|rigid:lglm3nPsdx4C6x0P5Dj3MfhxbNU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P36313 uniprotkb:P07437 intact:EBI-6149234|uniprotkb:O12396 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:icp34_hhv11(display_long)|uniprotkb:ICP34.5(gene name)|psi-mi:ICP34.5(display_short)|uniprotkb:Infected cell protein 34.5(gene name synonym)|uniprotkb:RL1(gene name synonym)|uniprotkb:"protein gamma(1)34.5"(gene name synonym) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156238|imex:IM-17331-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137073.1|refseq:YP_009137134.1|mint:P36313|interpro:IPR019523|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044196"(host cell nucleolus) refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:HMk+q9hyMNjhP4+dRET76FW1Qac10299 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:1394287F0BC7B6F2|rigid:lglm3nPsdx4C6x0P5Dj3MfhxbNU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P36313 uniprotkb:Q9BQE3 intact:EBI-6149234|uniprotkb:O12396 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:icp34_hhv11(display_long)|uniprotkb:ICP34.5(gene name)|psi-mi:ICP34.5(display_short)|uniprotkb:Infected cell protein 34.5(gene name synonym)|uniprotkb:RL1(gene name synonym)|uniprotkb:"protein gamma(1)34.5"(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156238|imex:IM-17331-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137073.1|refseq:YP_009137134.1|mint:P36313|interpro:IPR019523|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044196"(host cell nucleolus) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:HMk+q9hyMNjhP4+dRET76FW1Qac10299 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:1394287F0BC7B6F2|rigid:lglm3nPsdx4C6x0P5Dj3MfhxbNU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P36313 uniprotkb:P12036 intact:EBI-6149234|uniprotkb:O12396 intact:EBI-2880271|uniprotkb:Q9UQ14|uniprotkb:Q9UJS7|uniprotkb:Q96HF8|uniprotkb:B4DYY4|ensembl:ENSP00000311997 psi-mi:icp34_hhv11(display_long)|uniprotkb:ICP34.5(gene name)|psi-mi:ICP34.5(display_short)|uniprotkb:Infected cell protein 34.5(gene name synonym)|uniprotkb:RL1(gene name synonym)|uniprotkb:"protein gamma(1)34.5"(gene name synonym) psi-mi:nfh_human(display_long)|uniprotkb:NEFH(gene name)|psi-mi:NEFH(display_short)|uniprotkb:KIAA0845(gene name synonym)|uniprotkb:NFH(gene name synonym)|uniprotkb:200 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament triplet H protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156238|imex:IM-17331-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137073.1|refseq:YP_009137134.1|mint:P36313|interpro:IPR019523|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044196"(host cell nucleolus) refseq:NP_066554.2|ensembl:ENSG00000100285(gene)|ensembl:ENST00000310624(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005883"(neurofilament)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0061564"(axon development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR010790(Protein of unknown function DUF1388)|interpro:IPR018039|interpro:IPR033183|interpro:IPR039008|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:HMk+q9hyMNjhP4+dRET76FW1Qac10299 rogid:TXMrn6SWBHIYQY1loZfVvMo9PtU9606 intact-crc:1394287F0BC7B6F2|rigid:lglm3nPsdx4C6x0P5Dj3MfhxbNU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P36313 uniprotkb:P62829 intact:EBI-6149234|uniprotkb:O12396 intact:EBI-353303|uniprotkb:P23131|uniprotkb:Q3SWV7|uniprotkb:P24048|uniprotkb:Q29246|uniprotkb:Q6P5S1|ensembl:ENSP00000377865|ensembl:ENSP00000420311 psi-mi:icp34_hhv11(display_long)|uniprotkb:ICP34.5(gene name)|psi-mi:ICP34.5(display_short)|uniprotkb:Infected cell protein 34.5(gene name synonym)|uniprotkb:RL1(gene name synonym)|uniprotkb:"protein gamma(1)34.5"(gene name synonym) psi-mi:rl23_human(display_long)|uniprotkb:RPL23(gene name)|psi-mi:RPL23(display_short)|uniprotkb:60S ribosomal protein L17(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156238|imex:IM-17331-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137073.1|refseq:YP_009137134.1|mint:P36313|interpro:IPR019523|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044196"(host cell nucleolus) rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|reactome:R-HSA-9010553|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|refseq:NP_000969.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000218(Ribosomal protein L14b/L23e)|interpro:IPR019972|interpro:IPR036853|mint:P62829|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|ensembl:ENSG00000125691(gene)|ensembl:ENST00000394332(transcript)|ensembl:ENST00000479035(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0005730"(nucleolus)|dip:DIP-33156N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:HMk+q9hyMNjhP4+dRET76FW1Qac10299 rogid:TiSVU2W4+lkwf12eb4+vG6IFlZA9606 intact-crc:1394287F0BC7B6F2|rigid:lglm3nPsdx4C6x0P5Dj3MfhxbNU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P36313 uniprotkb:P42677 intact:EBI-6149234|uniprotkb:O12396 intact:EBI-356336|ensembl:ENSP00000499044|uniprotkb:Q5T4L6 psi-mi:icp34_hhv11(display_long)|uniprotkb:ICP34.5(gene name)|psi-mi:ICP34.5(display_short)|uniprotkb:Infected cell protein 34.5(gene name synonym)|uniprotkb:RL1(gene name synonym)|uniprotkb:"protein gamma(1)34.5"(gene name synonym) psi-mi:rs27_human(display_long)|uniprotkb:RPS27(gene name)|psi-mi:RPS27(display_short)|uniprotkb:MPS1(gene name synonym)|uniprotkb:Metallopan-stimulin 1(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS27(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156238|imex:IM-17331-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137073.1|refseq:YP_009137134.1|mint:P36313|interpro:IPR019523|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044196"(host cell nucleolus) refseq:NP_001021.1|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|ensembl:ENSG00000177954(gene)|ensembl:ENST00000651669(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:P42677|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-141444|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-2500257|rcsb pdb:6OM7|reactome:R-HSA-5663220|reactome:R-HSA-6791226|reactome:R-HSA-68877|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-9648025|reactome:R-HSA-975956|reactome:R-HSA-975957|dip:DIP-44182N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:HMk+q9hyMNjhP4+dRET76FW1Qac10299 rogid:OA5IWAJDBpY5FFdVnun7Sq/jI7g9606 intact-crc:1394287F0BC7B6F2|rigid:lglm3nPsdx4C6x0P5Dj3MfhxbNU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P36313 uniprotkb:Q71U36 intact:EBI-6149234|uniprotkb:O12396 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:icp34_hhv11(display_long)|uniprotkb:ICP34.5(gene name)|psi-mi:ICP34.5(display_short)|uniprotkb:Infected cell protein 34.5(gene name synonym)|uniprotkb:RL1(gene name synonym)|uniprotkb:"protein gamma(1)34.5"(gene name synonym) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156238|imex:IM-17331-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137073.1|refseq:YP_009137134.1|mint:P36313|interpro:IPR019523|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044196"(host cell nucleolus) refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:HMk+q9hyMNjhP4+dRET76FW1Qac10299 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 intact-crc:1394287F0BC7B6F2|rigid:lglm3nPsdx4C6x0P5Dj3MfhxbNU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P36313 uniprotkb:P62805 intact:EBI-6149234|uniprotkb:O12396 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:icp34_hhv11(display_long)|uniprotkb:ICP34.5(gene name)|psi-mi:ICP34.5(display_short)|uniprotkb:Infected cell protein 34.5(gene name synonym)|uniprotkb:RL1(gene name synonym)|uniprotkb:"protein gamma(1)34.5"(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156238|imex:IM-17331-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137073.1|refseq:YP_009137134.1|mint:P36313|interpro:IPR019523|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044196"(host cell nucleolus) ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:HMk+q9hyMNjhP4+dRET76FW1Qac10299 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:1394287F0BC7B6F2|rigid:lglm3nPsdx4C6x0P5Dj3MfhxbNU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P36313 uniprotkb:P62269 intact:EBI-6149234|uniprotkb:O12396 intact:EBI-352451|ensembl:ENSP00000211372|ensembl:ENSP00000393241|ensembl:ENSP00000403175|ensembl:ENSP00000412583|ensembl:ENSP00000416110|uniprotkb:P25232|uniprotkb:Q6IPF8|uniprotkb:Q5SUJ3 psi-mi:icp34_hhv11(display_long)|uniprotkb:ICP34.5(gene name)|psi-mi:ICP34.5(display_short)|uniprotkb:Infected cell protein 34.5(gene name synonym)|uniprotkb:RL1(gene name synonym)|uniprotkb:"protein gamma(1)34.5"(gene name synonym) psi-mi:rs18_human(display_long)|uniprotkb:RPS18(gene name)|psi-mi:RPS18(display_short)|uniprotkb:D6S218E(gene name synonym)|uniprotkb:Ke-3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS13(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156238|imex:IM-17331-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137073.1|refseq:YP_009137134.1|mint:P36313|interpro:IPR019523|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044196"(host cell nucleolus) refseq:NP_072045.1|ensembl:ENSG00000096150(gene)|ensembl:ENSG00000223367(gene)|ensembl:ENSG00000226225(gene)|ensembl:ENSG00000231500(gene)|ensembl:ENSG00000235650(gene)|ensembl:ENST00000211372(transcript)|ensembl:ENST00000434122(transcript)|ensembl:ENST00000439602(transcript)|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENST00000454021(transcript)|ensembl:ENST00000457341(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001892(Ribosomal protein S13)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR018269|interpro:IPR027437|mint:P62269|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|dip:DIP-32892N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:HMk+q9hyMNjhP4+dRET76FW1Qac10299 rogid:yOHgKM/BuvgGdqp1OEVPeuiABg89606 intact-crc:1394287F0BC7B6F2|rigid:lglm3nPsdx4C6x0P5Dj3MfhxbNU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P36313 uniprotkb:P18621 intact:EBI-6149234|uniprotkb:O12396 intact:EBI-726937|uniprotkb:Q6NZ54|uniprotkb:Q7M4M5|uniprotkb:Q3KQW2|uniprotkb:B2R4H3|uniprotkb:B4E3C2|uniprotkb:B5ME31|uniprotkb:J3QL51|ensembl:ENSP00000462023|ensembl:ENSP00000462385|ensembl:ENSP00000463842|ensembl:ENSP00000480555|ensembl:ENSP00000482577 psi-mi:icp34_hhv11(display_long)|uniprotkb:ICP34.5(gene name)|psi-mi:ICP34.5(display_short)|uniprotkb:Infected cell protein 34.5(gene name synonym)|uniprotkb:RL1(gene name synonym)|uniprotkb:"protein gamma(1)34.5"(gene name synonym) psi-mi:rl17_human(display_long)|uniprotkb:60S ribosomal protein L23(gene name synonym)|uniprotkb:PD-1(gene name synonym)|uniprotkb:RPL17(gene name)|psi-mi:RPL17(display_short)|uniprotkb:Large ribosomal subunit protein uL22(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156238|imex:IM-17331-28 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137073.1|refseq:YP_009137134.1|mint:P36313|interpro:IPR019523|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039586"(modulation by virus of host PP1 activity)|go:"GO:0044196"(host cell nucleolus) refseq:NP_000976.1|refseq:NP_001030178.1|refseq:NP_001186269.1|refseq:NP_001186270.1|refseq:NP_001186271.1|refseq:NP_001186272.1|refseq:NP_001186273.1|refseq:NP_001186274.1|ensembl:ENSG00000265681(gene)|ensembl:ENST00000579248(transcript)|ensembl:ENST00000579408(transcript)|ensembl:ENST00000580261(transcript)|ensembl:ENST00000618613(transcript)|ensembl:ENST00000618619(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001063(Ribosomal protein L22/L17)|interpro:IPR005721(Ribosomal protein L22/L17, eukaryotic/archaeal)|interpro:IPR018260|interpro:IPR036394|mint:P18621|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:HMk+q9hyMNjhP4+dRET76FW1Qac10299 rogid:/i0W3WoeFakz+8R/YMYf2JQZytI9606 intact-crc:1394287F0BC7B6F2|rigid:lglm3nPsdx4C6x0P5Dj3MfhxbNU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23057 uniprotkb:P0C0S8 intact:EBI-6149327 intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538 psi-mi:v_pi2ht(display_long)|uniprotkb:P/V(gene name)|psi-mi:P/V(display_short) psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11214(pi2ht)|taxid:11214("Human parainfluenza 2 virus (strain Toshiba)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156319|imex:IM-17331-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR025909|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:nsKSwbsDwRYv38jjtEkoOuor83411214 rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606 intact-crc:DF5C9591A8F7815B|rigid:OhrrGJSBg/uTH54yBZZH6EtSoQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23057 uniprotkb:Q96KK5 intact:EBI-6149327 intact:EBI-6147668|ensembl:ENSP00000366679 psi-mi:v_pi2ht(display_long)|uniprotkb:P/V(gene name)|psi-mi:P/V(display_short) psi-mi:h2a1h_human(display_long)|uniprotkb:H2AC12(gene name)|psi-mi:H2AC12(display_short)|uniprotkb:H2A-clustered histone 12(gene name synonym)|uniprotkb:HIST1H2AH(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:Histone H2A/s(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11214(pi2ht)|taxid:11214("Human parainfluenza 2 virus (strain Toshiba)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156319|imex:IM-17331-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR025909|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_542163.1|dip:DIP-61699N|ensembl:ENSG00000274997(gene)|ensembl:ENST00000377459(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:nsKSwbsDwRYv38jjtEkoOuor83411214 rogid:Oa322n+evy8Cu0E9cWTEdYwQPKM9606 intact-crc:DF5C9591A8F7815B|rigid:OhrrGJSBg/uTH54yBZZH6EtSoQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23057 uniprotkb:P07437 intact:EBI-6149327 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:v_pi2ht(display_long)|uniprotkb:P/V(gene name)|psi-mi:P/V(display_short) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11214(pi2ht)|taxid:11214("Human parainfluenza 2 virus (strain Toshiba)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156319|imex:IM-17331-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR025909|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:nsKSwbsDwRYv38jjtEkoOuor83411214 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:DF5C9591A8F7815B|rigid:OhrrGJSBg/uTH54yBZZH6EtSoQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23057 uniprotkb:Q99878 intact:EBI-6149327 intact:EBI-6147676|uniprotkb:Q5JXQ5|uniprotkb:A2RUU6|ensembl:ENSP00000328484 psi-mi:v_pi2ht(display_long)|uniprotkb:P/V(gene name)|psi-mi:P/V(display_short) psi-mi:h2a1j_human(display_long)|uniprotkb:H2AC14(gene name)|psi-mi:H2AC14(display_short)|uniprotkb:H2AFE(gene name synonym)|uniprotkb:HIST1H2AJ(gene name synonym)|uniprotkb:Histone H2A/e(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11214(pi2ht)|taxid:11214("Human parainfluenza 2 virus (strain Toshiba)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156319|imex:IM-17331-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR025909|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_066544.1|ensembl:ENSG00000276368(gene)|ensembl:ENST00000333151(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:nsKSwbsDwRYv38jjtEkoOuor83411214 rogid:tS29VG3PpglHaYbu0w5z7pGvYyI9606 intact-crc:DF5C9591A8F7815B|rigid:OhrrGJSBg/uTH54yBZZH6EtSoQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23057 uniprotkb:P04908 intact:EBI-6149327 intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842 psi-mi:v_pi2ht(display_long)|uniprotkb:P/V(gene name)|psi-mi:P/V(display_short) psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11214(pi2ht)|taxid:11214("Human parainfluenza 2 virus (strain Toshiba)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156319|imex:IM-17331-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR025909|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:nsKSwbsDwRYv38jjtEkoOuor83411214 rogid:4Qno1mMYZB6FdNoojrzulWLVq849606 intact-crc:DF5C9591A8F7815B|rigid:OhrrGJSBg/uTH54yBZZH6EtSoQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23057 uniprotkb:Q93077 intact:EBI-6149327 intact:EBI-725259|uniprotkb:O00775|uniprotkb:O00776|uniprotkb:O00777|uniprotkb:O00778|uniprotkb:Q540R1|uniprotkb:B2R4F7|ensembl:ENSP00000321389|ensembl:ENSP00000367022|ensembl:ENSP00000473534 psi-mi:v_pi2ht(display_long)|uniprotkb:P/V(gene name)|psi-mi:P/V(display_short) psi-mi:h2a1c_human(display_long)|uniprotkb:H2AC6(gene name)|psi-mi:H2AC6(display_short)|uniprotkb:H2A-clustered histone 6(gene name synonym)|uniprotkb:H2AFL(gene name synonym)|uniprotkb:HIST1H2AC(gene name synonym)|uniprotkb:Histone H2A/l(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11214(pi2ht)|taxid:11214("Human parainfluenza 2 virus (strain Toshiba)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156319|imex:IM-17331-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR025909|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_003503.1|ensembl:ENSG00000180573(gene)|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENST00000314088(transcript)|ensembl:ENST00000377791(transcript)|ensembl:ENST00000602637(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|rcsb pdb:6C0W|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:7A08|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|interpro:IPR032458 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:nsKSwbsDwRYv38jjtEkoOuor83411214 rogid:m00IdooZksbNGKHSsaVvGFVpcko9606 intact-crc:DF5C9591A8F7815B|rigid:OhrrGJSBg/uTH54yBZZH6EtSoQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23057 uniprotkb:Q7L7L0 intact:EBI-6149327 intact:EBI-5325551|ensembl:ENSP00000355656|ensembl:ENSP00000493926|uniprotkb:B2R4S4 psi-mi:v_pi2ht(display_long)|uniprotkb:P/V(gene name)|psi-mi:P/V(display_short) psi-mi:h2a3_human(display_long)|uniprotkb:H2AW(gene name)|psi-mi:H2AW(display_short)|uniprotkb:HIST3H2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11214(pi2ht)|taxid:11214("Human parainfluenza 2 virus (strain Toshiba)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156319|imex:IM-17331-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR025909|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000181218(gene)|ensembl:ENSG00000284841(gene)|ensembl:ENST00000366695(transcript)|refseq:NP_254280.1|ensembl:ENST00000645741(transcript)|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-5689603|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q7L7L0|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000786"(nucleosome)|dip:DIP-48936N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:nsKSwbsDwRYv38jjtEkoOuor83411214 rogid:t0RdR1SmUtmwRjtCS3uTyLGqSUI9606 intact-crc:DF5C9591A8F7815B|rigid:OhrrGJSBg/uTH54yBZZH6EtSoQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23057 uniprotkb:Q16777 intact:EBI-6149327 intact:EBI-5325566|ensembl:ENSP00000332194|uniprotkb:Q6DRA7|uniprotkb:Q8IUE5 psi-mi:v_pi2ht(display_long)|uniprotkb:P/V(gene name)|psi-mi:P/V(display_short) psi-mi:h2a2c_human(display_long)|uniprotkb:H2AC20(gene name)|psi-mi:H2AC20(display_short)|uniprotkb:H2A-clustered histone 20(gene name synonym)|uniprotkb:H2AFQ(gene name synonym)|uniprotkb:HIST2H2AC(gene name synonym)|uniprotkb:Histone H2A-GL101(gene name synonym)|uniprotkb:Histone H2A/q(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11214(pi2ht)|taxid:11214("Human parainfluenza 2 virus (strain Toshiba)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156319|imex:IM-17331-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR025909|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-5689603|ensembl:ENSG00000184260(gene)|ensembl:ENST00000331380(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q16777|rcsb pdb:6Y5E|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|refseq:NP_003508.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:nsKSwbsDwRYv38jjtEkoOuor83411214 rogid:Wejrpp9wK3GvA4ahJDVyEH+cwlQ9606 intact-crc:DF5C9591A8F7815B|rigid:OhrrGJSBg/uTH54yBZZH6EtSoQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23057 uniprotkb:P20671 intact:EBI-6149327 intact:EBI-4407441|uniprotkb:A0PK91|uniprotkb:P57754|uniprotkb:Q6FGY6|ensembl:ENSP00000341094 psi-mi:v_pi2ht(display_long)|uniprotkb:P/V(gene name)|psi-mi:P/V(display_short) psi-mi:h2a1d_human(display_long)|uniprotkb:H2AC7(gene name)|psi-mi:H2AC7(display_short)|uniprotkb:H2AFG(gene name synonym)|uniprotkb:HIST1H2AD(gene name synonym)|uniprotkb:Histone H2A.3(gene name synonym)|uniprotkb:Histone H2A/g(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11214(pi2ht)|taxid:11214("Human parainfluenza 2 virus (strain Toshiba)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156319|imex:IM-17331-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR025909|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_066409.1|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000196866(gene)|ensembl:ENST00000341023(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:5GT3|rcsb pdb:6KBB|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:nsKSwbsDwRYv38jjtEkoOuor83411214 rogid:Geraq+dGw3pvAAhgzzXQnYxDOOw9606 intact-crc:DF5C9591A8F7815B|rigid:OhrrGJSBg/uTH54yBZZH6EtSoQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23057 uniprotkb:Q6FI13 intact:EBI-6149327 intact:EBI-353620|uniprotkb:P20670|uniprotkb:B2R5F0|ensembl:ENSP00000358155|ensembl:ENSP00000475814 psi-mi:v_pi2ht(display_long)|uniprotkb:P/V(gene name)|psi-mi:P/V(display_short) psi-mi:h2a2a_human(display_long)|uniprotkb:H2AC18(gene name)|psi-mi:H2AC18(display_short)|uniprotkb:H2AC19(gene name)|psi-mi:H2AC19(display_short)|uniprotkb:H2A-clustered histone 18(gene name synonym)|uniprotkb:H2A-clustered histone 19(gene name synonym)|uniprotkb:H2AFO(gene name synonym)|uniprotkb:HIST2H2AA(gene name synonym)|uniprotkb:HIST2H2AA3(gene name synonym)|uniprotkb:HIST2H2AA4(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/o(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11214(pi2ht)|taxid:11214("Human parainfluenza 2 virus (strain Toshiba)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156319|imex:IM-17331-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR025909|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_001035807.1|refseq:NP_003507.1|ensembl:ENSG00000203812(gene)|ensembl:ENSG00000272196(gene)|ensembl:ENST00000369159(transcript)|ensembl:ENST00000607355(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6Y5D|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|dip:DIP-33167N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:nsKSwbsDwRYv38jjtEkoOuor83411214 rogid:PMuIm2XMN5q4wk+wYJ94mmnCe4w9606 intact-crc:DF5C9591A8F7815B|rigid:OhrrGJSBg/uTH54yBZZH6EtSoQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23057 uniprotkb:Q9BTM1 intact:EBI-6149327 intact:EBI-4398590|uniprotkb:Q9NV63|ensembl:ENSP00000373730|ensembl:ENSP00000438553 psi-mi:v_pi2ht(display_long)|uniprotkb:P/V(gene name)|psi-mi:P/V(display_short) psi-mi:h2aj_human(display_long)|uniprotkb:H2AJ(gene name)|psi-mi:H2AJ(display_short)|uniprotkb:H2AFJ(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11214(pi2ht)|taxid:11214("Human parainfluenza 2 virus (strain Toshiba)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156319|imex:IM-17331-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR025909|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_808760.1|ensembl:ENSG00000246705(gene)|ensembl:ENST00000389078(transcript)|ensembl:ENST00000544848(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:4EDU|rcsb pdb:6K60|rcsb pdb:6KVD|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-8939236 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:nsKSwbsDwRYv38jjtEkoOuor83411214 rogid:g6br63FeM17yJRfQI3GnmoM0vbc9606 intact-crc:DF5C9591A8F7815B|rigid:OhrrGJSBg/uTH54yBZZH6EtSoQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23057 uniprotkb:Q16531 intact:EBI-6149327 intact:EBI-350322|uniprotkb:A6NG77|uniprotkb:O15176|uniprotkb:Q13289|ensembl:ENSP00000301764|ensembl:ENSP00000506223|ensembl:ENSP00000506685|uniprotkb:Q58F96|uniprotkb:B2R648|uniprotkb:B4DG00 psi-mi:v_pi2ht(display_long)|uniprotkb:P/V(gene name)|psi-mi:P/V(display_short) psi-mi:ddb1_human(display_long)|uniprotkb:DDB1(gene name)|psi-mi:DDB1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym)|uniprotkb:UV-damaged DNA-binding factor(gene name synonym)|uniprotkb:DDB p127 subunit(gene name synonym)|uniprotkb:DNA damage-binding protein a(gene name synonym)|uniprotkb:UV-damaged DNA-binding protein 1(gene name synonym)|uniprotkb:Xeroderma pigmentosum group E-complementing protein(gene name synonym)|uniprotkb:XPE-binding factor(gene name synonym)|uniprotkb:HBV X-associated protein 1(gene name synonym)|uniprotkb:XAP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11214(pi2ht)|taxid:11214("Human parainfluenza 2 virus (strain Toshiba)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156319|imex:IM-17331-30 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR025909|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_001914.3|rcsb pdb:3I89|rcsb pdb:3I8C|rcsb pdb:3I8E|rcsb pdb:4A08|rcsb pdb:4A09|rcsb pdb:4A0A|rcsb pdb:4A0B|rcsb pdb:4A0K|rcsb pdb:4A0L|rcsb pdb:4A11|rcsb pdb:4CI1|rcsb pdb:4CI2|rcsb pdb:4CI3|rcsb pdb:4E54|rcsb pdb:4E5Z|rcsb pdb:4TZ4|rcsb pdb:5FQD|rcsb pdb:5HXB|rcsb pdb:5JK7|rcsb pdb:5V3O|rcsb pdb:6BN7|ensembl:ENSG00000167986(gene)|ensembl:ENST00000301764(transcript)|ensembl:ENST00000680367(transcript)|ensembl:ENST00000681803(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030674"(protein-macromolecule adaptor activity)|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BOY|rcsb pdb:6DSZ|rcsb pdb:6FCV|rcsb pdb:6H0F|rcsb pdb:6H0G|rcsb pdb:6PAI|rcsb pdb:6Q0R|rcsb pdb:6Q0V|rcsb pdb:6Q0W|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6SJ7|rcsb pdb:6TD3|rcsb pdb:6UD7|rcsb pdb:6UE5|rcsb pdb:6UML|rcsb pdb:6XK9|rcsb pdb:7LPS|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0048511"(rhythmic process)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|interpro:IPR036322|mint:Q16531|rcsb pdb:2B5L|rcsb pdb:2B5M|rcsb pdb:2B5N|rcsb pdb:2HYE|rcsb pdb:3E0C|rcsb pdb:3EI1|rcsb pdb:3EI2|rcsb pdb:3EI3|rcsb pdb:3EI4|rcsb pdb:3I7H|rcsb pdb:3I7K|rcsb pdb:3I7L|rcsb pdb:3I7N|rcsb pdb:3I7O|rcsb pdb:3I7P|dip:DIP-430N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:nsKSwbsDwRYv38jjtEkoOuor83411214 rogid:qgMjZqvlsbGIGn2qM/pnLTtGyGM9606 intact-crc:DF5C9591A8F7815B|rigid:OhrrGJSBg/uTH54yBZZH6EtSoQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09992 uniprotkb:Q9BQE3 intact:EBI-6149284|uniprotkb:Q49K86 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:ncap_lycva(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym)|uniprotkb:Protein N(gene name synonym)|uniprotkb:Segment S(locus name) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11624(lcmv)|taxid:11624("Lymphocytic choriomeningitis virus (strain Armstrong)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156280|imex:IM-17331-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000229(Arenavirus nucleocapsid protein)|refseq:NP_694852.1|interpro:IPR035083|interpro:IPR035084|rcsb pdb:4O6H|rcsb pdb:4O6I|interpro:IPR038115|go:"GO:0003723"(RNA binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0039696"(RNA-templated viral transcription)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0046872"(metal ion binding) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:hC9eHRWP4BboODOSihXfygjHhjU11624 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:703ED0AFD09B0F25|rigid:JXj5pMGyJbbQJN4vMxRD5r4Xo5s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09992 uniprotkb:P48643 intact:EBI-6149284|uniprotkb:Q49K86 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:ncap_lycva(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym)|uniprotkb:Protein N(gene name synonym)|uniprotkb:Segment S(locus name) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11624(lcmv)|taxid:11624("Lymphocytic choriomeningitis virus (strain Armstrong)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156280|imex:IM-17331-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000229(Arenavirus nucleocapsid protein)|refseq:NP_694852.1|interpro:IPR035083|interpro:IPR035084|rcsb pdb:4O6H|rcsb pdb:4O6I|interpro:IPR038115|go:"GO:0003723"(RNA binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0039696"(RNA-templated viral transcription)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0046872"(metal ion binding) refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:hC9eHRWP4BboODOSihXfygjHhjU11624 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:703ED0AFD09B0F25|rigid:JXj5pMGyJbbQJN4vMxRD5r4Xo5s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09992 uniprotkb:Q8NF91 intact:EBI-6149284|uniprotkb:Q49K86 intact:EBI-928867|uniprotkb:E7EQI5|uniprotkb:O94890|uniprotkb:Q5JV19|uniprotkb:Q5JV22|uniprotkb:Q8N9P7|uniprotkb:Q8TCP1|uniprotkb:Q8WWW6|uniprotkb:Q8WWW7|uniprotkb:Q8WXF6|uniprotkb:Q96N17|uniprotkb:Q9C0A7|uniprotkb:Q9H525|uniprotkb:Q9H526|uniprotkb:Q9NS36|uniprotkb:Q9NU50|uniprotkb:Q9UJ06|uniprotkb:Q9UJ07|uniprotkb:Q9ULF8|uniprotkb:B3W695|uniprotkb:H0Y4C0|uniprotkb:Q3ZCV0|ensembl:ENSP00000356224 psi-mi:ncap_lycva(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym)|uniprotkb:Protein N(gene name synonym)|uniprotkb:Segment S(locus name) psi-mi:syne1_human(display_long)|uniprotkb:SYNE1(gene name)|psi-mi:SYNE1(display_short)|uniprotkb:KIAA0796(gene name synonym)|uniprotkb:KIAA1262(gene name synonym)|uniprotkb:KIAA1756(gene name synonym)|uniprotkb:MYNE1(gene name synonym)|uniprotkb:Nuclear envelope spectrin repeat protein 1(gene name synonym)|uniprotkb:Synaptic nuclear envelope protein 1(gene name synonym)|uniprotkb:Myocyte nuclear envelope protein 1(gene name synonym)|uniprotkb:C6orf98(gene name synonym)|uniprotkb:Enaptin(gene name synonym)|uniprotkb:KASH domain-containing protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11624(lcmv)|taxid:11624("Lymphocytic choriomeningitis virus (strain Armstrong)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156280|imex:IM-17331-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000229(Arenavirus nucleocapsid protein)|refseq:NP_694852.1|interpro:IPR035083|interpro:IPR035084|rcsb pdb:4O6H|rcsb pdb:4O6I|interpro:IPR038115|go:"GO:0003723"(RNA binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0039696"(RNA-templated viral transcription)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0046872"(metal ion binding) refseq:NP_001334631.1|refseq:NP_149062.1|refseq:NP_892006.3|ensembl:ENSG00000131018(gene)|ensembl:ENST00000367255(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006997"(nucleus organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030017"(sarcomere)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051015"(actin filament binding)|go:"GO:0090292"(nuclear matrix anchoring at nuclear membrane)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR012315(Klarsicht/ANC-1/syne-1 homology)|interpro:IPR018159|interpro:IPR036872|mint:Q8NF91|rcsb pdb:4DXR|rcsb pdb:6R15|rcsb pdb:6XF2|reactome:R-HSA-1221632 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:hC9eHRWP4BboODOSihXfygjHhjU11624 rogid:6nWMBf60nycHwNcMMQJL5JqanEc9606 intact-crc:703ED0AFD09B0F25|rigid:JXj5pMGyJbbQJN4vMxRD5r4Xo5s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09992 uniprotkb:Q71U36 intact:EBI-6149284|uniprotkb:Q49K86 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:ncap_lycva(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym)|uniprotkb:Protein N(gene name synonym)|uniprotkb:Segment S(locus name) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11624(lcmv)|taxid:11624("Lymphocytic choriomeningitis virus (strain Armstrong)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156280|imex:IM-17331-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000229(Arenavirus nucleocapsid protein)|refseq:NP_694852.1|interpro:IPR035083|interpro:IPR035084|rcsb pdb:4O6H|rcsb pdb:4O6I|interpro:IPR038115|go:"GO:0003723"(RNA binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0039696"(RNA-templated viral transcription)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0046872"(metal ion binding) refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:hC9eHRWP4BboODOSihXfygjHhjU11624 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 intact-crc:703ED0AFD09B0F25|rigid:JXj5pMGyJbbQJN4vMxRD5r4Xo5s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09992 uniprotkb:Q99832 intact:EBI-6149284|uniprotkb:Q49K86 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:ncap_lycva(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym)|uniprotkb:Protein N(gene name synonym)|uniprotkb:Segment S(locus name) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11624(lcmv)|taxid:11624("Lymphocytic choriomeningitis virus (strain Armstrong)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156280|imex:IM-17331-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000229(Arenavirus nucleocapsid protein)|refseq:NP_694852.1|interpro:IPR035083|interpro:IPR035084|rcsb pdb:4O6H|rcsb pdb:4O6I|interpro:IPR038115|go:"GO:0003723"(RNA binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0039696"(RNA-templated viral transcription)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0046872"(metal ion binding) dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:hC9eHRWP4BboODOSihXfygjHhjU11624 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 intact-crc:703ED0AFD09B0F25|rigid:JXj5pMGyJbbQJN4vMxRD5r4Xo5s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09992 uniprotkb:P50990 intact:EBI-6149284|uniprotkb:Q49K86 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:ncap_lycva(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym)|uniprotkb:Protein N(gene name synonym)|uniprotkb:Segment S(locus name) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11624(lcmv)|taxid:11624("Lymphocytic choriomeningitis virus (strain Armstrong)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156280|imex:IM-17331-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000229(Arenavirus nucleocapsid protein)|refseq:NP_694852.1|interpro:IPR035083|interpro:IPR035084|rcsb pdb:4O6H|rcsb pdb:4O6I|interpro:IPR038115|go:"GO:0003723"(RNA binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0039696"(RNA-templated viral transcription)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0046872"(metal ion binding) refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:hC9eHRWP4BboODOSihXfygjHhjU11624 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 intact-crc:703ED0AFD09B0F25|rigid:JXj5pMGyJbbQJN4vMxRD5r4Xo5s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09992 uniprotkb:P17987 intact:EBI-6149284|uniprotkb:Q49K86 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:ncap_lycva(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym)|uniprotkb:Protein N(gene name synonym)|uniprotkb:Segment S(locus name) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11624(lcmv)|taxid:11624("Lymphocytic choriomeningitis virus (strain Armstrong)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156280|imex:IM-17331-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000229(Arenavirus nucleocapsid protein)|refseq:NP_694852.1|interpro:IPR035083|interpro:IPR035084|rcsb pdb:4O6H|rcsb pdb:4O6I|interpro:IPR038115|go:"GO:0003723"(RNA binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0039696"(RNA-templated viral transcription)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0046872"(metal ion binding) refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:hC9eHRWP4BboODOSihXfygjHhjU11624 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 intact-crc:703ED0AFD09B0F25|rigid:JXj5pMGyJbbQJN4vMxRD5r4Xo5s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09992 uniprotkb:P40227 intact:EBI-6149284|uniprotkb:Q49K86 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:ncap_lycva(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym)|uniprotkb:Protein N(gene name synonym)|uniprotkb:Segment S(locus name) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11624(lcmv)|taxid:11624("Lymphocytic choriomeningitis virus (strain Armstrong)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156280|imex:IM-17331-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000229(Arenavirus nucleocapsid protein)|refseq:NP_694852.1|interpro:IPR035083|interpro:IPR035084|rcsb pdb:4O6H|rcsb pdb:4O6I|interpro:IPR038115|go:"GO:0003723"(RNA binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0039696"(RNA-templated viral transcription)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0046872"(metal ion binding) refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:hC9eHRWP4BboODOSihXfygjHhjU11624 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 intact-crc:703ED0AFD09B0F25|rigid:JXj5pMGyJbbQJN4vMxRD5r4Xo5s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09992 uniprotkb:P49368 intact:EBI-6149284|uniprotkb:Q49K86 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:ncap_lycva(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym)|uniprotkb:Protein N(gene name synonym)|uniprotkb:Segment S(locus name) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11624(lcmv)|taxid:11624("Lymphocytic choriomeningitis virus (strain Armstrong)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156280|imex:IM-17331-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000229(Arenavirus nucleocapsid protein)|refseq:NP_694852.1|interpro:IPR035083|interpro:IPR035084|rcsb pdb:4O6H|rcsb pdb:4O6I|interpro:IPR038115|go:"GO:0003723"(RNA binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0039696"(RNA-templated viral transcription)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0046872"(metal ion binding) refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:hC9eHRWP4BboODOSihXfygjHhjU11624 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:703ED0AFD09B0F25|rigid:JXj5pMGyJbbQJN4vMxRD5r4Xo5s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09992 uniprotkb:P50991 intact:EBI-6149284|uniprotkb:Q49K86 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:ncap_lycva(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym)|uniprotkb:Protein N(gene name synonym)|uniprotkb:Segment S(locus name) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11624(lcmv)|taxid:11624("Lymphocytic choriomeningitis virus (strain Armstrong)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156280|imex:IM-17331-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000229(Arenavirus nucleocapsid protein)|refseq:NP_694852.1|interpro:IPR035083|interpro:IPR035084|rcsb pdb:4O6H|rcsb pdb:4O6I|interpro:IPR038115|go:"GO:0003723"(RNA binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0039696"(RNA-templated viral transcription)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0046872"(metal ion binding) refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:hC9eHRWP4BboODOSihXfygjHhjU11624 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 intact-crc:703ED0AFD09B0F25|rigid:JXj5pMGyJbbQJN4vMxRD5r4Xo5s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P09992 uniprotkb:P78371 intact:EBI-6149284|uniprotkb:Q49K86 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:ncap_lycva(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:Nucleocapsid protein(gene name synonym)|uniprotkb:Protein N(gene name synonym)|uniprotkb:Segment S(locus name) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11624(lcmv)|taxid:11624("Lymphocytic choriomeningitis virus (strain Armstrong)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156280|imex:IM-17331-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000229(Arenavirus nucleocapsid protein)|refseq:NP_694852.1|interpro:IPR035083|interpro:IPR035084|rcsb pdb:4O6H|rcsb pdb:4O6I|interpro:IPR038115|go:"GO:0003723"(RNA binding)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019029"(helical viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039689"(negative stranded viral RNA replication)|go:"GO:0039696"(RNA-templated viral transcription)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0046872"(metal ion binding) refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:hC9eHRWP4BboODOSihXfygjHhjU11624 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 intact-crc:703ED0AFD09B0F25|rigid:JXj5pMGyJbbQJN4vMxRD5r4Xo5s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:P42677 intact:EBI-6149376 intact:EBI-356336|ensembl:ENSP00000499044|uniprotkb:Q5T4L6 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:rs27_human(display_long)|uniprotkb:RPS27(gene name)|psi-mi:RPS27(display_short)|uniprotkb:MPS1(gene name synonym)|uniprotkb:Metallopan-stimulin 1(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS27(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_001021.1|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|ensembl:ENSG00000177954(gene)|ensembl:ENST00000651669(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:P42677|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-141444|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-2500257|rcsb pdb:6OM7|reactome:R-HSA-5663220|reactome:R-HSA-6791226|reactome:R-HSA-68877|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-9648025|reactome:R-HSA-975956|reactome:R-HSA-975957|dip:DIP-44182N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:OA5IWAJDBpY5FFdVnun7Sq/jI7g9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:Q06830 intact:EBI-6149376 intact:EBI-353193|ensembl:ENSP00000262746|ensembl:ENSP00000361152|ensembl:ENSP00000389047|ensembl:ENSP00000407034|ensembl:ENSP00000503140|uniprotkb:P35703|uniprotkb:Q2V576|uniprotkb:Q5T154|uniprotkb:Q5T155|uniprotkb:B5BU26|uniprotkb:D3DPZ8 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:prdx1_human(display_long)|uniprotkb:PRDX1(gene name)|psi-mi:PRDX1(display_short)|uniprotkb:PAGA(gene name synonym)|uniprotkb:PAGB(gene name synonym)|uniprotkb:TDPX2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Proliferation-associated gene protein(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor A(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000117450(gene)|ensembl:ENST00000262746(transcript)|ensembl:ENST00000319248(transcript)|ensembl:ENST00000424390(transcript)|ensembl:ENST00000447184(transcript)|ensembl:ENST00000676549(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003723"(RNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042470"(melanosome)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q06830|rcsb pdb:2RII|rcsb pdb:3HY2|rcsb pdb:4XCS|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803|refseq:NP_001189360.1|refseq:NP_002565.1|refseq:NP_859047.1|refseq:NP_859048.1|dip:DIP-33152N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:ZM5ZXF900izH81QVqgd2+opwMrs9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:P62854 intact:EBI-6149376 intact:EBI-353438|uniprotkb:P02383|uniprotkb:Q3MHD8|uniprotkb:P70394|uniprotkb:Q06722|uniprotkb:Q6IRY4|ensembl:ENSP00000348849|ensembl:ENSP00000450339|ensembl:ENSP00000496643 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:rs26_human(display_long)|uniprotkb:RPS26(gene name)|psi-mi:RPS26(display_short)|uniprotkb:Small ribosomal subunit protein eS26(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_001020.2|refseq:XP_005276741.1|rcsb pdb:6OLG|rcsb pdb:6OLF|ensembl:ENST00000356464(transcript)|ensembl:ENST00000552361(transcript)|ensembl:ENST00000646449(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000892(Ribosomal protein S26e)|interpro:IPR038551|mint:P62854|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6G5H|ensembl:ENSG00000197728(gene)|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-156827 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:bo2ruYMNjjLCMo/kwAWzmlJrrjU9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:Q9BVA1 intact:EBI-6149376 intact:EBI-355665|uniprotkb:A8K068|ensembl:ENSP00000259818 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:tbb2b_human(display_long)|uniprotkb:TUBB2B(gene name)|psi-mi:TUBB2B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_821080.1|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BVA1|rcsb pdb:6E7C|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|ensembl:ENST00000259818(transcript)|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-5663220|ensembl:ENSG00000137285(gene) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:sluQMryNuOvp6xlV558+agiRwvE9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:Q76NI1 intact:EBI-6149376 intact:EBI-3893082|uniprotkb:B0QZC5|uniprotkb:Q5T233|uniprotkb:Q6ZNH8|uniprotkb:Q8TEE5|uniprotkb:Q96LV7|uniprotkb:Q9C095|ensembl:ENSP00000304437 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:kndc1_human(display_long)|uniprotkb:Ras-GEF domain-containing family member 2(gene name synonym)|uniprotkb:hucep-9(orf name)|uniprotkb:KNDC1(gene name)|psi-mi:KNDC1(display_short)|uniprotkb:C10orf23(gene name synonym)|uniprotkb:KIAA1768(gene name synonym)|uniprotkb:RASGEF2(gene name synonym)|uniprotkb:VKIND(gene name synonym)|uniprotkb:Cerebral protein 9(gene name synonym)|uniprotkb:Protein very KIND(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_689856.6|ensembl:ENSG00000171798(gene)|ensembl:ENST00000304613(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050773"(regulation of dendrite development)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011019(KIND)|interpro:IPR023578|interpro:IPR029899|interpro:IPR036964|mint:Q76NI1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:ODxYPSXNJ8Q6RBPE4ceSToaLVOQ9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:Q9Y2S7 intact:EBI-6149376 intact:EBI-713000|ensembl:ENSP00000475924|uniprotkb:Q96JE4|uniprotkb:B2R846 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:pdip2_human(display_long)|uniprotkb:38 kDa DNA polymerase delta interaction protein(gene name synonym)|uniprotkb:POLDIP2(gene name)|psi-mi:POLDIP2(display_short)|uniprotkb:PDIP38(gene name synonym)|uniprotkb:POLD4(gene name synonym)|uniprotkb:HSPC017(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000004142(gene)|ensembl:ENST00000540200(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1903490"(positive regulation of mitotic cytokinesis)|go:"GO:1904531"(positive regulation of actin filament binding)|go:"GO:1990874"(vascular associated smooth muscle cell proliferation)|go:"GO:2001108"(positive regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR007474(ApaG)|interpro:IPR011722(Hemimethylated DNA-binding region)|interpro:IPR036623|interpro:IPR036767|mint:Q9Y2S7|rcsb pdb:6Z9C|refseq:NP_056399.1|refseq:NP_001277074.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:eZmek2xqphKowjP6zwsH6ydfz3g9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:P04350 intact:EBI-6149376 intact:EBI-355007|uniprotkb:B3KQP4|uniprotkb:Q969E5|ensembl:ENSP00000264071 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:tbb4a_human(display_long)|uniprotkb:TUBB4A(gene name)|psi-mi:TUBB4A(display_short)|uniprotkb:TUBB4(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:Tubulin 5 beta(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_006078.2|ensembl:ENSG00000104833(gene)|ensembl:ENST00000264071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0033269"(internode region of axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P04350|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001276052.1|refseq:NP_001276056.1|refseq:NP_001276058.1|refseq:NP_001276059.1|refseq:NP_001276060.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:mMveBNZkQs2x0dyHm/ghVWBe4/49606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:Q9BQE3 intact:EBI-6149376 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:P07437 intact:EBI-6149376 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:Q00325 intact:EBI-6149376 intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325 - - crc64:78714C85931B22D5 figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:P36542 intact:EBI-6149376 intact:EBI-711768|uniprotkb:Q5VYP3|uniprotkb:Q96AS8|uniprotkb:A8KA31|intact:EBI-3962282|uniprotkb:Q6I9V2|ensembl:ENSP00000349142 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:atpg_human(display_long)|uniprotkb:ATP5F1C(gene name)|psi-mi:ATP5F1C(display_short)|uniprotkb:ATP synthase F1 subunit gamma(gene name synonym)|uniprotkb:ATP5C(gene name synonym)|uniprotkb:ATP5C1(gene name synonym)|uniprotkb:ATP5CL1(gene name synonym)|uniprotkb:F-ATPase gamma subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_001001973.1|refseq:NP_005165.1|ensembl:ENSG00000165629(gene)|ensembl:ENST00000356708(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968|mint:P36542|reactome:R-HSA-163210|reactome:R-HSA-8949613 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:k3Nfa1hSoREyiKzFbmaZqxLhiLY9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:P30048 intact:EBI-6149376 intact:EBI-748336|intact:EBI-10975142|uniprotkb:P35690|uniprotkb:Q0D2H1|uniprotkb:Q13776|uniprotkb:Q5T5V2|uniprotkb:Q96HK4|uniprotkb:B2R7Z0|uniprotkb:D3DRC9|uniprotkb:E9PH29|ensembl:ENSP00000298510 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:prdx3_human(display_long)|uniprotkb:Peroxiredoxin-3(gene name synonym)|uniprotkb:Peroxiredoxin III(gene name synonym)|uniprotkb:Antioxidant protein 1(gene name synonym)|uniprotkb:Protein MER5 homolog(gene name synonym)|uniprotkb:HBC189(gene name synonym)|uniprotkb:PRDX3(gene name)|psi-mi:PRDX3(display_short)|uniprotkb:AOP1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_001289201.1|refseq:NP_006784.1|ensembl:ENSG00000165672(gene)|ensembl:ENST00000298510(transcript)|go:"GO:0001893"(maternal placenta development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008785"(alkyl hydroperoxide reductase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:P30048|rcsb pdb:5JCG|rcsb pdb:5UCX|reactome:R-HSA-3299685|go:"GO:0005769"(early endosome)|dip:DIP-33600N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:+J/zV8u0jGCSzTGXafxgecTv/149606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:P11021 intact:EBI-6149376 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:P12236 intact:EBI-6149376 intact:EBI-356254|ensembl:ENSP00000370808|uniprotkb:Q96C49 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000169100(gene)|ensembl:ENST00000381401(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|refseq:NP_001627.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:Q96EY1 intact:EBI-6149376 intact:EBI-356767|uniprotkb:O75472|uniprotkb:Q8WUJ6|uniprotkb:Q8WXJ3|uniprotkb:Q96D76|uniprotkb:Q96IV1|uniprotkb:Q9NYH8|uniprotkb:B2RAJ5|uniprotkb:B4DI33|uniprotkb:E7ES32|ensembl:ENSP00000262375|ensembl:ENSP00000477570 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:dnja3_human(display_long)|uniprotkb:DNAJA3(gene name)|psi-mi:DNAJA3(display_short)|uniprotkb:TID1(gene name synonym)|uniprotkb:HCA57(gene name synonym)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 57(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_001273445.1|refseq:NP_001128582.1|refseq:NP_005138.3|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0106137"(IkappaB kinase complex binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|mint:Q96EY1|rcsb pdb:2CTT|rcsb pdb:2DN9|rcsb pdb:6IWS|ensembl:ENSG00000103423(gene)|ensembl:ENSG00000276726(gene)|ensembl:ENST00000262375(transcript)|ensembl:ENST00000612103(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005133"(interferon-gamma receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006457"(protein folding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007569"(cell aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|dip:DIP-33870N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:WnRYdQ9E3yGbSlq1SSGTX9k+3uA9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:Q13263 intact:EBI-6149376 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:P07910 intact:EBI-6149376 intact:EBI-357966|uniprotkb:P22628|uniprotkb:Q53EX2|uniprotkb:Q59FD3|uniprotkb:Q5FWE8|uniprotkb:Q86SF8|uniprotkb:Q86U45|uniprotkb:Q96HK7|uniprotkb:Q96HM4|uniprotkb:Q96IY5|uniprotkb:Q9BTS3|uniprotkb:D3DS19|uniprotkb:D3DS22|intact:EBI-28976506|ensembl:ENSP00000404848|ensembl:ENSP00000451291|ensembl:ENSP00000452276 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:hnrpc_human(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_001070910.1|refseq:NP_001070911.1|refseq:NP_004491.2|refseq:NP_112604.2|ensembl:ENSP00000404848|ensembl:ENST00000430246|ensembl:ENSP00000442816|ensembl:ENST00000553300|ensembl:ENSP00000450544|ensembl:ENSP00000451291|ensembl:ENST00000554969|ensembl:ENSP00000452276|ensembl:ENSP00000450725|ensembl:ENST00000555883|ensembl:ENSP00000450629|ensembl:ENST00000556628|ensembl:ENSP00000451652|ensembl:ENST00000556897|ensembl:ENSP00000451176|refseq:XP_011535010.1|refseq:XP_011535011.1|refseq:XP_011535012.1|refseq:XP_011535013.1|refseq:XP_011535014.1|refseq:XP_016876741.1|refseq:XP_016876742.1|dip:DIP-29854N|refseq:XP_006720188.1|ensembl:ENSG00000092199(gene)|ensembl:ENST00000420743(transcript)|ensembl:ENST00000554455(transcript)|ensembl:ENST00000557201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979|mint:P07910|rcsb pdb:1TXP|rcsb pdb:1WF2|rcsb pdb:2MXY|rcsb pdb:2MZ1|rcsb pdb:3LN4|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:Fj5tiH0wrNUjTnsURIg8dB8laMg9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:Q92598 intact:EBI-6149376 intact:EBI-356829|uniprotkb:O95739|uniprotkb:Q5TBM6|uniprotkb:Q5TBM8|uniprotkb:Q9UPC4|uniprotkb:Q5TBM7|intact:EBI-2859494|uniprotkb:B4DYH1|ensembl:ENSP00000318687 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:hs105_human(display_long)|uniprotkb:HSPH1(gene name)|psi-mi:HSPH1(display_short)|uniprotkb:HSP105(gene name synonym)|uniprotkb:HSP110(gene name synonym)|uniprotkb:KIAA0201(gene name synonym)|uniprotkb:Heat shock 110 kDa protein(gene name synonym)|uniprotkb:Antigen NY-CO-25(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_001273432.1|refseq:NP_001273433.1|refseq:NP_001273434.1|refseq:NP_006635.2|ensembl:ENSG00000120694(gene)|ensembl:ENST00000320027(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051135"(positive regulation of NK T cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042053|interpro:IPR043129|mint:Q92598|rcsb pdb:6GFA|reactome:R-HSA-3000484|reactome:R-HSA-3371453 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:FSdvp2KDHLmNpceRJ9HLY5IBfQA9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:Q16537 intact:EBI-6149376 intact:EBI-968374|uniprotkb:B7ZAW5|uniprotkb:J3KQN6|ensembl:ENSP00000337641|uniprotkb:Q52LW4|uniprotkb:A4FU37|uniprotkb:B7ZKK8|intact:EBI-10962508|uniprotkb:B7ZKK9 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:2a5e_human(display_long)|uniprotkb:PPP2R5E(gene name)|psi-mi:PPP2R5E(display_short)|uniprotkb:PP2A B subunit isoform B'-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-epsilon(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000154001(gene)|ensembl:ENST00000337537(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR016024(Armadillo-type fold)|mint:Q16537|reactome:R-HSA-141444|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025|interpro:IPR011989(Armadillo-like helical)|refseq:NP_006237.1|refseq:NP_001269108.1|refseq:NP_001269109.1|refseq:NP_001269110.1|refseq:NP_001269111.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:m6vjnzx9eg+HpXrI2KKBLPbObzA9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:P42224 intact:EBI-6149376 intact:EBI-1057697|uniprotkb:Q53S88|uniprotkb:Q53XW4|uniprotkb:B2RCA0|uniprotkb:Q9UDL5|uniprotkb:A8K989|uniprotkb:D2KFR8|uniprotkb:Q68D00|uniprotkb:D3DPI7|ensembl:ENSP00000354394|ensembl:ENSP00000386244|ensembl:ENSP00000388240|ensembl:ENSP00000438703 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:stat1_human(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)|uniprotkb:Transcription factor ISGF-3 components p91/p84(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_009330.1|refseq:NP_644671.1|rcsb pdb:1YVL|rcsb pdb:2KA6|rcsb pdb:3WWT|reactome:R-HSA-1059683|reactome:R-HSA-1169408|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8939902|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9013508|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-909733|rcsb pdb:1BF5|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-912694|refseq:XP_006712781.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016922"(nuclear receptor binding)|ensembl:ENSG00000115415(gene)|ensembl:ENST00000361099(transcript)|ensembl:ENST00000409465(transcript)|ensembl:ENST00000415035(transcript)|ensembl:ENST00000540176(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051607"(defense response to virus)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0061326"(renal tubule development)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022752|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|interpro:IPR035859|interpro:IPR036535|interpro:IPR036860|interpro:IPR038295|mint:P42224|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042393"(histone binding)|dip:DIP-46140N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:a2ZnhdFZkctbjaXLpsYNJ3q5Cv49606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:P05141 intact:EBI-6149376 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:P68371 intact:EBI-6149376 intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:Q96HS1 intact:EBI-6149376 intact:EBI-713608|uniprotkb:Q96JB0|intact:EBI-2555528|ensembl:ENSP00000438465|uniprotkb:C9IZY7|uniprotkb:A9LN06 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:pgam5_human(display_long)|uniprotkb:Bcl-XL-binding protein v68(gene name synonym)|uniprotkb:PGAM5(gene name)|psi-mi:PGAM5(display_short)|uniprotkb:Phosphoglycerate mutase family member 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_001164014.1|refseq:NP_612642.2|ensembl:ENSG00000247077(gene)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016791"(phosphatase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|mint:Q96HS1|rcsb pdb:3MXO|rcsb pdb:3O0T|rcsb pdb:5MUF|rcsb pdb:6CNI|rcsb pdb:6CNL|reactome:R-HSA-8934903|ensembl:ENST00000498926(transcript)|dip:DIP-50735N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:prE0I+tNIEjN9Y1NBZbh51DY2+Q9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:P34932 intact:EBI-6149376 intact:EBI-356933|uniprotkb:O95756|uniprotkb:Q2TAL4|uniprotkb:Q9BUK9|ensembl:ENSP00000302961 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:hsp74_human(display_long)|uniprotkb:HSPA4(gene name)|psi-mi:HSPA4(display_short)|uniprotkb:APG2(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-2(gene name synonym)|uniprotkb:HSP70RY(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_002145.3|dip:DIP-460N|ensembl:ENSG00000170606(gene)|ensembl:ENST00000304858(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042052|interpro:IPR043129|mint:P34932|reactome:R-HSA-3371453 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:4OkTlG9p3IQQBYloiuHS8+t13TM9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:P49411 intact:EBI-6149376 intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:O14654 intact:EBI-6149376 intact:EBI-356594|ensembl:ENSP00000505547 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:P67775 intact:EBI-6149376 intact:EBI-712311|ensembl:ENSP00000418447|uniprotkb:P05323|uniprotkb:P13197 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:pp2aa_human(display_long)|uniprotkb:PPP2CA(gene name)|psi-mi:PPP2CA(display_short)|uniprotkb:Replication protein C(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000113575(gene)|ensembl:ENST00000481195(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007498"(mesoderm development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904526"(regulation of microtubule binding)|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P67775|rcsb pdb:2IAE|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3FGA|rcsb pdb:3K7W|rcsb pdb:3P71|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4IYP|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2995383|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|rcsb pdb:3K7V|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_002706.1|dip:DIP-29395N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:Zynydo3YUFioN2iUl6oR0nVJ4YY9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:O60884 intact:EBI-6149376 intact:EBI-352957|ensembl:ENSP00000314030|uniprotkb:O14711|uniprotkb:B2R7L7 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:dnja2_human(display_long)|uniprotkb:DNAJA2(gene name)|psi-mi:DNAJA2(display_short)|uniprotkb:HIRIP4(gene name synonym)|uniprotkb:CPR3(gene name synonym)|uniprotkb:HIRA-interacting protein 4(gene name synonym)|uniprotkb:Cell cycle progression restoration gene 3 protein(gene name synonym)|uniprotkb:Dnj3(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000069345(gene)|ensembl:ENST00000317089(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:O60884|reactome:R-HSA-3371497|interpro:IPR018253|refseq:NP_005871.1|dip:DIP-33143N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:c+JdHn0cKVKqRZCvK6DRYWs+zkQ9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:P62829 intact:EBI-6149376 intact:EBI-353303|uniprotkb:P23131|uniprotkb:Q3SWV7|uniprotkb:P24048|uniprotkb:Q29246|uniprotkb:Q6P5S1|ensembl:ENSP00000377865|ensembl:ENSP00000420311 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:rl23_human(display_long)|uniprotkb:RPL23(gene name)|psi-mi:RPL23(display_short)|uniprotkb:60S ribosomal protein L17(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|reactome:R-HSA-9010553|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|refseq:NP_000969.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000218(Ribosomal protein L14b/L23e)|interpro:IPR019972|interpro:IPR036853|mint:P62829|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|ensembl:ENSG00000125691(gene)|ensembl:ENST00000394332(transcript)|ensembl:ENST00000479035(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0005730"(nucleolus)|dip:DIP-33156N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:TiSVU2W4+lkwf12eb4+vG6IFlZA9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:P68104 intact:EBI-6149376 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:P63244 intact:EBI-6149376 intact:EBI-296739|ensembl:ENSP00000426909|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-923003|uniprotkb:B3KTJ0|uniprotkb:Q53HU2|uniprotkb:Q5J8M6|uniprotkb:Q5VLR4|uniprotkb:Q6FH47|intact:EBI-2559282|uniprotkb:D3DWS0 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:rack1_human(display_long)|uniprotkb:Small ribosomal subunit protein RACK1(gene name synonym)|uniprotkb:HLC7(orf name)|uniprotkb:PIG21(orf name)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:Cell proliferation-inducing gene 21 protein(gene name synonym)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-like protein 12.3(gene name synonym)|uniprotkb:Human lung cancer oncogene 7 protein(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) rcsb pdb:4AOW|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|mint:P63244|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|ensembl:ENSG00000204628(gene)|ensembl:ENST00000512805(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5626978|rcsb pdb:6ZUO|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|go:"GO:0060090"(molecular adaptor activity)|refseq:NP_006089.1|dip:DIP-46736N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:P62701 intact:EBI-6149376 intact:EBI-354303|uniprotkb:P12631|uniprotkb:P12750|uniprotkb:P27576|uniprotkb:Q14727|uniprotkb:P55831|uniprotkb:Q6IPY4|ensembl:ENSP00000362744 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:rs4x_human(display_long)|uniprotkb:RPS4X(gene name)|psi-mi:RPS4X(display_short)|uniprotkb:CCG2(gene name synonym)|uniprotkb:RPS4(gene name synonym)|uniprotkb:SCAR(gene name synonym)|uniprotkb:Single copy abundant mRNA protein(gene name synonym)|uniprotkb:SCR10(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_000998.1|rcsb pdb:6OLI|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000198034(gene)|ensembl:ENST00000316084(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000876(Ribosomal protein S4e)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005824(KOW)|interpro:IPR013843(Ribosomal protein S4e, N-terminal)|interpro:IPR013845(Ribosomal protein S4e, central)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR018199|interpro:IPR032277|interpro:IPR036986|interpro:IPR038237|interpro:IPR041982|mint:P62701|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|go:"GO:0045727"(positive regulation of translation)|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:2ZuLXqBSDkK0CtN3mnIDoFAR8yI9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:Q5VTE0 intact:EBI-6149376 intact:EBI-877809 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:ef1a3_human(display_long)|uniprotkb:EEF1A1P5(gene name)|psi-mi:EEF1A1P5(display_short)|uniprotkb:Eukaryotic elongation factor 1 A-like 3(gene name synonym)|uniprotkb:EEF1AL3(gene name synonym)|uniprotkb:Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR031157|reactome:R-HSA-156842|interpro:IPR027417 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:3t6tj3i+3CKTC1NsrHyBkeoRK789606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:P30153 intact:EBI-6149376 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:P62269 intact:EBI-6149376 intact:EBI-352451|ensembl:ENSP00000211372|ensembl:ENSP00000393241|ensembl:ENSP00000403175|ensembl:ENSP00000412583|ensembl:ENSP00000416110|uniprotkb:P25232|uniprotkb:Q6IPF8|uniprotkb:Q5SUJ3 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:rs18_human(display_long)|uniprotkb:RPS18(gene name)|psi-mi:RPS18(display_short)|uniprotkb:D6S218E(gene name synonym)|uniprotkb:Ke-3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS13(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_072045.1|ensembl:ENSG00000096150(gene)|ensembl:ENSG00000223367(gene)|ensembl:ENSG00000226225(gene)|ensembl:ENSG00000231500(gene)|ensembl:ENSG00000235650(gene)|ensembl:ENST00000211372(transcript)|ensembl:ENST00000434122(transcript)|ensembl:ENST00000439602(transcript)|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENST00000454021(transcript)|ensembl:ENST00000457341(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001892(Ribosomal protein S13)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR018269|interpro:IPR027437|mint:P62269|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|dip:DIP-32892N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:yOHgKM/BuvgGdqp1OEVPeuiABg89606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:P53007 intact:EBI-6149376 intact:EBI-359163|uniprotkb:Q9BSK6|uniprotkb:A8K8E8|ensembl:ENSP00000215882 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:txtp_human(display_long)|uniprotkb:SLC25A1(gene name)|psi-mi:SLC25A1(display_short)|uniprotkb:SLC20A3(gene name synonym)|uniprotkb:Citrate transport protein(gene name synonym)|uniprotkb:Tricarboxylate carrier protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_005975.1|ensembl:ENSG00000100075(gene)|ensembl:ENST00000215882(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006843"(mitochondrial citrate transmembrane transport)|go:"GO:0015137"(citrate transmembrane transporter activity)|go:"GO:0015142"(tricarboxylic acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071913"(citrate secondary active transmembrane transporter activity)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|mint:P53007|reactome:R-HSA-70263|reactome:R-HSA-75105 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:MB0RrMAQme4F8M4IivU1AqUxlgA9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:O95757 intact:EBI-6149376 intact:EBI-358652|uniprotkb:Q4W5M5|uniprotkb:Q8IWA2|uniprotkb:A2ICT2|ensembl:ENSP00000296464|ensembl:ENSP00000422482 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:hs74l_human(display_long)|uniprotkb:HSPA4L(gene name)|psi-mi:HSPA4L(display_short)|uniprotkb:APG1(gene name synonym)|uniprotkb:OSP94(gene name synonym)|uniprotkb:Osmotic stress protein 94(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-1(gene name synonym)|uniprotkb:Heat-shock protein family A member 4-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042708|interpro:IPR043129|mint:O95757|reactome:R-HSA-3371453|refseq:NP_055093.2|refseq:NP_001304310.1|refseq:NP_001304311.1|refseq:NP_001304312.1|go:"GO:0005634"(nucleus)|ensembl:ENSG00000164070(gene)|ensembl:ENST00000296464(transcript)|ensembl:ENST00000508776(transcript)|go:"GO:0005524"(ATP binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:6ZoMlI4t4A4u4YsQgrlcwAqjpi49606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q77M19 uniprotkb:Q13885 intact:EBI-6149376 intact:EBI-711595|ensembl:ENSP00000369703|uniprotkb:Q6FGZ8|uniprotkb:Q8IWR2 psi-mi:q77m19_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:tbb2a_human(display_long)|uniprotkb:TUBB2A(gene name)|psi-mi:TUBB2A(display_short)|uniprotkb:TUBB2(gene name synonym)|uniprotkb:Tubulin beta class IIa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156361|imex:IM-17331-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR028243|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding) reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-389957|reactome:R-HSA-983189|reactome:R-HSA-9668328|ensembl:ENSG00000137267(gene)|ensembl:ENST00000333628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q13885|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|refseq:NP_001060.1|refseq:NP_001297244.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:UEWGEPxRrJy17P6L6dsT/Vy7/4M132487 rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk9606 intact-crc:9C0E34B6015021DE|rigid:p5whgABw1kDotooLBhM4v9cpSH8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B9VXK6 uniprotkb:Q9BQE3 intact:EBI-6149520 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:b9vxk6_hcmvt(display_long)|uniprotkb:UL36(gene name)|psi-mi:UL36(display_short) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10363(hcmvt)|taxid:10363("Human cytomegalovirus (strain Towne)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156496|imex:IM-17331-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003360(US22-like viral protein) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:A8EWEnEc28fpSQjTEYAjOdQ6LN410363 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:A4988E709C69D57D|rigid:tYz61WzsZzmdNuXexot5f0q/a4o false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B9VXK6 uniprotkb:P50395 intact:EBI-6149520 intact:EBI-1049143|uniprotkb:O43928|uniprotkb:Q9UQM6|ensembl:ENSP00000369538|uniprotkb:Q5SX88 psi-mi:b9vxk6_hcmvt(display_long)|uniprotkb:UL36(gene name)|psi-mi:UL36(display_short) psi-mi:gdib_human(display_long)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)|uniprotkb:GDI2(gene name)|psi-mi:GDI2(display_short)|uniprotkb:RABGDIB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10363(hcmvt)|taxid:10363("Human cytomegalovirus (strain Towne)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156496|imex:IM-17331-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003360(US22-like viral protein) ensembl:ENSG00000057608(gene)|ensembl:ENST00000380191(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0034774"(secretory granule lumen)|refseq:NP_001108628.1|refseq:NP_001485.2|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50395|reactome:R-HSA-6798695|reactome:R-HSA-8876198|dip:DIP-50593N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:A8EWEnEc28fpSQjTEYAjOdQ6LN410363 rogid:KTUS915xP+QA9QFU2aZSyS+Hkgc9606 intact-crc:A4988E709C69D57D|rigid:tYz61WzsZzmdNuXexot5f0q/a4o false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B9VXK6 uniprotkb:P42677 intact:EBI-6149520 intact:EBI-356336|ensembl:ENSP00000499044|uniprotkb:Q5T4L6 psi-mi:b9vxk6_hcmvt(display_long)|uniprotkb:UL36(gene name)|psi-mi:UL36(display_short) psi-mi:rs27_human(display_long)|uniprotkb:RPS27(gene name)|psi-mi:RPS27(display_short)|uniprotkb:MPS1(gene name synonym)|uniprotkb:Metallopan-stimulin 1(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS27(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10363(hcmvt)|taxid:10363("Human cytomegalovirus (strain Towne)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156496|imex:IM-17331-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003360(US22-like viral protein) refseq:NP_001021.1|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|ensembl:ENSG00000177954(gene)|ensembl:ENST00000651669(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:P42677|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-141444|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-2500257|rcsb pdb:6OM7|reactome:R-HSA-5663220|reactome:R-HSA-6791226|reactome:R-HSA-68877|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-9648025|reactome:R-HSA-975956|reactome:R-HSA-975957|dip:DIP-44182N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:A8EWEnEc28fpSQjTEYAjOdQ6LN410363 rogid:OA5IWAJDBpY5FFdVnun7Sq/jI7g9606 intact-crc:A4988E709C69D57D|rigid:tYz61WzsZzmdNuXexot5f0q/a4o false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B9VXK6 uniprotkb:P63267 intact:EBI-6149520 intact:EBI-297795|uniprotkb:P12718|uniprotkb:Q504R1|uniprotkb:Q6FI22|ensembl:ENSP00000295137|ensembl:ENSP00000386857|uniprotkb:B2R7E7|uniprotkb:D6W5H8|uniprotkb:B4E315|uniprotkb:E9PG30 psi-mi:b9vxk6_hcmvt(display_long)|uniprotkb:UL36(gene name)|psi-mi:UL36(display_short) psi-mi:acth_human(display_long)|uniprotkb:ACTG2(gene name)|psi-mi:ACTG2(display_short)|uniprotkb:ACTA3(gene name synonym)|uniprotkb:ACTSG(gene name synonym)|uniprotkb:Smooth muscle gamma-actin(gene name synonym)|uniprotkb:Gamma-2-actin(gene name synonym)|uniprotkb:Alpha-actin-3(gene name synonym)|uniprotkb:ACTL3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10363(hcmvt)|taxid:10363("Human cytomegalovirus (strain Towne)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156496|imex:IM-17331-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003360(US22-like viral protein) go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0032982"(myosin filament)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:6JAT|reactome:R-HSA-445355|go:"GO:0010628"(positive regulation of gene expression)|ensembl:ENST00000345517(transcript)|ensembl:ENST00000409624(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|ensembl:ENSG00000163017(gene)|refseq:NP_001186822.1|refseq:NP_001606.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:A8EWEnEc28fpSQjTEYAjOdQ6LN410363 rogid:tp0JsXhrGsRl5i4Wg2dyaPGUPxA9606 intact-crc:A4988E709C69D57D|rigid:tYz61WzsZzmdNuXexot5f0q/a4o false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B9VXK6 uniprotkb:O95071 intact:EBI-6149520 intact:EBI-358329|uniprotkb:O94970|uniprotkb:Q9NPL3|ensembl:ENSP00000429084|uniprotkb:B2RP24|intact:EBI-10967451|uniprotkb:J3KMW7 psi-mi:b9vxk6_hcmvt(display_long)|uniprotkb:UL36(gene name)|psi-mi:UL36(display_short) psi-mi:ubr5_human(display_long)|uniprotkb:UBR5(gene name)|psi-mi:UBR5(display_short)|uniprotkb:HYD(gene name synonym)|uniprotkb:KIAA0896(gene name synonym)|uniprotkb:EDD(gene name synonym)|uniprotkb:EDD1(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase, HECT domain-containing 1(gene name synonym)|uniprotkb:Hyperplastic discs protein homolog(gene name synonym)|uniprotkb:Progestin-induced protein(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase UBR5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10363(hcmvt)|taxid:10363("Human cytomegalovirus (strain Towne)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156496|imex:IM-17331-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003360(US22-like viral protein) refseq:NP_001269802.1|ensembl:ENST00000520539(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|ensembl:ENSG00000104517(gene)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR024725|interpro:IPR035983|interpro:IPR036053|mint:O95071|rcsb pdb:1I2T|rcsb pdb:2QHO|refseq:NP_056986.2|rcsb pdb:3PT3|dip:DIP-32930N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:A8EWEnEc28fpSQjTEYAjOdQ6LN410363 rogid:5yiXAYJbV4iA8d3btwaVfL7vaik9606 intact-crc:A4988E709C69D57D|rigid:tYz61WzsZzmdNuXexot5f0q/a4o false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B9VXK6 uniprotkb:B2RTY4 intact:EBI-6149520 intact:EBI-355398|uniprotkb:B0I1T5|uniprotkb:Q14787|uniprotkb:Q3YLD7|uniprotkb:Q3YLD8|uniprotkb:Q6P986|uniprotkb:Q9H8T5|uniprotkb:Q9NTG2|uniprotkb:Q9NUY2|uniprotkb:Q9UEP3|intact:EBI-720284|uniprotkb:Q9UNJ2|uniprotkb:C9IYB3|uniprotkb:C9JA86|intact:EBI-28974247|ensembl:ENSP00000348349|ensembl:ENSP00000398250 psi-mi:b9vxk6_hcmvt(display_long)|uniprotkb:UL36(gene name)|psi-mi:UL36(display_short) psi-mi:myo9a_human(display_long)|uniprotkb:MYO9A(gene name)|psi-mi:MYO9A(display_short)|uniprotkb:MYR7(gene name synonym)|uniprotkb:Unconventional myosin-9a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10363(hcmvt)|taxid:10363("Human cytomegalovirus (strain Towne)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156496|imex:IM-17331-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003360(US22-like viral protein) refseq:NP_008832.2|ensembl:ENSP00000348349|ensembl:ENST00000424560|ensembl:ENSP00000399162|ensembl:ENSP00000398250|refseq:XP_006720602.1|ensembl:ENSG00000066933(gene)|ensembl:ENST00000356056(transcript)|ensembl:ENST00000444904(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0007601"(visual perception)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0034329"(cell junction assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028558|interpro:IPR029071|interpro:IPR036023|interpro:IPR036961|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013424 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:A8EWEnEc28fpSQjTEYAjOdQ6LN410363 rogid:xiEo+vK0qu9k1RrBjoOrgp7Wm+g9606 intact-crc:A4988E709C69D57D|rigid:tYz61WzsZzmdNuXexot5f0q/a4o false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B9VXK6 uniprotkb:P11021 intact:EBI-6149520 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:b9vxk6_hcmvt(display_long)|uniprotkb:UL36(gene name)|psi-mi:UL36(display_short) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10363(hcmvt)|taxid:10363("Human cytomegalovirus (strain Towne)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156496|imex:IM-17331-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003360(US22-like viral protein) ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:A8EWEnEc28fpSQjTEYAjOdQ6LN410363 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 intact-crc:A4988E709C69D57D|rigid:tYz61WzsZzmdNuXexot5f0q/a4o false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B9VXK6 uniprotkb:P12036 intact:EBI-6149520 intact:EBI-2880271|uniprotkb:Q9UQ14|uniprotkb:Q9UJS7|uniprotkb:Q96HF8|uniprotkb:B4DYY4|ensembl:ENSP00000311997 psi-mi:b9vxk6_hcmvt(display_long)|uniprotkb:UL36(gene name)|psi-mi:UL36(display_short) psi-mi:nfh_human(display_long)|uniprotkb:NEFH(gene name)|psi-mi:NEFH(display_short)|uniprotkb:KIAA0845(gene name synonym)|uniprotkb:NFH(gene name synonym)|uniprotkb:200 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament triplet H protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10363(hcmvt)|taxid:10363("Human cytomegalovirus (strain Towne)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156496|imex:IM-17331-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003360(US22-like viral protein) refseq:NP_066554.2|ensembl:ENSG00000100285(gene)|ensembl:ENST00000310624(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005883"(neurofilament)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0061564"(axon development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR010790(Protein of unknown function DUF1388)|interpro:IPR018039|interpro:IPR033183|interpro:IPR039008|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:A8EWEnEc28fpSQjTEYAjOdQ6LN410363 rogid:TXMrn6SWBHIYQY1loZfVvMo9PtU9606 intact-crc:A4988E709C69D57D|rigid:tYz61WzsZzmdNuXexot5f0q/a4o false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B9VXK6 uniprotkb:P07437 intact:EBI-6149520 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:b9vxk6_hcmvt(display_long)|uniprotkb:UL36(gene name)|psi-mi:UL36(display_short) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10363(hcmvt)|taxid:10363("Human cytomegalovirus (strain Towne)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156496|imex:IM-17331-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003360(US22-like viral protein) refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:A8EWEnEc28fpSQjTEYAjOdQ6LN410363 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:A4988E709C69D57D|rigid:tYz61WzsZzmdNuXexot5f0q/a4o false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B9VXK6 uniprotkb:Q14790 intact:EBI-6149520 intact:EBI-78060|ensembl:ENSP00000412523|ensembl:ENSP00000501268|uniprotkb:Q14793|uniprotkb:Q14794|uniprotkb:Q14795|uniprotkb:Q14796|uniprotkb:Q15780|uniprotkb:Q15806|uniprotkb:Q53TT5|uniprotkb:Q8TDI1|uniprotkb:Q8TDI2|uniprotkb:Q8TDI3|uniprotkb:Q8TDI4|uniprotkb:Q8TDI5|uniprotkb:Q96T22|uniprotkb:Q9C0K4|uniprotkb:O14676|uniprotkb:Q14791|uniprotkb:Q14792|uniprotkb:Q9UQ81 psi-mi:b9vxk6_hcmvt(display_long)|uniprotkb:UL36(gene name)|psi-mi:UL36(display_short) psi-mi:casp8_human(display_long)|uniprotkb:CASP8(gene name)|psi-mi:CASP8(display_short)|uniprotkb:MCH5(gene name synonym)|uniprotkb:ICE-like apoptotic protease 5(gene name synonym)|uniprotkb:MORT1-associated ced-3 homolog(gene name synonym)|uniprotkb:FADD-homologous ICE/ced-3-like protease(gene name synonym)|uniprotkb:FADD-like ICE(gene name synonym)|uniprotkb:Apoptotic cysteine protease(gene name synonym)|uniprotkb:Apoptotic protease Mch-5(gene name synonym)|uniprotkb:CAP4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10363(hcmvt)|taxid:10363("Human cytomegalovirus (strain Towne)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156496|imex:IM-17331-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003360(US22-like viral protein) go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007507"(heart development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|ensembl:ENSG00000064012(gene)|ensembl:ENST00000432109(transcript)|ensembl:ENST00000673742(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0009409"(response to cold)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031265"(CD95 death-inducing signaling complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032025"(response to cobalt ion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035877"(death effector domain binding)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046677"(response to antibiotic)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0070269"(pyroptosis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0097264"(self proteolysis)|go:"GO:0097342"(ripoptosome)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|reactome:R-HSA-264870|interpro:IPR001875(Death effector)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR033170|mint:Q14790|rcsb pdb:1F9E|rcsb pdb:1I4E|rcsb pdb:1QDU|rcsb pdb:1QTN|rcsb pdb:2C2Z|rcsb pdb:2FUN|rcsb pdb:2K7Z|rcsb pdb:2Y1L|rcsb pdb:3H11|rcsb pdb:3KJN|rcsb pdb:3KJQ|rcsb pdb:4JJ7|rcsb pdb:4PRZ|rcsb pdb:4PS1|rcsb pdb:4ZBW|rcsb pdb:5H31|rcsb pdb:5H33|rcsb pdb:5JQE|rcsb pdb:5L08|rcsb pdb:6AGW|rcsb pdb:6PX9|reactome:R-HSA-111465|reactome:R-HSA-140534|reactome:R-HSA-168638|reactome:R-HSA-2562578|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5660668|reactome:R-HSA-5675482|reactome:R-HSA-69416|reactome:R-HSA-75108|reactome:R-HSA-75153|reactome:R-HSA-75157|reactome:R-HSA-75158|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-9686347|reactome:R-HSA-9693928|refseq:NP_001073593.1|refseq:NP_001073594.1|refseq:NP_001219.2|refseq:NP_203519.1|refseq:NP_203520.1|refseq:NP_203522.1|refseq:XP_006712852.1|refseq:XP_006712853.1|refseq:XP_006712856.1|refseq:XP_005246944.1|refseq:XP_005246945.1|refseq:XP_005246946.1|refseq:XP_005246947.1|refseq:XP_005246948.1|refseq:XP_005246949.1|refseq:XP_005246943.1|dip:DIP-30915N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:A8EWEnEc28fpSQjTEYAjOdQ6LN410363 rogid:XKI9lMiIKZTtoY2lN/QIm1yTksY9606 intact-crc:A4988E709C69D57D|rigid:tYz61WzsZzmdNuXexot5f0q/a4o false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B9VXK6 uniprotkb:O14654 intact:EBI-6149520 intact:EBI-356594|ensembl:ENSP00000505547 psi-mi:b9vxk6_hcmvt(display_long)|uniprotkb:UL36(gene name)|psi-mi:UL36(display_short) psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10363(hcmvt)|taxid:10363("Human cytomegalovirus (strain Towne)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156496|imex:IM-17331-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003360(US22-like viral protein) ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:A8EWEnEc28fpSQjTEYAjOdQ6LN410363 rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606 intact-crc:A4988E709C69D57D|rigid:tYz61WzsZzmdNuXexot5f0q/a4o false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B9VXK6 uniprotkb:Q9NVI7 intact:EBI-6149520 intact:EBI-352007|ensembl:ENSP00000368030|uniprotkb:Q5SV23|uniprotkb:Q8N275|uniprotkb:Q96A50|uniprotkb:B3KPB3|uniprotkb:D2K8Q1|uniprotkb:G3V1I6 psi-mi:b9vxk6_hcmvt(display_long)|uniprotkb:UL36(gene name)|psi-mi:UL36(display_short) psi-mi:atd3a_human(display_long)|uniprotkb:ATAD3A(gene name)|psi-mi:ATAD3A(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10363(hcmvt)|taxid:10363("Human cytomegalovirus (strain Towne)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156496|imex:IM-17331-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003360(US22-like viral protein) refseq:NP_001164006.1|refseq:NP_001164007.1|refseq:NP_060658.3|ensembl:ENSG00000197785(gene)|ensembl:ENST00000378755(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q9NVI7|dip:DIP-33194N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:A8EWEnEc28fpSQjTEYAjOdQ6LN410363 rogid:IZKJEVLLS/DFINgBgO5frizN1P49606 intact-crc:A4988E709C69D57D|rigid:tYz61WzsZzmdNuXexot5f0q/a4o false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B9VXK6 uniprotkb:P55795 intact:EBI-6149520 intact:EBI-352823|ensembl:ENSP00000361927|uniprotkb:Q9HHA7|uniprotkb:A1L400 psi-mi:b9vxk6_hcmvt(display_long)|uniprotkb:UL36(gene name)|psi-mi:UL36(display_short) psi-mi:hnrh2_human(display_long)|uniprotkb:HNRNPH2(gene name)|psi-mi:HNRNPH2(display_short)|uniprotkb:FTP3(gene name synonym)|uniprotkb:HNRPH2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein H'(gene name synonym)|uniprotkb:FTP-3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10363(hcmvt)|taxid:10363("Human cytomegalovirus (strain Towne)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156496|imex:IM-17331-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003360(US22-like viral protein) ensembl:ENSG00000126945(gene)|ensembl:ENST00000316594(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P55795|rcsb pdb:1WEZ|rcsb pdb:1WG5|rcsb pdb:6DG1|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001027565.1|refseq:NP_062543.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:A8EWEnEc28fpSQjTEYAjOdQ6LN410363 rogid:811j5syFsbk/QSaZv/ag9QsFUEQ9606 intact-crc:A4988E709C69D57D|rigid:tYz61WzsZzmdNuXexot5f0q/a4o false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B9VXK6 uniprotkb:Q71UM5 intact:EBI-6149520 intact:EBI-355126|uniprotkb:Q9BTJ1|ensembl:ENSP00000331019 psi-mi:b9vxk6_hcmvt(display_long)|uniprotkb:UL36(gene name)|psi-mi:UL36(display_short) psi-mi:rs27l_human(display_long)|uniprotkb:RPS27L(gene name)|psi-mi:RPS27L(display_short)|uniprotkb:Small ribosomal subunit protein eS27-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10363(hcmvt)|taxid:10363("Human cytomegalovirus (strain Towne)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156496|imex:IM-17331-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003360(US22-like viral protein) refseq:NP_057004.1|ensembl:ENSG00000185088(gene)|ensembl:ENST00000330964(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0006412"(translation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008494"(translation activator activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:Q71UM5|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:A8EWEnEc28fpSQjTEYAjOdQ6LN410363 rogid:OVIAlDF6dN3DxLZgQFrFl8r0Z0I9606 intact-crc:A4988E709C69D57D|rigid:tYz61WzsZzmdNuXexot5f0q/a4o false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B9VXK6 uniprotkb:Q9NUL7 intact:EBI-6149520 intact:EBI-2560229|ensembl:ENSP00000332340 psi-mi:b9vxk6_hcmvt(display_long)|uniprotkb:UL36(gene name)|psi-mi:UL36(display_short) psi-mi:ddx28_human(display_long)|uniprotkb:DDX28(gene name)|psi-mi:DDX28(display_short)|uniprotkb:MDDX28(gene name synonym)|uniprotkb:Mitochondrial DEAD box protein 28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10363(hcmvt)|taxid:10363("Human cytomegalovirus (strain Towne)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156496|imex:IM-17331-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003360(US22-like viral protein) refseq:NP_060850.2|ensembl:ENSG00000182810(gene)|ensembl:ENST00000332395(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0019843"(rRNA binding)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902775"(mitochondrial large ribosomal subunit assembly)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:A8EWEnEc28fpSQjTEYAjOdQ6LN410363 rogid:aq2jUV+jvcoBIROUedWr86FxEl89606 intact-crc:A4988E709C69D57D|rigid:tYz61WzsZzmdNuXexot5f0q/a4o false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B9VXK6 uniprotkb:Q71U36 intact:EBI-6149520 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:b9vxk6_hcmvt(display_long)|uniprotkb:UL36(gene name)|psi-mi:UL36(display_short) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10363(hcmvt)|taxid:10363("Human cytomegalovirus (strain Towne)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156496|imex:IM-17331-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003360(US22-like viral protein) refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:A8EWEnEc28fpSQjTEYAjOdQ6LN410363 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 intact-crc:A4988E709C69D57D|rigid:tYz61WzsZzmdNuXexot5f0q/a4o false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B9VXK6 uniprotkb:Q70EL1 intact:EBI-6149520 intact:EBI-946185|intact:EBI-2798236|uniprotkb:B9ZVM1|uniprotkb:A1L4Q4|uniprotkb:A3KFK3|uniprotkb:A3KFK5|uniprotkb:A3KFK6|uniprotkb:A3KFK7|uniprotkb:A6PVS4|uniprotkb:A6PVS5|uniprotkb:A6PVS6|uniprotkb:A6PVS7|uniprotkb:B3KVY1|uniprotkb:Q5F2F4|uniprotkb:Q6ZSP1|uniprotkb:Q6ZSR1|uniprotkb:Q6ZTM0|uniprotkb:Q8N1X2|uniprotkb:Q6P1N6|ensembl:ENSP00000345216 psi-mi:b9vxk6_hcmvt(display_long)|uniprotkb:UL36(gene name)|psi-mi:UL36(display_short) psi-mi:ubp54_human(display_long)|uniprotkb:C10orf29(gene name synonym)|uniprotkb:Inactive ubiquitin-specific peptidase 54(gene name synonym)|uniprotkb:USP54(gene name)|psi-mi:USP54(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10363(hcmvt)|taxid:10363("Human cytomegalovirus (strain Towne)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156496|imex:IM-17331-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003360(US22-like viral protein) refseq:NP_689799.3|refseq:NP_001307366.1|refseq:XP_016871263.1|refseq:XP_016871264.1|refseq:XP_016871265.1|refseq:XP_016871266.1|ensembl:ENSG00000166348(gene)|ensembl:ENST00000339859(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR028889|interpro:IPR038765|interpro:IPR040142|mint:Q70EL1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:A8EWEnEc28fpSQjTEYAjOdQ6LN410363 rogid:TwMLO8uUiZ6onr+jyUz5D6qwZ1g9606 intact-crc:A4988E709C69D57D|rigid:tYz61WzsZzmdNuXexot5f0q/a4o false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B9VXK6 uniprotkb:P62736 intact:EBI-6149520 intact:EBI-698810|uniprotkb:P03996|uniprotkb:P04108|uniprotkb:Q6FI19|uniprotkb:B2R8A4|ensembl:ENSP00000224784 psi-mi:b9vxk6_hcmvt(display_long)|uniprotkb:UL36(gene name)|psi-mi:UL36(display_short) psi-mi:acta_human(display_long)|uniprotkb:Alpha-actin-2(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 46 protein(gene name synonym)|uniprotkb:ACTA2(gene name)|psi-mi:ACTA2(display_short)|uniprotkb:ACTSA(gene name synonym)|uniprotkb:ACTVS(gene name synonym)|uniprotkb:GIG46(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10363(hcmvt)|taxid:10363("Human cytomegalovirus (strain Towne)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156496|imex:IM-17331-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003360(US22-like viral protein) refseq:NP_001135417.1|refseq:NP_001604.1|refseq:NP_001307784.1|ensembl:ENSG00000107796(gene)|ensembl:ENST00000224784(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014829"(vascular associated smooth muscle contraction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072144"(glomerular mesangial cell development)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P62736|reactome:R-HSA-445355|reactome:R-HSA-9013695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:A8EWEnEc28fpSQjTEYAjOdQ6LN410363 rogid:mRZGUdL/jBuj6nVHtxoasZuA7yA9606 intact-crc:A4988E709C69D57D|rigid:tYz61WzsZzmdNuXexot5f0q/a4o false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:B9VXK6 uniprotkb:P61026 intact:EBI-6149520 intact:EBI-726075|uniprotkb:O88386|uniprotkb:Q6IA52|uniprotkb:Q9D7X6|uniprotkb:Q9H0T3|uniprotkb:D6W538|ensembl:ENSP00000264710 psi-mi:b9vxk6_hcmvt(display_long)|uniprotkb:UL36(gene name)|psi-mi:UL36(display_short) psi-mi:rab10_human(display_long)|uniprotkb:RAB10(gene name)|psi-mi:RAB10(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10363(hcmvt)|taxid:10363("Human cytomegalovirus (strain Towne)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156496|imex:IM-17331-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003360(US22-like viral protein) refseq:NP_057215.3|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031489"(myosin V binding)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0097051"(establishment of protein localization to endoplasmic reticulum membrane)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:5LPN|rcsb pdb:5SZJ|reactome:R-HSA-1445148|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000084733(gene)|ensembl:ENST00000264710(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:A8EWEnEc28fpSQjTEYAjOdQ6LN410363 rogid:ZbfLtWtXl3z6/MYyhiZp6P1Y5tE9606 intact-crc:A4988E709C69D57D|rigid:tYz61WzsZzmdNuXexot5f0q/a4o false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q82506 uniprotkb:P34931 intact:EBI-6149498 intact:EBI-354912|uniprotkb:O75634|uniprotkb:Q2HXR3|uniprotkb:Q8NE72|uniprotkb:A6NNB0|uniprotkb:Q96QC9|uniprotkb:Q9UQM1|uniprotkb:B0UXW8|ensembl:ENSP00000364805|ensembl:ENSP00000372881|ensembl:ENSP00000396486|ensembl:ENSP00000408347 psi-mi:ns1_i33a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hs71l_human(display_long)|uniprotkb:HSPA1L(gene name)|psi-mi:HSPA1L(display_short)|uniprotkb:Heat shock 70 kDa protein 1-Hom(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156481|imex:IM-17331-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-60861N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064 refseq:NP_005518.3|ensembl:ENSG00000204390(gene)|ensembl:ENSG00000206383(gene)|ensembl:ENSG00000234258(gene)|ensembl:ENSG00000236251(gene)|ensembl:ENST00000375654(transcript)|ensembl:ENST00000383390(transcript)|ensembl:ENST00000417601(transcript)|ensembl:ENST00000456772(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0072562"(blood microparticle)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P34931|rcsb pdb:3GDQ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:MUZC+RgMkeOaNXYbbKi2RfXyVsw381518 rogid:KS02DcMpD2sxSF36hUjKiSdYi4c9606 intact-crc:226102B397D65C09|rigid:9IzRCiX/ctGv+dp4FTekxlj2GYc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q82506 uniprotkb:O00459 intact:EBI-6149498 intact:EBI-346930|uniprotkb:Q5EAT5|uniprotkb:Q9UPH9|intact:EBI-28974273|ensembl:ENSP00000222254 psi-mi:ns1_i33a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:p85b_human(display_long)|uniprotkb:PIK3R2(gene name)|psi-mi:PIK3R2(display_short)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156481|imex:IM-17331-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-60861N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064 ensembl:ENSP00000222254|refseq:NP_005018.1|dip:DIP-31811N|ensembl:ENSG00000105647(gene)|ensembl:ENST00000222254(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|rcsb pdb:6OX7|rcsb pdb:6U28|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-186763|reactome:R-HSA-198203|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|mint:O00459|rcsb pdb:2KT1|rcsb pdb:2XS6|rcsb pdb:3MTT|rcsb pdb:3O5Z|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-210993|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9013409 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:MUZC+RgMkeOaNXYbbKi2RfXyVsw381518 rogid:Ij0WS0eKPwShgFWQc7OEss7AcAU9606 intact-crc:226102B397D65C09|rigid:9IzRCiX/ctGv+dp4FTekxlj2GYc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q82506 uniprotkb:O14654 intact:EBI-6149498 intact:EBI-356594|ensembl:ENSP00000505547 psi-mi:ns1_i33a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:381518(i33a0)|taxid:381518("Influenza A virus (strain A/Wilson-Smith/1933 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156481|imex:IM-17331-32 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-60861N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064 ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:MUZC+RgMkeOaNXYbbKi2RfXyVsw381518 rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606 intact-crc:226102B397D65C09|rigid:9IzRCiX/ctGv+dp4FTekxlj2GYc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9IBY5 uniprotkb:Q71U36 intact:EBI-6149651 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:q9iby5_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156625|imex:IM-17331-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003875(Paramyxoviridae nonstructural protein C) refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:LHKNPE1YOWg09yKPP1iO+ouQOeY132487 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 intact-crc:5B8BE755F8D12268|rigid:EBLq3BXkCmzHl52ECM5sQd+GlFg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9IBY5 uniprotkb:Q9BQE3 intact:EBI-6149651 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:q9iby5_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156625|imex:IM-17331-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003875(Paramyxoviridae nonstructural protein C) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:LHKNPE1YOWg09yKPP1iO+ouQOeY132487 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:5B8BE755F8D12268|rigid:EBLq3BXkCmzHl52ECM5sQd+GlFg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9IBY5 uniprotkb:O43809 intact:EBI-6149651 intact:EBI-355720|uniprotkb:Q6IB85|uniprotkb:Q6NE84|ensembl:ENSP00000300291 psi-mi:q9iby5_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:cpsf5_human(display_long)|uniprotkb:NUDT21(gene name)|psi-mi:NUDT21(display_short)|uniprotkb:CFIM25(gene name synonym)|uniprotkb:CPSF25(gene name synonym)|uniprotkb:CPSF5(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 25 kDa subunit(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 21(gene name synonym)|uniprotkb:Cleavage factor Im complex 25 kDa subunit(gene name synonym)|uniprotkb:Nudix hydrolase 21(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156625|imex:IM-17331-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003875(Paramyxoviridae nonstructural protein C) refseq:NP_008937.1|ensembl:ENSG00000167005(gene)|ensembl:ENST00000300291(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006397"(mRNA processing)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031439"(positive regulation of mRNA cleavage)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2000975"(positive regulation of pro-B cell differentiation)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR016706(Cleavage and polyadenylation specificity factor, 25 kDa subunit)|mint:O43809|rcsb pdb:2CL3|rcsb pdb:2J8Q|rcsb pdb:3BAP|rcsb pdb:3BHO|rcsb pdb:3MDG|rcsb pdb:3MDI|rcsb pdb:3N9U|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:5R4P|rcsb pdb:5R4Q|rcsb pdb:5R4R|rcsb pdb:5R4S|rcsb pdb:5R4T|rcsb pdb:5R4U|rcsb pdb:5R64|rcsb pdb:5R65|rcsb pdb:5R66|rcsb pdb:5R67|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-42502N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:LHKNPE1YOWg09yKPP1iO+ouQOeY132487 rogid:Acad4mYVuS+Eox+X2CH8PYUkGAA9606 intact-crc:5B8BE755F8D12268|rigid:EBLq3BXkCmzHl52ECM5sQd+GlFg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9IBY5 uniprotkb:Q16630 intact:EBI-6149651 intact:EBI-358410|uniprotkb:Q53ES1|uniprotkb:Q9BSJ7|uniprotkb:Q9BW18|intact:EBI-740029|uniprotkb:A8K7K9|ensembl:ENSP00000391774 psi-mi:q9iby5_measw(display_long)|uniprotkb:P(gene name)|psi-mi:P(display_short) psi-mi:cpsf6_human(display_long)|uniprotkb:CPSF6(gene name)|psi-mi:CPSF6(display_short)|uniprotkb:CFIM68(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 68 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym)|uniprotkb:Protein HPBRII-4/7(gene name synonym)|uniprotkb:Cleavage factor Im complex 68 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:132487(measw)|taxid:132487("Measles virus (strain Edmonston-Schwarz vaccine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156625|imex:IM-17331-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR003875(Paramyxoviridae nonstructural protein C) refseq:NP_008938.2|refseq:NP_001287876.1|ensembl:ENSG00000111605(gene)|ensembl:ENST00000435070(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005737"(cytoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0035061"(interchromatin granule)|go:"GO:0042382"(paraspeckles)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990448"(exon-exon junction complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034769|interpro:IPR034772|interpro:IPR035979|mint:Q16630|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:4B4N|rcsb pdb:4U0A|rcsb pdb:4U0B|rcsb pdb:4WYM|rcsb pdb:6AY9|rcsb pdb:6GX9|reactome:R-HSA-1839117|reactome:R-HSA-5655302|dip:DIP-34501N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:LHKNPE1YOWg09yKPP1iO+ouQOeY132487 rogid:nvZBuI+X/m+5MGIsfh2ToVe5nFs9606 intact-crc:5B8BE755F8D12268|rigid:EBLq3BXkCmzHl52ECM5sQd+GlFg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P04908 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156559|imex:IM-17331-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:4Qno1mMYZB6FdNoojrzulWLVq849606 intact-crc:6A1177800B2002E7|rigid:TsiYMkLL4xOZEg5UMyM3MY2qdjY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P22626 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156559|imex:IM-17331-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606 intact-crc:6A1177800B2002E7|rigid:TsiYMkLL4xOZEg5UMyM3MY2qdjY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q9BTM1 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-4398590|uniprotkb:Q9NV63|ensembl:ENSP00000373730|ensembl:ENSP00000438553 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2aj_human(display_long)|uniprotkb:H2AJ(gene name)|psi-mi:H2AJ(display_short)|uniprotkb:H2AFJ(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156559|imex:IM-17331-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_808760.1|ensembl:ENSG00000246705(gene)|ensembl:ENST00000389078(transcript)|ensembl:ENST00000544848(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:4EDU|rcsb pdb:6K60|rcsb pdb:6KVD|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-8939236 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:g6br63FeM17yJRfQI3GnmoM0vbc9606 intact-crc:6A1177800B2002E7|rigid:TsiYMkLL4xOZEg5UMyM3MY2qdjY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P30050 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-352743|uniprotkb:Q6PB27|uniprotkb:Q5VVV2|ensembl:ENSP00000354739 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:rl12_human(display_long)|uniprotkb:RPL12(gene name)|psi-mi:RPL12(display_short)|uniprotkb:Large ribosomal subunit protein uL11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156559|imex:IM-17331-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_000967.1|ensembl:ENSG00000197958(gene)|ensembl:ENST00000361436(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|interpro:IPR000911(Ribosomal protein L11)|interpro:IPR020783|interpro:IPR020784|interpro:IPR020785|interpro:IPR036769|interpro:IPR036796|mint:P30050|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:TNPEtl60cILofaPzUznvZiw6D7E9606 intact-crc:6A1177800B2002E7|rigid:TsiYMkLL4xOZEg5UMyM3MY2qdjY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P12036 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-2880271|uniprotkb:Q9UQ14|uniprotkb:Q9UJS7|uniprotkb:Q96HF8|uniprotkb:B4DYY4|ensembl:ENSP00000311997 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:nfh_human(display_long)|uniprotkb:NEFH(gene name)|psi-mi:NEFH(display_short)|uniprotkb:KIAA0845(gene name synonym)|uniprotkb:NFH(gene name synonym)|uniprotkb:200 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament triplet H protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156559|imex:IM-17331-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_066554.2|ensembl:ENSG00000100285(gene)|ensembl:ENST00000310624(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005883"(neurofilament)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0061564"(axon development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR010790(Protein of unknown function DUF1388)|interpro:IPR018039|interpro:IPR033183|interpro:IPR039008|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:TXMrn6SWBHIYQY1loZfVvMo9PtU9606 intact-crc:6A1177800B2002E7|rigid:TsiYMkLL4xOZEg5UMyM3MY2qdjY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q7L7L0 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-5325551|ensembl:ENSP00000355656|ensembl:ENSP00000493926|uniprotkb:B2R4S4 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2a3_human(display_long)|uniprotkb:H2AW(gene name)|psi-mi:H2AW(display_short)|uniprotkb:HIST3H2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156559|imex:IM-17331-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP ensembl:ENSG00000181218(gene)|ensembl:ENSG00000284841(gene)|ensembl:ENST00000366695(transcript)|refseq:NP_254280.1|ensembl:ENST00000645741(transcript)|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-5689603|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q7L7L0|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000786"(nucleosome)|dip:DIP-48936N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:t0RdR1SmUtmwRjtCS3uTyLGqSUI9606 intact-crc:6A1177800B2002E7|rigid:TsiYMkLL4xOZEg5UMyM3MY2qdjY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P62805 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156559|imex:IM-17331-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:6A1177800B2002E7|rigid:TsiYMkLL4xOZEg5UMyM3MY2qdjY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P63167 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156559|imex:IM-17331-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606 intact-crc:6A1177800B2002E7|rigid:TsiYMkLL4xOZEg5UMyM3MY2qdjY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P05386 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-354582|uniprotkb:A6NIB2|ensembl:ENSP00000346037 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:rla1_human(display_long)|uniprotkb:RPLP1(gene name)|psi-mi:RPLP1(display_short)|uniprotkb:RRP1(gene name synonym)|uniprotkb:Large ribosomal subunit protein P1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156559|imex:IM-17331-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_000994.1|refseq:NP_998890.1|ensembl:ENSG00000137818(gene)|ensembl:ENST00000260379(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR027534|interpro:IPR038716|mint:P05386|rcsb pdb:2LBF|rcsb pdb:4BEH|rcsb pdb:4V6X|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:rHSXz4ZCJy+JH6OrjUgHiTK85mo9606 intact-crc:6A1177800B2002E7|rigid:TsiYMkLL4xOZEg5UMyM3MY2qdjY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q93077 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-725259|uniprotkb:O00775|uniprotkb:O00776|uniprotkb:O00777|uniprotkb:O00778|uniprotkb:Q540R1|uniprotkb:B2R4F7|ensembl:ENSP00000321389|ensembl:ENSP00000367022|ensembl:ENSP00000473534 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2a1c_human(display_long)|uniprotkb:H2AC6(gene name)|psi-mi:H2AC6(display_short)|uniprotkb:H2A-clustered histone 6(gene name synonym)|uniprotkb:H2AFL(gene name synonym)|uniprotkb:HIST1H2AC(gene name synonym)|uniprotkb:Histone H2A/l(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156559|imex:IM-17331-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_003503.1|ensembl:ENSG00000180573(gene)|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENST00000314088(transcript)|ensembl:ENST00000377791(transcript)|ensembl:ENST00000602637(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|rcsb pdb:6C0W|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:7A08|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|interpro:IPR032458 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:m00IdooZksbNGKHSsaVvGFVpcko9606 intact-crc:6A1177800B2002E7|rigid:TsiYMkLL4xOZEg5UMyM3MY2qdjY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q96KK5 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-6147668|ensembl:ENSP00000366679 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2a1h_human(display_long)|uniprotkb:H2AC12(gene name)|psi-mi:H2AC12(display_short)|uniprotkb:H2A-clustered histone 12(gene name synonym)|uniprotkb:HIST1H2AH(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:Histone H2A/s(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156559|imex:IM-17331-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_542163.1|dip:DIP-61699N|ensembl:ENSG00000274997(gene)|ensembl:ENST00000377459(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:Oa322n+evy8Cu0E9cWTEdYwQPKM9606 intact-crc:6A1177800B2002E7|rigid:TsiYMkLL4xOZEg5UMyM3MY2qdjY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P78537 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-348630|uniprotkb:Q6NZ45|uniprotkb:A1L4Q9|ensembl:ENSP00000447537 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:bl1s1_human(display_long)|uniprotkb:BLOC1S1(gene name)|psi-mi:BLOC1S1(display_short)|uniprotkb:BLOS1(gene name synonym)|uniprotkb:RT14(gene name synonym)|uniprotkb:GCN5L1(gene name synonym)|uniprotkb:GCN5-like protein 1(gene name synonym)|uniprotkb:Protein RT14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156559|imex:IM-17331-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_001478.2|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR009395(GCN5-like 1)|mint:P78537|reactome:R-HSA-432720|reactome:R-HSA-432722|ensembl:ENSG00000135441(gene)|ensembl:ENST00000548925(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016197"(endosomal transport)|go:"GO:0018394"(peptidyl-lysine acetylation) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:lntB3izez0HoFLPpiAtPBayt+G49606 intact-crc:6A1177800B2002E7|rigid:TsiYMkLL4xOZEg5UMyM3MY2qdjY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P0C0S8 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156559|imex:IM-17331-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606 intact-crc:6A1177800B2002E7|rigid:TsiYMkLL4xOZEg5UMyM3MY2qdjY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q16777 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-5325566|ensembl:ENSP00000332194|uniprotkb:Q6DRA7|uniprotkb:Q8IUE5 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2a2c_human(display_long)|uniprotkb:H2AC20(gene name)|psi-mi:H2AC20(display_short)|uniprotkb:H2A-clustered histone 20(gene name synonym)|uniprotkb:H2AFQ(gene name synonym)|uniprotkb:HIST2H2AC(gene name synonym)|uniprotkb:Histone H2A-GL101(gene name synonym)|uniprotkb:Histone H2A/q(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156559|imex:IM-17331-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-5689603|ensembl:ENSG00000184260(gene)|ensembl:ENST00000331380(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q16777|rcsb pdb:6Y5E|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|refseq:NP_003508.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:Wejrpp9wK3GvA4ahJDVyEH+cwlQ9606 intact-crc:6A1177800B2002E7|rigid:TsiYMkLL4xOZEg5UMyM3MY2qdjY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q6FI13 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-353620|uniprotkb:P20670|uniprotkb:B2R5F0|ensembl:ENSP00000358155|ensembl:ENSP00000475814 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2a2a_human(display_long)|uniprotkb:H2AC18(gene name)|psi-mi:H2AC18(display_short)|uniprotkb:H2AC19(gene name)|psi-mi:H2AC19(display_short)|uniprotkb:H2A-clustered histone 18(gene name synonym)|uniprotkb:H2A-clustered histone 19(gene name synonym)|uniprotkb:H2AFO(gene name synonym)|uniprotkb:HIST2H2AA(gene name synonym)|uniprotkb:HIST2H2AA3(gene name synonym)|uniprotkb:HIST2H2AA4(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/o(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156559|imex:IM-17331-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_001035807.1|refseq:NP_003507.1|ensembl:ENSG00000203812(gene)|ensembl:ENSG00000272196(gene)|ensembl:ENST00000369159(transcript)|ensembl:ENST00000607355(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6Y5D|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|dip:DIP-33167N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:PMuIm2XMN5q4wk+wYJ94mmnCe4w9606 intact-crc:6A1177800B2002E7|rigid:TsiYMkLL4xOZEg5UMyM3MY2qdjY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q9UIG0 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-927482|uniprotkb:O95039|uniprotkb:O95247|uniprotkb:O95277|uniprotkb:B9EGK3|uniprotkb:Q6P1K4|uniprotkb:Q86UJ6|uniprotkb:D3DXE9|ensembl:ENSP00000342434|ensembl:ENSP00000385442 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:baz1b_human(display_long)|uniprotkb:BAZ1B(gene name)|psi-mi:BAZ1B(display_short)|uniprotkb:WBSC10(gene name synonym)|uniprotkb:WBSCR9(gene name synonym)|uniprotkb:WSTF(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 9 protein(gene name synonym)|uniprotkb:Williams syndrome transcription factor(gene name synonym)|uniprotkb:WBSCR10(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 10 protein(gene name synonym)|uniprotkb:Bromodomain adjacent to zinc finger domain protein 1B(gene name synonym)|uniprotkb:hWALp2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156559|imex:IM-17331-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_115784.1|refseq:XP_016868262.1|dip:DIP-35642N|ensembl:ENSG00000009954(gene)|ensembl:ENST00000339594(transcript)|ensembl:ENST00000404251(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0016604"(nuclear body)|go:"GO:0035173"(histone kinase activity)|go:"GO:0042393"(histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013136(WSTF/Acf1/Cbp146)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019786|interpro:IPR019787|interpro:IPR028941|interpro:IPR028942|interpro:IPR036427|interpro:IPR037375|mint:Q9UIG0|rcsb pdb:1F62|rcsb pdb:5NNF|reactome:R-HSA-5250924|reactome:R-HSA-5693565 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:1GTflhs9UUxTv4SPOYPKmuKAtSQ9606 intact-crc:6A1177800B2002E7|rigid:TsiYMkLL4xOZEg5UMyM3MY2qdjY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P20671 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-4407441|uniprotkb:A0PK91|uniprotkb:P57754|uniprotkb:Q6FGY6|ensembl:ENSP00000341094 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2a1d_human(display_long)|uniprotkb:H2AC7(gene name)|psi-mi:H2AC7(display_short)|uniprotkb:H2AFG(gene name synonym)|uniprotkb:HIST1H2AD(gene name synonym)|uniprotkb:Histone H2A.3(gene name synonym)|uniprotkb:Histone H2A/g(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156559|imex:IM-17331-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_066409.1|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000196866(gene)|ensembl:ENST00000341023(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:5GT3|rcsb pdb:6KBB|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:Geraq+dGw3pvAAhgzzXQnYxDOOw9606 intact-crc:6A1177800B2002E7|rigid:TsiYMkLL4xOZEg5UMyM3MY2qdjY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P22102 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-356297|ensembl:ENSP00000371236|ensembl:ENSP00000371253|ensembl:ENSP00000371261|ensembl:ENSP00000459391|ensembl:ENSP00000459532|ensembl:ENSP00000461700|uniprotkb:D3DSF3|uniprotkb:D3DSF4|uniprotkb:O14659|uniprotkb:A8KA32|uniprotkb:A8K945|uniprotkb:Q52M77 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:pur2_human(display_long)|uniprotkb:GART(gene name)|psi-mi:GART(display_short)|uniprotkb:PRGS(gene name synonym)|uniprotkb:PGFT(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156559|imex:IM-17331-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0009168"(purine ribonucleoside monophosphate biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0021549"(cerebellum development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0046084"(adenine biosynthetic process)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000115(Phosphoribosylglycinamide synthetase)|interpro:IPR001555(Phosphoribosylglycinamide formyltransferase, active site)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR004607(Phosphoribosylglycinamide formyltransferase)|interpro:IPR004733(Phosphoribosylformylglycinamidine cyclo-ligase)|interpro:IPR010918(AIR synthase related protein, C-terminal)|ensembl:ENST00000571089(transcript)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|ensembl:ENST00000573055(transcript)|ensembl:ENST00000575273(transcript)|go:"GO:0003360"(brainstem development)|go:"GO:0004637"(phosphoribosylamine-glycine ligase activity)|go:"GO:0004641"(phosphoribosylformylglycinamidine cyclo-ligase activity)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|go:"GO:0004644"(phosphoribosylglycinamide formyltransferase activity)|interpro:IPR016185(PreATP-grasp-like fold)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|interpro:IPR016188(PurM, N-terminal-like)|ensembl:ENSG00000159131(gene)|ensembl:ENSG00000262473(gene)|ensembl:ENST00000381815(transcript)|ensembl:ENST00000381831(transcript)|ensembl:ENST00000381839(transcript)|interpro:IPR020560|interpro:IPR020561|interpro:IPR020562|interpro:IPR036477|interpro:IPR036676|interpro:IPR036921|interpro:IPR037123|mint:P22102|rcsb pdb:1MEJ|rcsb pdb:1MEN|rcsb pdb:1MEO|rcsb pdb:1NJS|rcsb pdb:1RBM|rcsb pdb:1RBQ|rcsb pdb:1RBY|rcsb pdb:1RBZ|rcsb pdb:1RC0|rcsb pdb:1RC1|rcsb pdb:1ZLX|rcsb pdb:1ZLY|rcsb pdb:2QK4|rcsb pdb:2V9Y|rcsb pdb:4EW1|rcsb pdb:4EW2|rcsb pdb:4EW3|rcsb pdb:4ZYT|interpro:IPR020559|rcsb pdb:4ZYU|rcsb pdb:4ZYV|rcsb pdb:4ZYW|rcsb pdb:4ZYX|rcsb pdb:4ZYY|rcsb pdb:4ZYZ|rcsb pdb:4ZZ0|rcsb pdb:4ZZ1|rcsb pdb:4ZZ2|rcsb pdb:5J9F|rcsb pdb:7JG0|rcsb pdb:4ZZ3|refseq:NP_000810.1|refseq:NP_001129477.1|refseq:NP_001129478.1|refseq:NP_780294.1|rcsb pdb:7JG4|reactome:R-HSA-73817|rcsb pdb:7JG3|refseq:XP_011527828.1|refseq:XP_006724052.1|refseq:XP_006724053.1|refseq:XP_005260998.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:7Iy33CtBsB8LHZFDP5mZ3eRX8pU9606 intact-crc:6A1177800B2002E7|rigid:TsiYMkLL4xOZEg5UMyM3MY2qdjY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q99878 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-6147676|uniprotkb:Q5JXQ5|uniprotkb:A2RUU6|ensembl:ENSP00000328484 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2a1j_human(display_long)|uniprotkb:H2AC14(gene name)|psi-mi:H2AC14(display_short)|uniprotkb:H2AFE(gene name synonym)|uniprotkb:HIST1H2AJ(gene name synonym)|uniprotkb:Histone H2A/e(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156559|imex:IM-17331-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_066544.1|ensembl:ENSG00000276368(gene)|ensembl:ENST00000333151(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:tS29VG3PpglHaYbu0w5z7pGvYyI9606 intact-crc:6A1177800B2002E7|rigid:TsiYMkLL4xOZEg5UMyM3MY2qdjY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q6P2E9 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156559|imex:IM-17331-34 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP ensembl:ENSG00000038358(gene)|interpro:IPR036322|mint:Q6P2E9|reactome:R-HSA-430039|ensembl:ENST00000358933(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|refseq:NP_055144.3|dip:DIP-31192N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606 intact-crc:6A1177800B2002E7|rigid:TsiYMkLL4xOZEg5UMyM3MY2qdjY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P61978 intact:EBI-6149678 intact:EBI-304185|intact:EBI-28971491|ensembl:ENSP00000317788|ensembl:ENSP00000353552|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q59F98|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62|uniprotkb:Q5T6W4|intact:EBI-3440248|uniprotkb:Q6IBN1 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:hnrpk_human(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) ensembl:ENSG00000165119(gene)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000351839(transcript)|ensembl:ENST00000360384(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0002102"(podosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61978|rcsb pdb:1J5K|rcsb pdb:1KHM|rcsb pdb:1ZZI|rcsb pdb:1ZZJ|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9610379|rcsb pdb:1ZZK|refseq:NP_002131.2|refseq:NP_112552.1|refseq:NP_112553.1|ensembl:ENSP00000317788|ensembl:ENSP00000353552|ensembl:ENST00000376263|ensembl:ENSP00000365439|ensembl:ENST00000376281|ensembl:ENSP00000365458|refseq:NP_001305115.1|refseq:NP_001305116.1|refseq:NP_001305117.1|refseq:XP_016870157.1|refseq:XP_005252017.1|refseq:XP_005252020.1|refseq:XP_005252022.1|dip:DIP-31805N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P05141 intact:EBI-6149678 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P35268 intact:EBI-6149678 intact:EBI-354533|intact:EBI-1055963|uniprotkb:Q6IBD1|uniprotkb:B2R495|ensembl:ENSP00000346088 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:rl22_human(display_long)|uniprotkb:RPL22(gene name)|psi-mi:RPL22(display_short)|uniprotkb:Heparin-binding protein HBp15(gene name synonym)|uniprotkb:Epstein-Barr virus small RNA-associated protein(gene name synonym)|uniprotkb:EBER-associated protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL22(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_000974.1|ensembl:ENSG00000116251(gene)|ensembl:ENST00000234875(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008201"(heparin binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0045182"(translation regulator activity)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099577"(regulation of translation at presynapse, modulating synaptic transmission)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002671(Ribosomal protein L22e)|interpro:IPR038526|mint:P35268|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|reactome:R-HSA-72706|rcsb pdb:6Z6L|rcsb pdb:6Z6M|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:0TVillnqDkHmdTwxIedAJCVAdzY9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:Q8WWM7 intact:EBI-6149678 intact:EBI-948363|ensembl:ENSP00000338718|uniprotkb:O95135|uniprotkb:Q6NVJ8|uniprotkb:Q6PJW6|uniprotkb:Q8IU61|uniprotkb:Q8IU95|uniprotkb:Q8WWM3|uniprotkb:Q8WWM4|uniprotkb:Q8WWM5|uniprotkb:Q8WWM6|uniprotkb:Q99703|uniprotkb:B9EGM2|uniprotkb:E9PAR9|uniprotkb:A8K1R6|uniprotkb:Q63ZY4 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:atx2l_human(display_long)|uniprotkb:Ataxin-2 domain protein(gene name synonym)|uniprotkb:Ataxin-2-related protein(gene name synonym)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short)|uniprotkb:A2D(gene name synonym)|uniprotkb:A2LG(gene name synonym)|uniprotkb:A2LP(gene name synonym)|uniprotkb:A2RP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) ensembl:ENSG00000168488(gene)|ensembl:ENST00000336783(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045296"(cadherin binding)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR025852|mint:Q8WWM7|refseq:NP_009176.2|refseq:NP_663760.1|refseq:NP_680780.1|refseq:NP_680781.1|refseq:XP_005255123.1|refseq:NP_059867.3|refseq:NP_680782.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:t7lrS10IM/5pt+rrbqBRowZ6b+09606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P62258 intact:EBI-6149678 intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:Q9BUJ2 intact:EBI-6149678 intact:EBI-1018153|uniprotkb:O76022|uniprotkb:Q6ZSZ0|uniprotkb:Q7L8P4|uniprotkb:Q8N6Z4|uniprotkb:Q96G37|uniprotkb:Q9HAL3|uniprotkb:Q9UG75|intact:EBI-3183399|intact:EBI-2339292|uniprotkb:B3KMW7|ensembl:ENSP00000375863|intact:EBI-2563529 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:hnrl1_human(display_long)|uniprotkb:E1BAP5(gene name synonym)|uniprotkb:HNRNPUL1(gene name)|psi-mi:HNRNPUL1(display_short)|uniprotkb:HNRPUL1(gene name synonym)|uniprotkb:Adenovirus early region 1B-associated protein 5(gene name synonym)|uniprotkb:E1B-55 kDa-associated protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_008971.2|refseq:NP_653333.1|go:"GO:0009615"(response to virus)|go:"GO:0019899"(enzyme binding)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027025|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q9BUJ2|reactome:R-HSA-72163|ensembl:ENSG00000105323(gene)|ensembl:ENST00000392006(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|refseq:NP_001308140.1|refseq:NP_001308137.1|dip:DIP-39419N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:IahA7SVR1NmvldrWKQlAwApinQE9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:Q10570 intact:EBI-6149678 intact:EBI-347859|ensembl:ENSP00000478145|ensembl:ENSP00000484669|ensembl:ENSP00000495020|ensembl:ENSP00000495102|uniprotkb:Q96AF0 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:cpsf1_human(display_long)|uniprotkb:CPSF1(gene name)|psi-mi:CPSF1(display_short)|uniprotkb:CPSF160(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 160 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) rcsb pdb:6F9N|rcsb pdb:6FBS|rcsb pdb:6FUW|rcsb pdb:6URG|rcsb pdb:6URO|reactome:R-HSA-159231|reactome:R-HSA-6784531|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:6DNH|reactome:R-HSA-77595|ensembl:ENSG00000071894(gene)|ensembl:ENSG00000285049(gene)|ensembl:ENST00000616140(transcript)|ensembl:ENST00000620219(transcript)|ensembl:ENST00000643746(transcript)|ensembl:ENST00000644539(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|mint:Q10570|rcsb pdb:6BLY|rcsb pdb:6BM0|refseq:NP_037423.2|dip:DIP-32694N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:YZdY/qkUWUDbe+Dw3g9bY9DFbig9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:O43390 intact:EBI-6149678 intact:EBI-713419|uniprotkb:S4R3J4|uniprotkb:Q5TEH1|ensembl:ENSP00000304405|ensembl:ENSP00000363741|ensembl:ENSP00000489252|ensembl:ENSP00000489371|uniprotkb:Q9BV64|uniprotkb:Q2L7G6 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:hnrpr_human(display_long)|uniprotkb:HNRPR(gene name synonym)|uniprotkb:HNRNPR(gene name)|psi-mi:HNRNPR(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_001095868.1|refseq:XP_005245768.1|ensembl:ENSG00000125944(gene)|ensembl:ENSG00000282958(gene)|ensembl:ENST00000302271(transcript)|ensembl:ENST00000374612(transcript)|ensembl:ENST00000634263(transcript)|ensembl:ENST00000634766(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043679"(axon terminus)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034411|interpro:IPR035979|mint:O43390|rcsb pdb:2DK2|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR041337|refseq:NP_005817.1|refseq:XP_011538773.1|refseq:NP_001284549.1|refseq:XP_016855497.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:UiOaRbnMd1S2FthR4RWltyq6xT49606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:Q93077 intact:EBI-6149678 intact:EBI-725259|uniprotkb:O00775|uniprotkb:O00776|uniprotkb:O00777|uniprotkb:O00778|uniprotkb:Q540R1|uniprotkb:B2R4F7|ensembl:ENSP00000321389|ensembl:ENSP00000367022|ensembl:ENSP00000473534 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:h2a1c_human(display_long)|uniprotkb:H2AC6(gene name)|psi-mi:H2AC6(display_short)|uniprotkb:H2A-clustered histone 6(gene name synonym)|uniprotkb:H2AFL(gene name synonym)|uniprotkb:HIST1H2AC(gene name synonym)|uniprotkb:Histone H2A/l(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_003503.1|ensembl:ENSG00000180573(gene)|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENST00000314088(transcript)|ensembl:ENST00000377791(transcript)|ensembl:ENST00000602637(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|rcsb pdb:6C0W|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:7A08|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|interpro:IPR032458 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:m00IdooZksbNGKHSsaVvGFVpcko9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P42336 intact:EBI-6149678 intact:EBI-2116585|uniprotkb:Q14CW1|uniprotkb:Q99762|ensembl:ENSP00000263967 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:pk3ca_human(display_long)|uniprotkb:Phosphoinositide-3-kinase catalytic alpha polypeptide(gene name synonym)|uniprotkb:Serine/threonine protein kinase PIK3CA(gene name synonym)|uniprotkb:PIK3CA(gene name)|psi-mi:PIK3CA(display_short)|uniprotkb:Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha(gene name synonym)|uniprotkb:Phosphoinositide 3-kinase alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:XP_011511196.1|refseq:XP_006713721.1|refseq:NP_006209.2|dip:DIP-42728N|ensembl:ENSG00000121879(gene)|ensembl:ENST00000263967(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001944"(vasculature development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0005944"(phosphatidylinositol 3-kinase complex, class IB)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006909"(phagocytosis)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030168"(platelet activation)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035004"(phosphatidylinositol 3-kinase activity)|go:"GO:0035005"(1-phosphatidylinositol-4-phosphate 3-kinase activity)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0038028"(insulin receptor signaling pathway via phosphatidylinositol 3-kinase)|go:"GO:0038084"(vascular endothelial growth factor signaling pathway)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0043276"(anoikis)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044029"(hypomethylation of CpG island)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046934"(phosphatidylinositol-4,5-bisphosphate 3-kinase activity)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110053"(regulation of actin filament organization)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR000341(Phosphoinositide 3-kinase, ras-binding)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR003113(Phosphatidylinositol 3-kinase, p85-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR029071|interpro:IPR035892|interpro:IPR036940|interpro:IPR037704|interpro:IPR042236|mint:P42336|rcsb pdb:2ENQ|rcsb pdb:2RD0|rcsb pdb:3HHM|rcsb pdb:3HIZ|rcsb pdb:3ZIM|rcsb pdb:4JPS|rcsb pdb:4L1B|rcsb pdb:4L23|rcsb pdb:4L2Y|rcsb pdb:4OVU|rcsb pdb:4OVV|rcsb pdb:4TUU|rcsb pdb:4TV3|rcsb pdb:4WAF|rcsb pdb:4YKN|rcsb pdb:4ZOP|rcsb pdb:5DXT|rcsb pdb:5FI4|rcsb pdb:5ITD|rcsb pdb:5SW8|rcsb pdb:5SWG|rcsb pdb:5SWO|rcsb pdb:5SWP|rcsb pdb:5SWR|rcsb pdb:5SWT|rcsb pdb:5SX8|rcsb pdb:5SX9|rcsb pdb:5SXA|rcsb pdb:5SXB|rcsb pdb:5SXC|rcsb pdb:5SXD|rcsb pdb:5SXE|rcsb pdb:5SXF|rcsb pdb:5SXI|rcsb pdb:5SXJ|rcsb pdb:5SXK|rcsb pdb:5UBR|rcsb pdb:5UK8|rcsb pdb:5UKJ|rcsb pdb:5UL1|rcsb pdb:5XGH|rcsb pdb:5XGI|rcsb pdb:5XGJ|rcsb pdb:6GVF|rcsb pdb:6GVG|rcsb pdb:6GVH|rcsb pdb:6GVI|rcsb pdb:6NCT|rcsb pdb:6OAC|rcsb pdb:6PYS|rcsb pdb:6VO7|rcsb pdb:7JIU|rcsb pdb:7K6M|rcsb pdb:7K6N|rcsb pdb:7K6O|rcsb pdb:7K71|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1236382|reactome:R-HSA-1250342|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-180292|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-1963642|reactome:R-HSA-198203|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654689|reactome:R-HSA-5654695|reactome:R-HSA-5654710|reactome:R-HSA-5654720|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-9009391|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9027276|reactome:R-HSA-9028335|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9603381|reactome:R-HSA-9607240|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|rcsb pdb:5DXH|reactome:R-HSA-9703465|reactome:R-HSA-9703648 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:YIZWt9VfCmyBCWYkqAEaMAEsl3w9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:Q9H0C2 intact:EBI-6149678 intact:EBI-6149672|ensembl:ENSP00000281154 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:adt4_human(display_long)|uniprotkb:SLC25A31(gene name)|psi-mi:SLC25A31(display_short)|uniprotkb:AAC4(gene name synonym)|uniprotkb:ADP,ATP carrier protein 4(gene name synonym)|uniprotkb:ANT4(gene name synonym)|uniprotkb:Adenine nucleotide translocator 4(gene name synonym)|uniprotkb:SFEC(gene name synonym)|uniprotkb:Solute carrier family 25 member 31(gene name synonym)|uniprotkb:Sperm flagellar energy carrier protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_001305396.1|refseq:NP_112581.1|ensembl:ENSG00000151475(gene)|ensembl:ENST00000281154(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031514"(motile cilium)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:41l4B5IjJBVvzEcuNsV2T931oWs9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P27348 intact:EBI-6149678 intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081|ensembl:ENSP00000371267 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_006817.1|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|ensembl:ENSG00000134308(gene)|ensembl:ENST00000238081(transcript)|ensembl:ENST00000381844(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|dip:DIP-27584N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:Q7L2E3 intact:EBI-6149678 intact:EBI-1211456|uniprotkb:O94965|uniprotkb:Q7Z753|uniprotkb:Q96CH4|uniprotkb:Q9NUQ0|uniprotkb:A8K5F1|ensembl:ENSP00000392601|ensembl:ENSP00000405620|intact:EBI-21350949 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:dhx30_human(display_long)|uniprotkb:DHX30(gene name)|psi-mi:DHX30(display_short)|uniprotkb:KIAA0890(gene name synonym)|uniprotkb:DDX30(gene name synonym)|uniprotkb:DEAH box protein 30(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_055781.2|refseq:NP_619520.1|refseq:XP_011531796.1|refseq:XP_011531797.1|refseq:XP_016861406.1|ensembl:ENSG00000132153(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007417"(central nervous system development)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902775"(mitochondrial large ribosomal subunit assembly)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|mint:Q7L2E3|rcsb pdb:2DB2|ensembl:ENST00000445061(transcript)|ensembl:ENST00000446256(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:tb4GzZKLycraXS0NlVqj8reV3IQ9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P31942 intact:EBI-6149678 intact:EBI-711437|uniprotkb:Q9NPI4|uniprotkb:Q9UFU4|uniprotkb:Q9Y4J5|uniprotkb:Q9BSX1|uniprotkb:Q9NP53|uniprotkb:Q9NP96|uniprotkb:Q9NPA7|ensembl:ENSP00000265866|uniprotkb:A8K682|uniprotkb:B3KRE1 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:hnrh3_human(display_long)|uniprotkb:HNRNPH3(gene name)|psi-mi:HNRNPH3(display_short)|uniprotkb:HNRPH3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein 2H9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) ensembl:ENSG00000096746(gene)|ensembl:ENST00000265866(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034969|interpro:IPR034970|interpro:IPR035979|mint:P31942|refseq:NP_036339.1|refseq:NP_067676.2|refseq:NP_001309363.1|refseq:NP_001309365.1|refseq:NP_001309366.1|refseq:NP_001309367.1|refseq:NP_001309368.1|refseq:NP_001309369.1|refseq:NP_001309370.1|refseq:NP_001309374.1|refseq:NP_001309375.1|refseq:NP_001309376.1|refseq:NP_001309377.1|refseq:NP_001309378.1|refseq:XP_016871657.1|refseq:XP_016871658.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:iJGBIhPXnQIIFQmgxWB1WjwVXSY9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:Q16777 intact:EBI-6149678 intact:EBI-5325566|ensembl:ENSP00000332194|uniprotkb:Q6DRA7|uniprotkb:Q8IUE5 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:h2a2c_human(display_long)|uniprotkb:H2AC20(gene name)|psi-mi:H2AC20(display_short)|uniprotkb:H2A-clustered histone 20(gene name synonym)|uniprotkb:H2AFQ(gene name synonym)|uniprotkb:HIST2H2AC(gene name synonym)|uniprotkb:Histone H2A-GL101(gene name synonym)|uniprotkb:Histone H2A/q(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-5689603|ensembl:ENSG00000184260(gene)|ensembl:ENST00000331380(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q16777|rcsb pdb:6Y5E|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|refseq:NP_003508.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:Wejrpp9wK3GvA4ahJDVyEH+cwlQ9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:Q6FI13 intact:EBI-6149678 intact:EBI-353620|uniprotkb:P20670|uniprotkb:B2R5F0|ensembl:ENSP00000358155|ensembl:ENSP00000475814 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:h2a2a_human(display_long)|uniprotkb:H2AC18(gene name)|psi-mi:H2AC18(display_short)|uniprotkb:H2AC19(gene name)|psi-mi:H2AC19(display_short)|uniprotkb:H2A-clustered histone 18(gene name synonym)|uniprotkb:H2A-clustered histone 19(gene name synonym)|uniprotkb:H2AFO(gene name synonym)|uniprotkb:HIST2H2AA(gene name synonym)|uniprotkb:HIST2H2AA3(gene name synonym)|uniprotkb:HIST2H2AA4(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/o(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_001035807.1|refseq:NP_003507.1|ensembl:ENSG00000203812(gene)|ensembl:ENSG00000272196(gene)|ensembl:ENST00000369159(transcript)|ensembl:ENST00000607355(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6Y5D|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|dip:DIP-33167N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:PMuIm2XMN5q4wk+wYJ94mmnCe4w9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P67809 intact:EBI-6149678 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:Q99729 intact:EBI-6149678 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:Q86U42 intact:EBI-6149678 intact:EBI-1226435|uniprotkb:O43484|uniprotkb:D3DS49|ensembl:ENSP00000216727 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:pabp2_human(display_long)|uniprotkb:PABPN1(gene name)|psi-mi:PABPN1(display_short)|uniprotkb:PAB2(gene name synonym)|uniprotkb:PABP2(gene name synonym)|uniprotkb:"Poly(A)-binding protein II"(gene name synonym)|uniprotkb:Polyadenylate-binding nuclear protein 1(gene name synonym)|uniprotkb:"Nuclear poly(A)-binding protein 1"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_004634.1|dip:DIP-37968N|go:"GO:0000165"(MAPK cascade)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|ensembl:ENSG00000100836(gene)|ensembl:ENST00000216727(transcript)|go:"GO:0006936"(muscle contraction)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1904247"(positive regulation of polynucleotide adenylyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034911|interpro:IPR035979|mint:Q86U42|rcsb pdb:3B4D|rcsb pdb:3B4M|rcsb pdb:3UCG|reactome:R-HSA-168315|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0070063"(RNA polymerase binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:NxWuFTvVqshfu+ZIsZMIZEdSk2k9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P63267 intact:EBI-6149678 intact:EBI-297795|uniprotkb:P12718|uniprotkb:Q504R1|uniprotkb:Q6FI22|ensembl:ENSP00000295137|ensembl:ENSP00000386857|uniprotkb:B2R7E7|uniprotkb:D6W5H8|uniprotkb:B4E315|uniprotkb:E9PG30 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:acth_human(display_long)|uniprotkb:ACTG2(gene name)|psi-mi:ACTG2(display_short)|uniprotkb:ACTA3(gene name synonym)|uniprotkb:ACTSG(gene name synonym)|uniprotkb:Smooth muscle gamma-actin(gene name synonym)|uniprotkb:Gamma-2-actin(gene name synonym)|uniprotkb:Alpha-actin-3(gene name synonym)|uniprotkb:ACTL3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0032982"(myosin filament)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:6JAT|reactome:R-HSA-445355|go:"GO:0010628"(positive regulation of gene expression)|ensembl:ENST00000345517(transcript)|ensembl:ENST00000409624(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|ensembl:ENSG00000163017(gene)|refseq:NP_001186822.1|refseq:NP_001606.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:tp0JsXhrGsRl5i4Wg2dyaPGUPxA9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P12236 intact:EBI-6149678 intact:EBI-356254|ensembl:ENSP00000370808|uniprotkb:Q96C49 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) ensembl:ENSG00000169100(gene)|ensembl:ENST00000381401(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|refseq:NP_001627.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P11940 intact:EBI-6149678 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P43243 intact:EBI-6149678 intact:EBI-352602|ensembl:ENSP00000378284|ensembl:ENSP00000482895|uniprotkb:Q9UHW0|uniprotkb:Q9UQ27|uniprotkb:D3DQC3|uniprotkb:B7ZAV5 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:matr3_human(display_long)|uniprotkb:KIAA0723(gene name synonym)|uniprotkb:MATR3(gene name)|psi-mi:MATR3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) ensembl:ENSG00000015479(gene)|ensembl:ENST00000394805(transcript)|ensembl:ENST00000618441(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:P43243|refseq:NP_001181883.1|refseq:NP_001181884.1|refseq:NP_061322.2|refseq:NP_954659.1|refseq:NP_001181885.1|refseq:NP_001269207.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:3UZlyCZHgdr1SBgUctv9Ev7XBSQ9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:Q7L7L0 intact:EBI-6149678 intact:EBI-5325551|ensembl:ENSP00000355656|ensembl:ENSP00000493926|uniprotkb:B2R4S4 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:h2a3_human(display_long)|uniprotkb:H2AW(gene name)|psi-mi:H2AW(display_short)|uniprotkb:HIST3H2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) ensembl:ENSG00000181218(gene)|ensembl:ENSG00000284841(gene)|ensembl:ENST00000366695(transcript)|refseq:NP_254280.1|ensembl:ENST00000645741(transcript)|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-5689603|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q7L7L0|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000786"(nucleosome)|dip:DIP-48936N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:t0RdR1SmUtmwRjtCS3uTyLGqSUI9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:O00459 intact:EBI-6149678 intact:EBI-346930|uniprotkb:Q5EAT5|uniprotkb:Q9UPH9|intact:EBI-28974273|ensembl:ENSP00000222254 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:p85b_human(display_long)|uniprotkb:PIK3R2(gene name)|psi-mi:PIK3R2(display_short)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) ensembl:ENSP00000222254|refseq:NP_005018.1|dip:DIP-31811N|ensembl:ENSG00000105647(gene)|ensembl:ENST00000222254(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|rcsb pdb:6OX7|rcsb pdb:6U28|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-186763|reactome:R-HSA-198203|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|mint:O00459|rcsb pdb:2KT1|rcsb pdb:2XS6|rcsb pdb:3MTT|rcsb pdb:3O5Z|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-210993|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9013409 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:Ij0WS0eKPwShgFWQc7OEss7AcAU9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P07910 intact:EBI-6149678 intact:EBI-357966|uniprotkb:P22628|uniprotkb:Q53EX2|uniprotkb:Q59FD3|uniprotkb:Q5FWE8|uniprotkb:Q86SF8|uniprotkb:Q86U45|uniprotkb:Q96HK7|uniprotkb:Q96HM4|uniprotkb:Q96IY5|uniprotkb:Q9BTS3|uniprotkb:D3DS19|uniprotkb:D3DS22|intact:EBI-28976506|ensembl:ENSP00000404848|ensembl:ENSP00000451291|ensembl:ENSP00000452276 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:hnrpc_human(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_001070910.1|refseq:NP_001070911.1|refseq:NP_004491.2|refseq:NP_112604.2|ensembl:ENSP00000404848|ensembl:ENST00000430246|ensembl:ENSP00000442816|ensembl:ENST00000553300|ensembl:ENSP00000450544|ensembl:ENSP00000451291|ensembl:ENST00000554969|ensembl:ENSP00000452276|ensembl:ENSP00000450725|ensembl:ENST00000555883|ensembl:ENSP00000450629|ensembl:ENST00000556628|ensembl:ENSP00000451652|ensembl:ENST00000556897|ensembl:ENSP00000451176|refseq:XP_011535010.1|refseq:XP_011535011.1|refseq:XP_011535012.1|refseq:XP_011535013.1|refseq:XP_011535014.1|refseq:XP_016876741.1|refseq:XP_016876742.1|dip:DIP-29854N|refseq:XP_006720188.1|ensembl:ENSG00000092199(gene)|ensembl:ENST00000420743(transcript)|ensembl:ENST00000554455(transcript)|ensembl:ENST00000557201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979|mint:P07910|rcsb pdb:1TXP|rcsb pdb:1WF2|rcsb pdb:2MXY|rcsb pdb:2MZ1|rcsb pdb:3LN4|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:Fj5tiH0wrNUjTnsURIg8dB8laMg9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P62829 intact:EBI-6149678 intact:EBI-353303|uniprotkb:P23131|uniprotkb:Q3SWV7|uniprotkb:P24048|uniprotkb:Q29246|uniprotkb:Q6P5S1|ensembl:ENSP00000377865|ensembl:ENSP00000420311 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:rl23_human(display_long)|uniprotkb:RPL23(gene name)|psi-mi:RPL23(display_short)|uniprotkb:60S ribosomal protein L17(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|reactome:R-HSA-9010553|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|refseq:NP_000969.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000218(Ribosomal protein L14b/L23e)|interpro:IPR019972|interpro:IPR036853|mint:P62829|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|ensembl:ENSG00000125691(gene)|ensembl:ENST00000394332(transcript)|ensembl:ENST00000479035(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0005730"(nucleolus)|dip:DIP-33156N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:TiSVU2W4+lkwf12eb4+vG6IFlZA9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:Q9NPA8 intact:EBI-6149678 intact:EBI-719226|uniprotkb:B2RE52|intact:EBI-10972054|uniprotkb:G3V117|ensembl:ENSP00000429986 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:eny2_human(display_long)|uniprotkb:Enhancer of yellow 2 transcription factor homolog(gene name synonym)|uniprotkb:DC6(orf name)|uniprotkb:ENY2(gene name)|psi-mi:ENY2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_001180486.1|refseq:NP_064574.1|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071819"(DUBm complex)|interpro:IPR018783|interpro:IPR038212|mint:Q9NPA8|rcsb pdb:4DHX|go:"GO:0030374"(nuclear receptor coactivator activity)|reactome:R-HSA-3214847|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0015031"(protein transport)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|ensembl:ENSG00000120533(gene)|ensembl:ENST00000521688(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:CJmjqxLqgpxrqtvVVFcgxW5nloE9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P14866 intact:EBI-6149678 intact:EBI-719024|uniprotkb:Q9H3P3|uniprotkb:A6ND69|uniprotkb:A6NIT8|ensembl:ENSP00000221419|ensembl:ENSP00000489021 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:hnrpl_human(display_long)|uniprotkb:HNRPL(gene name synonym)|uniprotkb:HNRNPL(gene name)|psi-mi:HNRNPL(display_short)|uniprotkb:P/OKcl.14(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_001005335.1|refseq:NP_001524.2|refseq:XP_011525191.1|ensembl:ENSG00000282947(gene)|ensembl:ENST00000221419(transcript)|ensembl:ENST00000634753(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097157"(pre-mRNA intronic binding)|ensembl:ENSG00000104824(gene)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034816|interpro:IPR034817|interpro:IPR035005|interpro:IPR035008|interpro:IPR035979|mint:P14866|rcsb pdb:3R27|rcsb pdb:3TO8|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:1990904"(ribonucleoprotein complex)|dip:DIP-36355N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:vOfznm03e6Ottg6BptYHmR9qJEc9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:Q12905 intact:EBI-6149678 intact:EBI-357925|uniprotkb:A6NDB0|uniprotkb:Q5SR10|uniprotkb:Q5SR11|uniprotkb:Q7L7R3|uniprotkb:Q9BWD4|uniprotkb:Q9P1N0|uniprotkb:B2R8G7|ensembl:ENSP00000355011 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:ilf2_human(display_long)|uniprotkb:PRO3063(orf name)|uniprotkb:NF45(gene name synonym)|uniprotkb:ILF2(gene name)|psi-mi:ILF2(display_short)|uniprotkb:Nuclear factor of activated T-cells 45 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_004506.2|refseq:NP_001254738.1|ensembl:ENSG00000143621(gene)|ensembl:ENST00000361891(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR043519|mint:Q12905|reactome:R-HSA-6798695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:HwUDuY6Ev7csoTThxZCW8nJT88o9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:Q96KK5 intact:EBI-6149678 intact:EBI-6147668|ensembl:ENSP00000366679 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:h2a1h_human(display_long)|uniprotkb:H2AC12(gene name)|psi-mi:H2AC12(display_short)|uniprotkb:H2A-clustered histone 12(gene name synonym)|uniprotkb:HIST1H2AH(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:Histone H2A/s(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_542163.1|dip:DIP-61699N|ensembl:ENSG00000274997(gene)|ensembl:ENST00000377459(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:Oa322n+evy8Cu0E9cWTEdYwQPKM9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:O60506 intact:EBI-6149678 intact:EBI-1024357|uniprotkb:Q53H05|uniprotkb:Q5TCG2|uniprotkb:Q8IW78|uniprotkb:Q8N599|uniprotkb:Q96LC1|uniprotkb:Q96LC2|uniprotkb:Q9Y583|uniprotkb:Q5TCG3|uniprotkb:E1P501|uniprotkb:E1P502|ensembl:ENSP00000358635|ensembl:ENSP00000503783|ensembl:ENSP00000504706 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:hnrpq_human(display_long)|uniprotkb:Synaptotagmin-binding, cytoplasmic RNA-interacting protein(gene name synonym)|uniprotkb:Glycine- and tyrosine-rich RNA-binding protein(gene name synonym)|uniprotkb:NS1-associated protein 1(gene name synonym)|uniprotkb:SYNCRIP(gene name)|psi-mi:SYNCRIP(display_short)|uniprotkb:HNRPQ(gene name synonym)|uniprotkb:NSAP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_001153145.1|refseq:NP_001153146.1|refseq:NP_001153147.1|refseq:NP_001240700.1|refseq:NP_001153148.1|refseq:NP_001153149.1|refseq:NP_006363.4|ensembl:ENSG00000135316(gene)|ensembl:ENST00000369622(transcript)|ensembl:ENST00000676688(transcript)|ensembl:ENST00000678355(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034544|interpro:IPR034548|interpro:IPR035979|interpro:IPR041337|mint:O60506|rcsb pdb:2DGU|rcsb pdb:2MXT|rcsb pdb:2NBB|rcsb pdb:6KOR|refseq:XP_016865667.1|refseq:XP_005248694.1|dip:DIP-35540N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:2rDkXIp/wWzTOoVtN7Bd3uqZo689606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:Q9NNW5 intact:EBI-6149678 intact:EBI-1568315|uniprotkb:B4DHK2|uniprotkb:Q3MIT1|uniprotkb:Q9UF63|ensembl:ENSP00000477389 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:wdr6_human(display_long)|uniprotkb:WDR6(gene name)|psi-mi:WDR6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_060501.3|refseq:NP_001307475.1|refseq:NP_001307476.1|ensembl:ENSG00000178252(gene)|ensembl:ENST00000608424(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0030488"(tRNA methylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9NNW5|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:gYSDkyuDdKhj387/1P3bhpKJXy89606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P62805 intact:EBI-6149678 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:Q12906 intact:EBI-6149678 intact:EBI-78756|uniprotkb:A8K6F2|uniprotkb:O43409|uniprotkb:Q6P1X1|uniprotkb:Q86XY7|uniprotkb:Q99544|uniprotkb:Q99545|uniprotkb:Q9BZH4|uniprotkb:Q9BZH5|uniprotkb:Q9NQ95|uniprotkb:Q9NQ96|uniprotkb:Q9NQ97|uniprotkb:Q9NQ98|uniprotkb:Q9NQ99|uniprotkb:Q9NQA0|uniprotkb:Q9NQA1|uniprotkb:Q9NQA2|uniprotkb:Q9NRN2|uniprotkb:Q9NRN3|uniprotkb:Q9NRN4|uniprotkb:Q9UMZ9|uniprotkb:Q9UN00|uniprotkb:Q9UN84|uniprotkb:Q9UNA2|ensembl:ENSP00000468156|intact:EBI-10970055|uniprotkb:G5E9M5 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:ilf3_human(display_long)|uniprotkb:ILF3(gene name)|psi-mi:ILF3(display_short)|uniprotkb:MPHOSPH4(gene name synonym)|uniprotkb:NF90(gene name synonym)|uniprotkb:Nuclear factor of activated T-cells 90 kDa(gene name synonym)|uniprotkb:Double-stranded RNA-binding protein 76(gene name synonym)|uniprotkb:Translational control protein 80(gene name synonym)|uniprotkb:Nuclear factor associated with dsRNA(gene name synonym)|uniprotkb:M-phase phosphoprotein 4(gene name synonym)|uniprotkb:DRBF(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) ensembl:ENSG00000129351(gene)|ensembl:ENST00000590261(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051607"(defense response to virus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR033099|interpro:IPR043519|mint:Q12906|rcsb pdb:2L33|rcsb pdb:3P1X|refseq:NP_001131145.1|refseq:NP_004507.2|refseq:NP_036350.2|refseq:NP_060090.2|refseq:NP_703194.1|refseq:XP_016882252.1|refseq:XP_011526286.2|dip:DIP-29853N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:iri+WBUtektANRSCpBO1XBCd9Wk9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:Q5JVF3 intact:EBI-6149678 intact:EBI-1051701|uniprotkb:A6NK09|uniprotkb:Q3ZCX1|uniprotkb:Q5TC57|uniprotkb:Q5TC58|uniprotkb:Q9H7K1|uniprotkb:Q9HBZ7|uniprotkb:Q9NUK6|uniprotkb:Q9NVY1|uniprotkb:Q9NW44|uniprotkb:Q9NWH3|ensembl:ENSP00000337405|ensembl:ENSP00000364626|ensembl:ENSP00000364628 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:pcid2_human(display_long)|uniprotkb:CSN12-like protein(gene name synonym)|uniprotkb:PCID2(gene name)|psi-mi:PCID2(display_short)|uniprotkb:HT004(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_001120674.1|refseq:NP_001120675.1|refseq:NP_060856.2|refseq:NP_001245142.1|refseq:NP_001307584.1|refseq:NP_001307585.1|refseq:NP_001307586.1|refseq:NP_001307589.1|ensembl:ENSG00000126226(gene)|ensembl:ENST00000337344(transcript)|ensembl:ENST00000375477(transcript)|ensembl:ENST00000375479(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048536"(spleen development)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:2000117"(negative regulation of cysteine-type endopeptidase activity)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|rcsb pdb:3T5X|refseq:XP_016876153.1|dip:DIP-50497N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:jFHv4Xifu2Qw/CzD5SKl3PgJpgE9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P04908 intact:EBI-6149678 intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:4Qno1mMYZB6FdNoojrzulWLVq849606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:Q8N163 intact:EBI-6149678 intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|ensembl:ENSP00000310670|ensembl:ENSP00000373930|uniprotkb:B2RB79|uniprotkb:D3DSR6 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_066997.3|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|interpro:IPR028811|mint:Q8N163|reactome:R-HSA-3371453|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|dip:DIP-38122N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:Q9BTM1 intact:EBI-6149678 intact:EBI-4398590|uniprotkb:Q9NV63|ensembl:ENSP00000373730|ensembl:ENSP00000438553 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:h2aj_human(display_long)|uniprotkb:H2AJ(gene name)|psi-mi:H2AJ(display_short)|uniprotkb:H2AFJ(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_808760.1|ensembl:ENSG00000246705(gene)|ensembl:ENST00000389078(transcript)|ensembl:ENST00000544848(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:4EDU|rcsb pdb:6K60|rcsb pdb:6KVD|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-8939236 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:g6br63FeM17yJRfQI3GnmoM0vbc9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:Q5VTE0 intact:EBI-6149678 intact:EBI-877809 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:ef1a3_human(display_long)|uniprotkb:EEF1A1P5(gene name)|psi-mi:EEF1A1P5(display_short)|uniprotkb:Eukaryotic elongation factor 1 A-like 3(gene name synonym)|uniprotkb:EEF1AL3(gene name synonym)|uniprotkb:Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR031157|reactome:R-HSA-156842|interpro:IPR027417 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:3t6tj3i+3CKTC1NsrHyBkeoRK789606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P0C0S8 intact:EBI-6149678 intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:O43143 intact:EBI-6149678 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P22626 intact:EBI-6149678 intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P63104 intact:EBI-6149678 intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:Q00839 intact:EBI-6149678 intact:EBI-351126|uniprotkb:O75507|uniprotkb:Q8N174|uniprotkb:Q96HY9|uniprotkb:Q9BQ09|ensembl:ENSP00000491215 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:hnrpu_human(display_long)|uniprotkb:HNRNPU(gene name)|psi-mi:HNRNPU(display_short)|uniprotkb:SAFA(gene name synonym)|uniprotkb:U21.1(gene name synonym)|uniprotkb:HNRPU(gene name synonym)|uniprotkb:p120(gene name synonym)|uniprotkb:pp120(gene name synonym)|uniprotkb:C1orf199(gene name synonym)|uniprotkb:GRIP120(gene name synonym)|uniprotkb:Nuclear p120 ribonucleoprotein(gene name synonym)|uniprotkb:Scaffold-attachment factor A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_004492.2|refseq:NP_114032.2|ensembl:ENSG00000153187(gene)|ensembl:ENST00000640218(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:1990498"(mitotic spindle microtubule)|go:"GO:0098577"(inactive sex chromosome)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR026745|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q00839|rcsb pdb:1ZRJ|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990280"(RNA localization to chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006396"(RNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008143"("poly(A) binding")|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0017130"("poly(C) RNA binding")|go:"GO:0030496"(midbody)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|refseq:XP_016856604.1|refseq:XP_016856605.1|refseq:XP_016856606.1|dip:DIP-684N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:n73PY0Vis+D5Iq0q77h5Ck2V4789606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P23396 intact:EBI-6149678 intact:EBI-351193|uniprotkb:Q498B5|uniprotkb:Q8NI95|uniprotkb:B2R7N5|ensembl:ENSP00000433821|ensembl:ENSP00000434643|ensembl:ENSP00000436971|uniprotkb:J3KN86 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:rs3_human(display_long)|uniprotkb:RPS3(gene name)|psi-mi:RPS3(display_short)|uniprotkb:Small ribosomal subunit protein uS3(gene name synonym)|uniprotkb:OK/SW-cl.26(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_000996.2|ensembl:ENSG00000149273(gene)|ensembl:ENST00000524851(transcript)|ensembl:ENST00000527446(transcript)|ensembl:ENST00000531188(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR004044(K Homology, type 2)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|go:"GO:0071159"(NF-kappaB complex)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR018280|interpro:IPR036419|mint:P23396|rcsb pdb:1WH9|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|rcsb pdb:6QZP|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|refseq:NP_001243731.1|refseq:NP_001247436.1|refseq:NP_001247435.1|dip:DIP-33177N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:fsDW18AMR3YyEEIhMVcngYRWkps9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:O14654 intact:EBI-6149678 intact:EBI-356594|ensembl:ENSP00000505547 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P09651 intact:EBI-6149678 intact:EBI-352662|uniprotkb:Q3MIB7|uniprotkb:Q6PJZ7|ensembl:ENSP00000341826|ensembl:ENSP00000503610|uniprotkb:A8K4Z8|intact:EBI-2556572 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:roa1_human(display_long)|uniprotkb:HNRNPA1(gene name)|psi-mi:HNRNPA1(display_short)|uniprotkb:HNRPA1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:Single-strand RNA-binding protein(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_002127.1|refseq:NP_112420.1|ensembl:ENSG00000135486(gene)|ensembl:ENST00000340913(transcript)|ensembl:ENST00000677210(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|rcsb pdb:2LYV|rcsb pdb:2UP1|rcsb pdb:4YOE|rcsb pdb:5MPG|rcsb pdb:5MPL|rcsb pdb:5ZGD|rcsb pdb:5ZGL|rcsb pdb:6BXX|rcsb pdb:6DCL|rcsb pdb:6J60|rcsb pdb:7BX7|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035198"(miRNA binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051170"(import into nucleus)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR034845|interpro:IPR035979|mint:P09651|rcsb pdb:1HA1|rcsb pdb:1L3K|rcsb pdb:1PGZ|rcsb pdb:1PO6|rcsb pdb:1U1K|rcsb pdb:1U1L|rcsb pdb:1U1M|rcsb pdb:1U1N|rcsb pdb:1U1O|rcsb pdb:1U1P|rcsb pdb:1U1Q|rcsb pdb:1U1R|rcsb pdb:1UP1|rcsb pdb:2H4M|refseq:XP_005268883.1|dip:DIP-29338N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:ECXjsLRVtNc/aOw90tEFxowHc6c9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:Q08211 intact:EBI-6149678 intact:EBI-352022|intact:EBI-1058470|uniprotkb:Q5VY62|uniprotkb:Q6PD69|uniprotkb:Q99556|uniprotkb:B2RNV4|uniprotkb:Q05CI5|uniprotkb:Q12803|uniprotkb:Q32Q22|ensembl:ENSP00000356520 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:dhx9_human(display_long)|uniprotkb:DHX9(gene name)|psi-mi:DHX9(display_short)|uniprotkb:DDX9(gene name synonym)|uniprotkb:NDH2(gene name synonym)|uniprotkb:DExH-box helicase 9(gene name synonym)|uniprotkb:RNA helicase A(gene name synonym)|uniprotkb:LKP(gene name synonym)|uniprotkb:Nuclear DNA helicase II(gene name synonym)|uniprotkb:DEAH box protein 9(gene name synonym)|uniprotkb:Leukophysin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_001348.2|dip:DIP-31504N|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033679"(3'-5' DNA/RNA helicase activity)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045142"(triplex DNA binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0097165"(nuclear stress granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1905172"(RISC complex binding)|go:"GO:1905538"(polysome binding)|go:"GO:1905698"(positive regulation of polysome binding)|go:"GO:1990518"(single-stranded 3'-5' DNA helicase activity)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000765"(regulation of cytoplasmic translation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR044445|interpro:IPR044446|interpro:IPR044447|mint:Q08211|rcsb pdb:3LLM|rcsb pdb:3VYX|rcsb pdb:3VYY|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-72163|go:"GO:1904973"(positive regulation of viral translation)|ensembl:ENSG00000135829(gene)|ensembl:ENST00000367549(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006260"(DNA replication)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0016604"(nuclear body) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:b0VP2Frtvwa9WbYVMwB6TbV2uGU9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P12235 intact:EBI-6149678 intact:EBI-359074|uniprotkb:D3DP59|ensembl:ENSP00000281456 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:adt1_human(display_long)|uniprotkb:SLC25A4(gene name)|psi-mi:SLC25A4(display_short)|uniprotkb:ANT1(gene name synonym)|uniprotkb:Adenine nucleotide translocator 1(gene name synonym)|uniprotkb:ADP,ATP carrier protein 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 4(gene name synonym)|uniprotkb:ADP,ATP carrier protein, heart/skeletal muscle isoform T1(gene name synonym)|uniprotkb:AAC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_001142.2|ensembl:ENST00000281456(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0015866"(ADP transport)|ensembl:ENSG00000151729(gene)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12235|reactome:R-HSA-1268020|reactome:R-HSA-180897|reactome:R-HSA-83936|dip:DIP-33116N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:vs4XIUUUypcIHR9Lz4j1buDAnjM9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P35637 intact:EBI-6149678 intact:EBI-400434|uniprotkb:Q9H4A8|ensembl:ENSP00000254108 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:fus_human(display_long)|uniprotkb:FUS(gene name)|psi-mi:FUS(display_short)|uniprotkb:TLS(gene name synonym)|uniprotkb:Oncogene FUS(gene name synonym)|uniprotkb:Oncogene TLS(gene name synonym)|uniprotkb:Translocated in liposarcoma protein(gene name synonym)|uniprotkb:POMp75(gene name synonym)|uniprotkb:75 kDa DNA-pairing protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_001164105.1|refseq:NP_004951.1|ensembl:ENSG00000089280(gene)|ensembl:ENST00000254108(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008380"(RNA splicing)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044327"(dendritic spine head)|go:"GO:0046872"(metal ion binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034459|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:P35637|rcsb pdb:2LA6|rcsb pdb:2LCW|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:5W3N|rcsb pdb:5XRR|rcsb pdb:5XSG|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:6BWZ|rcsb pdb:6BXV|rcsb pdb:6BZP|rcsb pdb:6G99|rcsb pdb:6GBM|rcsb pdb:6KJ1|rcsb pdb:6KJ2|rcsb pdb:6KJ3|rcsb pdb:6KJ4|rcsb pdb:6SNJ|rcsb pdb:6XFM|rcsb pdb:7CYL|reactome:R-HSA-72163|dip:DIP-29857N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:HUP4fGXQyJnm5CFTuwjTpiucZOc9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P62269 intact:EBI-6149678 intact:EBI-352451|ensembl:ENSP00000211372|ensembl:ENSP00000393241|ensembl:ENSP00000403175|ensembl:ENSP00000412583|ensembl:ENSP00000416110|uniprotkb:P25232|uniprotkb:Q6IPF8|uniprotkb:Q5SUJ3 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:rs18_human(display_long)|uniprotkb:RPS18(gene name)|psi-mi:RPS18(display_short)|uniprotkb:D6S218E(gene name synonym)|uniprotkb:Ke-3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS13(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_072045.1|ensembl:ENSG00000096150(gene)|ensembl:ENSG00000223367(gene)|ensembl:ENSG00000226225(gene)|ensembl:ENSG00000231500(gene)|ensembl:ENSG00000235650(gene)|ensembl:ENST00000211372(transcript)|ensembl:ENST00000434122(transcript)|ensembl:ENST00000439602(transcript)|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENST00000454021(transcript)|ensembl:ENST00000457341(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001892(Ribosomal protein S13)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR018269|interpro:IPR027437|mint:P62269|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|dip:DIP-32892N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:yOHgKM/BuvgGdqp1OEVPeuiABg89606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P25398 intact:EBI-6149678 intact:EBI-354542|uniprotkb:Q76M58|ensembl:ENSP00000230050 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:rs12_human(display_long)|uniprotkb:RPS12(gene name)|psi-mi:RPS12(display_short)|uniprotkb:Small ribosomal subunit protein eS12(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_001007.2|ensembl:ENSG00000112306(gene)|ensembl:ENST00000230050(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR000530(Ribosomal protein S12e)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR029064|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72702|reactome:R-HSA-72695|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:80AIouzSdCvnLUSA7qsMp6naZ3g9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P31946 intact:EBI-6149678 intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P68104 intact:EBI-6149678 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P31943 intact:EBI-6149678 intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168|ensembl:ENSP00000377082|ensembl:ENSP00000397797|ensembl:ENSP00000492076|ensembl:ENSP00000495786 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_005511.1|refseq:NP_001244222.1|ensembl:ENSG00000169045(gene)|ensembl:ENSG00000284254(gene)|ensembl:ENST00000356731(transcript)|ensembl:ENST00000393432(transcript)|ensembl:ENST00000442819(transcript)|ensembl:ENST00000638505(transcript)|ensembl:ENST00000643310(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P52597 intact:EBI-6149678 intact:EBI-352986|ensembl:ENSP00000338477|ensembl:ENSP00000349573|ensembl:ENSP00000400433|ensembl:ENSP00000438061|ensembl:ENSP00000507787|ensembl:ENSP00000348345|uniprotkb:Q5T0N2|uniprotkb:Q96AU2|uniprotkb:B3KM84 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:hnrpf_human(display_long)|uniprotkb:HNRNPF(gene name)|psi-mi:HNRNPF(display_short)|uniprotkb:HNRPF(gene name synonym)|uniprotkb:Nucleolin-like protein mcs94-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P52597|rcsb pdb:2HGL|rcsb pdb:2HGM|rcsb pdb:2HGN|rcsb pdb:2KFY|rcsb pdb:2KG0|rcsb pdb:2KG1|rcsb pdb:3TFY|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensembl:ENSG00000169813(gene)|ensembl:ENST00000337970(transcript)|ensembl:ENST00000356053(transcript)|ensembl:ENST00000357065(transcript)|ensembl:ENST00000443950(transcript)|ensembl:ENST00000544000(transcript)|ensembl:ENST00000682386(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001091674.1|refseq:NP_001091675.1|refseq:NP_001091676.1|refseq:NP_001091677.1|refseq:NP_001091678.1|refseq:NP_004957.1|dip:DIP-33145N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:pblzpldZOa5vlZ+zGQY9qyWCxaw9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:Q99878 intact:EBI-6149678 intact:EBI-6147676|uniprotkb:Q5JXQ5|uniprotkb:A2RUU6|ensembl:ENSP00000328484 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:h2a1j_human(display_long)|uniprotkb:H2AC14(gene name)|psi-mi:H2AC14(display_short)|uniprotkb:H2AFE(gene name synonym)|uniprotkb:HIST1H2AJ(gene name synonym)|uniprotkb:Histone H2A/e(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_066544.1|ensembl:ENSG00000276368(gene)|ensembl:ENST00000333151(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:tS29VG3PpglHaYbu0w5z7pGvYyI9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P62736 intact:EBI-6149678 intact:EBI-698810|uniprotkb:P03996|uniprotkb:P04108|uniprotkb:Q6FI19|uniprotkb:B2R8A4|ensembl:ENSP00000224784 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:acta_human(display_long)|uniprotkb:Alpha-actin-2(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 46 protein(gene name synonym)|uniprotkb:ACTA2(gene name)|psi-mi:ACTA2(display_short)|uniprotkb:ACTSA(gene name synonym)|uniprotkb:ACTVS(gene name synonym)|uniprotkb:GIG46(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_001135417.1|refseq:NP_001604.1|refseq:NP_001307784.1|ensembl:ENSG00000107796(gene)|ensembl:ENST00000224784(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014829"(vascular associated smooth muscle contraction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072144"(glomerular mesangial cell development)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P62736|reactome:R-HSA-445355|reactome:R-HSA-9013695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:mRZGUdL/jBuj6nVHtxoasZuA7yA9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P07437 intact:EBI-6149678 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9WPI5 uniprotkb:P20671 intact:EBI-6149678 intact:EBI-4407441|uniprotkb:A0PK91|uniprotkb:P57754|uniprotkb:Q6FGY6|ensembl:ENSP00000341094 psi-mi:q9wpi5_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short) psi-mi:h2a1d_human(display_long)|uniprotkb:H2AC7(gene name)|psi-mi:H2AC7(display_short)|uniprotkb:H2AFG(gene name synonym)|uniprotkb:HIST1H2AD(gene name synonym)|uniprotkb:Histone H2A.3(gene name synonym)|uniprotkb:Histone H2A/g(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:380964("influenza a virus (a/texas/36/1991(h1n1))")|taxid:380964("Influenza A virus (A/Texas/36/1991(H1N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156643|imex:IM-17331-36 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR038064|go:"GO:0003723"(RNA binding) refseq:NP_066409.1|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000196866(gene)|ensembl:ENST00000341023(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:5GT3|rcsb pdb:6KBB|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2cqKw6DDUXCpBJNsGGZdOxdwNo4380964 rogid:Geraq+dGw3pvAAhgzzXQnYxDOOw9606 intact-crc:10DC3757048719EE|rigid:vpTwqm9PUNvpqExuHTxZG49nYX0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P69284 uniprotkb:Q9BQE3 intact:EBI-6149915 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:v_sendf(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11195(sendf)|taxid:11195("Sendai virus (strain Fushimi)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156862|imex:IM-17331-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-44949N|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR024279 reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:m1w7YFe987StIH/4BbuIBQEskVs11195 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:FDEB9BAF6F450AC1|rigid:Bc3UwMHHDBr66yrAnDqMnsxkLmM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P69284 uniprotkb:P22528 intact:EBI-6149915 intact:EBI-1058892|ensembl:ENSP00000306461|uniprotkb:B2R5H7|uniprotkb:P22529|uniprotkb:P22530|uniprotkb:Q5T524 psi-mi:v_sendf(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:spr1b_human(display_long)|uniprotkb:SPRR1B(gene name)|psi-mi:SPRR1B(display_short)|uniprotkb:Small proline-rich protein IB(gene name synonym)|uniprotkb:14.9 kDa pancornulin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11195(sendf)|taxid:11195("Sendai virus (strain Fushimi)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156862|imex:IM-17331-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-44949N|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR024279 ensembl:ENSG00000169469(gene)|ensembl:ENST00000307098(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|interpro:IPR003302("Cornifin (SPRR)")|mint:P22528|reactome:R-HSA-6809371|refseq:NP_003116.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:m1w7YFe987StIH/4BbuIBQEskVs11195 rogid:WU0vu+DHdIJm0x40HdcpAdJgdgo9606 intact-crc:FDEB9BAF6F450AC1|rigid:Bc3UwMHHDBr66yrAnDqMnsxkLmM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P69284 uniprotkb:P11021 intact:EBI-6149915 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:v_sendf(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11195(sendf)|taxid:11195("Sendai virus (strain Fushimi)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156862|imex:IM-17331-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-44949N|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR024279 ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:m1w7YFe987StIH/4BbuIBQEskVs11195 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 intact-crc:FDEB9BAF6F450AC1|rigid:Bc3UwMHHDBr66yrAnDqMnsxkLmM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P69284 uniprotkb:P35321 intact:EBI-6149915 intact:EBI-6149907|uniprotkb:Q2M303|uniprotkb:Q9UDG4|uniprotkb:D3DV31|uniprotkb:B1AN47|ensembl:ENSP00000357751 psi-mi:v_sendf(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:spr1a_human(display_long)|uniprotkb:SPRR1A(gene name)|psi-mi:SPRR1A(display_short)|uniprotkb:19 kDa pancornulin(gene name synonym)|uniprotkb:SPRK(gene name synonym)|uniprotkb:Small proline-rich protein IA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11195(sendf)|taxid:11195("Sendai virus (strain Fushimi)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156862|imex:IM-17331-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-44949N|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR024279 refseq:NP_001186757.1|refseq:NP_005978.2|ensembl:ENSG00000169474(gene)|ensembl:ENST00000368762(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0031424"(keratinization)|interpro:IPR003302("Cornifin (SPRR)")|reactome:R-HSA-6809371 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:m1w7YFe987StIH/4BbuIBQEskVs11195 rogid:SOf25yuBTrkh15zbAX99xnUe3ow9606 intact-crc:FDEB9BAF6F450AC1|rigid:Bc3UwMHHDBr66yrAnDqMnsxkLmM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P69284 uniprotkb:Q71U36 intact:EBI-6149915 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:v_sendf(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11195(sendf)|taxid:11195("Sendai virus (strain Fushimi)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156862|imex:IM-17331-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-44949N|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR024279 refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:m1w7YFe987StIH/4BbuIBQEskVs11195 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 intact-crc:FDEB9BAF6F450AC1|rigid:Bc3UwMHHDBr66yrAnDqMnsxkLmM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P69284 uniprotkb:Q06830 intact:EBI-6149915 intact:EBI-353193|ensembl:ENSP00000262746|ensembl:ENSP00000361152|ensembl:ENSP00000389047|ensembl:ENSP00000407034|ensembl:ENSP00000503140|uniprotkb:P35703|uniprotkb:Q2V576|uniprotkb:Q5T154|uniprotkb:Q5T155|uniprotkb:B5BU26|uniprotkb:D3DPZ8 psi-mi:v_sendf(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:prdx1_human(display_long)|uniprotkb:PRDX1(gene name)|psi-mi:PRDX1(display_short)|uniprotkb:PAGA(gene name synonym)|uniprotkb:PAGB(gene name synonym)|uniprotkb:TDPX2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Proliferation-associated gene protein(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor A(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11195(sendf)|taxid:11195("Sendai virus (strain Fushimi)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156862|imex:IM-17331-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-44949N|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR024279 ensembl:ENSG00000117450(gene)|ensembl:ENST00000262746(transcript)|ensembl:ENST00000319248(transcript)|ensembl:ENST00000424390(transcript)|ensembl:ENST00000447184(transcript)|ensembl:ENST00000676549(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003723"(RNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042470"(melanosome)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q06830|rcsb pdb:2RII|rcsb pdb:3HY2|rcsb pdb:4XCS|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803|refseq:NP_001189360.1|refseq:NP_002565.1|refseq:NP_859047.1|refseq:NP_859048.1|dip:DIP-33152N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:m1w7YFe987StIH/4BbuIBQEskVs11195 rogid:ZM5ZXF900izH81QVqgd2+opwMrs9606 intact-crc:FDEB9BAF6F450AC1|rigid:Bc3UwMHHDBr66yrAnDqMnsxkLmM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P69284 uniprotkb:P31151 intact:EBI-6149915 intact:EBI-357520|uniprotkb:Q6FGE3|uniprotkb:Q5SY67|uniprotkb:Q9H1E2|ensembl:ENSP00000357711|ensembl:ENSP00000357712 psi-mi:v_sendf(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:s10a7_human(display_long)|uniprotkb:S100A7(gene name)|psi-mi:S100A7(display_short)|uniprotkb:PSOR1(gene name synonym)|uniprotkb:S100A7C(gene name synonym)|uniprotkb:S100 calcium-binding protein A7(gene name synonym)|uniprotkb:Psoriasin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11195(sendf)|taxid:11195("Sendai virus (strain Fushimi)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156862|imex:IM-17331-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-44949N|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR024279 ensembl:ENSG00000143556(gene)|ensembl:ENST00000368722(transcript)|ensembl:ENST00000368723(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001525"(angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045087"(innate immune response)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051238"(sequestering of metal ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071624"(positive regulation of granulocyte chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028477|interpro:IPR034325|mint:P31151|rcsb pdb:1PSR|rcsb pdb:2PSR|rcsb pdb:2WND|rcsb pdb:2WOR|rcsb pdb:2WOS|rcsb pdb:3PSR|rcsb pdb:4AQJ|reactome:R-HSA-6798695|reactome:R-HSA-6799990|refseq:NP_002954.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:m1w7YFe987StIH/4BbuIBQEskVs11195 rogid:/v8+XQ7rCMTYzq9k/KqjcSm/G0A9606 intact-crc:FDEB9BAF6F450AC1|rigid:Bc3UwMHHDBr66yrAnDqMnsxkLmM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P69284 uniprotkb:P30153 intact:EBI-6149915 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:v_sendf(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11195(sendf)|taxid:11195("Sendai virus (strain Fushimi)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156862|imex:IM-17331-38 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-44949N|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR024279 ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:m1w7YFe987StIH/4BbuIBQEskVs11195 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 intact-crc:FDEB9BAF6F450AC1|rigid:Bc3UwMHHDBr66yrAnDqMnsxkLmM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6SW29 uniprotkb:Q96FJ2 intact:EBI-6149870|uniprotkb:D2K3S1 intact:EBI-742371|uniprotkb:B2R5B4|ensembl:ENSP00000477310 psi-mi:vie2_hcmvm(display_long)|uniprotkb:UL122(gene name)|psi-mi:UL122(display_short)|uniprotkb:Protein UL122(gene name synonym) psi-mi:dyl2_human(display_long)|uniprotkb:DYNLL2(gene name)|psi-mi:DYNLL2(display_short)|uniprotkb:Dynein light chain LC8-type 2(gene name synonym)|uniprotkb:DLC2(gene name synonym)|uniprotkb:8 kDa dynein light chain b(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:295027(hcmvm)|taxid:295027("Human cytomegalovirus (strain Merlin)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156832|imex:IM-17331-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005028(Herpes virus intermediate/early protein 2/3)|interpro:IPR010855(Cytomegalovirus IE1)|refseq:YP_081561.1|reactome:R-HSA-9609690|reactome:R-HSA-9610379|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) go:"GO:0005813"(centrosome)|refseq:NP_542408.1|ensembl:ENSG00000264364(gene)|ensembl:ENST00000579991(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007017"(microtubule-based process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0031475"(myosin V complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:Q96FJ2|rcsb pdb:2XQQ|rcsb pdb:3P8M|rcsb pdb:4D07|reactome:R-HSA-139910|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:9cAsXH6XGDQ353MuwlynMCYem8s295027 rogid:4RFpJF40RBja5mOvt/aCv3miiDU9606 intact-crc:369C5495606169FD|rigid:c14hp+lpOQmxn47ISK9U0UtDmyw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6SW29 uniprotkb:O00505 intact:EBI-6149870|uniprotkb:D2K3S1 intact:EBI-358297|intact:EBI-28976892|ensembl:ENSP00000261667|uniprotkb:O00191|uniprotkb:O43195|uniprotkb:Q96AA7|uniprotkb:Q5JVM9|intact:EBI-742146|uniprotkb:Q8IYQ9 psi-mi:vie2_hcmvm(display_long)|uniprotkb:UL122(gene name)|psi-mi:UL122(display_short)|uniprotkb:Protein UL122(gene name synonym) psi-mi:ima4_human(display_long)|uniprotkb:KPNA3(gene name)|psi-mi:KPNA3(display_short)|uniprotkb:QIP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym)|uniprotkb:SRP1-gamma(gene name synonym)|uniprotkb:Importin alpha Q2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:295027(hcmvm)|taxid:295027("Human cytomegalovirus (strain Merlin)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156832|imex:IM-17331-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005028(Herpes virus intermediate/early protein 2/3)|interpro:IPR010855(Cytomegalovirus IE1)|refseq:YP_081561.1|reactome:R-HSA-9609690|reactome:R-HSA-9610379|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000102753(gene)|ensembl:ENST00000261667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043657"(host cell)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000225(Armadillo)|refseq:NP_002258.2|ensembl:ENSP00000261667|dip:DIP-27586N|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00505|reactome:R-HSA-1169408|reactome:R-HSA-168276 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:9cAsXH6XGDQ353MuwlynMCYem8s295027 rogid:kx/oTYWMYG7dhwJHvr1POLD6FTU9606 intact-crc:369C5495606169FD|rigid:c14hp+lpOQmxn47ISK9U0UtDmyw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6SW29 uniprotkb:P08708 intact:EBI-6149870|uniprotkb:D2K3S1 intact:EBI-358255|uniprotkb:B2R4U4|intact:EBI-8012092|intact:EBI-11603362|intact:MINT-8395037|uniprotkb:P0CW22|ensembl:ENSP00000483755|ensembl:ENSP00000498019 psi-mi:vie2_hcmvm(display_long)|uniprotkb:UL122(gene name)|psi-mi:UL122(display_short)|uniprotkb:Protein UL122(gene name synonym) psi-mi:rs17_human(display_long)|uniprotkb:RPS17(gene name)|psi-mi:RPS17(display_short)|uniprotkb:Small ribosomal subunit protein eS17(gene name synonym)|uniprotkb:RPS17L(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:295027(hcmvm)|taxid:295027("Human cytomegalovirus (strain Merlin)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156832|imex:IM-17331-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005028(Herpes virus intermediate/early protein 2/3)|interpro:IPR010855(Cytomegalovirus IE1)|refseq:YP_081561.1|reactome:R-HSA-9609690|reactome:R-HSA-9610379|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_001012.1|ensembl:ENSG00000182774(gene)|ensembl:ENSG00000278229(gene)|ensembl:ENST00000617731(transcript)|ensembl:ENST00000647841(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR001210(Ribosomal protein S17e)|interpro:IPR018273|interpro:IPR036401|mint:P08708|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|go:"GO:0034101"(erythrocyte homeostasis)|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBS|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:9cAsXH6XGDQ353MuwlynMCYem8s295027 rogid:st+xQCXdSObiy6cJD1cSx869V289606 intact-crc:369C5495606169FD|rigid:c14hp+lpOQmxn47ISK9U0UtDmyw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6SW29 uniprotkb:P11021 intact:EBI-6149870|uniprotkb:D2K3S1 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:vie2_hcmvm(display_long)|uniprotkb:UL122(gene name)|psi-mi:UL122(display_short)|uniprotkb:Protein UL122(gene name synonym) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:295027(hcmvm)|taxid:295027("Human cytomegalovirus (strain Merlin)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156832|imex:IM-17331-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005028(Herpes virus intermediate/early protein 2/3)|interpro:IPR010855(Cytomegalovirus IE1)|refseq:YP_081561.1|reactome:R-HSA-9609690|reactome:R-HSA-9610379|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:9cAsXH6XGDQ353MuwlynMCYem8s295027 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 intact-crc:369C5495606169FD|rigid:c14hp+lpOQmxn47ISK9U0UtDmyw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6SW29 uniprotkb:P68400 intact:EBI-6149870|uniprotkb:D2K3S1 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 psi-mi:vie2_hcmvm(display_long)|uniprotkb:UL122(gene name)|psi-mi:UL122(display_short)|uniprotkb:Protein UL122(gene name synonym) psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:295027(hcmvm)|taxid:295027("Human cytomegalovirus (strain Merlin)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156832|imex:IM-17331-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005028(Herpes virus intermediate/early protein 2/3)|interpro:IPR010855(Cytomegalovirus IE1)|refseq:YP_081561.1|reactome:R-HSA-9609690|reactome:R-HSA-9610379|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:9cAsXH6XGDQ353MuwlynMCYem8s295027 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 intact-crc:369C5495606169FD|rigid:c14hp+lpOQmxn47ISK9U0UtDmyw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6SW29 uniprotkb:Q15326 intact:EBI-6149870|uniprotkb:D2K3S1 intact:EBI-2623509|intact:EBI-28967957|ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENSP00000381053|intact:EBI-2799565|uniprotkb:B2R6G8|uniprotkb:B7Z293|uniprotkb:F6UH50|uniprotkb:Q2LD45|uniprotkb:Q2LD46|uniprotkb:Q2LD47|uniprotkb:Q2LD48|uniprotkb:Q5VUI1|uniprotkb:Q8N4B3 psi-mi:vie2_hcmvm(display_long)|uniprotkb:UL122(gene name)|psi-mi:UL122(display_short)|uniprotkb:Protein UL122(gene name synonym) psi-mi:zmy11_human(display_long)|uniprotkb:BRAM1(gene name synonym)|uniprotkb:Bone morphogenetic protein receptor-associated molecule 1(gene name synonym)|uniprotkb:ZMYND11(gene name)|psi-mi:ZMYND11(display_short)|uniprotkb:Adenovirus 5 E1A-binding protein(gene name synonym)|uniprotkb:BS69(gene name synonym)|uniprotkb:Protein BS69(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:295027(hcmvm)|taxid:295027("Human cytomegalovirus (strain Merlin)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156832|imex:IM-17331-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005028(Herpes virus intermediate/early protein 2/3)|interpro:IPR010855(Cytomegalovirus IE1)|refseq:YP_081561.1|reactome:R-HSA-9609690|reactome:R-HSA-9610379|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENST00000381607|ensembl:ENSP00000371020|ensembl:ENST00000397959|ensembl:ENSP00000381050|ensembl:ENSP00000381053|ensembl:ENST00000509513|ensembl:ENSP00000424205|ensembl:ENST00000558098|ensembl:ENSP00000452959|ensembl:ENST00000602682|ensembl:ENSP00000473321|refseq:NP_001189396.1|refseq:NP_001189397.1|refseq:XP_016871076.1|refseq:XP_016871077.1|refseq:XP_016871078.1|refseq:XP_016871079.1|refseq:XP_016871081.1|refseq:XP_016871082.1|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051607"(defense response to virus)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR035505|interpro:IPR036427|mint:Q15326|rcsb pdb:4NS5|rcsb pdb:5HDA|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000015171(gene)|ensembl:ENST00000381591(transcript)|ensembl:ENST00000381604(transcript)|ensembl:ENST00000397962(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:XP_005252416.1|refseq:NP_001189393.1|refseq:NP_001189394.1|refseq:NP_006615.2|refseq:NP_997644.2|refseq:XP_005252418.1|refseq:XP_005252419.1|refseq:XP_006717439.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:9cAsXH6XGDQ353MuwlynMCYem8s295027 rogid:/QjUI+SjkfyB3GDHo7s09Sy1l4o9606 intact-crc:369C5495606169FD|rigid:c14hp+lpOQmxn47ISK9U0UtDmyw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6SW29 uniprotkb:P67870 intact:EBI-6149870|uniprotkb:D2K3S1 intact:EBI-348169|ensembl:ENSP00000365025|ensembl:ENSP00000365026|ensembl:ENSP00000365042|ensembl:ENSP00000372919|ensembl:ENSP00000372925|ensembl:ENSP00000382980|ensembl:ENSP00000390900|ensembl:ENSP00000391038|ensembl:ENSP00000393756|ensembl:ENSP00000394855|ensembl:ENSP00000395275|ensembl:ENSP00000400188|ensembl:ENSP00000407018|ensembl:ENSP00000407379|ensembl:ENSP00000409510|ensembl:ENSP00000410802|ensembl:ENSP00000411322|ensembl:ENSP00000412520|ensembl:ENSP00000413469|ensembl:ENSP00000415237|ensembl:ENSP00000415303|uniprotkb:P07312|uniprotkb:P13862|uniprotkb:Q4VX47|intact:EBI-3866975|uniprotkb:B0UXA9 psi-mi:vie2_hcmvm(display_long)|uniprotkb:UL122(gene name)|psi-mi:UL122(display_short)|uniprotkb:Protein UL122(gene name synonym) psi-mi:csk2b_human(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Protein G5a(gene name synonym)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:CK2N(gene name synonym)|uniprotkb:G5A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:295027(hcmvm)|taxid:295027("Human cytomegalovirus (strain Merlin)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156832|imex:IM-17331-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005028(Herpes virus intermediate/early protein 2/3)|interpro:IPR010855(Cytomegalovirus IE1)|refseq:YP_081561.1|reactome:R-HSA-9609690|reactome:R-HSA-9610379|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000204435(gene)|ensembl:ENSG00000230700(gene)|ensembl:ENSG00000206406(gene)|ensembl:ENSG00000232960(gene)|ensembl:ENSG00000224398(gene)|ensembl:ENSG00000224774(gene)|ensembl:ENSG00000228875(gene)|ensembl:ENST00000375882(transcript)|ensembl:ENST00000383427(transcript)|ensembl:ENST00000383433(transcript)|ensembl:ENST00000400110(transcript)|ensembl:ENST00000412802(transcript)|ensembl:ENST00000418230(transcript)|ensembl:ENST00000422567(transcript)|ensembl:ENST00000429633(transcript)|ensembl:ENST00000431476(transcript)|ensembl:ENST00000436169(transcript)|ensembl:ENST00000443673(transcript)|ensembl:ENST00000448596(transcript)|ensembl:ENST00000451917(transcript)|ensembl:ENST00000452985(transcript)|ensembl:ENST00000453234(transcript)|ensembl:ENST00000454382(transcript)|ensembl:ENST00000454511(transcript)|ensembl:ENST00000455161(transcript)|ensembl:ENST00000458330(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000375865(transcript)|ensembl:ENST00000375866(transcript)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034622"|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67870|rcsb pdb:1DS5|rcsb pdb:1JWH|go:"GO:0008134"(transcription factor binding)|rcsb pdb:1QF8|rcsb pdb:3EED|rcsb pdb:4DGL|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:6Q38|refseq:NP_001311.3|refseq:NP_001269314.1|dip:DIP-131N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:9cAsXH6XGDQ353MuwlynMCYem8s295027 rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg9606 intact-crc:369C5495606169FD|rigid:c14hp+lpOQmxn47ISK9U0UtDmyw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6SW29 uniprotkb:P63167 intact:EBI-6149870|uniprotkb:D2K3S1 intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907 psi-mi:vie2_hcmvm(display_long)|uniprotkb:UL122(gene name)|psi-mi:UL122(display_short)|uniprotkb:Protein UL122(gene name synonym) psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:295027(hcmvm)|taxid:295027("Human cytomegalovirus (strain Merlin)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156832|imex:IM-17331-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005028(Herpes virus intermediate/early protein 2/3)|interpro:IPR010855(Cytomegalovirus IE1)|refseq:YP_081561.1|reactome:R-HSA-9609690|reactome:R-HSA-9610379|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039646"(modulation by virus of host G0/G1 transition checkpoint)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:9cAsXH6XGDQ353MuwlynMCYem8s295027 rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606 intact-crc:369C5495606169FD|rigid:c14hp+lpOQmxn47ISK9U0UtDmyw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P90495 uniprotkb:Q9BQE3 intact:EBI-6149947|uniprotkb:O40920|uniprotkb:Q2HRC5 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:mir1_hhv8p(display_long)|uniprotkb:K3(gene name)|psi-mi:K3(display_short)|uniprotkb:IE1B protein(gene name synonym)|uniprotkb:Modulator of immune recognition 1(gene name synonym)|uniprotkb:ORF K3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MIR1(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:868565(hhv8p)|taxid:868565(Human herpesvirus 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156892|imex:IM-17331-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P90495|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:YP_001129360.1|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|rcsb pdb:1VYX reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:ltjmu2c6AbtXPA2Ybi6WSiF/e0w868565 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:CE68F3D1F0BC31A1|rigid:bjlAZdOu2UxTS48CLvjZoGriGR0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P90495 uniprotkb:O75787 intact:EBI-6149947|uniprotkb:O40920|uniprotkb:Q2HRC5 intact:EBI-2512037|ensembl:ENSP00000490083|uniprotkb:B7Z9I3|uniprotkb:Q8NG15|uniprotkb:Q8NBP3|uniprotkb:Q5QTQ7|uniprotkb:Q9UG89|uniprotkb:Q96FV6|uniprotkb:Q9H2P8|uniprotkb:Q96LB5|uniprotkb:Q6T7F5 psi-mi:mir1_hhv8p(display_long)|uniprotkb:K3(gene name)|psi-mi:K3(display_short)|uniprotkb:IE1B protein(gene name synonym)|uniprotkb:Modulator of immune recognition 1(gene name synonym)|uniprotkb:ORF K3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MIR1(gene name synonym) psi-mi:renr_human(display_long)|uniprotkb:ATP6AP2(gene name)|psi-mi:ATP6AP2(display_short)|uniprotkb:ATP6IP2(gene name synonym)|uniprotkb:CAPER(gene name synonym)|uniprotkb:ELDF10(gene name synonym)|uniprotkb:Renin/prorenin receptor(gene name synonym)|uniprotkb:"ATPase H(+)-transporting lysosomal accessory protein 2"(gene name synonym)|uniprotkb:"ATPase H(+)-transporting lysosomal-interacting protein 2"(gene name synonym)|uniprotkb:Vacuolar ATP synthase membrane sector-associated protein M8-9(gene name synonym)|uniprotkb:N14F(gene name synonym)|uniprotkb:Embryonic liver differentiation factor 10(gene name synonym)|uniprotkb:HT028(orf name)|uniprotkb:MSTP009(orf name)|uniprotkb:PSEC0072(orf name)|uniprotkb:ER-localized type I transmembrane adapter(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:868565(hhv8p)|taxid:868565(Human herpesvirus 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156892|imex:IM-17331-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P90495|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:YP_001129360.1|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|rcsb pdb:1VYX ensembl:ENSG00000182220(gene)|ensembl:ENST00000636580(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0002003"(angiotensin maturation)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0021626"(central nervous system maturation)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030424"(axon)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032914"(positive regulation of transforming growth factor beta1 production)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048069"(eye pigmentation)|go:"GO:0060323"(head morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR012493(Renin receptor-like)|mint:O75787|rcsb pdb:3LBS|rcsb pdb:3LC8|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-2022377|reactome:R-HSA-6798695|refseq:NP_005756.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:ltjmu2c6AbtXPA2Ybi6WSiF/e0w868565 rogid:v4lEPX23LdYqPi8dQX4MZG+tQZg9606 intact-crc:CE68F3D1F0BC31A1|rigid:bjlAZdOu2UxTS48CLvjZoGriGR0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P90495 uniprotkb:Q71U36 intact:EBI-6149947|uniprotkb:O40920|uniprotkb:Q2HRC5 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:mir1_hhv8p(display_long)|uniprotkb:K3(gene name)|psi-mi:K3(display_short)|uniprotkb:IE1B protein(gene name synonym)|uniprotkb:Modulator of immune recognition 1(gene name synonym)|uniprotkb:ORF K3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MIR1(gene name synonym) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:868565(hhv8p)|taxid:868565(Human herpesvirus 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156892|imex:IM-17331-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P90495|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:YP_001129360.1|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|rcsb pdb:1VYX refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:ltjmu2c6AbtXPA2Ybi6WSiF/e0w868565 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 intact-crc:CE68F3D1F0BC31A1|rigid:bjlAZdOu2UxTS48CLvjZoGriGR0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P90495 uniprotkb:Q8NC56 intact:EBI-6149947|uniprotkb:O40920|uniprotkb:Q2HRC5 intact:EBI-6149955|uniprotkb:Q5T972|uniprotkb:Q5T974|uniprotkb:B4DVH5|uniprotkb:E7EVT2|ensembl:ENSP00000293760|ensembl:ENSP00000478539 psi-mi:mir1_hhv8p(display_long)|uniprotkb:K3(gene name)|psi-mi:K3(display_short)|uniprotkb:IE1B protein(gene name synonym)|uniprotkb:Modulator of immune recognition 1(gene name synonym)|uniprotkb:ORF K3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MIR1(gene name synonym) psi-mi:lemd2_human(display_long)|uniprotkb:LEMD2(gene name)|psi-mi:LEMD2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:868565(hhv8p)|taxid:868565(Human herpesvirus 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156892|imex:IM-17331-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P90495|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:YP_001129360.1|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|rcsb pdb:1VYX refseq:NP_001335638.1|refseq:NP_851853.1|refseq:NP_001137416.1|ensembl:ENSG00000161904(gene)|ensembl:ENST00000293760(transcript)|ensembl:ENST00000614475(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022008"(neurogenesis)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060914"(heart formation)|go:"GO:0071168"(protein localization to chromatin)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR018996|interpro:IPR034994|interpro:IPR041885|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9668328 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:ltjmu2c6AbtXPA2Ybi6WSiF/e0w868565 rogid:mDTKCvVjxMtw3uYpitoTXSZHAYY9606 intact-crc:CE68F3D1F0BC31A1|rigid:bjlAZdOu2UxTS48CLvjZoGriGR0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P90495 uniprotkb:Q96HS1 intact:EBI-6149947|uniprotkb:O40920|uniprotkb:Q2HRC5 intact:EBI-713608|uniprotkb:Q96JB0|intact:EBI-2555528|ensembl:ENSP00000438465|uniprotkb:C9IZY7|uniprotkb:A9LN06 psi-mi:mir1_hhv8p(display_long)|uniprotkb:K3(gene name)|psi-mi:K3(display_short)|uniprotkb:IE1B protein(gene name synonym)|uniprotkb:Modulator of immune recognition 1(gene name synonym)|uniprotkb:ORF K3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MIR1(gene name synonym) psi-mi:pgam5_human(display_long)|uniprotkb:Bcl-XL-binding protein v68(gene name synonym)|uniprotkb:PGAM5(gene name)|psi-mi:PGAM5(display_short)|uniprotkb:Phosphoglycerate mutase family member 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:868565(hhv8p)|taxid:868565(Human herpesvirus 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156892|imex:IM-17331-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P90495|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:YP_001129360.1|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|rcsb pdb:1VYX refseq:NP_001164014.1|refseq:NP_612642.2|ensembl:ENSG00000247077(gene)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016791"(phosphatase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|mint:Q96HS1|rcsb pdb:3MXO|rcsb pdb:3O0T|rcsb pdb:5MUF|rcsb pdb:6CNI|rcsb pdb:6CNL|reactome:R-HSA-8934903|ensembl:ENST00000498926(transcript)|dip:DIP-50735N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:ltjmu2c6AbtXPA2Ybi6WSiF/e0w868565 rogid:prE0I+tNIEjN9Y1NBZbh51DY2+Q9606 intact-crc:CE68F3D1F0BC31A1|rigid:bjlAZdOu2UxTS48CLvjZoGriGR0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P90495 uniprotkb:Q6PEY2 intact:EBI-6149947|uniprotkb:O40920|uniprotkb:Q2HRC5 intact:EBI-2551023|ensembl:ENSP00000318197 psi-mi:mir1_hhv8p(display_long)|uniprotkb:K3(gene name)|psi-mi:K3(display_short)|uniprotkb:IE1B protein(gene name synonym)|uniprotkb:Modulator of immune recognition 1(gene name synonym)|uniprotkb:ORF K3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MIR1(gene name synonym) psi-mi:tba3e_human(display_long)|uniprotkb:Alpha-tubulin 3E(gene name synonym)|uniprotkb:TUBA3E(gene name)|psi-mi:TUBA3E(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:868565(hhv8p)|taxid:868565(Human herpesvirus 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156892|imex:IM-17331-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P90495|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:YP_001129360.1|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|rcsb pdb:1VYX ensembl:ENSG00000152086(gene)|ensembl:ENST00000312988(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-HSA-1445148|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5617833|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|refseq:NP_997195.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:ltjmu2c6AbtXPA2Ybi6WSiF/e0w868565 rogid:d1yeG615JSUxENnNbx2g6cUVWkI9606 intact-crc:CE68F3D1F0BC31A1|rigid:bjlAZdOu2UxTS48CLvjZoGriGR0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P90495 uniprotkb:P19338 intact:EBI-6149947|uniprotkb:O40920|uniprotkb:Q2HRC5 intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195 psi-mi:mir1_hhv8p(display_long)|uniprotkb:K3(gene name)|psi-mi:K3(display_short)|uniprotkb:IE1B protein(gene name synonym)|uniprotkb:Modulator of immune recognition 1(gene name synonym)|uniprotkb:ORF K3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MIR1(gene name synonym) psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:868565(hhv8p)|taxid:868565(Human herpesvirus 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156892|imex:IM-17331-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P90495|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:YP_001129360.1|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|rcsb pdb:1VYX refseq:NP_005372.2|dip:DIP-89N|ensembl:ENSG00000115053(gene)|ensembl:ENST00000322723(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005938"(cell cortex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:ltjmu2c6AbtXPA2Ybi6WSiF/e0w868565 rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606 intact-crc:CE68F3D1F0BC31A1|rigid:bjlAZdOu2UxTS48CLvjZoGriGR0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P90495 uniprotkb:P31151 intact:EBI-6149947|uniprotkb:O40920|uniprotkb:Q2HRC5 intact:EBI-357520|uniprotkb:Q6FGE3|uniprotkb:Q5SY67|uniprotkb:Q9H1E2|ensembl:ENSP00000357711|ensembl:ENSP00000357712 psi-mi:mir1_hhv8p(display_long)|uniprotkb:K3(gene name)|psi-mi:K3(display_short)|uniprotkb:IE1B protein(gene name synonym)|uniprotkb:Modulator of immune recognition 1(gene name synonym)|uniprotkb:ORF K3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MIR1(gene name synonym) psi-mi:s10a7_human(display_long)|uniprotkb:S100A7(gene name)|psi-mi:S100A7(display_short)|uniprotkb:PSOR1(gene name synonym)|uniprotkb:S100A7C(gene name synonym)|uniprotkb:S100 calcium-binding protein A7(gene name synonym)|uniprotkb:Psoriasin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:868565(hhv8p)|taxid:868565(Human herpesvirus 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156892|imex:IM-17331-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P90495|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:YP_001129360.1|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|rcsb pdb:1VYX ensembl:ENSG00000143556(gene)|ensembl:ENST00000368722(transcript)|ensembl:ENST00000368723(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001525"(angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045087"(innate immune response)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051238"(sequestering of metal ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071624"(positive regulation of granulocyte chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028477|interpro:IPR034325|mint:P31151|rcsb pdb:1PSR|rcsb pdb:2PSR|rcsb pdb:2WND|rcsb pdb:2WOR|rcsb pdb:2WOS|rcsb pdb:3PSR|rcsb pdb:4AQJ|reactome:R-HSA-6798695|reactome:R-HSA-6799990|refseq:NP_002954.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:ltjmu2c6AbtXPA2Ybi6WSiF/e0w868565 rogid:/v8+XQ7rCMTYzq9k/KqjcSm/G0A9606 intact-crc:CE68F3D1F0BC31A1|rigid:bjlAZdOu2UxTS48CLvjZoGriGR0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P90495 uniprotkb:Q00325 intact:EBI-6149947|uniprotkb:O40920|uniprotkb:Q2HRC5 intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34 psi-mi:mir1_hhv8p(display_long)|uniprotkb:K3(gene name)|psi-mi:K3(display_short)|uniprotkb:IE1B protein(gene name synonym)|uniprotkb:Modulator of immune recognition 1(gene name synonym)|uniprotkb:ORF K3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MIR1(gene name synonym) psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:868565(hhv8p)|taxid:868565(Human herpesvirus 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156892|imex:IM-17331-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P90495|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:YP_001129360.1|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|rcsb pdb:1VYX ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325 - - crc64:78714C85931B22D5 figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:ltjmu2c6AbtXPA2Ybi6WSiF/e0w868565 rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606 intact-crc:CE68F3D1F0BC31A1|rigid:bjlAZdOu2UxTS48CLvjZoGriGR0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P90495 uniprotkb:Q3ZAQ7 intact:EBI-6149947|uniprotkb:O40920|uniprotkb:Q2HRC5 intact:EBI-1055364|uniprotkb:B3KUA9|uniprotkb:A6NKV7|ensembl:ENSP00000333255 psi-mi:mir1_hhv8p(display_long)|uniprotkb:K3(gene name)|psi-mi:K3(display_short)|uniprotkb:IE1B protein(gene name synonym)|uniprotkb:Modulator of immune recognition 1(gene name synonym)|uniprotkb:ORF K3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MIR1(gene name synonym) psi-mi:vma21_human(display_long)|uniprotkb:VMA21(gene name)|psi-mi:VMA21(display_short)|uniprotkb:MEAX(gene name synonym)|uniprotkb:XMEA(gene name synonym)|uniprotkb:Myopathy with excessive autophagy protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:868565(hhv8p)|taxid:868565(Human herpesvirus 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156892|imex:IM-17331-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P90495|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:YP_001129360.1|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|rcsb pdb:1VYX refseq:NP_001017980.1|refseq:XP_011529427.1|ensembl:ENSG00000160131(gene)|ensembl:ENST00000330374(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|interpro:IPR019013 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:ltjmu2c6AbtXPA2Ybi6WSiF/e0w868565 rogid:HurJBmcAuXuwkMkJhQvwimpc99k9606 intact-crc:CE68F3D1F0BC31A1|rigid:bjlAZdOu2UxTS48CLvjZoGriGR0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P90495 uniprotkb:Q13748 intact:EBI-6149947|uniprotkb:O40920|uniprotkb:Q2HRC5 intact:EBI-355068|uniprotkb:A6NJQ0|uniprotkb:Q5W099|uniprotkb:Q6PEY3|uniprotkb:Q96F18|uniprotkb:P0DPH8|uniprotkb:P0DPH7 psi-mi:mir1_hhv8p(display_long)|uniprotkb:K3(gene name)|psi-mi:K3(display_short)|uniprotkb:IE1B protein(gene name synonym)|uniprotkb:Modulator of immune recognition 1(gene name synonym)|uniprotkb:ORF K3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MIR1(gene name synonym) psi-mi:tba3c_human(display_long)|uniprotkb:TUBA3C(gene name)|psi-mi:TUBA3C(display_short)|uniprotkb:TUBA3D(gene name)|psi-mi:TUBA3D(display_short)|uniprotkb:TUBA2(gene name synonym)|uniprotkb:Alpha-tubulin 3C/D(gene name synonym)|uniprotkb:Tubulin alpha-2 chain(gene name synonym)|uniprotkb:Alpha-tubulin 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:868565(hhv8p)|taxid:868565(Human herpesvirus 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156892|imex:IM-17331-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P90495|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:YP_001129360.1|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|rcsb pdb:1VYX go:"GO:0005200"(structural constituent of cytoskeleton)|ensembl:ENSG00000075886|ensembl:ENSG00000198033|ensembl:ENSP00000326042|ensembl:ENSP00000382982|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005525"(GTP binding)|go:"GO:0003924"(GTPase activity)|refseq:NP_005992.1|refseq:NP_525125.2|interpro:IPR002452(Alpha tubulin)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR000217(Tubulin)|interpro:IPR018316|interpro:IPR017975|interpro:IPR003008(Tubulin/FtsZ, GTPase)|ensembl:ENSP00000482878|ensembl:ENST00000618094|reactome:R-HSA-6807878|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-983189|go:"GO:0007017"(microtubule-based process)|go:"GO:0005634"(nucleus)|ensembl:ENST00000321253|ensembl:ENST00000400113|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-8852276|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR023123|mint:Q13748|dip:DIP-34513N|reactome:R-HSA-3371497|reactome:R-HSA-8955332|interpro:IPR036525|interpro:IPR037103|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0036064"(ciliary basal body) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:ltjmu2c6AbtXPA2Ybi6WSiF/e0w868565 rogid:mE1Hcdc9AAMMxfxzKB6TfM6RrHE9606 intact-crc:CE68F3D1F0BC31A1|rigid:bjlAZdOu2UxTS48CLvjZoGriGR0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P90495 uniprotkb:Q00839 intact:EBI-6149947|uniprotkb:O40920|uniprotkb:Q2HRC5 intact:EBI-351126|uniprotkb:O75507|uniprotkb:Q8N174|uniprotkb:Q96HY9|uniprotkb:Q9BQ09|ensembl:ENSP00000491215 psi-mi:mir1_hhv8p(display_long)|uniprotkb:K3(gene name)|psi-mi:K3(display_short)|uniprotkb:IE1B protein(gene name synonym)|uniprotkb:Modulator of immune recognition 1(gene name synonym)|uniprotkb:ORF K3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MIR1(gene name synonym) psi-mi:hnrpu_human(display_long)|uniprotkb:HNRNPU(gene name)|psi-mi:HNRNPU(display_short)|uniprotkb:SAFA(gene name synonym)|uniprotkb:U21.1(gene name synonym)|uniprotkb:HNRPU(gene name synonym)|uniprotkb:p120(gene name synonym)|uniprotkb:pp120(gene name synonym)|uniprotkb:C1orf199(gene name synonym)|uniprotkb:GRIP120(gene name synonym)|uniprotkb:Nuclear p120 ribonucleoprotein(gene name synonym)|uniprotkb:Scaffold-attachment factor A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:868565(hhv8p)|taxid:868565(Human herpesvirus 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156892|imex:IM-17331-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P90495|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:YP_001129360.1|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|rcsb pdb:1VYX refseq:NP_004492.2|refseq:NP_114032.2|ensembl:ENSG00000153187(gene)|ensembl:ENST00000640218(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:1990498"(mitotic spindle microtubule)|go:"GO:0098577"(inactive sex chromosome)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR026745|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q00839|rcsb pdb:1ZRJ|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990280"(RNA localization to chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006396"(RNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008143"("poly(A) binding")|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0017130"("poly(C) RNA binding")|go:"GO:0030496"(midbody)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|refseq:XP_016856604.1|refseq:XP_016856605.1|refseq:XP_016856606.1|dip:DIP-684N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:ltjmu2c6AbtXPA2Ybi6WSiF/e0w868565 rogid:n73PY0Vis+D5Iq0q77h5Ck2V4789606 intact-crc:CE68F3D1F0BC31A1|rigid:bjlAZdOu2UxTS48CLvjZoGriGR0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P90495 uniprotkb:Q15904 intact:EBI-6149947|uniprotkb:O40920|uniprotkb:Q2HRC5 intact:EBI-714667|uniprotkb:Q8NBT4|uniprotkb:Q9H0C7|uniprotkb:A6ZKI4|ensembl:ENSP00000358777 psi-mi:mir1_hhv8p(display_long)|uniprotkb:K3(gene name)|psi-mi:K3(display_short)|uniprotkb:IE1B protein(gene name synonym)|uniprotkb:Modulator of immune recognition 1(gene name synonym)|uniprotkb:ORF K3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MIR1(gene name synonym) psi-mi:vas1_human(display_long)|uniprotkb:V-ATPase S1 accessory protein(gene name synonym)|uniprotkb:V-ATPase Ac45 subunit(gene name synonym)|uniprotkb:Protein XAP-3(gene name synonym)|uniprotkb:ATP6AP1(gene name)|psi-mi:ATP6AP1(display_short)|uniprotkb:ATP6IP1(gene name synonym)|uniprotkb:ATP6S1(gene name synonym)|uniprotkb:VATPS1(gene name synonym)|uniprotkb:XAP3(gene name synonym)|uniprotkb:Vacuolar proton pump subunit S1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:868565(hhv8p)|taxid:868565(Human herpesvirus 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156892|imex:IM-17331-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P90495|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:YP_001129360.1|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|rcsb pdb:1VYX refseq:NP_001174.2|ensembl:ENSG00000071553(gene)|ensembl:ENST00000369762(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016469"(proton-transporting two-sector ATPase complex)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033180"(proton-transporting V-type ATPase, V1 domain)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045851"(pH reduction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:2001206"(positive regulation of osteoclast development)|interpro:IPR008388(ATPase, V1 complex, subunit S1)|mint:Q15904|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-77387|reactome:R-HSA-8980692|reactome:R-HSA-917977|reactome:R-HSA-983712|refseq:XP_011529481.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:ltjmu2c6AbtXPA2Ybi6WSiF/e0w868565 rogid:c5zqmRYvzBfRy1BdJteDGueEjY49606 intact-crc:CE68F3D1F0BC31A1|rigid:bjlAZdOu2UxTS48CLvjZoGriGR0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P90495 uniprotkb:Q9NZT1 intact:EBI-6149947|uniprotkb:O40920|uniprotkb:Q2HRC5 intact:EBI-1051681|uniprotkb:Q8IXU8|uniprotkb:Q5SQI3|ensembl:ENSP00000369689 psi-mi:mir1_hhv8p(display_long)|uniprotkb:K3(gene name)|psi-mi:K3(display_short)|uniprotkb:IE1B protein(gene name synonym)|uniprotkb:Modulator of immune recognition 1(gene name synonym)|uniprotkb:ORF K3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MIR1(gene name synonym) psi-mi:call5_human(display_long)|uniprotkb:Calmodulin-like skin protein(gene name synonym)|uniprotkb:CALML5(gene name)|psi-mi:CALML5(display_short)|uniprotkb:CLSP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:868565(hhv8p)|taxid:868565(Human herpesvirus 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156892|imex:IM-17331-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P90495|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:YP_001129360.1|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|rcsb pdb:1VYX refseq:NP_059118.2|ensembl:ENST00000380332(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0008544"(epidermis development)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q9NZT1|rcsb pdb:2B1U|reactome:R-HSA-6798695|ensembl:ENSG00000178372(gene) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:ltjmu2c6AbtXPA2Ybi6WSiF/e0w868565 rogid:uPD/avsoqpiogqHCK5TGJQwvCX89606 intact-crc:CE68F3D1F0BC31A1|rigid:bjlAZdOu2UxTS48CLvjZoGriGR0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P34931 uniprotkb:P90489 intact:EBI-354912|uniprotkb:O75634|uniprotkb:Q2HXR3|uniprotkb:Q8NE72|uniprotkb:A6NNB0|uniprotkb:Q96QC9|uniprotkb:Q9UQM1|uniprotkb:B0UXW8|ensembl:ENSP00000364805|ensembl:ENSP00000372881|ensembl:ENSP00000396486|ensembl:ENSP00000408347 intact:EBI-6150009|uniprotkb:D0UZM4|uniprotkb:Q2HRC0 psi-mi:hs71l_human(display_long)|uniprotkb:HSPA1L(gene name)|psi-mi:HSPA1L(display_short)|uniprotkb:Heat shock 70 kDa protein 1-Hom(gene name synonym) psi-mi:mir2_hhv8p(display_long)|uniprotkb:K5(gene name)|psi-mi:K5(display_short)|uniprotkb:IE1A protein(gene name synonym)|uniprotkb:Modulator of immune recognition 2(gene name synonym)|uniprotkb:ORF K5(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MIR2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:868565(hhv8p)|taxid:868565(Human herpesvirus 8) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156940|imex:IM-17331-40 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005518.3|ensembl:ENSG00000204390(gene)|ensembl:ENSG00000206383(gene)|ensembl:ENSG00000234258(gene)|ensembl:ENSG00000236251(gene)|ensembl:ENST00000375654(transcript)|ensembl:ENST00000383390(transcript)|ensembl:ENST00000417601(transcript)|ensembl:ENST00000456772(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0072562"(blood microparticle)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P34931|rcsb pdb:3GDQ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571 interpro:IPR001841(Zinc finger, RING-type)|mint:P90489|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|refseq:YP_001129365.1|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039504"(suppression by virus of host adaptive immune response)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0044078"(positive regulation by symbiont of host receptor-mediated endocytosis)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0075509"(endocytosis involved in viral entry into host cell) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:KS02DcMpD2sxSF36hUjKiSdYi4c9606 rogid:Rkqad9bfs+NNV26Z2bkng1xQ+4I868565 intact-crc:68F51CB1610A76BD|rigid:HKtFglXLU/2a8jc+jcPZU8uH+Wk false - tandem tag:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q9Y2I1 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-2688731|uniprotkb:Q6PIB4|uniprotkb:Q9UEU4|uniprotkb:Q7L8M3|uniprotkb:Q6PGP3|uniprotkb:Q9UFW3|uniprotkb:Q7Z2X6|uniprotkb:Q9UES6|uniprotkb:C9J245|ensembl:ENSP00000339958|ensembl:ENSP00000418232 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:nisch_human(display_long)|uniprotkb:IRAS(gene name synonym)|uniprotkb:KIAA0975(gene name synonym)|uniprotkb:Imidazoline receptor 1(gene name synonym)|uniprotkb:Imidazoline receptor antisera-selected protein(gene name synonym)|uniprotkb:Imidazoline-1 receptor(gene name synonym)|uniprotkb:Imidazoline-1 receptor candidate protein(gene name synonym)|uniprotkb:NISCH(gene name)|psi-mi:NISCH(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_009115.2|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048243"(norepinephrine secretion)|go:"GO:0055037"(recycling endosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001683(Phox-like)|interpro:IPR032675|interpro:IPR036871|interpro:IPR037904|mint:Q9Y2I1|rcsb pdb:3P0C|reactome:R-HSA-9013149|reactome:R-HSA-9696264|reactome:R-HSA-9696270|ensembl:ENSG00000010322(gene)|ensembl:ENST00000345716(transcript)|ensembl:ENST00000479054(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032228"(regulation of synaptic transmission, GABAergic)|refseq:NP_001263222.1|refseq:NP_001263223.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:GuBgG6MUrD5p1hIhGGmrtCjT0jQ9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P60660 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-300817|uniprotkb:P16475|uniprotkb:P24572|uniprotkb:P24573|uniprotkb:Q12790|ensembl:ENSP00000446955|ensembl:ENSP00000448101|uniprotkb:Q6IAZ0|uniprotkb:Q6IPY5|uniprotkb:Q561V9 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:myl6_human(display_long)|uniprotkb:MYL6(gene name)|psi-mi:MYL6(display_short)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6(gene name synonym)|uniprotkb:Myosin light chain alkali 3(gene name synonym)|uniprotkb:Myosin light chain 3(gene name synonym)|uniprotkb:17 kDa myosin light chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000092841(gene)|ensembl:ENST00000548293(transcript)|ensembl:ENST00000550697(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016020"(membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P60660|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:NP_066299.2|refseq:NP_524147.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:LhE3NUqcuHlOla13C0vjnFZfzy89606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P07900 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|ensembl:ENSP00000216281|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 go:"GO:0009409"(response to cold)|go:"GO:0016020"(membrane)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|ensembl:ENST00000216281(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000080824(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043335"(protein unfolding)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1UY8|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2BYH|rcsb pdb:2VCJ|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3B24|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5LO1|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6CYH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7LSZ|rcsb pdb:7LT0|reactome:R-HSA-1227986|reactome:R-HSA-1236382|rcsb pdb:6TN4|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9665233|reactome:R-HSA-9664565|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3K99|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:3T0H|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:4YKZ|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|refseq:NP_001017963.2|refseq:NP_005339.3|dip:DIP-27595N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P46782 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-350569|uniprotkb:Q96BN0|uniprotkb:B2R4T2|ensembl:ENSP00000196551|ensembl:ENSP00000470114|ensembl:ENSP00000472985 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs5_human(display_long)|uniprotkb:RPS5(gene name)|psi-mi:RPS5(display_short)|uniprotkb:Small ribosomal subunit protein uS7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001000.2|rcsb pdb:6OLZ|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6Z6M|rcsb pdb:6XA1|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6Y0G|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:5FLX|rcsb pdb:6OLG|rcsb pdb:6OLI|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72706|ensembl:ENSG00000083845(gene)|ensembl:ENST00000196551(transcript)|ensembl:ENST00000596046(transcript)|ensembl:ENST00000601521(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000235(Ribosomal protein S7)|interpro:IPR005716(Ribosomal protein S7, eukaryotic/archaeal)|interpro:IPR020606|interpro:IPR023798|interpro:IPR036823|mint:P46782|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:5AJ0|reactome:R-HSA-72702 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:SoCJdf2InngZZtlz5qD1k5CEfEo9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P42336 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-2116585|uniprotkb:Q14CW1|uniprotkb:Q99762|ensembl:ENSP00000263967 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pk3ca_human(display_long)|uniprotkb:Phosphoinositide-3-kinase catalytic alpha polypeptide(gene name synonym)|uniprotkb:Serine/threonine protein kinase PIK3CA(gene name synonym)|uniprotkb:PIK3CA(gene name)|psi-mi:PIK3CA(display_short)|uniprotkb:Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha(gene name synonym)|uniprotkb:Phosphoinositide 3-kinase alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:XP_011511196.1|refseq:XP_006713721.1|refseq:NP_006209.2|dip:DIP-42728N|ensembl:ENSG00000121879(gene)|ensembl:ENST00000263967(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001944"(vasculature development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0005944"(phosphatidylinositol 3-kinase complex, class IB)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006909"(phagocytosis)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030168"(platelet activation)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035004"(phosphatidylinositol 3-kinase activity)|go:"GO:0035005"(1-phosphatidylinositol-4-phosphate 3-kinase activity)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0038028"(insulin receptor signaling pathway via phosphatidylinositol 3-kinase)|go:"GO:0038084"(vascular endothelial growth factor signaling pathway)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0043276"(anoikis)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044029"(hypomethylation of CpG island)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046934"(phosphatidylinositol-4,5-bisphosphate 3-kinase activity)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110053"(regulation of actin filament organization)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR000341(Phosphoinositide 3-kinase, ras-binding)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR003113(Phosphatidylinositol 3-kinase, p85-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR029071|interpro:IPR035892|interpro:IPR036940|interpro:IPR037704|interpro:IPR042236|mint:P42336|rcsb pdb:2ENQ|rcsb pdb:2RD0|rcsb pdb:3HHM|rcsb pdb:3HIZ|rcsb pdb:3ZIM|rcsb pdb:4JPS|rcsb pdb:4L1B|rcsb pdb:4L23|rcsb pdb:4L2Y|rcsb pdb:4OVU|rcsb pdb:4OVV|rcsb pdb:4TUU|rcsb pdb:4TV3|rcsb pdb:4WAF|rcsb pdb:4YKN|rcsb pdb:4ZOP|rcsb pdb:5DXT|rcsb pdb:5FI4|rcsb pdb:5ITD|rcsb pdb:5SW8|rcsb pdb:5SWG|rcsb pdb:5SWO|rcsb pdb:5SWP|rcsb pdb:5SWR|rcsb pdb:5SWT|rcsb pdb:5SX8|rcsb pdb:5SX9|rcsb pdb:5SXA|rcsb pdb:5SXB|rcsb pdb:5SXC|rcsb pdb:5SXD|rcsb pdb:5SXE|rcsb pdb:5SXF|rcsb pdb:5SXI|rcsb pdb:5SXJ|rcsb pdb:5SXK|rcsb pdb:5UBR|rcsb pdb:5UK8|rcsb pdb:5UKJ|rcsb pdb:5UL1|rcsb pdb:5XGH|rcsb pdb:5XGI|rcsb pdb:5XGJ|rcsb pdb:6GVF|rcsb pdb:6GVG|rcsb pdb:6GVH|rcsb pdb:6GVI|rcsb pdb:6NCT|rcsb pdb:6OAC|rcsb pdb:6PYS|rcsb pdb:6VO7|rcsb pdb:7JIU|rcsb pdb:7K6M|rcsb pdb:7K6N|rcsb pdb:7K6O|rcsb pdb:7K71|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1236382|reactome:R-HSA-1250342|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-180292|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-1963642|reactome:R-HSA-198203|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654689|reactome:R-HSA-5654695|reactome:R-HSA-5654710|reactome:R-HSA-5654720|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-9009391|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9027276|reactome:R-HSA-9028335|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9603381|reactome:R-HSA-9607240|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|rcsb pdb:5DXH|reactome:R-HSA-9703465|reactome:R-HSA-9703648 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:YIZWt9VfCmyBCWYkqAEaMAEsl3w9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q9HAV0 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-358539|uniprotkb:B3KMH5|uniprotkb:D3DNR8|ensembl:ENSP00000501882|ensembl:ENSP00000502628|ensembl:ENSP00000232564 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:gbb4_human(display_long)|uniprotkb:GNB4(gene name)|psi-mi:GNB4(display_short)|uniprotkb:Transducin beta chain 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_067642.1|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272|reactome:R-HSA-456926|ensembl:ENSG00000114450(gene)|ensembl:ENST00000232564(transcript)|ensembl:ENST00000674862(transcript)|ensembl:ENST00000676128(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0021762"(substantia nigra development)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9HAV0|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-381676|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|refseq:XP_006713784.1|refseq:XP_005247749.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:L6hFuZe1Luk8YTFW+posXDa2Qj49606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P62879 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-356942|uniprotkb:P54312|uniprotkb:P11016|uniprotkb:B3KPU1|ensembl:ENSP00000305260|ensembl:ENSP00000377501|ensembl:ENSP00000377503 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:gbb2_human(display_long)|uniprotkb:GNB2(gene name)|psi-mi:GNB2(display_short)|uniprotkb:Transducin beta chain 2(gene name synonym)|uniprotkb:G protein subunit beta-2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_005264.2|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0031982"(vesicle)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051020"(GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P62879|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-381676|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|reactome:R-HSA-456926|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272|go:"GO:0016020"(membrane)|ensembl:ENSG00000172354(gene)|ensembl:ENST00000303210(transcript)|ensembl:ENST00000393924(transcript)|ensembl:ENST00000393926(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007186"(G protein-coupled receptor signaling pathway) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:dingPUxdpAhe7UMLquv0eqXNtUM9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P07437 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P07195 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-358748|ensembl:ENSP00000229319|ensembl:ENSP00000379386 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ldhb_human(display_long)|uniprotkb:LDHB(gene name)|psi-mi:LDHB(display_short)|uniprotkb:LDH heart subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001167568.1|refseq:NP_002291.1|refseq:NP_001302466.1|ensembl:ENSG00000111716(gene)|ensembl:ENST00000350669(transcript)|ensembl:ENST00000396076(transcript)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|mint:P07195|rcsb pdb:1I0Z|rcsb pdb:1T2F|reactome:R-HSA-70268 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:umdj6fjSO7+4SM9Hrl1/K2EiKls9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P68371 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q9Y265 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-353675|uniprotkb:P82276|uniprotkb:Q1KMR0|uniprotkb:Q53HK5|uniprotkb:Q53HL7|uniprotkb:Q53Y27|uniprotkb:Q9BSX9|uniprotkb:B2R5S0|ensembl:ENSP00000318297|ensembl:ENSP00000494621 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ruvb1_human(display_long)|uniprotkb:RUVBL1(gene name)|psi-mi:RUVBL1(display_short)|uniprotkb:NMP238(gene name synonym)|uniprotkb:TIP49(gene name synonym)|uniprotkb:TIP49A(gene name synonym)|uniprotkb:49 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49a(gene name synonym)|uniprotkb:Pontin 52(gene name synonym)|uniprotkb:Nuclear matrix protein 238(gene name synonym)|uniprotkb:54 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80H(gene name synonym)|uniprotkb:TIP60-associated protein 54-alpha(gene name synonym)|uniprotkb:INO80 complex subunit H(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_003698.1|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:Q9Y265|rcsb pdb:2C9O|rcsb pdb:2XSZ|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|reactome:R-HSA-201722|reactome:R-HSA-3214847|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5696394|reactome:R-HSA-606279|ensembl:ENSG00000175792(gene)|ensembl:ENSG00000284901(gene)|ensembl:ENST00000322623(transcript)|ensembl:ENST00000643444(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|refseq:NP_001306013.1|dip:DIP-29937N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:+FA/xQTUldQoWGRgad9U8vZpTHw9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P16520 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-2880663|uniprotkb:Q9BQC0|uniprotkb:Q96B71|ensembl:ENSP00000229264 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:gbb3_human(display_long)|uniprotkb:GNB3(gene name)|psi-mi:GNB3(display_short)|uniprotkb:Transducin beta chain 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 dip:DIP-601N|refseq:NP_001284500.1|refseq:NP_002066.1|ensembl:ENSG00000111664(gene)|ensembl:ENST00000229264(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0030425"(dendrite)|go:"GO:0030507"(spectrin binding)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0044297"(cell body)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0051020"(GTPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0090207"(regulation of triglyceride metabolic process)|go:"GO:1903725"(regulation of phospholipid metabolic process)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-381676|reactome:R-HSA-381771|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|reactome:R-HSA-456926|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:hYRSnueBN7eZ3RZtnP6WnOPTX3A9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P08238 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:wOsW7C10v2oMsM+REE38K6PAan09606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P62158 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q9Y230 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352939|ensembl:ENSP00000473172|uniprotkb:Q6FIB9|uniprotkb:Q6PK27|uniprotkb:Q9Y361|uniprotkb:B3KQ59|uniprotkb:E7ETE5|intact:EBI-1058527 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ruvb2_human(display_long)|uniprotkb:RUVBL2(gene name)|psi-mi:RUVBL2(display_short)|uniprotkb:TIP48(gene name synonym)|uniprotkb:TIP49B(gene name synonym)|uniprotkb:CGI-46(orf name)|uniprotkb:48 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49b(gene name synonym)|uniprotkb:Repressing pontin 52(gene name synonym)|uniprotkb:51 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80J(gene name synonym)|uniprotkb:TIP60-associated protein 54-beta(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487|mint:Q9Y230|rcsb pdb:2CQA|rcsb pdb:2XSZ|rcsb pdb:3UK6|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6H7X|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|go:"GO:0140585"(promoter-enhancer loop anchoring activity)|reactome:R-HSA-3214847|ensembl:ENSG00000183207(gene)|ensembl:ENST00000595090(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000791"(euchromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006457"(protein folding)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0016573"(histone acetylation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|refseq:NP_006657.1|refseq:XP_011524632.1|refseq:NP_001308120.1|dip:DIP-28153N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:APKAWLDCJVULUP3nzqIaSLHKVN49606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q9NNW5 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1568315|uniprotkb:B4DHK2|uniprotkb:Q3MIT1|uniprotkb:Q9UF63|ensembl:ENSP00000477389 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:wdr6_human(display_long)|uniprotkb:WDR6(gene name)|psi-mi:WDR6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_060501.3|refseq:NP_001307475.1|refseq:NP_001307476.1|ensembl:ENSG00000178252(gene)|ensembl:ENST00000608424(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0030488"(tRNA methylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9NNW5|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:gYSDkyuDdKhj387/1P3bhpKJXy89606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P62258 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P35580 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-351758|intact:EBI-7850240|intact:MINT-8330016|uniprotkb:B2RWP9|uniprotkb:D3DTS1|uniprotkb:Q9BWG0|uniprotkb:Q12989|uniprotkb:Q16087|uniprotkb:Q149N3|ensembl:ENSP00000269243|uniprotkb:Q149N4|uniprotkb:Q6PK16|uniprotkb:F8VTL3|uniprotkb:Q4LE45 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:myh10_human(display_long)|uniprotkb:MYH10(gene name)|psi-mi:MYH10(display_short)|uniprotkb:Myosin heavy chain 10(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIb(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIb(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type B(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001243024.1|refseq:NP_001242941.1|refseq:NP_005955.3|ensembl:ENSG00000133026(gene)|ensembl:ENST00000269243(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016459"(myosin complex)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042641"(actomyosin)|go:"GO:0043531"(ADP binding)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097513"(myosin II filament)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:P35580|rcsb pdb:4PD3|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:XP_016880169.1|refseq:XP_016880170.1|refseq:XP_016880171.1|dip:DIP-31110N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:iSHfJZbrWg1L+vSpu1n7RmTTNN49606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q5VTE0 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-877809 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ef1a3_human(display_long)|uniprotkb:EEF1A1P5(gene name)|psi-mi:EEF1A1P5(display_short)|uniprotkb:Eukaryotic elongation factor 1 A-like 3(gene name synonym)|uniprotkb:EEF1AL3(gene name synonym)|uniprotkb:Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR031157|reactome:R-HSA-156842|interpro:IPR027417 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:3t6tj3i+3CKTC1NsrHyBkeoRK789606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q3ZCQ8 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-355175|uniprotkb:Q6QA00|uniprotkb:Q96FJ5|uniprotkb:Q96GY2|uniprotkb:Q9H370|intact:EBI-2554785|uniprotkb:Q330K1|ensembl:ENSP00000475531 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:tim50_human(display_long)|uniprotkb:TIMM50(gene name)|psi-mi:TIMM50(display_short)|uniprotkb:TIM50(gene name synonym)|uniprotkb:PRO1512(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001001563.1|ensembl:ENSG00000105197(gene)|ensembl:ENST00000607714(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003723"(RNA binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005134"(interleukin-2 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007006"(mitochondrial membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR004274(NLI interacting factor)|interpro:IPR023214|interpro:IPR027111|interpro:IPR036412|mint:Q3ZCQ8|reactome:R-HSA-1268020|refseq:NP_001316488.1|dip:DIP-34058N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:fOPV33h12YhAq9jj0bVno01Q+6g9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:O14654 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-356594|ensembl:ENSP00000505547 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q562R1 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1773495|uniprotkb:Q562R2|uniprotkb:Q562S9|uniprotkb:Q562X8|uniprotkb:B2RPJ1|ensembl:ENSP00000416706 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:actbl_human(display_long)|uniprotkb:ACTBL2(gene name)|psi-mi:ACTBL2(display_short)|uniprotkb:Kappa-actin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001017992.1|ensembl:ENSG00000169067(gene)|ensembl:ENST00000423391(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0007409"(axonogenesis)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0045202"(synapse)|go:"GO:0048870"(cell motility)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:Q562R1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:GTzKP5YRJGH8ocAJW0WEsdQFEdc9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P60174 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-717475|uniprotkb:D3DUS9|uniprotkb:P00938|uniprotkb:Q6IS07|uniprotkb:Q8WWD0|uniprotkb:Q96AG5|uniprotkb:Q6FHP9|uniprotkb:B7Z5D8|ensembl:ENSP00000379933 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:tpis_human(display_long)|uniprotkb:Triose-phosphate isomerase(gene name synonym)|uniprotkb:TPI1(gene name)|psi-mi:TPI1(display_short)|uniprotkb:TPI(gene name synonym)|uniprotkb:Methylglyoxal synthase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_000356.1|refseq:NP_001152759.1|refseq:NP_001244955.1|ensembl:ENSG00000111669(gene)|ensembl:ENST00000396705(transcript)|go:"GO:0004807"(triose-phosphate isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0008929"(methylglyoxal synthase activity)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000652(Triosephosphate isomerase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR020861|interpro:IPR022896|interpro:IPR035990|mint:P60174|rcsb pdb:1HTI|rcsb pdb:1KLG|rcsb pdb:1KLU|rcsb pdb:1WYI|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2JK2|rcsb pdb:2VOM|rcsb pdb:4BR1|rcsb pdb:4E41|rcsb pdb:4POC|rcsb pdb:4POD|rcsb pdb:4UNK|rcsb pdb:4UNL|rcsb pdb:4ZVJ|rcsb pdb:6C2G|rcsb pdb:6D43|rcsb pdb:6NLH|rcsb pdb:6UP1|rcsb pdb:6UP5|rcsb pdb:6UP8|rcsb pdb:6UPF|reactome:R-HSA-70171|reactome:R-HSA-70263 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:FaLt6wGI1Bz2Z81gX35p7sOiMbE9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P22087 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-358318|uniprotkb:O75259|uniprotkb:Q6IAT5|uniprotkb:Q9UPI6|ensembl:ENSP00000221801|ensembl:ENSP00000487390|uniprotkb:B5BUE8 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:fbrl_human(display_long)|uniprotkb:FBL(gene name)|psi-mi:FBL(display_short)|uniprotkb:FIB1(gene name synonym)|uniprotkb:FLRN(gene name synonym)|uniprotkb:Histone-glutamine methyltransferase(gene name synonym)|uniprotkb:34 kDa nucleolar scleroderma antigen(gene name synonym)|uniprotkb:U6 snRNA 2'-O-methyltransferase fibrillarin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001427.2|ensembl:ENSG00000105202(gene)|ensembl:ENSG00000280548(gene)|ensembl:ENST00000221801(transcript)|ensembl:ENST00000625241(transcript)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0001652"(granular component)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0008649"(rRNA methyltransferase activity)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0031167"(rRNA methylation)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0048254"(snoRNA localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990258"(histone glutamine methylation)|go:"GO:1990259"(histone-glutamine methyltransferase activity)|interpro:IPR000692(Fibrillarin)|interpro:IPR020813|interpro:IPR029063|mint:P22087|rcsb pdb:2IPX|reactome:R-HSA-6790901|reactome:R-HSA-6791226|dip:DIP-27569N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:8m8FDRSxGNKNXpJMcWWbcHL3uss9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P12277 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-357706|uniprotkb:Q2LE07|uniprotkb:A8K236|uniprotkb:B2R5R4|uniprotkb:Q6FG40|uniprotkb:Q9UC66|ensembl:ENSP00000299198 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:kcrb_human(display_long)|uniprotkb:CKB(gene name)|psi-mi:CKB(display_short)|uniprotkb:CKBB(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:Brain creatine kinase(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001814.2|go:"GO:0005829"(cytosol)|ensembl:ENSG00000166165(gene)|ensembl:ENST00000348956(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12277|rcsb pdb:3B6R|rcsb pdb:3DRB|rcsb pdb:3DRE|rcsb pdb:6V9H|go:"GO:0021762"(substantia nigra development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|reactome:R-HSA-71288|reactome:R-HSA-9696264|dip:DIP-52968N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:WLRnU8sRUfJQoaPY0edGi9xiR+g9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q8NHW5 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-355416 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rla0l_human(display_long)|uniprotkb:RPLP0P6(gene name)|psi-mi:RPLP0P6(display_short)|uniprotkb:Large ribosomal subunit protein uL10-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 interpro:IPR001790(Ribosomal protein L10)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|interpro:IPR040637|interpro:IPR030670|interpro:IPR043141|interpro:IPR043164 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:mwr/+G18VKkJ2yrEjIMbz9m058o9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P27986 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-79464|intact:EBI-28974553|ensembl:ENSP00000428056|ensembl:ENSP00000429277|uniprotkb:Q15747|uniprotkb:Q4VBZ7|uniprotkb:Q53EM6|uniprotkb:Q8IXA2|uniprotkb:Q8N1C5|uniprotkb:D3DWA0|uniprotkb:B3KT19|uniprotkb:E7EX19 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:p85a_human(display_long)|uniprotkb:PIK3R1(gene name)|psi-mi:PIK3R1(display_short)|uniprotkb:GRB1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001229395.1|refseq:NP_852556.2|refseq:NP_852664.1|refseq:NP_852665.1|ensembl:ENSG00000145675(gene)|ensembl:ENST00000521381(transcript)|ensembl:ENST00000521657(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|ensembl:ENST00000320694|ensembl:ENSP00000323512|ensembl:ENST00000336483|ensembl:ENSP00000338554|ensembl:ENSP00000428056|ensembl:ENSP00000429277|ensembl:ENST00000523872|ensembl:ENSP00000430098|rcsb pdb:5SXA|rcsb pdb:5SXB|rcsb pdb:5SXC|rcsb pdb:5SXD|rcsb pdb:5SXE|rcsb pdb:5SXF|rcsb pdb:5SXI|rcsb pdb:5SXJ|rcsb pdb:5SXK|rcsb pdb:5UBT|rcsb pdb:5UK8|rcsb pdb:5UKJ|rcsb pdb:5SX9|rcsb pdb:5UL1|rcsb pdb:5VLR|rcsb pdb:5XGH|rcsb pdb:5XGI|rcsb pdb:5XGJ|rcsb pdb:6NCT|rcsb pdb:6PYR|rcsb pdb:6PYU|reactome:R-HSA-1660499|rcsb pdb:7CIO|rcsb pdb:7LM2|reactome:R-HSA-180292|reactome:R-HSA-109704|reactome:R-HSA-1839117|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1236382|reactome:R-HSA-186763|reactome:R-HSA-1963642|reactome:R-HSA-1250342|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-198203|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-1433557|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-430116|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654689|reactome:R-HSA-5654695|reactome:R-HSA-5654710|reactome:R-HSA-5654720|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9603381|reactome:R-HSA-9607240|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-983695|reactome:R-HSA-5655253|reactome:R-HSA-5655302|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-6811558|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-5655291|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9027276|reactome:R-HSA-9028335|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0043559"(insulin binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1990578"(perinuclear endoplasmic reticulum membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035591|interpro:IPR036028|interpro:IPR036860|interpro:IPR044124|mint:P27986|rcsb pdb:1A0N|rcsb pdb:1AZG|rcsb pdb:1H9O|rcsb pdb:1PBW|rcsb pdb:1PHT|rcsb pdb:1PIC|rcsb pdb:1PKS|rcsb pdb:1PKT|rcsb pdb:2IUG|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|rcsb pdb:2IUH|rcsb pdb:2IUI|rcsb pdb:2RD0|rcsb pdb:3HHM|rcsb pdb:3HIZ|rcsb pdb:3I5R|rcsb pdb:3I5S|rcsb pdb:4A55|rcsb pdb:4JPS|rcsb pdb:4L1B|rcsb pdb:4L23|rcsb pdb:4L2Y|rcsb pdb:4OVU|rcsb pdb:4OVV|rcsb pdb:4WAF|rcsb pdb:4YKN|rcsb pdb:4ZOP|rcsb pdb:5AUL|rcsb pdb:5FI4|rcsb pdb:5GJI|rcsb pdb:5ITD|rcsb pdb:5M6U|rcsb pdb:5SW8|rcsb pdb:5SWG|rcsb pdb:5SWO|rcsb pdb:2V1Y|rcsb pdb:5SWP|rcsb pdb:5SWR|rcsb pdb:5SWT|rcsb pdb:5SX8|refseq:XP_016865074.1|refseq:XP_005248599.1|dip:DIP-119N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:pANLtVCSWVr64OXaS6bCjGBwfig9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q05639 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-354943|ensembl:ENSP00000217182|uniprotkb:P54266|uniprotkb:Q0VGC7|uniprotkb:B5BUF3|uniprotkb:E1P5J1 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ef1a2_human(display_long)|uniprotkb:EEF1A2(gene name)|psi-mi:EEF1A2(display_short)|uniprotkb:EEF1AL(gene name synonym)|uniprotkb:STN(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-2(gene name synonym)|uniprotkb:Statin-S1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000101210(gene)|ensembl:ENST00000217182(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0090218"(positive regulation of lipid kinase activity)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:Q05639|rcsb pdb:3C5J|reactome:R-HSA-156842|refseq:NP_001949.1|dip:DIP-40060N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:vFXfcSRokxKo5RW0tRE1qEK0NKw9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P62873 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-357130|ensembl:ENSP00000367872|ensembl:ENSP00000481878|uniprotkb:P04901|uniprotkb:P04697|uniprotkb:B1AJZ7|uniprotkb:Q1RMY8 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:gbb1_human(display_long)|uniprotkb:GNB1(gene name)|psi-mi:GNB1(display_short)|uniprotkb:Transducin beta chain 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P62873|rcsb pdb:4KFM|rcsb pdb:4PNK|rcsb pdb:5HE0|rcsb pdb:5HE1|rcsb pdb:5HE2|rcsb pdb:5HE3|rcsb pdb:5UKK|rcsb pdb:5UKL|rcsb pdb:5UKM|rcsb pdb:5UZ7|rcsb pdb:6B3J|rcsb pdb:6CRK|rcsb pdb:6D9H|rcsb pdb:6DDE|rcsb pdb:6DDF|rcsb pdb:6E3Y|rcsb pdb:6EG8|rcsb pdb:6G79|rcsb pdb:6GDG|rcsb pdb:6KPF|rcsb pdb:6KPG|go:"GO:1903561"(extracellular vesicle)|rcsb pdb:6LFM|rcsb pdb:6LFO|rcsb pdb:6LI3|rcsb pdb:6LMK|rcsb pdb:6LML|rcsb pdb:6M1H|rcsb pdb:6M1I|rcsb pdb:6M8S|rcsb pdb:6N4B|rcsb pdb:6NI3|rcsb pdb:6NIY|rcsb pdb:6OIJ|rcsb pdb:6OIK|rcsb pdb:6OMM|rcsb pdb:6ORV|rcsb pdb:6OS9|rcsb pdb:6OSA|rcsb pdb:6OT0|rcsb pdb:6P9X|rcsb pdb:6P9Y|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6PT0|rcsb pdb:6UUN|rcsb pdb:6UUS|rcsb pdb:6UVA|rcsb pdb:6VCB|rcsb pdb:6VMS|rcsb pdb:6VN7|rcsb pdb:6WHA|rcsb pdb:6WHC|rcsb pdb:6WI9|rcsb pdb:6WPW|rcsb pdb:6WZG|rcsb pdb:6X18|rcsb pdb:6X19|rcsb pdb:6X1A|rcsb pdb:6XBJ|rcsb pdb:6XBK|rcsb pdb:6XBL|rcsb pdb:6XBM|rcsb pdb:6XOX|rcsb pdb:7AUE|rcsb pdb:7BB6|rcsb pdb:7BB7|rcsb pdb:7C2E|rcsb pdb:7CFM|rcsb pdb:7CFN|rcsb pdb:7CKW|rcsb pdb:7CKX|rcsb pdb:7CKY|rcsb pdb:7CKZ|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7CRH|rcsb pdb:7CX2|rcsb pdb:7CX4|rcsb pdb:7D76|rcsb pdb:7D77|rcsb pdb:7D7M|rcsb pdb:7DFL|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7E9G|rcsb pdb:7E9H|rcsb pdb:7CX3|rcsb pdb:7EB2|rcsb pdb:7JOZ|rcsb pdb:7JV5|rcsb pdb:7JVP|rcsb pdb:7JVQ|rcsb pdb:7JVR|rcsb pdb:7K7L|rcsb pdb:7K7Z|rcsb pdb:7KH0|rcsb pdb:7L0P|rcsb pdb:7L0Q|rcsb pdb:7L0R|rcsb pdb:7L0S|rcsb pdb:7L1U|rcsb pdb:7L1V|rcsb pdb:7LCI|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-2485179|reactome:R-HSA-2514859|reactome:R-HSA-381676|reactome:R-HSA-381753|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|reactome:R-HSA-456926|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272|ensembl:ENST00000610897(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030507"(spectrin binding)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0051020"(GTPase binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071870"(cellular response to catecholamine stimulus)|go:"GO:0097381"(photoreceptor disc membrane)|ensembl:ENSG00000078369(gene)|ensembl:ENST00000378609(transcript)|refseq:NP_001269467.1|refseq:NP_001269468.1|dip:DIP-599N|refseq:NP_002065.1|refseq:XP_016856548.1|refseq:XP_016856549.1|refseq:XP_016856550.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:zP/G70MXiSQpzbyyWFTWrJFQENk9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P10809 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352528|ensembl:ENSP00000340019|ensembl:ENSP00000373620|ensembl:ENSP00000396460|ensembl:ENSP00000402478|ensembl:ENSP00000412227|ensembl:ENSP00000412717|ensembl:ENSP00000414446|ensembl:ENSP00000503139|ensembl:ENSP00000503894|uniprotkb:Q38L19|uniprotkb:B2R5M6|uniprotkb:Q9UCR6|uniprotkb:B7Z712 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ch60_human(display_long)|uniprotkb:HSPD1(gene name)|psi-mi:HSPD1(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:P60 lymphocyte protein(gene name synonym)|uniprotkb:HuCHA60(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_002147.2|refseq:NP_955472.1|ensembl:ENSG00000144381(gene)|ensembl:ENST00000345042(transcript)|ensembl:ENST00000388968(transcript)|ensembl:ENST00000418022(transcript)|ensembl:ENST00000426480(transcript)|ensembl:ENST00000428204(transcript)|ensembl:ENST00000439605(transcript)|ensembl:ENST00000452200(transcript)|ensembl:ENST00000677913(transcript)|ensembl:ENST00000678761(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051604"(protein maturation)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P10809|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|rcsb pdb:7AZP|reactome:R-HSA-1268020|reactome:R-HSA-8869496|dip:DIP-58N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:syB2vt66Cpr2mJROfbxoPevoiRE9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q92569 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-79893|intact:EBI-28975437|ensembl:ENSP00000262741|ensembl:ENSP00000361075|ensembl:ENSP00000412546|uniprotkb:O60482|uniprotkb:Q5T4P2|uniprotkb:B2R9C1|uniprotkb:Q5T4P1|uniprotkb:D3DQ12 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:p55g_human(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma(gene name synonym)|uniprotkb:PIK3R3(gene name)|psi-mi:PIK3R3(display_short)|uniprotkb:p55PIK(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9670439|ensembl:ENSG00000117461(gene)|ensembl:ENST00000262741(transcript)|ensembl:ENST00000372006(transcript)|ensembl:ENST00000420542(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|interpro:IPR000980(SH2 motif)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR036860|mint:Q92569|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-2219530|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-512988|reactome:R-HSA-6811558|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|reactome:R-HSA-8853659|reactome:R-HSA-9009391|refseq:NP_001107644.1|refseq:NP_003620.3|ensembl:ENSP00000262741|ensembl:ENSP00000361075|ensembl:ENSP00000412546|ensembl:ENST00000423209|ensembl:ENSP00000391431|dip:DIP-30925N|refseq:NP_001290358.1|refseq:XP_016858103.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:oIVTuGRhg/Kn3h+Br1EfiAtiAQQ9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P14174 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-372712|uniprotkb:A5Z1R8|uniprotkb:B2R4S3|uniprotkb:Q6FHV0|uniprotkb:Q2V4Y5|ensembl:ENSP00000215754|ensembl:ENSP00000482779 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:mif_human(display_long)|uniprotkb:MIF(gene name)|psi-mi:MIF(display_short)|uniprotkb:MMIF(gene name synonym)|uniprotkb:GLIF(gene name synonym)|uniprotkb:Phenylpyruvate tautomerase(gene name synonym)|uniprotkb:Glycosylation-inhibiting factor(gene name synonym)|uniprotkb:L-dopachrome tautomerase(gene name synonym)|uniprotkb:L-dopachrome isomerase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_002406.1|ensembl:ENST00000215754(transcript)|ensembl:ENST00000613839(transcript)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004167"(dopachrome isomerase activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|ensembl:ENSG00000276701(gene)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0010760"(negative regulation of macrophage chemotaxis)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031982"(vesicle)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|ensembl:ENSG00000240972(gene)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045087"(innate immune response)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050178"(phenylpyruvate tautomerase activity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001398(Macrophage migration inhibitory factor)|interpro:IPR014347(Tautomerase)|interpro:IPR019829|mint:P14174|rcsb pdb:1CGQ|rcsb pdb:1GCZ|rcsb pdb:1GD0|rcsb pdb:1GIF|rcsb pdb:1LJT|rcsb pdb:1MIF|rcsb pdb:1P1G|rcsb pdb:2OOH|rcsb pdb:2OOW|rcsb pdb:2OOZ|rcsb pdb:3B9S|rcsb pdb:3CE4|rcsb pdb:3DJH|rcsb pdb:3DJI|rcsb pdb:3HOF|rcsb pdb:3IJG|rcsb pdb:3IJJ|rcsb pdb:3JSF|rcsb pdb:3JSG|rcsb pdb:3JTU|rcsb pdb:3L5P|rcsb pdb:3L5R|rcsb pdb:3L5S|rcsb pdb:3L5T|rcsb pdb:3L5U|rcsb pdb:3L5V|rcsb pdb:3SMB|rcsb pdb:3SMC|rcsb pdb:3U18|rcsb pdb:3WNR|rcsb pdb:3WNS|rcsb pdb:3WNT|rcsb pdb:4ETG|rcsb pdb:4EUI|rcsb pdb:4EVG|rcsb pdb:4F2K|rcsb pdb:4GRN|rcsb pdb:4GRO|rcsb pdb:4GRP|rcsb pdb:4GRQ|rcsb pdb:4GRR|rcsb pdb:4GRU|rcsb pdb:4GUM|rcsb pdb:4K9G|rcsb pdb:4OSF|rcsb pdb:4OYQ|rcsb pdb:4P01|rcsb pdb:4P0H|rcsb pdb:4PKK|rcsb pdb:4PKZ|rcsb pdb:4PLU|rcsb pdb:4TRF|rcsb pdb:4TRU|rcsb pdb:4WR8|rcsb pdb:4WRB|rcsb pdb:4XX7|rcsb pdb:4XX8|rcsb pdb:4Z15|rcsb pdb:4Z1T|rcsb pdb:4Z1U|rcsb pdb:5B4O|rcsb pdb:5BS9|rcsb pdb:5BSC|rcsb pdb:5BSI|rcsb pdb:5BSJ|rcsb pdb:5EIZ|rcsb pdb:5HVS|rcsb pdb:5HVT|rcsb pdb:5HVV|rcsb pdb:5J7P|rcsb pdb:5J7Q|rcsb pdb:5UMJ|rcsb pdb:5UMK|rcsb pdb:5UZY|rcsb pdb:5V70|rcsb pdb:5V73|rcsb pdb:5XEJ|rcsb pdb:1CA7|rcsb pdb:6B1C|rcsb pdb:6B1K|rcsb pdb:6B2C|rcsb pdb:6BG6|rcsb pdb:6BG7|rcsb pdb:6CB5|rcsb pdb:6CBF|rcsb pdb:6CBG|rcsb pdb:6FVE|rcsb pdb:6FVH|rcsb pdb:6OY8|rcsb pdb:6OYB|rcsb pdb:6OYE|rcsb pdb:6OYG|rcsb pdb:6PEG|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-8950505|rcsb pdb:6CBH|dip:DIP-31137N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:Vk+Sfaz5c59y8dKKJ4Qn+7fjwvQ9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:O00459 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-346930|uniprotkb:Q5EAT5|uniprotkb:Q9UPH9|intact:EBI-28974273|ensembl:ENSP00000222254 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:p85b_human(display_long)|uniprotkb:PIK3R2(gene name)|psi-mi:PIK3R2(display_short)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSP00000222254|refseq:NP_005018.1|dip:DIP-31811N|ensembl:ENSG00000105647(gene)|ensembl:ENST00000222254(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|rcsb pdb:6OX7|rcsb pdb:6U28|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-186763|reactome:R-HSA-198203|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|mint:O00459|rcsb pdb:2KT1|rcsb pdb:2XS6|rcsb pdb:3MTT|rcsb pdb:3O5Z|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-210993|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9013409 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:Ij0WS0eKPwShgFWQc7OEss7AcAU9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P22626 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P42338 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-2609540|uniprotkb:D3DNF0|uniprotkb:Q24JU2|ensembl:ENSP00000289153|ensembl:ENSP00000418143|ensembl:ENSP00000501150 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pk3cb_human(display_long)|uniprotkb:PIK3CB(gene name)|psi-mi:PIK3CB(display_short)|uniprotkb:PIK3C1(gene name synonym)|uniprotkb:Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_006210.1|refseq:XP_011511197.1|refseq:XP_005247587.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0030168"(platelet activation)|go:"GO:0030496"(midbody)|go:"GO:0033031"(positive regulation of neutrophil apoptotic process)|go:"GO:0035004"(phosphatidylinositol 3-kinase activity)|go:"GO:0035005"(1-phosphatidylinositol-4-phosphate 3-kinase activity)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046934"(phosphatidylinositol-4,5-bisphosphate 3-kinase activity)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0070527"(platelet aggregation)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR000341(Phosphoinositide 3-kinase, ras-binding)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR003113(Phosphatidylinositol 3-kinase, p85-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR029071|interpro:IPR035892|interpro:IPR036940|interpro:IPR037702|interpro:IPR042236|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1660499|reactome:R-HSA-186763|reactome:R-HSA-198203|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8853659|reactome:R-HSA-9027276|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9673767|reactome:R-HSA-9673770|ensembl:ENSG00000051382(gene)|ensembl:ENST00000289153(transcript)|ensembl:ENST00000477593(transcript)|ensembl:ENST00000674063(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001952"(regulation of cell-matrix adhesion)|go:"GO:0002931"(response to ischemia)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_006713722.1|refseq:XP_016862108.1|dip:DIP-44775N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:Nga6TlSCXWs2NVRR5XfxvnLfWUk9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P68104 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q99729 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P68366 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-351772|uniprotkb:A8MUB1|uniprotkb:P05215|ensembl:ENSP00000248437|uniprotkb:B3KNQ6|intact:EBI-11134566 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:tba4a_human(display_long)|uniprotkb:TUBA4A(gene name)|psi-mi:TUBA4A(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Testis-specific alpha-tubulin(gene name synonym)|uniprotkb:Tubulin H2-alpha(gene name synonym)|uniprotkb:TUBA1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_005991.1|ensembl:ENSG00000127824(gene)|ensembl:ENST00000248437(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68366|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001265481.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P63104 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P35579 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-350338|uniprotkb:O60805|ensembl:ENSP00000216181|uniprotkb:Q86T83|intact:EBI-1054343|uniprotkb:A8K6E4|uniprotkb:Q60FE2 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_002464.1|ensembl:ENSG00000100345(gene)|ensembl:ENST00000216181(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|refseq:XP_011528499.1|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0097513"(myosin II filament)|go:"GO:1903919"(negative regulation of actin filament severing)|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:O00159 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-350423|uniprotkb:Q6NVJ7|intact:EBI-1045431|uniprotkb:Q86Y95|uniprotkb:Q4LE56|ensembl:ENSP00000496954 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:myo1c_human(display_long)|uniprotkb:MYO1C(gene name)|psi-mi:MYO1C(display_short)|uniprotkb:Myosin I beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0006605"(protein targeting)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0005829"(cytosol)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0038089"(positive regulation of cell migration by vascular endothelial growth factor signaling pathway)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|refseq:NP_001074248.1|refseq:NP_001074419.1|refseq:NP_203693.3|ensembl:ENSG00000197879(gene)|ensembl:ENST00000648651(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|interpro:IPR036961|mint:O00159|rcsb pdb:4BYF|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-5250924|reactome:R-HSA-9662360|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|reactome:R-HSA-9662361|reactome:R-HSA-9664422|dip:DIP-33109N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:g6wQN0OVKjd3T1kOebWFcqWNzNA9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P05388 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-354101|uniprotkb:Q9BVK4|intact:EBI-8012155|intact:MINT-8395053|uniprotkb:Q3B7A4|ensembl:ENSP00000339027|ensembl:ENSP00000376299|ensembl:ENSP00000449328 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rla0_human(display_long)|uniprotkb:RPLP0(gene name)|psi-mi:RPLP0(display_short)|uniprotkb:60S ribosomal protein L10E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL10(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6156949|imex:IM-17331-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_000993.1|refseq:NP_444505.1|ensembl:ENSG00000089157(gene)|ensembl:ENST00000228306(transcript)|ensembl:ENST00000392514(transcript)|ensembl:ENST00000551150(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0098794"(postsynapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR030670|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:P05388|rcsb pdb:4V6W|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8950505|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:xv3QHqnXxvCd3BOIeHVkqEnSNNk9606 intact-crc:75E7EAA95B4FA671|rigid:lO7CVL5jta4xNGMzFiFkjpkx3Oc false mutation:38-38,41-41|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99AU3 uniprotkb:P22626 intact:EBI-6150155 intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61 psi-mi:ns1_i18a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:88776(i18a0)|taxid:88776("Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157083|imex:IM-17331-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61813N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2N74|rcsb pdb:5UL6|rcsb pdb:6ATV|rcsb pdb:6DGK|rcsb pdb:6NU0|rcsb pdb:6OX7|rcsb pdb:6U28 go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2018/04/06 rogid:A0wZuIW8uezDFqFkBcQ7yDrVj6Q88776 rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606 intact-crc:3B5318C2D520ED0F false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99AU3 intact:EBI-6147672 intact:EBI-6150155 - psi-mi:ns1_i18a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:p0c7m2_human(display_short)|psi-mi:EBI-6147672(display_long) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:88776(i18a0)|taxid:88776("Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157083|imex:IM-17331-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61813N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2N74|rcsb pdb:5UL6|rcsb pdb:6ATV|rcsb pdb:6DGK|rcsb pdb:6NU0|rcsb pdb:6OX7|rcsb pdb:6U28 uniprotkb:P0C7M2(uniprot-removed-ac) - - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2018/04/06 rogid:A0wZuIW8uezDFqFkBcQ7yDrVj6Q88776 - intact-crc:3B5318C2D520ED0F false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99AU3 uniprotkb:Q5JVF3 intact:EBI-6150155 intact:EBI-1051701|uniprotkb:A6NK09|uniprotkb:Q3ZCX1|uniprotkb:Q5TC57|uniprotkb:Q5TC58|uniprotkb:Q9H7K1|uniprotkb:Q9HBZ7|uniprotkb:Q9NUK6|uniprotkb:Q9NVY1|uniprotkb:Q9NW44|uniprotkb:Q9NWH3|ensembl:ENSP00000337405|ensembl:ENSP00000364626|ensembl:ENSP00000364628 psi-mi:ns1_i18a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pcid2_human(display_long)|uniprotkb:CSN12-like protein(gene name synonym)|uniprotkb:PCID2(gene name)|psi-mi:PCID2(display_short)|uniprotkb:HT004(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:88776(i18a0)|taxid:88776("Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157083|imex:IM-17331-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61813N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2N74|rcsb pdb:5UL6|rcsb pdb:6ATV|rcsb pdb:6DGK|rcsb pdb:6NU0|rcsb pdb:6OX7|rcsb pdb:6U28 refseq:NP_001120674.1|refseq:NP_001120675.1|refseq:NP_060856.2|refseq:NP_001245142.1|refseq:NP_001307584.1|refseq:NP_001307585.1|refseq:NP_001307586.1|refseq:NP_001307589.1|ensembl:ENSG00000126226(gene)|ensembl:ENST00000337344(transcript)|ensembl:ENST00000375477(transcript)|ensembl:ENST00000375479(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048536"(spleen development)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:2000117"(negative regulation of cysteine-type endopeptidase activity)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|rcsb pdb:3T5X|refseq:XP_016876153.1|dip:DIP-50497N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2018/04/06 rogid:A0wZuIW8uezDFqFkBcQ7yDrVj6Q88776 rogid:jFHv4Xifu2Qw/CzD5SKl3PgJpgE9606 intact-crc:3B5318C2D520ED0F false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99AU3 uniprotkb:Q12905 intact:EBI-6150155 intact:EBI-357925|uniprotkb:A6NDB0|uniprotkb:Q5SR10|uniprotkb:Q5SR11|uniprotkb:Q7L7R3|uniprotkb:Q9BWD4|uniprotkb:Q9P1N0|uniprotkb:B2R8G7|ensembl:ENSP00000355011 psi-mi:ns1_i18a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ilf2_human(display_long)|uniprotkb:PRO3063(orf name)|uniprotkb:NF45(gene name synonym)|uniprotkb:ILF2(gene name)|psi-mi:ILF2(display_short)|uniprotkb:Nuclear factor of activated T-cells 45 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:88776(i18a0)|taxid:88776("Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157083|imex:IM-17331-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61813N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2N74|rcsb pdb:5UL6|rcsb pdb:6ATV|rcsb pdb:6DGK|rcsb pdb:6NU0|rcsb pdb:6OX7|rcsb pdb:6U28 refseq:NP_004506.2|refseq:NP_001254738.1|ensembl:ENSG00000143621(gene)|ensembl:ENST00000361891(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR043519|mint:Q12905|reactome:R-HSA-6798695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2018/04/06 rogid:A0wZuIW8uezDFqFkBcQ7yDrVj6Q88776 rogid:HwUDuY6Ev7csoTThxZCW8nJT88o9606 intact-crc:3B5318C2D520ED0F false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99AU3 uniprotkb:Q00839 intact:EBI-6150155 intact:EBI-351126|uniprotkb:O75507|uniprotkb:Q8N174|uniprotkb:Q96HY9|uniprotkb:Q9BQ09|ensembl:ENSP00000491215 psi-mi:ns1_i18a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpu_human(display_long)|uniprotkb:HNRNPU(gene name)|psi-mi:HNRNPU(display_short)|uniprotkb:SAFA(gene name synonym)|uniprotkb:U21.1(gene name synonym)|uniprotkb:HNRPU(gene name synonym)|uniprotkb:p120(gene name synonym)|uniprotkb:pp120(gene name synonym)|uniprotkb:C1orf199(gene name synonym)|uniprotkb:GRIP120(gene name synonym)|uniprotkb:Nuclear p120 ribonucleoprotein(gene name synonym)|uniprotkb:Scaffold-attachment factor A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:88776(i18a0)|taxid:88776("Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157083|imex:IM-17331-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61813N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2N74|rcsb pdb:5UL6|rcsb pdb:6ATV|rcsb pdb:6DGK|rcsb pdb:6NU0|rcsb pdb:6OX7|rcsb pdb:6U28 refseq:NP_004492.2|refseq:NP_114032.2|ensembl:ENSG00000153187(gene)|ensembl:ENST00000640218(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:1990498"(mitotic spindle microtubule)|go:"GO:0098577"(inactive sex chromosome)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR026745|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q00839|rcsb pdb:1ZRJ|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990280"(RNA localization to chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006396"(RNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008143"("poly(A) binding")|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0017130"("poly(C) RNA binding")|go:"GO:0030496"(midbody)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|refseq:XP_016856604.1|refseq:XP_016856605.1|refseq:XP_016856606.1|dip:DIP-684N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2018/04/06 rogid:A0wZuIW8uezDFqFkBcQ7yDrVj6Q88776 rogid:n73PY0Vis+D5Iq0q77h5Ck2V4789606 intact-crc:3B5318C2D520ED0F false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99AU3 uniprotkb:O60506 intact:EBI-6150155 intact:EBI-1024357|uniprotkb:Q53H05|uniprotkb:Q5TCG2|uniprotkb:Q8IW78|uniprotkb:Q8N599|uniprotkb:Q96LC1|uniprotkb:Q96LC2|uniprotkb:Q9Y583|uniprotkb:Q5TCG3|uniprotkb:E1P501|uniprotkb:E1P502|ensembl:ENSP00000358635|ensembl:ENSP00000503783|ensembl:ENSP00000504706 psi-mi:ns1_i18a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpq_human(display_long)|uniprotkb:Synaptotagmin-binding, cytoplasmic RNA-interacting protein(gene name synonym)|uniprotkb:Glycine- and tyrosine-rich RNA-binding protein(gene name synonym)|uniprotkb:NS1-associated protein 1(gene name synonym)|uniprotkb:SYNCRIP(gene name)|psi-mi:SYNCRIP(display_short)|uniprotkb:HNRPQ(gene name synonym)|uniprotkb:NSAP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:88776(i18a0)|taxid:88776("Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157083|imex:IM-17331-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61813N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2N74|rcsb pdb:5UL6|rcsb pdb:6ATV|rcsb pdb:6DGK|rcsb pdb:6NU0|rcsb pdb:6OX7|rcsb pdb:6U28 refseq:NP_001153145.1|refseq:NP_001153146.1|refseq:NP_001153147.1|refseq:NP_001240700.1|refseq:NP_001153148.1|refseq:NP_001153149.1|refseq:NP_006363.4|ensembl:ENSG00000135316(gene)|ensembl:ENST00000369622(transcript)|ensembl:ENST00000676688(transcript)|ensembl:ENST00000678355(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034544|interpro:IPR034548|interpro:IPR035979|interpro:IPR041337|mint:O60506|rcsb pdb:2DGU|rcsb pdb:2MXT|rcsb pdb:2NBB|rcsb pdb:6KOR|refseq:XP_016865667.1|refseq:XP_005248694.1|dip:DIP-35540N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2018/04/06 rogid:A0wZuIW8uezDFqFkBcQ7yDrVj6Q88776 rogid:2rDkXIp/wWzTOoVtN7Bd3uqZo689606 intact-crc:3B5318C2D520ED0F false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99AU3 uniprotkb:Q9NZI8 intact:EBI-6150155 intact:EBI-1053892|uniprotkb:C9JT33|ensembl:ENSP00000290341 psi-mi:ns1_i18a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:if2b1_human(display_long)|uniprotkb:ZBP1(gene name synonym)|uniprotkb:IGF-II mRNA-binding protein 1(gene name synonym)|uniprotkb:Coding region determinant-binding protein(gene name synonym)|uniprotkb:VICKZ family member 1(gene name synonym)|uniprotkb:IGF2BP1(gene name)|psi-mi:IGF2BP1(display_short)|uniprotkb:Zipcode-binding protein 1(gene name synonym)|uniprotkb:CRDBP(gene name synonym)|uniprotkb:VICKZ1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:88776(i18a0)|taxid:88776("Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157083|imex:IM-17331-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61813N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2N74|rcsb pdb:5UL6|rcsb pdb:6ATV|rcsb pdb:6DGK|rcsb pdb:6NU0|rcsb pdb:6OX7|rcsb pdb:6U28 refseq:NP_006537.3|refseq:NP_001153895.1|ensembl:ENSG00000159217(gene)|ensembl:ENST00000290341(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007399"(nervous system development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010610"(regulation of mRNA stability involved in response to stress)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022013"(pallium cell proliferation in forebrain)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0140059"(dendrite arborization)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034837|interpro:IPR034842|interpro:IPR035979|interpro:IPR036612|mint:Q9NZI8|rcsb pdb:3KRM|rcsb pdb:6QEY|reactome:R-HSA-428359|reactome:R-HSA-5687128|dip:DIP-38139N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2018/04/06 rogid:A0wZuIW8uezDFqFkBcQ7yDrVj6Q88776 rogid:3Ps/PWWYr0WpYcx3G/AOiQEj+vc9606 intact-crc:3B5318C2D520ED0F false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99AU3 uniprotkb:P14866 intact:EBI-6150155 intact:EBI-719024|uniprotkb:Q9H3P3|uniprotkb:A6ND69|uniprotkb:A6NIT8|ensembl:ENSP00000221419|ensembl:ENSP00000489021 psi-mi:ns1_i18a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpl_human(display_long)|uniprotkb:HNRPL(gene name synonym)|uniprotkb:HNRNPL(gene name)|psi-mi:HNRNPL(display_short)|uniprotkb:P/OKcl.14(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:88776(i18a0)|taxid:88776("Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157083|imex:IM-17331-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61813N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2N74|rcsb pdb:5UL6|rcsb pdb:6ATV|rcsb pdb:6DGK|rcsb pdb:6NU0|rcsb pdb:6OX7|rcsb pdb:6U28 refseq:NP_001005335.1|refseq:NP_001524.2|refseq:XP_011525191.1|ensembl:ENSG00000282947(gene)|ensembl:ENST00000221419(transcript)|ensembl:ENST00000634753(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097157"(pre-mRNA intronic binding)|ensembl:ENSG00000104824(gene)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034816|interpro:IPR034817|interpro:IPR035005|interpro:IPR035008|interpro:IPR035979|mint:P14866|rcsb pdb:3R27|rcsb pdb:3TO8|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:1990904"(ribonucleoprotein complex)|dip:DIP-36355N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2018/04/06 rogid:A0wZuIW8uezDFqFkBcQ7yDrVj6Q88776 rogid:vOfznm03e6Ottg6BptYHmR9qJEc9606 intact-crc:3B5318C2D520ED0F false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99AU3 uniprotkb:Q13310 intact:EBI-6150155 intact:EBI-372844|uniprotkb:Q6P0N3|uniprotkb:B1ANQ8|ensembl:ENSP00000361948|intact:EBI-877641|uniprotkb:Q4VC03 psi-mi:ns1_i18a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pabp4_human(display_long)|uniprotkb:PABPC4(gene name)|psi-mi:PABPC4(display_short)|uniprotkb:APP1(gene name synonym)|uniprotkb:PABP4(gene name synonym)|uniprotkb:"Inducible poly(A)-binding protein"(gene name synonym)|uniprotkb:Activated-platelet protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:88776(i18a0)|taxid:88776("Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157083|imex:IM-17331-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61813N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2N74|rcsb pdb:5UL6|rcsb pdb:6ATV|rcsb pdb:6DGK|rcsb pdb:6NU0|rcsb pdb:6OX7|rcsb pdb:6U28 refseq:NP_001129126.1|refseq:NP_003810.1|ensembl:ENSG00000090621(gene)|ensembl:ENST00000372857(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006412"(translation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0061515"(myeloid cell development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:Q13310|refseq:NP_001129125.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2018/04/06 rogid:A0wZuIW8uezDFqFkBcQ7yDrVj6Q88776 rogid:u1qCM3o5X7jLIa1vyqFCIH7v01w9606 intact-crc:3B5318C2D520ED0F false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99AU3 uniprotkb:O00459 intact:EBI-6150155 intact:EBI-346930|uniprotkb:Q5EAT5|uniprotkb:Q9UPH9|intact:EBI-28974273|ensembl:ENSP00000222254 psi-mi:ns1_i18a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:p85b_human(display_long)|uniprotkb:PIK3R2(gene name)|psi-mi:PIK3R2(display_short)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:88776(i18a0)|taxid:88776("Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157083|imex:IM-17331-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61813N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2N74|rcsb pdb:5UL6|rcsb pdb:6ATV|rcsb pdb:6DGK|rcsb pdb:6NU0|rcsb pdb:6OX7|rcsb pdb:6U28 ensembl:ENSP00000222254|refseq:NP_005018.1|dip:DIP-31811N|ensembl:ENSG00000105647(gene)|ensembl:ENST00000222254(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|rcsb pdb:6OX7|rcsb pdb:6U28|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-186763|reactome:R-HSA-198203|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|mint:O00459|rcsb pdb:2KT1|rcsb pdb:2XS6|rcsb pdb:3MTT|rcsb pdb:3O5Z|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-210993|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9013409 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2018/04/06 rogid:A0wZuIW8uezDFqFkBcQ7yDrVj6Q88776 rogid:Ij0WS0eKPwShgFWQc7OEss7AcAU9606 intact-crc:3B5318C2D520ED0F false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99AU3 uniprotkb:P09651 intact:EBI-6150155 intact:EBI-352662|uniprotkb:Q3MIB7|uniprotkb:Q6PJZ7|ensembl:ENSP00000341826|ensembl:ENSP00000503610|uniprotkb:A8K4Z8|intact:EBI-2556572 psi-mi:ns1_i18a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:roa1_human(display_long)|uniprotkb:HNRNPA1(gene name)|psi-mi:HNRNPA1(display_short)|uniprotkb:HNRPA1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:Single-strand RNA-binding protein(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:88776(i18a0)|taxid:88776("Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157083|imex:IM-17331-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61813N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2N74|rcsb pdb:5UL6|rcsb pdb:6ATV|rcsb pdb:6DGK|rcsb pdb:6NU0|rcsb pdb:6OX7|rcsb pdb:6U28 refseq:NP_002127.1|refseq:NP_112420.1|ensembl:ENSG00000135486(gene)|ensembl:ENST00000340913(transcript)|ensembl:ENST00000677210(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|rcsb pdb:2LYV|rcsb pdb:2UP1|rcsb pdb:4YOE|rcsb pdb:5MPG|rcsb pdb:5MPL|rcsb pdb:5ZGD|rcsb pdb:5ZGL|rcsb pdb:6BXX|rcsb pdb:6DCL|rcsb pdb:6J60|rcsb pdb:7BX7|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035198"(miRNA binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051170"(import into nucleus)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR034845|interpro:IPR035979|mint:P09651|rcsb pdb:1HA1|rcsb pdb:1L3K|rcsb pdb:1PGZ|rcsb pdb:1PO6|rcsb pdb:1U1K|rcsb pdb:1U1L|rcsb pdb:1U1M|rcsb pdb:1U1N|rcsb pdb:1U1O|rcsb pdb:1U1P|rcsb pdb:1U1Q|rcsb pdb:1U1R|rcsb pdb:1UP1|rcsb pdb:2H4M|refseq:XP_005268883.1|dip:DIP-29338N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2018/04/06 rogid:A0wZuIW8uezDFqFkBcQ7yDrVj6Q88776 rogid:ECXjsLRVtNc/aOw90tEFxowHc6c9606 intact-crc:3B5318C2D520ED0F false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99AU3 uniprotkb:P07437 intact:EBI-6150155 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:ns1_i18a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:88776(i18a0)|taxid:88776("Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157083|imex:IM-17331-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61813N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2N74|rcsb pdb:5UL6|rcsb pdb:6ATV|rcsb pdb:6DGK|rcsb pdb:6NU0|rcsb pdb:6OX7|rcsb pdb:6U28 refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2018/04/06 rogid:A0wZuIW8uezDFqFkBcQ7yDrVj6Q88776 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:3B5318C2D520ED0F false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99AU3 uniprotkb:Q9NPA8 intact:EBI-6150155 intact:EBI-719226|uniprotkb:B2RE52|intact:EBI-10972054|uniprotkb:G3V117|ensembl:ENSP00000429986 psi-mi:ns1_i18a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:eny2_human(display_long)|uniprotkb:Enhancer of yellow 2 transcription factor homolog(gene name synonym)|uniprotkb:DC6(orf name)|uniprotkb:ENY2(gene name)|psi-mi:ENY2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:88776(i18a0)|taxid:88776("Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157083|imex:IM-17331-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61813N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2N74|rcsb pdb:5UL6|rcsb pdb:6ATV|rcsb pdb:6DGK|rcsb pdb:6NU0|rcsb pdb:6OX7|rcsb pdb:6U28 refseq:NP_001180486.1|refseq:NP_064574.1|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071819"(DUBm complex)|interpro:IPR018783|interpro:IPR038212|mint:Q9NPA8|rcsb pdb:4DHX|go:"GO:0030374"(nuclear receptor coactivator activity)|reactome:R-HSA-3214847|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0015031"(protein transport)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|ensembl:ENSG00000120533(gene)|ensembl:ENST00000521688(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2018/04/06 rogid:A0wZuIW8uezDFqFkBcQ7yDrVj6Q88776 rogid:CJmjqxLqgpxrqtvVVFcgxW5nloE9606 intact-crc:3B5318C2D520ED0F false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99AU3 uniprotkb:O43390 intact:EBI-6150155 intact:EBI-713419|uniprotkb:S4R3J4|uniprotkb:Q5TEH1|ensembl:ENSP00000304405|ensembl:ENSP00000363741|ensembl:ENSP00000489252|ensembl:ENSP00000489371|uniprotkb:Q9BV64|uniprotkb:Q2L7G6 psi-mi:ns1_i18a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpr_human(display_long)|uniprotkb:HNRPR(gene name synonym)|uniprotkb:HNRNPR(gene name)|psi-mi:HNRNPR(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:88776(i18a0)|taxid:88776("Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157083|imex:IM-17331-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61813N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2N74|rcsb pdb:5UL6|rcsb pdb:6ATV|rcsb pdb:6DGK|rcsb pdb:6NU0|rcsb pdb:6OX7|rcsb pdb:6U28 refseq:NP_001095868.1|refseq:XP_005245768.1|ensembl:ENSG00000125944(gene)|ensembl:ENSG00000282958(gene)|ensembl:ENST00000302271(transcript)|ensembl:ENST00000374612(transcript)|ensembl:ENST00000634263(transcript)|ensembl:ENST00000634766(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043679"(axon terminus)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034411|interpro:IPR035979|mint:O43390|rcsb pdb:2DK2|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR041337|refseq:NP_005817.1|refseq:XP_011538773.1|refseq:NP_001284549.1|refseq:XP_016855497.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2018/04/06 rogid:A0wZuIW8uezDFqFkBcQ7yDrVj6Q88776 rogid:UiOaRbnMd1S2FthR4RWltyq6xT49606 intact-crc:3B5318C2D520ED0F false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99AU3 uniprotkb:P55265 intact:EBI-6150155 intact:EBI-2462104|uniprotkb:B1AQR0|uniprotkb:O15223|uniprotkb:O43859|uniprotkb:O43860|uniprotkb:Q9BYM3|uniprotkb:Q9BYM4|uniprotkb:B1AQQ9|uniprotkb:D3DV76|ensembl:ENSP00000357459 psi-mi:ns1_i18a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:dsrad_human(display_long)|uniprotkb:ADAR(gene name)|psi-mi:ADAR(display_short)|uniprotkb:ADAR1(gene name synonym)|uniprotkb:DSRAD(gene name synonym)|uniprotkb:G1P1(gene name synonym)|uniprotkb:IFI4(gene name synonym)|uniprotkb:136 kDa double-stranded RNA-binding protein(gene name synonym)|uniprotkb:K88DSRBP(gene name synonym)|uniprotkb:Interferon-inducible protein 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:88776(i18a0)|taxid:88776("Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157083|imex:IM-17331-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61813N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2N74|rcsb pdb:5UL6|rcsb pdb:6ATV|rcsb pdb:6DGK|rcsb pdb:6NU0|rcsb pdb:6OX7|rcsb pdb:6U28 refseq:NP_001020278.1|refseq:NP_001102.2|refseq:NP_001180424.1|refseq:NP_056655.2|refseq:NP_056656.2|refseq:XP_006711174.1|refseq:XP_006711175.1|refseq:XP_006711176.1|dip:DIP-29310N|ensembl:ENSG00000160710(gene)|ensembl:ENST00000368474(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002566"(somatic diversification of immune receptors via somatic mutation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0008251"(tRNA-specific adenosine deaminase activity)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016553"(base conversion or substitution editing)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900369"(negative regulation of RNA interference)|interpro:IPR002466(Adenosine deaminase/editase)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371|interpro:IPR044456|interpro:IPR044457|mint:P55265|rcsb pdb:1QBJ|rcsb pdb:1QGP|rcsb pdb:1XMK|rcsb pdb:2ACJ|rcsb pdb:2GXB|rcsb pdb:2L54|rcsb pdb:2MDR|rcsb pdb:3F21|rcsb pdb:3F22|rcsb pdb:3F23|rcsb pdb:3IRQ|rcsb pdb:3IRR|rcsb pdb:5ZU1|rcsb pdb:5ZUO|rcsb pdb:5ZUP|rcsb pdb:7C0I|reactome:R-HSA-75102|reactome:R-HSA-77042|reactome:R-HSA-909733|go:"GO:0051607"(defense response to virus) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2018/04/06 rogid:A0wZuIW8uezDFqFkBcQ7yDrVj6Q88776 rogid:rP/Yr/h8WLSFNdIuqWnYtZjZ9qI9606 intact-crc:3B5318C2D520ED0F false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99AU3 uniprotkb:P07910 intact:EBI-6150155 intact:EBI-357966|uniprotkb:P22628|uniprotkb:Q53EX2|uniprotkb:Q59FD3|uniprotkb:Q5FWE8|uniprotkb:Q86SF8|uniprotkb:Q86U45|uniprotkb:Q96HK7|uniprotkb:Q96HM4|uniprotkb:Q96IY5|uniprotkb:Q9BTS3|uniprotkb:D3DS19|uniprotkb:D3DS22|intact:EBI-28976506|ensembl:ENSP00000404848|ensembl:ENSP00000451291|ensembl:ENSP00000452276 psi-mi:ns1_i18a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpc_human(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:88776(i18a0)|taxid:88776("Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157083|imex:IM-17331-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61813N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2N74|rcsb pdb:5UL6|rcsb pdb:6ATV|rcsb pdb:6DGK|rcsb pdb:6NU0|rcsb pdb:6OX7|rcsb pdb:6U28 refseq:NP_001070910.1|refseq:NP_001070911.1|refseq:NP_004491.2|refseq:NP_112604.2|ensembl:ENSP00000404848|ensembl:ENST00000430246|ensembl:ENSP00000442816|ensembl:ENST00000553300|ensembl:ENSP00000450544|ensembl:ENSP00000451291|ensembl:ENST00000554969|ensembl:ENSP00000452276|ensembl:ENSP00000450725|ensembl:ENST00000555883|ensembl:ENSP00000450629|ensembl:ENST00000556628|ensembl:ENSP00000451652|ensembl:ENST00000556897|ensembl:ENSP00000451176|refseq:XP_011535010.1|refseq:XP_011535011.1|refseq:XP_011535012.1|refseq:XP_011535013.1|refseq:XP_011535014.1|refseq:XP_016876741.1|refseq:XP_016876742.1|dip:DIP-29854N|refseq:XP_006720188.1|ensembl:ENSG00000092199(gene)|ensembl:ENST00000420743(transcript)|ensembl:ENST00000554455(transcript)|ensembl:ENST00000557201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979|mint:P07910|rcsb pdb:1TXP|rcsb pdb:1WF2|rcsb pdb:2MXY|rcsb pdb:2MZ1|rcsb pdb:3LN4|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2018/04/06 rogid:A0wZuIW8uezDFqFkBcQ7yDrVj6Q88776 rogid:Fj5tiH0wrNUjTnsURIg8dB8laMg9606 intact-crc:3B5318C2D520ED0F false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99AU3 uniprotkb:P11940 intact:EBI-6150155 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:ns1_i18a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:88776(i18a0)|taxid:88776("Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157083|imex:IM-17331-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61813N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2N74|rcsb pdb:5UL6|rcsb pdb:6ATV|rcsb pdb:6DGK|rcsb pdb:6NU0|rcsb pdb:6OX7|rcsb pdb:6U28 interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2018/04/06 rogid:A0wZuIW8uezDFqFkBcQ7yDrVj6Q88776 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 intact-crc:3B5318C2D520ED0F false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99AU3 uniprotkb:Q8N163 intact:EBI-6150155 intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|ensembl:ENSP00000310670|ensembl:ENSP00000373930|uniprotkb:B2RB79|uniprotkb:D3DSR6 psi-mi:ns1_i18a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:88776(i18a0)|taxid:88776("Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157083|imex:IM-17331-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61813N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2N74|rcsb pdb:5UL6|rcsb pdb:6ATV|rcsb pdb:6DGK|rcsb pdb:6NU0|rcsb pdb:6OX7|rcsb pdb:6U28 refseq:NP_066997.3|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|interpro:IPR028811|mint:Q8N163|reactome:R-HSA-3371453|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|dip:DIP-38122N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2018/04/06 rogid:A0wZuIW8uezDFqFkBcQ7yDrVj6Q88776 rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606 intact-crc:3B5318C2D520ED0F false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99AU3 uniprotkb:Q08211 intact:EBI-6150155 intact:EBI-352022|intact:EBI-1058470|uniprotkb:Q5VY62|uniprotkb:Q6PD69|uniprotkb:Q99556|uniprotkb:B2RNV4|uniprotkb:Q05CI5|uniprotkb:Q12803|uniprotkb:Q32Q22|ensembl:ENSP00000356520 psi-mi:ns1_i18a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:dhx9_human(display_long)|uniprotkb:DHX9(gene name)|psi-mi:DHX9(display_short)|uniprotkb:DDX9(gene name synonym)|uniprotkb:NDH2(gene name synonym)|uniprotkb:DExH-box helicase 9(gene name synonym)|uniprotkb:RNA helicase A(gene name synonym)|uniprotkb:LKP(gene name synonym)|uniprotkb:Nuclear DNA helicase II(gene name synonym)|uniprotkb:DEAH box protein 9(gene name synonym)|uniprotkb:Leukophysin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:88776(i18a0)|taxid:88776("Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157083|imex:IM-17331-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61813N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2N74|rcsb pdb:5UL6|rcsb pdb:6ATV|rcsb pdb:6DGK|rcsb pdb:6NU0|rcsb pdb:6OX7|rcsb pdb:6U28 refseq:NP_001348.2|dip:DIP-31504N|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033679"(3'-5' DNA/RNA helicase activity)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045142"(triplex DNA binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0097165"(nuclear stress granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1905172"(RISC complex binding)|go:"GO:1905538"(polysome binding)|go:"GO:1905698"(positive regulation of polysome binding)|go:"GO:1990518"(single-stranded 3'-5' DNA helicase activity)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000765"(regulation of cytoplasmic translation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR044445|interpro:IPR044446|interpro:IPR044447|mint:Q08211|rcsb pdb:3LLM|rcsb pdb:3VYX|rcsb pdb:3VYY|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-72163|go:"GO:1904973"(positive regulation of viral translation)|ensembl:ENSG00000135829(gene)|ensembl:ENST00000367549(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006260"(DNA replication)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0016604"(nuclear body) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2018/04/06 rogid:A0wZuIW8uezDFqFkBcQ7yDrVj6Q88776 rogid:b0VP2Frtvwa9WbYVMwB6TbV2uGU9606 intact-crc:3B5318C2D520ED0F false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99AU3 uniprotkb:O14654 intact:EBI-6150155 intact:EBI-356594|ensembl:ENSP00000505547 psi-mi:ns1_i18a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:88776(i18a0)|taxid:88776("Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157083|imex:IM-17331-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61813N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2N74|rcsb pdb:5UL6|rcsb pdb:6ATV|rcsb pdb:6DGK|rcsb pdb:6NU0|rcsb pdb:6OX7|rcsb pdb:6U28 ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2018/04/06 rogid:A0wZuIW8uezDFqFkBcQ7yDrVj6Q88776 rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606 intact-crc:3B5318C2D520ED0F false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99AU3 uniprotkb:Q99729 intact:EBI-6150155 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 psi-mi:ns1_i18a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:88776(i18a0)|taxid:88776("Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157083|imex:IM-17331-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61813N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2N74|rcsb pdb:5UL6|rcsb pdb:6ATV|rcsb pdb:6DGK|rcsb pdb:6NU0|rcsb pdb:6OX7|rcsb pdb:6U28 refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2018/04/06 rogid:A0wZuIW8uezDFqFkBcQ7yDrVj6Q88776 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 intact-crc:3B5318C2D520ED0F false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99AU3 uniprotkb:P61978 intact:EBI-6150155 intact:EBI-304185|intact:EBI-28971491|ensembl:ENSP00000317788|ensembl:ENSP00000353552|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q59F98|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62|uniprotkb:Q5T6W4|intact:EBI-3440248|uniprotkb:Q6IBN1 psi-mi:ns1_i18a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpk_human(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:88776(i18a0)|taxid:88776("Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157083|imex:IM-17331-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61813N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2N74|rcsb pdb:5UL6|rcsb pdb:6ATV|rcsb pdb:6DGK|rcsb pdb:6NU0|rcsb pdb:6OX7|rcsb pdb:6U28 ensembl:ENSG00000165119(gene)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000351839(transcript)|ensembl:ENST00000360384(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0002102"(podosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61978|rcsb pdb:1J5K|rcsb pdb:1KHM|rcsb pdb:1ZZI|rcsb pdb:1ZZJ|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9610379|rcsb pdb:1ZZK|refseq:NP_002131.2|refseq:NP_112552.1|refseq:NP_112553.1|ensembl:ENSP00000317788|ensembl:ENSP00000353552|ensembl:ENST00000376263|ensembl:ENSP00000365439|ensembl:ENST00000376281|ensembl:ENSP00000365458|refseq:NP_001305115.1|refseq:NP_001305116.1|refseq:NP_001305117.1|refseq:XP_016870157.1|refseq:XP_005252017.1|refseq:XP_005252020.1|refseq:XP_005252022.1|dip:DIP-31805N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2018/04/06 rogid:A0wZuIW8uezDFqFkBcQ7yDrVj6Q88776 rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606 intact-crc:3B5318C2D520ED0F false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99AU3 uniprotkb:Q96PV6 intact:EBI-6150155 intact:EBI-739546|intact:EBI-954056|uniprotkb:Q8NCX6|uniprotkb:Q8IZ27|uniprotkb:B0VJY9|intact:EBI-28984630|ensembl:ENSP00000318374|ensembl:ENSP00000478337|ensembl:ENSP00000478975|ensembl:ENSP00000480663|uniprotkb:A0A087WTE7 psi-mi:ns1_i18a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:leng8_human(display_long)|uniprotkb:LENG8(gene name)|psi-mi:LENG8(display_short)|uniprotkb:KIAA1932(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:88776(i18a0)|taxid:88776("Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157083|imex:IM-17331-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61813N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2N74|rcsb pdb:5UL6|rcsb pdb:6ATV|rcsb pdb:6DGK|rcsb pdb:6NU0|rcsb pdb:6OX7|rcsb pdb:6U28 refseq:NP_443157.1|ensembl:ENSG00000167615(gene)|ensembl:ENSG00000274305(gene)|ensembl:ENSG00000276458(gene)|ensembl:ENSG00000276681(gene)|ensembl:ENST00000326764(transcript)|ensembl:ENST00000617180(transcript)|ensembl:ENST00000621306(transcript)|ensembl:ENST00000622672(transcript)|go:"GO:0005634"(nucleus)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR005062(SAC3/GANP/Nin1/mts3/eIF-3 p25)|mint:Q96PV6|ensembl:ENSP00000318374|ensembl:ENST00000610314|ensembl:ENSP00000484494|ensembl:ENST00000611866|ensembl:ENSP00000479293|ensembl:ENST00000616932|ensembl:ENSP00000477813|ensembl:ENSP00000480663|ensembl:ENST00000617420|ensembl:ENSP00000481040|ensembl:ENSP00000478337|ensembl:ENSP00000478975|refseq:XP_011524717.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2018/04/06 rogid:A0wZuIW8uezDFqFkBcQ7yDrVj6Q88776 rogid:kwgKuV5NW0hITukndsYeyQHTdd09606 intact-crc:3B5318C2D520ED0F false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99AU3 uniprotkb:P43243 intact:EBI-6150155 intact:EBI-352602|ensembl:ENSP00000378284|ensembl:ENSP00000482895|uniprotkb:Q9UHW0|uniprotkb:Q9UQ27|uniprotkb:D3DQC3|uniprotkb:B7ZAV5 psi-mi:ns1_i18a0(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:matr3_human(display_long)|uniprotkb:KIAA0723(gene name synonym)|uniprotkb:MATR3(gene name)|psi-mi:MATR3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:88776(i18a0)|taxid:88776("Influenza A virus (strain A/Brevig Mission/1/1918 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157083|imex:IM-17331-42 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-61813N|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2N74|rcsb pdb:5UL6|rcsb pdb:6ATV|rcsb pdb:6DGK|rcsb pdb:6NU0|rcsb pdb:6OX7|rcsb pdb:6U28 ensembl:ENSG00000015479(gene)|ensembl:ENST00000394805(transcript)|ensembl:ENST00000618441(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:P43243|refseq:NP_001181883.1|refseq:NP_001181884.1|refseq:NP_061322.2|refseq:NP_954659.1|refseq:NP_001181885.1|refseq:NP_001269207.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2018/04/06 rogid:A0wZuIW8uezDFqFkBcQ7yDrVj6Q88776 rogid:3UZlyCZHgdr1SBgUctv9Ev7XBSQ9606 intact-crc:3B5318C2D520ED0F false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:O00571 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q7L2E3 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-1211456|uniprotkb:O94965|uniprotkb:Q7Z753|uniprotkb:Q96CH4|uniprotkb:Q9NUQ0|uniprotkb:A8K5F1|ensembl:ENSP00000392601|ensembl:ENSP00000405620|intact:EBI-21350949 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:dhx30_human(display_long)|uniprotkb:DHX30(gene name)|psi-mi:DHX30(display_short)|uniprotkb:KIAA0890(gene name synonym)|uniprotkb:DDX30(gene name synonym)|uniprotkb:DEAH box protein 30(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_055781.2|refseq:NP_619520.1|refseq:XP_011531796.1|refseq:XP_011531797.1|refseq:XP_016861406.1|ensembl:ENSG00000132153(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007417"(central nervous system development)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902775"(mitochondrial large ribosomal subunit assembly)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|mint:Q7L2E3|rcsb pdb:2DB2|ensembl:ENST00000445061(transcript)|ensembl:ENST00000446256(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:tb4GzZKLycraXS0NlVqj8reV3IQ9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q9UKM9 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-714796|uniprotkb:Q14621|uniprotkb:Q2M365|uniprotkb:Q5QPL8|uniprotkb:Q9BQX6|uniprotkb:Q9UJE3|ensembl:ENSP00000246194 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:raly_human(display_long)|uniprotkb:hnRNP associated with lethal yellow protein homolog(gene name synonym)|uniprotkb:Autoantigen p542(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein C-like 2(gene name synonym)|uniprotkb:RALY(gene name)|psi-mi:RALY(display_short)|uniprotkb:P542(gene name synonym)|uniprotkb:HNRPCL2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:XP_011526996.1|refseq:XP_011526997.1|ensembl:ENSG00000125970(gene)|ensembl:ENST00000246194(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903506"(regulation of nucleic acid-templated transcription)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR034502|interpro:IPR035979|mint:Q9UKM9|rcsb pdb:1WF1|refseq:NP_031393.2|refseq:NP_057951.1|refseq:XP_005260391.1|refseq:XP_005260393.1|refseq:XP_016883220.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:3hd0n2UW0FSRNvSJa2mqflVeorc9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q9NZI8 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-1053892|uniprotkb:C9JT33|ensembl:ENSP00000290341 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:if2b1_human(display_long)|uniprotkb:ZBP1(gene name synonym)|uniprotkb:IGF-II mRNA-binding protein 1(gene name synonym)|uniprotkb:Coding region determinant-binding protein(gene name synonym)|uniprotkb:VICKZ family member 1(gene name synonym)|uniprotkb:IGF2BP1(gene name)|psi-mi:IGF2BP1(display_short)|uniprotkb:Zipcode-binding protein 1(gene name synonym)|uniprotkb:CRDBP(gene name synonym)|uniprotkb:VICKZ1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_006537.3|refseq:NP_001153895.1|ensembl:ENSG00000159217(gene)|ensembl:ENST00000290341(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007399"(nervous system development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010610"(regulation of mRNA stability involved in response to stress)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022013"(pallium cell proliferation in forebrain)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0140059"(dendrite arborization)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034837|interpro:IPR034842|interpro:IPR035979|interpro:IPR036612|mint:Q9NZI8|rcsb pdb:3KRM|rcsb pdb:6QEY|reactome:R-HSA-428359|reactome:R-HSA-5687128|dip:DIP-38139N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:3Ps/PWWYr0WpYcx3G/AOiQEj+vc9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P61978 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-304185|intact:EBI-28971491|ensembl:ENSP00000317788|ensembl:ENSP00000353552|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q59F98|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62|uniprotkb:Q5T6W4|intact:EBI-3440248|uniprotkb:Q6IBN1 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpk_human(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000165119(gene)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000351839(transcript)|ensembl:ENST00000360384(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0002102"(podosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61978|rcsb pdb:1J5K|rcsb pdb:1KHM|rcsb pdb:1ZZI|rcsb pdb:1ZZJ|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9610379|rcsb pdb:1ZZK|refseq:NP_002131.2|refseq:NP_112552.1|refseq:NP_112553.1|ensembl:ENSP00000317788|ensembl:ENSP00000353552|ensembl:ENST00000376263|ensembl:ENSP00000365439|ensembl:ENST00000376281|ensembl:ENSP00000365458|refseq:NP_001305115.1|refseq:NP_001305116.1|refseq:NP_001305117.1|refseq:XP_016870157.1|refseq:XP_005252017.1|refseq:XP_005252020.1|refseq:XP_005252022.1|dip:DIP-31805N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q8N257 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-6150245|uniprotkb:Q5TA30|uniprotkb:Q3ZCP6|uniprotkb:A4FU05|ensembl:ENSP00000479284|ensembl:ENSP00000496342 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2b3b_human(display_long)|uniprotkb:H2BU1(gene name)|psi-mi:H2BU1(display_short)|uniprotkb:H2B type 12(gene name synonym)|uniprotkb:H2B.U histone 1(gene name synonym)|uniprotkb:HIST3H2BB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_778225.1|ensembl:ENSG00000196890(gene)|ensembl:ENSG00000285449(gene)|ensembl:ENST00000620438(transcript)|ensembl:ENST00000647549(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q8N257|rcsb pdb:6BIZ|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:MnRK2NXd2p3rWO8GPfErAa273eY9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P31943 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168|ensembl:ENSP00000377082|ensembl:ENSP00000397797|ensembl:ENSP00000492076|ensembl:ENSP00000495786 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_005511.1|refseq:NP_001244222.1|ensembl:ENSG00000169045(gene)|ensembl:ENSG00000284254(gene)|ensembl:ENST00000356731(transcript)|ensembl:ENST00000393432(transcript)|ensembl:ENST00000442819(transcript)|ensembl:ENST00000638505(transcript)|ensembl:ENST00000643310(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P62805 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q93079 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-352469|uniprotkb:Q4VB74|uniprotkb:B2R541|ensembl:ENSP00000479169 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2b1h_human(display_long)|uniprotkb:H2BC9(gene name)|psi-mi:H2BC9(display_short)|uniprotkb:H2B-clustered histone 9(gene name synonym)|uniprotkb:H2BFJ(gene name synonym)|uniprotkb:HIST1H2BH(gene name synonym)|uniprotkb:Histone H2B.j(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_003515.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|ensembl:ENSG00000275713(gene)|ensembl:ENST00000619466(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0097677"(STAT family protein binding)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:W+7KkrtV9xv7ELLxmJFnI4LQoME9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P07910 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-357966|uniprotkb:P22628|uniprotkb:Q53EX2|uniprotkb:Q59FD3|uniprotkb:Q5FWE8|uniprotkb:Q86SF8|uniprotkb:Q86U45|uniprotkb:Q96HK7|uniprotkb:Q96HM4|uniprotkb:Q96IY5|uniprotkb:Q9BTS3|uniprotkb:D3DS19|uniprotkb:D3DS22|intact:EBI-28976506|ensembl:ENSP00000404848|ensembl:ENSP00000451291|ensembl:ENSP00000452276 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpc_human(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001070910.1|refseq:NP_001070911.1|refseq:NP_004491.2|refseq:NP_112604.2|ensembl:ENSP00000404848|ensembl:ENST00000430246|ensembl:ENSP00000442816|ensembl:ENST00000553300|ensembl:ENSP00000450544|ensembl:ENSP00000451291|ensembl:ENST00000554969|ensembl:ENSP00000452276|ensembl:ENSP00000450725|ensembl:ENST00000555883|ensembl:ENSP00000450629|ensembl:ENST00000556628|ensembl:ENSP00000451652|ensembl:ENST00000556897|ensembl:ENSP00000451176|refseq:XP_011535010.1|refseq:XP_011535011.1|refseq:XP_011535012.1|refseq:XP_011535013.1|refseq:XP_011535014.1|refseq:XP_016876741.1|refseq:XP_016876742.1|dip:DIP-29854N|refseq:XP_006720188.1|ensembl:ENSG00000092199(gene)|ensembl:ENST00000420743(transcript)|ensembl:ENST00000554455(transcript)|ensembl:ENST00000557201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979|mint:P07910|rcsb pdb:1TXP|rcsb pdb:1WF2|rcsb pdb:2MXY|rcsb pdb:2MZ1|rcsb pdb:3LN4|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:Fj5tiH0wrNUjTnsURIg8dB8laMg9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P62807 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-354552|uniprotkb:Q4VB69|uniprotkb:P02278|uniprotkb:Q3B872|uniprotkb:Q93078|uniprotkb:Q93080|ensembl:ENSP00000321744|ensembl:ENSP00000348924|ensembl:ENSP00000366962|ensembl:ENSP00000380180|ensembl:ENSP00000445633|ensembl:ENSP00000483237|ensembl:ENSP00000489317 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2b1c_human(display_long)|uniprotkb:HIST1H2BG(gene name synonym)|uniprotkb:HIST1H2BI(gene name synonym)|uniprotkb:Histone H2B.1 A(gene name synonym)|uniprotkb:Histone H2B.a(gene name synonym)|uniprotkb:Histone H2B.g(gene name synonym)|uniprotkb:Histone H2B.h(gene name synonym)|uniprotkb:Histone H2B.k(gene name synonym)|uniprotkb:Histone H2B.l(gene name synonym)|uniprotkb:H2BC10(gene name)|psi-mi:H2BC10(display_short)|uniprotkb:H2BC4(gene name)|psi-mi:H2BC4(display_short)|uniprotkb:H2BC6(gene name)|psi-mi:H2BC6(display_short)|uniprotkb:H2BC7(gene name)|psi-mi:H2BC7(display_short)|uniprotkb:H2BC8(gene name)|psi-mi:H2BC8(display_short)|uniprotkb:H2BFA(gene name synonym)|uniprotkb:H2BFG(gene name synonym)|uniprotkb:H2BFH(gene name synonym)|uniprotkb:H2BFK(gene name synonym)|uniprotkb:H2BFL(gene name synonym)|uniprotkb:HIST1H2BC(gene name synonym)|uniprotkb:HIST1H2BE(gene name synonym)|uniprotkb:HIST1H2BF(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_003509.1|refseq:NP_003513.1|refseq:NP_003514.2|refseq:NP_003516.1|refseq:NP_003517.2|refseq:NP_066407.1|rcsb pdb:7A08|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|rcsb pdb:6XJD|ensembl:ENSG00000180596(gene)|ensembl:ENSG00000273802(gene)|ensembl:ENSG00000274290(gene)|ensembl:ENSG00000277224(gene)|ensembl:ENSG00000278588(gene)|ensembl:ENST00000314332(transcript)|ensembl:ENST00000356530(transcript)|ensembl:ENST00000377733(transcript)|ensembl:ENST00000396984(transcript)|ensembl:ENST00000541790(transcript)|ensembl:ENST00000614097(transcript)|ensembl:ENST00000634910(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0042802"(identical protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P62807|rcsb pdb:5GT0|rcsb pdb:5KGF|rcsb pdb:6ACO|rcsb pdb:6C0W|rcsb pdb:6FML|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6X59|rcsb pdb:6X5A|dip:DIP-32890N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:00sapwbWn8dtUr7qoPsRPUlL35A9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q92900 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-373471|uniprotkb:O00239|uniprotkb:O43343|uniprotkb:Q86Z25|uniprotkb:Q92842|ensembl:ENSP00000470142 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rent1_human(display_long)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:RENT1(gene name synonym)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_002902.2|refseq:NP_001284478.1|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR018999|interpro:IPR027417|interpro:IPR040812|interpro:IPR041677|interpro:IPR041679|mint:Q92900|rcsb pdb:2GJK|rcsb pdb:2GK6|rcsb pdb:2GK7|rcsb pdb:2IYK|rcsb pdb:2WJV|rcsb pdb:2WJY|rcsb pdb:2XZO|rcsb pdb:2XZP|rcsb pdb:6EJ5|rcsb pdb:6Z3R|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0006406"(mRNA export from nucleus)|dip:DIP-29875N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q5VTE0 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-877809 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ef1a3_human(display_long)|uniprotkb:EEF1A1P5(gene name)|psi-mi:EEF1A1P5(display_short)|uniprotkb:Eukaryotic elongation factor 1 A-like 3(gene name synonym)|uniprotkb:EEF1AL3(gene name synonym)|uniprotkb:Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR031157|reactome:R-HSA-156842|interpro:IPR027417 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:3t6tj3i+3CKTC1NsrHyBkeoRK789606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q99879 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-3893474|uniprotkb:Q6NWQ3|ensembl:ENSP00000477907 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2b1m_human(display_long)|uniprotkb:H2BC14(gene name)|psi-mi:H2BC14(display_short)|uniprotkb:H2BFE(gene name synonym)|uniprotkb:HIST1H2BM(gene name synonym)|uniprotkb:Histone H2B.e(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_003512.1|ensembl:ENSG00000273703(gene)|ensembl:ENST00000621112(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-912446|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:ETy0Ge+X/+GWAlBGq+YpQLc+DoE9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P52597 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-352986|ensembl:ENSP00000338477|ensembl:ENSP00000349573|ensembl:ENSP00000400433|ensembl:ENSP00000438061|ensembl:ENSP00000507787|ensembl:ENSP00000348345|uniprotkb:Q5T0N2|uniprotkb:Q96AU2|uniprotkb:B3KM84 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpf_human(display_long)|uniprotkb:HNRNPF(gene name)|psi-mi:HNRNPF(display_short)|uniprotkb:HNRPF(gene name synonym)|uniprotkb:Nucleolin-like protein mcs94-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P52597|rcsb pdb:2HGL|rcsb pdb:2HGM|rcsb pdb:2HGN|rcsb pdb:2KFY|rcsb pdb:2KG0|rcsb pdb:2KG1|rcsb pdb:3TFY|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensembl:ENSG00000169813(gene)|ensembl:ENST00000337970(transcript)|ensembl:ENST00000356053(transcript)|ensembl:ENST00000357065(transcript)|ensembl:ENST00000443950(transcript)|ensembl:ENST00000544000(transcript)|ensembl:ENST00000682386(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001091674.1|refseq:NP_001091675.1|refseq:NP_001091676.1|refseq:NP_001091677.1|refseq:NP_001091678.1|refseq:NP_004957.1|dip:DIP-33145N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:pblzpldZOa5vlZ+zGQY9qyWCxaw9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P62847 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-354515|uniprotkb:P16632|uniprotkb:Q7Z3D1|uniprotkb:Q5T0P7|uniprotkb:Q5T0P8|uniprotkb:E7EPK6|ensembl:ENSP00000478869 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs24_human(display_long)|uniprotkb:RPS24(gene name)|psi-mi:RPS24(display_short)|uniprotkb:Small ribosomal subunit protein eS24(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001135757.1|refseq:NP_001017.1|refseq:NP_001135755.1|refseq:NP_148982.1|ensembl:ENSG00000138326(gene)|ensembl:ENST00000613865(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR001976(Ribosomal protein S24e)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR018098|mint:P62847|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6XA1|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:M/qkRxabHx9PFaOM7EwKDOOwu7Q9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P14866 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-719024|uniprotkb:Q9H3P3|uniprotkb:A6ND69|uniprotkb:A6NIT8|ensembl:ENSP00000221419|ensembl:ENSP00000489021 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpl_human(display_long)|uniprotkb:HNRPL(gene name synonym)|uniprotkb:HNRNPL(gene name)|psi-mi:HNRNPL(display_short)|uniprotkb:P/OKcl.14(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001005335.1|refseq:NP_001524.2|refseq:XP_011525191.1|ensembl:ENSG00000282947(gene)|ensembl:ENST00000221419(transcript)|ensembl:ENST00000634753(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097157"(pre-mRNA intronic binding)|ensembl:ENSG00000104824(gene)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034816|interpro:IPR034817|interpro:IPR035005|interpro:IPR035008|interpro:IPR035979|mint:P14866|rcsb pdb:3R27|rcsb pdb:3TO8|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:1990904"(ribonucleoprotein complex)|dip:DIP-36355N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:vOfznm03e6Ottg6BptYHmR9qJEc9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P62280 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-1047710|uniprotkb:B2R4F5|uniprotkb:P04643|uniprotkb:Q498Y6|uniprotkb:Q6IRY0|ensembl:ENSP00000270625 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs11_human(display_long)|uniprotkb:RPS11(gene name)|psi-mi:RPS11(display_short)|uniprotkb:Small ribosomal subunit protein uS17(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001006.1|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000266(Ribosomal protein S17)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019979|interpro:IPR028333|interpro:IPR032440|mint:P62280|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|go:"GO:0005840"(ribosome)|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|ensembl:ENSG00000142534(gene)|ensembl:ENST00000270625(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6OM0|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:0fqJjtWAuz31VTKt2mbteRoi8vA9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P57053 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-2880265|ensembl:ENSP00000481622|uniprotkb:A0AVF9|uniprotkb:Q5R2W0 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2bfs_human(display_long)|uniprotkb:H2BS1(gene name)|psi-mi:H2BS1(display_short)|uniprotkb:H2B.S histone 1(gene name synonym)|uniprotkb:H2BFS(gene name synonym)|uniprotkb:Histone H2B.s(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000234289(gene)|ensembl:ENST00000599962(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0021762"(substantia nigra development)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-427359|refseq:XP_006723981.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:x8Ryb6Tm0nfhcmsoTX5h5ZRsN7g9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q12906 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-78756|uniprotkb:A8K6F2|uniprotkb:O43409|uniprotkb:Q6P1X1|uniprotkb:Q86XY7|uniprotkb:Q99544|uniprotkb:Q99545|uniprotkb:Q9BZH4|uniprotkb:Q9BZH5|uniprotkb:Q9NQ95|uniprotkb:Q9NQ96|uniprotkb:Q9NQ97|uniprotkb:Q9NQ98|uniprotkb:Q9NQ99|uniprotkb:Q9NQA0|uniprotkb:Q9NQA1|uniprotkb:Q9NQA2|uniprotkb:Q9NRN2|uniprotkb:Q9NRN3|uniprotkb:Q9NRN4|uniprotkb:Q9UMZ9|uniprotkb:Q9UN00|uniprotkb:Q9UN84|uniprotkb:Q9UNA2|ensembl:ENSP00000468156|intact:EBI-10970055|uniprotkb:G5E9M5 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ilf3_human(display_long)|uniprotkb:ILF3(gene name)|psi-mi:ILF3(display_short)|uniprotkb:MPHOSPH4(gene name synonym)|uniprotkb:NF90(gene name synonym)|uniprotkb:Nuclear factor of activated T-cells 90 kDa(gene name synonym)|uniprotkb:Double-stranded RNA-binding protein 76(gene name synonym)|uniprotkb:Translational control protein 80(gene name synonym)|uniprotkb:Nuclear factor associated with dsRNA(gene name synonym)|uniprotkb:M-phase phosphoprotein 4(gene name synonym)|uniprotkb:DRBF(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000129351(gene)|ensembl:ENST00000590261(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051607"(defense response to virus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR033099|interpro:IPR043519|mint:Q12906|rcsb pdb:2L33|rcsb pdb:3P1X|refseq:NP_001131145.1|refseq:NP_004507.2|refseq:NP_036350.2|refseq:NP_060090.2|refseq:NP_703194.1|refseq:XP_016882252.1|refseq:XP_011526286.2|dip:DIP-29853N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:iri+WBUtektANRSCpBO1XBCd9Wk9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P35268 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-354533|intact:EBI-1055963|uniprotkb:Q6IBD1|uniprotkb:B2R495|ensembl:ENSP00000346088 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl22_human(display_long)|uniprotkb:RPL22(gene name)|psi-mi:RPL22(display_short)|uniprotkb:Heparin-binding protein HBp15(gene name synonym)|uniprotkb:Epstein-Barr virus small RNA-associated protein(gene name synonym)|uniprotkb:EBER-associated protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL22(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_000974.1|ensembl:ENSG00000116251(gene)|ensembl:ENST00000234875(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008201"(heparin binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0045182"(translation regulator activity)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099577"(regulation of translation at presynapse, modulating synaptic transmission)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002671(Ribosomal protein L22e)|interpro:IPR038526|mint:P35268|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|reactome:R-HSA-72706|rcsb pdb:6Z6L|rcsb pdb:6Z6M|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:0TVillnqDkHmdTwxIedAJCVAdzY9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P52815 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-358272|uniprotkb:Q969U0|uniprotkb:Q9HCA2|uniprotkb:Q9UQJ3|ensembl:ENSP00000333837 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rm12_human(display_long)|uniprotkb:MRPL12(gene name)|psi-mi:MRPL12(display_short)|uniprotkb:RPML12(gene name synonym)|uniprotkb:5c5-2(gene name synonym)|uniprotkb:MRPL7(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein bL12m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_002940.2|ensembl:ENSG00000262814(gene)|ensembl:ENST00000333676(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006412"(translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR000206(Ribosomal protein L7/L12)|interpro:IPR008932(Ribosomal protein L7/L12, oligomerisation)|interpro:IPR013823(Ribosomal protein L7/L12, C-terminal)|interpro:IPR014719(Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like)|interpro:IPR036235|mint:P52815|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|dip:DIP-50865N|rcsb pdb:6ZSG|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:rs6bdQ5j/8fLRbXZqqS6GgR7AzI9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P23396 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-351193|uniprotkb:Q498B5|uniprotkb:Q8NI95|uniprotkb:B2R7N5|ensembl:ENSP00000433821|ensembl:ENSP00000434643|ensembl:ENSP00000436971|uniprotkb:J3KN86 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs3_human(display_long)|uniprotkb:RPS3(gene name)|psi-mi:RPS3(display_short)|uniprotkb:Small ribosomal subunit protein uS3(gene name synonym)|uniprotkb:OK/SW-cl.26(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_000996.2|ensembl:ENSG00000149273(gene)|ensembl:ENST00000524851(transcript)|ensembl:ENST00000527446(transcript)|ensembl:ENST00000531188(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR004044(K Homology, type 2)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|go:"GO:0071159"(NF-kappaB complex)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR018280|interpro:IPR036419|mint:P23396|rcsb pdb:1WH9|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|rcsb pdb:6QZP|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|refseq:NP_001243731.1|refseq:NP_001247436.1|refseq:NP_001247435.1|dip:DIP-33177N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:fsDW18AMR3YyEEIhMVcngYRWkps9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P31946 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q93077 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-725259|uniprotkb:O00775|uniprotkb:O00776|uniprotkb:O00777|uniprotkb:O00778|uniprotkb:Q540R1|uniprotkb:B2R4F7|ensembl:ENSP00000321389|ensembl:ENSP00000367022|ensembl:ENSP00000473534 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a1c_human(display_long)|uniprotkb:H2AC6(gene name)|psi-mi:H2AC6(display_short)|uniprotkb:H2A-clustered histone 6(gene name synonym)|uniprotkb:H2AFL(gene name synonym)|uniprotkb:HIST1H2AC(gene name synonym)|uniprotkb:Histone H2A/l(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_003503.1|ensembl:ENSG00000180573(gene)|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENST00000314088(transcript)|ensembl:ENST00000377791(transcript)|ensembl:ENST00000602637(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|rcsb pdb:6C0W|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:7A08|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|interpro:IPR032458 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:m00IdooZksbNGKHSsaVvGFVpcko9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q12905 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-357925|uniprotkb:A6NDB0|uniprotkb:Q5SR10|uniprotkb:Q5SR11|uniprotkb:Q7L7R3|uniprotkb:Q9BWD4|uniprotkb:Q9P1N0|uniprotkb:B2R8G7|ensembl:ENSP00000355011 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ilf2_human(display_long)|uniprotkb:PRO3063(orf name)|uniprotkb:NF45(gene name synonym)|uniprotkb:ILF2(gene name)|psi-mi:ILF2(display_short)|uniprotkb:Nuclear factor of activated T-cells 45 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_004506.2|refseq:NP_001254738.1|ensembl:ENSG00000143621(gene)|ensembl:ENST00000361891(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR043519|mint:Q12905|reactome:R-HSA-6798695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:HwUDuY6Ev7csoTThxZCW8nJT88o9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P33778 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-357986|uniprotkb:Q4KN36|ensembl:ENSP00000482674 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2b1b_human(display_long)|uniprotkb:H2BC3(gene name)|psi-mi:H2BC3(display_short)|uniprotkb:H2B-clustered histone 3(gene name synonym)|uniprotkb:H2BFF(gene name synonym)|uniprotkb:HIST1H2BB(gene name synonym)|uniprotkb:Histone H2B.1(gene name synonym)|uniprotkb:Histone H2B.f(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_066406.1|dip:DIP-47505N|ensembl:ENSG00000276410(gene)|ensembl:ENST00000615966(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P33778|rcsb pdb:3X1S|rcsb pdb:3X1U|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:l15lrchv4onuihbdZ+yWJQd35Ss9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P05141 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P0C0S8 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:O60506 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-1024357|uniprotkb:Q53H05|uniprotkb:Q5TCG2|uniprotkb:Q8IW78|uniprotkb:Q8N599|uniprotkb:Q96LC1|uniprotkb:Q96LC2|uniprotkb:Q9Y583|uniprotkb:Q5TCG3|uniprotkb:E1P501|uniprotkb:E1P502|ensembl:ENSP00000358635|ensembl:ENSP00000503783|ensembl:ENSP00000504706 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpq_human(display_long)|uniprotkb:Synaptotagmin-binding, cytoplasmic RNA-interacting protein(gene name synonym)|uniprotkb:Glycine- and tyrosine-rich RNA-binding protein(gene name synonym)|uniprotkb:NS1-associated protein 1(gene name synonym)|uniprotkb:SYNCRIP(gene name)|psi-mi:SYNCRIP(display_short)|uniprotkb:HNRPQ(gene name synonym)|uniprotkb:NSAP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001153145.1|refseq:NP_001153146.1|refseq:NP_001153147.1|refseq:NP_001240700.1|refseq:NP_001153148.1|refseq:NP_001153149.1|refseq:NP_006363.4|ensembl:ENSG00000135316(gene)|ensembl:ENST00000369622(transcript)|ensembl:ENST00000676688(transcript)|ensembl:ENST00000678355(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034544|interpro:IPR034548|interpro:IPR035979|interpro:IPR041337|mint:O60506|rcsb pdb:2DGU|rcsb pdb:2MXT|rcsb pdb:2NBB|rcsb pdb:6KOR|refseq:XP_016865667.1|refseq:XP_005248694.1|dip:DIP-35540N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:2rDkXIp/wWzTOoVtN7Bd3uqZo689606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q08380 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-354956|ensembl:ENSP00000262776|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000108679(gene)|ensembl:ENST00000262776(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017448(Speract/scavenger receptor related)|go:"GO:0007155"(cell adhesion)|interpro:IPR036772|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|refseq:NP_005558.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P62269 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-352451|ensembl:ENSP00000211372|ensembl:ENSP00000393241|ensembl:ENSP00000403175|ensembl:ENSP00000412583|ensembl:ENSP00000416110|uniprotkb:P25232|uniprotkb:Q6IPF8|uniprotkb:Q5SUJ3 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs18_human(display_long)|uniprotkb:RPS18(gene name)|psi-mi:RPS18(display_short)|uniprotkb:D6S218E(gene name synonym)|uniprotkb:Ke-3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS13(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_072045.1|ensembl:ENSG00000096150(gene)|ensembl:ENSG00000223367(gene)|ensembl:ENSG00000226225(gene)|ensembl:ENSG00000231500(gene)|ensembl:ENSG00000235650(gene)|ensembl:ENST00000211372(transcript)|ensembl:ENST00000434122(transcript)|ensembl:ENST00000439602(transcript)|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENST00000454021(transcript)|ensembl:ENST00000457341(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001892(Ribosomal protein S13)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR018269|interpro:IPR027437|mint:P62269|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|dip:DIP-32892N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:yOHgKM/BuvgGdqp1OEVPeuiABg89606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P26599 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-350540|ensembl:ENSP00000014112|intact:EBI-744534|uniprotkb:Q9BUQ0 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ptbp1_human(display_long)|uniprotkb:PTBP1(gene name)|psi-mi:PTBP1(display_short)|uniprotkb:PTB(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein I(gene name synonym)|uniprotkb:57 kDa RNA-binding protein PPTB-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_002810.1|refseq:NP_114367.1|refseq:NP_114368.1|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0016020"(membrane)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0051148"(negative regulation of muscle cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034798|interpro:IPR035000|interpro:IPR035001|interpro:IPR035979|mint:P26599|rcsb pdb:1QM9|rcsb pdb:1SJQ|ensembl:ENSG00000011304(gene)|ensembl:ENST00000349038(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0008380"(RNA splicing)|rcsb pdb:2AD9|rcsb pdb:2ADB|rcsb pdb:2ADC|rcsb pdb:2EVZ|rcsb pdb:2N3O|rcsb pdb:3ZZY|rcsb pdb:3ZZZ|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|rcsb pdb:1SJR - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:fkSnYJELgHxDP0oAQEjBmSX0HIs9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P55265 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-2462104|uniprotkb:B1AQR0|uniprotkb:O15223|uniprotkb:O43859|uniprotkb:O43860|uniprotkb:Q9BYM3|uniprotkb:Q9BYM4|uniprotkb:B1AQQ9|uniprotkb:D3DV76|ensembl:ENSP00000357459 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:dsrad_human(display_long)|uniprotkb:ADAR(gene name)|psi-mi:ADAR(display_short)|uniprotkb:ADAR1(gene name synonym)|uniprotkb:DSRAD(gene name synonym)|uniprotkb:G1P1(gene name synonym)|uniprotkb:IFI4(gene name synonym)|uniprotkb:136 kDa double-stranded RNA-binding protein(gene name synonym)|uniprotkb:K88DSRBP(gene name synonym)|uniprotkb:Interferon-inducible protein 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001020278.1|refseq:NP_001102.2|refseq:NP_001180424.1|refseq:NP_056655.2|refseq:NP_056656.2|refseq:XP_006711174.1|refseq:XP_006711175.1|refseq:XP_006711176.1|dip:DIP-29310N|ensembl:ENSG00000160710(gene)|ensembl:ENST00000368474(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002566"(somatic diversification of immune receptors via somatic mutation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0008251"(tRNA-specific adenosine deaminase activity)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016553"(base conversion or substitution editing)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900369"(negative regulation of RNA interference)|interpro:IPR002466(Adenosine deaminase/editase)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371|interpro:IPR044456|interpro:IPR044457|mint:P55265|rcsb pdb:1QBJ|rcsb pdb:1QGP|rcsb pdb:1XMK|rcsb pdb:2ACJ|rcsb pdb:2GXB|rcsb pdb:2L54|rcsb pdb:2MDR|rcsb pdb:3F21|rcsb pdb:3F22|rcsb pdb:3F23|rcsb pdb:3IRQ|rcsb pdb:3IRR|rcsb pdb:5ZU1|rcsb pdb:5ZUO|rcsb pdb:5ZUP|rcsb pdb:7C0I|reactome:R-HSA-75102|reactome:R-HSA-77042|reactome:R-HSA-909733|go:"GO:0051607"(defense response to virus) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:rP/Yr/h8WLSFNdIuqWnYtZjZ9qI9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P58876 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-4409942|ensembl:ENSP00000289316|ensembl:ENSP00000367008 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2b1d_human(display_long)|uniprotkb:Histone H2B.b(gene name synonym)|uniprotkb:H2BC5(gene name)|psi-mi:H2BC5(display_short)|uniprotkb:H2B-clustered histone 5(gene name synonym)|uniprotkb:H2BFB(gene name synonym)|uniprotkb:HIRA-interacting protein 2(gene name synonym)|uniprotkb:HIRIP2(gene name synonym)|uniprotkb:HIST1H2BD(gene name synonym)|uniprotkb:Histone H2B.1 B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_066407.1|refseq:NP_619790.1|ensembl:ENSG00000158373(gene)|ensembl:ENST00000289316(transcript)|ensembl:ENST00000377777(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P58876|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005634"(nucleus) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:07VBw5MCphdkMydMOPSjVqpGriI9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q9NNW5 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-1568315|uniprotkb:B4DHK2|uniprotkb:Q3MIT1|uniprotkb:Q9UF63|ensembl:ENSP00000477389 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:wdr6_human(display_long)|uniprotkb:WDR6(gene name)|psi-mi:WDR6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_060501.3|refseq:NP_001307475.1|refseq:NP_001307476.1|ensembl:ENSG00000178252(gene)|ensembl:ENST00000608424(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0030488"(tRNA methylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR001680(WD40 repeat)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9NNW5|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:gYSDkyuDdKhj387/1P3bhpKJXy89606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P15880 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-443446|ensembl:ENSP00000341885|uniprotkb:Q3MIB1|uniprotkb:B2R5G0|uniprotkb:D3DU82 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs2_human(display_long)|uniprotkb:RPS2(gene name)|psi-mi:RPS2(display_short)|uniprotkb:RPS4(gene name synonym)|uniprotkb:40S ribosomal protein S4(gene name synonym)|uniprotkb:Protein LLRep3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|rcsb pdb:6OLG|rcsb pdb:6OLI|interpro:IPR018192|rcsb pdb:6OLZ|interpro:IPR020568|mint:P15880|rcsb pdb:4UG0|rcsb pdb:6OM0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6EK0|rcsb pdb:6G18|rcsb pdb:6XA1|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6G5H|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7JQB|rcsb pdb:7JQC|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-3214858|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8876725|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:7A09|ensembl:ENSG00000140988(gene)|ensembl:ENST00000343262(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045296"(cadherin binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR005711(Ribosomal protein S5, eukaryotic/archaeal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|refseq:NP_002943.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:JUr2Y3cGk00S8KaTVPymshfaHhc9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P22626 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q92841 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-746012|uniprotkb:Q69YT1|uniprotkb:Q6ICD6|uniprotkb:H3BLZ8|uniprotkb:B1AHM0|ensembl:ENSP00000385536 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ddx17_human(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:RNA-dependent helicase p72(gene name synonym)|uniprotkb:DEAD box protein p72(gene name synonym)|uniprotkb:DDX17(gene name)|psi-mi:DDX17(display_short)|uniprotkb:DEAD box protein p82(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_006377.2|ensembl:ENSG00000100201(gene)|ensembl:ENST00000403230(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q92841|rcsb pdb:6UV0|rcsb pdb:6UV1|rcsb pdb:6UV2|rcsb pdb:6UV3|rcsb pdb:6UV4|reactome:R-HSA-3899300|dip:DIP-29843N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:3UhUuhRSZg/zlM7UPDKYCqNmUho9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P62258 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P62701 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-354303|uniprotkb:P12631|uniprotkb:P12750|uniprotkb:P27576|uniprotkb:Q14727|uniprotkb:P55831|uniprotkb:Q6IPY4|ensembl:ENSP00000362744 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs4x_human(display_long)|uniprotkb:RPS4X(gene name)|psi-mi:RPS4X(display_short)|uniprotkb:CCG2(gene name synonym)|uniprotkb:RPS4(gene name synonym)|uniprotkb:SCAR(gene name synonym)|uniprotkb:Single copy abundant mRNA protein(gene name synonym)|uniprotkb:SCR10(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_000998.1|rcsb pdb:6OLI|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000198034(gene)|ensembl:ENST00000316084(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000876(Ribosomal protein S4e)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005824(KOW)|interpro:IPR013843(Ribosomal protein S4e, N-terminal)|interpro:IPR013845(Ribosomal protein S4e, central)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR018199|interpro:IPR032277|interpro:IPR036986|interpro:IPR038237|interpro:IPR041982|mint:P62701|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|go:"GO:0045727"(positive regulation of translation)|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:2ZuLXqBSDkK0CtN3mnIDoFAR8yI9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q9HCE1 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028|ensembl:ENSP00000358659|ensembl:ENSP00000399797 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|refseq:NP_001308253.1|ensembl:ENSG00000155363(gene)|ensembl:ENST00000357443(transcript)|ensembl:ENST00000369645(transcript)|ensembl:ENST00000413052(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043186"(P granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041679|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-8936459|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q16778 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-1056125|uniprotkb:A3KMC7|uniprotkb:Q4KMY1|uniprotkb:Q5QNX0|uniprotkb:Q9UE88|uniprotkb:A8K110|ensembl:ENSP00000358151 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2b2e_human(display_long)|uniprotkb:H2BC21(gene name)|psi-mi:H2BC21(display_short)|uniprotkb:H2B-clustered histone 21(gene name synonym)|uniprotkb:H2BFQ(gene name synonym)|uniprotkb:HIST2H2BE(gene name synonym)|uniprotkb:Histone H2B-GL105(gene name synonym)|uniprotkb:Histone H2B.q(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_003519.1|ensembl:ENSG00000184678(gene)|ensembl:ENST00000369155(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q16778|rcsb pdb:4NFT|rcsb pdb:6A7U|rcsb pdb:6KBB|rcsb pdb:6M4D|rcsb pdb:6M4G|rcsb pdb:6M4H|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|rcsb pdb:7BXT|dip:DIP-39324N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:jh5U2ATjpAVt5DYOgr9YbcVdEzw9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q9Y2I1 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-2688731|uniprotkb:Q6PIB4|uniprotkb:Q9UEU4|uniprotkb:Q7L8M3|uniprotkb:Q6PGP3|uniprotkb:Q9UFW3|uniprotkb:Q7Z2X6|uniprotkb:Q9UES6|uniprotkb:C9J245|ensembl:ENSP00000339958|ensembl:ENSP00000418232 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:nisch_human(display_long)|uniprotkb:IRAS(gene name synonym)|uniprotkb:KIAA0975(gene name synonym)|uniprotkb:Imidazoline receptor 1(gene name synonym)|uniprotkb:Imidazoline receptor antisera-selected protein(gene name synonym)|uniprotkb:Imidazoline-1 receptor(gene name synonym)|uniprotkb:Imidazoline-1 receptor candidate protein(gene name synonym)|uniprotkb:NISCH(gene name)|psi-mi:NISCH(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_009115.2|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048243"(norepinephrine secretion)|go:"GO:0055037"(recycling endosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001683(Phox-like)|interpro:IPR032675|interpro:IPR036871|interpro:IPR037904|mint:Q9Y2I1|rcsb pdb:3P0C|reactome:R-HSA-9013149|reactome:R-HSA-9696264|reactome:R-HSA-9696270|ensembl:ENSG00000010322(gene)|ensembl:ENST00000345716(transcript)|ensembl:ENST00000479054(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032228"(regulation of synaptic transmission, GABAergic)|refseq:NP_001263222.1|refseq:NP_001263223.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:GuBgG6MUrD5p1hIhGGmrtCjT0jQ9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q96KK5 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-6147668|ensembl:ENSP00000366679 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a1h_human(display_long)|uniprotkb:H2AC12(gene name)|psi-mi:H2AC12(display_short)|uniprotkb:H2A-clustered histone 12(gene name synonym)|uniprotkb:HIST1H2AH(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:Histone H2A/s(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_542163.1|dip:DIP-61699N|ensembl:ENSG00000274997(gene)|ensembl:ENST00000377459(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:Oa322n+evy8Cu0E9cWTEdYwQPKM9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q6FI13 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-353620|uniprotkb:P20670|uniprotkb:B2R5F0|ensembl:ENSP00000358155|ensembl:ENSP00000475814 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a2a_human(display_long)|uniprotkb:H2AC18(gene name)|psi-mi:H2AC18(display_short)|uniprotkb:H2AC19(gene name)|psi-mi:H2AC19(display_short)|uniprotkb:H2A-clustered histone 18(gene name synonym)|uniprotkb:H2A-clustered histone 19(gene name synonym)|uniprotkb:H2AFO(gene name synonym)|uniprotkb:HIST2H2AA(gene name synonym)|uniprotkb:HIST2H2AA3(gene name synonym)|uniprotkb:HIST2H2AA4(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/o(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001035807.1|refseq:NP_003507.1|ensembl:ENSG00000203812(gene)|ensembl:ENSG00000272196(gene)|ensembl:ENST00000369159(transcript)|ensembl:ENST00000607355(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6Y5D|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|dip:DIP-33167N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:PMuIm2XMN5q4wk+wYJ94mmnCe4w9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q9Y224 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-1104547|ensembl:ENSP00000261700 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rtraf_human(display_long)|uniprotkb:RTRAF(gene name)|psi-mi:RTRAF(display_short)|uniprotkb:C14orf166(gene name synonym)|uniprotkb:CLE7 homolog(gene name synonym)|uniprotkb:CGI-99(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_057123.1|ensembl:ENSG00000087302(gene)|ensembl:ENST00000261700(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050658"(RNA transport)|go:"GO:0072669"(tRNA-splicing ligase complex)|go:"GO:0072686"(mitotic spindle)|interpro:IPR019265|mint:Q9Y224|reactome:R-HSA-6784531 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:KRP0BO8XmEAtBag6wdctMHgVaEI9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P63104 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q16777 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-5325566|ensembl:ENSP00000332194|uniprotkb:Q6DRA7|uniprotkb:Q8IUE5 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a2c_human(display_long)|uniprotkb:H2AC20(gene name)|psi-mi:H2AC20(display_short)|uniprotkb:H2A-clustered histone 20(gene name synonym)|uniprotkb:H2AFQ(gene name synonym)|uniprotkb:HIST2H2AC(gene name synonym)|uniprotkb:Histone H2A-GL101(gene name synonym)|uniprotkb:Histone H2A/q(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-5689603|ensembl:ENSG00000184260(gene)|ensembl:ENST00000331380(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q16777|rcsb pdb:6Y5E|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|refseq:NP_003508.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:Wejrpp9wK3GvA4ahJDVyEH+cwlQ9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q8WWM7 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-948363|ensembl:ENSP00000338718|uniprotkb:O95135|uniprotkb:Q6NVJ8|uniprotkb:Q6PJW6|uniprotkb:Q8IU61|uniprotkb:Q8IU95|uniprotkb:Q8WWM3|uniprotkb:Q8WWM4|uniprotkb:Q8WWM5|uniprotkb:Q8WWM6|uniprotkb:Q99703|uniprotkb:B9EGM2|uniprotkb:E9PAR9|uniprotkb:A8K1R6|uniprotkb:Q63ZY4 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:atx2l_human(display_long)|uniprotkb:Ataxin-2 domain protein(gene name synonym)|uniprotkb:Ataxin-2-related protein(gene name synonym)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short)|uniprotkb:A2D(gene name synonym)|uniprotkb:A2LG(gene name synonym)|uniprotkb:A2LP(gene name synonym)|uniprotkb:A2RP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000168488(gene)|ensembl:ENST00000336783(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045296"(cadherin binding)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR025852|mint:Q8WWM7|refseq:NP_009176.2|refseq:NP_663760.1|refseq:NP_680780.1|refseq:NP_680781.1|refseq:XP_005255123.1|refseq:NP_059867.3|refseq:NP_680782.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:t7lrS10IM/5pt+rrbqBRowZ6b+09606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P09651 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-352662|uniprotkb:Q3MIB7|uniprotkb:Q6PJZ7|ensembl:ENSP00000341826|ensembl:ENSP00000503610|uniprotkb:A8K4Z8|intact:EBI-2556572 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:roa1_human(display_long)|uniprotkb:HNRNPA1(gene name)|psi-mi:HNRNPA1(display_short)|uniprotkb:HNRPA1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:Single-strand RNA-binding protein(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_002127.1|refseq:NP_112420.1|ensembl:ENSG00000135486(gene)|ensembl:ENST00000340913(transcript)|ensembl:ENST00000677210(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|rcsb pdb:2LYV|rcsb pdb:2UP1|rcsb pdb:4YOE|rcsb pdb:5MPG|rcsb pdb:5MPL|rcsb pdb:5ZGD|rcsb pdb:5ZGL|rcsb pdb:6BXX|rcsb pdb:6DCL|rcsb pdb:6J60|rcsb pdb:7BX7|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035198"(miRNA binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051170"(import into nucleus)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR034845|interpro:IPR035979|mint:P09651|rcsb pdb:1HA1|rcsb pdb:1L3K|rcsb pdb:1PGZ|rcsb pdb:1PO6|rcsb pdb:1U1K|rcsb pdb:1U1L|rcsb pdb:1U1M|rcsb pdb:1U1N|rcsb pdb:1U1O|rcsb pdb:1U1P|rcsb pdb:1U1Q|rcsb pdb:1U1R|rcsb pdb:1UP1|rcsb pdb:2H4M|refseq:XP_005268883.1|dip:DIP-29338N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:ECXjsLRVtNc/aOw90tEFxowHc6c9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:O14979 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-299727|ensembl:ENSP00000295470|ensembl:ENSP00000422040|ensembl:ENSP00000483254|uniprotkb:Q6SPF2|uniprotkb:Q7KZ74|uniprotkb:Q7KZ75|uniprotkb:Q96IM0|uniprotkb:Q96S43 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrdl_human(display_long)|uniprotkb:HNRNPDL(gene name)|psi-mi:HNRNPDL(display_short)|uniprotkb:AU-rich element RNA-binding factor(gene name synonym)|uniprotkb:HNRPDL(gene name synonym)|uniprotkb:JKT41-binding protein(gene name synonym)|uniprotkb:JKTBP(gene name synonym)|uniprotkb:Protein laAUF1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000152795(gene)|ensembl:ENST00000295470(transcript)|ensembl:ENST00000502762(transcript)|ensembl:ENST00000621267(transcript)|go:"GO:0003677"(DNA binding)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034847|interpro:IPR035979|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|mint:O14979|go:"GO:0003723"(RNA binding)|reactome:R-HSA-8950505|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034046"("poly(G) binding")|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001193929.1|refseq:NP_112740.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:oOnEEar8AtKO5G6ldehucaRr4kM9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q8N163 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|ensembl:ENSP00000310670|ensembl:ENSP00000373930|uniprotkb:B2RB79|uniprotkb:D3DSR6 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_066997.3|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|interpro:IPR028811|mint:Q8N163|reactome:R-HSA-3371453|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|dip:DIP-38122N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q5QNW6 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-6147754|uniprotkb:B4DLA9|uniprotkb:A8K0U9|ensembl:ENSP00000358164 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2b2f_human(display_long)|uniprotkb:H2BC18(gene name)|psi-mi:H2BC18(display_short)|uniprotkb:H2B-clustered histone 18(gene name synonym)|uniprotkb:HIST2H2BF(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001019770.1|refseq:NP_001154806.1|ensembl:ENSG00000203814(gene)|ensembl:ENST00000369167(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q5QNW6|rcsb pdb:6MUO|rcsb pdb:6MUP|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-5689880|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:Pr400UVIaD7O446lc9vZeStUKn09606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q9BUJ2 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-1018153|uniprotkb:O76022|uniprotkb:Q6ZSZ0|uniprotkb:Q7L8P4|uniprotkb:Q8N6Z4|uniprotkb:Q96G37|uniprotkb:Q9HAL3|uniprotkb:Q9UG75|intact:EBI-3183399|intact:EBI-2339292|uniprotkb:B3KMW7|ensembl:ENSP00000375863|intact:EBI-2563529 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrl1_human(display_long)|uniprotkb:E1BAP5(gene name synonym)|uniprotkb:HNRNPUL1(gene name)|psi-mi:HNRNPUL1(display_short)|uniprotkb:HNRPUL1(gene name synonym)|uniprotkb:Adenovirus early region 1B-associated protein 5(gene name synonym)|uniprotkb:E1B-55 kDa-associated protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_008971.2|refseq:NP_653333.1|go:"GO:0009615"(response to virus)|go:"GO:0019899"(enzyme binding)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027025|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q9BUJ2|reactome:R-HSA-72163|ensembl:ENSG00000105323(gene)|ensembl:ENST00000392006(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|refseq:NP_001308140.1|refseq:NP_001308137.1|dip:DIP-39419N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:IahA7SVR1NmvldrWKQlAwApinQE9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q99880 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-1237119|uniprotkb:Q52LW9|uniprotkb:B2R5A3|ensembl:ENSP00000366618 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2b1l_human(display_long)|uniprotkb:H2BC13(gene name)|psi-mi:H2BC13(display_short)|uniprotkb:H2BFC(gene name synonym)|uniprotkb:HIST1H2BL(gene name synonym)|uniprotkb:Histone H2B.c(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_003510.1|dip:DIP-38154N|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|ensembl:ENSG00000185130(gene)|ensembl:ENST00000377401(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|interpro:IPR009072(Histone-fold)|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5250924|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:vVD3xoHavMKCopzEez7zarZBKFc9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:O15226 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-766011|uniprotkb:Q4VC41|uniprotkb:Q9UJ91|uniprotkb:G3V1N1|ensembl:ENSP00000304803 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:nkrf_human(display_long)|uniprotkb:Transcription factor NRF(gene name synonym)|uniprotkb:Protein ITBA4(gene name synonym)|uniprotkb:NKRF(gene name)|psi-mi:NKRF(display_short)|uniprotkb:ITBA4(gene name synonym)|uniprotkb:NRF(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001166958.1|refseq:NP_001166959.1|refseq:NP_060014.2|refseq:XP_011529667.1|dip:DIP-34570N|ensembl:ENSG00000186416(gene)|ensembl:ENST00000304449(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000467(D111/G-patch)|interpro:IPR001374(Single-stranded nucleic acid binding R3H)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036867|mint:O15226|rcsb pdb:6SH6|rcsb pdb:6SH7|interpro:IPR034071 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:jH7qlOvuAHKsjuOyzDpBonpgtF09606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P07437 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P51991 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-1050760|uniprotkb:Q53RW7|uniprotkb:Q6URK5|uniprotkb:D3DPF4|ensembl:ENSP00000376309|ensembl:ENSP00000416340|ensembl:ENSP00000503593|ensembl:ENSP00000504135|ensembl:ENSP00000504152 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:roa3_human(display_long)|uniprotkb:HNRPA3(gene name synonym)|uniprotkb:HNRNPA3(gene name)|psi-mi:HNRNPA3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_919223.1|refseq:NP_001317178.1|ensembl:ENSG00000170144(gene)|ensembl:ENST00000392524(transcript)|ensembl:ENST00000435711(transcript)|ensembl:ENST00000676629(transcript)|ensembl:ENST00000678111(transcript)|ensembl:ENST00000679159(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0051028"(mRNA transport)|go:"GO:0051033"(RNA transmembrane transporter activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034513|interpro:IPR034516|interpro:IPR035979|mint:P51991|reactome:R-HSA-72163|reactome:R-HSA-72203 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:bbg0nIdhEHomcwtgZhT2yHy7+nU9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P27986 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-79464|intact:EBI-28974553|ensembl:ENSP00000428056|ensembl:ENSP00000429277|uniprotkb:Q15747|uniprotkb:Q4VBZ7|uniprotkb:Q53EM6|uniprotkb:Q8IXA2|uniprotkb:Q8N1C5|uniprotkb:D3DWA0|uniprotkb:B3KT19|uniprotkb:E7EX19 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:p85a_human(display_long)|uniprotkb:PIK3R1(gene name)|psi-mi:PIK3R1(display_short)|uniprotkb:GRB1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001229395.1|refseq:NP_852556.2|refseq:NP_852664.1|refseq:NP_852665.1|ensembl:ENSG00000145675(gene)|ensembl:ENST00000521381(transcript)|ensembl:ENST00000521657(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|ensembl:ENST00000320694|ensembl:ENSP00000323512|ensembl:ENST00000336483|ensembl:ENSP00000338554|ensembl:ENSP00000428056|ensembl:ENSP00000429277|ensembl:ENST00000523872|ensembl:ENSP00000430098|rcsb pdb:5SXA|rcsb pdb:5SXB|rcsb pdb:5SXC|rcsb pdb:5SXD|rcsb pdb:5SXE|rcsb pdb:5SXF|rcsb pdb:5SXI|rcsb pdb:5SXJ|rcsb pdb:5SXK|rcsb pdb:5UBT|rcsb pdb:5UK8|rcsb pdb:5UKJ|rcsb pdb:5SX9|rcsb pdb:5UL1|rcsb pdb:5VLR|rcsb pdb:5XGH|rcsb pdb:5XGI|rcsb pdb:5XGJ|rcsb pdb:6NCT|rcsb pdb:6PYR|rcsb pdb:6PYU|reactome:R-HSA-1660499|rcsb pdb:7CIO|rcsb pdb:7LM2|reactome:R-HSA-180292|reactome:R-HSA-109704|reactome:R-HSA-1839117|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1236382|reactome:R-HSA-186763|reactome:R-HSA-1963642|reactome:R-HSA-1250342|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-198203|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-1433557|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-430116|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654689|reactome:R-HSA-5654695|reactome:R-HSA-5654710|reactome:R-HSA-5654720|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9603381|reactome:R-HSA-9607240|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9703465|reactome:R-HSA-9703648|reactome:R-HSA-983695|reactome:R-HSA-5655253|reactome:R-HSA-5655302|reactome:R-HSA-5673001|reactome:R-HSA-6785807|reactome:R-HSA-6811558|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-5655291|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9027276|reactome:R-HSA-9028335|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0043559"(insulin binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1990578"(perinuclear endoplasmic reticulum membrane)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035591|interpro:IPR036028|interpro:IPR036860|interpro:IPR044124|mint:P27986|rcsb pdb:1A0N|rcsb pdb:1AZG|rcsb pdb:1H9O|rcsb pdb:1PBW|rcsb pdb:1PHT|rcsb pdb:1PIC|rcsb pdb:1PKS|rcsb pdb:1PKT|rcsb pdb:2IUG|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|rcsb pdb:2IUH|rcsb pdb:2IUI|rcsb pdb:2RD0|rcsb pdb:3HHM|rcsb pdb:3HIZ|rcsb pdb:3I5R|rcsb pdb:3I5S|rcsb pdb:4A55|rcsb pdb:4JPS|rcsb pdb:4L1B|rcsb pdb:4L23|rcsb pdb:4L2Y|rcsb pdb:4OVU|rcsb pdb:4OVV|rcsb pdb:4WAF|rcsb pdb:4YKN|rcsb pdb:4ZOP|rcsb pdb:5AUL|rcsb pdb:5FI4|rcsb pdb:5GJI|rcsb pdb:5ITD|rcsb pdb:5M6U|rcsb pdb:5SW8|rcsb pdb:5SWG|rcsb pdb:5SWO|rcsb pdb:2V1Y|rcsb pdb:5SWP|rcsb pdb:5SWR|rcsb pdb:5SWT|rcsb pdb:5SX8|refseq:XP_016865074.1|refseq:XP_005248599.1|dip:DIP-119N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:pANLtVCSWVr64OXaS6bCjGBwfig9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q86U42 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-1226435|uniprotkb:O43484|uniprotkb:D3DS49|ensembl:ENSP00000216727 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pabp2_human(display_long)|uniprotkb:PABPN1(gene name)|psi-mi:PABPN1(display_short)|uniprotkb:PAB2(gene name synonym)|uniprotkb:PABP2(gene name synonym)|uniprotkb:"Poly(A)-binding protein II"(gene name synonym)|uniprotkb:Polyadenylate-binding nuclear protein 1(gene name synonym)|uniprotkb:"Nuclear poly(A)-binding protein 1"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_004634.1|dip:DIP-37968N|go:"GO:0000165"(MAPK cascade)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|ensembl:ENSG00000100836(gene)|ensembl:ENST00000216727(transcript)|go:"GO:0006936"(muscle contraction)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1904247"(positive regulation of polynucleotide adenylyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034911|interpro:IPR035979|mint:Q86U42|rcsb pdb:3B4D|rcsb pdb:3B4M|rcsb pdb:3UCG|reactome:R-HSA-168315|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0070063"(RNA polymerase binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:NxWuFTvVqshfu+ZIsZMIZEdSk2k9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:O00425 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-1058566|ensembl:ENSP00000258729|uniprotkb:Q63HM0|uniprotkb:A0A4Z5|uniprotkb:Q6MZZ2|uniprotkb:Q86VB1|intact:EBI-2560196 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:if2b3_human(display_long)|uniprotkb:IGF2BP3(gene name)|psi-mi:IGF2BP3(display_short)|uniprotkb:IMP3(gene name synonym)|uniprotkb:KOC1(gene name synonym)|uniprotkb:VICKZ3(gene name synonym)|uniprotkb:IGF-II mRNA-binding protein 3(gene name synonym)|uniprotkb:KH domain-containing protein overexpressed in cancer(gene name synonym)|uniprotkb:VICKZ family member 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000136231(gene)|ensembl:ENST00000258729(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007399"(nervous system development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_006538.2|interpro:IPR004087(K Homology)|dip:DIP-44171N|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034844|interpro:IPR035979|interpro:IPR036612|mint:O00425|rcsb pdb:2E44|rcsb pdb:6FQ1|rcsb pdb:6FQR|rcsb pdb:6GQE|rcsb pdb:6GX6|reactome:R-HSA-428359 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:yGEnYHFP+P05J45ZnHUdcPXHlQA9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q14103 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-299674|ensembl:ENSP00000313199|uniprotkb:P07029|uniprotkb:Q01858|uniprotkb:Q14100|uniprotkb:Q14101|uniprotkb:Q14102|uniprotkb:Q4W5A1|uniprotkb:A8K9J2|uniprotkb:Q9UCE8|uniprotkb:Q9UCE9 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpd_human(display_long)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000138668(gene)|ensembl:ENST00000313899(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021549"(cerebellum development)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:1901355"(response to rapamycin)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904383"(response to sodium phosphate)|go:"GO:1904586"(cellular response to putrescine)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990828"(hepatocyte dedifferentiation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR035979|mint:Q14103|rcsb pdb:1HD0|rcsb pdb:1HD1|rcsb pdb:1IQT|rcsb pdb:1WTB|rcsb pdb:1X0F|rcsb pdb:2Z5N|rcsb pdb:5IM0|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|reactome:R-HSA-450408|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:NP_001003810.1|refseq:NP_002129.2|refseq:NP_112737.1|refseq:NP_112738.1|dip:DIP-31163N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:LrC0nOpN6jGn3WELs5NEOccNPnw9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P11940 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q99878 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-6147676|uniprotkb:Q5JXQ5|uniprotkb:A2RUU6|ensembl:ENSP00000328484 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a1j_human(display_long)|uniprotkb:H2AC14(gene name)|psi-mi:H2AC14(display_short)|uniprotkb:H2AFE(gene name synonym)|uniprotkb:HIST1H2AJ(gene name synonym)|uniprotkb:Histone H2A/e(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_066544.1|ensembl:ENSG00000276368(gene)|ensembl:ENST00000333151(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:tS29VG3PpglHaYbu0w5z7pGvYyI9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P68371 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P31942 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-711437|uniprotkb:Q9NPI4|uniprotkb:Q9UFU4|uniprotkb:Q9Y4J5|uniprotkb:Q9BSX1|uniprotkb:Q9NP53|uniprotkb:Q9NP96|uniprotkb:Q9NPA7|ensembl:ENSP00000265866|uniprotkb:A8K682|uniprotkb:B3KRE1 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrh3_human(display_long)|uniprotkb:HNRNPH3(gene name)|psi-mi:HNRNPH3(display_short)|uniprotkb:HNRPH3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein 2H9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000096746(gene)|ensembl:ENST00000265866(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034969|interpro:IPR034970|interpro:IPR035979|mint:P31942|refseq:NP_036339.1|refseq:NP_067676.2|refseq:NP_001309363.1|refseq:NP_001309365.1|refseq:NP_001309366.1|refseq:NP_001309367.1|refseq:NP_001309368.1|refseq:NP_001309369.1|refseq:NP_001309370.1|refseq:NP_001309374.1|refseq:NP_001309375.1|refseq:NP_001309376.1|refseq:NP_001309377.1|refseq:NP_001309378.1|refseq:XP_016871657.1|refseq:XP_016871658.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:iJGBIhPXnQIIFQmgxWB1WjwVXSY9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P20671 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-4407441|uniprotkb:A0PK91|uniprotkb:P57754|uniprotkb:Q6FGY6|ensembl:ENSP00000341094 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a1d_human(display_long)|uniprotkb:H2AC7(gene name)|psi-mi:H2AC7(display_short)|uniprotkb:H2AFG(gene name synonym)|uniprotkb:HIST1H2AD(gene name synonym)|uniprotkb:Histone H2A.3(gene name synonym)|uniprotkb:Histone H2A/g(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_066409.1|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000196866(gene)|ensembl:ENST00000341023(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:5GT3|rcsb pdb:6KBB|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:Geraq+dGw3pvAAhgzzXQnYxDOOw9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:O43390 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-713419|uniprotkb:S4R3J4|uniprotkb:Q5TEH1|ensembl:ENSP00000304405|ensembl:ENSP00000363741|ensembl:ENSP00000489252|ensembl:ENSP00000489371|uniprotkb:Q9BV64|uniprotkb:Q2L7G6 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpr_human(display_long)|uniprotkb:HNRPR(gene name synonym)|uniprotkb:HNRNPR(gene name)|psi-mi:HNRNPR(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001095868.1|refseq:XP_005245768.1|ensembl:ENSG00000125944(gene)|ensembl:ENSG00000282958(gene)|ensembl:ENST00000302271(transcript)|ensembl:ENST00000374612(transcript)|ensembl:ENST00000634263(transcript)|ensembl:ENST00000634766(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043679"(axon terminus)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034411|interpro:IPR035979|mint:O43390|rcsb pdb:2DK2|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR041337|refseq:NP_005817.1|refseq:XP_011538773.1|refseq:NP_001284549.1|refseq:XP_016855497.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:UiOaRbnMd1S2FthR4RWltyq6xT49606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q9BTM1 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-4398590|uniprotkb:Q9NV63|ensembl:ENSP00000373730|ensembl:ENSP00000438553 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2aj_human(display_long)|uniprotkb:H2AJ(gene name)|psi-mi:H2AJ(display_short)|uniprotkb:H2AFJ(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_808760.1|ensembl:ENSG00000246705(gene)|ensembl:ENST00000389078(transcript)|ensembl:ENST00000544848(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:4EDU|rcsb pdb:6K60|rcsb pdb:6KVD|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-8939236 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:g6br63FeM17yJRfQI3GnmoM0vbc9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P46782 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-350569|uniprotkb:Q96BN0|uniprotkb:B2R4T2|ensembl:ENSP00000196551|ensembl:ENSP00000470114|ensembl:ENSP00000472985 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs5_human(display_long)|uniprotkb:RPS5(gene name)|psi-mi:RPS5(display_short)|uniprotkb:Small ribosomal subunit protein uS7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001000.2|rcsb pdb:6OLZ|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6Z6M|rcsb pdb:6XA1|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6Y0G|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:5FLX|rcsb pdb:6OLG|rcsb pdb:6OLI|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72706|ensembl:ENSG00000083845(gene)|ensembl:ENST00000196551(transcript)|ensembl:ENST00000596046(transcript)|ensembl:ENST00000601521(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000235(Ribosomal protein S7)|interpro:IPR005716(Ribosomal protein S7, eukaryotic/archaeal)|interpro:IPR020606|interpro:IPR023798|interpro:IPR036823|mint:P46782|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:5AJ0|reactome:R-HSA-72702 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:SoCJdf2InngZZtlz5qD1k5CEfEo9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P38159 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-743526|ensembl:ENSP00000359645|uniprotkb:Q5JQ67|uniprotkb:Q969R3|uniprotkb:D3DWH0|uniprotkb:E9PG86|uniprotkb:Q8N8Y7|uniprotkb:B4E3U4 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rbmx_human(display_long)|uniprotkb:Glycoprotein p43(gene name synonym)|uniprotkb:RBMX(gene name)|psi-mi:RBMX(display_short)|uniprotkb:HNRPG(gene name synonym)|uniprotkb:RBMXP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000147274(gene)|ensembl:ENST00000320676(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P38159|rcsb pdb:2MB0|rcsb pdb:2MKS|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_002130.2|refseq:NP_001158275.1|dip:DIP-34447N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:ocCkdy9PxjeVLUQf0tMVCEhFfO89606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P16989 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-358193|uniprotkb:Q14121|uniprotkb:Q969N6|uniprotkb:Q96B76|uniprotkb:B2RBW6|intact:EBI-2560381|ensembl:ENSP00000228251 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ybox3_human(display_long)|uniprotkb:YBX3(gene name)|psi-mi:YBX3(display_short)|uniprotkb:CSDA(gene name synonym)|uniprotkb:Cold shock domain-containing protein A(gene name synonym)|uniprotkb:DBPA(gene name synonym)|uniprotkb:DNA-binding protein A(gene name synonym)|uniprotkb:Single-strand DNA-binding protein NF-GMB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) go:"GO:0046622"(positive regulation of organ growth)|refseq:NP_001138898.1|refseq:NP_003642.3|dip:DIP-42489N|ensembl:ENSG00000060138(gene)|ensembl:ENST00000228251(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008584"(male gonad development)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031267"(small GTPase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:1902219"(negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1905538"(polysome binding)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P16989 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:cWuhmwOBWe5HdgPG1gyN7KzN4Rs9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P84090 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-711389|uniprotkb:P70659|uniprotkb:Q14259|ensembl:ENSP00000451080|uniprotkb:B2R5H2 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:erh_human(display_long)|uniprotkb:ERH(gene name)|psi-mi:ERH(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000100632(gene)|ensembl:ENST00000557016(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0030496"(midbody)|go:"GO:0034709"(methylosome)|interpro:IPR000781(Enhancer of rudimentary)|interpro:IPR035912|mint:P84090|rcsb pdb:1W9G|rcsb pdb:2NML|rcsb pdb:7CNC|refseq:NP_004441.1|dip:DIP-42473N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:foMOmvZ9wQyH0rrzBB2YlQhrT0g9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P43243 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-352602|ensembl:ENSP00000378284|ensembl:ENSP00000482895|uniprotkb:Q9UHW0|uniprotkb:Q9UQ27|uniprotkb:D3DQC3|uniprotkb:B7ZAV5 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:matr3_human(display_long)|uniprotkb:KIAA0723(gene name synonym)|uniprotkb:MATR3(gene name)|psi-mi:MATR3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000015479(gene)|ensembl:ENST00000394805(transcript)|ensembl:ENST00000618441(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:P43243|refseq:NP_001181883.1|refseq:NP_001181884.1|refseq:NP_061322.2|refseq:NP_954659.1|refseq:NP_001181885.1|refseq:NP_001269207.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:3UZlyCZHgdr1SBgUctv9Ev7XBSQ9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q08211 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-352022|intact:EBI-1058470|uniprotkb:Q5VY62|uniprotkb:Q6PD69|uniprotkb:Q99556|uniprotkb:B2RNV4|uniprotkb:Q05CI5|uniprotkb:Q12803|uniprotkb:Q32Q22|ensembl:ENSP00000356520 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:dhx9_human(display_long)|uniprotkb:DHX9(gene name)|psi-mi:DHX9(display_short)|uniprotkb:DDX9(gene name synonym)|uniprotkb:NDH2(gene name synonym)|uniprotkb:DExH-box helicase 9(gene name synonym)|uniprotkb:RNA helicase A(gene name synonym)|uniprotkb:LKP(gene name synonym)|uniprotkb:Nuclear DNA helicase II(gene name synonym)|uniprotkb:DEAH box protein 9(gene name synonym)|uniprotkb:Leukophysin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001348.2|dip:DIP-31504N|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033679"(3'-5' DNA/RNA helicase activity)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045142"(triplex DNA binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0097165"(nuclear stress granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1905172"(RISC complex binding)|go:"GO:1905538"(polysome binding)|go:"GO:1905698"(positive regulation of polysome binding)|go:"GO:1990518"(single-stranded 3'-5' DNA helicase activity)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000765"(regulation of cytoplasmic translation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR044445|interpro:IPR044446|interpro:IPR044447|mint:Q08211|rcsb pdb:3LLM|rcsb pdb:3VYX|rcsb pdb:3VYY|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-72163|go:"GO:1904973"(positive regulation of viral translation)|ensembl:ENSG00000135829(gene)|ensembl:ENST00000367549(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006260"(DNA replication)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0016604"(nuclear body) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:b0VP2Frtvwa9WbYVMwB6TbV2uGU9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:O00459 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-346930|uniprotkb:Q5EAT5|uniprotkb:Q9UPH9|intact:EBI-28974273|ensembl:ENSP00000222254 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:p85b_human(display_long)|uniprotkb:PIK3R2(gene name)|psi-mi:PIK3R2(display_short)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSP00000222254|refseq:NP_005018.1|dip:DIP-31811N|ensembl:ENSG00000105647(gene)|ensembl:ENST00000222254(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|rcsb pdb:6OX7|rcsb pdb:6U28|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-186763|reactome:R-HSA-198203|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|mint:O00459|rcsb pdb:2KT1|rcsb pdb:2XS6|rcsb pdb:3MTT|rcsb pdb:3O5Z|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-210993|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9013409 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:Ij0WS0eKPwShgFWQc7OEss7AcAU9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P12235 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-359074|uniprotkb:D3DP59|ensembl:ENSP00000281456 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:adt1_human(display_long)|uniprotkb:SLC25A4(gene name)|psi-mi:SLC25A4(display_short)|uniprotkb:ANT1(gene name synonym)|uniprotkb:Adenine nucleotide translocator 1(gene name synonym)|uniprotkb:ADP,ATP carrier protein 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 4(gene name synonym)|uniprotkb:ADP,ATP carrier protein, heart/skeletal muscle isoform T1(gene name synonym)|uniprotkb:AAC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001142.2|ensembl:ENST00000281456(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0015866"(ADP transport)|ensembl:ENSG00000151729(gene)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12235|reactome:R-HSA-1268020|reactome:R-HSA-180897|reactome:R-HSA-83936|dip:DIP-33116N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:vs4XIUUUypcIHR9Lz4j1buDAnjM9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q86V81 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-347640|uniprotkb:O43672 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:thoc4_human(display_long)|uniprotkb:ALYREF(gene name)|psi-mi:ALYREF(display_short)|uniprotkb:ALY(gene name synonym)|uniprotkb:Ally of AML-1 and LEF-1(gene name synonym)|uniprotkb:Aly/REF export factor(gene name synonym)|uniprotkb:BEF(gene name synonym)|uniprotkb:THOC4(gene name synonym)|uniprotkb:Transcriptional coactivator Aly/REF(gene name synonym)|uniprotkb:bZIP-enhancing factor BEF(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_005773.3|mint:Q86V81|dip:DIP-32711N|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0031297"(replication fork processing)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|rcsb pdb:3ULH|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR025715 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:beNqQmz9NZk8EdpXoQs0lIxOvTk9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:O14654 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-356594|ensembl:ENSP00000505547 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P23527 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-1642161|uniprotkb:Q3KPI7|uniprotkb:Q8TCV6|ensembl:ENSP00000477527 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2b1o_human(display_long)|uniprotkb:H2BC17(gene name)|psi-mi:H2BC17(display_short)|uniprotkb:H2B-clustered histone 17(gene name synonym)|uniprotkb:H2BFH(gene name synonym)|uniprotkb:H2BFN(gene name synonym)|uniprotkb:HIST1H2BO(gene name synonym)|uniprotkb:Histone H2B.2(gene name synonym)|uniprotkb:Histone H2B.n(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_003518.2|ensembl:ENSG00000274641(gene)|ensembl:ENST00000616182(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P23527|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:vetsoCf1s6GUePoGq1wMLwz8obg9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P06899 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-6150252|uniprotkb:B2R4J4|uniprotkb:O60816|ensembl:ENSP00000342886|ensembl:ENSP00000476136 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2b1j_human(display_long)|uniprotkb:H2BC11(gene name)|psi-mi:H2BC11(display_short)|uniprotkb:H2BFR(gene name synonym)|uniprotkb:HIST1H2BJ(gene name synonym)|uniprotkb:Histone H2B.1(gene name synonym)|uniprotkb:Histone H2B.r(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_066402.2|dip:DIP-421N|ensembl:ENSG00000124635(gene)|ensembl:ENST00000339812(transcript)|ensembl:ENST00000607124(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P06899|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WAA|rcsb pdb:3WTP|rcsb pdb:4CAY|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5FUG|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5VEY|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6YOV|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7K5X|rcsb pdb:3WA9|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:74GQlSjGG1Ez6Uog74VXPLryKBc9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:O43143 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-1237044|uniprotkb:Q9NQT7|ensembl:ENSP00000336741 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:dhx15_human(display_long)|uniprotkb:DHX15(gene name)|psi-mi:DHX15(display_short)|uniprotkb:DBP1(gene name synonym)|uniprotkb:DDX15(gene name synonym)|uniprotkb:DEAH box protein 15(gene name synonym)|uniprotkb:ATP-dependent RNA helicase #46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001349.2|dip:DIP-38211N|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR044756|mint:O43143|rcsb pdb:5XDR|rcsb pdb:6ID1|rcsb pdb:6SH6|rcsb pdb:6SH7|reactome:R-HSA-72163|ensembl:ENSG00000109606(gene)|ensembl:ENST00000336812(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0043279"(response to alkaloid) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:rOkQ5RG/3gc1/0Qcn5ANS6ImepY9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:O75569 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-713955|ensembl:ENSP00000318176|uniprotkb:Q53G24|uniprotkb:Q6X7T5|uniprotkb:Q8NDK4|uniprotkb:A8K3I6 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:prkra_human(display_long)|uniprotkb:Protein activator of the interferon-induced protein kinase(gene name synonym)|uniprotkb:PKR-associated protein X(gene name synonym)|uniprotkb:PKR-associating protein X(gene name synonym)|uniprotkb:HSD-14(orf name)|uniprotkb:PRKRA(gene name)|psi-mi:PRKRA(display_short)|uniprotkb:RAX(gene name synonym)|uniprotkb:PACT(gene name synonym)|uniprotkb:HSD14(orf name)|uniprotkb:Protein kinase, interferon-inducible double-stranded RNA-dependent activator(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006955"(immune response)|go:"GO:0008047"(enzyme activator activity)|ensembl:ENSG00000180228(gene)|ensembl:ENST00000325748(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR033363|interpro:IPR044465|interpro:IPR044466|interpro:IPR044467|mint:O75569|rcsb pdb:2DIX|reactome:R-HSA-203927|reactome:R-HSA-426486|refseq:NP_001132989.1|refseq:NP_001132990.1|refseq:NP_003681.1|dip:DIP-41809N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:tZfziopZlC+1d3De97G3kDY+Tog9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P46783 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-354442|uniprotkb:Q5TZC0|uniprotkb:B2R4E3|ensembl:ENSP00000481646|ensembl:ENSP00000494190|ensembl:ENSP00000494440|ensembl:ENSP00000497917 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs10_human(display_long)|uniprotkb:RPS10(gene name)|psi-mi:RPS10(display_short)|uniprotkb:Small ribosomal subunit protein eS10(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001005.1|refseq:NP_001190174.1|refseq:NP_001191020.1|ensembl:ENSG00000124614(gene)|ensembl:ENST00000464218(transcript)|ensembl:ENST00000467531(transcript)|ensembl:ENST00000621356(transcript)|ensembl:ENST00000648437(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR005326(Plectin/S10, N-terminal)|rcsb pdb:6G51|interpro:IPR036388|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|interpro:IPR037447|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|mint:P46783|rcsb pdb:4UG0|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:4V6X|rcsb pdb:6ZUO|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|rcsb pdb:5T2C|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:GWUAJh7s0w/ar/SOpx0hiIJOr2c9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q00839 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-351126|uniprotkb:O75507|uniprotkb:Q8N174|uniprotkb:Q96HY9|uniprotkb:Q9BQ09|ensembl:ENSP00000491215 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpu_human(display_long)|uniprotkb:HNRNPU(gene name)|psi-mi:HNRNPU(display_short)|uniprotkb:SAFA(gene name synonym)|uniprotkb:U21.1(gene name synonym)|uniprotkb:HNRPU(gene name synonym)|uniprotkb:p120(gene name synonym)|uniprotkb:pp120(gene name synonym)|uniprotkb:C1orf199(gene name synonym)|uniprotkb:GRIP120(gene name synonym)|uniprotkb:Nuclear p120 ribonucleoprotein(gene name synonym)|uniprotkb:Scaffold-attachment factor A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_004492.2|refseq:NP_114032.2|ensembl:ENSG00000153187(gene)|ensembl:ENST00000640218(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:1990498"(mitotic spindle microtubule)|go:"GO:0098577"(inactive sex chromosome)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR026745|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q00839|rcsb pdb:1ZRJ|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990280"(RNA localization to chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006396"(RNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008143"("poly(A) binding")|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0017130"("poly(C) RNA binding")|go:"GO:0030496"(midbody)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|refseq:XP_016856604.1|refseq:XP_016856605.1|refseq:XP_016856606.1|dip:DIP-684N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:n73PY0Vis+D5Iq0q77h5Ck2V4789606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q99729 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P35637 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-400434|uniprotkb:Q9H4A8|ensembl:ENSP00000254108 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:fus_human(display_long)|uniprotkb:FUS(gene name)|psi-mi:FUS(display_short)|uniprotkb:TLS(gene name synonym)|uniprotkb:Oncogene FUS(gene name synonym)|uniprotkb:Oncogene TLS(gene name synonym)|uniprotkb:Translocated in liposarcoma protein(gene name synonym)|uniprotkb:POMp75(gene name synonym)|uniprotkb:75 kDa DNA-pairing protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001164105.1|refseq:NP_004951.1|ensembl:ENSG00000089280(gene)|ensembl:ENST00000254108(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008380"(RNA splicing)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044327"(dendritic spine head)|go:"GO:0046872"(metal ion binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034459|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:P35637|rcsb pdb:2LA6|rcsb pdb:2LCW|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:5W3N|rcsb pdb:5XRR|rcsb pdb:5XSG|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:6BWZ|rcsb pdb:6BXV|rcsb pdb:6BZP|rcsb pdb:6G99|rcsb pdb:6GBM|rcsb pdb:6KJ1|rcsb pdb:6KJ2|rcsb pdb:6KJ3|rcsb pdb:6KJ4|rcsb pdb:6SNJ|rcsb pdb:6XFM|rcsb pdb:7CYL|reactome:R-HSA-72163|dip:DIP-29857N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:HUP4fGXQyJnm5CFTuwjTpiucZOc9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P42336 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-2116585|uniprotkb:Q14CW1|uniprotkb:Q99762|ensembl:ENSP00000263967 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pk3ca_human(display_long)|uniprotkb:Phosphoinositide-3-kinase catalytic alpha polypeptide(gene name synonym)|uniprotkb:Serine/threonine protein kinase PIK3CA(gene name synonym)|uniprotkb:PIK3CA(gene name)|psi-mi:PIK3CA(display_short)|uniprotkb:Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha(gene name synonym)|uniprotkb:Phosphoinositide 3-kinase alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:XP_011511196.1|refseq:XP_006713721.1|refseq:NP_006209.2|dip:DIP-42728N|ensembl:ENSG00000121879(gene)|ensembl:ENST00000263967(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001944"(vasculature development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0005944"(phosphatidylinositol 3-kinase complex, class IB)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006909"(phagocytosis)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030168"(platelet activation)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035004"(phosphatidylinositol 3-kinase activity)|go:"GO:0035005"(1-phosphatidylinositol-4-phosphate 3-kinase activity)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0038028"(insulin receptor signaling pathway via phosphatidylinositol 3-kinase)|go:"GO:0038084"(vascular endothelial growth factor signaling pathway)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0043276"(anoikis)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044029"(hypomethylation of CpG island)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046934"(phosphatidylinositol-4,5-bisphosphate 3-kinase activity)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110053"(regulation of actin filament organization)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR000341(Phosphoinositide 3-kinase, ras-binding)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR003113(Phosphatidylinositol 3-kinase, p85-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR029071|interpro:IPR035892|interpro:IPR036940|interpro:IPR037704|interpro:IPR042236|mint:P42336|rcsb pdb:2ENQ|rcsb pdb:2RD0|rcsb pdb:3HHM|rcsb pdb:3HIZ|rcsb pdb:3ZIM|rcsb pdb:4JPS|rcsb pdb:4L1B|rcsb pdb:4L23|rcsb pdb:4L2Y|rcsb pdb:4OVU|rcsb pdb:4OVV|rcsb pdb:4TUU|rcsb pdb:4TV3|rcsb pdb:4WAF|rcsb pdb:4YKN|rcsb pdb:4ZOP|rcsb pdb:5DXT|rcsb pdb:5FI4|rcsb pdb:5ITD|rcsb pdb:5SW8|rcsb pdb:5SWG|rcsb pdb:5SWO|rcsb pdb:5SWP|rcsb pdb:5SWR|rcsb pdb:5SWT|rcsb pdb:5SX8|rcsb pdb:5SX9|rcsb pdb:5SXA|rcsb pdb:5SXB|rcsb pdb:5SXC|rcsb pdb:5SXD|rcsb pdb:5SXE|rcsb pdb:5SXF|rcsb pdb:5SXI|rcsb pdb:5SXJ|rcsb pdb:5SXK|rcsb pdb:5UBR|rcsb pdb:5UK8|rcsb pdb:5UKJ|rcsb pdb:5UL1|rcsb pdb:5XGH|rcsb pdb:5XGI|rcsb pdb:5XGJ|rcsb pdb:6GVF|rcsb pdb:6GVG|rcsb pdb:6GVH|rcsb pdb:6GVI|rcsb pdb:6NCT|rcsb pdb:6OAC|rcsb pdb:6PYS|rcsb pdb:6VO7|rcsb pdb:7JIU|rcsb pdb:7K6M|rcsb pdb:7K6N|rcsb pdb:7K6O|rcsb pdb:7K71|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1236382|reactome:R-HSA-1250342|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-180292|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-1963642|reactome:R-HSA-198203|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654689|reactome:R-HSA-5654695|reactome:R-HSA-5654710|reactome:R-HSA-5654720|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-9009391|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9027276|reactome:R-HSA-9028335|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9603381|reactome:R-HSA-9607240|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|rcsb pdb:5DXH|reactome:R-HSA-9703465|reactome:R-HSA-9703648 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:YIZWt9VfCmyBCWYkqAEaMAEsl3w9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q13310 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-372844|uniprotkb:Q6P0N3|uniprotkb:B1ANQ8|ensembl:ENSP00000361948|intact:EBI-877641|uniprotkb:Q4VC03 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pabp4_human(display_long)|uniprotkb:PABPC4(gene name)|psi-mi:PABPC4(display_short)|uniprotkb:APP1(gene name synonym)|uniprotkb:PABP4(gene name synonym)|uniprotkb:"Inducible poly(A)-binding protein"(gene name synonym)|uniprotkb:Activated-platelet protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001129126.1|refseq:NP_003810.1|ensembl:ENSG00000090621(gene)|ensembl:ENST00000372857(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006412"(translation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0061515"(myeloid cell development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:Q13310|refseq:NP_001129125.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:u1qCM3o5X7jLIa1vyqFCIH7v01w9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q99877 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-744423|uniprotkb:Q494S8|uniprotkb:Q96FB7|uniprotkb:B2R5L4|ensembl:ENSP00000446031|ensembl:ENSP00000483903 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2b1n_human(display_long)|uniprotkb:H2BC15(gene name)|psi-mi:H2BC15(display_short)|uniprotkb:H2BFD(gene name synonym)|uniprotkb:HIST1H2BN(gene name synonym)|uniprotkb:Histone H2B.d(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_003511.1|ensembl:ENSG00000233822(gene)|ensembl:ENST00000449538(transcript)|ensembl:ENST00000612898(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:nGZETothwO57PuE11M5ogikaZkM9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P61981 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-359832|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q6FH52|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSP00000306330 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:1433g_human(display_long)|uniprotkb:YWHAG(gene name)|psi-mi:YWHAG(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_036611.2|ensembl:ENSG00000170027(gene)|ensembl:ENST00000307630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006605"(protein targeting)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61981|rcsb pdb:2B05|rcsb pdb:3UZD|rcsb pdb:4E2E|rcsb pdb:4J6S|rcsb pdb:4O46|rcsb pdb:5D3E|rcsb pdb:6A5S|rcsb pdb:6BYJ|rcsb pdb:6BYL|rcsb pdb:6BZD|rcsb pdb:6FEL|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y4K|rcsb pdb:6Y6B|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-9614399|dip:DIP-33406N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:u1cd71h0RPgTOEMrQVhOelsxWnM9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q9Y6M1 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-1024419|intact:EBI-1059063|intact:EBI-1237206|uniprotkb:A0A4Z0|uniprotkb:B3FTN2|uniprotkb:B3FTN3|uniprotkb:B3FTN4|ensembl:ENSP00000371634 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:if2b2_human(display_long)|uniprotkb:IGF-II mRNA-binding protein 2(gene name synonym)|uniprotkb:Hepatocellular carcinoma autoantigen p62(gene name synonym)|uniprotkb:VICKZ family member 2(gene name synonym)|uniprotkb:IGF2BP2(gene name)|psi-mi:IGF2BP2(display_short)|uniprotkb:IMP2(gene name synonym)|uniprotkb:VICKZ2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001278801.1|refseq:NP_001278802.1|refseq:NP_001278803.1|refseq:NP_001278804.1|refseq:NP_001007226.1|refseq:NP_006539.3|ensembl:ENSG00000073792(gene)|ensembl:ENST00000382199(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR028743|interpro:IPR034843|interpro:IPR035979|interpro:IPR036612|mint:Q9Y6M1|rcsb pdb:2CQH|rcsb pdb:6ROL|reactome:R-HSA-428359|dip:DIP-35539N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:k45UViReMAxCv2cu7+tx+auevQc9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q7L7L0 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-5325551|ensembl:ENSP00000355656|ensembl:ENSP00000493926|uniprotkb:B2R4S4 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a3_human(display_long)|uniprotkb:H2AW(gene name)|psi-mi:H2AW(display_short)|uniprotkb:HIST3H2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000181218(gene)|ensembl:ENSG00000284841(gene)|ensembl:ENST00000366695(transcript)|refseq:NP_254280.1|ensembl:ENST00000645741(transcript)|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-5689603|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q7L7L0|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000786"(nucleosome)|dip:DIP-48936N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:t0RdR1SmUtmwRjtCS3uTyLGqSUI9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q15717 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-374260|uniprotkb:Q9BTT1|ensembl:ENSP00000385269|ensembl:ENSP00000472197|intact:EBI-6190219|uniprotkb:B4DVB8|uniprotkb:Q53XN6 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:elav1_human(display_long)|uniprotkb:ELAVL1(gene name)|psi-mi:ELAVL1(display_short)|uniprotkb:HUR(gene name synonym)|uniprotkb:Hu-antigen R(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) go:"GO:0006606"(protein import into nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035198"(miRNA binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|ensembl:ENSG00000066044(gene)|ensembl:ENST00000407627(transcript)|ensembl:ENST00000596459(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|refseq:NP_001410.2|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR034996|interpro:IPR035979|mint:Q15717|rcsb pdb:3HI9|rcsb pdb:4ED5|rcsb pdb:4EGL|rcsb pdb:4FXV|rcsb pdb:5SZW|rcsb pdb:6G2K|rcsb pdb:6GC5|rcsb pdb:6GD1|rcsb pdb:6GD2|rcsb pdb:6GD3|reactome:R-HSA-450520|reactome:R-HSA-72163|dip:DIP-31291N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:PciL5KuvP+2aUUv9cv7gWScgbw89606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P25398 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-354542|uniprotkb:Q76M58|ensembl:ENSP00000230050 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs12_human(display_long)|uniprotkb:RPS12(gene name)|psi-mi:RPS12(display_short)|uniprotkb:Small ribosomal subunit protein eS12(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001007.2|ensembl:ENSG00000112306(gene)|ensembl:ENST00000230050(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR000530(Ribosomal protein S12e)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR029064|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72702|reactome:R-HSA-72695|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:80AIouzSdCvnLUSA7qsMp6naZ3g9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q13151 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-724092|ensembl:ENSP00000316042|intact:EBI-1043661|uniprotkb:Q6IB18 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:roa0_human(display_long)|uniprotkb:HNRPA0(gene name synonym)|uniprotkb:HNRNPA0(gene name)|psi-mi:HNRNPA0(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_006796.1|ensembl:ENSG00000177733(gene)|ensembl:ENST00000314940(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006954"(inflammatory response)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034801|interpro:IPR035979|mint:Q13151|reactome:R-HSA-72163|reactome:R-HSA-72203 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:buyQxR8FLxd4N6jRhwVsroeGrBw9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P67809 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:O60814 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-4409738|uniprotkb:A8K7P7|uniprotkb:Q2VPI7|ensembl:ENSP00000349430 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2b1k_human(display_long)|uniprotkb:H2BC12(gene name)|psi-mi:H2BC12(display_short)|uniprotkb:H2BFT(gene name synonym)|uniprotkb:HIRA-interacting protein 1(gene name synonym)|uniprotkb:HIRIP1(gene name synonym)|uniprotkb:HIST1H2BK(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_542160.1|refseq:NP_001299582.1|dip:DIP-48935N|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000197903(gene)|ensembl:ENST00000356950(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:O60814|rcsb pdb:2CV5|rcsb pdb:6KE9|rcsb pdb:6L9H|rcsb pdb:6LE9|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6V92|rcsb pdb:6Y5D|rcsb pdb:7BWD|rcsb pdb:7DBP|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:aBHcFUkMIdiiZov716H7kxmHzj09606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P62318 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-372789|uniprotkb:P43331|uniprotkb:B5BU13|uniprotkb:B4DJP7|ensembl:ENSP00000215829|intact:EBI-10981086 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:smd3_human(display_long)|uniprotkb:SNRPD3(gene name)|psi-mi:SNRPD3(display_short)|uniprotkb:snRNP core protein D3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_004166.1|refseq:NP_001265585.1|ensembl:ENSG00000100028(gene)|ensembl:ENST00000215829(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071208"(histone pre-mRNA DCP binding)|go:"GO:0071209"(U7 snRNA binding)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034099|mint:P62318|rcsb pdb:1D3B|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|rcsb pdb:7ABG|rcsb pdb:3VRI|rcsb pdb:4PJO|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:3PGW|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|dip:DIP-31216N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:WkrSZVfVmSQrJYfy7mwp48xjsVA9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P68104 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P12236 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-356254|ensembl:ENSP00000370808|uniprotkb:Q96C49 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000169100(gene)|ensembl:ENST00000381401(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|refseq:NP_001627.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q15366 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|uniprotkb:B4DXP5|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|ensembl:ENSP00000408949 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|dip:DIP-58934N|ensembl:ENSG00000197111(gene)|ensembl:ENST00000439930(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q92569 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-79893|intact:EBI-28975437|ensembl:ENSP00000262741|ensembl:ENSP00000361075|ensembl:ENSP00000412546|uniprotkb:O60482|uniprotkb:Q5T4P2|uniprotkb:B2R9C1|uniprotkb:Q5T4P1|uniprotkb:D3DQ12 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:p55g_human(display_long)|uniprotkb:Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma(gene name synonym)|uniprotkb:PIK3R3(gene name)|psi-mi:PIK3R3(display_short)|uniprotkb:p55PIK(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9670439|ensembl:ENSG00000117461(gene)|ensembl:ENST00000262741(transcript)|ensembl:ENST00000372006(transcript)|ensembl:ENST00000420542(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|interpro:IPR000980(SH2 motif)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR036860|mint:Q92569|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-2219530|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-512988|reactome:R-HSA-6811558|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|reactome:R-HSA-8853659|reactome:R-HSA-9009391|refseq:NP_001107644.1|refseq:NP_003620.3|ensembl:ENSP00000262741|ensembl:ENSP00000361075|ensembl:ENSP00000412546|ensembl:ENST00000423209|ensembl:ENSP00000391431|dip:DIP-30925N|refseq:NP_001290358.1|refseq:XP_016858103.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:oIVTuGRhg/Kn3h+Br1EfiAtiAQQ9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P04908 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:4Qno1mMYZB6FdNoojrzulWLVq849606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:P42338 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-2609540|uniprotkb:D3DNF0|uniprotkb:Q24JU2|ensembl:ENSP00000289153|ensembl:ENSP00000418143|ensembl:ENSP00000501150 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pk3cb_human(display_long)|uniprotkb:PIK3CB(gene name)|psi-mi:PIK3CB(display_short)|uniprotkb:PIK3C1(gene name synonym)|uniprotkb:Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_006210.1|refseq:XP_011511197.1|refseq:XP_005247587.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0006935"(chemotaxis)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0030168"(platelet activation)|go:"GO:0030496"(midbody)|go:"GO:0033031"(positive regulation of neutrophil apoptotic process)|go:"GO:0035004"(phosphatidylinositol 3-kinase activity)|go:"GO:0035005"(1-phosphatidylinositol-4-phosphate 3-kinase activity)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046934"(phosphatidylinositol-4,5-bisphosphate 3-kinase activity)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0070527"(platelet aggregation)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR000341(Phosphoinositide 3-kinase, ras-binding)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR003113(Phosphatidylinositol 3-kinase, p85-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR029071|interpro:IPR035892|interpro:IPR036940|interpro:IPR037702|interpro:IPR042236|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1660499|reactome:R-HSA-186763|reactome:R-HSA-198203|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8853659|reactome:R-HSA-9027276|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9673767|reactome:R-HSA-9673770|ensembl:ENSG00000051382(gene)|ensembl:ENST00000289153(transcript)|ensembl:ENST00000477593(transcript)|ensembl:ENST00000674063(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001952"(regulation of cell-matrix adhesion)|go:"GO:0002931"(response to ischemia)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|refseq:XP_006713722.1|refseq:XP_016862108.1|dip:DIP-44775N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:Nga6TlSCXWs2NVRR5XfxvnLfWUk9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:O15523 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-2462220|uniprotkb:Q8IYV7|uniprotkb:B4DK29|uniprotkb:B4DXX7|ensembl:ENSP00000336725|ensembl:ENSP00000353284 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ddx3y_human(display_long)|uniprotkb:DDX3Y(gene name)|psi-mi:DDX3Y(display_short)|uniprotkb:DBY(gene name synonym)|uniprotkb:DEAD box protein 3, Y-chromosomal(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001116137.1|refseq:NP_004651.2|refseq:NP_001289481.1|ensembl:ENSG00000067048(gene)|ensembl:ENST00000336079(transcript)|ensembl:ENST00000360160(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007276"(gamete generation)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O15523 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:dYhBr9Igq5eMq9U8g+c30nfdaKo9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O56264 uniprotkb:Q9H0D6 intact:EBI-6150240|uniprotkb:Q77XR5 intact:EBI-372110|uniprotkb:Q3L8N4|uniprotkb:Q6KGZ9|uniprotkb:Q9BQL1|uniprotkb:Q9NTW0|uniprotkb:Q9NXS6|uniprotkb:Q9UL53|ensembl:ENSP00000366396 psi-mi:ns1_i97a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:xrn2_human(display_long)|uniprotkb:XRN2(gene name)|psi-mi:XRN2(display_short)|uniprotkb:DHM1-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:130763(i97a1)|taxid:130763("Influenza A virus (strain A/Hong Kong/156/1997 H5N1 genotype Gs/Gd)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157161|imex:IM-17331-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_036387.2|refseq:NP_001304889.1|ensembl:ENSG00000088930(gene)|ensembl:ENST00000377191(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000738"(DNA catabolic process, exonucleolytic)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0016235"(aggresome)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|interpro:IPR004859(Putative 5-3 exonuclease)|interpro:IPR017151(5'-3' exoribonuclease 2)|interpro:IPR027073|interpro:IPR041412|mint:Q9H0D6|reactome:R-HSA-390471|reactome:R-HSA-6791226|dip:DIP-31166N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:PtWBGUKhfki5mWNVrfrW7CyGwKY130763 rogid:Ui0NiU+fGe68hK5CYTolkhioQbQ9606 intact-crc:A6B4A9673E05AF2D|rigid:8mJZhSyapY10vvCnJd21xpQ7owE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q00335 uniprotkb:P62805 intact:EBI-6150586|uniprotkb:Q8QT11 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:mu2_reovl(display_long)|uniprotkb:M1(gene name)|psi-mi:M1(display_short) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157491|imex:IM-17331-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012494(Reovirus minor core protein, Mu-2)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0044163"(host cytoskeleton) ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:SmkjW60yzahp2xrqULAWVql6r4o10884 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:51F59F5F85054BB3|rigid:AEcWv/nwc1Hm+HMHHekCXux2y3M false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q00335 uniprotkb:P49368 intact:EBI-6150586|uniprotkb:Q8QT11 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:mu2_reovl(display_long)|uniprotkb:M1(gene name)|psi-mi:M1(display_short) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157491|imex:IM-17331-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012494(Reovirus minor core protein, Mu-2)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0044163"(host cytoskeleton) refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:SmkjW60yzahp2xrqULAWVql6r4o10884 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:51F59F5F85054BB3|rigid:AEcWv/nwc1Hm+HMHHekCXux2y3M false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q00335 uniprotkb:Q8TDM6 intact:EBI-6150586|uniprotkb:Q8QT11 intact:EBI-715138|uniprotkb:Q149N1|uniprotkb:Q5T1H7|uniprotkb:Q5T1H8|uniprotkb:Q6DKG3|uniprotkb:Q86WC0|uniprotkb:Q8TDM7|uniprotkb:Q9UE73|uniprotkb:Q9Y4E3|uniprotkb:A6H8Y3|ensembl:ENSP00000361467|ensembl:ENSP00000484894 psi-mi:mu2_reovl(display_long)|uniprotkb:M1(gene name)|psi-mi:M1(display_short) psi-mi:dlg5_human(display_long)|uniprotkb:Placenta and prostate DLG(gene name synonym)|uniprotkb:Discs large protein P-dlg(gene name synonym)|uniprotkb:DLG5(gene name)|psi-mi:DLG5(display_short)|uniprotkb:KIAA0583(gene name synonym)|uniprotkb:PDLG(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157491|imex:IM-17331-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012494(Reovirus minor core protein, Mu-2)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0044163"(host cytoskeleton) refseq:NP_004738.3|refseq:XP_016872403.1|refseq:XP_011538647.1|ensembl:ENSG00000151208(gene)|ensembl:ENSG00000274429(gene)|ensembl:ENST00000372391(transcript)|ensembl:ENST00000614211(transcript)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|refseq:XP_006718119.1|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0030901"(midbrain development)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045176"(apical protein localization)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072205"(metanephric collecting duct development)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006907(Protein of unknown function DUF622)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR035537|interpro:IPR036028|interpro:IPR036034|mint:Q8TDM6|rcsb pdb:1UIT|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|dip:DIP-41450N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:SmkjW60yzahp2xrqULAWVql6r4o10884 rogid:UmBC3Fli9huOHBiaXBtfPogAQCE9606 intact-crc:51F59F5F85054BB3|rigid:AEcWv/nwc1Hm+HMHHekCXux2y3M false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q00335 uniprotkb:P48643 intact:EBI-6150586|uniprotkb:Q8QT11 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:mu2_reovl(display_long)|uniprotkb:M1(gene name)|psi-mi:M1(display_short) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157491|imex:IM-17331-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012494(Reovirus minor core protein, Mu-2)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0044163"(host cytoskeleton) refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:SmkjW60yzahp2xrqULAWVql6r4o10884 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:51F59F5F85054BB3|rigid:AEcWv/nwc1Hm+HMHHekCXux2y3M false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q00335 uniprotkb:Q5VTE0 intact:EBI-6150586|uniprotkb:Q8QT11 intact:EBI-877809 psi-mi:mu2_reovl(display_long)|uniprotkb:M1(gene name)|psi-mi:M1(display_short) psi-mi:ef1a3_human(display_long)|uniprotkb:EEF1A1P5(gene name)|psi-mi:EEF1A1P5(display_short)|uniprotkb:Eukaryotic elongation factor 1 A-like 3(gene name synonym)|uniprotkb:EEF1AL3(gene name synonym)|uniprotkb:Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157491|imex:IM-17331-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012494(Reovirus minor core protein, Mu-2)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0044163"(host cytoskeleton) go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR031157|reactome:R-HSA-156842|interpro:IPR027417 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:SmkjW60yzahp2xrqULAWVql6r4o10884 rogid:3t6tj3i+3CKTC1NsrHyBkeoRK789606 intact-crc:51F59F5F85054BB3|rigid:AEcWv/nwc1Hm+HMHHekCXux2y3M false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q00335 uniprotkb:P50991 intact:EBI-6150586|uniprotkb:Q8QT11 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:mu2_reovl(display_long)|uniprotkb:M1(gene name)|psi-mi:M1(display_short) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157491|imex:IM-17331-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012494(Reovirus minor core protein, Mu-2)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0044163"(host cytoskeleton) refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:SmkjW60yzahp2xrqULAWVql6r4o10884 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 intact-crc:51F59F5F85054BB3|rigid:AEcWv/nwc1Hm+HMHHekCXux2y3M false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q00335 uniprotkb:P40227 intact:EBI-6150586|uniprotkb:Q8QT11 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:mu2_reovl(display_long)|uniprotkb:M1(gene name)|psi-mi:M1(display_short) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157491|imex:IM-17331-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012494(Reovirus minor core protein, Mu-2)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0044163"(host cytoskeleton) refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:SmkjW60yzahp2xrqULAWVql6r4o10884 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 intact-crc:51F59F5F85054BB3|rigid:AEcWv/nwc1Hm+HMHHekCXux2y3M false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q00335 uniprotkb:P62280 intact:EBI-6150586|uniprotkb:Q8QT11 intact:EBI-1047710|uniprotkb:B2R4F5|uniprotkb:P04643|uniprotkb:Q498Y6|uniprotkb:Q6IRY0|ensembl:ENSP00000270625 psi-mi:mu2_reovl(display_long)|uniprotkb:M1(gene name)|psi-mi:M1(display_short) psi-mi:rs11_human(display_long)|uniprotkb:RPS11(gene name)|psi-mi:RPS11(display_short)|uniprotkb:Small ribosomal subunit protein uS17(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157491|imex:IM-17331-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012494(Reovirus minor core protein, Mu-2)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0044163"(host cytoskeleton) refseq:NP_001006.1|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000266(Ribosomal protein S17)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019979|interpro:IPR028333|interpro:IPR032440|mint:P62280|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|go:"GO:0005840"(ribosome)|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|ensembl:ENSG00000142534(gene)|ensembl:ENST00000270625(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6OM0|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:SmkjW60yzahp2xrqULAWVql6r4o10884 rogid:0fqJjtWAuz31VTKt2mbteRoi8vA9606 intact-crc:51F59F5F85054BB3|rigid:AEcWv/nwc1Hm+HMHHekCXux2y3M false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q00335 uniprotkb:Q9BQE3 intact:EBI-6150586|uniprotkb:Q8QT11 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:mu2_reovl(display_long)|uniprotkb:M1(gene name)|psi-mi:M1(display_short) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157491|imex:IM-17331-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012494(Reovirus minor core protein, Mu-2)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0044163"(host cytoskeleton) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:SmkjW60yzahp2xrqULAWVql6r4o10884 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:51F59F5F85054BB3|rigid:AEcWv/nwc1Hm+HMHHekCXux2y3M false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q00335 uniprotkb:Q71U36 intact:EBI-6150586|uniprotkb:Q8QT11 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:mu2_reovl(display_long)|uniprotkb:M1(gene name)|psi-mi:M1(display_short) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157491|imex:IM-17331-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012494(Reovirus minor core protein, Mu-2)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0044163"(host cytoskeleton) refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:SmkjW60yzahp2xrqULAWVql6r4o10884 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 intact-crc:51F59F5F85054BB3|rigid:AEcWv/nwc1Hm+HMHHekCXux2y3M false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q00335 uniprotkb:P68104 intact:EBI-6150586|uniprotkb:Q8QT11 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:mu2_reovl(display_long)|uniprotkb:M1(gene name)|psi-mi:M1(display_short) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157491|imex:IM-17331-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012494(Reovirus minor core protein, Mu-2)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0044163"(host cytoskeleton) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:SmkjW60yzahp2xrqULAWVql6r4o10884 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 intact-crc:51F59F5F85054BB3|rigid:AEcWv/nwc1Hm+HMHHekCXux2y3M false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q00335 uniprotkb:Q86SQ0 intact:EBI-6150586|uniprotkb:Q8QT11 intact:EBI-2798483|uniprotkb:Q68CY3|uniprotkb:Q8NCU5|uniprotkb:Q6NT98|uniprotkb:Q59EA8|uniprotkb:A5PKZ3|uniprotkb:Q8N8U8|uniprotkb:Q8NAB1|ensembl:ENSP00000377502|ensembl:ENSP00000405405 psi-mi:mu2_reovl(display_long)|uniprotkb:M1(gene name)|psi-mi:M1(display_short) psi-mi:phlb2_human(display_long)|uniprotkb:LL5B(gene name synonym)|uniprotkb:Protein LL5-beta(gene name synonym)|uniprotkb:PHLDB2(gene name)|psi-mi:PHLDB2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157491|imex:IM-17331-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012494(Reovirus minor core protein, Mu-2)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0044163"(host cytoskeleton) refseq:NP_001127909.1|refseq:NP_001127910.1|refseq:NP_001127911.1|refseq:NP_665696.1|ensembl:ENSG00000144824(gene)|ensembl:ENST00000393925(transcript)|ensembl:ENST00000431670(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0031252"(cell leading edge)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045180"(basal cortex)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045296"(cadherin binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:1904261"(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037810|go:"GO:1903690"(negative regulation of wound healing, spreading of epidermal cells)|dip:DIP-42196N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:SmkjW60yzahp2xrqULAWVql6r4o10884 rogid:T5YIJ7WjxQlZKWAd/28wh3Znui89606 intact-crc:51F59F5F85054BB3|rigid:AEcWv/nwc1Hm+HMHHekCXux2y3M false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q00335 uniprotkb:P42677 intact:EBI-6150586|uniprotkb:Q8QT11 intact:EBI-356336|ensembl:ENSP00000499044|uniprotkb:Q5T4L6 psi-mi:mu2_reovl(display_long)|uniprotkb:M1(gene name)|psi-mi:M1(display_short) psi-mi:rs27_human(display_long)|uniprotkb:RPS27(gene name)|psi-mi:RPS27(display_short)|uniprotkb:MPS1(gene name synonym)|uniprotkb:Metallopan-stimulin 1(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS27(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157491|imex:IM-17331-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012494(Reovirus minor core protein, Mu-2)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0044163"(host cytoskeleton) refseq:NP_001021.1|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|ensembl:ENSG00000177954(gene)|ensembl:ENST00000651669(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:P42677|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-141444|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-2500257|rcsb pdb:6OM7|reactome:R-HSA-5663220|reactome:R-HSA-6791226|reactome:R-HSA-68877|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-9648025|reactome:R-HSA-975956|reactome:R-HSA-975957|dip:DIP-44182N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:SmkjW60yzahp2xrqULAWVql6r4o10884 rogid:OA5IWAJDBpY5FFdVnun7Sq/jI7g9606 intact-crc:51F59F5F85054BB3|rigid:AEcWv/nwc1Hm+HMHHekCXux2y3M false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q00335 uniprotkb:Q6ZU67 intact:EBI-6150586|uniprotkb:Q8QT11 intact:EBI-6150593|uniprotkb:A1A5D7|uniprotkb:A1A5D6|uniprotkb:Q58A27|uniprotkb:Q58A26|uniprotkb:C9JQZ5|ensembl:ENSP00000421169 psi-mi:mu2_reovl(display_long)|uniprotkb:M1(gene name)|psi-mi:M1(display_short) psi-mi:bend4_human(display_long)|uniprotkb:BEND4(gene name)|psi-mi:BEND4(display_short)|uniprotkb:CCDC4(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157491|imex:IM-17331-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012494(Reovirus minor core protein, Mu-2)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0044163"(host cytoskeleton) refseq:NP_001153019.1|refseq:NP_997289.2|refseq:XP_016863674.1|ensembl:ENSG00000188848(gene)|ensembl:ENST00000502486(transcript)|interpro:IPR018379|interpro:IPR038950 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:SmkjW60yzahp2xrqULAWVql6r4o10884 rogid:vivbaUqGrhStJLehVpnn+JRib8k9606 intact-crc:51F59F5F85054BB3|rigid:AEcWv/nwc1Hm+HMHHekCXux2y3M false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q00335 uniprotkb:P07437 intact:EBI-6150586|uniprotkb:Q8QT11 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:mu2_reovl(display_long)|uniprotkb:M1(gene name)|psi-mi:M1(display_short) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157491|imex:IM-17331-44 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR012494(Reovirus minor core protein, Mu-2)|go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0044163"(host cytoskeleton) refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:SmkjW60yzahp2xrqULAWVql6r4o10884 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:51F59F5F85054BB3|rigid:AEcWv/nwc1Hm+HMHHekCXux2y3M false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O55777 uniprotkb:Q02539 intact:EBI-6150653 intact:EBI-932603|uniprotkb:Q3MJ34|ensembl:ENSP00000244573 psi-mi:v_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h11_human(display_long)|uniprotkb:H1-1(gene name)|psi-mi:H1-1(display_short)|uniprotkb:H1F1(gene name synonym)|uniprotkb:HIST1H1A(gene name synonym)|uniprotkb:Histone H1a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157542|imex:IM-17331-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|refseq:NP_047108.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_005316.1|ensembl:ENSG00000124610(gene)|ensembl:ENST00000244573(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q02539|reactome:R-HSA-140342|reactome:R-HSA-2559584 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:cygnm+WurCfFkldzbOmiGHXlsI4928303 rogid:4u8P8jFM3onWx43+SxL320urjhk9606 intact-crc:88732BE7586BDF46|rigid:Y+uD3lXB9tD1j99CWyg/ASZIUeU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O55777 uniprotkb:P52630 intact:EBI-6150653 intact:EBI-1546963|uniprotkb:Q16430|uniprotkb:Q16431|uniprotkb:Q9UDL4|intact:EBI-10989287|uniprotkb:B4DLC7|uniprotkb:G3V2M6|ensembl:ENSP00000315768 psi-mi:v_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:stat2_human(display_long)|uniprotkb:p113(gene name synonym)|uniprotkb:STAT2(gene name)|psi-mi:STAT2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157542|imex:IM-17331-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|refseq:NP_047108.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_005410.1|refseq:NP_938146.1|dip:DIP-38511N|ensembl:ENSG00000170581(gene)|ensembl:ENST00000314128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0090140"(regulation of mitochondrial fission)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022756|interpro:IPR035854|interpro:IPR036535|interpro:IPR036860|mint:P52630|rcsb pdb:2KA4|rcsb pdb:6UX2|rcsb pdb:6WCZ|reactome:R-HSA-8854691|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9679191 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:cygnm+WurCfFkldzbOmiGHXlsI4928303 rogid:uA0lxm5vmrLClQRP7NItd0/u4Ko9606 intact-crc:88732BE7586BDF46|rigid:Y+uD3lXB9tD1j99CWyg/ASZIUeU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O55777 uniprotkb:P42224 intact:EBI-6150653 intact:EBI-1057697|uniprotkb:Q53S88|uniprotkb:Q53XW4|uniprotkb:B2RCA0|uniprotkb:Q9UDL5|uniprotkb:A8K989|uniprotkb:D2KFR8|uniprotkb:Q68D00|uniprotkb:D3DPI7|ensembl:ENSP00000354394|ensembl:ENSP00000386244|ensembl:ENSP00000388240|ensembl:ENSP00000438703 psi-mi:v_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:stat1_human(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)|uniprotkb:Transcription factor ISGF-3 components p91/p84(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157542|imex:IM-17331-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|refseq:NP_047108.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_009330.1|refseq:NP_644671.1|rcsb pdb:1YVL|rcsb pdb:2KA6|rcsb pdb:3WWT|reactome:R-HSA-1059683|reactome:R-HSA-1169408|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8939902|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9013508|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-909733|rcsb pdb:1BF5|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-912694|refseq:XP_006712781.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016922"(nuclear receptor binding)|ensembl:ENSG00000115415(gene)|ensembl:ENST00000361099(transcript)|ensembl:ENST00000409465(transcript)|ensembl:ENST00000415035(transcript)|ensembl:ENST00000540176(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051607"(defense response to virus)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0061326"(renal tubule development)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022752|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|interpro:IPR035859|interpro:IPR036535|interpro:IPR036860|interpro:IPR038295|mint:P42224|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042393"(histone binding)|dip:DIP-46140N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:cygnm+WurCfFkldzbOmiGHXlsI4928303 rogid:a2ZnhdFZkctbjaXLpsYNJ3q5Cv49606 intact-crc:88732BE7586BDF46|rigid:Y+uD3lXB9tD1j99CWyg/ASZIUeU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O55777 uniprotkb:P22492 intact:EBI-6150653 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 psi-mi:v_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157542|imex:IM-17331-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|refseq:NP_047108.1|interpro:IPR025909|interpro:IPR035430|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0046872"(metal ion binding) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:cygnm+WurCfFkldzbOmiGHXlsI4928303 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 intact-crc:88732BE7586BDF46|rigid:Y+uD3lXB9tD1j99CWyg/ASZIUeU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q9HCE1 intact:EBI-6150681 intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028|ensembl:ENSP00000358659|ensembl:ENSP00000399797 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|refseq:NP_001308253.1|ensembl:ENSG00000155363(gene)|ensembl:ENST00000357443(transcript)|ensembl:ENST00000369645(transcript)|ensembl:ENST00000413052(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043186"(P granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041679|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-8936459|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P62854 intact:EBI-6150681 intact:EBI-353438|uniprotkb:P02383|uniprotkb:Q3MHD8|uniprotkb:P70394|uniprotkb:Q06722|uniprotkb:Q6IRY4|ensembl:ENSP00000348849|ensembl:ENSP00000450339|ensembl:ENSP00000496643 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rs26_human(display_long)|uniprotkb:RPS26(gene name)|psi-mi:RPS26(display_short)|uniprotkb:Small ribosomal subunit protein eS26(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001020.2|refseq:XP_005276741.1|rcsb pdb:6OLG|rcsb pdb:6OLF|ensembl:ENST00000356464(transcript)|ensembl:ENST00000552361(transcript)|ensembl:ENST00000646449(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000892(Ribosomal protein S26e)|interpro:IPR038551|mint:P62854|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6G5H|ensembl:ENSG00000197728(gene)|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-156827 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:bo2ruYMNjjLCMo/kwAWzmlJrrjU9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q99879 intact:EBI-6150681 intact:EBI-3893474|uniprotkb:Q6NWQ3|ensembl:ENSP00000477907 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h2b1m_human(display_long)|uniprotkb:H2BC14(gene name)|psi-mi:H2BC14(display_short)|uniprotkb:H2BFE(gene name synonym)|uniprotkb:HIST1H2BM(gene name synonym)|uniprotkb:Histone H2B.e(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_003512.1|ensembl:ENSG00000273703(gene)|ensembl:ENST00000621112(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-912446|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:ETy0Ge+X/+GWAlBGq+YpQLc+DoE9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P58876 intact:EBI-6150681 intact:EBI-4409942|ensembl:ENSP00000289316|ensembl:ENSP00000367008 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h2b1d_human(display_long)|uniprotkb:Histone H2B.b(gene name synonym)|uniprotkb:H2BC5(gene name)|psi-mi:H2BC5(display_short)|uniprotkb:H2B-clustered histone 5(gene name synonym)|uniprotkb:H2BFB(gene name synonym)|uniprotkb:HIRA-interacting protein 2(gene name synonym)|uniprotkb:HIRIP2(gene name synonym)|uniprotkb:HIST1H2BD(gene name synonym)|uniprotkb:Histone H2B.1 B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_066407.1|refseq:NP_619790.1|ensembl:ENSG00000158373(gene)|ensembl:ENST00000289316(transcript)|ensembl:ENST00000377777(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P58876|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005634"(nucleus) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:07VBw5MCphdkMydMOPSjVqpGriI9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q08211 intact:EBI-6150681 intact:EBI-352022|intact:EBI-1058470|uniprotkb:Q5VY62|uniprotkb:Q6PD69|uniprotkb:Q99556|uniprotkb:B2RNV4|uniprotkb:Q05CI5|uniprotkb:Q12803|uniprotkb:Q32Q22|ensembl:ENSP00000356520 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:dhx9_human(display_long)|uniprotkb:DHX9(gene name)|psi-mi:DHX9(display_short)|uniprotkb:DDX9(gene name synonym)|uniprotkb:NDH2(gene name synonym)|uniprotkb:DExH-box helicase 9(gene name synonym)|uniprotkb:RNA helicase A(gene name synonym)|uniprotkb:LKP(gene name synonym)|uniprotkb:Nuclear DNA helicase II(gene name synonym)|uniprotkb:DEAH box protein 9(gene name synonym)|uniprotkb:Leukophysin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001348.2|dip:DIP-31504N|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033679"(3'-5' DNA/RNA helicase activity)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045142"(triplex DNA binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0097165"(nuclear stress granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1905172"(RISC complex binding)|go:"GO:1905538"(polysome binding)|go:"GO:1905698"(positive regulation of polysome binding)|go:"GO:1990518"(single-stranded 3'-5' DNA helicase activity)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000765"(regulation of cytoplasmic translation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR044445|interpro:IPR044446|interpro:IPR044447|mint:Q08211|rcsb pdb:3LLM|rcsb pdb:3VYX|rcsb pdb:3VYY|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-72163|go:"GO:1904973"(positive regulation of viral translation)|ensembl:ENSG00000135829(gene)|ensembl:ENST00000367549(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006260"(DNA replication)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0016604"(nuclear body) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:b0VP2Frtvwa9WbYVMwB6TbV2uGU9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P00338 intact:EBI-6150681 intact:EBI-372327|uniprotkb:Q53G53|uniprotkb:Q6IBM7|uniprotkb:Q6ZNV1|ensembl:ENSP00000368722|ensembl:ENSP00000395337|ensembl:ENSP00000445331|ensembl:ENSP00000499898|ensembl:ENSP00000499977|ensembl:ENSP00000500953|uniprotkb:Q9UDE8|uniprotkb:Q9UDE9|uniprotkb:D3DQY3|uniprotkb:B7Z5E3|uniprotkb:B4DKQ2|uniprotkb:F8W819 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:ldha_human(display_long)|uniprotkb:LDHA(gene name)|psi-mi:LDHA(display_short)|uniprotkb:LDH muscle subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-59(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 19 protein(gene name synonym)|uniprotkb:PIG19(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001158886.1|ensembl:ENSG00000134333(gene)|ensembl:ENSG00000288299(gene)|ensembl:ENST00000379412(transcript)|ensembl:ENST00000422447(transcript)|ensembl:ENST00000542179(transcript)|ensembl:ENST00000671981(transcript)|ensembl:ENST00000672405(transcript)|ensembl:ENST00000673204(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0009749"(response to glucose)|go:"GO:0016020"(membrane)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045296"(cadherin binding)|go:"GO:0048569"(post-embryonic animal organ development)|go:"GO:0051287"(NAD binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|rcsb pdb:1I10|mint:P00338|rcsb pdb:4AJP|rcsb pdb:4JNK|rcsb pdb:4L4R|rcsb pdb:4L4S|rcsb pdb:4M49|rcsb pdb:4OJN|rcsb pdb:4OKN|rcsb pdb:4QO7|rcsb pdb:4QO8|rcsb pdb:4QSM|rcsb pdb:4QT0|rcsb pdb:4R68|rcsb pdb:4R69|rcsb pdb:4RLS|rcsb pdb:4ZVV|rcsb pdb:5IXS|rcsb pdb:5IXY|rcsb pdb:5W8H|rcsb pdb:5W8I|rcsb pdb:5W8J|rcsb pdb:5W8K|rcsb pdb:5W8L|rcsb pdb:5ZJD|rcsb pdb:5ZJE|rcsb pdb:5ZJF|rcsb pdb:6BAD|rcsb pdb:6BAG|rcsb pdb:6BAX|rcsb pdb:6BAZ|rcsb pdb:6BB0|rcsb pdb:6BB1|rcsb pdb:6BB2|rcsb pdb:6BB3|rcsb pdb:6MV8|rcsb pdb:6MVA|rcsb pdb:6Q0D|rcsb pdb:6SBU|rcsb pdb:6SBV|rcsb pdb:6ZZR|reactome:R-HSA-70268|rcsb pdb:6Q13|refseq:NP_001158887.1|refseq:NP_005557.1|refseq:NP_001128711.1|refseq:NP_001158888.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:Zpq2lAJLPG+q2bMEru3cq7B5gCk9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P05386 intact:EBI-6150681 intact:EBI-354582|uniprotkb:A6NIB2|ensembl:ENSP00000346037 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rla1_human(display_long)|uniprotkb:RPLP1(gene name)|psi-mi:RPLP1(display_short)|uniprotkb:RRP1(gene name synonym)|uniprotkb:Large ribosomal subunit protein P1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_000994.1|refseq:NP_998890.1|ensembl:ENSG00000137818(gene)|ensembl:ENST00000260379(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR027534|interpro:IPR038716|mint:P05386|rcsb pdb:2LBF|rcsb pdb:4BEH|rcsb pdb:4V6X|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:rHSXz4ZCJy+JH6OrjUgHiTK85mo9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P39019 intact:EBI-6150681 intact:EBI-354451|ensembl:ENSP00000469228|ensembl:ENSP00000470004|ensembl:ENSP00000470972 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rs19_human(display_long)|uniprotkb:RPS19(gene name)|psi-mi:RPS19(display_short)|uniprotkb:Small ribosomal subunit protein eS19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001013.1|ensembl:ENSG00000105372(gene)|ensembl:ENST00000593863(transcript)|ensembl:ENST00000598742(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003723"(RNA binding)|ensembl:ENST00000600467(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0007000"(nucleolus organization)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060265"(positive regulation of respiratory burst involved in inflammatory response)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001266(Ribosomal protein S19e)|interpro:IPR018277|interpro:IPR036388|interpro:IPR036390|mint:P39019|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001308412.1|refseq:NP_001308413.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:3YqdJJJG+2nqoBf3PLu1fs7pVkY9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q5VTE0 intact:EBI-6150681 intact:EBI-877809 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:ef1a3_human(display_long)|uniprotkb:EEF1A1P5(gene name)|psi-mi:EEF1A1P5(display_short)|uniprotkb:Eukaryotic elongation factor 1 A-like 3(gene name synonym)|uniprotkb:EEF1AL3(gene name synonym)|uniprotkb:Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR031157|reactome:R-HSA-156842|interpro:IPR027417 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:3t6tj3i+3CKTC1NsrHyBkeoRK789606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P12277 intact:EBI-6150681 intact:EBI-357706|uniprotkb:Q2LE07|uniprotkb:A8K236|uniprotkb:B2R5R4|uniprotkb:Q6FG40|uniprotkb:Q9UC66|ensembl:ENSP00000299198 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:kcrb_human(display_long)|uniprotkb:CKB(gene name)|psi-mi:CKB(display_short)|uniprotkb:CKBB(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:Brain creatine kinase(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001814.2|go:"GO:0005829"(cytosol)|ensembl:ENSG00000166165(gene)|ensembl:ENST00000348956(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12277|rcsb pdb:3B6R|rcsb pdb:3DRB|rcsb pdb:3DRE|rcsb pdb:6V9H|go:"GO:0021762"(substantia nigra development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|reactome:R-HSA-71288|reactome:R-HSA-9696264|dip:DIP-52968N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:WLRnU8sRUfJQoaPY0edGi9xiR+g9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P62805 intact:EBI-6150681 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P46781 intact:EBI-6150681 intact:EBI-351206|uniprotkb:Q4QRK7|uniprotkb:Q9BVZ0|ensembl:ENSP00000302896|ensembl:ENSP00000375632|ensembl:ENSP00000375633|ensembl:ENSP00000478449|ensembl:ENSP00000479917|ensembl:ENSP00000480135|ensembl:ENSP00000480662|ensembl:ENSP00000481194|ensembl:ENSP00000481553|ensembl:ENSP00000481655|ensembl:ENSP00000481764|ensembl:ENSP00000481822|ensembl:ENSP00000482023|ensembl:ENSP00000482274|ensembl:ENSP00000482338|ensembl:ENSP00000482475|ensembl:ENSP00000483179|ensembl:ENSP00000484394|uniprotkb:A9C4C1 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rs9_human(display_long)|uniprotkb:RPS9(gene name)|psi-mi:RPS9(display_short)|uniprotkb:Small ribosomal subunit protein uS4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001004.2|refseq:NP_001308630.1|refseq:NP_001308631.1|refseq:NP_001308633.1|ensembl:ENSG00000170889(gene)|ensembl:ENSG00000274005(gene)|ensembl:ENSG00000274626(gene)|ensembl:ENSG00000274646(gene)|ensembl:ENSG00000274950(gene)|ensembl:ENSG00000275323(gene)|ensembl:ENSG00000277079(gene)|ensembl:ENSG00000277359(gene)|ensembl:ENSG00000278081(gene)|ensembl:ENSG00000278270(gene)|ensembl:ENST00000302907(transcript)|ensembl:ENST00000391752(transcript)|ensembl:ENST00000391753(transcript)|ensembl:ENST00000610826(transcript)|ensembl:ENST00000610953(transcript)|ensembl:ENST00000611921(transcript)|ensembl:ENST00000614737(transcript)|ensembl:ENST00000615346(transcript)|ensembl:ENST00000616082(transcript)|ensembl:ENST00000616536(transcript)|ensembl:ENST00000616839(transcript)|ensembl:ENST00000616877(transcript)|ensembl:ENST00000616928(transcript)|ensembl:ENST00000617291(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000618751(transcript)|go:"GO:0005829"(cytosol)|ensembl:ENST00000619229(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|ensembl:ENST00000620720(transcript)|ensembl:ENST00000620940(transcript)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR001912(Ribosomal protein S4)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005710(Ribosomal protein S4/S9, eukaryotic/archaeal)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|interpro:IPR018079|interpro:IPR022801|interpro:IPR036986|mint:P46781|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|go:"GO:0005634"(nucleus)|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|go:"GO:0005654"(nucleoplasm)|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:PGNjkKMs8bMMOSOz2AQvwuCvO1A9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q07020 intact:EBI-6150681 intact:EBI-352694|intact:EBI-8456577|intact:MINT-8429255|uniprotkb:F8VWC5|uniprotkb:Q8WTZ6|ensembl:ENSP00000447001 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl18_human(display_long)|uniprotkb:RPL18(gene name)|psi-mi:RPL18(display_short)|uniprotkb:Large ribosomal subunit protein eL18(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_000970.1|ensembl:ENSG00000063177(gene)|ensembl:ENST00000549920(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR000039(Ribosomal protein L18e)|interpro:IPR021131|interpro:IPR021132|interpro:IPR036227|mint:Q07020|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001257419.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:GgzBcLEQgBqbApFlaQIU2jktkAE9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P30050 intact:EBI-6150681 intact:EBI-352743|uniprotkb:Q6PB27|uniprotkb:Q5VVV2|ensembl:ENSP00000354739 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl12_human(display_long)|uniprotkb:RPL12(gene name)|psi-mi:RPL12(display_short)|uniprotkb:Large ribosomal subunit protein uL11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_000967.1|ensembl:ENSG00000197958(gene)|ensembl:ENST00000361436(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|interpro:IPR000911(Ribosomal protein L11)|interpro:IPR020783|interpro:IPR020784|interpro:IPR020785|interpro:IPR036769|interpro:IPR036796|mint:P30050|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:TNPEtl60cILofaPzUznvZiw6D7E9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P46779 intact:EBI-6150681 intact:EBI-366357|uniprotkb:Q6IAY0|uniprotkb:Q96FX1|uniprotkb:Q9BWQ0|uniprotkb:B2R4A6|uniprotkb:B4DEP9|uniprotkb:E9PB24|uniprotkb:C9JB50|uniprotkb:G5E9L2|ensembl:ENSP00000342787|ensembl:ENSP00000453319 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl28_human(display_long)|uniprotkb:RPL28(gene name)|psi-mi:RPL28(display_short)|uniprotkb:Large ribosomal subunit protein eL28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001129608.1|refseq:NP_001129609.1|refseq:NP_000982.2|refseq:NP_001129606.1|refseq:NP_001129607.1|ensembl:ENSG00000108107(gene)|ensembl:ENST00000344063(transcript)|ensembl:ENST00000559463(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002672(Ribosomal protein L28e)|interpro:IPR029004|mint:P46779|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:I7Me1zjfxk98g6C2NoYOWlmrYVc9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P68431 intact:EBI-6150681 intact:EBI-79722|ensembl:ENSP00000352252|ensembl:ENSP00000358160|ensembl:ENSP00000366999|ensembl:ENSP00000480826|ensembl:ENSP00000482271|ensembl:ENSP00000483283|ensembl:ENSP00000484095|ensembl:ENSP00000484638|ensembl:ENSP00000484658|ensembl:ENSP00000484841|ensembl:ENSP00000489282|intact:EBI-1560041|uniprotkb:A0PJT7|uniprotkb:P02295|uniprotkb:P02296|uniprotkb:P16106|uniprotkb:Q6ISV8|uniprotkb:Q6NWP8|uniprotkb:Q6NWP9|uniprotkb:Q6NXU4|uniprotkb:Q71DJ3|uniprotkb:Q93081|uniprotkb:A5PLR1 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h31_human(display_long)|uniprotkb:H3FA(gene name synonym)|uniprotkb:H3FL(gene name synonym)|uniprotkb:H3FD(gene name synonym)|uniprotkb:H3FI(gene name synonym)|uniprotkb:H3FH(gene name synonym)|uniprotkb:H3FK(gene name synonym)|uniprotkb:H3FF(gene name synonym)|uniprotkb:H3FJ(gene name synonym)|uniprotkb:H3FB(gene name synonym)|uniprotkb:Histone H3/a(gene name synonym)|uniprotkb:Histone H3/b(gene name synonym)|uniprotkb:Histone H3/c(gene name synonym)|uniprotkb:Histone H3/d(gene name synonym)|uniprotkb:Histone H3/f(gene name synonym)|uniprotkb:Histone H3/h(gene name synonym)|uniprotkb:Histone H3/i(gene name synonym)|uniprotkb:Histone H3/j(gene name synonym)|uniprotkb:Histone H3/k(gene name synonym)|uniprotkb:Histone H3/l(gene name synonym)|uniprotkb:H3C1(gene name)|psi-mi:H3C1(display_short)|uniprotkb:HIST1H3A(gene name synonym)|uniprotkb:H3C2(gene name)|psi-mi:H3C2(display_short)|uniprotkb:HIST1H3B(gene name synonym)|uniprotkb:H3C3(gene name)|psi-mi:H3C3(display_short)|uniprotkb:H3FC HIST1H3C(gene name synonym)|uniprotkb:H3C4(gene name)|psi-mi:H3C4(display_short)|uniprotkb:HIST1H3D(gene name synonym)|uniprotkb:H3C6(gene name)|psi-mi:H3C6(display_short)|uniprotkb:HIST1H3E(gene name synonym)|uniprotkb:H3C7(gene name)|psi-mi:H3C7(display_short)|uniprotkb:HIST1H3F(gene name synonym)|uniprotkb:H3C8(gene name)|psi-mi:H3C8(display_short)|uniprotkb:HIST1H3G(gene name synonym)|uniprotkb:H3C10(gene name)|psi-mi:H3C10(display_short)|uniprotkb:HIST1H3H(gene name synonym)|uniprotkb:H3C11(gene name)|psi-mi:H3C11(display_short)|uniprotkb:HIST1H3I(gene name synonym)|uniprotkb:H3C12(gene name)|psi-mi:H3C12(display_short)|uniprotkb:HIST1H3J(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) rcsb pdb:4TN7|rcsb pdb:4U68|rcsb pdb:4UP0|rcsb pdb:4UY4|rcsb pdb:4X3K|rcsb pdb:4Y6L|rcsb pdb:4YHP|rcsb pdb:4YHZ|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z0R|rcsb pdb:4Z2M|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:4QBS|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B31|rcsb pdb:5C11|rcsb pdb:5C13|rcsb pdb:5C3I|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5D6Y|rcsb pdb:5DAH|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5FFV|rcsb pdb:5GH9|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5HJB|rcsb pdb:5HJC|rcsb pdb:5HJD|rcsb pdb:5HYN|rcsb pdb:5IQL|rcsb pdb:5J3V|rcsb pdb:5J9S|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5B2J|rcsb pdb:5JRG|rcsb pdb:5KJH|rcsb pdb:5KJI|rcsb pdb:5KKL|rcsb pdb:5LUG|rcsb pdb:5M5G|rcsb pdb:5MR8|rcsb pdb:5NNC|rcsb pdb:5OY3|rcsb pdb:5SVX|rcsb pdb:5SVY|rcsb pdb:5SZB|rcsb pdb:5SZC|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5T1G|rcsb pdb:5T1I|rcsb pdb:5T8R|rcsb pdb:5TBN|rcsb pdb:5TDR|rcsb pdb:5TDW|rcsb pdb:5U2J|rcsb pdb:5V21|rcsb pdb:5V22|rcsb pdb:5VA6|rcsb pdb:5VAB|rcsb pdb:5VGE|rcsb pdb:5VNB|rcsb pdb:5NND|rcsb pdb:5WLE|rcsb pdb:5WVO|rcsb pdb:5WXG|rcsb pdb:5WXH|rcsb pdb:5WYI|rcsb pdb:5X60|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5XFQ|rcsb pdb:5XFR|rcsb pdb:5XNV|rcsb pdb:5XTZ|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Y20|rcsb pdb:5Y2F|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:6AXJ|rcsb pdb:6AZE|rcsb pdb:6BHD|rcsb pdb:6BHE|rcsb pdb:6BHG|rcsb pdb:6BHH|rcsb pdb:6BHI|rcsb pdb:6D07|rcsb pdb:6D08|rcsb pdb:6E83|rcsb pdb:6E86|rcsb pdb:5WFC|rcsb pdb:6F6D|rcsb pdb:6HTS|rcsb pdb:6IEU|rcsb pdb:6IIS|rcsb pdb:6IIT|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6LS6|rcsb pdb:6LSD|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MIL|rcsb pdb:6MIM|rcsb pdb:6MIN|rcsb pdb:6MIO|rcsb pdb:6MIQ|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6HKT|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2H|rcsb pdb:6V2K|rcsb pdb:6V3N|rcsb pdb:6V41|rcsb pdb:6V92|rcsb pdb:6VIL|rcsb pdb:6WAV|rcsb pdb:6WW4|rcsb pdb:6YIF|rcsb pdb:6YIH|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:6R92|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7KLR|rcsb pdb:7LYC|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|ensembl:ENSG00000197153(gene)|ensembl:ENSG00000197409(gene)|ensembl:ENSG00000273983(gene)|ensembl:ENSG00000274750(gene)|ensembl:ENSG00000275379(gene)|ensembl:ENSG00000275714(gene)|ensembl:ENSG00000277775(gene)|ensembl:ENSG00000278828(gene)|ensembl:ENSG00000286522(gene)|ensembl:ENSG00000287080(gene)|ensembl:ENST00000356476(transcript)|ensembl:ENST00000359303(transcript)|ensembl:ENST00000369163(transcript)|ensembl:ENST00000612966(transcript)|ensembl:ENST00000613854(transcript)|ensembl:ENST00000614378(transcript)|ensembl:ENST00000614911(transcript)|ensembl:ENST00000616365(transcript)|ensembl:ENST00000618052(transcript)|ensembl:ENST00000621411(transcript)|ensembl:ENST00000634733(transcript)|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-3247509|reactome:R-HSA-9710421|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060968"(obsolete regulation of gene silencing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|interpro:IPR009072(Histone-fold)|mint:P68431|rcsb pdb:1CS9|rcsb pdb:1CT6|rcsb pdb:1O9S|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|rcsb pdb:1Q3L|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|rcsb pdb:2B2T|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|rcsb pdb:2B2U|rcsb pdb:2B2V|rcsb pdb:2B2W|rcsb pdb:2C1J|rcsb pdb:2C1N|go:"GO:0016020"(membrane)|rcsb pdb:2CO0|rcsb pdb:2CV5|rcsb pdb:2FSA|rcsb pdb:2KWJ|rcsb pdb:2KWK|rcsb pdb:2L75|rcsb pdb:2LBM|rcsb pdb:2LGG|rcsb pdb:2M0O|reactome:R-HSA-983231|reactome:R-HSA-977225|rcsb pdb:2NDG|rcsb pdb:2OQ6|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2RI7|rcsb pdb:2RR4|rcsb pdb:2UXN|rcsb pdb:2V85|rcsb pdb:2V89|rcsb pdb:2VNF|rcsb pdb:2VPG|rcsb pdb:2X0L|rcsb pdb:3A1B|rcsb pdb:2NDF|rcsb pdb:3AFA|rcsb pdb:3AVR|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3B95|rcsb pdb:3FDT|rcsb pdb:3KMT|rcsb pdb:3KQI|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3MP1|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O37|rcsb pdb:3QJ6|rcsb pdb:3RIG|rcsb pdb:3RIY|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3U31|rcsb pdb:3U3D|rcsb pdb:3U4S|rcsb pdb:3U5N|rcsb pdb:3U5O|rcsb pdb:3AZK|rcsb pdb:3U5P|rcsb pdb:3UEE|rcsb pdb:3UEF|rcsb pdb:3UII|rcsb pdb:3UIK|rcsb pdb:3V43|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:3ZG6|rcsb pdb:3ZVY|rcsb pdb:4A0J|rcsb pdb:4A0N|rcsb pdb:4A7J|rcsb pdb:3UIG|rcsb pdb:4BD3|rcsb pdb:4C1Q|rcsb pdb:4F4U|rcsb pdb:4F56|rcsb pdb:4FWF|rcsb pdb:4HON|rcsb pdb:4I51|rcsb pdb:4L7X|rcsb pdb:4LK9|rcsb pdb:4LKA|rcsb pdb:4LLB|rcsb pdb:4LXL|rcsb pdb:4N4H|rcsb pdb:4QBQ|rcsb pdb:4QBR|refseq:NP_003520.1|refseq:NP_003521.2|refseq:NP_003522.1|refseq:NP_003523.1|refseq:NP_003524.1|refseq:NP_003525.1|refseq:NP_003526.1|refseq:NP_003527.1|refseq:NP_003528.1|refseq:NP_066298.1|dip:DIP-29371N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:ood0OohxZHuhsWZtO7U7GMc+LwM9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P62266 intact:EBI-6150681 intact:EBI-353072|ensembl:ENSP00000296674|ensembl:ENSP00000498621|uniprotkb:P39028|uniprotkb:Q6IB08 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rs23_human(display_long)|uniprotkb:RPS23(gene name)|psi-mi:RPS23(display_short)|uniprotkb:Small ribosomal subunit protein uS12(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000186468(gene)|ensembl:ENST00000296674(transcript)|ensembl:ENST00000651545(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0034063"(stress granule assembly)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:1990145"(maintenance of translational fidelity)|interpro:IPR005680(Ribosomal protein S23, eukaryotic/archaeal)|interpro:IPR006032(Ribosomal protein S12/S23)|rcsb pdb:5T2C|rcsb pdb:5VYC|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|mint:P62266|rcsb pdb:6G4W|rcsb pdb:4CXG|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:4CXH|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:4UG0|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|refseq:NP_001016.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:MWZPvSL/G45ocaxA5AXKCkDQxNU9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q13247 intact:EBI-6150681 intact:EBI-745230|uniprotkb:Q13244|uniprotkb:Q13245|uniprotkb:Q96J06|uniprotkb:Q9UJB8|uniprotkb:Q9Y3N7|uniprotkb:B7Z6J3|uniprotkb:E1P5W6|ensembl:ENSP00000244020 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:srsf6_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP55(gene name synonym)|uniprotkb:SRSF6(gene name)|psi-mi:SRSF6(display_short)|uniprotkb:SRP55(gene name synonym)|uniprotkb:SFRS6(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_006266.2|ensembl:ENSG00000124193(gene)|ensembl:ENST00000244020(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0032868"(response to insulin)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061041"(regulation of wound healing)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029541|interpro:IPR034511|interpro:IPR035979|mint:Q13247|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:vU4nobP3g/hsgnll0mQgjJcME2k9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q92522 intact:EBI-6150681 intact:EBI-876335|ensembl:ENSP00000329662 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h1x_human(display_long)|uniprotkb:H1-10(gene name)|psi-mi:H1-10(display_short)|uniprotkb:H1FX(gene name synonym)|uniprotkb:Histone H1x(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) ensembl:ENSG00000184897(gene)|ensembl:ENST00000333762(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045296"(cadherin binding)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q92522|refseq:NP_006017.1|dip:DIP-36358N|rcsb pdb:2LSO|rcsb pdb:6L9Z|rcsb pdb:7K60|rcsb pdb:7K63 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:T+NweCoHXj0rYsS6gJ4V42R9MpA9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P62807 intact:EBI-6150681 intact:EBI-354552|uniprotkb:Q4VB69|uniprotkb:P02278|uniprotkb:Q3B872|uniprotkb:Q93078|uniprotkb:Q93080|ensembl:ENSP00000321744|ensembl:ENSP00000348924|ensembl:ENSP00000366962|ensembl:ENSP00000380180|ensembl:ENSP00000445633|ensembl:ENSP00000483237|ensembl:ENSP00000489317 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h2b1c_human(display_long)|uniprotkb:HIST1H2BG(gene name synonym)|uniprotkb:HIST1H2BI(gene name synonym)|uniprotkb:Histone H2B.1 A(gene name synonym)|uniprotkb:Histone H2B.a(gene name synonym)|uniprotkb:Histone H2B.g(gene name synonym)|uniprotkb:Histone H2B.h(gene name synonym)|uniprotkb:Histone H2B.k(gene name synonym)|uniprotkb:Histone H2B.l(gene name synonym)|uniprotkb:H2BC10(gene name)|psi-mi:H2BC10(display_short)|uniprotkb:H2BC4(gene name)|psi-mi:H2BC4(display_short)|uniprotkb:H2BC6(gene name)|psi-mi:H2BC6(display_short)|uniprotkb:H2BC7(gene name)|psi-mi:H2BC7(display_short)|uniprotkb:H2BC8(gene name)|psi-mi:H2BC8(display_short)|uniprotkb:H2BFA(gene name synonym)|uniprotkb:H2BFG(gene name synonym)|uniprotkb:H2BFH(gene name synonym)|uniprotkb:H2BFK(gene name synonym)|uniprotkb:H2BFL(gene name synonym)|uniprotkb:HIST1H2BC(gene name synonym)|uniprotkb:HIST1H2BE(gene name synonym)|uniprotkb:HIST1H2BF(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_003509.1|refseq:NP_003513.1|refseq:NP_003514.2|refseq:NP_003516.1|refseq:NP_003517.2|refseq:NP_066407.1|rcsb pdb:7A08|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|rcsb pdb:6XJD|ensembl:ENSG00000180596(gene)|ensembl:ENSG00000273802(gene)|ensembl:ENSG00000274290(gene)|ensembl:ENSG00000277224(gene)|ensembl:ENSG00000278588(gene)|ensembl:ENST00000314332(transcript)|ensembl:ENST00000356530(transcript)|ensembl:ENST00000377733(transcript)|ensembl:ENST00000396984(transcript)|ensembl:ENST00000541790(transcript)|ensembl:ENST00000614097(transcript)|ensembl:ENST00000634910(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0042802"(identical protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P62807|rcsb pdb:5GT0|rcsb pdb:5KGF|rcsb pdb:6ACO|rcsb pdb:6C0W|rcsb pdb:6FML|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6X59|rcsb pdb:6X5A|dip:DIP-32890N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:00sapwbWn8dtUr7qoPsRPUlL35A9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q9BQG0 intact:EBI-6150681 intact:EBI-676973|intact:EBI-2559619|uniprotkb:Q86VM3|uniprotkb:Q9BW49|uniprotkb:Q9P0V5|uniprotkb:Q9UF99|ensembl:ENSP00000254718 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:mbb1a_human(display_long)|uniprotkb:MYBBP1A(gene name)|psi-mi:MYBBP1A(display_short)|uniprotkb:P160(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001099008.1|refseq:NP_055335.2|ensembl:ENST00000254718(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042254"(ribosome biogenesis)|ensembl:ENSG00000132382(gene)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR007015(DNA polymerase V)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9BQG0|reactome:R-HSA-5250924 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:ScabTPXvbX/5VRsnaRQXUIlANow9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P19338 intact:EBI-6150681 intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_005372.2|dip:DIP-89N|ensembl:ENSG00000115053(gene)|ensembl:ENST00000322723(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005938"(cell cortex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:O60814 intact:EBI-6150681 intact:EBI-4409738|uniprotkb:A8K7P7|uniprotkb:Q2VPI7|ensembl:ENSP00000349430 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h2b1k_human(display_long)|uniprotkb:H2BC12(gene name)|psi-mi:H2BC12(display_short)|uniprotkb:H2BFT(gene name synonym)|uniprotkb:HIRA-interacting protein 1(gene name synonym)|uniprotkb:HIRIP1(gene name synonym)|uniprotkb:HIST1H2BK(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_542160.1|refseq:NP_001299582.1|dip:DIP-48935N|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000197903(gene)|ensembl:ENST00000356950(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:O60814|rcsb pdb:2CV5|rcsb pdb:6KE9|rcsb pdb:6L9H|rcsb pdb:6LE9|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6V92|rcsb pdb:6Y5D|rcsb pdb:7BWD|rcsb pdb:7DBP|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:aBHcFUkMIdiiZov716H7kxmHzj09606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P31943 intact:EBI-6150681 intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168|ensembl:ENSP00000377082|ensembl:ENSP00000397797|ensembl:ENSP00000492076|ensembl:ENSP00000495786 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_005511.1|refseq:NP_001244222.1|ensembl:ENSG00000169045(gene)|ensembl:ENSG00000284254(gene)|ensembl:ENST00000356731(transcript)|ensembl:ENST00000393432(transcript)|ensembl:ENST00000442819(transcript)|ensembl:ENST00000638505(transcript)|ensembl:ENST00000643310(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q08170 intact:EBI-6150681 intact:EBI-722621|uniprotkb:Q5VXP1|uniprotkb:Q9BUA4|ensembl:ENSP00000362900|uniprotkb:Q9UEB5 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:srsf4_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP75(gene name synonym)|uniprotkb:SRP001LB(gene name synonym)|uniprotkb:SFRS4(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 4(gene name synonym)|uniprotkb:SRSF4(gene name)|psi-mi:SRSF4(display_short)|uniprotkb:SRP75(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_005617.2|ensembl:ENSG00000116350(gene)|ensembl:ENST00000373795(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032868"(response to insulin)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035585|interpro:IPR035979|mint:Q08170|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:LVIhOlsJ8rUYB68fWFDsovUGTeU9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P10809 intact:EBI-6150681 intact:EBI-352528|ensembl:ENSP00000340019|ensembl:ENSP00000373620|ensembl:ENSP00000396460|ensembl:ENSP00000402478|ensembl:ENSP00000412227|ensembl:ENSP00000412717|ensembl:ENSP00000414446|ensembl:ENSP00000503139|ensembl:ENSP00000503894|uniprotkb:Q38L19|uniprotkb:B2R5M6|uniprotkb:Q9UCR6|uniprotkb:B7Z712 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:ch60_human(display_long)|uniprotkb:HSPD1(gene name)|psi-mi:HSPD1(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:P60 lymphocyte protein(gene name synonym)|uniprotkb:HuCHA60(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_002147.2|refseq:NP_955472.1|ensembl:ENSG00000144381(gene)|ensembl:ENST00000345042(transcript)|ensembl:ENST00000388968(transcript)|ensembl:ENST00000418022(transcript)|ensembl:ENST00000426480(transcript)|ensembl:ENST00000428204(transcript)|ensembl:ENST00000439605(transcript)|ensembl:ENST00000452200(transcript)|ensembl:ENST00000677913(transcript)|ensembl:ENST00000678761(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051604"(protein maturation)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P10809|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|rcsb pdb:7AZP|reactome:R-HSA-1268020|reactome:R-HSA-8869496|dip:DIP-58N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:syB2vt66Cpr2mJROfbxoPevoiRE9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P36578 intact:EBI-6150681 intact:EBI-348313|ensembl:ENSP00000311430|uniprotkb:P39029|uniprotkb:Q4VBR0|uniprotkb:Q969Z9|uniprotkb:A8K502 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl4_human(display_long)|uniprotkb:RPL4(gene name)|psi-mi:RPL4(display_short)|uniprotkb:RPL1(gene name synonym)|uniprotkb:60S ribosomal protein L1(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) ensembl:ENSG00000174444(gene)|ensembl:ENST00000307961(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002136(Ribosomal protein L4/L1e)|interpro:IPR013000(Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site)|interpro:IPR025755|mint:P36578|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|interpro:IPR023574|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6OM0|refseq:NP_000959.2|dip:DIP-27559N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:34il/jyrW0Dqj0eA8GBFgUk05XU9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P68104 intact:EBI-6150681 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q99878 intact:EBI-6150681 intact:EBI-6147676|uniprotkb:Q5JXQ5|uniprotkb:A2RUU6|ensembl:ENSP00000328484 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h2a1j_human(display_long)|uniprotkb:H2AC14(gene name)|psi-mi:H2AC14(display_short)|uniprotkb:H2AFE(gene name synonym)|uniprotkb:HIST1H2AJ(gene name synonym)|uniprotkb:Histone H2A/e(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_066544.1|ensembl:ENSG00000276368(gene)|ensembl:ENST00000333151(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:tS29VG3PpglHaYbu0w5z7pGvYyI9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P0C0S8 intact:EBI-6150681 intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P15880 intact:EBI-6150681 intact:EBI-443446|ensembl:ENSP00000341885|uniprotkb:Q3MIB1|uniprotkb:B2R5G0|uniprotkb:D3DU82 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rs2_human(display_long)|uniprotkb:RPS2(gene name)|psi-mi:RPS2(display_short)|uniprotkb:RPS4(gene name synonym)|uniprotkb:40S ribosomal protein S4(gene name synonym)|uniprotkb:Protein LLRep3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|rcsb pdb:6OLG|rcsb pdb:6OLI|interpro:IPR018192|rcsb pdb:6OLZ|interpro:IPR020568|mint:P15880|rcsb pdb:4UG0|rcsb pdb:6OM0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6EK0|rcsb pdb:6G18|rcsb pdb:6XA1|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6G5H|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7JQB|rcsb pdb:7JQC|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-3214858|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8876725|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:7A09|ensembl:ENSG00000140988(gene)|ensembl:ENST00000343262(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045296"(cadherin binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR005711(Ribosomal protein S5, eukaryotic/archaeal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|refseq:NP_002943.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:JUr2Y3cGk00S8KaTVPymshfaHhc9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P06748 intact:EBI-6150681 intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930|ensembl:ENSP00000428755 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_002511.1|refseq:NP_954654.1|refseq:NP_001032827.1|dip:DIP-30932N|ensembl:ENSG00000181163(gene)|ensembl:ENST00000296930(transcript)|ensembl:ENST00000517671(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001652"(granular component)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006407"(rRNA export from nucleus)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019843"(rRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042255"(ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060699"(regulation of endoribonuclease activity)|go:"GO:0060735"(regulation of eIF2 alpha phosphorylation by dsRNA)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902629"(regulation of mRNA stability involved in cellular response to UV)|go:"GO:1902751"(positive regulation of cell cycle G2/M phase transition)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P11940 intact:EBI-6150681 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P62269 intact:EBI-6150681 intact:EBI-352451|ensembl:ENSP00000211372|ensembl:ENSP00000393241|ensembl:ENSP00000403175|ensembl:ENSP00000412583|ensembl:ENSP00000416110|uniprotkb:P25232|uniprotkb:Q6IPF8|uniprotkb:Q5SUJ3 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rs18_human(display_long)|uniprotkb:RPS18(gene name)|psi-mi:RPS18(display_short)|uniprotkb:D6S218E(gene name synonym)|uniprotkb:Ke-3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS13(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_072045.1|ensembl:ENSG00000096150(gene)|ensembl:ENSG00000223367(gene)|ensembl:ENSG00000226225(gene)|ensembl:ENSG00000231500(gene)|ensembl:ENSG00000235650(gene)|ensembl:ENST00000211372(transcript)|ensembl:ENST00000434122(transcript)|ensembl:ENST00000439602(transcript)|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENST00000454021(transcript)|ensembl:ENST00000457341(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001892(Ribosomal protein S13)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR018269|interpro:IPR027437|mint:P62269|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|dip:DIP-32892N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:yOHgKM/BuvgGdqp1OEVPeuiABg89606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P62888 intact:EBI-6150681 intact:EBI-353116|uniprotkb:P04645|uniprotkb:Q502Z6|ensembl:ENSP00000287038|ensembl:ENSP00000428085|uniprotkb:B2R591 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl30_human(display_long)|uniprotkb:RPL30(gene name)|psi-mi:RPL30(display_short)|uniprotkb:Large ribosomal subunit protein eL30(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) ensembl:ENSG00000156482(gene)|ensembl:ENST00000287038(transcript)|ensembl:ENST00000521291(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000231(Ribosomal protein L30e)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR022991|interpro:IPR029064|interpro:IPR039109|mint:P62888|rcsb pdb:3VI6|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000980.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:xR9LwYg6N7m9njT1pYumOPKZVu49606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P04908 intact:EBI-6150681 intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:4Qno1mMYZB6FdNoojrzulWLVq849606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q8N257 intact:EBI-6150681 intact:EBI-6150245|uniprotkb:Q5TA30|uniprotkb:Q3ZCP6|uniprotkb:A4FU05|ensembl:ENSP00000479284|ensembl:ENSP00000496342 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h2b3b_human(display_long)|uniprotkb:H2BU1(gene name)|psi-mi:H2BU1(display_short)|uniprotkb:H2B type 12(gene name synonym)|uniprotkb:H2B.U histone 1(gene name synonym)|uniprotkb:HIST3H2BB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_778225.1|ensembl:ENSG00000196890(gene)|ensembl:ENSG00000285449(gene)|ensembl:ENST00000620438(transcript)|ensembl:ENST00000647549(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q8N257|rcsb pdb:6BIZ|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:MnRK2NXd2p3rWO8GPfErAa273eY9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P18077 intact:EBI-6150681 intact:EBI-353383|uniprotkb:Q08ES9|uniprotkb:Q9BVN7|ensembl:ENSP00000393393|ensembl:ENSP00000495672 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl35a_human(display_long)|uniprotkb:RPL35A(gene name)|psi-mi:RPL35A(display_short)|uniprotkb:Cell growth-inhibiting gene 33 protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL33(gene name synonym)|uniprotkb:GIG33(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_000987.2|refseq:NP_001303240.1|ensembl:ENST00000647248(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001780(Ribosomal protein L35Ae)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR018266|interpro:IPR038661|mint:P18077|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|ensembl:ENSG00000182899(gene)|ensembl:ENST00000448864(transcript)|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:fnUlL17LsiOp3lSkKNsoYO74IQQ9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P62906 intact:EBI-6150681 intact:EBI-356860|uniprotkb:P52859|uniprotkb:P53025|uniprotkb:Q5TZT6|uniprotkb:Q8J013|uniprotkb:B2R801|ensembl:ENSP00000363018 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl10a_human(display_long)|uniprotkb:RPL10A(gene name)|psi-mi:RPL10A(display_short)|uniprotkb:NEDD6(gene name synonym)|uniprotkb:CSA-19(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 6(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_009035.3|ensembl:ENSG00000198755(gene)|ensembl:ENST00000322203(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002143(Ribosomal protein L1)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023673|interpro:IPR023674|interpro:IPR028364|mint:P62906|rcsb pdb:4UG0|rcsb pdb:4V6X|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LU8|rcsb pdb:6OLG|rcsb pdb:6QZP|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:wrXKX6vzZ3ovXP3yUoL1/r+NGiw9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q9HCC0 intact:EBI-6150681 intact:EBI-2211296|uniprotkb:A6NIY9|uniprotkb:Q96C27|uniprotkb:Q9Y4L7|ensembl:ENSP00000343657 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:mccb_human(display_long)|uniprotkb:MCCC2(gene name)|psi-mi:MCCC2(display_short)|uniprotkb:MCCB(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta"(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_071415.1|refseq:XP_005248624.1|ensembl:ENSG00000131844(gene)|ensembl:ENST00000340941(transcript)|go:"GO:0002169"(3-methylcrotonyl-CoA carboxylase complex, mitochondrial)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR029045|interpro:IPR034733|mint:Q9HCC0|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70895 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:5NkqDKqdX1wHsbqXW7v5+/Gld109606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q6NVV1 intact:EBI-6150681 intact:EBI-2880684 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:r13p3_human(display_long)|uniprotkb:RPL13AP3(gene name)|psi-mi:RPL13AP3(display_short)|uniprotkb:60S ribosomal protein L13a pseudogene 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR005822(Ribosomal protein L13)|interpro:IPR036899 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:XmYWkWYmWbCrPqmISrFtJ/k+cnI9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P40429 intact:EBI-6150681 intact:EBI-720205|uniprotkb:A8K505|ensembl:ENSP00000375730 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl13a_human(display_long)|uniprotkb:23 kDa highly basic protein(gene name synonym)|uniprotkb:RPL13A(gene name)|psi-mi:RPL13A(display_short)|uniprotkb:Large ribosomal subunit protein uL13(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_036555.1|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|rcsb pdb:6OLF|ensembl:ENSG00000142541(gene)|ensembl:ENST00000391857(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1901194"(negative regulation of formation of translation preinitiation complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005755(Ribosomal protein L13, eukaryotic/archaeal)|interpro:IPR005822(Ribosomal protein L13)|interpro:IPR023563|interpro:IPR036899|mint:P40429|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|refseq:NP_001257420.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:pcKDTEBZXxtm1MAH+4nv0p3PqFs9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q5QNW6 intact:EBI-6150681 intact:EBI-6147754|uniprotkb:B4DLA9|uniprotkb:A8K0U9|ensembl:ENSP00000358164 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h2b2f_human(display_long)|uniprotkb:H2BC18(gene name)|psi-mi:H2BC18(display_short)|uniprotkb:H2B-clustered histone 18(gene name synonym)|uniprotkb:HIST2H2BF(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001019770.1|refseq:NP_001154806.1|ensembl:ENSG00000203814(gene)|ensembl:ENST00000369167(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q5QNW6|rcsb pdb:6MUO|rcsb pdb:6MUP|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-5689880|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:Pr400UVIaD7O446lc9vZeStUKn09606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P05166 intact:EBI-6150681 intact:EBI-1371908|uniprotkb:Q16813|uniprotkb:Q96CX0|uniprotkb:B7Z2Z4|ensembl:ENSP00000251654 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:pccb_human(display_long)|uniprotkb:PCCB(gene name)|psi-mi:PCCB(display_short)|uniprotkb:"Propanoyl-CoA:carbon dioxide ligase subunit beta"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_000523.2|refseq:NP_001171485.1|dip:DIP-38244N|mint:P05166|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-71032|interpro:IPR034733|ensembl:ENSG00000114054(gene)|ensembl:ENST00000251654(transcript)|go:"GO:0004658"(propionyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0019626"(short-chain fatty acid catabolic process)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR029045 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:QyhO7MHvNRxNMg7ohwi1xS+VxQE9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 intact:EBI-6147672 intact:EBI-6150681 - psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:p0c7m2_human(display_short)|psi-mi:EBI-6147672(display_long) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) uniprotkb:P0C7M2(uniprot-removed-ac) - - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 - intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q16778 intact:EBI-6150681 intact:EBI-1056125|uniprotkb:A3KMC7|uniprotkb:Q4KMY1|uniprotkb:Q5QNX0|uniprotkb:Q9UE88|uniprotkb:A8K110|ensembl:ENSP00000358151 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h2b2e_human(display_long)|uniprotkb:H2BC21(gene name)|psi-mi:H2BC21(display_short)|uniprotkb:H2B-clustered histone 21(gene name synonym)|uniprotkb:H2BFQ(gene name synonym)|uniprotkb:HIST2H2BE(gene name synonym)|uniprotkb:Histone H2B-GL105(gene name synonym)|uniprotkb:Histone H2B.q(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_003519.1|ensembl:ENSG00000184678(gene)|ensembl:ENST00000369155(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q16778|rcsb pdb:4NFT|rcsb pdb:6A7U|rcsb pdb:6KBB|rcsb pdb:6M4D|rcsb pdb:6M4G|rcsb pdb:6M4H|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|rcsb pdb:7BXT|dip:DIP-39324N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:jh5U2ATjpAVt5DYOgr9YbcVdEzw9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q9BQE3 intact:EBI-6150681 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q96RQ3 intact:EBI-6150681 intact:EBI-2211703|uniprotkb:Q59ES4|uniprotkb:Q9H959|uniprotkb:Q9NS97|ensembl:ENSP00000265594 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:mcca_human(display_long)|uniprotkb:MCCC1(gene name)|psi-mi:MCCC1(display_short)|uniprotkb:MCCA(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase 1(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha"(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase biotin-containing subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_064551.3|refseq:NP_001280202.1|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR016185(PreATP-grasp-like fold)|mint:Q96RQ3|rcsb pdb:2EJM|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70895|ensembl:ENSG00000078070(gene)|ensembl:ENST00000265594(transcript)|go:"GO:0002169"(3-methylcrotonyl-CoA carboxylase complex, mitochondrial)|go:"GO:0004075"(biotin carboxylase activity)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0006768"(biotin metabolic process)|go:"GO:0009374"(biotin binding)|go:"GO:0016421"(CoA carboxylase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:obze7v7i2yTIIcJjd7laIriNFg89606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P26196 intact:EBI-6150681 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q8WWM7 intact:EBI-6150681 intact:EBI-948363|ensembl:ENSP00000338718|uniprotkb:O95135|uniprotkb:Q6NVJ8|uniprotkb:Q6PJW6|uniprotkb:Q8IU61|uniprotkb:Q8IU95|uniprotkb:Q8WWM3|uniprotkb:Q8WWM4|uniprotkb:Q8WWM5|uniprotkb:Q8WWM6|uniprotkb:Q99703|uniprotkb:B9EGM2|uniprotkb:E9PAR9|uniprotkb:A8K1R6|uniprotkb:Q63ZY4 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:atx2l_human(display_long)|uniprotkb:Ataxin-2 domain protein(gene name synonym)|uniprotkb:Ataxin-2-related protein(gene name synonym)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short)|uniprotkb:A2D(gene name synonym)|uniprotkb:A2LG(gene name synonym)|uniprotkb:A2LP(gene name synonym)|uniprotkb:A2RP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) ensembl:ENSG00000168488(gene)|ensembl:ENST00000336783(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045296"(cadherin binding)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR025852|mint:Q8WWM7|refseq:NP_009176.2|refseq:NP_663760.1|refseq:NP_680780.1|refseq:NP_680781.1|refseq:XP_005255123.1|refseq:NP_059867.3|refseq:NP_680782.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:t7lrS10IM/5pt+rrbqBRowZ6b+09606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P62244 intact:EBI-6150681 intact:EBI-347895|ensembl:ENSP00000318646|ensembl:ENSP00000457000|ensembl:ENSP00000458115|ensembl:ENSP00000458528|uniprotkb:P39027|uniprotkb:P39031|uniprotkb:Q3MHD9|uniprotkb:Q8C023|uniprotkb:Q9BV24 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rs15a_human(display_long)|uniprotkb:RPS15A(gene name)|psi-mi:RPS15A(display_short)|uniprotkb:Small ribosomal subunit protein uS8(gene name synonym)|uniprotkb:OK/SW-cl.82(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) ensembl:ENSG00000134419(gene)|ensembl:ENST00000322989(transcript)|ensembl:ENST00000563390(transcript)|ensembl:ENST00000565420(transcript)|ensembl:ENST00000572008(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045787"(positive regulation of cell cycle)|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|go:"GO:0070062"(extracellular exosome)|rcsb pdb:6G4W|interpro:IPR000630(Ribosomal protein S8)|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|interpro:IPR035987|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|mint:P62244|rcsb pdb:4UG0|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:4V6X|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-72695|reactome:R-HSA-975957|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZM7|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|refseq:NP_001010.2|refseq:NP_001025180.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:Qdnhk7yvoFFYcRq5kEi7GQILaxs9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P61513 intact:EBI-6150681 intact:EBI-356793|uniprotkb:P12751|intact:EBI-1051378|uniprotkb:Q6FGF5|ensembl:ENSP00000418082 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl37a_human(display_long)|uniprotkb:RPL37A(gene name)|psi-mi:RPL37A(display_short)|uniprotkb:Large ribosomal subunit protein eL43(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_000989.1|ensembl:ENSG00000197756(gene)|ensembl:ENST00000491306(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002674(Ribosomal protein L37ae)|interpro:IPR011331(Ribosomal protein L37ae/L37e, core)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:P61513|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:0kwO2cVd99FGF2+5FyWo94C83049606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P04406 intact:EBI-6150681 intact:EBI-354056|uniprotkb:P00354|uniprotkb:Q53X65|uniprotkb:E7EUT4|ensembl:ENSP00000229239|ensembl:ENSP00000380068|ensembl:ENSP00000380070 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:g3p_human(display_long)|uniprotkb:GAPDH(gene name)|psi-mi:GAPDH(display_short)|uniprotkb:OK/SW-cl.12(orf name)|uniprotkb:CDABP0047(orf name)|uniprotkb:GAPD(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_002037.2|refseq:NP_001243728.1|refseq:NP_001276674.1|refseq:NP_001276675.1|dip:DIP-32521N|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P04406|rcsb pdb:1U8F|rcsb pdb:1ZNQ|rcsb pdb:2FEH|rcsb pdb:3GPD|rcsb pdb:4WNC|rcsb pdb:4WNI|rcsb pdb:6ADE|rcsb pdb:6M61|rcsb pdb:6YND|rcsb pdb:6YNE|rcsb pdb:6YNF|rcsb pdb:6YNH|reactome:R-HSA-70171|reactome:R-HSA-70263|rcsb pdb:6IQ6|ensembl:ENSG00000111640(gene)|ensembl:ENST00000229239(transcript)|ensembl:ENST00000396859(transcript)|ensembl:ENST00000396861(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0031640"(killing of cells of another organism) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:9YENN/dfKl/d0tJtfFyQp2o8eAc9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q16695 intact:EBI-6150681 intact:EBI-358900|uniprotkb:Q6FGU4|uniprotkb:B2R5K3|ensembl:ENSP00000355657|ensembl:ENSP00000494070 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h31t_human(display_long)|uniprotkb:H3-4(gene name)|psi-mi:H3-4(display_short)|uniprotkb:H3/g(gene name synonym)|uniprotkb:H3FT(gene name synonym)|uniprotkb:HIST3H3(gene name synonym)|uniprotkb:Histone H3.4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_003484.1|ensembl:ENSG00000168148(gene)|ensembl:ENSG00000285435(gene)|ensembl:ENST00000366696(transcript)|ensembl:ENST00000644869(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q16695|rcsb pdb:2V1D|rcsb pdb:2YBP|rcsb pdb:2YBS|rcsb pdb:3A6N|rcsb pdb:3T6R|rcsb pdb:4V2V|rcsb pdb:4V2W|rcsb pdb:6OIE|rcsb pdb:6WAT|rcsb pdb:6WAU|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-201722|reactome:R-HSA-2299718|reactome:R-HSA-2559586|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-9670095|dip:DIP-922N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:izXHIcNCPCDQ7yevMtqWxTRt1bA9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q9Y3U8 intact:EBI-6150681 intact:EBI-1057689|uniprotkb:Q6FIG1|uniprotkb:Q9UQF6|uniprotkb:B2R4Y1|uniprotkb:D6W634|ensembl:ENSP00000252543|ensembl:ENSP00000378081|ensembl:ENSP00000462609|ensembl:ENSP00000464342 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl36_human(display_long)|uniprotkb:RPL36(gene name)|psi-mi:RPL36(display_short)|uniprotkb:Large ribosomal subunit protein eL36(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_056229.2|refseq:NP_378669.1|reactome:R-HSA-975957|mint:Q9Y3U8|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|interpro:IPR038097|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|rcsb pdb:6Y6X|ensembl:ENSG00000130255(gene)|ensembl:ENST00000347512(transcript)|ensembl:ENST00000394580(transcript)|ensembl:ENST00000577222(transcript)|ensembl:ENST00000579649(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR000509(Ribosomal protein L36e) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:lRlRMF2jV/UHr4SX95SSCFIEV+s9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q9UNX3 intact:EBI-6150681 intact:EBI-2949703|ensembl:ENSP00000265100|ensembl:ENSP00000428177|ensembl:ENSP00000428223|ensembl:ENSP00000430147|uniprotkb:B3KY82|uniprotkb:D3DQM0 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl26l_human(display_long)|uniprotkb:RPL26L1(gene name)|psi-mi:RPL26L1(display_short)|uniprotkb:RPL26P1(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL24-like 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) ensembl:ENSG00000037241(gene)|ensembl:ENST00000265100(transcript)|ensembl:ENST00000519239(transcript)|ensembl:ENST00000519974(transcript)|ensembl:ENST00000521476(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005756(Ribosomal protein L26, eukaryotic/archaeal)|interpro:IPR005824(KOW)|interpro:IPR005825(Ribosomal protein L24/L26, conserved site)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041988|mint:Q9UNX3|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-2408557|refseq:NP_057177.1|refseq:XP_011532867.1|refseq:NP_001304909.1|refseq:NP_001304910.1|refseq:NP_001304911.1|refseq:XP_016865008.1|refseq:XP_016865009.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:dny/DWK4MvWD3FUJvW5+KGI3iJI9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P83731 intact:EBI-6150681 intact:EBI-353146|ensembl:ENSP00000377640|uniprotkb:P38663|uniprotkb:Q6IBS3|uniprotkb:B2R4Y3 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl24_human(display_long)|uniprotkb:RPL24(gene name)|psi-mi:RPL24(display_short)|uniprotkb:60S ribosomal protein L30(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL24(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) go:"GO:0016020"(membrane)|go:"GO:0021554"(optic nerve development)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR000988(Ribosomal protein L24e)|interpro:IPR011017(TRASH)|interpro:IPR023442|interpro:IPR038630|mint:P83731|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZMI|rcsb pdb:6ZME|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000114391(gene)|ensembl:ENST00000394077(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0010458"(exit from mitosis)|refseq:NP_000977.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:+Ah+YGgcjqOsk5ZS1HZUMQA/Of89606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P84098 intact:EBI-6150681 intact:EBI-916524|uniprotkb:P14118|uniprotkb:P22908|uniprotkb:Q502Y6|uniprotkb:Q7Z6E4|uniprotkb:B2R4K2|ensembl:ENSP00000225430 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl19_human(display_long)|uniprotkb:RPL19(gene name)|psi-mi:RPL19(display_short)|uniprotkb:Large ribosomal subunit protein eL19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_000972.1|ensembl:ENSG00000108298(gene)|ensembl:ENST00000225430(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0097421"(liver regeneration)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR000196(Ribosomal protein L19/L19e)|interpro:IPR015972(Ribosomal protein L19/L19e, domain 1)|interpro:IPR023638|interpro:IPR033935|interpro:IPR035970|interpro:IPR039547|mint:P84098|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:sYEwdB8ySbxh3iL0uqlfRRVFiWw9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P25705 intact:EBI-6150681 intact:EBI-351437|uniprotkb:Q53XX6|uniprotkb:Q8IXV2|uniprotkb:Q96FB4|uniprotkb:Q96HW2|uniprotkb:Q96IR6|uniprotkb:Q9BTV8|intact:EBI-11032691|uniprotkb:A8K092|uniprotkb:B4DY56|uniprotkb:K7ENP3|ensembl:ENSP00000282050|ensembl:ENSP00000381736 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:atpa_human(display_long)|uniprotkb:ATP5F1A(gene name)|psi-mi:ATP5F1A(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5A1(gene name synonym)|uniprotkb:ATP5AL2(gene name synonym)|uniprotkb:ATPM(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001244263.1|refseq:NP_001001937.1|refseq:NP_004037.1|refseq:NP_001001935.1|refseq:NP_001244264.1|dip:DIP-32871N|ensembl:ENSG00000152234(gene)|ensembl:ENST00000282050(transcript)|ensembl:ENST00000398752(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:P25705|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-8949613 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:Sy/Ii5ea+ilCKGBnIEMn133Vogc9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P16989 intact:EBI-6150681 intact:EBI-358193|uniprotkb:Q14121|uniprotkb:Q969N6|uniprotkb:Q96B76|uniprotkb:B2RBW6|intact:EBI-2560381|ensembl:ENSP00000228251 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:ybox3_human(display_long)|uniprotkb:YBX3(gene name)|psi-mi:YBX3(display_short)|uniprotkb:CSDA(gene name synonym)|uniprotkb:Cold shock domain-containing protein A(gene name synonym)|uniprotkb:DBPA(gene name synonym)|uniprotkb:DNA-binding protein A(gene name synonym)|uniprotkb:Single-strand DNA-binding protein NF-GMB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) go:"GO:0046622"(positive regulation of organ growth)|refseq:NP_001138898.1|refseq:NP_003642.3|dip:DIP-42489N|ensembl:ENSG00000060138(gene)|ensembl:ENST00000228251(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008584"(male gonad development)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031267"(small GTPase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:1902219"(negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1905538"(polysome binding)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P16989 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:cWuhmwOBWe5HdgPG1gyN7KzN4Rs9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P83881 intact:EBI-6150681 intact:EBI-1054835|uniprotkb:P09896|uniprotkb:P10661|uniprotkb:Q5J9I6|uniprotkb:Q08ES5|ensembl:ENSP00000446503 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl36a_human(display_long)|uniprotkb:60S ribosomal protein L44(gene name synonym)|uniprotkb:Cell migration-inducing gene 6 protein(gene name synonym)|uniprotkb:RPL36A(gene name)|psi-mi:RPL36A(display_short)|uniprotkb:MIG6(orf name)|uniprotkb:RPL44(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 15 protein(gene name synonym)|uniprotkb:GIG15(orf name)|uniprotkb:Large ribosomal subunit protein eL42(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_066357.2|ensembl:ENSG00000241343(gene)|ensembl:ENST00000553110(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR000552(Ribosomal protein L44e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:P83881|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:OrRyOEVJZbSdttK93KL/DS5YxJ89606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P60866 intact:EBI-6150681 intact:EBI-353105|uniprotkb:P17075|uniprotkb:Q5M8S9|uniprotkb:B2R4F4|uniprotkb:B4DW28|ensembl:ENSP00000009589|ensembl:ENSP00000427788|ensembl:ENSP00000503327|ensembl:ENSP00000504123|ensembl:ENSP00000504154|ensembl:ENSP00000504670 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rs20_human(display_long)|uniprotkb:RPS20(gene name)|psi-mi:RPS20(display_short)|uniprotkb:Small ribosomal subunit protein uS10(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001014.1|refseq:NP_001139699.1|dip:DIP-31245N|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|ensembl:ENSG00000008988(gene)|ensembl:ENST00000009589(transcript)|ensembl:ENST00000521262(transcript)|ensembl:ENST00000676461(transcript)|ensembl:ENST00000676918(transcript)|ensembl:ENST00000678039(transcript)|ensembl:ENST00000678683(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR001848(Ribosomal protein S10)|interpro:IPR005729(Ribosomal protein S10, eukaryotic/archaeal)|interpro:IPR018268|interpro:IPR027486|interpro:IPR036838|mint:P60866|rcsb pdb:4UG0|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:6xNxX+eP59AOm0KraCysRHUqMFw9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q9HAV7 intact:EBI-6150681 intact:EBI-1043499|uniprotkb:Q549M6|uniprotkb:B2R783|ensembl:ENSP00000264954 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:grpe1_human(display_long)|uniprotkb:Mt-GrpE#1(gene name synonym)|uniprotkb:HMGE(gene name synonym)|uniprotkb:GRPEL1(gene name)|psi-mi:GRPEL1(display_short)|uniprotkb:GREPEL1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) ensembl:ENSG00000109519(gene)|ensembl:ENST00000264954(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR000740(GrpE nucleotide exchange factor)|interpro:IPR009012(GrpE nucleotide exchange factor, head)|interpro:IPR013805(GrpE nucleotide exchange factor, coiled-coil)|mint:Q9HAV7|reactome:R-HSA-1268020|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_079472.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:OWuX4gnZBzxgv0arSEKY9KyZZ+o9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:A5A3E0 intact:EBI-6150681 intact:EBI-6150673|uniprotkb:A6NC34|ensembl:ENSP00000386786 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:potef_human(display_long)|uniprotkb:POTEF(gene name)|psi-mi:POTEF(display_short)|uniprotkb:A26C1B(gene name synonym)|uniprotkb:ANKRD26-like family C member 1B(gene name synonym)|uniprotkb:Chimeric POTE-actin protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001093241.1|ensembl:ENSG00000196604(gene)|ensembl:ENST00000409914(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005615"(extracellular space)|go:"GO:0005938"(cell cortex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR002110(Ankyrin)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020683|interpro:IPR020902|interpro:IPR036770|interpro:IPR039497|interpro:IPR043129 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:alL+OQ/juWHafyF1GwIiLOPZZso9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P62861 intact:EBI-6150681 intact:EBI-358093|uniprotkb:Q05472|uniprotkb:Q95261|uniprotkb:Q9H5V4|ensembl:ENSP00000431822|ensembl:ENSP00000434440|ensembl:ENSP00000435370 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rs30_human(display_long)|uniprotkb:FAU(gene name)|psi-mi:FAU(display_short)|uniprotkb:Small ribosomal subunit protein eS30(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) ensembl:ENSG00000149806(gene)|ensembl:ENST00000527548(transcript)|ensembl:ENST00000529639(transcript)|ensembl:ENST00000531743(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR006846(Ribosomal protein S30)|mint:P62861|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:mfW+tko85h9ZOK7wNXUsYiYY3Hc9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P06899 intact:EBI-6150681 intact:EBI-6150252|uniprotkb:B2R4J4|uniprotkb:O60816|ensembl:ENSP00000342886|ensembl:ENSP00000476136 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h2b1j_human(display_long)|uniprotkb:H2BC11(gene name)|psi-mi:H2BC11(display_short)|uniprotkb:H2BFR(gene name synonym)|uniprotkb:HIST1H2BJ(gene name synonym)|uniprotkb:Histone H2B.1(gene name synonym)|uniprotkb:Histone H2B.r(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_066402.2|dip:DIP-421N|ensembl:ENSG00000124635(gene)|ensembl:ENST00000339812(transcript)|ensembl:ENST00000607124(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P06899|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WAA|rcsb pdb:3WTP|rcsb pdb:4CAY|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5FUG|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5VEY|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6YOV|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7K5X|rcsb pdb:3WA9|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:74GQlSjGG1Ez6Uog74VXPLryKBc9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q71DI3 intact:EBI-6150681 intact:EBI-750650|uniprotkb:A2BDF6|uniprotkb:A6NFS4|uniprotkb:Q6B053|ensembl:ENSP00000333277|ensembl:ENSP00000358154|ensembl:ENSP00000385479 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h32_human(display_long)|uniprotkb:H3C13(gene name)|psi-mi:H3C13(display_short)|uniprotkb:H3C14(gene name)|psi-mi:H3C14(display_short)|uniprotkb:H3C15(gene name)|psi-mi:H3C15(display_short)|uniprotkb:H3-clustered histone 13(gene name synonym)|uniprotkb:H3-clustered histone 14(gene name synonym)|uniprotkb:H3-clustered histone 15(gene name synonym)|uniprotkb:H3F2(gene name synonym)|uniprotkb:H3FM(gene name synonym)|uniprotkb:HIST2H3A(gene name synonym)|uniprotkb:HIST2H3C(gene name synonym)|uniprotkb:HIST2H3D(gene name synonym)|uniprotkb:Histone H3/m(gene name synonym)|uniprotkb:Histone H3/o(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001005464.1|refseq:NP_001116847.1|refseq:NP_066403.2|dip:DIP-48606N|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|rcsb pdb:7BU9|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214858|reactome:R-HSA-3247509|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-983231|rcsb pdb:7JZV|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|ensembl:ENSG00000183598(gene)|ensembl:ENSG00000203811(gene)|ensembl:ENSG00000203852(gene)|ensembl:ENST00000331491(transcript)|ensembl:ENST00000369158(transcript)|ensembl:ENST00000403683(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q71DI3|rcsb pdb:2IIJ|rcsb pdb:2X4W|rcsb pdb:2X4X|rcsb pdb:2X4Y|rcsb pdb:3AV1|rcsb pdb:3DB3|rcsb pdb:3MO8|rcsb pdb:3QO2|rcsb pdb:3R93|rcsb pdb:4MZF|rcsb pdb:4MZG|rcsb pdb:4MZH|rcsb pdb:4OUC|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B40|rcsb pdb:5BO0|rcsb pdb:5CIU|rcsb pdb:5VAC|rcsb pdb:6ACE|rcsb pdb:6FML|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6Y5E|rcsb pdb:7BQZ - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P50914 intact:EBI-6150681 intact:EBI-356746|uniprotkb:Q45RF0|uniprotkb:Q53G20|uniprotkb:Q8TBD5|uniprotkb:Q8WUT0|uniprotkb:Q92579|uniprotkb:Q96GR0|uniprotkb:Q9BSB8|uniprotkb:Q9BW65|uniprotkb:Q9BYF6|ensembl:ENSP00000345156|ensembl:ENSP00000379506 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl14_human(display_long)|uniprotkb:RPL14(gene name)|psi-mi:RPL14(display_short)|uniprotkb:CAG-ISL 7(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001030168.1|refseq:NP_003964.3|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002784(Ribosomal protein L14)|interpro:IPR008991(Translation protein SH3-like)|ensembl:ENSG00000188846(gene)|ensembl:ENST00000338970(transcript)|ensembl:ENST00000396203(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041985|mint:P50914|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|interpro:IPR039660|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y2L - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:AjaguD5hgHtcBbJq5QfuG6XdTcE9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P32969 intact:EBI-6150681 intact:EBI-358122|ensembl:ENSP00000346022|ensembl:ENSP00000400467|ensembl:ENSP00000494697 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl9_human(display_long)|uniprotkb:RPL9(gene name)|psi-mi:RPL9(display_short)|uniprotkb:RPL9P7(gene name)|psi-mi:RPL9P7(display_short)|uniprotkb:RPL9P8(gene name)|psi-mi:RPL9P8(display_short)|uniprotkb:RPL9P9(gene name)|psi-mi:RPL9P9(display_short)|uniprotkb:Large ribosomal subunit protein uL6(gene name synonym)|uniprotkb:OK/SW-cl.103(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_000652.2|refseq:NP_001020092.1|ensembl:ENSG00000163682(gene)|ensembl:ENST00000295955(transcript)|ensembl:ENST00000449470(transcript)|ensembl:ENST00000645496(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR000702(Ribosomal protein L6)|interpro:IPR002359(Ribosomal protein L6, conserved site-2)|interpro:IPR020040|interpro:IPR036789|mint:P32969|rcsb pdb:2CQL|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:v0thFydYo0aEqBblJoqQX8b7JCA9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P52597 intact:EBI-6150681 intact:EBI-352986|ensembl:ENSP00000338477|ensembl:ENSP00000349573|ensembl:ENSP00000400433|ensembl:ENSP00000438061|ensembl:ENSP00000507787|ensembl:ENSP00000348345|uniprotkb:Q5T0N2|uniprotkb:Q96AU2|uniprotkb:B3KM84 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:hnrpf_human(display_long)|uniprotkb:HNRNPF(gene name)|psi-mi:HNRNPF(display_short)|uniprotkb:HNRPF(gene name synonym)|uniprotkb:Nucleolin-like protein mcs94-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P52597|rcsb pdb:2HGL|rcsb pdb:2HGM|rcsb pdb:2HGN|rcsb pdb:2KFY|rcsb pdb:2KG0|rcsb pdb:2KG1|rcsb pdb:3TFY|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensembl:ENSG00000169813(gene)|ensembl:ENST00000337970(transcript)|ensembl:ENST00000356053(transcript)|ensembl:ENST00000357065(transcript)|ensembl:ENST00000443950(transcript)|ensembl:ENST00000544000(transcript)|ensembl:ENST00000682386(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001091674.1|refseq:NP_001091675.1|refseq:NP_001091676.1|refseq:NP_001091677.1|refseq:NP_001091678.1|refseq:NP_004957.1|dip:DIP-33145N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:pblzpldZOa5vlZ+zGQY9qyWCxaw9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P20671 intact:EBI-6150681 intact:EBI-4407441|uniprotkb:A0PK91|uniprotkb:P57754|uniprotkb:Q6FGY6|ensembl:ENSP00000341094 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h2a1d_human(display_long)|uniprotkb:H2AC7(gene name)|psi-mi:H2AC7(display_short)|uniprotkb:H2AFG(gene name synonym)|uniprotkb:HIST1H2AD(gene name synonym)|uniprotkb:Histone H2A.3(gene name synonym)|uniprotkb:Histone H2A/g(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_066409.1|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000196866(gene)|ensembl:ENST00000341023(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:5GT3|rcsb pdb:6KBB|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:Geraq+dGw3pvAAhgzzXQnYxDOOw9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q99623 intact:EBI-6150681 intact:EBI-358348|uniprotkb:Q2YDA4|uniprotkb:Q7KYU3|uniprotkb:Q92978|ensembl:ENSP00000441875|uniprotkb:B4DP75 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:phb2_human(display_long)|uniprotkb:BAP(gene name synonym)|uniprotkb:REA(gene name synonym)|uniprotkb:PHB2(gene name)|psi-mi:PHB2(display_short)|uniprotkb:D-prohibitin(gene name synonym)|uniprotkb:B-cell receptor-associated protein BAP37(gene name synonym)|uniprotkb:Repressor of estrogen receptor activity(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001138303.1|ensembl:ENSG00000215021(gene)|ensembl:ENST00000535923(transcript)|go:"GO:0000423"(mitophagy)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016477"(cell migration)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030424"(axon)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033218"(amide binding)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071944"(cell periphery)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1900208"(regulation of cardiolipin metabolic process)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904959"(regulation of cytochrome-c oxidase activity)|go:"GO:1990051"(activation of protein kinase C activity)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:Q99623|rcsb pdb:6IQE|reactome:R-HSA-8949664|refseq:NP_001254629.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:h4pib54mBeQgOKCe/hib58LM26w9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P62280 intact:EBI-6150681 intact:EBI-1047710|uniprotkb:B2R4F5|uniprotkb:P04643|uniprotkb:Q498Y6|uniprotkb:Q6IRY0|ensembl:ENSP00000270625 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rs11_human(display_long)|uniprotkb:RPS11(gene name)|psi-mi:RPS11(display_short)|uniprotkb:Small ribosomal subunit protein uS17(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001006.1|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000266(Ribosomal protein S17)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019979|interpro:IPR028333|interpro:IPR032440|mint:P62280|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|go:"GO:0005840"(ribosome)|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|ensembl:ENSG00000142534(gene)|ensembl:ENST00000270625(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6OM0|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:0fqJjtWAuz31VTKt2mbteRoi8vA9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q99880 intact:EBI-6150681 intact:EBI-1237119|uniprotkb:Q52LW9|uniprotkb:B2R5A3|ensembl:ENSP00000366618 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h2b1l_human(display_long)|uniprotkb:H2BC13(gene name)|psi-mi:H2BC13(display_short)|uniprotkb:H2BFC(gene name synonym)|uniprotkb:HIST1H2BL(gene name synonym)|uniprotkb:Histone H2B.c(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_003510.1|dip:DIP-38154N|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|ensembl:ENSG00000185130(gene)|ensembl:ENST00000377401(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|interpro:IPR009072(Histone-fold)|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5250924|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:vVD3xoHavMKCopzEez7zarZBKFc9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P46783 intact:EBI-6150681 intact:EBI-354442|uniprotkb:Q5TZC0|uniprotkb:B2R4E3|ensembl:ENSP00000481646|ensembl:ENSP00000494190|ensembl:ENSP00000494440|ensembl:ENSP00000497917 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rs10_human(display_long)|uniprotkb:RPS10(gene name)|psi-mi:RPS10(display_short)|uniprotkb:Small ribosomal subunit protein eS10(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001005.1|refseq:NP_001190174.1|refseq:NP_001191020.1|ensembl:ENSG00000124614(gene)|ensembl:ENST00000464218(transcript)|ensembl:ENST00000467531(transcript)|ensembl:ENST00000621356(transcript)|ensembl:ENST00000648437(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR005326(Plectin/S10, N-terminal)|rcsb pdb:6G51|interpro:IPR036388|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|interpro:IPR037447|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|mint:P46783|rcsb pdb:4UG0|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:4V6X|rcsb pdb:6ZUO|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|rcsb pdb:5T2C|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:GWUAJh7s0w/ar/SOpx0hiIJOr2c9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P09651 intact:EBI-6150681 intact:EBI-352662|uniprotkb:Q3MIB7|uniprotkb:Q6PJZ7|ensembl:ENSP00000341826|ensembl:ENSP00000503610|uniprotkb:A8K4Z8|intact:EBI-2556572 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:roa1_human(display_long)|uniprotkb:HNRNPA1(gene name)|psi-mi:HNRNPA1(display_short)|uniprotkb:HNRPA1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:Single-strand RNA-binding protein(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_002127.1|refseq:NP_112420.1|ensembl:ENSG00000135486(gene)|ensembl:ENST00000340913(transcript)|ensembl:ENST00000677210(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|rcsb pdb:2LYV|rcsb pdb:2UP1|rcsb pdb:4YOE|rcsb pdb:5MPG|rcsb pdb:5MPL|rcsb pdb:5ZGD|rcsb pdb:5ZGL|rcsb pdb:6BXX|rcsb pdb:6DCL|rcsb pdb:6J60|rcsb pdb:7BX7|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035198"(miRNA binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051170"(import into nucleus)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR034845|interpro:IPR035979|mint:P09651|rcsb pdb:1HA1|rcsb pdb:1L3K|rcsb pdb:1PGZ|rcsb pdb:1PO6|rcsb pdb:1U1K|rcsb pdb:1U1L|rcsb pdb:1U1M|rcsb pdb:1U1N|rcsb pdb:1U1O|rcsb pdb:1U1P|rcsb pdb:1U1Q|rcsb pdb:1U1R|rcsb pdb:1UP1|rcsb pdb:2H4M|refseq:XP_005268883.1|dip:DIP-29338N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:ECXjsLRVtNc/aOw90tEFxowHc6c9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P62736 intact:EBI-6150681 intact:EBI-698810|uniprotkb:P03996|uniprotkb:P04108|uniprotkb:Q6FI19|uniprotkb:B2R8A4|ensembl:ENSP00000224784 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:acta_human(display_long)|uniprotkb:Alpha-actin-2(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 46 protein(gene name synonym)|uniprotkb:ACTA2(gene name)|psi-mi:ACTA2(display_short)|uniprotkb:ACTSA(gene name synonym)|uniprotkb:ACTVS(gene name synonym)|uniprotkb:GIG46(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001135417.1|refseq:NP_001604.1|refseq:NP_001307784.1|ensembl:ENSG00000107796(gene)|ensembl:ENST00000224784(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014829"(vascular associated smooth muscle contraction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072144"(glomerular mesangial cell development)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P62736|reactome:R-HSA-445355|reactome:R-HSA-9013695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:mRZGUdL/jBuj6nVHtxoasZuA7yA9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P18621 intact:EBI-6150681 intact:EBI-726937|uniprotkb:Q6NZ54|uniprotkb:Q7M4M5|uniprotkb:Q3KQW2|uniprotkb:B2R4H3|uniprotkb:B4E3C2|uniprotkb:B5ME31|uniprotkb:J3QL51|ensembl:ENSP00000462023|ensembl:ENSP00000462385|ensembl:ENSP00000463842|ensembl:ENSP00000480555|ensembl:ENSP00000482577 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl17_human(display_long)|uniprotkb:60S ribosomal protein L23(gene name synonym)|uniprotkb:PD-1(gene name synonym)|uniprotkb:RPL17(gene name)|psi-mi:RPL17(display_short)|uniprotkb:Large ribosomal subunit protein uL22(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_000976.1|refseq:NP_001030178.1|refseq:NP_001186269.1|refseq:NP_001186270.1|refseq:NP_001186271.1|refseq:NP_001186272.1|refseq:NP_001186273.1|refseq:NP_001186274.1|ensembl:ENSG00000265681(gene)|ensembl:ENST00000579248(transcript)|ensembl:ENST00000579408(transcript)|ensembl:ENST00000580261(transcript)|ensembl:ENST00000618613(transcript)|ensembl:ENST00000618619(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001063(Ribosomal protein L22/L17)|interpro:IPR005721(Ribosomal protein L22/L17, eukaryotic/archaeal)|interpro:IPR018260|interpro:IPR036394|mint:P18621|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:/i0W3WoeFakz+8R/YMYf2JQZytI9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P25398 intact:EBI-6150681 intact:EBI-354542|uniprotkb:Q76M58|ensembl:ENSP00000230050 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rs12_human(display_long)|uniprotkb:RPS12(gene name)|psi-mi:RPS12(display_short)|uniprotkb:Small ribosomal subunit protein eS12(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001007.2|ensembl:ENSG00000112306(gene)|ensembl:ENST00000230050(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR000530(Ribosomal protein S12e)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR029064|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72702|reactome:R-HSA-72695|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:80AIouzSdCvnLUSA7qsMp6naZ3g9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P46778 intact:EBI-6150681 intact:EBI-350634|uniprotkb:Q16699|ensembl:ENSP00000346027|ensembl:ENSP00000351021|ensembl:ENSP00000370569|ensembl:ENSP00000370574 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl21_human(display_long)|uniprotkb:RPL21(gene name)|psi-mi:RPL21(display_short)|uniprotkb:Large ribosomal subunit protein eL21(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) rcsb pdb:6LU8|refseq:NP_000973.2|ensembl:ENSG00000122026(gene)|ensembl:ENST00000272274(transcript)|ensembl:ENST00000311549(transcript)|ensembl:ENST00000319826(transcript)|ensembl:ENST00000326092(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001147(Ribosomal protein L21e)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018259|interpro:IPR036948|mint:P46778|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6OLE|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:UCth+WL9Oj1Y9I5m4i/9X0a5WHk9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P05388 intact:EBI-6150681 intact:EBI-354101|uniprotkb:Q9BVK4|intact:EBI-8012155|intact:MINT-8395053|uniprotkb:Q3B7A4|ensembl:ENSP00000339027|ensembl:ENSP00000376299|ensembl:ENSP00000449328 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rla0_human(display_long)|uniprotkb:RPLP0(gene name)|psi-mi:RPLP0(display_short)|uniprotkb:60S ribosomal protein L10E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL10(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_000993.1|refseq:NP_444505.1|ensembl:ENSG00000089157(gene)|ensembl:ENST00000228306(transcript)|ensembl:ENST00000392514(transcript)|ensembl:ENST00000551150(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0098794"(postsynapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR030670|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:P05388|rcsb pdb:4V6W|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8950505|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:xv3QHqnXxvCd3BOIeHVkqEnSNNk9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q02878 intact:EBI-6150681 intact:EBI-359655|uniprotkb:Q2M3Q3|uniprotkb:Q8WW97|ensembl:ENSP00000202773|ensembl:ENSP00000403172 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl6_human(display_long)|uniprotkb:RPL6(gene name)|psi-mi:RPL6(display_short)|uniprotkb:TXREB1(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 107(gene name synonym)|uniprotkb:Neoplasm-related protein C140(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_000961.2|refseq:NP_001019833.1|ensembl:ENSG00000089009(gene)|ensembl:ENST00000202773(transcript)|ensembl:ENST00000424576(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:Q02878|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001307066.1|refseq:NP_001307067.1|refseq:NP_001307068.1|refseq:NP_001307069.1|refseq:NP_001307070.1|refseq:XP_016875270.1|refseq:XP_016875271.1|dip:DIP-27547N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:Y7fx3ToInzucV2QmI8KLSdHxai09606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P62847 intact:EBI-6150681 intact:EBI-354515|uniprotkb:P16632|uniprotkb:Q7Z3D1|uniprotkb:Q5T0P7|uniprotkb:Q5T0P8|uniprotkb:E7EPK6|ensembl:ENSP00000478869 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rs24_human(display_long)|uniprotkb:RPS24(gene name)|psi-mi:RPS24(display_short)|uniprotkb:Small ribosomal subunit protein eS24(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001135757.1|refseq:NP_001017.1|refseq:NP_001135755.1|refseq:NP_148982.1|ensembl:ENSG00000138326(gene)|ensembl:ENST00000613865(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR001976(Ribosomal protein S24e)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR018098|mint:P62847|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6XA1|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:M/qkRxabHx9PFaOM7EwKDOOwu7Q9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P62424 intact:EBI-6150681 intact:EBI-354172|uniprotkb:P11518|uniprotkb:Q5T8U4|ensembl:ENSP00000361076|ensembl:ENSP00000487443 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl7a_human(display_long)|uniprotkb:RPL7A(gene name)|psi-mi:RPL7A(display_short)|uniprotkb:SURF-3(gene name synonym)|uniprotkb:SURF3(gene name synonym)|uniprotkb:Surfeit locus protein 3(gene name synonym)|uniprotkb:PLA-X polypeptide(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_000963.1|dip:DIP-31502N|ensembl:ENSG00000148303(gene)|ensembl:ENSG00000280858(gene)|ensembl:ENST00000323345(transcript)|ensembl:ENST00000630979(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR001921(Ribosomal protein L7A)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:P62424|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|go:"GO:0005634"(nucleus)|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:shPtLmc+oabT/rSwho+tP1iJy4k9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P62937 intact:EBI-6150681 intact:EBI-437708|uniprotkb:P05092|uniprotkb:Q3KQW3|uniprotkb:Q6IBU5|uniprotkb:Q96IX3|uniprotkb:Q9BRU4|uniprotkb:Q9BTY9|uniprotkb:Q9UC61|uniprotkb:Q567Q0|ensembl:ENSP00000419425|uniprotkb:A8K220 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:ppia_human(display_long)|uniprotkb:Cyclophilin A(gene name synonym)|uniprotkb:Cyclosporin A-binding protein(gene name synonym)|uniprotkb:PPIA(gene name)|psi-mi:PPIA(display_short)|uniprotkb:CYPA(gene name synonym)|uniprotkb:Rotamase A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_066953.1|interpro:IPR029000|mint:P62937|rcsb pdb:1AK4|rcsb pdb:1AWQ|rcsb pdb:1AWR|rcsb pdb:1AWS|rcsb pdb:1AWT|rcsb pdb:1AWU|rcsb pdb:1AWV|rcsb pdb:1BCK|rcsb pdb:1CWA|rcsb pdb:1CWB|rcsb pdb:1CWC|rcsb pdb:1CWF|rcsb pdb:1CWH|rcsb pdb:1CWI|rcsb pdb:1CWJ|rcsb pdb:1CWK|rcsb pdb:1CWL|rcsb pdb:1CWM|interpro:IPR024936|rcsb pdb:1CWO|rcsb pdb:1FGL|rcsb pdb:2N0T|rcsb pdb:2RMA|rcsb pdb:1M63|rcsb pdb:2RMB|rcsb pdb:2X25|rcsb pdb:2X2A|rcsb pdb:2X2C|rcsb pdb:2X2D|rcsb pdb:1M9C|rcsb pdb:1M9D|rcsb pdb:1M9E|rcsb pdb:2XGY|rcsb pdb:3CYH|rcsb pdb:3CYS|rcsb pdb:3K0M|rcsb pdb:3K0N|rcsb pdb:3K0O|rcsb pdb:3K0P|rcsb pdb:3K0Q|rcsb pdb:3K0R|rcsb pdb:3ODI|rcsb pdb:3ODL|rcsb pdb:1M9F|rcsb pdb:3RDD|rcsb pdb:1M9X|rcsb pdb:1M9Y|rcsb pdb:4CYH|rcsb pdb:4IPZ|rcsb pdb:4N1M|rcsb pdb:4N1N|rcsb pdb:1MF8|rcsb pdb:4N1O|rcsb pdb:4N1P|rcsb pdb:4N1Q|rcsb pdb:1MIK|rcsb pdb:1NMK|rcsb pdb:1OCA|rcsb pdb:1RMH|rcsb pdb:1VBS|rcsb pdb:1VBT|rcsb pdb:1W8L|rcsb pdb:1W8M|rcsb pdb:1W8V|rcsb pdb:1YND|rcsb pdb:1ZKF|rcsb pdb:2ALF|rcsb pdb:2CPL|rcsb pdb:2CYH|rcsb pdb:2MS4|rcsb pdb:2MZU|rcsb pdb:4N1R|rcsb pdb:4N1S|rcsb pdb:4YUG|rcsb pdb:4YUH|refseq:NP_001287910.1|reactome:R-HSA-210991|reactome:R-HSA-6798695|reactome:R-HSA-8950505|reactome:R-HSA-2025928|ensembl:ENSG00000196262(gene)|ensembl:ENST00000468812(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006915"(apoptotic process)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016020"(membrane)|go:"GO:0019076"(viral release from host cell)|go:"GO:0030168"(platelet activation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0031982"(vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046790"(virion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060352"(cell adhesion molecule production)|go:"GO:0061944"(negative regulation of protein K48-linked ubiquitination)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903901"(negative regulation of viral life cycle)|go:"GO:1904399"(heparan sulfate binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|go:"GO:0005178"(integrin binding)|rcsb pdb:4YUI|rcsb pdb:4YUJ|rcsb pdb:4YUK|rcsb pdb:4YUL|rcsb pdb:4YUM|rcsb pdb:4YUN|rcsb pdb:4YUO|rcsb pdb:4YUP|rcsb pdb:5CYH|rcsb pdb:5F66|rcsb pdb:5FJB|rcsb pdb:5KUL|rcsb pdb:5KUN|rcsb pdb:5KUO|rcsb pdb:5KUQ|rcsb pdb:5KUR|rcsb pdb:5KUS|rcsb pdb:5KUU|rcsb pdb:5KUV|rcsb pdb:5KUW|rcsb pdb:5KUZ|rcsb pdb:5KV0|rcsb pdb:5KV1|rcsb pdb:5KV2|rcsb pdb:5KV3|rcsb pdb:5KV4|rcsb pdb:5KV5|rcsb pdb:5KV6|rcsb pdb:5KV7|rcsb pdb:5LUD|rcsb pdb:5NOQ|rcsb pdb:5NOR|rcsb pdb:5NOT|rcsb pdb:5NOU|rcsb pdb:5NOV|rcsb pdb:5NOW|rcsb pdb:5NOX|rcsb pdb:5NOY|rcsb pdb:5NOZ|rcsb pdb:5T9U|rcsb pdb:5T9W|rcsb pdb:5T9Z|rcsb pdb:5TA2|rcsb pdb:5TA4|rcsb pdb:5WC7|rcsb pdb:6BTA|rcsb pdb:6GJI|rcsb pdb:6GJJ|rcsb pdb:6GJL|rcsb pdb:6GJM|rcsb pdb:6GJN|rcsb pdb:6GJP|rcsb pdb:6GJR|rcsb pdb:6GJY|rcsb pdb:6GS6|rcsb pdb:6I42|rcsb pdb:6U5C|rcsb pdb:6U5D|rcsb pdb:6U5E|rcsb pdb:6U5G|rcsb pdb:6X3R|rcsb pdb:6X3Y|rcsb pdb:5NOS|rcsb pdb:6X4N|rcsb pdb:6X4O|rcsb pdb:6X4P|rcsb pdb:6X4Q|rcsb pdb:6Y9V|rcsb pdb:6Y9W|rcsb pdb:6Y9X|rcsb pdb:6Y9Y|rcsb pdb:6Y9Z|rcsb pdb:6ZDJ|rcsb pdb:7ABT|reactome:R-HSA-114608|reactome:R-HSA-162585|reactome:R-HSA-162588|reactome:R-HSA-162592|reactome:R-HSA-162594|reactome:R-HSA-164516|reactome:R-HSA-164525|reactome:R-HSA-173107|rcsb pdb:6X4M|reactome:R-HSA-175474|reactome:R-HSA-180689|dip:DIP-6080N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:dr4EVxcO+sqTPBqsQcydRn+rHoo9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P23396 intact:EBI-6150681 intact:EBI-351193|uniprotkb:Q498B5|uniprotkb:Q8NI95|uniprotkb:B2R7N5|ensembl:ENSP00000433821|ensembl:ENSP00000434643|ensembl:ENSP00000436971|uniprotkb:J3KN86 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rs3_human(display_long)|uniprotkb:RPS3(gene name)|psi-mi:RPS3(display_short)|uniprotkb:Small ribosomal subunit protein uS3(gene name synonym)|uniprotkb:OK/SW-cl.26(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_000996.2|ensembl:ENSG00000149273(gene)|ensembl:ENST00000524851(transcript)|ensembl:ENST00000527446(transcript)|ensembl:ENST00000531188(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR004044(K Homology, type 2)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|go:"GO:0071159"(NF-kappaB complex)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR018280|interpro:IPR036419|mint:P23396|rcsb pdb:1WH9|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|rcsb pdb:6QZP|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|refseq:NP_001243731.1|refseq:NP_001247436.1|refseq:NP_001247435.1|dip:DIP-33177N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:fsDW18AMR3YyEEIhMVcngYRWkps9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q6S8J3 intact:EBI-6150681 intact:EBI-4289913|uniprotkb:Q6S8J4|uniprotkb:Q6S8J8|uniprotkb:Q6S8J5|ensembl:ENSP00000439189|ensembl:ENSP00000507284 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:potee_human(display_long)|uniprotkb:POTEE(gene name)|psi-mi:POTEE(display_short)|uniprotkb:A26C1A(gene name synonym)|uniprotkb:POTE2(gene name synonym)|uniprotkb:ANKRD26-like family C member 1A(gene name synonym)|uniprotkb:Prostate, ovary, testis-expressed protein on chromosome 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) ensembl:ENSG00000188219(gene)|ensembl:ENST00000356920(transcript)|ensembl:ENST00000683005(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005615"(extracellular space)|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR002110(Ankyrin)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020683|interpro:IPR036770|interpro:IPR039497|interpro:IPR043129|reactome:R-HSA-9035034|interpro:IPR020902|refseq:NP_001077007.1|refseq:XP_016859650.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:LMuv4bmAG2/uPyH5LR9q+ickvWI9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P08865 intact:EBI-6150681 intact:EBI-354112|uniprotkb:Q6NSD1|uniprotkb:Q6NXQ8|uniprotkb:Q86VC0|uniprotkb:P11085|uniprotkb:P12030|uniprotkb:Q16471|uniprotkb:Q6IPD1|uniprotkb:Q6IPD2|ensembl:ENSP00000346067 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rssa_human(display_long)|uniprotkb:RPSA(gene name)|psi-mi:RPSA(display_short)|uniprotkb:LAMBR(gene name synonym)|uniprotkb:LAMR1(gene name synonym)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:Colon carcinoma laminin-binding protein(gene name synonym)|uniprotkb:NEM/1CHD4(gene name synonym)|uniprotkb:Multidrug resistance-associated protein MGr1-Ag(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_002286.2|refseq:NP_001291217.1|dip:DIP-32878N|ensembl:ENSG00000168028(gene)|ensembl:ENST00000301821(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0007155"(cell adhesion)|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZOJ|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|go:"GO:0043236"(laminin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P08865|rcsb pdb:3BCH|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:Jpv3I3G5C297fHfNwIqyB9Pf8/A9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P62241 intact:EBI-6150681 intact:EBI-351811|uniprotkb:Q6IRL7|uniprotkb:P09058|ensembl:ENSP00000379888 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rs8_human(display_long)|uniprotkb:RPS8(gene name)|psi-mi:RPS8(display_short)|uniprotkb:Small ribosomal subunit protein eS8(gene name synonym)|uniprotkb:OK/SW-cl.83(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001003.1|ensembl:ENSG00000142937(gene)|ensembl:ENST00000396651(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001047(Ribosomal protein S8e)|interpro:IPR018283|interpro:IPR022309|interpro:IPR042563|mint:P62241|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:6G5H|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975957|reactome:R-HSA-975956 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:3rpCBdQyRWR+TCKnupbnCp30jKE9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q71U36 intact:EBI-6150681 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q96KK5 intact:EBI-6150681 intact:EBI-6147668|ensembl:ENSP00000366679 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h2a1h_human(display_long)|uniprotkb:H2AC12(gene name)|psi-mi:H2AC12(display_short)|uniprotkb:H2A-clustered histone 12(gene name synonym)|uniprotkb:HIST1H2AH(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:Histone H2A/s(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_542163.1|dip:DIP-61699N|ensembl:ENSG00000274997(gene)|ensembl:ENST00000377459(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:Oa322n+evy8Cu0E9cWTEdYwQPKM9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P62899 intact:EBI-6150681 intact:EBI-1053664|intact:EBI-3867511|uniprotkb:B7Z4K2|uniprotkb:P12947|uniprotkb:Q53SQ5|uniprotkb:Q6LBJ6|uniprotkb:D3DVJ4|uniprotkb:Q6IRZ0|ensembl:ENSP00000264258|ensembl:ENSP00000386681 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl31_human(display_long)|uniprotkb:RPL31(gene name)|psi-mi:RPL31(display_short)|uniprotkb:Large ribosomal subunit protein eL31(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_000984.1|refseq:NP_001092047.1|refseq:NP_001093163.1|ensembl:ENSG00000071082(gene)|ensembl:ENST00000264258(transcript)|ensembl:ENST00000409733(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000054(Ribosomal protein L31e)|interpro:IPR020052|interpro:IPR023621|mint:P62899|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:77LFR7/2somk6blVogZf1XFdJLk9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P22061 intact:EBI-6150681 intact:EBI-353343|uniprotkb:Q14661|uniprotkb:Q16556|uniprotkb:Q5VYC1|uniprotkb:Q5VYC2|uniprotkb:Q93061|uniprotkb:Q96II9|uniprotkb:Q99625|uniprotkb:Q9BQV7|uniprotkb:Q9BQV8|uniprotkb:Q9NP03|uniprotkb:A8K109|intact:EBI-2551555|uniprotkb:J3KP72|ensembl:ENSP00000356348|ensembl:ENSP00000420813 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:pimt_human(display_long)|uniprotkb:PCMT1(gene name)|psi-mi:PCMT1(display_short)|uniprotkb:Protein-beta-aspartate methyltransferase(gene name synonym)|uniprotkb:Protein L-isoaspartyl/D-aspartyl methyltransferase(gene name synonym)|uniprotkb:L-isoaspartyl protein carboxyl methyltransferase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001238978.1|refseq:NP_001238982.1|ensembl:ENSG00000120265(gene)|ensembl:ENST00000367378(transcript)|ensembl:ENST00000464889(transcript)|go:"GO:0004719"("protein-L-isoaspartate (D-aspartate) O-methyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0030091"(protein repair)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000682("Protein-L-isoaspartate(D-aspartate) O-methyltransferase")|interpro:IPR029063|mint:P22061|rcsb pdb:1I1N|rcsb pdb:1KR5|reactome:R-HSA-5676934|refseq:NP_005380.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:wfsjVloc3sqDMXlvFAXQI6Fjilw9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q13243 intact:EBI-6150681 intact:EBI-720503|uniprotkb:O14797|uniprotkb:Q16662|uniprotkb:Q49AD6|uniprotkb:Q6FGE0|ensembl:ENSP00000377892|ensembl:ENSP00000451088|ensembl:ENSP00000452123 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:srsf5_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP40(gene name synonym)|uniprotkb:Delayed-early protein HRS(gene name synonym)|uniprotkb:SRSF5(gene name)|psi-mi:SRSF5(display_short)|uniprotkb:HRS(gene name synonym)|uniprotkb:SRP40(gene name synonym)|uniprotkb:SFRS5(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) go:"GO:0003729"(mRNA binding)|refseq:NP_001034554.1|refseq:NP_008856.2|refseq:NP_001307143.1|dip:DIP-46894N|ensembl:ENSG00000100650(gene)|ensembl:ENST00000394366(transcript)|ensembl:ENST00000553521(transcript)|ensembl:ENST00000557154(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035585|interpro:IPR035979|mint:Q13243|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|go:"GO:0005654"(nucleoplasm)|reactome:R-HSA-73856 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:q+kwVNXjDcA8o9hJ+BDF0S5ZSlY9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P62750 intact:EBI-6150681 intact:EBI-353254|uniprotkb:P29316|uniprotkb:Q92774|uniprotkb:P39024|uniprotkb:B2R5B2|ensembl:ENSP00000389103 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl23a_human(display_long)|uniprotkb:RPL23A(gene name)|psi-mi:RPL23A(display_short)|uniprotkb:Large ribosomal subunit protein uL23(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|refseq:NP_000975.2|ensembl:ENSG00000198242(gene)|ensembl:ENST00000422514(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904841"(TORC2 complex binding)|interpro:IPR001014(Ribosomal protein L23, conserved site)|interpro:IPR005633(Ribosomal protein L23/L25, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|interpro:IPR019985|mint:P62750|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:lA1ubRFO9/Tl54Z1dKUzoCKvpAo9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P61254 intact:EBI-6150681 intact:EBI-352405|uniprotkb:Q02877|uniprotkb:Q6IPY2|uniprotkb:B2R4F0|uniprotkb:D3DTR8|ensembl:ENSP00000462322|ensembl:ENSP00000463470|ensembl:ENSP00000463784|ensembl:ENSP00000498177 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl26_human(display_long)|uniprotkb:RPL26(gene name)|psi-mi:RPL26(display_short)|uniprotkb:Large ribosomal subunit protein uL24(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_000978.1|refseq:NP_001302459.1|refseq:NP_001302460.1|ensembl:ENST00000582556(transcript)|ensembl:ENST00000583011(transcript)|ensembl:ENST00000584164(transcript)|ensembl:ENST00000648839(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|ensembl:ENSG00000161970(gene)|go:"GO:0022626"(cytosolic ribosome)|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:1902164"(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:1902167"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1904803"(regulation of translation involved in cellular response to UV)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005756(Ribosomal protein L26, eukaryotic/archaeal)|interpro:IPR005824(KOW)|interpro:IPR005825(Ribosomal protein L24/L26, conserved site)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041988|mint:P61254|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|go:"GO:0034644"(cellular response to UV)|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|rcsb pdb:5LKS|reactome:R-HSA-156827|dip:DIP-33198N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:VAROWOFmYvolVgc/e5E1jAmNuaY9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P61247 intact:EBI-6150681 intact:EBI-352378|uniprotkb:P33443|uniprotkb:P49241|uniprotkb:B2R4D4|intact:EBI-3440915|uniprotkb:D3DP05|ensembl:ENSP00000346050 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rs3a_human(display_long)|uniprotkb:RPS3A(gene name)|psi-mi:RPS3A(display_short)|uniprotkb:MFTL(gene name synonym)|uniprotkb:FTE1(gene name synonym)|uniprotkb:v-fos transformation effector protein(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_000997.1|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:4V6X|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|ensembl:ENSG00000145425(gene)|ensembl:ENST00000274065(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030154"(cell differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001593(Ribosomal protein S3Ae)|interpro:IPR018281|interpro:IPR027500|mint:P61247|rcsb pdb:4UG0|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6OM7|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|dip:DIP-29408N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:g1TMzz8OFWEuhrRCoecj7KW0qTQ9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P61353 intact:EBI-6150681 intact:EBI-352760|uniprotkb:P08526|uniprotkb:Q4G0A9|ensembl:ENSP00000253788|ensembl:ENSP00000464813|ensembl:ENSP00000467587 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl27_human(display_long)|uniprotkb:RPL27(gene name)|psi-mi:RPL27(display_short)|uniprotkb:Large ribosomal subunit protein eL27(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OLF|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000979.1|ensembl:ENSG00000131469(gene)|ensembl:ENST00000253788(transcript)|ensembl:ENST00000589037(transcript)|ensembl:ENST00000589913(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:1904044"(response to aldosterone)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001141(Ribosomal protein L27e)|interpro:IPR005824(KOW)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018262|interpro:IPR038655|interpro:IPR041991|mint:P61353|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:TLWbAcdRKUb2ijDYjSUa1sbixis9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P18124 intact:EBI-6150681 intact:EBI-350806|uniprotkb:Q3KQU0|uniprotkb:Q15289|uniprotkb:Q5I0X1|uniprotkb:Q6IBM9|uniprotkb:A8K504|ensembl:ENSP00000339795 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl7_human(display_long)|uniprotkb:RPL7(gene name)|psi-mi:RPL7(display_short)|uniprotkb:Large ribosomal subunit protein uL30(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_000962.2|ensembl:ENSG00000147604(gene)|ensembl:ENST00000352983(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|mint:P18124|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72689 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:miVEaLOilDYcZXshxJlYbpnzwZ89606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P62917 intact:EBI-6150681 intact:EBI-438527|ensembl:ENSP00000262584|ensembl:ENSP00000378378|ensembl:ENSP00000433464|uniprotkb:P25120|uniprotkb:Q567Q7|uniprotkb:Q969V7|uniprotkb:Q9BWQ9|uniprotkb:A8K094|uniprotkb:D3DWN2 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl8_human(display_long)|uniprotkb:RPL8(gene name)|psi-mi:RPL8(display_short)|uniprotkb:Large ribosomal subunit protein uL2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) rcsb pdb:4CCN|rcsb pdb:4CCO|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4Y3O|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000161016(gene)|ensembl:ENST00000262584(transcript)|ensembl:ENST00000394920(transcript)|ensembl:ENST00000528957(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098794"(postsynapse)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR022666|interpro:IPR022669|interpro:IPR022671|interpro:IPR023672|mint:P62917|rcsb pdb:4CCM|refseq:NP_000964.1|refseq:NP_150644.1|refseq:NP_001304700.1|refseq:NP_001304711.1|dip:DIP-37967N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:+b/ORzdCy/nqFLsKRV9VhIZgdjg9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P62081 intact:EBI-6150681 intact:EBI-354360|uniprotkb:Q6IPH1|uniprotkb:P23821|uniprotkb:P24818|uniprotkb:Q57Z92|ensembl:ENSP00000385018|ensembl:ENSP00000385286|ensembl:ENSP00000495273|ensembl:ENSP00000496654|ensembl:ENSP00000496757 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rs7_human(display_long)|uniprotkb:RPS7(gene name)|psi-mi:RPS7(display_short)|uniprotkb:Small ribosomal subunit protein eS7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001002.1|ensembl:ENSG00000171863(gene)|ensembl:ENST00000403564(transcript)|ensembl:ENST00000406376(transcript)|ensembl:ENST00000462576(transcript)|ensembl:ENST00000645674(transcript)|ensembl:ENST00000646909(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030154"(cell differentiation)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000554(Ribosomal protein S7e)|mint:P62081|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6G4S - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:l4aG6I34lmzYhNapbdv2CAAwRwg9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P49207 intact:EBI-6150681 intact:EBI-1051893|uniprotkb:Q6FG66|uniprotkb:Q9BUZ2|ensembl:ENSP00000378160|ensembl:ENSP00000378162|ensembl:ENSP00000378163|ensembl:ENSP00000423316|ensembl:ENSP00000423983 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl34_human(display_long)|uniprotkb:RPL34(gene name)|psi-mi:RPL34(display_short)|uniprotkb:Large ribosomal subunit protein eL34(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_000986.2|refseq:NP_296374.1|refseq:NP_001306161.1|refseq:NP_001306163.1|refseq:NP_001306164.1|refseq:NP_001306165.1|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|rcsb pdb:6Y6X|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR008195(Ribosomal protein L34e)|interpro:IPR018065|mint:P49207|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|ensembl:ENSG00000109475(gene)|ensembl:ENST00000394665(transcript)|ensembl:ENST00000394667(transcript)|ensembl:ENST00000394668(transcript)|ensembl:ENST00000502534(transcript)|ensembl:ENST00000506397(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:NSGnIE6uSimeraPQ7ZZ+xRugABg9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q7L7L0 intact:EBI-6150681 intact:EBI-5325551|ensembl:ENSP00000355656|ensembl:ENSP00000493926|uniprotkb:B2R4S4 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h2a3_human(display_long)|uniprotkb:H2AW(gene name)|psi-mi:H2AW(display_short)|uniprotkb:HIST3H2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) ensembl:ENSG00000181218(gene)|ensembl:ENSG00000284841(gene)|ensembl:ENST00000366695(transcript)|refseq:NP_254280.1|ensembl:ENST00000645741(transcript)|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-5689603|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q7L7L0|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000786"(nucleosome)|dip:DIP-48936N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:t0RdR1SmUtmwRjtCS3uTyLGqSUI9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q969Q0 intact:EBI-6150681 intact:EBI-2877705|ensembl:ENSP00000346012|uniprotkb:Q3B7A5 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl36l_human(display_long)|uniprotkb:RPL36AL(gene name)|psi-mi:RPL36AL(display_short)|uniprotkb:Large ribosomal subunit protein eL42-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) ensembl:ENSG00000165502(gene)|ensembl:ENST00000298289(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000552(Ribosomal protein L44e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:Q969Q0|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-9633012|refseq:NP_000992.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:+jT5oFy79StEavkvHz6j/36g/qg9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P39023 intact:EBI-6150681 intact:EBI-1056348|uniprotkb:Q15548|uniprotkb:Q5I0G0|uniprotkb:B2RDV9|ensembl:ENSP00000346001 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl3_human(display_long)|uniprotkb:RPL3(gene name)|psi-mi:RPL3(display_short)|uniprotkb:HIV-1 TAR RNA-binding protein B(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL3(gene name synonym)|uniprotkb:OK/SW-cl.32(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_000958.1|ensembl:ENSG00000100316(gene)|ensembl:ENST00000216146(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|mint:P39023|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:j3MVAYfO/bziJBPmH4zCFqFskZ89606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P62753 intact:EBI-6150681 intact:EBI-356625|uniprotkb:P08227|uniprotkb:P10660|uniprotkb:Q4VBY7|uniprotkb:Q8N6Z7|ensembl:ENSP00000369757 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rs6_human(display_long)|uniprotkb:RPS6(gene name)|psi-mi:RPS6(display_short)|uniprotkb:Phosphoprotein NP33(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS6(gene name synonym)|uniprotkb:OK/SW-cl.2(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001001.2|reactome:R-HSA-166208|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR014401(Ribosomal protein S6, eukaryotic)|interpro:IPR018282|mint:P62753|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6F4P|rcsb pdb:6F4Q|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|ensembl:ENSG00000137154(gene)|ensembl:ENST00000380394(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001890"(placenta development)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022605"(mammalian oogenesis stage)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030425"(dendrite)|go:"GO:0031929"(TOR signaling)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048821"(erythrocyte development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001377(Ribosomal protein S6e)|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|dip:DIP-31507N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:beDuXCIqL99V9JlVfpzx7MdpH689606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:O95793 intact:EBI-6150681 intact:EBI-358174|uniprotkb:Q6GTM4|uniprotkb:Q9H5B5|intact:EBI-366174|uniprotkb:Q9H5B4|uniprotkb:Q9Y3Q2|uniprotkb:A8K9Z4|ensembl:ENSP00000360922|uniprotkb:E1P5Y1|uniprotkb:E1P608|uniprotkb:Q5JW29 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:stau1_human(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001309856.1|refseq:NP_001309858.1|refseq:NP_001309859.1|refseq:NP_001032405.1|refseq:NP_004593.2|refseq:NP_059346.2|refseq:NP_059347.2|refseq:NP_059348.2|refseq:NP_001306063.1|refseq:NP_001306064.1|ensembl:ENSG00000124214(gene)|ensembl:ENST00000371856(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|refseq:XP_005260584.1|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:O95793|rcsb pdb:4DKK|rcsb pdb:6HTU|rcsb pdb:6SDW|rcsb pdb:6SDY - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:uYjbWja/hG5M/3likHLe00Z2FgY9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P63267 intact:EBI-6150681 intact:EBI-297795|uniprotkb:P12718|uniprotkb:Q504R1|uniprotkb:Q6FI22|ensembl:ENSP00000295137|ensembl:ENSP00000386857|uniprotkb:B2R7E7|uniprotkb:D6W5H8|uniprotkb:B4E315|uniprotkb:E9PG30 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:acth_human(display_long)|uniprotkb:ACTG2(gene name)|psi-mi:ACTG2(display_short)|uniprotkb:ACTA3(gene name synonym)|uniprotkb:ACTSG(gene name synonym)|uniprotkb:Smooth muscle gamma-actin(gene name synonym)|uniprotkb:Gamma-2-actin(gene name synonym)|uniprotkb:Alpha-actin-3(gene name synonym)|uniprotkb:ACTL3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0032982"(myosin filament)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:6JAT|reactome:R-HSA-445355|go:"GO:0010628"(positive regulation of gene expression)|ensembl:ENST00000345517(transcript)|ensembl:ENST00000409624(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|ensembl:ENSG00000163017(gene)|refseq:NP_001186822.1|refseq:NP_001606.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:tp0JsXhrGsRl5i4Wg2dyaPGUPxA9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P67809 intact:EBI-6150681 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P06733 intact:EBI-6150681 intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:RmP7cr55H8ylcgBOEyivwljIE+09606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q6FI13 intact:EBI-6150681 intact:EBI-353620|uniprotkb:P20670|uniprotkb:B2R5F0|ensembl:ENSP00000358155|ensembl:ENSP00000475814 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h2a2a_human(display_long)|uniprotkb:H2AC18(gene name)|psi-mi:H2AC18(display_short)|uniprotkb:H2AC19(gene name)|psi-mi:H2AC19(display_short)|uniprotkb:H2A-clustered histone 18(gene name synonym)|uniprotkb:H2A-clustered histone 19(gene name synonym)|uniprotkb:H2AFO(gene name synonym)|uniprotkb:HIST2H2AA(gene name synonym)|uniprotkb:HIST2H2AA3(gene name synonym)|uniprotkb:HIST2H2AA4(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/o(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001035807.1|refseq:NP_003507.1|ensembl:ENSG00000203812(gene)|ensembl:ENSG00000272196(gene)|ensembl:ENST00000369159(transcript)|ensembl:ENST00000607355(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6Y5D|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|dip:DIP-33167N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:PMuIm2XMN5q4wk+wYJ94mmnCe4w9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P49458 intact:EBI-6150681 intact:EBI-350743|uniprotkb:Q6NVX0|uniprotkb:Q8WTW0|ensembl:ENSP00000305230|uniprotkb:A8K0N0 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:srp09_human(display_long)|uniprotkb:SRP9(gene name)|psi-mi:SRP9(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) rcsb pdb:4UYJ|refseq:NP_001123912.1|refseq:NP_003124.1|ensembl:ENSG00000143742(gene)|ensembl:ENST00000304786(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005785"(signal recognition particle receptor complex)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0045900"(negative regulation of translational elongation)|interpro:IPR008832(Signal recognition particle, SRP9 subunit)|interpro:IPR009018(Signal recognition particle, SRP9/SRP14 subunit)|interpro:IPR039432|interpro:IPR039914|mint:P49458|rcsb pdb:1E8O|rcsb pdb:1E8S|rcsb pdb:1RY1|rcsb pdb:4UYK|rcsb pdb:5AOX|rcsb pdb:7NFX|reactome:R-HSA-1799339|dip:DIP-6151N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:Y33fEeeXnma9oF7Fzs6zEGQjVBU9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q9BTM1 intact:EBI-6150681 intact:EBI-4398590|uniprotkb:Q9NV63|ensembl:ENSP00000373730|ensembl:ENSP00000438553 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h2aj_human(display_long)|uniprotkb:H2AJ(gene name)|psi-mi:H2AJ(display_short)|uniprotkb:H2AFJ(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_808760.1|ensembl:ENSG00000246705(gene)|ensembl:ENST00000389078(transcript)|ensembl:ENST00000544848(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:4EDU|rcsb pdb:6K60|rcsb pdb:6KVD|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-8939236 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:g6br63FeM17yJRfQI3GnmoM0vbc9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q93077 intact:EBI-6150681 intact:EBI-725259|uniprotkb:O00775|uniprotkb:O00776|uniprotkb:O00777|uniprotkb:O00778|uniprotkb:Q540R1|uniprotkb:B2R4F7|ensembl:ENSP00000321389|ensembl:ENSP00000367022|ensembl:ENSP00000473534 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h2a1c_human(display_long)|uniprotkb:H2AC6(gene name)|psi-mi:H2AC6(display_short)|uniprotkb:H2A-clustered histone 6(gene name synonym)|uniprotkb:H2AFL(gene name synonym)|uniprotkb:HIST1H2AC(gene name synonym)|uniprotkb:Histone H2A/l(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_003503.1|ensembl:ENSG00000180573(gene)|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENST00000314088(transcript)|ensembl:ENST00000377791(transcript)|ensembl:ENST00000602637(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|rcsb pdb:6C0W|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:7A08|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|interpro:IPR032458 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:m00IdooZksbNGKHSsaVvGFVpcko9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P62701 intact:EBI-6150681 intact:EBI-354303|uniprotkb:P12631|uniprotkb:P12750|uniprotkb:P27576|uniprotkb:Q14727|uniprotkb:P55831|uniprotkb:Q6IPY4|ensembl:ENSP00000362744 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rs4x_human(display_long)|uniprotkb:RPS4X(gene name)|psi-mi:RPS4X(display_short)|uniprotkb:CCG2(gene name synonym)|uniprotkb:RPS4(gene name synonym)|uniprotkb:SCAR(gene name synonym)|uniprotkb:Single copy abundant mRNA protein(gene name synonym)|uniprotkb:SCR10(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_000998.1|rcsb pdb:6OLI|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000198034(gene)|ensembl:ENST00000316084(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000876(Ribosomal protein S4e)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005824(KOW)|interpro:IPR013843(Ribosomal protein S4e, N-terminal)|interpro:IPR013845(Ribosomal protein S4e, central)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR018199|interpro:IPR032277|interpro:IPR036986|interpro:IPR038237|interpro:IPR041982|mint:P62701|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|go:"GO:0045727"(positive regulation of translation)|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:2ZuLXqBSDkK0CtN3mnIDoFAR8yI9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q9NR30 intact:EBI-6150681 intact:EBI-357942|uniprotkb:Q13436|uniprotkb:Q5VX41|uniprotkb:Q68D35|uniprotkb:B2RDL0|intact:EBI-2555822|ensembl:ENSP00000346120 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:ddx21_human(display_long)|uniprotkb:DDX21(gene name)|psi-mi:DDX21(display_short)|uniprotkb:Nucleolar RNA helicase II(gene name synonym)|uniprotkb:Nucleolar RNA helicase Gu(gene name synonym)|uniprotkb:RH II/Gu(gene name synonym)|uniprotkb:Gu-alpha(gene name synonym)|uniprotkb:DEAD box protein 21(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_004719.2|dip:DIP-32941N|refseq:NP_001243839.1|ensembl:ENSG00000165732(gene)|ensembl:ENST00000354185(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0030515"(snoRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062176"(R-loop disassembly)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012562(GUCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR035979|mint:Q9NR30|rcsb pdb:2M3D|rcsb pdb:6L5L|rcsb pdb:6L5M|rcsb pdb:6L5N|rcsb pdb:6L5O|reactome:R-HSA-5250924|reactome:R-HSA-6791226|go:"GO:0005829"(cytosol) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:NSmxvs3DBWvKpVDEAHIpqy7/b6w9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q00839 intact:EBI-6150681 intact:EBI-351126|uniprotkb:O75507|uniprotkb:Q8N174|uniprotkb:Q96HY9|uniprotkb:Q9BQ09|ensembl:ENSP00000491215 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:hnrpu_human(display_long)|uniprotkb:HNRNPU(gene name)|psi-mi:HNRNPU(display_short)|uniprotkb:SAFA(gene name synonym)|uniprotkb:U21.1(gene name synonym)|uniprotkb:HNRPU(gene name synonym)|uniprotkb:p120(gene name synonym)|uniprotkb:pp120(gene name synonym)|uniprotkb:C1orf199(gene name synonym)|uniprotkb:GRIP120(gene name synonym)|uniprotkb:Nuclear p120 ribonucleoprotein(gene name synonym)|uniprotkb:Scaffold-attachment factor A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_004492.2|refseq:NP_114032.2|ensembl:ENSG00000153187(gene)|ensembl:ENST00000640218(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:1990498"(mitotic spindle microtubule)|go:"GO:0098577"(inactive sex chromosome)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR026745|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q00839|rcsb pdb:1ZRJ|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990280"(RNA localization to chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006396"(RNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008143"("poly(A) binding")|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0017130"("poly(C) RNA binding")|go:"GO:0030496"(midbody)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|refseq:XP_016856604.1|refseq:XP_016856605.1|refseq:XP_016856606.1|dip:DIP-684N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:n73PY0Vis+D5Iq0q77h5Ck2V4789606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q16777 intact:EBI-6150681 intact:EBI-5325566|ensembl:ENSP00000332194|uniprotkb:Q6DRA7|uniprotkb:Q8IUE5 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h2a2c_human(display_long)|uniprotkb:H2AC20(gene name)|psi-mi:H2AC20(display_short)|uniprotkb:H2A-clustered histone 20(gene name synonym)|uniprotkb:H2AFQ(gene name synonym)|uniprotkb:HIST2H2AC(gene name synonym)|uniprotkb:Histone H2A-GL101(gene name synonym)|uniprotkb:Histone H2A/q(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-5689603|ensembl:ENSG00000184260(gene)|ensembl:ENST00000331380(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q16777|rcsb pdb:6Y5E|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|refseq:NP_003508.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:Wejrpp9wK3GvA4ahJDVyEH+cwlQ9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P55795 intact:EBI-6150681 intact:EBI-352823|ensembl:ENSP00000361927|uniprotkb:Q9HHA7|uniprotkb:A1L400 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:hnrh2_human(display_long)|uniprotkb:HNRNPH2(gene name)|psi-mi:HNRNPH2(display_short)|uniprotkb:FTP3(gene name synonym)|uniprotkb:HNRPH2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein H'(gene name synonym)|uniprotkb:FTP-3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) ensembl:ENSG00000126945(gene)|ensembl:ENST00000316594(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P55795|rcsb pdb:1WEZ|rcsb pdb:1WG5|rcsb pdb:6DG1|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001027565.1|refseq:NP_062543.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:811j5syFsbk/QSaZv/ag9QsFUEQ9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P05165 intact:EBI-6150681 intact:EBI-2211679|uniprotkb:B4DPF9|uniprotkb:C9JPQ8|uniprotkb:B4DKY8|uniprotkb:Q15979|intact:EBI-2803938|uniprotkb:Q8WXQ7|ensembl:ENSP00000365462 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:pcca_human(display_long)|uniprotkb:PCCA(gene name)|psi-mi:PCCA(display_short)|uniprotkb:"Propanoyl-CoA:carbon dioxide ligase subunit alpha"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_000273.2|refseq:NP_001121164.1|refseq:NP_001171475.1|dip:DIP-57493N|ensembl:ENSG00000175198(gene)|ensembl:ENST00000376285(transcript)|go:"GO:0004658"(propionyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0009374"(biotin binding)|go:"GO:0016421"(CoA carboxylase activity)|go:"GO:0019626"(short-chain fatty acid catabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR041265|mint:P05165|rcsb pdb:2CQY|rcsb pdb:2JKU|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-71032 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:IR3jXR6XjVwD8WRNlN4N5+AOk049606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P62910 intact:EBI-6150681 intact:EBI-438408|ensembl:ENSP00000380156|ensembl:ENSP00000380158|ensembl:ENSP00000388674|ensembl:ENSP00000416429|uniprotkb:P02433|uniprotkb:B2R4Q3 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl32_human(display_long)|uniprotkb:RPL32(gene name)|psi-mi:RPL32(display_short)|uniprotkb:Large ribosomal subunit protein eL32(gene name synonym)|uniprotkb:PP9932(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) ensembl:ENSG00000144713(gene)|ensembl:ENST00000396953(transcript)|ensembl:ENST00000396957(transcript)|ensembl:ENST00000429711(transcript)|ensembl:ENST00000435983(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR001515(Ribosomal protein L32e)|interpro:IPR018263|interpro:IPR036351|mint:P62910|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000985.1|refseq:NP_001007074.1|refseq:NP_001007075.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:8Yhph2ETzWYd07yJcq1cVqsSRjo9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P08238 intact:EBI-6150681 intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:wOsW7C10v2oMsM+REE38K6PAan09606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P62277 intact:EBI-6150681 intact:EBI-351850|uniprotkb:P19116|uniprotkb:Q02546|uniprotkb:Q29200|uniprotkb:Q498Y0|uniprotkb:B2R549|ensembl:ENSP00000435777 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rs13_human(display_long)|uniprotkb:RPS13(gene name)|psi-mi:RPS13(display_short)|uniprotkb:Small ribosomal subunit protein uS15(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001008.1|ensembl:ENSG00000110700(gene)|ensembl:ENST00000525634(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR000589(Ribosomal protein S15)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR012606(Ribosomal protein S13/S15, N-terminal)|interpro:IPR023029|mint:P62277|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6OM7|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:GmlWYkXKxX6YwpEtzNABb+ZcytI9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q93079 intact:EBI-6150681 intact:EBI-352469|uniprotkb:Q4VB74|uniprotkb:B2R541|ensembl:ENSP00000479169 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h2b1h_human(display_long)|uniprotkb:H2BC9(gene name)|psi-mi:H2BC9(display_short)|uniprotkb:H2B-clustered histone 9(gene name synonym)|uniprotkb:H2BFJ(gene name synonym)|uniprotkb:HIST1H2BH(gene name synonym)|uniprotkb:Histone H2B.j(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_003515.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|ensembl:ENSG00000275713(gene)|ensembl:ENST00000619466(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0097677"(STAT family protein binding)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:W+7KkrtV9xv7ELLxmJFnI4LQoME9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P46777 intact:EBI-6150681 intact:EBI-358018|ensembl:ENSP00000359345|uniprotkb:Q53HH6|uniprotkb:Q9H3F4|uniprotkb:Q32LZ3 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl5_human(display_long)|uniprotkb:RPL5(gene name)|psi-mi:RPL5(display_short)|uniprotkb:Large ribosomal subunit protein uL18(gene name synonym)|uniprotkb:MSTP030(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0045202"(synapse)|ensembl:ENSG00000122406(gene)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|ensembl:ENST00000370321(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0010628"(positive regulation of gene expression)|refseq:NP_000960.2|dip:DIP-31152N|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR005485(Ribosomal protein L5, eukaryotic)|interpro:IPR025607|mint:P46777|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:rs+zAc+IPrEqv7DHNcy2GIkQkfY9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P33778 intact:EBI-6150681 intact:EBI-357986|uniprotkb:Q4KN36|ensembl:ENSP00000482674 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h2b1b_human(display_long)|uniprotkb:H2BC3(gene name)|psi-mi:H2BC3(display_short)|uniprotkb:H2B-clustered histone 3(gene name synonym)|uniprotkb:H2BFF(gene name synonym)|uniprotkb:HIST1H2BB(gene name synonym)|uniprotkb:Histone H2B.1(gene name synonym)|uniprotkb:Histone H2B.f(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_066406.1|dip:DIP-47505N|ensembl:ENSG00000276410(gene)|ensembl:ENST00000615966(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P33778|rcsb pdb:3X1S|rcsb pdb:3X1U|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:l15lrchv4onuihbdZ+yWJQd35Ss9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q8NCM8 intact:EBI-6150681 intact:EBI-2512957|ensembl:ENSP00000364887|uniprotkb:Q7Z363|uniprotkb:O00432|uniprotkb:Q9HAE4|uniprotkb:Q8N977|uniprotkb:Q3C1U8|uniprotkb:Q6ZMX7|uniprotkb:Q16693|uniprotkb:Q6ZUM6|uniprotkb:Q4AC93|uniprotkb:Q92815|intact:EBI-2860086 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:dyhc2_human(display_long)|uniprotkb:DYNC2H1(gene name)|psi-mi:DYNC2H1(display_short)|uniprotkb:DYH1B(gene name synonym)|uniprotkb:KIAA1997(gene name synonym)|uniprotkb:Cytoplasmic dynein 2 heavy chain(gene name synonym)|uniprotkb:Dynein cytoplasmic heavy chain 2(gene name synonym)|uniprotkb:Dynein heavy chain isotype 1B(gene name synonym)|uniprotkb:Dynein heavy chain 11(gene name synonym)|uniprotkb:DHC1B(gene name synonym)|uniprotkb:DHC2(gene name synonym)|uniprotkb:DNCH2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) interpro:IPR027417|interpro:IPR035699|interpro:IPR035706|interpro:IPR041228|interpro:IPR041658|interpro:IPR042219|interpro:IPR042222|interpro:IPR042228|interpro:IPR043157|interpro:IPR043160|rcsb pdb:4RH7|reactome:R-HSA-5610787|reactome:R-HSA-5620924|ensembl:ENSG00000187240(gene)|ensembl:ENST00000375735(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007030"(Golgi organization)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0016485"(protein processing)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0030286"(dynein complex)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030900"(forebrain development)|go:"GO:0031514"(motile cilium)|go:"GO:0035721"(intraciliary retrograde transport)|go:"GO:0045177"(apical part of cell)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097542"(ciliary tip)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004273(Dynein heavy chain)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|interpro:IPR013594(Dynein heavy chain, N-terminal region 1)|interpro:IPR013602(Dynein heavy chain, N-terminal region 2)|interpro:IPR024317|interpro:IPR024743|interpro:IPR026815|interpro:IPR026983|refseq:NP_001073932.1|refseq:NP_001368.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:c6bU2mT13JkjPNR9maL9+/R3IIg9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P42766 intact:EBI-6150681 intact:EBI-356819|uniprotkb:Q4VBY5|uniprotkb:Q9BYF4|uniprotkb:Q5JTN5|uniprotkb:Q6IBC7|uniprotkb:Q96QJ7|uniprotkb:A8K4V7|ensembl:ENSP00000259469 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl35_human(display_long)|uniprotkb:RPL35(gene name)|psi-mi:RPL35(display_short)|uniprotkb:Large ribosomal subunit protein uL29(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_009140.1|ensembl:ENSG00000136942(gene)|ensembl:ENST00000348462(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001854(Ribosomal protein L29)|interpro:IPR018254|interpro:IPR036049|mint:P42766|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:jhzt7gCff2vdUb1Ff/VTBF698Pg9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P62913 intact:EBI-6150681 intact:EBI-354380|uniprotkb:P25121|uniprotkb:P39026|uniprotkb:Q8TDH2|uniprotkb:Q9Y674|ensembl:ENSP00000496250 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl11_human(display_long)|uniprotkb:RPL11(gene name)|psi-mi:RPL11(display_short)|uniprotkb:CLL-associated antigen KW-12(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_000966.2|refseq:NP_001186731.1|ensembl:ENSG00000142676(gene)|ensembl:ENST00000643754(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006605"(protein targeting)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR002132(Ribosomal protein L5)|interpro:IPR020929|interpro:IPR022803|interpro:IPR031309|interpro:IPR031310|mint:P62913|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4XXB|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y6X - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:xt8XhDkfQPoH4DIPr0gC+ll766Q9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P61313 intact:EBI-6150681 intact:EBI-443462|ensembl:ENSP00000309334|ensembl:ENSP00000346867|ensembl:ENSP00000388529|ensembl:ENSP00000416692|ensembl:ENSP00000483260|ensembl:ENSP00000493759|uniprotkb:Q642I1|uniprotkb:Q9H2E5|uniprotkb:P39030|uniprotkb:P41051|uniprotkb:Q6IPX6|uniprotkb:Q8WYP2|uniprotkb:Q96C44|uniprotkb:Q5U0C0|intact:EBI-2877712 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl15_human(display_long)|uniprotkb:RPL15(gene name)|psi-mi:RPL15(display_short)|uniprotkb:EC45(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL15(gene name synonym)|uniprotkb:TCBAP0781(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) ensembl:ENSG00000174748(gene)|ensembl:ENST00000307839(transcript)|ensembl:ENST00000354811(transcript)|ensembl:ENST00000413699(transcript)|ensembl:ENST00000415719(transcript)|ensembl:ENST00000611050(transcript)|ensembl:ENST00000644185(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|interpro:IPR000439(Ribosomal protein L15e)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR020925|interpro:IPR024794|mint:P61313|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_002939.2|refseq:NP_001240308.1|refseq:NP_001240309.1|refseq:NP_001240311.1|refseq:NP_001240312.1|refseq:NP_001240313.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:wllGpJicgC5uwkZV6e4QRwDcrBo9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P23527 intact:EBI-6150681 intact:EBI-1642161|uniprotkb:Q3KPI7|uniprotkb:Q8TCV6|ensembl:ENSP00000477527 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h2b1o_human(display_long)|uniprotkb:H2BC17(gene name)|psi-mi:H2BC17(display_short)|uniprotkb:H2B-clustered histone 17(gene name synonym)|uniprotkb:H2BFH(gene name synonym)|uniprotkb:H2BFN(gene name synonym)|uniprotkb:HIST1H2BO(gene name synonym)|uniprotkb:Histone H2B.2(gene name synonym)|uniprotkb:Histone H2B.n(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_003518.2|ensembl:ENSG00000274641(gene)|ensembl:ENST00000616182(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P23527|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:vetsoCf1s6GUePoGq1wMLwz8obg9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P07195 intact:EBI-6150681 intact:EBI-358748|ensembl:ENSP00000229319|ensembl:ENSP00000379386 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:ldhb_human(display_long)|uniprotkb:LDHB(gene name)|psi-mi:LDHB(display_short)|uniprotkb:LDH heart subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001167568.1|refseq:NP_002291.1|refseq:NP_001302466.1|ensembl:ENSG00000111716(gene)|ensembl:ENST00000350669(transcript)|ensembl:ENST00000396076(transcript)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|mint:P07195|rcsb pdb:1I0Z|rcsb pdb:1T2F|reactome:R-HSA-70268 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:umdj6fjSO7+4SM9Hrl1/K2EiKls9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P84243 intact:EBI-6150681 intact:EBI-120658|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q5VV55|uniprotkb:Q5VV56|uniprotkb:Q66I33|uniprotkb:Q9V3W4|ensembl:ENSP00000254810|ensembl:ENSP00000355778|ensembl:ENSP00000355780|ensembl:ENSP00000355781|ensembl:ENSP00000465813|ensembl:ENSP00000466020|ensembl:ENSP00000468714|ensembl:ENSP00000499275|ensembl:ENSP00000499385|ensembl:ENSP00000499800 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h33_human(display_long)|uniprotkb:H3-3A(gene name)|psi-mi:H3-3A(display_short)|uniprotkb:H3-3B(gene name)|psi-mi:H3-3B(display_short)|uniprotkb:H3.3A(gene name synonym)|uniprotkb:H3.3B(gene name synonym)|uniprotkb:H3F3(gene name synonym)|uniprotkb:H3F3A(gene name synonym)|uniprotkb:H3F3B(gene name synonym)|uniprotkb:PP781(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_002098.1|refseq:NP_005315.1|rcsb pdb:4H9N|rcsb pdb:3QL9|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:3QLA|rcsb pdb:3QLC|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4L58|rcsb pdb:4N4I|rcsb pdb:3WTP|rcsb pdb:4O62|rcsb pdb:4QQ4|rcsb pdb:4TMP|rcsb pdb:4GNE|rcsb pdb:4GNF|rcsb pdb:4U7T|rcsb pdb:4GNG|rcsb pdb:4W5A|rcsb pdb:4GU0|rcsb pdb:4GUR|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:4GUS|rcsb pdb:4GY5|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5JA4|rcsb pdb:5JJY|ensembl:ENSG00000132475(gene)|ensembl:ENSG00000163041(gene)|rcsb pdb:5JLB|rcsb pdb:5KDM|rcsb pdb:5X7X|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6HGT|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6J9J|rcsb pdb:6PZV|rcsb pdb:6QXZ|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6U04|rcsb pdb:7A08|reactome:R-HSA-427413|rcsb pdb:7CIZ|reactome:R-HSA-5250924|reactome:R-HSA-5334118|rcsb pdb:7CJ0|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-983231|rcsb pdb:7CWH|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-427359|reactome:R-HSA-427389|ensembl:ENST00000254810(transcript)|ensembl:ENST00000366813(transcript)|ensembl:ENST00000366815(transcript)|ensembl:ENST00000366816(transcript)|ensembl:ENST00000586607(transcript)|ensembl:ENST00000587560(transcript)|ensembl:ENST00000589599(transcript)|ensembl:ENST00000655399(transcript)|ensembl:ENST00000661429(transcript)|ensembl:ENST00000666609(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P84243|rcsb pdb:2L43|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3AV2|rcsb pdb:3JVK|rcsb pdb:3MUK|rcsb pdb:3MUL|dip:DIP-40046N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:cRqA5/IBNfIbbxAnbwLqzXip20I9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P46776 intact:EBI-6150681 intact:EBI-350581|uniprotkb:B2R4B3|ensembl:ENSP00000346015 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl27a_human(display_long)|uniprotkb:RPL27A(gene name)|psi-mi:RPL27A(display_short)|uniprotkb:Large ribosomal subunit protein uL15(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_000981.1|ensembl:ENSG00000166441(gene)|ensembl:ENST00000314138(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001196(Ribosomal protein L15)|interpro:IPR021131|interpro:IPR027386|interpro:IPR030878|interpro:IPR036227|mint:P46776|rcsb pdb:4BXF|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72706|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6IP6|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6OM7|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:6IP5|dip:DIP-33121N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:tUezMQBw+SWmLYq8M0pkLCF8vO89606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q99877 intact:EBI-6150681 intact:EBI-744423|uniprotkb:Q494S8|uniprotkb:Q96FB7|uniprotkb:B2R5L4|ensembl:ENSP00000446031|ensembl:ENSP00000483903 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h2b1n_human(display_long)|uniprotkb:H2BC15(gene name)|psi-mi:H2BC15(display_short)|uniprotkb:H2BFD(gene name synonym)|uniprotkb:HIST1H2BN(gene name synonym)|uniprotkb:Histone H2B.d(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_003511.1|ensembl:ENSG00000233822(gene)|ensembl:ENST00000449538(transcript)|ensembl:ENST00000612898(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:nGZETothwO57PuE11M5ogikaZkM9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q02543 intact:EBI-6150681 intact:EBI-350523|ensembl:ENSP00000222247 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl18a_human(display_long)|uniprotkb:RPL18A(gene name)|psi-mi:RPL18A(display_short)|uniprotkb:Large ribosomal subunit protein eL20(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_000971.1|interpro:IPR021138|interpro:IPR023573|interpro:IPR028877|mint:Q02543|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|go:"GO:0097327"(response to antineoplastic agent)|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|ensembl:ENSG00000105640(gene)|ensembl:ENST00000222247(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|rcsb pdb:6ZME|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:O9XdW7Let2GcJpJLVuUtatVVv1I9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P35268 intact:EBI-6150681 intact:EBI-354533|intact:EBI-1055963|uniprotkb:Q6IBD1|uniprotkb:B2R495|ensembl:ENSP00000346088 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl22_human(display_long)|uniprotkb:RPL22(gene name)|psi-mi:RPL22(display_short)|uniprotkb:Heparin-binding protein HBp15(gene name synonym)|uniprotkb:Epstein-Barr virus small RNA-associated protein(gene name synonym)|uniprotkb:EBER-associated protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL22(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_000974.1|ensembl:ENSG00000116251(gene)|ensembl:ENST00000234875(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008201"(heparin binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0045182"(translation regulator activity)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099577"(regulation of translation at presynapse, modulating synaptic transmission)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002671(Ribosomal protein L22e)|interpro:IPR038526|mint:P35268|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|reactome:R-HSA-72706|rcsb pdb:6Z6L|rcsb pdb:6Z6M|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:0TVillnqDkHmdTwxIedAJCVAdzY9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:Q9NZI8 intact:EBI-6150681 intact:EBI-1053892|uniprotkb:C9JT33|ensembl:ENSP00000290341 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:if2b1_human(display_long)|uniprotkb:ZBP1(gene name synonym)|uniprotkb:IGF-II mRNA-binding protein 1(gene name synonym)|uniprotkb:Coding region determinant-binding protein(gene name synonym)|uniprotkb:VICKZ family member 1(gene name synonym)|uniprotkb:IGF2BP1(gene name)|psi-mi:IGF2BP1(display_short)|uniprotkb:Zipcode-binding protein 1(gene name synonym)|uniprotkb:CRDBP(gene name synonym)|uniprotkb:VICKZ1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_006537.3|refseq:NP_001153895.1|ensembl:ENSG00000159217(gene)|ensembl:ENST00000290341(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007399"(nervous system development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010610"(regulation of mRNA stability involved in response to stress)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022013"(pallium cell proliferation in forebrain)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0140059"(dendrite arborization)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034837|interpro:IPR034842|interpro:IPR035979|interpro:IPR036612|mint:Q9NZI8|rcsb pdb:3KRM|rcsb pdb:6QEY|reactome:R-HSA-428359|reactome:R-HSA-5687128|dip:DIP-38139N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:3Ps/PWWYr0WpYcx3G/AOiQEj+vc9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P57053 intact:EBI-6150681 intact:EBI-2880265|ensembl:ENSP00000481622|uniprotkb:A0AVF9|uniprotkb:Q5R2W0 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:h2bfs_human(display_long)|uniprotkb:H2BS1(gene name)|psi-mi:H2BS1(display_short)|uniprotkb:H2B.S histone 1(gene name synonym)|uniprotkb:H2BFS(gene name synonym)|uniprotkb:Histone H2B.s(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) ensembl:ENSG00000234289(gene)|ensembl:ENST00000599962(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0021762"(substantia nigra development)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-427359|refseq:XP_006723981.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:x8Ryb6Tm0nfhcmsoTX5h5ZRsN7g9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P46782 intact:EBI-6150681 intact:EBI-350569|uniprotkb:Q96BN0|uniprotkb:B2R4T2|ensembl:ENSP00000196551|ensembl:ENSP00000470114|ensembl:ENSP00000472985 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rs5_human(display_long)|uniprotkb:RPS5(gene name)|psi-mi:RPS5(display_short)|uniprotkb:Small ribosomal subunit protein uS7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001000.2|rcsb pdb:6OLZ|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6Z6M|rcsb pdb:6XA1|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6Y0G|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:5FLX|rcsb pdb:6OLG|rcsb pdb:6OLI|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72706|ensembl:ENSG00000083845(gene)|ensembl:ENST00000196551(transcript)|ensembl:ENST00000596046(transcript)|ensembl:ENST00000601521(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000235(Ribosomal protein S7)|interpro:IPR005716(Ribosomal protein S7, eukaryotic/archaeal)|interpro:IPR020606|interpro:IPR023798|interpro:IPR036823|mint:P46782|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:5AJ0|reactome:R-HSA-72702 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:SoCJdf2InngZZtlz5qD1k5CEfEo9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:P62829 intact:EBI-6150681 intact:EBI-353303|uniprotkb:P23131|uniprotkb:Q3SWV7|uniprotkb:P24048|uniprotkb:Q29246|uniprotkb:Q6P5S1|ensembl:ENSP00000377865|ensembl:ENSP00000420311 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:rl23_human(display_long)|uniprotkb:RPL23(gene name)|psi-mi:RPL23(display_short)|uniprotkb:60S ribosomal protein L17(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|reactome:R-HSA-9010553|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|refseq:NP_000969.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000218(Ribosomal protein L14b/L23e)|interpro:IPR019972|interpro:IPR036853|mint:P62829|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|ensembl:ENSG00000125691(gene)|ensembl:ENST00000394332(transcript)|ensembl:ENST00000479035(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0005730"(nucleolus)|dip:DIP-33156N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:TiSVU2W4+lkwf12eb4+vG6IFlZA9606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04487 uniprotkb:O43390 intact:EBI-6150681 intact:EBI-713419|uniprotkb:S4R3J4|uniprotkb:Q5TEH1|ensembl:ENSP00000304405|ensembl:ENSP00000363741|ensembl:ENSP00000489252|ensembl:ENSP00000489371|uniprotkb:Q9BV64|uniprotkb:Q2L7G6 psi-mi:rnb_hhv11(display_long)|uniprotkb:Vmw21(gene name synonym)|uniprotkb:US11(gene name)|psi-mi:US11(display_short) psi-mi:hnrpr_human(display_long)|uniprotkb:HNRPR(gene name synonym)|uniprotkb:HNRNPR(gene name)|psi-mi:HNRNPR(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10299(hhv11)|taxid:10299("Human herpesvirus 1 (strain 17) (HHV-1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157560|imex:IM-17331-46 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_009137147.1|mint:P04487|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039521"(suppression by virus of host autophagy)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044196"(host cell nucleolus)|go:"GO:0046792"(suppression by virus of host cell cycle arrest) refseq:NP_001095868.1|refseq:XP_005245768.1|ensembl:ENSG00000125944(gene)|ensembl:ENSG00000282958(gene)|ensembl:ENST00000302271(transcript)|ensembl:ENST00000374612(transcript)|ensembl:ENST00000634263(transcript)|ensembl:ENST00000634766(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043679"(axon terminus)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034411|interpro:IPR035979|mint:O43390|rcsb pdb:2DK2|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR041337|refseq:NP_005817.1|refseq:XP_011538773.1|refseq:NP_001284549.1|refseq:XP_016855497.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:J3LGVy033NJ6MG95uzmCY2bCyZY10299 rogid:UiOaRbnMd1S2FthR4RWltyq6xT49606 intact-crc:8330316705D9E2C2 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:Q02539 intact:EBI-6151115 intact:EBI-932603|uniprotkb:Q3MJ34|ensembl:ENSP00000244573 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h11_human(display_long)|uniprotkb:H1-1(gene name)|psi-mi:H1-1(display_short)|uniprotkb:H1F1(gene name synonym)|uniprotkb:HIST1H1A(gene name synonym)|uniprotkb:Histone H1a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L refseq:NP_005316.1|ensembl:ENSG00000124610(gene)|ensembl:ENST00000244573(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q02539|reactome:R-HSA-140342|reactome:R-HSA-2559584 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:4u8P8jFM3onWx43+SxL320urjhk9606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:Q99878 intact:EBI-6151115 intact:EBI-6147676|uniprotkb:Q5JXQ5|uniprotkb:A2RUU6|ensembl:ENSP00000328484 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a1j_human(display_long)|uniprotkb:H2AC14(gene name)|psi-mi:H2AC14(display_short)|uniprotkb:H2AFE(gene name synonym)|uniprotkb:HIST1H2AJ(gene name synonym)|uniprotkb:Histone H2A/e(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L refseq:NP_066544.1|ensembl:ENSG00000276368(gene)|ensembl:ENST00000333151(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:tS29VG3PpglHaYbu0w5z7pGvYyI9606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:Q7L7L0 intact:EBI-6151115 intact:EBI-5325551|ensembl:ENSP00000355656|ensembl:ENSP00000493926|uniprotkb:B2R4S4 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a3_human(display_long)|uniprotkb:H2AW(gene name)|psi-mi:H2AW(display_short)|uniprotkb:HIST3H2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L ensembl:ENSG00000181218(gene)|ensembl:ENSG00000284841(gene)|ensembl:ENST00000366695(transcript)|refseq:NP_254280.1|ensembl:ENST00000645741(transcript)|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-5689603|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q7L7L0|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000786"(nucleosome)|dip:DIP-48936N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:t0RdR1SmUtmwRjtCS3uTyLGqSUI9606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:P27348 intact:EBI-6151115 intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081|ensembl:ENSP00000371267 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L refseq:NP_006817.1|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|ensembl:ENSG00000134308(gene)|ensembl:ENST00000238081(transcript)|ensembl:ENST00000381844(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|dip:DIP-27584N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:Q6FI13 intact:EBI-6151115 intact:EBI-353620|uniprotkb:P20670|uniprotkb:B2R5F0|ensembl:ENSP00000358155|ensembl:ENSP00000475814 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a2a_human(display_long)|uniprotkb:H2AC18(gene name)|psi-mi:H2AC18(display_short)|uniprotkb:H2AC19(gene name)|psi-mi:H2AC19(display_short)|uniprotkb:H2A-clustered histone 18(gene name synonym)|uniprotkb:H2A-clustered histone 19(gene name synonym)|uniprotkb:H2AFO(gene name synonym)|uniprotkb:HIST2H2AA(gene name synonym)|uniprotkb:HIST2H2AA3(gene name synonym)|uniprotkb:HIST2H2AA4(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/o(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L refseq:NP_001035807.1|refseq:NP_003507.1|ensembl:ENSG00000203812(gene)|ensembl:ENSG00000272196(gene)|ensembl:ENST00000369159(transcript)|ensembl:ENST00000607355(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6Y5D|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|dip:DIP-33167N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:PMuIm2XMN5q4wk+wYJ94mmnCe4w9606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:P12277 intact:EBI-6151115 intact:EBI-357706|uniprotkb:Q2LE07|uniprotkb:A8K236|uniprotkb:B2R5R4|uniprotkb:Q6FG40|uniprotkb:Q9UC66|ensembl:ENSP00000299198 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:kcrb_human(display_long)|uniprotkb:CKB(gene name)|psi-mi:CKB(display_short)|uniprotkb:CKBB(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:Brain creatine kinase(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L refseq:NP_001814.2|go:"GO:0005829"(cytosol)|ensembl:ENSG00000166165(gene)|ensembl:ENST00000348956(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12277|rcsb pdb:3B6R|rcsb pdb:3DRB|rcsb pdb:3DRE|rcsb pdb:6V9H|go:"GO:0021762"(substantia nigra development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|reactome:R-HSA-71288|reactome:R-HSA-9696264|dip:DIP-52968N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:WLRnU8sRUfJQoaPY0edGi9xiR+g9606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:O00505 intact:EBI-6151115 intact:EBI-358297|intact:EBI-28976892|ensembl:ENSP00000261667|uniprotkb:O00191|uniprotkb:O43195|uniprotkb:Q96AA7|uniprotkb:Q5JVM9|intact:EBI-742146|uniprotkb:Q8IYQ9 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:ima4_human(display_long)|uniprotkb:KPNA3(gene name)|psi-mi:KPNA3(display_short)|uniprotkb:QIP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym)|uniprotkb:SRP1-gamma(gene name synonym)|uniprotkb:Importin alpha Q2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L ensembl:ENSG00000102753(gene)|ensembl:ENST00000261667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043657"(host cell)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000225(Armadillo)|refseq:NP_002258.2|ensembl:ENSP00000261667|dip:DIP-27586N|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00505|reactome:R-HSA-1169408|reactome:R-HSA-168276 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:kx/oTYWMYG7dhwJHvr1POLD6FTU9606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:Q96KK5 intact:EBI-6151115 intact:EBI-6147668|ensembl:ENSP00000366679 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a1h_human(display_long)|uniprotkb:H2AC12(gene name)|psi-mi:H2AC12(display_short)|uniprotkb:H2A-clustered histone 12(gene name synonym)|uniprotkb:HIST1H2AH(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:Histone H2A/s(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L refseq:NP_542163.1|dip:DIP-61699N|ensembl:ENSG00000274997(gene)|ensembl:ENST00000377459(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:Oa322n+evy8Cu0E9cWTEdYwQPKM9606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:P62805 intact:EBI-6151115 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:P22626 intact:EBI-6151115 intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:P61981 intact:EBI-6151115 intact:EBI-359832|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q6FH52|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSP00000306330 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:1433g_human(display_long)|uniprotkb:YWHAG(gene name)|psi-mi:YWHAG(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L refseq:NP_036611.2|ensembl:ENSG00000170027(gene)|ensembl:ENST00000307630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006605"(protein targeting)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61981|rcsb pdb:2B05|rcsb pdb:3UZD|rcsb pdb:4E2E|rcsb pdb:4J6S|rcsb pdb:4O46|rcsb pdb:5D3E|rcsb pdb:6A5S|rcsb pdb:6BYJ|rcsb pdb:6BYL|rcsb pdb:6BZD|rcsb pdb:6FEL|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y4K|rcsb pdb:6Y6B|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-9614399|dip:DIP-33406N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:u1cd71h0RPgTOEMrQVhOelsxWnM9606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:P20671 intact:EBI-6151115 intact:EBI-4407441|uniprotkb:A0PK91|uniprotkb:P57754|uniprotkb:Q6FGY6|ensembl:ENSP00000341094 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a1d_human(display_long)|uniprotkb:H2AC7(gene name)|psi-mi:H2AC7(display_short)|uniprotkb:H2AFG(gene name synonym)|uniprotkb:HIST1H2AD(gene name synonym)|uniprotkb:Histone H2A.3(gene name synonym)|uniprotkb:Histone H2A/g(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L refseq:NP_066409.1|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000196866(gene)|ensembl:ENST00000341023(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:5GT3|rcsb pdb:6KBB|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:Geraq+dGw3pvAAhgzzXQnYxDOOw9606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:P52630 intact:EBI-6151115 intact:EBI-1546963|uniprotkb:Q16430|uniprotkb:Q16431|uniprotkb:Q9UDL4|intact:EBI-10989287|uniprotkb:B4DLC7|uniprotkb:G3V2M6|ensembl:ENSP00000315768 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:stat2_human(display_long)|uniprotkb:p113(gene name synonym)|uniprotkb:STAT2(gene name)|psi-mi:STAT2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L refseq:NP_005410.1|refseq:NP_938146.1|dip:DIP-38511N|ensembl:ENSG00000170581(gene)|ensembl:ENST00000314128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0090140"(regulation of mitochondrial fission)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022756|interpro:IPR035854|interpro:IPR036535|interpro:IPR036860|mint:P52630|rcsb pdb:2KA4|rcsb pdb:6UX2|rcsb pdb:6WCZ|reactome:R-HSA-8854691|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9679191 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:uA0lxm5vmrLClQRP7NItd0/u4Ko9606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:Q16777 intact:EBI-6151115 intact:EBI-5325566|ensembl:ENSP00000332194|uniprotkb:Q6DRA7|uniprotkb:Q8IUE5 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a2c_human(display_long)|uniprotkb:H2AC20(gene name)|psi-mi:H2AC20(display_short)|uniprotkb:H2A-clustered histone 20(gene name synonym)|uniprotkb:H2AFQ(gene name synonym)|uniprotkb:HIST2H2AC(gene name synonym)|uniprotkb:Histone H2A-GL101(gene name synonym)|uniprotkb:Histone H2A/q(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-5689603|ensembl:ENSG00000184260(gene)|ensembl:ENST00000331380(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q16777|rcsb pdb:6Y5E|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|refseq:NP_003508.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:Wejrpp9wK3GvA4ahJDVyEH+cwlQ9606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:P04908 intact:EBI-6151115 intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:4Qno1mMYZB6FdNoojrzulWLVq849606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:P22492 intact:EBI-6151115 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:Q6T4R5 intact:EBI-6151115 intact:EBI-6147838|uniprotkb:Q5J7Q1|uniprotkb:Q68DR5|uniprotkb:Q5J7Q0|uniprotkb:B7ZVX8|uniprotkb:E2DH69|ensembl:ENSP00000502262 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:nhs_human(display_long)|uniprotkb:NHS(gene name)|psi-mi:NHS(display_short)|uniprotkb:Congenital cataracts and dental anomalies protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L refseq:NP_001278796.1|refseq:NP_001278797.1|refseq:NP_001129496.1|refseq:NP_938011.1|ensembl:ENSG00000188158(gene)|ensembl:ENST00000676302(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|interpro:IPR024845|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:HqtL7E5pe3UkCCbArDU0XY+HAW49606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:P62258 intact:EBI-6151115 intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:Q93077 intact:EBI-6151115 intact:EBI-725259|uniprotkb:O00775|uniprotkb:O00776|uniprotkb:O00777|uniprotkb:O00778|uniprotkb:Q540R1|uniprotkb:B2R4F7|ensembl:ENSP00000321389|ensembl:ENSP00000367022|ensembl:ENSP00000473534 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a1c_human(display_long)|uniprotkb:H2AC6(gene name)|psi-mi:H2AC6(display_short)|uniprotkb:H2A-clustered histone 6(gene name synonym)|uniprotkb:H2AFL(gene name synonym)|uniprotkb:HIST1H2AC(gene name synonym)|uniprotkb:Histone H2A/l(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L refseq:NP_003503.1|ensembl:ENSG00000180573(gene)|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENST00000314088(transcript)|ensembl:ENST00000377791(transcript)|ensembl:ENST00000602637(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|rcsb pdb:6C0W|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:7A08|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|interpro:IPR032458 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:m00IdooZksbNGKHSsaVvGFVpcko9606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:P63104 intact:EBI-6151115 intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:P11021 intact:EBI-6151115 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:P31946 intact:EBI-6151115 intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:Q14974 intact:EBI-6151115 intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:P42224 intact:EBI-6151115 intact:EBI-1057697|uniprotkb:Q53S88|uniprotkb:Q53XW4|uniprotkb:B2RCA0|uniprotkb:Q9UDL5|uniprotkb:A8K989|uniprotkb:D2KFR8|uniprotkb:Q68D00|uniprotkb:D3DPI7|ensembl:ENSP00000354394|ensembl:ENSP00000386244|ensembl:ENSP00000388240|ensembl:ENSP00000438703 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:stat1_human(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)|uniprotkb:Transcription factor ISGF-3 components p91/p84(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L refseq:NP_009330.1|refseq:NP_644671.1|rcsb pdb:1YVL|rcsb pdb:2KA6|rcsb pdb:3WWT|reactome:R-HSA-1059683|reactome:R-HSA-1169408|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8939902|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9013508|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-909733|rcsb pdb:1BF5|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-912694|refseq:XP_006712781.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016922"(nuclear receptor binding)|ensembl:ENSG00000115415(gene)|ensembl:ENST00000361099(transcript)|ensembl:ENST00000409465(transcript)|ensembl:ENST00000415035(transcript)|ensembl:ENST00000540176(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051607"(defense response to virus)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0061326"(renal tubule development)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022752|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|interpro:IPR035859|interpro:IPR036535|interpro:IPR036860|interpro:IPR038295|mint:P42224|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042393"(histone binding)|dip:DIP-46140N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:a2ZnhdFZkctbjaXLpsYNJ3q5Cv49606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:P31942 intact:EBI-6151115 intact:EBI-711437|uniprotkb:Q9NPI4|uniprotkb:Q9UFU4|uniprotkb:Q9Y4J5|uniprotkb:Q9BSX1|uniprotkb:Q9NP53|uniprotkb:Q9NP96|uniprotkb:Q9NPA7|ensembl:ENSP00000265866|uniprotkb:A8K682|uniprotkb:B3KRE1 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:hnrh3_human(display_long)|uniprotkb:HNRNPH3(gene name)|psi-mi:HNRNPH3(display_short)|uniprotkb:HNRPH3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein 2H9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L ensembl:ENSG00000096746(gene)|ensembl:ENST00000265866(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034969|interpro:IPR034970|interpro:IPR035979|mint:P31942|refseq:NP_036339.1|refseq:NP_067676.2|refseq:NP_001309363.1|refseq:NP_001309365.1|refseq:NP_001309366.1|refseq:NP_001309367.1|refseq:NP_001309368.1|refseq:NP_001309369.1|refseq:NP_001309370.1|refseq:NP_001309374.1|refseq:NP_001309375.1|refseq:NP_001309376.1|refseq:NP_001309377.1|refseq:NP_001309378.1|refseq:XP_016871657.1|refseq:XP_016871658.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:iJGBIhPXnQIIFQmgxWB1WjwVXSY9606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:Q9BTM1 intact:EBI-6151115 intact:EBI-4398590|uniprotkb:Q9NV63|ensembl:ENSP00000373730|ensembl:ENSP00000438553 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2aj_human(display_long)|uniprotkb:H2AJ(gene name)|psi-mi:H2AJ(display_short)|uniprotkb:H2AFJ(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L refseq:NP_808760.1|ensembl:ENSG00000246705(gene)|ensembl:ENST00000389078(transcript)|ensembl:ENST00000544848(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:4EDU|rcsb pdb:6K60|rcsb pdb:6KVD|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-8939236 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:g6br63FeM17yJRfQI3GnmoM0vbc9606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:P0C0S8 intact:EBI-6151115 intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:P12036 intact:EBI-6151115 intact:EBI-2880271|uniprotkb:Q9UQ14|uniprotkb:Q9UJS7|uniprotkb:Q96HF8|uniprotkb:B4DYY4|ensembl:ENSP00000311997 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:nfh_human(display_long)|uniprotkb:NEFH(gene name)|psi-mi:NEFH(display_short)|uniprotkb:KIAA0845(gene name synonym)|uniprotkb:NFH(gene name synonym)|uniprotkb:200 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament triplet H protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L refseq:NP_066554.2|ensembl:ENSG00000100285(gene)|ensembl:ENST00000310624(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005883"(neurofilament)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0061564"(axon development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR010790(Protein of unknown function DUF1388)|interpro:IPR018039|interpro:IPR033183|interpro:IPR039008|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:TXMrn6SWBHIYQY1loZfVvMo9PtU9606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C7 uniprotkb:O00629 intact:EBI-6151115 intact:EBI-396343|uniprotkb:O00190|intact:EBI-28976443|ensembl:ENSP00000334373|uniprotkb:A8K4S6|uniprotkb:D3DNM2 psi-mi:w_nipav(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:ima3_human(display_long)|uniprotkb:KPNA4(gene name)|psi-mi:KPNA4(display_short)|uniprotkb:QIP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-4(gene name synonym)|uniprotkb:Importin alpha Q1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:121791(nipav)|taxid:121791(Nipah virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6157992|imex:IM-17331-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0C1C7|interpro:IPR025909|interpro:IPR035430|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6BVV|rcsb pdb:6BW0|rcsb pdb:6W0L refseq:NP_002259.1|ensembl:ENSG00000186432(gene)|ensembl:ENST00000334256(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00629|rcsb pdb:4UAE|rcsb pdb:5TBK|rcsb pdb:5XZX|rcsb pdb:6BVV|rcsb pdb:6BVZ|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|rcsb pdb:6WX8|rcsb pdb:7JJL|reactome:R-HSA-1169408|reactome:R-HSA-168276|ensembl:ENSP00000334373|dip:DIP-32982N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:4vQtryx+6eJtmQGs6euvhJ7xLPI121791 rogid:/cng/xZ42E2juzHNOpuQTP+amx89606 intact-crc:A15F84AC38262171|rigid:tLCS9mL+466nKMPmN5n1e2XOa4c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PNE5 uniprotkb:O14654 intact:EBI-6151213 intact:EBI-356594|ensembl:ENSP00000505547 psi-mi:q6pne5_9infa(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short) psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:270485(h5n1-thailand)|taxid:270485("Influenza A virus (A/chicken/Nakorn-Patom/Thailand/CU-K2/2004") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158085|imex:IM-17331-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:ZDZjhxFFqpmwf6GtJxkX8FTURSY270485 rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606 intact-crc:B5A9C48D2E4EB102|rigid:w2RvjsFp7kgJyUHKR2kmGVmg86o false tandem tag:?-?|sufficient binding region:1-215 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PNE5 uniprotkb:O00459 intact:EBI-6151213 intact:EBI-346930|uniprotkb:Q5EAT5|uniprotkb:Q9UPH9|intact:EBI-28974273|ensembl:ENSP00000222254 psi-mi:q6pne5_9infa(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short) psi-mi:p85b_human(display_long)|uniprotkb:PIK3R2(gene name)|psi-mi:PIK3R2(display_short)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:270485(h5n1-thailand)|taxid:270485("Influenza A virus (A/chicken/Nakorn-Patom/Thailand/CU-K2/2004") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158085|imex:IM-17331-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSP00000222254|refseq:NP_005018.1|dip:DIP-31811N|ensembl:ENSG00000105647(gene)|ensembl:ENST00000222254(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|rcsb pdb:6OX7|rcsb pdb:6U28|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-186763|reactome:R-HSA-198203|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|mint:O00459|rcsb pdb:2KT1|rcsb pdb:2XS6|rcsb pdb:3MTT|rcsb pdb:3O5Z|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-210993|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9013409 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:ZDZjhxFFqpmwf6GtJxkX8FTURSY270485 rogid:Ij0WS0eKPwShgFWQc7OEss7AcAU9606 intact-crc:B5A9C48D2E4EB102|rigid:w2RvjsFp7kgJyUHKR2kmGVmg86o false tandem tag:?-?|sufficient binding region:1-215 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PNE5 uniprotkb:Q08211 intact:EBI-6151213 intact:EBI-352022|intact:EBI-1058470|uniprotkb:Q5VY62|uniprotkb:Q6PD69|uniprotkb:Q99556|uniprotkb:B2RNV4|uniprotkb:Q05CI5|uniprotkb:Q12803|uniprotkb:Q32Q22|ensembl:ENSP00000356520 psi-mi:q6pne5_9infa(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short) psi-mi:dhx9_human(display_long)|uniprotkb:DHX9(gene name)|psi-mi:DHX9(display_short)|uniprotkb:DDX9(gene name synonym)|uniprotkb:NDH2(gene name synonym)|uniprotkb:DExH-box helicase 9(gene name synonym)|uniprotkb:RNA helicase A(gene name synonym)|uniprotkb:LKP(gene name synonym)|uniprotkb:Nuclear DNA helicase II(gene name synonym)|uniprotkb:DEAH box protein 9(gene name synonym)|uniprotkb:Leukophysin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:270485(h5n1-thailand)|taxid:270485("Influenza A virus (A/chicken/Nakorn-Patom/Thailand/CU-K2/2004") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158085|imex:IM-17331-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001348.2|dip:DIP-31504N|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033679"(3'-5' DNA/RNA helicase activity)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045142"(triplex DNA binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0097165"(nuclear stress granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1905172"(RISC complex binding)|go:"GO:1905538"(polysome binding)|go:"GO:1905698"(positive regulation of polysome binding)|go:"GO:1990518"(single-stranded 3'-5' DNA helicase activity)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000765"(regulation of cytoplasmic translation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR044445|interpro:IPR044446|interpro:IPR044447|mint:Q08211|rcsb pdb:3LLM|rcsb pdb:3VYX|rcsb pdb:3VYY|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-72163|go:"GO:1904973"(positive regulation of viral translation)|ensembl:ENSG00000135829(gene)|ensembl:ENST00000367549(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006260"(DNA replication)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0016604"(nuclear body) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:ZDZjhxFFqpmwf6GtJxkX8FTURSY270485 rogid:b0VP2Frtvwa9WbYVMwB6TbV2uGU9606 intact-crc:B5A9C48D2E4EB102|rigid:w2RvjsFp7kgJyUHKR2kmGVmg86o false tandem tag:?-?|sufficient binding region:1-215 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PNE5 uniprotkb:O43390 intact:EBI-6151213 intact:EBI-713419|uniprotkb:S4R3J4|uniprotkb:Q5TEH1|ensembl:ENSP00000304405|ensembl:ENSP00000363741|ensembl:ENSP00000489252|ensembl:ENSP00000489371|uniprotkb:Q9BV64|uniprotkb:Q2L7G6 psi-mi:q6pne5_9infa(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short) psi-mi:hnrpr_human(display_long)|uniprotkb:HNRPR(gene name synonym)|uniprotkb:HNRNPR(gene name)|psi-mi:HNRNPR(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:270485(h5n1-thailand)|taxid:270485("Influenza A virus (A/chicken/Nakorn-Patom/Thailand/CU-K2/2004") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158085|imex:IM-17331-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001095868.1|refseq:XP_005245768.1|ensembl:ENSG00000125944(gene)|ensembl:ENSG00000282958(gene)|ensembl:ENST00000302271(transcript)|ensembl:ENST00000374612(transcript)|ensembl:ENST00000634263(transcript)|ensembl:ENST00000634766(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043679"(axon terminus)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034411|interpro:IPR035979|mint:O43390|rcsb pdb:2DK2|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR041337|refseq:NP_005817.1|refseq:XP_011538773.1|refseq:NP_001284549.1|refseq:XP_016855497.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:ZDZjhxFFqpmwf6GtJxkX8FTURSY270485 rogid:UiOaRbnMd1S2FthR4RWltyq6xT49606 intact-crc:B5A9C48D2E4EB102|rigid:w2RvjsFp7kgJyUHKR2kmGVmg86o false tandem tag:?-?|sufficient binding region:1-215 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PNE5 uniprotkb:O60506 intact:EBI-6151213 intact:EBI-1024357|uniprotkb:Q53H05|uniprotkb:Q5TCG2|uniprotkb:Q8IW78|uniprotkb:Q8N599|uniprotkb:Q96LC1|uniprotkb:Q96LC2|uniprotkb:Q9Y583|uniprotkb:Q5TCG3|uniprotkb:E1P501|uniprotkb:E1P502|ensembl:ENSP00000358635|ensembl:ENSP00000503783|ensembl:ENSP00000504706 psi-mi:q6pne5_9infa(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short) psi-mi:hnrpq_human(display_long)|uniprotkb:Synaptotagmin-binding, cytoplasmic RNA-interacting protein(gene name synonym)|uniprotkb:Glycine- and tyrosine-rich RNA-binding protein(gene name synonym)|uniprotkb:NS1-associated protein 1(gene name synonym)|uniprotkb:SYNCRIP(gene name)|psi-mi:SYNCRIP(display_short)|uniprotkb:HNRPQ(gene name synonym)|uniprotkb:NSAP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:270485(h5n1-thailand)|taxid:270485("Influenza A virus (A/chicken/Nakorn-Patom/Thailand/CU-K2/2004") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158085|imex:IM-17331-48 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001153145.1|refseq:NP_001153146.1|refseq:NP_001153147.1|refseq:NP_001240700.1|refseq:NP_001153148.1|refseq:NP_001153149.1|refseq:NP_006363.4|ensembl:ENSG00000135316(gene)|ensembl:ENST00000369622(transcript)|ensembl:ENST00000676688(transcript)|ensembl:ENST00000678355(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034544|interpro:IPR034548|interpro:IPR035979|interpro:IPR041337|mint:O60506|rcsb pdb:2DGU|rcsb pdb:2MXT|rcsb pdb:2NBB|rcsb pdb:6KOR|refseq:XP_016865667.1|refseq:XP_005248694.1|dip:DIP-35540N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:ZDZjhxFFqpmwf6GtJxkX8FTURSY270485 rogid:2rDkXIp/wWzTOoVtN7Bd3uqZo689606 intact-crc:B5A9C48D2E4EB102|rigid:w2RvjsFp7kgJyUHKR2kmGVmg86o false tandem tag:?-?|sufficient binding region:1-215 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:P68431 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-79722|ensembl:ENSP00000352252|ensembl:ENSP00000358160|ensembl:ENSP00000366999|ensembl:ENSP00000480826|ensembl:ENSP00000482271|ensembl:ENSP00000483283|ensembl:ENSP00000484095|ensembl:ENSP00000484638|ensembl:ENSP00000484658|ensembl:ENSP00000484841|ensembl:ENSP00000489282|intact:EBI-1560041|uniprotkb:A0PJT7|uniprotkb:P02295|uniprotkb:P02296|uniprotkb:P16106|uniprotkb:Q6ISV8|uniprotkb:Q6NWP8|uniprotkb:Q6NWP9|uniprotkb:Q6NXU4|uniprotkb:Q71DJ3|uniprotkb:Q93081|uniprotkb:A5PLR1 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:h31_human(display_long)|uniprotkb:H3FA(gene name synonym)|uniprotkb:H3FL(gene name synonym)|uniprotkb:H3FD(gene name synonym)|uniprotkb:H3FI(gene name synonym)|uniprotkb:H3FH(gene name synonym)|uniprotkb:H3FK(gene name synonym)|uniprotkb:H3FF(gene name synonym)|uniprotkb:H3FJ(gene name synonym)|uniprotkb:H3FB(gene name synonym)|uniprotkb:Histone H3/a(gene name synonym)|uniprotkb:Histone H3/b(gene name synonym)|uniprotkb:Histone H3/c(gene name synonym)|uniprotkb:Histone H3/d(gene name synonym)|uniprotkb:Histone H3/f(gene name synonym)|uniprotkb:Histone H3/h(gene name synonym)|uniprotkb:Histone H3/i(gene name synonym)|uniprotkb:Histone H3/j(gene name synonym)|uniprotkb:Histone H3/k(gene name synonym)|uniprotkb:Histone H3/l(gene name synonym)|uniprotkb:H3C1(gene name)|psi-mi:H3C1(display_short)|uniprotkb:HIST1H3A(gene name synonym)|uniprotkb:H3C2(gene name)|psi-mi:H3C2(display_short)|uniprotkb:HIST1H3B(gene name synonym)|uniprotkb:H3C3(gene name)|psi-mi:H3C3(display_short)|uniprotkb:H3FC HIST1H3C(gene name synonym)|uniprotkb:H3C4(gene name)|psi-mi:H3C4(display_short)|uniprotkb:HIST1H3D(gene name synonym)|uniprotkb:H3C6(gene name)|psi-mi:H3C6(display_short)|uniprotkb:HIST1H3E(gene name synonym)|uniprotkb:H3C7(gene name)|psi-mi:H3C7(display_short)|uniprotkb:HIST1H3F(gene name synonym)|uniprotkb:H3C8(gene name)|psi-mi:H3C8(display_short)|uniprotkb:HIST1H3G(gene name synonym)|uniprotkb:H3C10(gene name)|psi-mi:H3C10(display_short)|uniprotkb:HIST1H3H(gene name synonym)|uniprotkb:H3C11(gene name)|psi-mi:H3C11(display_short)|uniprotkb:HIST1H3I(gene name synonym)|uniprotkb:H3C12(gene name)|psi-mi:H3C12(display_short)|uniprotkb:HIST1H3J(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) rcsb pdb:4TN7|rcsb pdb:4U68|rcsb pdb:4UP0|rcsb pdb:4UY4|rcsb pdb:4X3K|rcsb pdb:4Y6L|rcsb pdb:4YHP|rcsb pdb:4YHZ|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z0R|rcsb pdb:4Z2M|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:4QBS|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B31|rcsb pdb:5C11|rcsb pdb:5C13|rcsb pdb:5C3I|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5D6Y|rcsb pdb:5DAH|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5FFV|rcsb pdb:5GH9|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5HJB|rcsb pdb:5HJC|rcsb pdb:5HJD|rcsb pdb:5HYN|rcsb pdb:5IQL|rcsb pdb:5J3V|rcsb pdb:5J9S|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5B2J|rcsb pdb:5JRG|rcsb pdb:5KJH|rcsb pdb:5KJI|rcsb pdb:5KKL|rcsb pdb:5LUG|rcsb pdb:5M5G|rcsb pdb:5MR8|rcsb pdb:5NNC|rcsb pdb:5OY3|rcsb pdb:5SVX|rcsb pdb:5SVY|rcsb pdb:5SZB|rcsb pdb:5SZC|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5T1G|rcsb pdb:5T1I|rcsb pdb:5T8R|rcsb pdb:5TBN|rcsb pdb:5TDR|rcsb pdb:5TDW|rcsb pdb:5U2J|rcsb pdb:5V21|rcsb pdb:5V22|rcsb pdb:5VA6|rcsb pdb:5VAB|rcsb pdb:5VGE|rcsb pdb:5VNB|rcsb pdb:5NND|rcsb pdb:5WLE|rcsb pdb:5WVO|rcsb pdb:5WXG|rcsb pdb:5WXH|rcsb pdb:5WYI|rcsb pdb:5X60|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5XFQ|rcsb pdb:5XFR|rcsb pdb:5XNV|rcsb pdb:5XTZ|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Y20|rcsb pdb:5Y2F|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:6AXJ|rcsb pdb:6AZE|rcsb pdb:6BHD|rcsb pdb:6BHE|rcsb pdb:6BHG|rcsb pdb:6BHH|rcsb pdb:6BHI|rcsb pdb:6D07|rcsb pdb:6D08|rcsb pdb:6E83|rcsb pdb:6E86|rcsb pdb:5WFC|rcsb pdb:6F6D|rcsb pdb:6HTS|rcsb pdb:6IEU|rcsb pdb:6IIS|rcsb pdb:6IIT|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6LS6|rcsb pdb:6LSD|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MIL|rcsb pdb:6MIM|rcsb pdb:6MIN|rcsb pdb:6MIO|rcsb pdb:6MIQ|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6HKT|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2H|rcsb pdb:6V2K|rcsb pdb:6V3N|rcsb pdb:6V41|rcsb pdb:6V92|rcsb pdb:6VIL|rcsb pdb:6WAV|rcsb pdb:6WW4|rcsb pdb:6YIF|rcsb pdb:6YIH|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:6R92|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7KLR|rcsb pdb:7LYC|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|ensembl:ENSG00000197153(gene)|ensembl:ENSG00000197409(gene)|ensembl:ENSG00000273983(gene)|ensembl:ENSG00000274750(gene)|ensembl:ENSG00000275379(gene)|ensembl:ENSG00000275714(gene)|ensembl:ENSG00000277775(gene)|ensembl:ENSG00000278828(gene)|ensembl:ENSG00000286522(gene)|ensembl:ENSG00000287080(gene)|ensembl:ENST00000356476(transcript)|ensembl:ENST00000359303(transcript)|ensembl:ENST00000369163(transcript)|ensembl:ENST00000612966(transcript)|ensembl:ENST00000613854(transcript)|ensembl:ENST00000614378(transcript)|ensembl:ENST00000614911(transcript)|ensembl:ENST00000616365(transcript)|ensembl:ENST00000618052(transcript)|ensembl:ENST00000621411(transcript)|ensembl:ENST00000634733(transcript)|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-3247509|reactome:R-HSA-9710421|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060968"(obsolete regulation of gene silencing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|interpro:IPR009072(Histone-fold)|mint:P68431|rcsb pdb:1CS9|rcsb pdb:1CT6|rcsb pdb:1O9S|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|rcsb pdb:1Q3L|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|rcsb pdb:2B2T|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|rcsb pdb:2B2U|rcsb pdb:2B2V|rcsb pdb:2B2W|rcsb pdb:2C1J|rcsb pdb:2C1N|go:"GO:0016020"(membrane)|rcsb pdb:2CO0|rcsb pdb:2CV5|rcsb pdb:2FSA|rcsb pdb:2KWJ|rcsb pdb:2KWK|rcsb pdb:2L75|rcsb pdb:2LBM|rcsb pdb:2LGG|rcsb pdb:2M0O|reactome:R-HSA-983231|reactome:R-HSA-977225|rcsb pdb:2NDG|rcsb pdb:2OQ6|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2RI7|rcsb pdb:2RR4|rcsb pdb:2UXN|rcsb pdb:2V85|rcsb pdb:2V89|rcsb pdb:2VNF|rcsb pdb:2VPG|rcsb pdb:2X0L|rcsb pdb:3A1B|rcsb pdb:2NDF|rcsb pdb:3AFA|rcsb pdb:3AVR|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3B95|rcsb pdb:3FDT|rcsb pdb:3KMT|rcsb pdb:3KQI|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3MP1|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O37|rcsb pdb:3QJ6|rcsb pdb:3RIG|rcsb pdb:3RIY|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3U31|rcsb pdb:3U3D|rcsb pdb:3U4S|rcsb pdb:3U5N|rcsb pdb:3U5O|rcsb pdb:3AZK|rcsb pdb:3U5P|rcsb pdb:3UEE|rcsb pdb:3UEF|rcsb pdb:3UII|rcsb pdb:3UIK|rcsb pdb:3V43|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:3ZG6|rcsb pdb:3ZVY|rcsb pdb:4A0J|rcsb pdb:4A0N|rcsb pdb:4A7J|rcsb pdb:3UIG|rcsb pdb:4BD3|rcsb pdb:4C1Q|rcsb pdb:4F4U|rcsb pdb:4F56|rcsb pdb:4FWF|rcsb pdb:4HON|rcsb pdb:4I51|rcsb pdb:4L7X|rcsb pdb:4LK9|rcsb pdb:4LKA|rcsb pdb:4LLB|rcsb pdb:4LXL|rcsb pdb:4N4H|rcsb pdb:4QBQ|rcsb pdb:4QBR|refseq:NP_003520.1|refseq:NP_003521.2|refseq:NP_003522.1|refseq:NP_003523.1|refseq:NP_003524.1|refseq:NP_003525.1|refseq:NP_003526.1|refseq:NP_003527.1|refseq:NP_003528.1|refseq:NP_066298.1|dip:DIP-29371N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:ood0OohxZHuhsWZtO7U7GMc+LwM9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:Q71DI3 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-750650|uniprotkb:A2BDF6|uniprotkb:A6NFS4|uniprotkb:Q6B053|ensembl:ENSP00000333277|ensembl:ENSP00000358154|ensembl:ENSP00000385479 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:h32_human(display_long)|uniprotkb:H3C13(gene name)|psi-mi:H3C13(display_short)|uniprotkb:H3C14(gene name)|psi-mi:H3C14(display_short)|uniprotkb:H3C15(gene name)|psi-mi:H3C15(display_short)|uniprotkb:H3-clustered histone 13(gene name synonym)|uniprotkb:H3-clustered histone 14(gene name synonym)|uniprotkb:H3-clustered histone 15(gene name synonym)|uniprotkb:H3F2(gene name synonym)|uniprotkb:H3FM(gene name synonym)|uniprotkb:HIST2H3A(gene name synonym)|uniprotkb:HIST2H3C(gene name synonym)|uniprotkb:HIST2H3D(gene name synonym)|uniprotkb:Histone H3/m(gene name synonym)|uniprotkb:Histone H3/o(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) refseq:NP_001005464.1|refseq:NP_001116847.1|refseq:NP_066403.2|dip:DIP-48606N|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|rcsb pdb:7BU9|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214858|reactome:R-HSA-3247509|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-983231|rcsb pdb:7JZV|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|ensembl:ENSG00000183598(gene)|ensembl:ENSG00000203811(gene)|ensembl:ENSG00000203852(gene)|ensembl:ENST00000331491(transcript)|ensembl:ENST00000369158(transcript)|ensembl:ENST00000403683(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q71DI3|rcsb pdb:2IIJ|rcsb pdb:2X4W|rcsb pdb:2X4X|rcsb pdb:2X4Y|rcsb pdb:3AV1|rcsb pdb:3DB3|rcsb pdb:3MO8|rcsb pdb:3QO2|rcsb pdb:3R93|rcsb pdb:4MZF|rcsb pdb:4MZG|rcsb pdb:4MZH|rcsb pdb:4OUC|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B40|rcsb pdb:5BO0|rcsb pdb:5CIU|rcsb pdb:5VAC|rcsb pdb:6ACE|rcsb pdb:6FML|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6Y5E|rcsb pdb:7BQZ - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:Q9BQE3 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:Q5QNW6 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-6147754|uniprotkb:B4DLA9|uniprotkb:A8K0U9|ensembl:ENSP00000358164 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:h2b2f_human(display_long)|uniprotkb:H2BC18(gene name)|psi-mi:H2BC18(display_short)|uniprotkb:H2B-clustered histone 18(gene name synonym)|uniprotkb:HIST2H2BF(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) refseq:NP_001019770.1|refseq:NP_001154806.1|ensembl:ENSG00000203814(gene)|ensembl:ENST00000369167(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q5QNW6|rcsb pdb:6MUO|rcsb pdb:6MUP|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-5689880|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:Pr400UVIaD7O446lc9vZeStUKn09606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:P62807 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-354552|uniprotkb:Q4VB69|uniprotkb:P02278|uniprotkb:Q3B872|uniprotkb:Q93078|uniprotkb:Q93080|ensembl:ENSP00000321744|ensembl:ENSP00000348924|ensembl:ENSP00000366962|ensembl:ENSP00000380180|ensembl:ENSP00000445633|ensembl:ENSP00000483237|ensembl:ENSP00000489317 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:h2b1c_human(display_long)|uniprotkb:HIST1H2BG(gene name synonym)|uniprotkb:HIST1H2BI(gene name synonym)|uniprotkb:Histone H2B.1 A(gene name synonym)|uniprotkb:Histone H2B.a(gene name synonym)|uniprotkb:Histone H2B.g(gene name synonym)|uniprotkb:Histone H2B.h(gene name synonym)|uniprotkb:Histone H2B.k(gene name synonym)|uniprotkb:Histone H2B.l(gene name synonym)|uniprotkb:H2BC10(gene name)|psi-mi:H2BC10(display_short)|uniprotkb:H2BC4(gene name)|psi-mi:H2BC4(display_short)|uniprotkb:H2BC6(gene name)|psi-mi:H2BC6(display_short)|uniprotkb:H2BC7(gene name)|psi-mi:H2BC7(display_short)|uniprotkb:H2BC8(gene name)|psi-mi:H2BC8(display_short)|uniprotkb:H2BFA(gene name synonym)|uniprotkb:H2BFG(gene name synonym)|uniprotkb:H2BFH(gene name synonym)|uniprotkb:H2BFK(gene name synonym)|uniprotkb:H2BFL(gene name synonym)|uniprotkb:HIST1H2BC(gene name synonym)|uniprotkb:HIST1H2BE(gene name synonym)|uniprotkb:HIST1H2BF(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) refseq:NP_003509.1|refseq:NP_003513.1|refseq:NP_003514.2|refseq:NP_003516.1|refseq:NP_003517.2|refseq:NP_066407.1|rcsb pdb:7A08|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|rcsb pdb:6XJD|ensembl:ENSG00000180596(gene)|ensembl:ENSG00000273802(gene)|ensembl:ENSG00000274290(gene)|ensembl:ENSG00000277224(gene)|ensembl:ENSG00000278588(gene)|ensembl:ENST00000314332(transcript)|ensembl:ENST00000356530(transcript)|ensembl:ENST00000377733(transcript)|ensembl:ENST00000396984(transcript)|ensembl:ENST00000541790(transcript)|ensembl:ENST00000614097(transcript)|ensembl:ENST00000634910(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0042802"(identical protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P62807|rcsb pdb:5GT0|rcsb pdb:5KGF|rcsb pdb:6ACO|rcsb pdb:6C0W|rcsb pdb:6FML|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6X59|rcsb pdb:6X5A|dip:DIP-32890N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:00sapwbWn8dtUr7qoPsRPUlL35A9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:Q5VTE0 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-877809 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:ef1a3_human(display_long)|uniprotkb:EEF1A1P5(gene name)|psi-mi:EEF1A1P5(display_short)|uniprotkb:Eukaryotic elongation factor 1 A-like 3(gene name synonym)|uniprotkb:EEF1AL3(gene name synonym)|uniprotkb:Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR031157|reactome:R-HSA-156842|interpro:IPR027417 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:3t6tj3i+3CKTC1NsrHyBkeoRK789606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:P84243 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-120658|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q5VV55|uniprotkb:Q5VV56|uniprotkb:Q66I33|uniprotkb:Q9V3W4|ensembl:ENSP00000254810|ensembl:ENSP00000355778|ensembl:ENSP00000355780|ensembl:ENSP00000355781|ensembl:ENSP00000465813|ensembl:ENSP00000466020|ensembl:ENSP00000468714|ensembl:ENSP00000499275|ensembl:ENSP00000499385|ensembl:ENSP00000499800 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:h33_human(display_long)|uniprotkb:H3-3A(gene name)|psi-mi:H3-3A(display_short)|uniprotkb:H3-3B(gene name)|psi-mi:H3-3B(display_short)|uniprotkb:H3.3A(gene name synonym)|uniprotkb:H3.3B(gene name synonym)|uniprotkb:H3F3(gene name synonym)|uniprotkb:H3F3A(gene name synonym)|uniprotkb:H3F3B(gene name synonym)|uniprotkb:PP781(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) refseq:NP_002098.1|refseq:NP_005315.1|rcsb pdb:4H9N|rcsb pdb:3QL9|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:3QLA|rcsb pdb:3QLC|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4L58|rcsb pdb:4N4I|rcsb pdb:3WTP|rcsb pdb:4O62|rcsb pdb:4QQ4|rcsb pdb:4TMP|rcsb pdb:4GNE|rcsb pdb:4GNF|rcsb pdb:4U7T|rcsb pdb:4GNG|rcsb pdb:4W5A|rcsb pdb:4GU0|rcsb pdb:4GUR|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:4GUS|rcsb pdb:4GY5|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5JA4|rcsb pdb:5JJY|ensembl:ENSG00000132475(gene)|ensembl:ENSG00000163041(gene)|rcsb pdb:5JLB|rcsb pdb:5KDM|rcsb pdb:5X7X|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6HGT|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6J9J|rcsb pdb:6PZV|rcsb pdb:6QXZ|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6U04|rcsb pdb:7A08|reactome:R-HSA-427413|rcsb pdb:7CIZ|reactome:R-HSA-5250924|reactome:R-HSA-5334118|rcsb pdb:7CJ0|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-983231|rcsb pdb:7CWH|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-427359|reactome:R-HSA-427389|ensembl:ENST00000254810(transcript)|ensembl:ENST00000366813(transcript)|ensembl:ENST00000366815(transcript)|ensembl:ENST00000366816(transcript)|ensembl:ENST00000586607(transcript)|ensembl:ENST00000587560(transcript)|ensembl:ENST00000589599(transcript)|ensembl:ENST00000655399(transcript)|ensembl:ENST00000661429(transcript)|ensembl:ENST00000666609(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P84243|rcsb pdb:2L43|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3AV2|rcsb pdb:3JVK|rcsb pdb:3MUK|rcsb pdb:3MUL|dip:DIP-40046N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:cRqA5/IBNfIbbxAnbwLqzXip20I9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:Q99879 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-3893474|uniprotkb:Q6NWQ3|ensembl:ENSP00000477907 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:h2b1m_human(display_long)|uniprotkb:H2BC14(gene name)|psi-mi:H2BC14(display_short)|uniprotkb:H2BFE(gene name synonym)|uniprotkb:HIST1H2BM(gene name synonym)|uniprotkb:Histone H2B.e(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) refseq:NP_003512.1|ensembl:ENSG00000273703(gene)|ensembl:ENST00000621112(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-912446|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:ETy0Ge+X/+GWAlBGq+YpQLc+DoE9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:P05141 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:P20671 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-4407441|uniprotkb:A0PK91|uniprotkb:P57754|uniprotkb:Q6FGY6|ensembl:ENSP00000341094 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:h2a1d_human(display_long)|uniprotkb:H2AC7(gene name)|psi-mi:H2AC7(display_short)|uniprotkb:H2AFG(gene name synonym)|uniprotkb:HIST1H2AD(gene name synonym)|uniprotkb:Histone H2A.3(gene name synonym)|uniprotkb:Histone H2A/g(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) refseq:NP_066409.1|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000196866(gene)|ensembl:ENST00000341023(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:5GT3|rcsb pdb:6KBB|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:Geraq+dGw3pvAAhgzzXQnYxDOOw9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:Q99878 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-6147676|uniprotkb:Q5JXQ5|uniprotkb:A2RUU6|ensembl:ENSP00000328484 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:h2a1j_human(display_long)|uniprotkb:H2AC14(gene name)|psi-mi:H2AC14(display_short)|uniprotkb:H2AFE(gene name synonym)|uniprotkb:HIST1H2AJ(gene name synonym)|uniprotkb:Histone H2A/e(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) refseq:NP_066544.1|ensembl:ENSG00000276368(gene)|ensembl:ENST00000333151(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:tS29VG3PpglHaYbu0w5z7pGvYyI9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:Q99880 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-1237119|uniprotkb:Q52LW9|uniprotkb:B2R5A3|ensembl:ENSP00000366618 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:h2b1l_human(display_long)|uniprotkb:H2BC13(gene name)|psi-mi:H2BC13(display_short)|uniprotkb:H2BFC(gene name synonym)|uniprotkb:HIST1H2BL(gene name synonym)|uniprotkb:Histone H2B.c(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) refseq:NP_003510.1|dip:DIP-38154N|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|ensembl:ENSG00000185130(gene)|ensembl:ENST00000377401(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|interpro:IPR009072(Histone-fold)|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5250924|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:vVD3xoHavMKCopzEez7zarZBKFc9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:P68104 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:Q16777 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-5325566|ensembl:ENSP00000332194|uniprotkb:Q6DRA7|uniprotkb:Q8IUE5 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:h2a2c_human(display_long)|uniprotkb:H2AC20(gene name)|psi-mi:H2AC20(display_short)|uniprotkb:H2A-clustered histone 20(gene name synonym)|uniprotkb:H2AFQ(gene name synonym)|uniprotkb:HIST2H2AC(gene name synonym)|uniprotkb:Histone H2A-GL101(gene name synonym)|uniprotkb:Histone H2A/q(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-5689603|ensembl:ENSG00000184260(gene)|ensembl:ENST00000331380(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q16777|rcsb pdb:6Y5E|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|refseq:NP_003508.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:Wejrpp9wK3GvA4ahJDVyEH+cwlQ9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:Q16695 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-358900|uniprotkb:Q6FGU4|uniprotkb:B2R5K3|ensembl:ENSP00000355657|ensembl:ENSP00000494070 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:h31t_human(display_long)|uniprotkb:H3-4(gene name)|psi-mi:H3-4(display_short)|uniprotkb:H3/g(gene name synonym)|uniprotkb:H3FT(gene name synonym)|uniprotkb:HIST3H3(gene name synonym)|uniprotkb:Histone H3.4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) refseq:NP_003484.1|ensembl:ENSG00000168148(gene)|ensembl:ENSG00000285435(gene)|ensembl:ENST00000366696(transcript)|ensembl:ENST00000644869(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q16695|rcsb pdb:2V1D|rcsb pdb:2YBP|rcsb pdb:2YBS|rcsb pdb:3A6N|rcsb pdb:3T6R|rcsb pdb:4V2V|rcsb pdb:4V2W|rcsb pdb:6OIE|rcsb pdb:6WAT|rcsb pdb:6WAU|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-201722|reactome:R-HSA-2299718|reactome:R-HSA-2559586|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-9670095|dip:DIP-922N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:izXHIcNCPCDQ7yevMtqWxTRt1bA9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:P35268 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-354533|intact:EBI-1055963|uniprotkb:Q6IBD1|uniprotkb:B2R495|ensembl:ENSP00000346088 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:rl22_human(display_long)|uniprotkb:RPL22(gene name)|psi-mi:RPL22(display_short)|uniprotkb:Heparin-binding protein HBp15(gene name synonym)|uniprotkb:Epstein-Barr virus small RNA-associated protein(gene name synonym)|uniprotkb:EBER-associated protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL22(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) refseq:NP_000974.1|ensembl:ENSG00000116251(gene)|ensembl:ENST00000234875(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008201"(heparin binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0045182"(translation regulator activity)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099577"(regulation of translation at presynapse, modulating synaptic transmission)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002671(Ribosomal protein L22e)|interpro:IPR038526|mint:P35268|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|reactome:R-HSA-72706|rcsb pdb:6Z6L|rcsb pdb:6Z6M|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:0TVillnqDkHmdTwxIedAJCVAdzY9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:O60814 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-4409738|uniprotkb:A8K7P7|uniprotkb:Q2VPI7|ensembl:ENSP00000349430 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:h2b1k_human(display_long)|uniprotkb:H2BC12(gene name)|psi-mi:H2BC12(display_short)|uniprotkb:H2BFT(gene name synonym)|uniprotkb:HIRA-interacting protein 1(gene name synonym)|uniprotkb:HIRIP1(gene name synonym)|uniprotkb:HIST1H2BK(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) refseq:NP_542160.1|refseq:NP_001299582.1|dip:DIP-48935N|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000197903(gene)|ensembl:ENST00000356950(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:O60814|rcsb pdb:2CV5|rcsb pdb:6KE9|rcsb pdb:6L9H|rcsb pdb:6LE9|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6V92|rcsb pdb:6Y5D|rcsb pdb:7BWD|rcsb pdb:7DBP|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:aBHcFUkMIdiiZov716H7kxmHzj09606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:P57053 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-2880265|ensembl:ENSP00000481622|uniprotkb:A0AVF9|uniprotkb:Q5R2W0 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:h2bfs_human(display_long)|uniprotkb:H2BS1(gene name)|psi-mi:H2BS1(display_short)|uniprotkb:H2B.S histone 1(gene name synonym)|uniprotkb:H2BFS(gene name synonym)|uniprotkb:Histone H2B.s(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) ensembl:ENSG00000234289(gene)|ensembl:ENST00000599962(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0021762"(substantia nigra development)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-427359|refseq:XP_006723981.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:x8Ryb6Tm0nfhcmsoTX5h5ZRsN7g9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:Q99877 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-744423|uniprotkb:Q494S8|uniprotkb:Q96FB7|uniprotkb:B2R5L4|ensembl:ENSP00000446031|ensembl:ENSP00000483903 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:h2b1n_human(display_long)|uniprotkb:H2BC15(gene name)|psi-mi:H2BC15(display_short)|uniprotkb:H2BFD(gene name synonym)|uniprotkb:HIST1H2BN(gene name synonym)|uniprotkb:Histone H2B.d(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) refseq:NP_003511.1|ensembl:ENSG00000233822(gene)|ensembl:ENST00000449538(transcript)|ensembl:ENST00000612898(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:nGZETothwO57PuE11M5ogikaZkM9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:Q05639 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-354943|ensembl:ENSP00000217182|uniprotkb:P54266|uniprotkb:Q0VGC7|uniprotkb:B5BUF3|uniprotkb:E1P5J1 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:ef1a2_human(display_long)|uniprotkb:EEF1A2(gene name)|psi-mi:EEF1A2(display_short)|uniprotkb:EEF1AL(gene name synonym)|uniprotkb:STN(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-2(gene name synonym)|uniprotkb:Statin-S1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) ensembl:ENSG00000101210(gene)|ensembl:ENST00000217182(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0090218"(positive regulation of lipid kinase activity)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:Q05639|rcsb pdb:3C5J|reactome:R-HSA-156842|refseq:NP_001949.1|dip:DIP-40060N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:vFXfcSRokxKo5RW0tRE1qEK0NKw9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:O14654 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-356594|ensembl:ENSP00000505547 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:P07437 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:P04908 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:4Qno1mMYZB6FdNoojrzulWLVq849606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:Q93077 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-725259|uniprotkb:O00775|uniprotkb:O00776|uniprotkb:O00777|uniprotkb:O00778|uniprotkb:Q540R1|uniprotkb:B2R4F7|ensembl:ENSP00000321389|ensembl:ENSP00000367022|ensembl:ENSP00000473534 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:h2a1c_human(display_long)|uniprotkb:H2AC6(gene name)|psi-mi:H2AC6(display_short)|uniprotkb:H2A-clustered histone 6(gene name synonym)|uniprotkb:H2AFL(gene name synonym)|uniprotkb:HIST1H2AC(gene name synonym)|uniprotkb:Histone H2A/l(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) refseq:NP_003503.1|ensembl:ENSG00000180573(gene)|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENST00000314088(transcript)|ensembl:ENST00000377791(transcript)|ensembl:ENST00000602637(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|rcsb pdb:6C0W|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:7A08|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|interpro:IPR032458 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:m00IdooZksbNGKHSsaVvGFVpcko9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:P12236 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-356254|ensembl:ENSP00000370808|uniprotkb:Q96C49 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) ensembl:ENSG00000169100(gene)|ensembl:ENST00000381401(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|refseq:NP_001627.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:P62805 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:P58876 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-4409942|ensembl:ENSP00000289316|ensembl:ENSP00000367008 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:h2b1d_human(display_long)|uniprotkb:Histone H2B.b(gene name synonym)|uniprotkb:H2BC5(gene name)|psi-mi:H2BC5(display_short)|uniprotkb:H2B-clustered histone 5(gene name synonym)|uniprotkb:H2BFB(gene name synonym)|uniprotkb:HIRA-interacting protein 2(gene name synonym)|uniprotkb:HIRIP2(gene name synonym)|uniprotkb:HIST1H2BD(gene name synonym)|uniprotkb:Histone H2B.1 B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) refseq:NP_066407.1|refseq:NP_619790.1|ensembl:ENSG00000158373(gene)|ensembl:ENST00000289316(transcript)|ensembl:ENST00000377777(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P58876|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005634"(nucleus) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:07VBw5MCphdkMydMOPSjVqpGriI9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:Q96KK5 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-6147668|ensembl:ENSP00000366679 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:h2a1h_human(display_long)|uniprotkb:H2AC12(gene name)|psi-mi:H2AC12(display_short)|uniprotkb:H2A-clustered histone 12(gene name synonym)|uniprotkb:HIST1H2AH(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:Histone H2A/s(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) refseq:NP_542163.1|dip:DIP-61699N|ensembl:ENSG00000274997(gene)|ensembl:ENST00000377459(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:Oa322n+evy8Cu0E9cWTEdYwQPKM9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:Q6FI13 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-353620|uniprotkb:P20670|uniprotkb:B2R5F0|ensembl:ENSP00000358155|ensembl:ENSP00000475814 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:h2a2a_human(display_long)|uniprotkb:H2AC18(gene name)|psi-mi:H2AC18(display_short)|uniprotkb:H2AC19(gene name)|psi-mi:H2AC19(display_short)|uniprotkb:H2A-clustered histone 18(gene name synonym)|uniprotkb:H2A-clustered histone 19(gene name synonym)|uniprotkb:H2AFO(gene name synonym)|uniprotkb:HIST2H2AA(gene name synonym)|uniprotkb:HIST2H2AA3(gene name synonym)|uniprotkb:HIST2H2AA4(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/o(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) refseq:NP_001035807.1|refseq:NP_003507.1|ensembl:ENSG00000203812(gene)|ensembl:ENSG00000272196(gene)|ensembl:ENST00000369159(transcript)|ensembl:ENST00000607355(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6Y5D|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|dip:DIP-33167N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:PMuIm2XMN5q4wk+wYJ94mmnCe4w9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:Q93079 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-352469|uniprotkb:Q4VB74|uniprotkb:B2R541|ensembl:ENSP00000479169 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:h2b1h_human(display_long)|uniprotkb:H2BC9(gene name)|psi-mi:H2BC9(display_short)|uniprotkb:H2B-clustered histone 9(gene name synonym)|uniprotkb:H2BFJ(gene name synonym)|uniprotkb:HIST1H2BH(gene name synonym)|uniprotkb:Histone H2B.j(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) refseq:NP_003515.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|ensembl:ENSG00000275713(gene)|ensembl:ENST00000619466(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0097677"(STAT family protein binding)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:W+7KkrtV9xv7ELLxmJFnI4LQoME9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:Q9BTM1 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-4398590|uniprotkb:Q9NV63|ensembl:ENSP00000373730|ensembl:ENSP00000438553 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:h2aj_human(display_long)|uniprotkb:H2AJ(gene name)|psi-mi:H2AJ(display_short)|uniprotkb:H2AFJ(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) refseq:NP_808760.1|ensembl:ENSG00000246705(gene)|ensembl:ENST00000389078(transcript)|ensembl:ENST00000544848(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:4EDU|rcsb pdb:6K60|rcsb pdb:6KVD|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-8939236 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:g6br63FeM17yJRfQI3GnmoM0vbc9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:Q7L7L0 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-5325551|ensembl:ENSP00000355656|ensembl:ENSP00000493926|uniprotkb:B2R4S4 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:h2a3_human(display_long)|uniprotkb:H2AW(gene name)|psi-mi:H2AW(display_short)|uniprotkb:HIST3H2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) ensembl:ENSG00000181218(gene)|ensembl:ENSG00000284841(gene)|ensembl:ENST00000366695(transcript)|refseq:NP_254280.1|ensembl:ENST00000645741(transcript)|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-5689603|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q7L7L0|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000786"(nucleosome)|dip:DIP-48936N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:t0RdR1SmUtmwRjtCS3uTyLGqSUI9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:Q9UMR2 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-719232|uniprotkb:Q6FIB7|uniprotkb:Q6IAE0|uniprotkb:Q9H0U0|uniprotkb:B3KNE9|ensembl:ENSP00000288071|uniprotkb:Q96KE7|uniprotkb:B4DXS6|uniprotkb:E7EMK4 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:dd19b_human(display_long)|uniprotkb:DEAD box protein 19B(gene name synonym)|uniprotkb:DEAD box RNA helicase DEAD5(gene name synonym)|uniprotkb:DDX19B(gene name)|psi-mi:DDX19B(display_short)|uniprotkb:DBP5(gene name synonym)|uniprotkb:DDX19(gene name synonym)|uniprotkb:TDBP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) refseq:NP_001014449.1|refseq:NP_001014451.1|refseq:NP_009173.1|ensembl:ENSG00000157349(gene)|ensembl:ENST00000288071(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:3EWS|rcsb pdb:3FHC|rcsb pdb:3FHT|rcsb pdb:3FMO|rcsb pdb:3FMP|rcsb pdb:3G0H|rcsb pdb:6B4I|rcsb pdb:6B4J|rcsb pdb:6B4K|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0070062"(extracellular exosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:NP_001244102.1|refseq:NP_001244103.1|refseq:NP_001244101.1|dip:DIP-48486N|refseq:XP_006721190.1|refseq:XP_016878379.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:1UiDyTWXtMNt5s6Dw86KD1xY+0o9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:P0C0S8 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:Q13085 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-717681|intact:EBI-3962262|uniprotkb:B2ZZ90|uniprotkb:Q6KEV6|uniprotkb:Q6XDA8|uniprotkb:Q7Z2G8|uniprotkb:Q7Z561|uniprotkb:Q7Z563|uniprotkb:Q7Z564|uniprotkb:Q86WB2|uniprotkb:Q86WB3|uniprotkb:B2RP68|ensembl:ENSP00000478547|ensembl:ENSP00000483674 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:acaca_human(display_long)|uniprotkb:ACACA(gene name)|psi-mi:ACACA(display_short)|uniprotkb:ACAC(gene name synonym)|uniprotkb:ACC1(gene name synonym)|uniprotkb:ACCA(gene name synonym)|uniprotkb:Acetyl-Coenzyme A carboxylase alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) refseq:NP_942131.1|refseq:NP_942133.1|refseq:NP_942134.1|refseq:NP_942135.1|refseq:NP_942136.1|refseq:XP_016880044.1|refseq:XP_011523005.1|ensembl:ENSG00000275176(gene)|ensembl:ENSG00000278540(gene)|ensembl:ENST00000613687(transcript)|ensembl:ENST00000614428(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003989"(acetyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019538"(protein metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:2001295"(malonyl-CoA biosynthetic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013537(Acetyl-CoA carboxylase, central region)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR029045|interpro:IPR034733|mint:Q13085|rcsb pdb:2YL2|rcsb pdb:3COJ|rcsb pdb:4ASI|rcsb pdb:6G2D|rcsb pdb:6G2H|rcsb pdb:6G2I|reactome:R-HSA-163765|reactome:R-HSA-196780|reactome:R-HSA-200425|reactome:R-HSA-2426168|reactome:R-HSA-3371599|reactome:R-HSA-75105|dip:DIP-36122N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:P9d0QlkoP1zrBdF1WOrK68ueGng9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P15059 uniprotkb:Q9NUU7 intact:EBI-6151240|uniprotkb:Q76ZL0 intact:EBI-740301|uniprotkb:Q53FM0|uniprotkb:B2RPL0|uniprotkb:B4DRZ7|ensembl:ENSP00000306117 psi-mi:spi2_vaccw(display_long)|uniprotkb:B13R(orf name)|uniprotkb:VACWR195(locus name)|uniprotkb:SPI-2(gene name)|psi-mi:SPI-2(display_short) psi-mi:dd19a_human(display_long)|uniprotkb:DEAD box protein 19A(gene name synonym)|uniprotkb:DDX19-like protein(gene name synonym)|uniprotkb:DDX19A(gene name)|psi-mi:DDX19A(display_short)|uniprotkb:DDX19L(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158108|imex:IM-17331-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-HSA-5218900|interpro:IPR036186|reactome:R-HSA-5357905|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|refseq:YP_233077.1|interpro:IPR042178|interpro:IPR042185|interpro:IPR015557(Protease inhibitor I4, serpin B1)|reactome:R-HSA-9686347|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process) refseq:NP_060802.1|ensembl:ENSG00000168872(gene)|ensembl:ENST00000302243(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|refseq:NP_001307451.1|refseq:NP_001307454.1|refseq:NP_001307455.1|refseq:NP_001307456.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:qvvuZ5i5pl+VI+nb9rQjoTRbA1I10254 rogid:Uvjex/lODTGHjNguDqyaquwkNaw9606 intact-crc:50AABCE23DB94737|rigid:EksRVDXdE5Mivx4Zh2Gxsx5KWEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F5HF68 uniprotkb:Q92793 intact:EBI-6151357 intact:EBI-81215|ensembl:ENSP00000262367|uniprotkb:O00147|uniprotkb:Q16376|uniprotkb:D3DUC9|uniprotkb:Q4LE28 psi-mi:virf1_hhv8p(display_long)|uniprotkb:vIRF-1(gene name)|psi-mi:vIRF-1(display_short) psi-mi:cbp_human(display_long)|uniprotkb:CREBBP(gene name)|psi-mi:CREBBP(display_short)|uniprotkb:CBP(gene name synonym)|uniprotkb:Histone lysine acetyltransferase CREBBP(gene name synonym)|uniprotkb:Protein-lysine acetyltransferase CREBBP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:868565(hhv8p)|taxid:868565(Human herpesvirus 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158222|imex:IM-17331-50 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036388|interpro:IPR036390|rcsb pdb:4YSI|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|refseq:YP_001129411.1|rcsb pdb:4HLY|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0036472"(suppression by virus of host protein-protein interaction)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus) ensembl:ENSG00000005339(gene)|ensembl:ENST00000262367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006473"(protein acetylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0034212"(peptide N-acetyltransferase activity)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042592"(homeostatic process)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043426"(MRF binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1990258"(histone glutamine methylation)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|rcsb pdb:1WO7|rcsb pdb:1ZOQ|rcsb pdb:2D82|rcsb pdb:2KJE|rcsb pdb:2KWF|rcsb pdb:2L84|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|mint:Q92793|rcsb pdb:1JSP|rcsb pdb:1LIQ|rcsb pdb:1RDT|rcsb pdb:1WO3|rcsb pdb:1WO4|rcsb pdb:1WO5|rcsb pdb:1WO6|rcsb pdb:2L85|rcsb pdb:2LXT|rcsb pdb:2LXS|rcsb pdb:3DWY|rcsb pdb:2N1A|rcsb pdb:3P1C|rcsb pdb:3P1D|refseq:NP_001073315.1|refseq:NP_004371.2|rcsb pdb:3P1E|rcsb pdb:3P1F|rcsb pdb:2RNY|rcsb pdb:6AY3|rcsb pdb:6AY5|rcsb pdb:6DMK|rcsb pdb:6ES5|rcsb pdb:6ES6|rcsb pdb:6ES7|rcsb pdb:6SQM|rcsb pdb:6FQO|rcsb pdb:6SXX|rcsb pdb:6YIJ|rcsb pdb:6YIK|rcsb pdb:6YIL|rcsb pdb:6YIM|rcsb pdb:6FQT|rcsb pdb:7CO1|rcsb pdb:7JFL|rcsb pdb:7JFM|reactome:R-HSA-1234158|rcsb pdb:6FQU|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1912408|rcsb pdb:6FR0|rcsb pdb:6FRF|rcsb pdb:6M64|rcsb pdb:6QST|reactome:R-HSA-1989781|reactome:R-HSA-201722|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-2644606|rcsb pdb:6SQE|rcsb pdb:6SQF|reactome:R-HSA-2894862|reactome:R-HSA-3134973|reactome:R-HSA-3214847|reactome:R-HSA-3371568|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-5621575|reactome:R-HSA-6803204|reactome:R-HSA-8866907|reactome:R-HSA-8939246|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-9614657|rcsb pdb:3SVH|rcsb pdb:4A9K|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4NR4|rcsb pdb:4NR5|rcsb pdb:4NR6|rcsb pdb:4NR7|rcsb pdb:4NYV|rcsb pdb:4NYW|rcsb pdb:4NYX|rcsb pdb:4OUF|rcsb pdb:4TQN|rcsb pdb:4TS8|rcsb pdb:4WHU|rcsb pdb:4YK0|rcsb pdb:5CGP|rcsb pdb:5DBM|rcsb pdb:5EIC|rcsb pdb:5ENG|rcsb pdb:5EP7|rcsb pdb:5GH9|rcsb pdb:5H85|rcsb pdb:5I83|rcsb pdb:5I86|rcsb pdb:5I89|rcsb pdb:5I8B|rcsb pdb:5I8G|rcsb pdb:5J0D|rcsb pdb:5JEM|rcsb pdb:5KTU|rcsb pdb:5KTW|rcsb pdb:5KTX|rcsb pdb:5LPJ|rcsb pdb:5LPL|rcsb pdb:5MME|rcsb pdb:5MMG|rcsb pdb:5MPK|rcsb pdb:5MPN|rcsb pdb:5MPZ|rcsb pdb:5MQE|rcsb pdb:5MQG|rcsb pdb:5MQK|rcsb pdb:5NLK|rcsb pdb:5NRW|rcsb pdb:5NU3|rcsb pdb:5OWK|rcsb pdb:5SVH|rcsb pdb:5TB6|rcsb pdb:5W0E|rcsb pdb:5W0F|rcsb pdb:5W0L|rcsb pdb:5W0Q|rcsb pdb:5XXH|rcsb pdb:6ALB|rcsb pdb:6ALC|rcsb pdb:6AXQ|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-9617629|dip:DIP-952N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:GR1vQ73Rww0U0PV79AOq+y5GMVs868565 rogid:WWX7TFIpcDwoR5f5Sm1eQ6nma1E9606 intact-crc:723F93865C3E1055|rigid:6J3ZTYEMxXMplJyOBb1Iq13OXK4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F5HF68 uniprotkb:Q09472 intact:EBI-6151357 intact:EBI-447295|intact:EBI-3908041|uniprotkb:B1AKC2|intact:EBI-28987257|ensembl:ENSP00000263253 psi-mi:virf1_hhv8p(display_long)|uniprotkb:vIRF-1(gene name)|psi-mi:vIRF-1(display_short) psi-mi:ep300_human(display_long)|uniprotkb:Histone butyryltransferase p300(gene name synonym)|uniprotkb:Histone crotonyltransferase p300(gene name synonym)|uniprotkb:Protein propionyltransferase p300(gene name synonym)|uniprotkb:EP300(gene name)|psi-mi:EP300(display_short)|uniprotkb:P300(gene name synonym)|uniprotkb:E1A-associated protein p300(gene name synonym)|uniprotkb:Protein 2-hydroxyisobutyryltransferase p300(gene name synonym)|uniprotkb:Protein lactyltransferas p300(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:868565(hhv8p)|taxid:868565(Human herpesvirus 8) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158222|imex:IM-17331-50 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036388|interpro:IPR036390|rcsb pdb:4YSI|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|refseq:YP_001129411.1|rcsb pdb:4HLY|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0036472"(suppression by virus of host protein-protein interaction)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|go:"GO:0039650"(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0042025"(host cell nucleus) refseq:NP_001420.2|ensembl:ENSP00000263253|dip:DIP-257N|go:"GO:0140068"(histone crotonyltransferase activity)|go:"GO:0140069"(histone butyryltransferase activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1905636"(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|interpro:IPR000197(Zinc finger, TAZ-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001487(Bromodomain)|interpro:IPR003101(Coactivator CBP, KIX)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010303(Protein of unknown function DUF902, CREBbp)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013178(H3K56 histone acetylation protein, RTT109)|interpro:IPR014744(Nuclear receptor coactivator, CREB-bp-like, interlocking)|interpro:IPR018359|interpro:IPR031162|interpro:IPR035898|interpro:IPR036427|interpro:IPR036529|interpro:IPR037073|interpro:IPR038547|interpro:IPR043145|mint:Q09472|rcsb pdb:1L3E|rcsb pdb:1P4Q|rcsb pdb:2K8F|rcsb pdb:2MH0|rcsb pdb:2MZD|rcsb pdb:3BIY|rcsb pdb:3I3J|rcsb pdb:3IO2|go:"GO:0140067"(peptidyl-lysine butyrylation)|rcsb pdb:3P57|rcsb pdb:3T92|rcsb pdb:4PZR|rcsb pdb:4PZS|rcsb pdb:4PZT|rcsb pdb:5BT3|rcsb pdb:5KJ2|rcsb pdb:5LKT|rcsb pdb:5LKU|rcsb pdb:5LKX|rcsb pdb:5LKZ|rcsb pdb:5LPK|rcsb pdb:5LPM|rcsb pdb:5NU5|rcsb pdb:5XZC|rcsb pdb:6DS6|rcsb pdb:6FGN|rcsb pdb:6FGS|rcsb pdb:6GYR|rcsb pdb:6GYT|rcsb pdb:6K4N|rcsb pdb:6PF1|rcsb pdb:6PGU|rcsb pdb:6V8B|rcsb pdb:6V8K|rcsb pdb:6V8N|rcsb pdb:6V90|rcsb pdb:7LJE|reactome:R-HSA-1234158|reactome:R-HSA-1368082|reactome:R-HSA-156711|reactome:R-HSA-1912408|reactome:R-HSA-1989781|reactome:R-HSA-201722|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2197563|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3134973|reactome:R-HSA-3214847|reactome:R-HSA-3371568|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-5250924|reactome:R-HSA-5617472|reactome:R-HSA-5621575|reactome:R-HSA-5689901|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-6804758|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-8866907|reactome:R-HSA-8936459|reactome:R-HSA-8939243|reactome:R-HSA-8941856|reactome:R-HSA-8941858|reactome:R-HSA-8951936|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9031628|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-9614657|reactome:R-HSA-9616222|reactome:R-HSA-9617629|reactome:R-HSA-9707616|rcsb pdb:4BHW|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENSG00000100393(gene)|ensembl:ENST00000263253(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001756"(somitogenesis)|go:"GO:0001966"(thigmotaxis)|go:"GO:0002039"(p53 binding)|go:"GO:0002209"(behavioral defense response)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007611"(learning or memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0030324"(lung development)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034212"(peptide N-acetyltransferase activity)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006473"(protein acetylation)|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0006915"(apoptotic process)|go:"GO:0036268"(swimming)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043627"(response to estrogen)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043969"(histone H2B acetylation)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0061920"(protein propionyltransferase activity)|go:"GO:0061921"(peptidyl-lysine propionylation)|go:"GO:0090043"(regulation of tubulin deacetylation)|go:"GO:0097043"(histone H3-K56 acetylation)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0106226"(peptide 2-hydroxyisobutyryltransferase activity)|go:"GO:0120301"(histone lactyltransferase activity)|go:"GO:0140065"(peptide butyryltransferase activity)|go:"GO:0140066"(peptidyl-lysine crotonylation)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:GR1vQ73Rww0U0PV79AOq+y5GMVs868565 rogid:7XzMU6kWdFN0GiLox7RamD9pZeM9606 intact-crc:723F93865C3E1055|rigid:6J3ZTYEMxXMplJyOBb1Iq13OXK4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P29991 uniprotkb:P12036 intact:EBI-6151376 intact:EBI-2880271|uniprotkb:Q9UQ14|uniprotkb:Q9UJS7|uniprotkb:Q96HF8|uniprotkb:B4DYY4|ensembl:ENSP00000311997 psi-mi:polg_den27(display_long) psi-mi:nfh_human(display_long)|uniprotkb:NEFH(gene name)|psi-mi:NEFH(display_short)|uniprotkb:KIAA0845(gene name synonym)|uniprotkb:NFH(gene name synonym)|uniprotkb:200 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament triplet H protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:31635(den27)|taxid:31635("Dengue virus type 2 (strain 16681-PDK53)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158234|imex:IM-17331-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036253|interpro:IPR037172|interpro:IPR027287|interpro:IPR029063|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|rcsb pdb:2R29|rcsb pdb:3EVG|interpro:IPR026470|interpro:IPR026490|interpro:IPR027417|interpro:IPR038688|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|rcsb pdb:6FLA|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039574"(suppression by virus of host JAK-STAT cascade via inhibition of host TYK2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity) refseq:NP_066554.2|ensembl:ENSG00000100285(gene)|ensembl:ENST00000310624(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005883"(neurofilament)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0061564"(axon development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR010790(Protein of unknown function DUF1388)|interpro:IPR018039|interpro:IPR033183|interpro:IPR039008|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:LQZTizAYIpZIFN0gWg//aJ3kTt431635 rogid:TXMrn6SWBHIYQY1loZfVvMo9PtU9606 intact-crc:E08F0DA79738D2C3|rigid:Az+93lP/NZeF4wAUfX6rP9tfoWA false sufficient binding region:2492-3391|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P29991 uniprotkb:P52630 intact:EBI-6151376 intact:EBI-1546963|uniprotkb:Q16430|uniprotkb:Q16431|uniprotkb:Q9UDL4|intact:EBI-10989287|uniprotkb:B4DLC7|uniprotkb:G3V2M6|ensembl:ENSP00000315768 psi-mi:polg_den27(display_long) psi-mi:stat2_human(display_long)|uniprotkb:p113(gene name synonym)|uniprotkb:STAT2(gene name)|psi-mi:STAT2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:31635(den27)|taxid:31635("Dengue virus type 2 (strain 16681-PDK53)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158234|imex:IM-17331-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036253|interpro:IPR037172|interpro:IPR027287|interpro:IPR029063|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|rcsb pdb:2R29|rcsb pdb:3EVG|interpro:IPR026470|interpro:IPR026490|interpro:IPR027417|interpro:IPR038688|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|rcsb pdb:6FLA|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039574"(suppression by virus of host JAK-STAT cascade via inhibition of host TYK2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity) refseq:NP_005410.1|refseq:NP_938146.1|dip:DIP-38511N|ensembl:ENSG00000170581(gene)|ensembl:ENST00000314128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0090140"(regulation of mitochondrial fission)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022756|interpro:IPR035854|interpro:IPR036535|interpro:IPR036860|mint:P52630|rcsb pdb:2KA4|rcsb pdb:6UX2|rcsb pdb:6WCZ|reactome:R-HSA-8854691|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9679191 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:LQZTizAYIpZIFN0gWg//aJ3kTt431635 rogid:uA0lxm5vmrLClQRP7NItd0/u4Ko9606 intact-crc:E08F0DA79738D2C3|rigid:Az+93lP/NZeF4wAUfX6rP9tfoWA false sufficient binding region:2492-3391|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P29991 uniprotkb:P34931 intact:EBI-6151376 intact:EBI-354912|uniprotkb:O75634|uniprotkb:Q2HXR3|uniprotkb:Q8NE72|uniprotkb:A6NNB0|uniprotkb:Q96QC9|uniprotkb:Q9UQM1|uniprotkb:B0UXW8|ensembl:ENSP00000364805|ensembl:ENSP00000372881|ensembl:ENSP00000396486|ensembl:ENSP00000408347 psi-mi:polg_den27(display_long) psi-mi:hs71l_human(display_long)|uniprotkb:HSPA1L(gene name)|psi-mi:HSPA1L(display_short)|uniprotkb:Heat shock 70 kDa protein 1-Hom(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:31635(den27)|taxid:31635("Dengue virus type 2 (strain 16681-PDK53)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158234|imex:IM-17331-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036253|interpro:IPR037172|interpro:IPR027287|interpro:IPR029063|interpro:IPR000069(Flavivirus envelope glycoprotein M)|interpro:IPR000208(RNA-directed RNA polymerase, flaviviral)|interpro:IPR000336(Flaviviral glycoprotein E, immunoglobulin-like)|interpro:IPR000404(Flavivirus non-structural protein NS4A)|interpro:IPR000487(Flavivirus non-structural protein NS2B)|interpro:IPR000752(Flavivirus non-structural protein NS2A)|interpro:IPR001122(Flavivirus capsid protein C)|interpro:IPR001157(Flavivirus non-structural protein NS1)|interpro:IPR001528(Flavivirus non-structural protein NS4B)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001850("Peptidase S7, flavivirus helicase (NS3)")|interpro:IPR002535(Flavivirus polyprotein propeptide)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR011998(Viral glycoprotein E, central and dimerisation)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014412(Genome polyprotein, Flavivirus type)|interpro:IPR014756(Immunoglobulin E-set)|rcsb pdb:2R29|rcsb pdb:3EVG|interpro:IPR026470|interpro:IPR026490|interpro:IPR027417|interpro:IPR038688|interpro:IPR013755(Flaviviral glycoprotein E, central domain, region 1)|interpro:IPR013756(Flaviviral glycoprotein E, central domain, region 2)|interpro:IPR038055|interpro:IPR038302|interpro:IPR038345|rcsb pdb:6FLA|interpro:IPR043502|interpro:IPR043504|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004482"("mRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019028"(viral capsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0039574"(suppression by virus of host JAK-STAT cascade via inhibition of host TYK2 activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity) refseq:NP_005518.3|ensembl:ENSG00000204390(gene)|ensembl:ENSG00000206383(gene)|ensembl:ENSG00000234258(gene)|ensembl:ENSG00000236251(gene)|ensembl:ENST00000375654(transcript)|ensembl:ENST00000383390(transcript)|ensembl:ENST00000417601(transcript)|ensembl:ENST00000456772(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0072562"(blood microparticle)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P34931|rcsb pdb:3GDQ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:LQZTizAYIpZIFN0gWg//aJ3kTt431635 rogid:KS02DcMpD2sxSF36hUjKiSdYi4c9606 intact-crc:E08F0DA79738D2C3|rigid:Az+93lP/NZeF4wAUfX6rP9tfoWA false sufficient binding region:2492-3391|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35256 uniprotkb:Q13363 intact:EBI-6151406|uniprotkb:Q6T6T8|uniprotkb:Q38L40 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:vp24_mabvm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Marburg VP24(gene name synonym) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:33727(mabvm)|taxid:33727("Lake Victoria marburgvirus (strain Musoke-80)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158251|imex:IM-17331-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:YP_001531158.1|rcsb pdb:4OR8|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0055036"(virion membrane) refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:I4qfE0czrH1tKenXKUGUJ7gXdok33727 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 intact-crc:E2153EE629E0040E|rigid:x72PqFEHQzR0pG883gA+nKrX9cg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35256 uniprotkb:Q6S8J3 intact:EBI-6151406|uniprotkb:Q6T6T8|uniprotkb:Q38L40 intact:EBI-4289913|uniprotkb:Q6S8J4|uniprotkb:Q6S8J8|uniprotkb:Q6S8J5|ensembl:ENSP00000439189|ensembl:ENSP00000507284 psi-mi:vp24_mabvm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Marburg VP24(gene name synonym) psi-mi:potee_human(display_long)|uniprotkb:POTEE(gene name)|psi-mi:POTEE(display_short)|uniprotkb:A26C1A(gene name synonym)|uniprotkb:POTE2(gene name synonym)|uniprotkb:ANKRD26-like family C member 1A(gene name synonym)|uniprotkb:Prostate, ovary, testis-expressed protein on chromosome 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:33727(mabvm)|taxid:33727("Lake Victoria marburgvirus (strain Musoke-80)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158251|imex:IM-17331-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:YP_001531158.1|rcsb pdb:4OR8|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0055036"(virion membrane) ensembl:ENSG00000188219(gene)|ensembl:ENST00000356920(transcript)|ensembl:ENST00000683005(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005615"(extracellular space)|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR002110(Ankyrin)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020683|interpro:IPR036770|interpro:IPR039497|interpro:IPR043129|reactome:R-HSA-9035034|interpro:IPR020902|refseq:NP_001077007.1|refseq:XP_016859650.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:I4qfE0czrH1tKenXKUGUJ7gXdok33727 rogid:LMuv4bmAG2/uPyH5LR9q+ickvWI9606 intact-crc:E2153EE629E0040E|rigid:x72PqFEHQzR0pG883gA+nKrX9cg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35256 uniprotkb:Q16695 intact:EBI-6151406|uniprotkb:Q6T6T8|uniprotkb:Q38L40 intact:EBI-358900|uniprotkb:Q6FGU4|uniprotkb:B2R5K3|ensembl:ENSP00000355657|ensembl:ENSP00000494070 psi-mi:vp24_mabvm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Marburg VP24(gene name synonym) psi-mi:h31t_human(display_long)|uniprotkb:H3-4(gene name)|psi-mi:H3-4(display_short)|uniprotkb:H3/g(gene name synonym)|uniprotkb:H3FT(gene name synonym)|uniprotkb:HIST3H3(gene name synonym)|uniprotkb:Histone H3.4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:33727(mabvm)|taxid:33727("Lake Victoria marburgvirus (strain Musoke-80)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158251|imex:IM-17331-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:YP_001531158.1|rcsb pdb:4OR8|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0055036"(virion membrane) refseq:NP_003484.1|ensembl:ENSG00000168148(gene)|ensembl:ENSG00000285435(gene)|ensembl:ENST00000366696(transcript)|ensembl:ENST00000644869(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q16695|rcsb pdb:2V1D|rcsb pdb:2YBP|rcsb pdb:2YBS|rcsb pdb:3A6N|rcsb pdb:3T6R|rcsb pdb:4V2V|rcsb pdb:4V2W|rcsb pdb:6OIE|rcsb pdb:6WAT|rcsb pdb:6WAU|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-201722|reactome:R-HSA-2299718|reactome:R-HSA-2559586|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-9670095|dip:DIP-922N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:I4qfE0czrH1tKenXKUGUJ7gXdok33727 rogid:izXHIcNCPCDQ7yevMtqWxTRt1bA9606 intact-crc:E2153EE629E0040E|rigid:x72PqFEHQzR0pG883gA+nKrX9cg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35256 uniprotkb:Q05639 intact:EBI-6151406|uniprotkb:Q6T6T8|uniprotkb:Q38L40 intact:EBI-354943|ensembl:ENSP00000217182|uniprotkb:P54266|uniprotkb:Q0VGC7|uniprotkb:B5BUF3|uniprotkb:E1P5J1 psi-mi:vp24_mabvm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Marburg VP24(gene name synonym) psi-mi:ef1a2_human(display_long)|uniprotkb:EEF1A2(gene name)|psi-mi:EEF1A2(display_short)|uniprotkb:EEF1AL(gene name synonym)|uniprotkb:STN(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-2(gene name synonym)|uniprotkb:Statin-S1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:33727(mabvm)|taxid:33727("Lake Victoria marburgvirus (strain Musoke-80)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158251|imex:IM-17331-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:YP_001531158.1|rcsb pdb:4OR8|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0055036"(virion membrane) ensembl:ENSG00000101210(gene)|ensembl:ENST00000217182(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0090218"(positive regulation of lipid kinase activity)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:Q05639|rcsb pdb:3C5J|reactome:R-HSA-156842|refseq:NP_001949.1|dip:DIP-40060N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:I4qfE0czrH1tKenXKUGUJ7gXdok33727 rogid:vFXfcSRokxKo5RW0tRE1qEK0NKw9606 intact-crc:E2153EE629E0040E|rigid:x72PqFEHQzR0pG883gA+nKrX9cg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35256 uniprotkb:P0CG38 intact:EBI-6151406|uniprotkb:Q6T6T8|uniprotkb:Q38L40 intact:EBI-6151396|ensembl:ENSP00000392718 psi-mi:vp24_mabvm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Marburg VP24(gene name synonym) psi-mi:potei_human(display_long)|uniprotkb:POTEI(gene name)|psi-mi:POTEI(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:33727(mabvm)|taxid:33727("Lake Victoria marburgvirus (strain Musoke-80)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158251|imex:IM-17331-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:YP_001531158.1|rcsb pdb:4OR8|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0055036"(virion membrane) refseq:NP_001264335.1|ensembl:ENSG00000196834(gene)|ensembl:ENST00000451531(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005615"(extracellular space)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002110(Ankyrin)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020683|interpro:IPR020902|interpro:IPR036770|interpro:IPR039497|interpro:IPR043129 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:I4qfE0czrH1tKenXKUGUJ7gXdok33727 rogid:GwOezw/xl4lBr+foB8APX5SP8qc9606 intact-crc:E2153EE629E0040E|rigid:x72PqFEHQzR0pG883gA+nKrX9cg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35256 uniprotkb:Q71DI3 intact:EBI-6151406|uniprotkb:Q6T6T8|uniprotkb:Q38L40 intact:EBI-750650|uniprotkb:A2BDF6|uniprotkb:A6NFS4|uniprotkb:Q6B053|ensembl:ENSP00000333277|ensembl:ENSP00000358154|ensembl:ENSP00000385479 psi-mi:vp24_mabvm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Marburg VP24(gene name synonym) psi-mi:h32_human(display_long)|uniprotkb:H3C13(gene name)|psi-mi:H3C13(display_short)|uniprotkb:H3C14(gene name)|psi-mi:H3C14(display_short)|uniprotkb:H3C15(gene name)|psi-mi:H3C15(display_short)|uniprotkb:H3-clustered histone 13(gene name synonym)|uniprotkb:H3-clustered histone 14(gene name synonym)|uniprotkb:H3-clustered histone 15(gene name synonym)|uniprotkb:H3F2(gene name synonym)|uniprotkb:H3FM(gene name synonym)|uniprotkb:HIST2H3A(gene name synonym)|uniprotkb:HIST2H3C(gene name synonym)|uniprotkb:HIST2H3D(gene name synonym)|uniprotkb:Histone H3/m(gene name synonym)|uniprotkb:Histone H3/o(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:33727(mabvm)|taxid:33727("Lake Victoria marburgvirus (strain Musoke-80)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158251|imex:IM-17331-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:YP_001531158.1|rcsb pdb:4OR8|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0055036"(virion membrane) refseq:NP_001005464.1|refseq:NP_001116847.1|refseq:NP_066403.2|dip:DIP-48606N|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|rcsb pdb:7BU9|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214858|reactome:R-HSA-3247509|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-983231|rcsb pdb:7JZV|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|ensembl:ENSG00000183598(gene)|ensembl:ENSG00000203811(gene)|ensembl:ENSG00000203852(gene)|ensembl:ENST00000331491(transcript)|ensembl:ENST00000369158(transcript)|ensembl:ENST00000403683(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q71DI3|rcsb pdb:2IIJ|rcsb pdb:2X4W|rcsb pdb:2X4X|rcsb pdb:2X4Y|rcsb pdb:3AV1|rcsb pdb:3DB3|rcsb pdb:3MO8|rcsb pdb:3QO2|rcsb pdb:3R93|rcsb pdb:4MZF|rcsb pdb:4MZG|rcsb pdb:4MZH|rcsb pdb:4OUC|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B40|rcsb pdb:5BO0|rcsb pdb:5CIU|rcsb pdb:5VAC|rcsb pdb:6ACE|rcsb pdb:6FML|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6Y5E|rcsb pdb:7BQZ - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:I4qfE0czrH1tKenXKUGUJ7gXdok33727 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o9606 intact-crc:E2153EE629E0040E|rigid:x72PqFEHQzR0pG883gA+nKrX9cg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35256 uniprotkb:A5A3E0 intact:EBI-6151406|uniprotkb:Q6T6T8|uniprotkb:Q38L40 intact:EBI-6150673|uniprotkb:A6NC34|ensembl:ENSP00000386786 psi-mi:vp24_mabvm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Marburg VP24(gene name synonym) psi-mi:potef_human(display_long)|uniprotkb:POTEF(gene name)|psi-mi:POTEF(display_short)|uniprotkb:A26C1B(gene name synonym)|uniprotkb:ANKRD26-like family C member 1B(gene name synonym)|uniprotkb:Chimeric POTE-actin protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:33727(mabvm)|taxid:33727("Lake Victoria marburgvirus (strain Musoke-80)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158251|imex:IM-17331-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:YP_001531158.1|rcsb pdb:4OR8|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0055036"(virion membrane) refseq:NP_001093241.1|ensembl:ENSG00000196604(gene)|ensembl:ENST00000409914(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005615"(extracellular space)|go:"GO:0005938"(cell cortex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR002110(Ankyrin)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020683|interpro:IPR020902|interpro:IPR036770|interpro:IPR039497|interpro:IPR043129 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:I4qfE0czrH1tKenXKUGUJ7gXdok33727 rogid:alL+OQ/juWHafyF1GwIiLOPZZso9606 intact-crc:E2153EE629E0040E|rigid:x72PqFEHQzR0pG883gA+nKrX9cg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35256 uniprotkb:P62736 intact:EBI-6151406|uniprotkb:Q6T6T8|uniprotkb:Q38L40 intact:EBI-698810|uniprotkb:P03996|uniprotkb:P04108|uniprotkb:Q6FI19|uniprotkb:B2R8A4|ensembl:ENSP00000224784 psi-mi:vp24_mabvm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Marburg VP24(gene name synonym) psi-mi:acta_human(display_long)|uniprotkb:Alpha-actin-2(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 46 protein(gene name synonym)|uniprotkb:ACTA2(gene name)|psi-mi:ACTA2(display_short)|uniprotkb:ACTSA(gene name synonym)|uniprotkb:ACTVS(gene name synonym)|uniprotkb:GIG46(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:33727(mabvm)|taxid:33727("Lake Victoria marburgvirus (strain Musoke-80)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158251|imex:IM-17331-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:YP_001531158.1|rcsb pdb:4OR8|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0055036"(virion membrane) refseq:NP_001135417.1|refseq:NP_001604.1|refseq:NP_001307784.1|ensembl:ENSG00000107796(gene)|ensembl:ENST00000224784(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014829"(vascular associated smooth muscle contraction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072144"(glomerular mesangial cell development)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P62736|reactome:R-HSA-445355|reactome:R-HSA-9013695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:I4qfE0czrH1tKenXKUGUJ7gXdok33727 rogid:mRZGUdL/jBuj6nVHtxoasZuA7yA9606 intact-crc:E2153EE629E0040E|rigid:x72PqFEHQzR0pG883gA+nKrX9cg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35256 uniprotkb:P07437 intact:EBI-6151406|uniprotkb:Q6T6T8|uniprotkb:Q38L40 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:vp24_mabvm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Marburg VP24(gene name synonym) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:33727(mabvm)|taxid:33727("Lake Victoria marburgvirus (strain Musoke-80)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158251|imex:IM-17331-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:YP_001531158.1|rcsb pdb:4OR8|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0055036"(virion membrane) refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:I4qfE0czrH1tKenXKUGUJ7gXdok33727 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:E2153EE629E0040E|rigid:x72PqFEHQzR0pG883gA+nKrX9cg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35256 uniprotkb:P56545 intact:EBI-6151406|uniprotkb:Q6T6T8|uniprotkb:Q38L40 intact:EBI-741533|uniprotkb:O43449|uniprotkb:Q5SQP7|uniprotkb:Q69YI3|uniprotkb:Q86SV0|uniprotkb:Q9H2T8|uniprotkb:A8K2X5|ensembl:ENSP00000338615|ensembl:ENSP00000410474|ensembl:ENSP00000434630|ensembl:ENSP00000436285|uniprotkb:D3DRF5|uniprotkb:Q8IY44|intact:EBI-11742664 psi-mi:vp24_mabvm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Marburg VP24(gene name synonym) psi-mi:ctbp2_human(display_long)|uniprotkb:CTBP2(gene name)|psi-mi:CTBP2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:33727(mabvm)|taxid:33727("Lake Victoria marburgvirus (strain Musoke-80)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158251|imex:IM-17331-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:YP_001531158.1|rcsb pdb:4OR8|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0055036"(virion membrane) refseq:NP_001077383.1|refseq:NP_001320.1|refseq:NP_073713.2|refseq:NP_001307943.1|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:P56545|rcsb pdb:2OME|rcsb pdb:4LCJ|rcsb pdb:6WKW|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-9662360|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|ensembl:ENSG00000175029(gene)|ensembl:ENST00000337195(transcript)|ensembl:ENST00000411419(transcript)|ensembl:ENST00000494626(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|ensembl:ENST00000531469(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|refseq:XP_011537653.1|refseq:XP_011537655.1|refseq:XP_011537656.1|refseq:XP_011537657.1|refseq:NP_001307941.1|refseq:NP_001307942.1|refseq:XP_005269618.1|refseq:XP_005269621.1|refseq:XP_005269624.1|refseq:XP_005269625.1|refseq:XP_005269626.1|refseq:XP_005269628.1|refseq:XP_005269629.1|refseq:NP_001277143.1|refseq:NP_001277144.1|refseq:XP_006717705.1|refseq:XP_016871245.1|refseq:XP_016871246.1|dip:DIP-42104N|refseq:XP_011537651.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:I4qfE0czrH1tKenXKUGUJ7gXdok33727 rogid:6sKiqjMRW/ViEvTbQJoaUjgvZtc9606 intact-crc:E2153EE629E0040E|rigid:x72PqFEHQzR0pG883gA+nKrX9cg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35256 uniprotkb:P68431 intact:EBI-6151406|uniprotkb:Q6T6T8|uniprotkb:Q38L40 intact:EBI-79722|ensembl:ENSP00000352252|ensembl:ENSP00000358160|ensembl:ENSP00000366999|ensembl:ENSP00000480826|ensembl:ENSP00000482271|ensembl:ENSP00000483283|ensembl:ENSP00000484095|ensembl:ENSP00000484638|ensembl:ENSP00000484658|ensembl:ENSP00000484841|ensembl:ENSP00000489282|intact:EBI-1560041|uniprotkb:A0PJT7|uniprotkb:P02295|uniprotkb:P02296|uniprotkb:P16106|uniprotkb:Q6ISV8|uniprotkb:Q6NWP8|uniprotkb:Q6NWP9|uniprotkb:Q6NXU4|uniprotkb:Q71DJ3|uniprotkb:Q93081|uniprotkb:A5PLR1 psi-mi:vp24_mabvm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Marburg VP24(gene name synonym) psi-mi:h31_human(display_long)|uniprotkb:H3FA(gene name synonym)|uniprotkb:H3FL(gene name synonym)|uniprotkb:H3FD(gene name synonym)|uniprotkb:H3FI(gene name synonym)|uniprotkb:H3FH(gene name synonym)|uniprotkb:H3FK(gene name synonym)|uniprotkb:H3FF(gene name synonym)|uniprotkb:H3FJ(gene name synonym)|uniprotkb:H3FB(gene name synonym)|uniprotkb:Histone H3/a(gene name synonym)|uniprotkb:Histone H3/b(gene name synonym)|uniprotkb:Histone H3/c(gene name synonym)|uniprotkb:Histone H3/d(gene name synonym)|uniprotkb:Histone H3/f(gene name synonym)|uniprotkb:Histone H3/h(gene name synonym)|uniprotkb:Histone H3/i(gene name synonym)|uniprotkb:Histone H3/j(gene name synonym)|uniprotkb:Histone H3/k(gene name synonym)|uniprotkb:Histone H3/l(gene name synonym)|uniprotkb:H3C1(gene name)|psi-mi:H3C1(display_short)|uniprotkb:HIST1H3A(gene name synonym)|uniprotkb:H3C2(gene name)|psi-mi:H3C2(display_short)|uniprotkb:HIST1H3B(gene name synonym)|uniprotkb:H3C3(gene name)|psi-mi:H3C3(display_short)|uniprotkb:H3FC HIST1H3C(gene name synonym)|uniprotkb:H3C4(gene name)|psi-mi:H3C4(display_short)|uniprotkb:HIST1H3D(gene name synonym)|uniprotkb:H3C6(gene name)|psi-mi:H3C6(display_short)|uniprotkb:HIST1H3E(gene name synonym)|uniprotkb:H3C7(gene name)|psi-mi:H3C7(display_short)|uniprotkb:HIST1H3F(gene name synonym)|uniprotkb:H3C8(gene name)|psi-mi:H3C8(display_short)|uniprotkb:HIST1H3G(gene name synonym)|uniprotkb:H3C10(gene name)|psi-mi:H3C10(display_short)|uniprotkb:HIST1H3H(gene name synonym)|uniprotkb:H3C11(gene name)|psi-mi:H3C11(display_short)|uniprotkb:HIST1H3I(gene name synonym)|uniprotkb:H3C12(gene name)|psi-mi:H3C12(display_short)|uniprotkb:HIST1H3J(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:33727(mabvm)|taxid:33727("Lake Victoria marburgvirus (strain Musoke-80)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158251|imex:IM-17331-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:YP_001531158.1|rcsb pdb:4OR8|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0055036"(virion membrane) rcsb pdb:4TN7|rcsb pdb:4U68|rcsb pdb:4UP0|rcsb pdb:4UY4|rcsb pdb:4X3K|rcsb pdb:4Y6L|rcsb pdb:4YHP|rcsb pdb:4YHZ|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z0R|rcsb pdb:4Z2M|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:4QBS|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B31|rcsb pdb:5C11|rcsb pdb:5C13|rcsb pdb:5C3I|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5D6Y|rcsb pdb:5DAH|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5FFV|rcsb pdb:5GH9|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5HJB|rcsb pdb:5HJC|rcsb pdb:5HJD|rcsb pdb:5HYN|rcsb pdb:5IQL|rcsb pdb:5J3V|rcsb pdb:5J9S|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5B2J|rcsb pdb:5JRG|rcsb pdb:5KJH|rcsb pdb:5KJI|rcsb pdb:5KKL|rcsb pdb:5LUG|rcsb pdb:5M5G|rcsb pdb:5MR8|rcsb pdb:5NNC|rcsb pdb:5OY3|rcsb pdb:5SVX|rcsb pdb:5SVY|rcsb pdb:5SZB|rcsb pdb:5SZC|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5T1G|rcsb pdb:5T1I|rcsb pdb:5T8R|rcsb pdb:5TBN|rcsb pdb:5TDR|rcsb pdb:5TDW|rcsb pdb:5U2J|rcsb pdb:5V21|rcsb pdb:5V22|rcsb pdb:5VA6|rcsb pdb:5VAB|rcsb pdb:5VGE|rcsb pdb:5VNB|rcsb pdb:5NND|rcsb pdb:5WLE|rcsb pdb:5WVO|rcsb pdb:5WXG|rcsb pdb:5WXH|rcsb pdb:5WYI|rcsb pdb:5X60|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5XFQ|rcsb pdb:5XFR|rcsb pdb:5XNV|rcsb pdb:5XTZ|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Y20|rcsb pdb:5Y2F|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:6AXJ|rcsb pdb:6AZE|rcsb pdb:6BHD|rcsb pdb:6BHE|rcsb pdb:6BHG|rcsb pdb:6BHH|rcsb pdb:6BHI|rcsb pdb:6D07|rcsb pdb:6D08|rcsb pdb:6E83|rcsb pdb:6E86|rcsb pdb:5WFC|rcsb pdb:6F6D|rcsb pdb:6HTS|rcsb pdb:6IEU|rcsb pdb:6IIS|rcsb pdb:6IIT|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6LS6|rcsb pdb:6LSD|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MIL|rcsb pdb:6MIM|rcsb pdb:6MIN|rcsb pdb:6MIO|rcsb pdb:6MIQ|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6HKT|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2H|rcsb pdb:6V2K|rcsb pdb:6V3N|rcsb pdb:6V41|rcsb pdb:6V92|rcsb pdb:6VIL|rcsb pdb:6WAV|rcsb pdb:6WW4|rcsb pdb:6YIF|rcsb pdb:6YIH|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:6R92|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7KLR|rcsb pdb:7LYC|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|ensembl:ENSG00000197153(gene)|ensembl:ENSG00000197409(gene)|ensembl:ENSG00000273983(gene)|ensembl:ENSG00000274750(gene)|ensembl:ENSG00000275379(gene)|ensembl:ENSG00000275714(gene)|ensembl:ENSG00000277775(gene)|ensembl:ENSG00000278828(gene)|ensembl:ENSG00000286522(gene)|ensembl:ENSG00000287080(gene)|ensembl:ENST00000356476(transcript)|ensembl:ENST00000359303(transcript)|ensembl:ENST00000369163(transcript)|ensembl:ENST00000612966(transcript)|ensembl:ENST00000613854(transcript)|ensembl:ENST00000614378(transcript)|ensembl:ENST00000614911(transcript)|ensembl:ENST00000616365(transcript)|ensembl:ENST00000618052(transcript)|ensembl:ENST00000621411(transcript)|ensembl:ENST00000634733(transcript)|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-3247509|reactome:R-HSA-9710421|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060968"(obsolete regulation of gene silencing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|interpro:IPR009072(Histone-fold)|mint:P68431|rcsb pdb:1CS9|rcsb pdb:1CT6|rcsb pdb:1O9S|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|rcsb pdb:1Q3L|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|rcsb pdb:2B2T|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|rcsb pdb:2B2U|rcsb pdb:2B2V|rcsb pdb:2B2W|rcsb pdb:2C1J|rcsb pdb:2C1N|go:"GO:0016020"(membrane)|rcsb pdb:2CO0|rcsb pdb:2CV5|rcsb pdb:2FSA|rcsb pdb:2KWJ|rcsb pdb:2KWK|rcsb pdb:2L75|rcsb pdb:2LBM|rcsb pdb:2LGG|rcsb pdb:2M0O|reactome:R-HSA-983231|reactome:R-HSA-977225|rcsb pdb:2NDG|rcsb pdb:2OQ6|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2RI7|rcsb pdb:2RR4|rcsb pdb:2UXN|rcsb pdb:2V85|rcsb pdb:2V89|rcsb pdb:2VNF|rcsb pdb:2VPG|rcsb pdb:2X0L|rcsb pdb:3A1B|rcsb pdb:2NDF|rcsb pdb:3AFA|rcsb pdb:3AVR|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3B95|rcsb pdb:3FDT|rcsb pdb:3KMT|rcsb pdb:3KQI|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3MP1|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O37|rcsb pdb:3QJ6|rcsb pdb:3RIG|rcsb pdb:3RIY|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3U31|rcsb pdb:3U3D|rcsb pdb:3U4S|rcsb pdb:3U5N|rcsb pdb:3U5O|rcsb pdb:3AZK|rcsb pdb:3U5P|rcsb pdb:3UEE|rcsb pdb:3UEF|rcsb pdb:3UII|rcsb pdb:3UIK|rcsb pdb:3V43|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:3ZG6|rcsb pdb:3ZVY|rcsb pdb:4A0J|rcsb pdb:4A0N|rcsb pdb:4A7J|rcsb pdb:3UIG|rcsb pdb:4BD3|rcsb pdb:4C1Q|rcsb pdb:4F4U|rcsb pdb:4F56|rcsb pdb:4FWF|rcsb pdb:4HON|rcsb pdb:4I51|rcsb pdb:4L7X|rcsb pdb:4LK9|rcsb pdb:4LKA|rcsb pdb:4LLB|rcsb pdb:4LXL|rcsb pdb:4N4H|rcsb pdb:4QBQ|rcsb pdb:4QBR|refseq:NP_003520.1|refseq:NP_003521.2|refseq:NP_003522.1|refseq:NP_003523.1|refseq:NP_003524.1|refseq:NP_003525.1|refseq:NP_003526.1|refseq:NP_003527.1|refseq:NP_003528.1|refseq:NP_066298.1|dip:DIP-29371N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:I4qfE0czrH1tKenXKUGUJ7gXdok33727 rogid:ood0OohxZHuhsWZtO7U7GMc+LwM9606 intact-crc:E2153EE629E0040E|rigid:x72PqFEHQzR0pG883gA+nKrX9cg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35256 uniprotkb:Q5VTE0 intact:EBI-6151406|uniprotkb:Q6T6T8|uniprotkb:Q38L40 intact:EBI-877809 psi-mi:vp24_mabvm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Marburg VP24(gene name synonym) psi-mi:ef1a3_human(display_long)|uniprotkb:EEF1A1P5(gene name)|psi-mi:EEF1A1P5(display_short)|uniprotkb:Eukaryotic elongation factor 1 A-like 3(gene name synonym)|uniprotkb:EEF1AL3(gene name synonym)|uniprotkb:Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:33727(mabvm)|taxid:33727("Lake Victoria marburgvirus (strain Musoke-80)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158251|imex:IM-17331-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:YP_001531158.1|rcsb pdb:4OR8|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0055036"(virion membrane) go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR031157|reactome:R-HSA-156842|interpro:IPR027417 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:I4qfE0czrH1tKenXKUGUJ7gXdok33727 rogid:3t6tj3i+3CKTC1NsrHyBkeoRK789606 intact-crc:E2153EE629E0040E|rigid:x72PqFEHQzR0pG883gA+nKrX9cg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35256 uniprotkb:P84243 intact:EBI-6151406|uniprotkb:Q6T6T8|uniprotkb:Q38L40 intact:EBI-120658|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q5VV55|uniprotkb:Q5VV56|uniprotkb:Q66I33|uniprotkb:Q9V3W4|ensembl:ENSP00000254810|ensembl:ENSP00000355778|ensembl:ENSP00000355780|ensembl:ENSP00000355781|ensembl:ENSP00000465813|ensembl:ENSP00000466020|ensembl:ENSP00000468714|ensembl:ENSP00000499275|ensembl:ENSP00000499385|ensembl:ENSP00000499800 psi-mi:vp24_mabvm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Marburg VP24(gene name synonym) psi-mi:h33_human(display_long)|uniprotkb:H3-3A(gene name)|psi-mi:H3-3A(display_short)|uniprotkb:H3-3B(gene name)|psi-mi:H3-3B(display_short)|uniprotkb:H3.3A(gene name synonym)|uniprotkb:H3.3B(gene name synonym)|uniprotkb:H3F3(gene name synonym)|uniprotkb:H3F3A(gene name synonym)|uniprotkb:H3F3B(gene name synonym)|uniprotkb:PP781(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:33727(mabvm)|taxid:33727("Lake Victoria marburgvirus (strain Musoke-80)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158251|imex:IM-17331-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:YP_001531158.1|rcsb pdb:4OR8|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0055036"(virion membrane) refseq:NP_002098.1|refseq:NP_005315.1|rcsb pdb:4H9N|rcsb pdb:3QL9|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:3QLA|rcsb pdb:3QLC|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4L58|rcsb pdb:4N4I|rcsb pdb:3WTP|rcsb pdb:4O62|rcsb pdb:4QQ4|rcsb pdb:4TMP|rcsb pdb:4GNE|rcsb pdb:4GNF|rcsb pdb:4U7T|rcsb pdb:4GNG|rcsb pdb:4W5A|rcsb pdb:4GU0|rcsb pdb:4GUR|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:4GUS|rcsb pdb:4GY5|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5JA4|rcsb pdb:5JJY|ensembl:ENSG00000132475(gene)|ensembl:ENSG00000163041(gene)|rcsb pdb:5JLB|rcsb pdb:5KDM|rcsb pdb:5X7X|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6HGT|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6J9J|rcsb pdb:6PZV|rcsb pdb:6QXZ|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6U04|rcsb pdb:7A08|reactome:R-HSA-427413|rcsb pdb:7CIZ|reactome:R-HSA-5250924|reactome:R-HSA-5334118|rcsb pdb:7CJ0|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-983231|rcsb pdb:7CWH|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-427359|reactome:R-HSA-427389|ensembl:ENST00000254810(transcript)|ensembl:ENST00000366813(transcript)|ensembl:ENST00000366815(transcript)|ensembl:ENST00000366816(transcript)|ensembl:ENST00000586607(transcript)|ensembl:ENST00000587560(transcript)|ensembl:ENST00000589599(transcript)|ensembl:ENST00000655399(transcript)|ensembl:ENST00000661429(transcript)|ensembl:ENST00000666609(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P84243|rcsb pdb:2L43|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3AV2|rcsb pdb:3JVK|rcsb pdb:3MUK|rcsb pdb:3MUL|dip:DIP-40046N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:I4qfE0czrH1tKenXKUGUJ7gXdok33727 rogid:cRqA5/IBNfIbbxAnbwLqzXip20I9606 intact-crc:E2153EE629E0040E|rigid:x72PqFEHQzR0pG883gA+nKrX9cg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35256 uniprotkb:Q71U36 intact:EBI-6151406|uniprotkb:Q6T6T8|uniprotkb:Q38L40 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:vp24_mabvm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Marburg VP24(gene name synonym) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:33727(mabvm)|taxid:33727("Lake Victoria marburgvirus (strain Musoke-80)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158251|imex:IM-17331-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:YP_001531158.1|rcsb pdb:4OR8|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0055036"(virion membrane) refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:I4qfE0czrH1tKenXKUGUJ7gXdok33727 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 intact-crc:E2153EE629E0040E|rigid:x72PqFEHQzR0pG883gA+nKrX9cg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35256 uniprotkb:P68104 intact:EBI-6151406|uniprotkb:Q6T6T8|uniprotkb:Q38L40 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:vp24_mabvm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Marburg VP24(gene name synonym) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:33727(mabvm)|taxid:33727("Lake Victoria marburgvirus (strain Musoke-80)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158251|imex:IM-17331-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:YP_001531158.1|rcsb pdb:4OR8|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0055036"(virion membrane) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:I4qfE0czrH1tKenXKUGUJ7gXdok33727 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 intact-crc:E2153EE629E0040E|rigid:x72PqFEHQzR0pG883gA+nKrX9cg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35256 uniprotkb:P0CG39 intact:EBI-6151406|uniprotkb:Q6T6T8|uniprotkb:Q38L40 intact:EBI-6151401|ensembl:ENSP00000387176 psi-mi:vp24_mabvm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Marburg VP24(gene name synonym) psi-mi:potej_human(display_long)|uniprotkb:POTEJ(gene name)|psi-mi:POTEJ(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:33727(mabvm)|taxid:33727("Lake Victoria marburgvirus (strain Musoke-80)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158251|imex:IM-17331-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:YP_001531158.1|rcsb pdb:4OR8|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0055036"(virion membrane) refseq:NP_001264012.1|ensembl:ENSG00000222038(gene)|ensembl:ENST00000409602(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005615"(extracellular space)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002110(Ankyrin)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020683|interpro:IPR020902|interpro:IPR036770|interpro:IPR039497|interpro:IPR043129 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:I4qfE0czrH1tKenXKUGUJ7gXdok33727 rogid:FjaGG32SBA1jpjo0RFJpJ0gAyM89606 intact-crc:E2153EE629E0040E|rigid:x72PqFEHQzR0pG883gA+nKrX9cg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35256 uniprotkb:P62805 intact:EBI-6151406|uniprotkb:Q6T6T8|uniprotkb:Q38L40 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:vp24_mabvm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Marburg VP24(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:33727(mabvm)|taxid:33727("Lake Victoria marburgvirus (strain Musoke-80)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158251|imex:IM-17331-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:YP_001531158.1|rcsb pdb:4OR8|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0055036"(virion membrane) ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:I4qfE0czrH1tKenXKUGUJ7gXdok33727 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:E2153EE629E0040E|rigid:x72PqFEHQzR0pG883gA+nKrX9cg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35256 uniprotkb:Q9BQE3 intact:EBI-6151406|uniprotkb:Q6T6T8|uniprotkb:Q38L40 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:vp24_mabvm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Marburg VP24(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:33727(mabvm)|taxid:33727("Lake Victoria marburgvirus (strain Musoke-80)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158251|imex:IM-17331-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:YP_001531158.1|rcsb pdb:4OR8|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0055036"(virion membrane) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:I4qfE0czrH1tKenXKUGUJ7gXdok33727 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:E2153EE629E0040E|rigid:x72PqFEHQzR0pG883gA+nKrX9cg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35256 uniprotkb:Q00325 intact:EBI-6151406|uniprotkb:Q6T6T8|uniprotkb:Q38L40 intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34 psi-mi:vp24_mabvm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Marburg VP24(gene name synonym) psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:33727(mabvm)|taxid:33727("Lake Victoria marburgvirus (strain Musoke-80)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158251|imex:IM-17331-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:YP_001531158.1|rcsb pdb:4OR8|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0055036"(virion membrane) ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325 - - crc64:78714C85931B22D5 figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:I4qfE0czrH1tKenXKUGUJ7gXdok33727 rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606 intact-crc:E2153EE629E0040E|rigid:x72PqFEHQzR0pG883gA+nKrX9cg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35256 uniprotkb:Q6NXT2 intact:EBI-6151406|uniprotkb:Q6T6T8|uniprotkb:Q38L40 intact:EBI-2868501|uniprotkb:E9P281|ensembl:ENSP00000339835 psi-mi:vp24_mabvm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Marburg VP24(gene name synonym) psi-mi:h3c_human(display_long)|uniprotkb:H3-5(gene name)|psi-mi:H3-5(display_short)|uniprotkb:H3F3C(gene name synonym)|uniprotkb:Histone H3.5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:33727(mabvm)|taxid:33727("Lake Victoria marburgvirus (strain Musoke-80)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158251|imex:IM-17331-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:YP_001531158.1|rcsb pdb:4OR8|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0055036"(virion membrane) refseq:NP_001013721.2|go:"GO:0006997"(nucleus organization)|go:"GO:0007286"(spermatid development)|go:"GO:0007338"(single fertilization)|go:"GO:0007566"(embryo implantation)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0090230"(regulation of centromere complex assembly)|go:"GO:1902340"(negative regulation of chromosome condensation)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q6NXT2|rcsb pdb:2PUY|rcsb pdb:3KV4|rcsb pdb:4Z5T|rcsb pdb:5BWN|rcsb pdb:5BWO|rcsb pdb:5F6K|rcsb pdb:5I3L|rcsb pdb:6OI3|ensembl:ENSG00000188375(gene)|ensembl:ENST00000340398(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001740"(Barr body)|go:"GO:0005634"(nucleus) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:I4qfE0czrH1tKenXKUGUJ7gXdok33727 rogid:d8jgPwPl7fXRRpWh+ON9tiyrgnY9606 intact-crc:E2153EE629E0040E|rigid:x72PqFEHQzR0pG883gA+nKrX9cg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35256 uniprotkb:P63267 intact:EBI-6151406|uniprotkb:Q6T6T8|uniprotkb:Q38L40 intact:EBI-297795|uniprotkb:P12718|uniprotkb:Q504R1|uniprotkb:Q6FI22|ensembl:ENSP00000295137|ensembl:ENSP00000386857|uniprotkb:B2R7E7|uniprotkb:D6W5H8|uniprotkb:B4E315|uniprotkb:E9PG30 psi-mi:vp24_mabvm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Marburg VP24(gene name synonym) psi-mi:acth_human(display_long)|uniprotkb:ACTG2(gene name)|psi-mi:ACTG2(display_short)|uniprotkb:ACTA3(gene name synonym)|uniprotkb:ACTSG(gene name synonym)|uniprotkb:Smooth muscle gamma-actin(gene name synonym)|uniprotkb:Gamma-2-actin(gene name synonym)|uniprotkb:Alpha-actin-3(gene name synonym)|uniprotkb:ACTL3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:33727(mabvm)|taxid:33727("Lake Victoria marburgvirus (strain Musoke-80)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158251|imex:IM-17331-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:YP_001531158.1|rcsb pdb:4OR8|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0055036"(virion membrane) go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0032982"(myosin filament)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:6JAT|reactome:R-HSA-445355|go:"GO:0010628"(positive regulation of gene expression)|ensembl:ENST00000345517(transcript)|ensembl:ENST00000409624(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|ensembl:ENSG00000163017(gene)|refseq:NP_001186822.1|refseq:NP_001606.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:I4qfE0czrH1tKenXKUGUJ7gXdok33727 rogid:tp0JsXhrGsRl5i4Wg2dyaPGUPxA9606 intact-crc:E2153EE629E0040E|rigid:x72PqFEHQzR0pG883gA+nKrX9cg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35256 uniprotkb:P14314 intact:EBI-6151406|uniprotkb:Q6T6T8|uniprotkb:Q38L40 intact:EBI-716953|uniprotkb:Q96BU9|uniprotkb:Q96D06|uniprotkb:Q9P0W9|uniprotkb:A8K318|ensembl:ENSP00000465461 psi-mi:vp24_mabvm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Marburg VP24(gene name synonym) psi-mi:glu2b_human(display_long)|uniprotkb:Glucosidase II subunit beta(gene name synonym)|uniprotkb:Protein kinase C substrate 60.1 kDa protein heavy chain(gene name synonym)|uniprotkb:80K-H protein(gene name synonym)|uniprotkb:PRKCSH(gene name)|psi-mi:PRKCSH(display_short)|uniprotkb:G19P1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:33727(mabvm)|taxid:33727("Lake Victoria marburgvirus (strain Musoke-80)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158251|imex:IM-17331-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:YP_001531158.1|rcsb pdb:4OR8|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0055036"(virion membrane) refseq:NP_001001329.1|refseq:NP_002734.2|refseq:XP_011526433.1|refseq:XP_011526434.1|refseq:NP_001276031.1|ensembl:ENSG00000130175(gene)|ensembl:ENST00000589838(transcript)|go:"GO:0001889"(liver development)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006491"(N-glycan processing)|go:"GO:0017177"(glucosidase II complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028146|interpro:IPR036055|interpro:IPR036607|interpro:IPR039794|interpro:IPR044865|mint:P14314|reactome:R-HSA-381426|reactome:R-HSA-532668|reactome:R-HSA-879415|reactome:R-HSA-8957275|reactome:R-HSA-901042|reactome:R-HSA-9683686|reactome:R-HSA-9694548|refseq:XP_016882466.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:I4qfE0czrH1tKenXKUGUJ7gXdok33727 rogid:hs2AZthZKK6KVW8Blm1RuZVh1QM9606 intact-crc:E2153EE629E0040E|rigid:x72PqFEHQzR0pG883gA+nKrX9cg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35256 uniprotkb:Q14145 intact:EBI-6151406|uniprotkb:Q6T6T8|uniprotkb:Q38L40 intact:EBI-751001|uniprotkb:B3KPD5|uniprotkb:Q8WTX1|uniprotkb:Q6LEP0|uniprotkb:Q9BPY9|intact:EBI-28976014|ensembl:ENSP00000171111|ensembl:ENSP00000377245 psi-mi:vp24_mabvm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Marburg VP24(gene name synonym) psi-mi:keap1_human(display_long)|uniprotkb:Cytosolic inhibitor of Nrf2(gene name synonym)|uniprotkb:Kelch-like protein 19(gene name synonym)|uniprotkb:KEAP1(gene name)|psi-mi:KEAP1(display_short)|uniprotkb:INRF2(gene name synonym)|uniprotkb:KIAA0132(gene name synonym)|uniprotkb:KLHL19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:33727(mabvm)|taxid:33727("Lake Victoria marburgvirus (strain Musoke-80)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158251|imex:IM-17331-52 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:YP_001531158.1|rcsb pdb:4OR8|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0055036"(virion membrane) refseq:NP_036421.2|refseq:NP_987096.1|ensembl:ENSP00000171111|ensembl:ENSP00000377245|refseq:XP_011526754.1|refseq:XP_005260230.1|refseq:XP_005260231.1|dip:DIP-42134N|ensembl:ENSG00000079999(gene)|ensembl:ENST00000171111(transcript)|ensembl:ENST00000393623(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016234"(inclusion body)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030496"(midbody)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030563|mint:Q14145|rcsb pdb:1U6D|rcsb pdb:1ZGK|rcsb pdb:2FLU|rcsb pdb:3VNG|rcsb pdb:3VNH|rcsb pdb:3ZGC|rcsb pdb:3ZGD|rcsb pdb:4CXI|rcsb pdb:4CXJ|rcsb pdb:4CXT|rcsb pdb:4IFJ|rcsb pdb:4IFL|rcsb pdb:4IFN|rcsb pdb:4IN4|rcsb pdb:4IQK|rcsb pdb:4L7B|rcsb pdb:4L7C|rcsb pdb:4L7D|rcsb pdb:4N1B|rcsb pdb:4XMB|rcsb pdb:5DAD|rcsb pdb:5DAF|rcsb pdb:5F72|rcsb pdb:5GIT|rcsb pdb:5NLB|rcsb pdb:5WFL|rcsb pdb:5WFV|rcsb pdb:5WG1|rcsb pdb:5WHL|rcsb pdb:5WHO|rcsb pdb:5WIY|rcsb pdb:5X54|rcsb pdb:6FFM|rcsb pdb:6FMP|rcsb pdb:6FMQ|rcsb pdb:6HWS|rcsb pdb:6LRZ|rcsb pdb:6ROG|rcsb pdb:6SP1|rcsb pdb:6SP4|rcsb pdb:6T7V|rcsb pdb:6T7Z|rcsb pdb:6TG8|rcsb pdb:6TYM|rcsb pdb:6TYP|rcsb pdb:6UF0|rcsb pdb:6W66|rcsb pdb:6W67|rcsb pdb:6W68|rcsb pdb:6W69|rcsb pdb:6WCQ|rcsb pdb:6Z6A|rcsb pdb:7K28|rcsb pdb:7K29|rcsb pdb:7K2A|rcsb pdb:7K2B|rcsb pdb:7K2C|rcsb pdb:7K2D|rcsb pdb:7K2E|rcsb pdb:7K2F|rcsb pdb:7K2G|rcsb pdb:7K2H|rcsb pdb:7K2I|rcsb pdb:7K2J|rcsb pdb:7K2K|rcsb pdb:7K2L|rcsb pdb:7K2M|rcsb pdb:7K2N|rcsb pdb:7K2O|rcsb pdb:7K2P|rcsb pdb:7K2Q|rcsb pdb:7K2R|rcsb pdb:7K2S|reactome:R-HSA-5689880|reactome:R-HSA-8932339|reactome:R-HSA-8951664|reactome:R-HSA-983168|rcsb pdb:6V6Z - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:I4qfE0czrH1tKenXKUGUJ7gXdok33727 rogid:3y/KqnUK+5nIyjhOEfkkthmP1OA9606 intact-crc:E2153EE629E0040E|rigid:x72PqFEHQzR0pG883gA+nKrX9cg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q96A08 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-3951855|uniprotkb:B2R544|uniprotkb:Q6NZ98|uniprotkb:Q6NZA0|uniprotkb:Q6NZA1|ensembl:ENSP00000274764 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2b1a_human(display_long)|uniprotkb:HIST1H2BA(gene name synonym)|uniprotkb:Histone H2B, testis(gene name synonym)|uniprotkb:TSH2B(gene name synonym)|uniprotkb:H2BC1(gene name)|psi-mi:H2BC1(display_short)|uniprotkb:Testis-specific histone H2B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_733759.1|ensembl:ENSG00000146047(gene)|ensembl:ENST00000274764(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006954"(inflammatory response)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0031639"(plasminogen activation)|go:"GO:0035093"(spermatogenesis, exchange of chromosomal proteins)|go:"GO:0042393"(histone binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0071674"(mononuclear cell migration)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q96A08|rcsb pdb:3WKJ|rcsb pdb:5GSU|rcsb pdb:5GT3|rcsb pdb:6BIY|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-3214815 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:PwhaD8TxFmhrfRGI0MOJh0824uw9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q99879 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-3893474|uniprotkb:Q6NWQ3|ensembl:ENSP00000477907 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2b1m_human(display_long)|uniprotkb:H2BC14(gene name)|psi-mi:H2BC14(display_short)|uniprotkb:H2BFE(gene name synonym)|uniprotkb:HIST1H2BM(gene name synonym)|uniprotkb:Histone H2B.e(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_003512.1|ensembl:ENSG00000273703(gene)|ensembl:ENST00000621112(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-912446|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:ETy0Ge+X/+GWAlBGq+YpQLc+DoE9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P35637 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-400434|uniprotkb:Q9H4A8|ensembl:ENSP00000254108 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:fus_human(display_long)|uniprotkb:FUS(gene name)|psi-mi:FUS(display_short)|uniprotkb:TLS(gene name synonym)|uniprotkb:Oncogene FUS(gene name synonym)|uniprotkb:Oncogene TLS(gene name synonym)|uniprotkb:Translocated in liposarcoma protein(gene name synonym)|uniprotkb:POMp75(gene name synonym)|uniprotkb:75 kDa DNA-pairing protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_001164105.1|refseq:NP_004951.1|ensembl:ENSG00000089280(gene)|ensembl:ENST00000254108(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008380"(RNA splicing)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044327"(dendritic spine head)|go:"GO:0046872"(metal ion binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034459|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:P35637|rcsb pdb:2LA6|rcsb pdb:2LCW|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:5W3N|rcsb pdb:5XRR|rcsb pdb:5XSG|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:6BWZ|rcsb pdb:6BXV|rcsb pdb:6BZP|rcsb pdb:6G99|rcsb pdb:6GBM|rcsb pdb:6KJ1|rcsb pdb:6KJ2|rcsb pdb:6KJ3|rcsb pdb:6KJ4|rcsb pdb:6SNJ|rcsb pdb:6XFM|rcsb pdb:7CYL|reactome:R-HSA-72163|dip:DIP-29857N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:HUP4fGXQyJnm5CFTuwjTpiucZOc9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q96AX9 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-2130249|uniprotkb:B4DZ57|uniprotkb:J3KNZ7|uniprotkb:A2AGM5|uniprotkb:A2AGM6|uniprotkb:B3KV93|uniprotkb:B3KVF4|uniprotkb:Q7Z437|uniprotkb:Q8IY62|uniprotkb:Q8N786|uniprotkb:Q8N897|uniprotkb:Q8N8R2|uniprotkb:Q8N911|uniprotkb:Q8NB36|uniprotkb:Q8NCY1|uniprotkb:Q8NG59|uniprotkb:Q8NG60|uniprotkb:Q8NG61|uniprotkb:Q8NI59|uniprotkb:Q8WYN1|intact:EBI-11116994|uniprotkb:B3KXY1|uniprotkb:E9PGU1|uniprotkb:E9PHQ1|uniprotkb:F8WA73|intact:EBI-28979050 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:mib2_human(display_long)|uniprotkb:MIB2(gene name)|psi-mi:MIB2(display_short)|uniprotkb:SKD(gene name synonym)|uniprotkb:ZZANK1(gene name synonym)|uniprotkb:Mind bomb homolog 2(gene name synonym)|uniprotkb:Zinc finger ZZ type with ankyrin repeat domain protein 1(gene name synonym)|uniprotkb:Skeletrophin(gene name synonym)|uniprotkb:Novel zinc finger protein(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 002N(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MIB2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_001164157.1|refseq:NP_001164158.1|refseq:NP_001164159.1|refseq:NP_001164160.1|refseq:NP_543151.2|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR010606(Mib-herc2)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR036770|ensembl:ENST00000378712|ensembl:ENSP00000367984|ensembl:ENSG00000197530|reactome:R-HSA-983168|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-9013507|interpro:IPR037252|interpro:IPR040847|interpro:IPR042056|interpro:IPR043145|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003779"(actin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0061630"(ubiquitin protein ligase activity) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:5ExYcfCt7m+bIeZiCCZ0jk0jHOc9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P33778 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-357986|uniprotkb:Q4KN36|ensembl:ENSP00000482674 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2b1b_human(display_long)|uniprotkb:H2BC3(gene name)|psi-mi:H2BC3(display_short)|uniprotkb:H2B-clustered histone 3(gene name synonym)|uniprotkb:H2BFF(gene name synonym)|uniprotkb:HIST1H2BB(gene name synonym)|uniprotkb:Histone H2B.1(gene name synonym)|uniprotkb:Histone H2B.f(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_066406.1|dip:DIP-47505N|ensembl:ENSG00000276410(gene)|ensembl:ENST00000615966(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P33778|rcsb pdb:3X1S|rcsb pdb:3X1U|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:l15lrchv4onuihbdZ+yWJQd35Ss9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q99878 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-6147676|uniprotkb:Q5JXQ5|uniprotkb:A2RUU6|ensembl:ENSP00000328484 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2a1j_human(display_long)|uniprotkb:H2AC14(gene name)|psi-mi:H2AC14(display_short)|uniprotkb:H2AFE(gene name synonym)|uniprotkb:HIST1H2AJ(gene name synonym)|uniprotkb:Histone H2A/e(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_066544.1|ensembl:ENSG00000276368(gene)|ensembl:ENST00000333151(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:tS29VG3PpglHaYbu0w5z7pGvYyI9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q93079 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-352469|uniprotkb:Q4VB74|uniprotkb:B2R541|ensembl:ENSP00000479169 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2b1h_human(display_long)|uniprotkb:H2BC9(gene name)|psi-mi:H2BC9(display_short)|uniprotkb:H2B-clustered histone 9(gene name synonym)|uniprotkb:H2BFJ(gene name synonym)|uniprotkb:HIST1H2BH(gene name synonym)|uniprotkb:Histone H2B.j(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_003515.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|ensembl:ENSG00000275713(gene)|ensembl:ENST00000619466(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0097677"(STAT family protein binding)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:W+7KkrtV9xv7ELLxmJFnI4LQoME9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q6FI13 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-353620|uniprotkb:P20670|uniprotkb:B2R5F0|ensembl:ENSP00000358155|ensembl:ENSP00000475814 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2a2a_human(display_long)|uniprotkb:H2AC18(gene name)|psi-mi:H2AC18(display_short)|uniprotkb:H2AC19(gene name)|psi-mi:H2AC19(display_short)|uniprotkb:H2A-clustered histone 18(gene name synonym)|uniprotkb:H2A-clustered histone 19(gene name synonym)|uniprotkb:H2AFO(gene name synonym)|uniprotkb:HIST2H2AA(gene name synonym)|uniprotkb:HIST2H2AA3(gene name synonym)|uniprotkb:HIST2H2AA4(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/o(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_001035807.1|refseq:NP_003507.1|ensembl:ENSG00000203812(gene)|ensembl:ENSG00000272196(gene)|ensembl:ENST00000369159(transcript)|ensembl:ENST00000607355(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6Y5D|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|dip:DIP-33167N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:PMuIm2XMN5q4wk+wYJ94mmnCe4w9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q99877 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-744423|uniprotkb:Q494S8|uniprotkb:Q96FB7|uniprotkb:B2R5L4|ensembl:ENSP00000446031|ensembl:ENSP00000483903 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2b1n_human(display_long)|uniprotkb:H2BC15(gene name)|psi-mi:H2BC15(display_short)|uniprotkb:H2BFD(gene name synonym)|uniprotkb:HIST1H2BN(gene name synonym)|uniprotkb:Histone H2B.d(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_003511.1|ensembl:ENSG00000233822(gene)|ensembl:ENST00000449538(transcript)|ensembl:ENST00000612898(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:nGZETothwO57PuE11M5ogikaZkM9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q99729 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P58876 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-4409942|ensembl:ENSP00000289316|ensembl:ENSP00000367008 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2b1d_human(display_long)|uniprotkb:Histone H2B.b(gene name synonym)|uniprotkb:H2BC5(gene name)|psi-mi:H2BC5(display_short)|uniprotkb:H2B-clustered histone 5(gene name synonym)|uniprotkb:H2BFB(gene name synonym)|uniprotkb:HIRA-interacting protein 2(gene name synonym)|uniprotkb:HIRIP2(gene name synonym)|uniprotkb:HIST1H2BD(gene name synonym)|uniprotkb:Histone H2B.1 B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_066407.1|refseq:NP_619790.1|ensembl:ENSG00000158373(gene)|ensembl:ENST00000289316(transcript)|ensembl:ENST00000377777(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P58876|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005634"(nucleus) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:07VBw5MCphdkMydMOPSjVqpGriI9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 intact:EBI-6147672 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 - psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:p0c7m2_human(display_short)|psi-mi:EBI-6147672(display_long) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP uniprotkb:P0C7M2(uniprot-removed-ac) - - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 - intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P35268 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-354533|intact:EBI-1055963|uniprotkb:Q6IBD1|uniprotkb:B2R495|ensembl:ENSP00000346088 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:rl22_human(display_long)|uniprotkb:RPL22(gene name)|psi-mi:RPL22(display_short)|uniprotkb:Heparin-binding protein HBp15(gene name synonym)|uniprotkb:Epstein-Barr virus small RNA-associated protein(gene name synonym)|uniprotkb:EBER-associated protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL22(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_000974.1|ensembl:ENSG00000116251(gene)|ensembl:ENST00000234875(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008201"(heparin binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0045182"(translation regulator activity)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099577"(regulation of translation at presynapse, modulating synaptic transmission)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002671(Ribosomal protein L22e)|interpro:IPR038526|mint:P35268|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|reactome:R-HSA-72706|rcsb pdb:6Z6L|rcsb pdb:6Z6M|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:0TVillnqDkHmdTwxIedAJCVAdzY9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q9BTM1 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-4398590|uniprotkb:Q9NV63|ensembl:ENSP00000373730|ensembl:ENSP00000438553 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2aj_human(display_long)|uniprotkb:H2AJ(gene name)|psi-mi:H2AJ(display_short)|uniprotkb:H2AFJ(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_808760.1|ensembl:ENSG00000246705(gene)|ensembl:ENST00000389078(transcript)|ensembl:ENST00000544848(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:4EDU|rcsb pdb:6K60|rcsb pdb:6KVD|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-8939236 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:g6br63FeM17yJRfQI3GnmoM0vbc9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P63167 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P57053 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-2880265|ensembl:ENSP00000481622|uniprotkb:A0AVF9|uniprotkb:Q5R2W0 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2bfs_human(display_long)|uniprotkb:H2BS1(gene name)|psi-mi:H2BS1(display_short)|uniprotkb:H2B.S histone 1(gene name synonym)|uniprotkb:H2BFS(gene name synonym)|uniprotkb:Histone H2B.s(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP ensembl:ENSG00000234289(gene)|ensembl:ENST00000599962(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0021762"(substantia nigra development)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-427359|refseq:XP_006723981.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:x8Ryb6Tm0nfhcmsoTX5h5ZRsN7g9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q16777 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-5325566|ensembl:ENSP00000332194|uniprotkb:Q6DRA7|uniprotkb:Q8IUE5 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2a2c_human(display_long)|uniprotkb:H2AC20(gene name)|psi-mi:H2AC20(display_short)|uniprotkb:H2A-clustered histone 20(gene name synonym)|uniprotkb:H2AFQ(gene name synonym)|uniprotkb:HIST2H2AC(gene name synonym)|uniprotkb:Histone H2A-GL101(gene name synonym)|uniprotkb:Histone H2A/q(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-5689603|ensembl:ENSG00000184260(gene)|ensembl:ENST00000331380(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q16777|rcsb pdb:6Y5E|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|refseq:NP_003508.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:Wejrpp9wK3GvA4ahJDVyEH+cwlQ9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P20671 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-4407441|uniprotkb:A0PK91|uniprotkb:P57754|uniprotkb:Q6FGY6|ensembl:ENSP00000341094 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2a1d_human(display_long)|uniprotkb:H2AC7(gene name)|psi-mi:H2AC7(display_short)|uniprotkb:H2AFG(gene name synonym)|uniprotkb:HIST1H2AD(gene name synonym)|uniprotkb:Histone H2A.3(gene name synonym)|uniprotkb:Histone H2A/g(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_066409.1|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000196866(gene)|ensembl:ENST00000341023(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:5GT3|rcsb pdb:6KBB|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:Geraq+dGw3pvAAhgzzXQnYxDOOw9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P23527 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-1642161|uniprotkb:Q3KPI7|uniprotkb:Q8TCV6|ensembl:ENSP00000477527 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2b1o_human(display_long)|uniprotkb:H2BC17(gene name)|psi-mi:H2BC17(display_short)|uniprotkb:H2B-clustered histone 17(gene name synonym)|uniprotkb:H2BFH(gene name synonym)|uniprotkb:H2BFN(gene name synonym)|uniprotkb:HIST1H2BO(gene name synonym)|uniprotkb:Histone H2B.2(gene name synonym)|uniprotkb:Histone H2B.n(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_003518.2|ensembl:ENSG00000274641(gene)|ensembl:ENST00000616182(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P23527|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:vetsoCf1s6GUePoGq1wMLwz8obg9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P52597 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-352986|ensembl:ENSP00000338477|ensembl:ENSP00000349573|ensembl:ENSP00000400433|ensembl:ENSP00000438061|ensembl:ENSP00000507787|ensembl:ENSP00000348345|uniprotkb:Q5T0N2|uniprotkb:Q96AU2|uniprotkb:B3KM84 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:hnrpf_human(display_long)|uniprotkb:HNRNPF(gene name)|psi-mi:HNRNPF(display_short)|uniprotkb:HNRPF(gene name synonym)|uniprotkb:Nucleolin-like protein mcs94-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P52597|rcsb pdb:2HGL|rcsb pdb:2HGM|rcsb pdb:2HGN|rcsb pdb:2KFY|rcsb pdb:2KG0|rcsb pdb:2KG1|rcsb pdb:3TFY|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensembl:ENSG00000169813(gene)|ensembl:ENST00000337970(transcript)|ensembl:ENST00000356053(transcript)|ensembl:ENST00000357065(transcript)|ensembl:ENST00000443950(transcript)|ensembl:ENST00000544000(transcript)|ensembl:ENST00000682386(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001091674.1|refseq:NP_001091675.1|refseq:NP_001091676.1|refseq:NP_001091677.1|refseq:NP_001091678.1|refseq:NP_004957.1|dip:DIP-33145N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:pblzpldZOa5vlZ+zGQY9qyWCxaw9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q16778 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-1056125|uniprotkb:A3KMC7|uniprotkb:Q4KMY1|uniprotkb:Q5QNX0|uniprotkb:Q9UE88|uniprotkb:A8K110|ensembl:ENSP00000358151 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2b2e_human(display_long)|uniprotkb:H2BC21(gene name)|psi-mi:H2BC21(display_short)|uniprotkb:H2B-clustered histone 21(gene name synonym)|uniprotkb:H2BFQ(gene name synonym)|uniprotkb:HIST2H2BE(gene name synonym)|uniprotkb:Histone H2B-GL105(gene name synonym)|uniprotkb:Histone H2B.q(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_003519.1|ensembl:ENSG00000184678(gene)|ensembl:ENST00000369155(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q16778|rcsb pdb:4NFT|rcsb pdb:6A7U|rcsb pdb:6KBB|rcsb pdb:6M4D|rcsb pdb:6M4G|rcsb pdb:6M4H|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|rcsb pdb:7BXT|dip:DIP-39324N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:jh5U2ATjpAVt5DYOgr9YbcVdEzw9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P55795 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-352823|ensembl:ENSP00000361927|uniprotkb:Q9HHA7|uniprotkb:A1L400 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:hnrh2_human(display_long)|uniprotkb:HNRNPH2(gene name)|psi-mi:HNRNPH2(display_short)|uniprotkb:FTP3(gene name synonym)|uniprotkb:HNRPH2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein H'(gene name synonym)|uniprotkb:FTP-3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP ensembl:ENSG00000126945(gene)|ensembl:ENST00000316594(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P55795|rcsb pdb:1WEZ|rcsb pdb:1WG5|rcsb pdb:6DG1|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001027565.1|refseq:NP_062543.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:811j5syFsbk/QSaZv/ag9QsFUEQ9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P12036 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-2880271|uniprotkb:Q9UQ14|uniprotkb:Q9UJS7|uniprotkb:Q96HF8|uniprotkb:B4DYY4|ensembl:ENSP00000311997 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:nfh_human(display_long)|uniprotkb:NEFH(gene name)|psi-mi:NEFH(display_short)|uniprotkb:KIAA0845(gene name synonym)|uniprotkb:NFH(gene name synonym)|uniprotkb:200 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament triplet H protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_066554.2|ensembl:ENSG00000100285(gene)|ensembl:ENST00000310624(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005883"(neurofilament)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0061564"(axon development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR010790(Protein of unknown function DUF1388)|interpro:IPR018039|interpro:IPR033183|interpro:IPR039008|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:TXMrn6SWBHIYQY1loZfVvMo9PtU9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P09651 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-352662|uniprotkb:Q3MIB7|uniprotkb:Q6PJZ7|ensembl:ENSP00000341826|ensembl:ENSP00000503610|uniprotkb:A8K4Z8|intact:EBI-2556572 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:roa1_human(display_long)|uniprotkb:HNRNPA1(gene name)|psi-mi:HNRNPA1(display_short)|uniprotkb:HNRPA1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:Single-strand RNA-binding protein(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_002127.1|refseq:NP_112420.1|ensembl:ENSG00000135486(gene)|ensembl:ENST00000340913(transcript)|ensembl:ENST00000677210(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|rcsb pdb:2LYV|rcsb pdb:2UP1|rcsb pdb:4YOE|rcsb pdb:5MPG|rcsb pdb:5MPL|rcsb pdb:5ZGD|rcsb pdb:5ZGL|rcsb pdb:6BXX|rcsb pdb:6DCL|rcsb pdb:6J60|rcsb pdb:7BX7|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035198"(miRNA binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051170"(import into nucleus)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR034845|interpro:IPR035979|mint:P09651|rcsb pdb:1HA1|rcsb pdb:1L3K|rcsb pdb:1PGZ|rcsb pdb:1PO6|rcsb pdb:1U1K|rcsb pdb:1U1L|rcsb pdb:1U1M|rcsb pdb:1U1N|rcsb pdb:1U1O|rcsb pdb:1U1P|rcsb pdb:1U1Q|rcsb pdb:1U1R|rcsb pdb:1UP1|rcsb pdb:2H4M|refseq:XP_005268883.1|dip:DIP-29338N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:ECXjsLRVtNc/aOw90tEFxowHc6c9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:O60814 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-4409738|uniprotkb:A8K7P7|uniprotkb:Q2VPI7|ensembl:ENSP00000349430 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2b1k_human(display_long)|uniprotkb:H2BC12(gene name)|psi-mi:H2BC12(display_short)|uniprotkb:H2BFT(gene name synonym)|uniprotkb:HIRA-interacting protein 1(gene name synonym)|uniprotkb:HIRIP1(gene name synonym)|uniprotkb:HIST1H2BK(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_542160.1|refseq:NP_001299582.1|dip:DIP-48935N|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000197903(gene)|ensembl:ENST00000356950(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:O60814|rcsb pdb:2CV5|rcsb pdb:6KE9|rcsb pdb:6L9H|rcsb pdb:6LE9|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6V92|rcsb pdb:6Y5D|rcsb pdb:7BWD|rcsb pdb:7DBP|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:aBHcFUkMIdiiZov716H7kxmHzj09606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q96B45 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-6151489|uniprotkb:C9K0X3|uniprotkb:B3KUW4|uniprotkb:B2R488|ensembl:ENSP00000342331|ensembl:ENSP00000358899 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:borc7_human(display_long)|uniprotkb:BORCS7(gene name)|psi-mi:BORCS7(display_short)|uniprotkb:C10orf32(gene name synonym)|uniprotkb:Diaskedin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_001129672.1|refseq:NP_653192.2|ensembl:ENSG00000166275(gene)|ensembl:ENST00000339834(transcript)|ensembl:ENST00000369883(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0099078"(BORC complex)|interpro:IPR032143 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:nWmtuEe/BAme4MMt55fvFjyGNss9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q32P51 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-2556580|uniprotkb:Q5TBS2|ensembl:ENSP00000350090 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:ra1l2_human(display_long)|uniprotkb:HNRNPA1L(gene name synonym)|uniprotkb:HNRNPA1L2(gene name)|psi-mi:HNRNPA1L2(display_short)|uniprotkb:hnRNP core protein A1-like 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_001011724.1|refseq:NP_001011725.1|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0051028"(mRNA transport)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR035979|mint:Q32P51|go:"GO:0005681"(spliceosomal complex)|ensembl:ENSG00000139675(gene)|ensembl:ENST00000357495(transcript)|go:"GO:0003723"(RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:Xx00SLimJrf+0e9CrvzUV9PJPcI9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q96KK5 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-6147668|ensembl:ENSP00000366679 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2a1h_human(display_long)|uniprotkb:H2AC12(gene name)|psi-mi:H2AC12(display_short)|uniprotkb:H2A-clustered histone 12(gene name synonym)|uniprotkb:HIST1H2AH(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:Histone H2A/s(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_542163.1|dip:DIP-61699N|ensembl:ENSG00000274997(gene)|ensembl:ENST00000377459(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:Oa322n+evy8Cu0E9cWTEdYwQPKM9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q5QNW6 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-6147754|uniprotkb:B4DLA9|uniprotkb:A8K0U9|ensembl:ENSP00000358164 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2b2f_human(display_long)|uniprotkb:H2BC18(gene name)|psi-mi:H2BC18(display_short)|uniprotkb:H2B-clustered histone 18(gene name synonym)|uniprotkb:HIST2H2BF(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_001019770.1|refseq:NP_001154806.1|ensembl:ENSG00000203814(gene)|ensembl:ENST00000369167(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q5QNW6|rcsb pdb:6MUO|rcsb pdb:6MUP|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-5689880|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:Pr400UVIaD7O446lc9vZeStUKn09606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q969J3 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-747707|uniprotkb:Q96QS5|ensembl:ENSP00000321546|ensembl:ENSP00000486120 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:borc5_human(display_long)|uniprotkb:BORCS5(gene name)|psi-mi:BORCS5(display_short)|uniprotkb:LOH12CR1(gene name synonym)|uniprotkb:Loss of heterozygosity 12 chromosomal region 1(gene name synonym)|uniprotkb:Myristoylated lysosomal protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_477517.1|refseq:NP_001287671.1|ensembl:ENST00000298571|ensembl:ENSP00000298571|ensembl:ENSP00000321546|ensembl:ENSP00000486120|ensembl:ENST00000627461|ensembl:ENSP00000486584|refseq:NP_001317285.1|ensembl:ENSG00000165714(gene)|ensembl:ENSG00000280689(gene)|ensembl:ENST00000314565(transcript)|ensembl:ENST00000627374(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0072384"(organelle transport along microtubule)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:0099078"(BORC complex)|go:"GO:1903744"(positive regulation of anterograde synaptic vesicle transport)|interpro:IPR018780 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:T9UGkdhlIbXuaKLTa0TyzxsbM9w9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P04908 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:4Qno1mMYZB6FdNoojrzulWLVq849606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P62805 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q7L7L0 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-5325551|ensembl:ENSP00000355656|ensembl:ENSP00000493926|uniprotkb:B2R4S4 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2a3_human(display_long)|uniprotkb:H2AW(gene name)|psi-mi:H2AW(display_short)|uniprotkb:HIST3H2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP ensembl:ENSG00000181218(gene)|ensembl:ENSG00000284841(gene)|ensembl:ENST00000366695(transcript)|refseq:NP_254280.1|ensembl:ENST00000645741(transcript)|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-5689603|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q7L7L0|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000786"(nucleosome)|dip:DIP-48936N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:t0RdR1SmUtmwRjtCS3uTyLGqSUI9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P62807 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-354552|uniprotkb:Q4VB69|uniprotkb:P02278|uniprotkb:Q3B872|uniprotkb:Q93078|uniprotkb:Q93080|ensembl:ENSP00000321744|ensembl:ENSP00000348924|ensembl:ENSP00000366962|ensembl:ENSP00000380180|ensembl:ENSP00000445633|ensembl:ENSP00000483237|ensembl:ENSP00000489317 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2b1c_human(display_long)|uniprotkb:HIST1H2BG(gene name synonym)|uniprotkb:HIST1H2BI(gene name synonym)|uniprotkb:Histone H2B.1 A(gene name synonym)|uniprotkb:Histone H2B.a(gene name synonym)|uniprotkb:Histone H2B.g(gene name synonym)|uniprotkb:Histone H2B.h(gene name synonym)|uniprotkb:Histone H2B.k(gene name synonym)|uniprotkb:Histone H2B.l(gene name synonym)|uniprotkb:H2BC10(gene name)|psi-mi:H2BC10(display_short)|uniprotkb:H2BC4(gene name)|psi-mi:H2BC4(display_short)|uniprotkb:H2BC6(gene name)|psi-mi:H2BC6(display_short)|uniprotkb:H2BC7(gene name)|psi-mi:H2BC7(display_short)|uniprotkb:H2BC8(gene name)|psi-mi:H2BC8(display_short)|uniprotkb:H2BFA(gene name synonym)|uniprotkb:H2BFG(gene name synonym)|uniprotkb:H2BFH(gene name synonym)|uniprotkb:H2BFK(gene name synonym)|uniprotkb:H2BFL(gene name synonym)|uniprotkb:HIST1H2BC(gene name synonym)|uniprotkb:HIST1H2BE(gene name synonym)|uniprotkb:HIST1H2BF(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_003509.1|refseq:NP_003513.1|refseq:NP_003514.2|refseq:NP_003516.1|refseq:NP_003517.2|refseq:NP_066407.1|rcsb pdb:7A08|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|rcsb pdb:6XJD|ensembl:ENSG00000180596(gene)|ensembl:ENSG00000273802(gene)|ensembl:ENSG00000274290(gene)|ensembl:ENSG00000277224(gene)|ensembl:ENSG00000278588(gene)|ensembl:ENST00000314332(transcript)|ensembl:ENST00000356530(transcript)|ensembl:ENST00000377733(transcript)|ensembl:ENST00000396984(transcript)|ensembl:ENST00000541790(transcript)|ensembl:ENST00000614097(transcript)|ensembl:ENST00000634910(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0042802"(identical protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P62807|rcsb pdb:5GT0|rcsb pdb:5KGF|rcsb pdb:6ACO|rcsb pdb:6C0W|rcsb pdb:6FML|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6X59|rcsb pdb:6X5A|dip:DIP-32890N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:00sapwbWn8dtUr7qoPsRPUlL35A9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P06899 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-6150252|uniprotkb:B2R4J4|uniprotkb:O60816|ensembl:ENSP00000342886|ensembl:ENSP00000476136 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2b1j_human(display_long)|uniprotkb:H2BC11(gene name)|psi-mi:H2BC11(display_short)|uniprotkb:H2BFR(gene name synonym)|uniprotkb:HIST1H2BJ(gene name synonym)|uniprotkb:Histone H2B.1(gene name synonym)|uniprotkb:Histone H2B.r(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_066402.2|dip:DIP-421N|ensembl:ENSG00000124635(gene)|ensembl:ENST00000339812(transcript)|ensembl:ENST00000607124(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P06899|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WAA|rcsb pdb:3WTP|rcsb pdb:4CAY|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5FUG|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5VEY|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6YOV|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7K5X|rcsb pdb:3WA9|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:74GQlSjGG1Ez6Uog74VXPLryKBc9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q99880 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-1237119|uniprotkb:Q52LW9|uniprotkb:B2R5A3|ensembl:ENSP00000366618 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2b1l_human(display_long)|uniprotkb:H2BC13(gene name)|psi-mi:H2BC13(display_short)|uniprotkb:H2BFC(gene name synonym)|uniprotkb:HIST1H2BL(gene name synonym)|uniprotkb:Histone H2B.c(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_003510.1|dip:DIP-38154N|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|ensembl:ENSG00000185130(gene)|ensembl:ENST00000377401(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|interpro:IPR009072(Histone-fold)|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5250924|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:vVD3xoHavMKCopzEez7zarZBKFc9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P0C0S8 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P12273 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-1049746|uniprotkb:A0A963|uniprotkb:A0A9C3|uniprotkb:A0A9F3|uniprotkb:A4D2I1|ensembl:ENSP00000291009 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:pip_human(display_long)|uniprotkb:Prolactin-induced protein(gene name synonym)|uniprotkb:Secretory actin-binding protein(gene name synonym)|uniprotkb:Gross cystic disease fluid protein 15(gene name synonym)|uniprotkb:gp17(gene name synonym)|uniprotkb:PIP(gene name)|psi-mi:PIP(display_short)|uniprotkb:GCDFP15(gene name synonym)|uniprotkb:GPIP4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_002643.1|ensembl:ENSG00000159763(gene)|ensembl:ENST00000291009(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0003779"(actin binding)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006508"(proteolysis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019864"(IgG binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|interpro:IPR007990(Seminal vesicle autoantigen)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|mint:P12273|rcsb pdb:3ES6|reactome:R-HSA-5223345|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:/OC16zeRzFp520uPPLHh+WekPPc9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q93077 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-725259|uniprotkb:O00775|uniprotkb:O00776|uniprotkb:O00777|uniprotkb:O00778|uniprotkb:Q540R1|uniprotkb:B2R4F7|ensembl:ENSP00000321389|ensembl:ENSP00000367022|ensembl:ENSP00000473534 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2a1c_human(display_long)|uniprotkb:H2AC6(gene name)|psi-mi:H2AC6(display_short)|uniprotkb:H2A-clustered histone 6(gene name synonym)|uniprotkb:H2AFL(gene name synonym)|uniprotkb:HIST1H2AC(gene name synonym)|uniprotkb:Histone H2A/l(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_003503.1|ensembl:ENSG00000180573(gene)|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENST00000314088(transcript)|ensembl:ENST00000377791(transcript)|ensembl:ENST00000602637(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|rcsb pdb:6C0W|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:7A08|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|interpro:IPR032458 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:m00IdooZksbNGKHSsaVvGFVpcko9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P31943 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168|ensembl:ENSP00000377082|ensembl:ENSP00000397797|ensembl:ENSP00000492076|ensembl:ENSP00000495786 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_005511.1|refseq:NP_001244222.1|ensembl:ENSG00000169045(gene)|ensembl:ENSG00000284254(gene)|ensembl:ENST00000356731(transcript)|ensembl:ENST00000393432(transcript)|ensembl:ENST00000442819(transcript)|ensembl:ENST00000638505(transcript)|ensembl:ENST00000643310(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P78537 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-348630|uniprotkb:Q6NZ45|uniprotkb:A1L4Q9|ensembl:ENSP00000447537 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:bl1s1_human(display_long)|uniprotkb:BLOC1S1(gene name)|psi-mi:BLOC1S1(display_short)|uniprotkb:BLOS1(gene name synonym)|uniprotkb:RT14(gene name synonym)|uniprotkb:GCN5L1(gene name synonym)|uniprotkb:GCN5-like protein 1(gene name synonym)|uniprotkb:Protein RT14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_001478.2|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR009395(GCN5-like 1)|mint:P78537|reactome:R-HSA-432720|reactome:R-HSA-432722|ensembl:ENSG00000135441(gene)|ensembl:ENST00000548925(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016197"(endosomal transport)|go:"GO:0018394"(peptidyl-lysine acetylation) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:lntB3izez0HoFLPpiAtPBayt+G49606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P22626 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q6P2E9 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP ensembl:ENSG00000038358(gene)|interpro:IPR036322|mint:Q6P2E9|reactome:R-HSA-430039|ensembl:ENST00000358933(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|refseq:NP_055144.3|dip:DIP-31192N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:P31942 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-711437|uniprotkb:Q9NPI4|uniprotkb:Q9UFU4|uniprotkb:Q9Y4J5|uniprotkb:Q9BSX1|uniprotkb:Q9NP53|uniprotkb:Q9NP96|uniprotkb:Q9NPA7|ensembl:ENSP00000265866|uniprotkb:A8K682|uniprotkb:B3KRE1 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:hnrh3_human(display_long)|uniprotkb:HNRNPH3(gene name)|psi-mi:HNRNPH3(display_short)|uniprotkb:HNRPH3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein 2H9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP ensembl:ENSG00000096746(gene)|ensembl:ENST00000265866(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034969|interpro:IPR034970|interpro:IPR035979|mint:P31942|refseq:NP_036339.1|refseq:NP_067676.2|refseq:NP_001309363.1|refseq:NP_001309365.1|refseq:NP_001309366.1|refseq:NP_001309367.1|refseq:NP_001309368.1|refseq:NP_001309369.1|refseq:NP_001309370.1|refseq:NP_001309374.1|refseq:NP_001309375.1|refseq:NP_001309376.1|refseq:NP_001309377.1|refseq:NP_001309378.1|refseq:XP_016871657.1|refseq:XP_016871658.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:iJGBIhPXnQIIFQmgxWB1WjwVXSY9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05127 uniprotkb:Q8N257 intact:EBI-6148294|uniprotkb:Q8JS63|uniprotkb:Q77LU7 intact:EBI-6150245|uniprotkb:Q5TA30|uniprotkb:Q3ZCP6|uniprotkb:A4FU05|ensembl:ENSP00000479284|ensembl:ENSP00000496342 psi-mi:vp35_ebozm(display_long)|uniprotkb:VP35(gene name)|psi-mi:VP35(display_short)|uniprotkb:Ebola VP35(gene name synonym) psi-mi:h2b3b_human(display_long)|uniprotkb:H2BU1(gene name)|psi-mi:H2BU1(display_short)|uniprotkb:H2B type 12(gene name synonym)|uniprotkb:H2B.U histone 1(gene name synonym)|uniprotkb:HIST3H2BB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158326|imex:IM-17331-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066244.1|dip:DIP-48771N|go:"GO:0003723"(RNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0039501"(suppression by virus of host type I interferon production)|go:"GO:0039505"(suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II)|go:"GO:0039557"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039722"(suppression by virus of host toll-like receptor signaling pathway)|go:"GO:0039723"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity)|go:"GO:0039724"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity)|go:"GO:0044414"(suppression of host defenses by symbiont)|go:"GO:0046775"(suppression by virus of host cytokine production)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|interpro:IPR002953(Filoviridae VP35 protein)|interpro:IPR031163|interpro:IPR043060|interpro:IPR043061|rcsb pdb:3FKE|rcsb pdb:3L25|rcsb pdb:3L26|rcsb pdb:3L27|rcsb pdb:3L28|rcsb pdb:3L29|rcsb pdb:4IBB|rcsb pdb:4IBC|rcsb pdb:4IBD|rcsb pdb:4IBE|rcsb pdb:4IBF|rcsb pdb:4IBG|rcsb pdb:4IBI|rcsb pdb:4IBJ|rcsb pdb:4IBK|rcsb pdb:4IJE|rcsb pdb:4IJF|rcsb pdb:4YPI|rcsb pdb:4ZTA|rcsb pdb:4ZTG|rcsb pdb:4ZTI|rcsb pdb:6GBO|rcsb pdb:6GBP refseq:NP_778225.1|ensembl:ENSG00000196890(gene)|ensembl:ENSG00000285449(gene)|ensembl:ENST00000620438(transcript)|ensembl:ENST00000647549(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q8N257|rcsb pdb:6BIZ|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/02/20 rogid:dNxhJ6s484zTGfDLnmoGqE+MlMc128952 rogid:MnRK2NXd2p3rWO8GPfErAa273eY9606 intact-crc:68AE41006DB81E1D false mutation:309-309,312-312,305-305|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:Q7L7L0 intact:EBI-6151657 intact:EBI-5325551|ensembl:ENSP00000355656|ensembl:ENSP00000493926|uniprotkb:B2R4S4 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a3_human(display_long)|uniprotkb:H2AW(gene name)|psi-mi:H2AW(display_short)|uniprotkb:HIST3H2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 ensembl:ENSG00000181218(gene)|ensembl:ENSG00000284841(gene)|ensembl:ENST00000366695(transcript)|refseq:NP_254280.1|ensembl:ENST00000645741(transcript)|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-5689603|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q7L7L0|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000786"(nucleosome)|dip:DIP-48936N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:t0RdR1SmUtmwRjtCS3uTyLGqSUI9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:Q9UGM3 intact:EBI-6151657 intact:EBI-1044970|uniprotkb:Q59EX0|uniprotkb:Q5JR26|uniprotkb:Q6MZN4|uniprotkb:Q96DU4|uniprotkb:Q9UGM2|uniprotkb:Q9UJ57|uniprotkb:Q9UKJ4|uniprotkb:Q9Y211|uniprotkb:Q9Y4V9|uniprotkb:A6NDG4|uniprotkb:A6NDJ5|uniprotkb:A8E4R5|uniprotkb:B1ARE7|uniprotkb:B1ARE8|uniprotkb:B1ARE9|uniprotkb:B1ARF0|uniprotkb:B7Z8Y2|uniprotkb:F8WEF7|ensembl:ENSP00000357905|ensembl:ENSP00000484603|ensembl:ENSP00000498825 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:dmbt1_human(display_long)|uniprotkb:Glycoprotein 340(gene name synonym)|uniprotkb:Surfactant pulmonary-associated D-binding protein(gene name synonym)|uniprotkb:Hensin(gene name synonym)|uniprotkb:DMBT1(gene name)|psi-mi:DMBT1(display_short)|uniprotkb:GP340(gene name synonym)|uniprotkb:Salivary agglutinin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_004397.2|refseq:NP_015568.2|refseq:NP_060049.2|refseq:XP_011537690.1|refseq:XP_011537693.1|refseq:XP_011537707.1|refseq:NP_001307573.1|dip:DIP-50763N|ensembl:ENSG00000187908(gene)|ensembl:ENST00000368909(transcript)|ensembl:ENST00000619379(transcript)|ensembl:ENST00000652446(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006952"(defense response)|go:"GO:0015031"(protein transport)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035375"(zymogen binding)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042494"(detection of bacterial lipoprotein)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0045087"(innate immune response)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070891"(lipoteichoic acid binding)|go:"GO:1904399"(heparan sulfate binding)|interpro:IPR000859(CUB)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR001507(Endoglin/CD105 antigen)|interpro:IPR017448(Speract/scavenger receptor related)|interpro:IPR017977|interpro:IPR035914|interpro:IPR036772|interpro:IPR042235|mint:Q9UGM3|rcsb pdb:6SA4|rcsb pdb:6SA5|rcsb pdb:6SAN|reactome:R-HSA-5683826 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:A0Aw2F/rHW8mFmPDg4xOTy8NGzg9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P52630 intact:EBI-6151657 intact:EBI-1546963|uniprotkb:Q16430|uniprotkb:Q16431|uniprotkb:Q9UDL4|intact:EBI-10989287|uniprotkb:B4DLC7|uniprotkb:G3V2M6|ensembl:ENSP00000315768 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:stat2_human(display_long)|uniprotkb:p113(gene name synonym)|uniprotkb:STAT2(gene name)|psi-mi:STAT2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_005410.1|refseq:NP_938146.1|dip:DIP-38511N|ensembl:ENSG00000170581(gene)|ensembl:ENST00000314128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0090140"(regulation of mitochondrial fission)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022756|interpro:IPR035854|interpro:IPR036535|interpro:IPR036860|mint:P52630|rcsb pdb:2KA4|rcsb pdb:6UX2|rcsb pdb:6WCZ|reactome:R-HSA-8854691|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9679191 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:uA0lxm5vmrLClQRP7NItd0/u4Ko9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P0CF74 intact:EBI-6151657 intact:EBI-6151653 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:iglc6_human(display_long)|uniprotkb:IGLC6(gene name)|psi-mi:IGLC6(display_short)|uniprotkb:Ig lambda-6 chain C region(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 reactome:R-HSA-202733|interpro:IPR036179|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-983695|reactome:R-HSA-977606|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:BzDLpEqjHGJsx9Do9D9pFPdi5rE9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P01834 intact:EBI-6151657 intact:EBI-1054530|uniprotkb:A0A075B6H6|uniprotkb:A0A087X130 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:igkc_human(display_long)|uniprotkb:IGKC(gene name)|psi-mi:IGKC(display_short)|uniprotkb:Ig kappa chain C region(gene name synonym)|uniprotkb:Ig kappa chain C region AG(gene name synonym)|uniprotkb:Ig kappa chain C region CUM(gene name synonym)|uniprotkb:Ig kappa chain C region EU(gene name synonym)|uniprotkb:Ig kappa chain C region OU(gene name synonym)|uniprotkb:Ig kappa chain C region ROY(gene name synonym)|uniprotkb:Ig kappa chain C region TI(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 rcsb pdb:2NY7|rcsb pdb:1N0X|rcsb pdb:4NM4|rcsb pdb:4NM8|rcsb pdb:6N2X|rcsb pdb:6N32|rcsb pdb:6N35|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XNZ|rcsb pdb:4XXD|rcsb pdb:4YDV|rcsb pdb:4D3C|rcsb pdb:3X11|rcsb pdb:3X12|rcsb pdb:5ESV|rcsb pdb:5ESZ|reactome:R-HSA-5690714|rcsb pdb:6OGE|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|rcsb pdb:1A4J|rcsb pdb:1A4K|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1HEZ|rcsb pdb:1HKL|rcsb pdb:1I7Z|rcsb pdb:1MIM|rcsb pdb:1UCB|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QSC|rcsb pdb:2R56|rcsb pdb:2VXQ|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D85|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3VH8|rcsb pdb:5B39|rcsb pdb:5B38|reactome:R-HSA-202733|rcsb pdb:3U0W|rcsb pdb:1DFB|rcsb pdb:3WUW|rcsb pdb:1HZH|rcsb pdb:3O11|rcsb pdb:3QCT|rcsb pdb:3QCU|rcsb pdb:3QCV|rcsb pdb:4D9R|rcsb pdb:4HIX|go:"GO:0001895"(retina homeostasis)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:1CLY|rcsb pdb:1GAF|rcsb pdb:2RFX|rcsb pdb:3IU3|rcsb pdb:3RU8|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-983695|rcsb pdb:6AU5|rcsb pdb:6AXP|rcsb pdb:6AYN|rcsb pdb:6AZK|rcsb pdb:6AZL|reactome:R-HSA-977606|rcsb pdb:7CZY|rcsb pdb:7CZZ|rcsb pdb:5VEB|rcsb pdb:5VIY|interpro:IPR036179|rcsb pdb:6B9Y|rcsb pdb:6B9Z|rcsb pdb:6BAE|rcsb pdb:6BAH|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6OKP|reactome:R-HSA-9664323|reactome:R-HSA-9664422 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:TlqDc4NqqQkVNViyRU/dy+tYX2c9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P20671 intact:EBI-6151657 intact:EBI-4407441|uniprotkb:A0PK91|uniprotkb:P57754|uniprotkb:Q6FGY6|ensembl:ENSP00000341094 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a1d_human(display_long)|uniprotkb:H2AC7(gene name)|psi-mi:H2AC7(display_short)|uniprotkb:H2AFG(gene name synonym)|uniprotkb:HIST1H2AD(gene name synonym)|uniprotkb:Histone H2A.3(gene name synonym)|uniprotkb:Histone H2A/g(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_066409.1|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000196866(gene)|ensembl:ENST00000341023(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:5GT3|rcsb pdb:6KBB|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:Geraq+dGw3pvAAhgzzXQnYxDOOw9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P04406 intact:EBI-6151657 intact:EBI-354056|uniprotkb:P00354|uniprotkb:Q53X65|uniprotkb:E7EUT4|ensembl:ENSP00000229239|ensembl:ENSP00000380068|ensembl:ENSP00000380070 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:g3p_human(display_long)|uniprotkb:GAPDH(gene name)|psi-mi:GAPDH(display_short)|uniprotkb:OK/SW-cl.12(orf name)|uniprotkb:CDABP0047(orf name)|uniprotkb:GAPD(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_002037.2|refseq:NP_001243728.1|refseq:NP_001276674.1|refseq:NP_001276675.1|dip:DIP-32521N|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P04406|rcsb pdb:1U8F|rcsb pdb:1ZNQ|rcsb pdb:2FEH|rcsb pdb:3GPD|rcsb pdb:4WNC|rcsb pdb:4WNI|rcsb pdb:6ADE|rcsb pdb:6M61|rcsb pdb:6YND|rcsb pdb:6YNE|rcsb pdb:6YNF|rcsb pdb:6YNH|reactome:R-HSA-70171|reactome:R-HSA-70263|rcsb pdb:6IQ6|ensembl:ENSG00000111640(gene)|ensembl:ENST00000229239(transcript)|ensembl:ENST00000396859(transcript)|ensembl:ENST00000396861(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0031640"(killing of cells of another organism) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:9YENN/dfKl/d0tJtfFyQp2o8eAc9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P0CG04 intact:EBI-6151657 intact:EBI-1221063|uniprotkb:P80423|uniprotkb:A0M8Q4|uniprotkb:P01842|uniprotkb:A0A075B6K8 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:iglc1_human(display_long)|uniprotkb:IGLC1(gene name)|psi-mi:IGLC1(display_short)|uniprotkb:Ig lambda chain C region MGC(gene name synonym)|uniprotkb:Ig lambda-1 chain C region(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|mint:P0CG04|interpro:IPR036179|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:1ZVO|rcsb pdb:2FB4|rcsb pdb:2IG2|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|go:"GO:0045087"(innate immune response)|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695|reactome:R-HSA-9664323 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:OOdxBXPI2Jzf9HxurFZjk3/L1DM9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:Q6FI13 intact:EBI-6151657 intact:EBI-353620|uniprotkb:P20670|uniprotkb:B2R5F0|ensembl:ENSP00000358155|ensembl:ENSP00000475814 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a2a_human(display_long)|uniprotkb:H2AC18(gene name)|psi-mi:H2AC18(display_short)|uniprotkb:H2AC19(gene name)|psi-mi:H2AC19(display_short)|uniprotkb:H2A-clustered histone 18(gene name synonym)|uniprotkb:H2A-clustered histone 19(gene name synonym)|uniprotkb:H2AFO(gene name synonym)|uniprotkb:HIST2H2AA(gene name synonym)|uniprotkb:HIST2H2AA3(gene name synonym)|uniprotkb:HIST2H2AA4(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/o(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_001035807.1|refseq:NP_003507.1|ensembl:ENSG00000203812(gene)|ensembl:ENSG00000272196(gene)|ensembl:ENST00000369159(transcript)|ensembl:ENST00000607355(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6Y5D|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|dip:DIP-33167N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:PMuIm2XMN5q4wk+wYJ94mmnCe4w9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:O60814 intact:EBI-6151657 intact:EBI-4409738|uniprotkb:A8K7P7|uniprotkb:Q2VPI7|ensembl:ENSP00000349430 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2b1k_human(display_long)|uniprotkb:H2BC12(gene name)|psi-mi:H2BC12(display_short)|uniprotkb:H2BFT(gene name synonym)|uniprotkb:HIRA-interacting protein 1(gene name synonym)|uniprotkb:HIRIP1(gene name synonym)|uniprotkb:HIST1H2BK(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_542160.1|refseq:NP_001299582.1|dip:DIP-48935N|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000197903(gene)|ensembl:ENST00000356950(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:O60814|rcsb pdb:2CV5|rcsb pdb:6KE9|rcsb pdb:6L9H|rcsb pdb:6LE9|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6V92|rcsb pdb:6Y5D|rcsb pdb:7BWD|rcsb pdb:7DBP|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:aBHcFUkMIdiiZov716H7kxmHzj09606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P12838 intact:EBI-6151657 intact:EBI-6151649|uniprotkb:Q6EZF8|ensembl:ENSP00000297435|ensembl:ENSP00000493844 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:def4_human(display_long)|uniprotkb:DEF4(gene name synonym)|uniprotkb:Defensin, alpha 4(gene name synonym)|uniprotkb:HNP-4(gene name synonym)|uniprotkb:DEFA4(gene name)|psi-mi:DEFA4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_001916.1|ensembl:ENSG00000164821(gene)|ensembl:ENSG00000285318(gene)|ensembl:ENST00000297435(transcript)|ensembl:ENST00000642522(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005796"(Golgi lumen)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042582"(azurophil granule)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045087"(innate immune response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051673"(membrane disruption in another organism)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0071222"(cellular response to lipopolysaccharide)|interpro:IPR002366(Defensin propeptide)|interpro:IPR006080(Mammalian defensin)|interpro:IPR006081(Alpha defensin)|interpro:IPR016327(Alpha-defensin)|rcsb pdb:1ZMM|rcsb pdb:6DMM|rcsb pdb:6DMQ|reactome:R-HSA-1461973|reactome:R-HSA-1462054|reactome:R-HSA-6798695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:7uYoWavwp4J+TrI9OKW89qf/Rfw9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:Q93079 intact:EBI-6151657 intact:EBI-352469|uniprotkb:Q4VB74|uniprotkb:B2R541|ensembl:ENSP00000479169 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2b1h_human(display_long)|uniprotkb:H2BC9(gene name)|psi-mi:H2BC9(display_short)|uniprotkb:H2B-clustered histone 9(gene name synonym)|uniprotkb:H2BFJ(gene name synonym)|uniprotkb:HIST1H2BH(gene name synonym)|uniprotkb:Histone H2B.j(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_003515.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|ensembl:ENSG00000275713(gene)|ensembl:ENST00000619466(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0097677"(STAT family protein binding)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:W+7KkrtV9xv7ELLxmJFnI4LQoME9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P59666 intact:EBI-6151657 intact:EBI-2817253|uniprotkb:P11479|uniprotkb:Q14125|ensembl:ENSP00000328359 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:def3_human(display_long)|uniprotkb:DEFA3(gene name)|psi-mi:DEFA3(display_short)|uniprotkb:DEF3(gene name synonym)|uniprotkb:Defensin, alpha 3(gene name synonym)|uniprotkb:HNP-3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_005208.1|ensembl:ENSG00000239839(gene)|ensembl:ENST00000327857(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005796"(Golgi lumen)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051673"(membrane disruption in another organism)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|interpro:IPR002366(Defensin propeptide)|interpro:IPR006080(Mammalian defensin)|interpro:IPR006081(Alpha defensin)|interpro:IPR016327(Alpha-defensin)|rcsb pdb:1DFN|rcsb pdb:1ZMH|rcsb pdb:1ZMI|rcsb pdb:1ZMK|rcsb pdb:2PM4|rcsb pdb:2PM5|reactome:R-HSA-1461973|reactome:R-HSA-1462054 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:0w7ijvs9Ev0J+NcfthNRiq4qt8c9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:Q99878 intact:EBI-6151657 intact:EBI-6147676|uniprotkb:Q5JXQ5|uniprotkb:A2RUU6|ensembl:ENSP00000328484 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a1j_human(display_long)|uniprotkb:H2AC14(gene name)|psi-mi:H2AC14(display_short)|uniprotkb:H2AFE(gene name synonym)|uniprotkb:HIST1H2AJ(gene name synonym)|uniprotkb:Histone H2A/e(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_066544.1|ensembl:ENSG00000276368(gene)|ensembl:ENST00000333151(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:tS29VG3PpglHaYbu0w5z7pGvYyI9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P27348 intact:EBI-6151657 intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081|ensembl:ENSP00000371267 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_006817.1|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|ensembl:ENSG00000134308(gene)|ensembl:ENST00000238081(transcript)|ensembl:ENST00000381844(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|dip:DIP-27584N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P59665 intact:EBI-6151657 intact:EBI-726336|uniprotkb:P11479|uniprotkb:Q14125|intact:EBI-2556097|uniprotkb:Q6EZF6|ensembl:ENSP00000372126|ensembl:ENSP00000372136|ensembl:ENSP00000372139|ensembl:ENSP00000493747|ensembl:ENSP00000496058|ensembl:ENSP00000496340|ensembl:ENSP00000496578 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:def1_human(display_long)|uniprotkb:HNP-1(gene name synonym)|uniprotkb:Defensin, alpha 1(gene name synonym)|uniprotkb:DEFA1(gene name)|psi-mi:DEFA1(display_short)|uniprotkb:DEF1(gene name synonym)|uniprotkb:DEFA2(gene name synonym)|uniprotkb:MRS(gene name synonym)|uniprotkb:DEFA1B(gene name)|psi-mi:DEFA1B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_001035965.1|refseq:NP_004075.1|ensembl:ENSG00000206047(gene)|ensembl:ENSG00000240247(gene)|ensembl:ENSG00000284983(gene)|ensembl:ENSG00000285176(gene)|ensembl:ENST00000382679(transcript)|ensembl:ENST00000382689(transcript)|ensembl:ENST00000382692(transcript)|ensembl:ENST00000644528(transcript)|ensembl:ENST00000644617(transcript)|ensembl:ENST00000644834(transcript)|ensembl:ENST00000645146(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005796"(Golgi lumen)|go:"GO:0006935"(chemotaxis)|go:"GO:0006955"(immune response)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0044657"(obsolete pore formation in membrane of other organism during symbiotic interaction)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051607"(defense response to virus)|go:"GO:0051673"(membrane disruption in another organism)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|interpro:IPR002366(Defensin propeptide)|interpro:IPR006080(Mammalian defensin)|interpro:IPR006081(Alpha defensin)|interpro:IPR016327(Alpha-defensin)|rcsb pdb:2KHT|rcsb pdb:2PM1|rcsb pdb:3GNY|rcsb pdb:3H6C|rcsb pdb:3HJ2|rcsb pdb:3HJD|rcsb pdb:3LO1|rcsb pdb:3LO2|rcsb pdb:3LO4|rcsb pdb:3LO6|rcsb pdb:3LO9|rcsb pdb:3LOE|rcsb pdb:3LVX|rcsb pdb:4DU0|rcsb pdb:4LB1|rcsb pdb:4LB7|rcsb pdb:4LBB|rcsb pdb:4LBF|reactome:R-HSA-1461973|reactome:R-HSA-1462054|reactome:R-HSA-6798695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:lvnJBUVGDnll0UfiZA/ZeWOqw5I9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:Q13185 intact:EBI-6151657 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P0CG06 intact:EBI-6151657 intact:EBI-6151643|uniprotkb:P80423|uniprotkb:A0M8Q4 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:lac3_human(display_long)|uniprotkb:IGLC3(gene name)|psi-mi:IGLC3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-983695|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0072562"(blood microparticle)|go:"GO:0003823"(antigen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0045087"(innate immune response)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|rcsb pdb:1AQK|rcsb pdb:7FAB|go:"GO:0005615"(extracellular space)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0006956"(complement activation)|go:"GO:0050776"(regulation of immune response)|reactome:R-HSA-5690714 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:55z5fnrBdudlQP7eZNm2JHP1G6Y9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P01859 intact:EBI-6151657 intact:EBI-1044662|uniprotkb:A6NE66|ensembl:ENSP00000374987|ensembl:ENSP00000480351 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:ighg2_human(display_long)|uniprotkb:IGHG2(gene name)|psi-mi:IGHG2(display_short)|uniprotkb:Ig gamma-2 chain C region(gene name synonym)|uniprotkb:Ig gamma-2 chain C region DOT(gene name synonym)|uniprotkb:Ig gamma-2 chain C region TIL(gene name synonym)|uniprotkb:Ig gamma-2 chain C region ZIE(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|rcsb pdb:4L4J|ensembl:ENSG00000211893(gene)|ensembl:ENSG00000274497(gene)|ensembl:ENST00000390545(transcript)|ensembl:ENST00000621803(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2QSC|rcsb pdb:4HAF|rcsb pdb:4HAG - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:EZkOg27Ga0FblVGpeMMQzW0s/xo9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:Q16777 intact:EBI-6151657 intact:EBI-5325566|ensembl:ENSP00000332194|uniprotkb:Q6DRA7|uniprotkb:Q8IUE5 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a2c_human(display_long)|uniprotkb:H2AC20(gene name)|psi-mi:H2AC20(display_short)|uniprotkb:H2A-clustered histone 20(gene name synonym)|uniprotkb:H2AFQ(gene name synonym)|uniprotkb:HIST2H2AC(gene name synonym)|uniprotkb:Histone H2A-GL101(gene name synonym)|uniprotkb:Histone H2A/q(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-5689603|ensembl:ENSG00000184260(gene)|ensembl:ENST00000331380(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q16777|rcsb pdb:6Y5E|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|refseq:NP_003508.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:Wejrpp9wK3GvA4ahJDVyEH+cwlQ9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P63104 intact:EBI-6151657 intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:O00629 intact:EBI-6151657 intact:EBI-396343|uniprotkb:O00190|intact:EBI-28976443|ensembl:ENSP00000334373|uniprotkb:A8K4S6|uniprotkb:D3DNM2 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:ima3_human(display_long)|uniprotkb:KPNA4(gene name)|psi-mi:KPNA4(display_short)|uniprotkb:QIP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-4(gene name synonym)|uniprotkb:Importin alpha Q1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_002259.1|ensembl:ENSG00000186432(gene)|ensembl:ENST00000334256(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00629|rcsb pdb:4UAE|rcsb pdb:5TBK|rcsb pdb:5XZX|rcsb pdb:6BVV|rcsb pdb:6BVZ|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|rcsb pdb:6WX8|rcsb pdb:7JJL|reactome:R-HSA-1169408|reactome:R-HSA-168276|ensembl:ENSP00000334373|dip:DIP-32982N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:/cng/xZ42E2juzHNOpuQTP+amx89606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:Q99880 intact:EBI-6151657 intact:EBI-1237119|uniprotkb:Q52LW9|uniprotkb:B2R5A3|ensembl:ENSP00000366618 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2b1l_human(display_long)|uniprotkb:H2BC13(gene name)|psi-mi:H2BC13(display_short)|uniprotkb:H2BFC(gene name synonym)|uniprotkb:HIST1H2BL(gene name synonym)|uniprotkb:Histone H2B.c(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_003510.1|dip:DIP-38154N|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|ensembl:ENSG00000185130(gene)|ensembl:ENST00000377401(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|interpro:IPR009072(Histone-fold)|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5250924|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:vVD3xoHavMKCopzEez7zarZBKFc9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P07737 intact:EBI-6151657 intact:EBI-713780|ensembl:ENSP00000225655|uniprotkb:Q53Y44 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:prof1_human(display_long)|uniprotkb:Profilin I(gene name synonym)|uniprotkb:PFN1(gene name)|psi-mi:PFN1(display_short)|uniprotkb:Epididymis tissue protein Li 184a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 ensembl:ENSG00000108518(gene)|ensembl:ENST00000225655(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060074"(synapse maturation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0072562"(blood microparticle)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900029"(positive regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR029892|interpro:IPR036140|mint:P07737|rcsb pdb:1AWI|rcsb pdb:1CF0|rcsb pdb:1CJF|rcsb pdb:1FIK|rcsb pdb:1FIL|rcsb pdb:1PFL|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|rcsb pdb:4X1L|rcsb pdb:4X1M|rcsb pdb:4X25|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6NBW|reactome:R-HSA-114608|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|reactome:R-HSA-4086400|reactome:R-HSA-5663220|reactome:R-HSA-376176|refseq:NP_005013.1|dip:DIP-30N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:CncaC5RMylvzFLhqzpS+VbhQn6I9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P62807 intact:EBI-6151657 intact:EBI-354552|uniprotkb:Q4VB69|uniprotkb:P02278|uniprotkb:Q3B872|uniprotkb:Q93078|uniprotkb:Q93080|ensembl:ENSP00000321744|ensembl:ENSP00000348924|ensembl:ENSP00000366962|ensembl:ENSP00000380180|ensembl:ENSP00000445633|ensembl:ENSP00000483237|ensembl:ENSP00000489317 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2b1c_human(display_long)|uniprotkb:HIST1H2BG(gene name synonym)|uniprotkb:HIST1H2BI(gene name synonym)|uniprotkb:Histone H2B.1 A(gene name synonym)|uniprotkb:Histone H2B.a(gene name synonym)|uniprotkb:Histone H2B.g(gene name synonym)|uniprotkb:Histone H2B.h(gene name synonym)|uniprotkb:Histone H2B.k(gene name synonym)|uniprotkb:Histone H2B.l(gene name synonym)|uniprotkb:H2BC10(gene name)|psi-mi:H2BC10(display_short)|uniprotkb:H2BC4(gene name)|psi-mi:H2BC4(display_short)|uniprotkb:H2BC6(gene name)|psi-mi:H2BC6(display_short)|uniprotkb:H2BC7(gene name)|psi-mi:H2BC7(display_short)|uniprotkb:H2BC8(gene name)|psi-mi:H2BC8(display_short)|uniprotkb:H2BFA(gene name synonym)|uniprotkb:H2BFG(gene name synonym)|uniprotkb:H2BFH(gene name synonym)|uniprotkb:H2BFK(gene name synonym)|uniprotkb:H2BFL(gene name synonym)|uniprotkb:HIST1H2BC(gene name synonym)|uniprotkb:HIST1H2BE(gene name synonym)|uniprotkb:HIST1H2BF(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_003509.1|refseq:NP_003513.1|refseq:NP_003514.2|refseq:NP_003516.1|refseq:NP_003517.2|refseq:NP_066407.1|rcsb pdb:7A08|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|rcsb pdb:6XJD|ensembl:ENSG00000180596(gene)|ensembl:ENSG00000273802(gene)|ensembl:ENSG00000274290(gene)|ensembl:ENSG00000277224(gene)|ensembl:ENSG00000278588(gene)|ensembl:ENST00000314332(transcript)|ensembl:ENST00000356530(transcript)|ensembl:ENST00000377733(transcript)|ensembl:ENST00000396984(transcript)|ensembl:ENST00000541790(transcript)|ensembl:ENST00000614097(transcript)|ensembl:ENST00000634910(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0042802"(identical protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P62807|rcsb pdb:5GT0|rcsb pdb:5KGF|rcsb pdb:6ACO|rcsb pdb:6C0W|rcsb pdb:6FML|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6X59|rcsb pdb:6X5A|dip:DIP-32890N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:00sapwbWn8dtUr7qoPsRPUlL35A9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:Q14974 intact:EBI-6151657 intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P12277 intact:EBI-6151657 intact:EBI-357706|uniprotkb:Q2LE07|uniprotkb:A8K236|uniprotkb:B2R5R4|uniprotkb:Q6FG40|uniprotkb:Q9UC66|ensembl:ENSP00000299198 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:kcrb_human(display_long)|uniprotkb:CKB(gene name)|psi-mi:CKB(display_short)|uniprotkb:CKBB(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:Brain creatine kinase(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_001814.2|go:"GO:0005829"(cytosol)|ensembl:ENSG00000166165(gene)|ensembl:ENST00000348956(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12277|rcsb pdb:3B6R|rcsb pdb:3DRB|rcsb pdb:3DRE|rcsb pdb:6V9H|go:"GO:0021762"(substantia nigra development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|reactome:R-HSA-71288|reactome:R-HSA-9696264|dip:DIP-52968N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:WLRnU8sRUfJQoaPY0edGi9xiR+g9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P08311 intact:EBI-6151657 intact:EBI-5462635|uniprotkb:Q6IBJ6|uniprotkb:Q9UCA5|uniprotkb:Q9UCU6|ensembl:ENSP00000216336 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:catg_human(display_long)|uniprotkb:CTSG(gene name)|psi-mi:CTSG(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_001902.1|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030141"(secretory granule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035590"(purinergic nucleotide receptor signaling pathway)|ensembl:ENSG00000100448(gene)|ensembl:ENST00000216336(transcript)|go:"GO:0002003"(angiotensin maturation)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006508"(proteolysis)|go:"GO:0006955"(immune response)|go:"GO:0008201"(heparin binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0009986"(cell surface)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0050778"(positive regulation of immune response)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070946"(neutrophil-mediated killing of gram-positive bacterium)|go:"GO:0071222"(cellular response to lipopolysaccharide)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:P08311|rcsb pdb:1AU8|reactome:R-HSA-448706|rcsb pdb:1CGH|rcsb pdb:1KYN|rcsb pdb:1T32|rcsb pdb:6VTM|reactome:R-HSA-6798695|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-2022377|reactome:R-HSA-381426|reactome:R-HSA-6803157|reactome:R-HSA-9635465|reactome:R-HSA-9660826 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:Q3qTg9KcvP4oI+A/QOUqk7ahWMU9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P62258 intact:EBI-6151657 intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:Q99879 intact:EBI-6151657 intact:EBI-3893474|uniprotkb:Q6NWQ3|ensembl:ENSP00000477907 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2b1m_human(display_long)|uniprotkb:H2BC14(gene name)|psi-mi:H2BC14(display_short)|uniprotkb:H2BFE(gene name synonym)|uniprotkb:HIST1H2BM(gene name synonym)|uniprotkb:Histone H2B.e(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_003512.1|ensembl:ENSG00000273703(gene)|ensembl:ENST00000621112(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-912446|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:ETy0Ge+X/+GWAlBGq+YpQLc+DoE9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P61626 intact:EBI-6151657 intact:EBI-355360|ensembl:ENSP00000261267|uniprotkb:P00695|uniprotkb:Q9UCF8|uniprotkb:Q13170 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:lysc_human(display_long)|uniprotkb:LYZ(gene name)|psi-mi:LYZ(display_short)|uniprotkb:LZM(gene name synonym)|uniprotkb:1,4-beta-N-acetylmuramidase C(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 ensembl:ENSG00000090382(gene)|refseq:NP_000230.1|rcsb pdb:1GB7|rcsb pdb:1GB8|rcsb pdb:1GB9|rcsb pdb:1GBO|rcsb pdb:1GBW|rcsb pdb:1GBX|rcsb pdb:1GBY|rcsb pdb:1GBZ|rcsb pdb:1GDW|rcsb pdb:1GDX|rcsb pdb:1GE0|rcsb pdb:1GE1|rcsb pdb:1GE2|rcsb pdb:1GE3|rcsb pdb:1GE4|rcsb pdb:1GEV|rcsb pdb:1GEZ|rcsb pdb:1GF0|rcsb pdb:1GF3|rcsb pdb:1GF4|rcsb pdb:1GF5|rcsb pdb:1GF6|rcsb pdb:1GF7|rcsb pdb:1GF8|rcsb pdb:1GF9|rcsb pdb:1GFA|rcsb pdb:1GFE|rcsb pdb:1GFG|rcsb pdb:1GFH|rcsb pdb:1GFJ|rcsb pdb:1GFK|rcsb pdb:1GFR|rcsb pdb:1GFT|rcsb pdb:1GFU|rcsb pdb:1GFV|rcsb pdb:1HNL|rcsb pdb:1I1Z|rcsb pdb:1I20|rcsb pdb:1I22|rcsb pdb:1INU|rcsb pdb:1IOC|rcsb pdb:1IP1|rcsb pdb:1IP2|rcsb pdb:1IP3|rcsb pdb:1IP4|rcsb pdb:1IP5|rcsb pdb:1IP6|rcsb pdb:1IP7|rcsb pdb:1IWT|rcsb pdb:1IWU|rcsb pdb:1IWV|rcsb pdb:1IWW|rcsb pdb:1IWX|rcsb pdb:1IWY|rcsb pdb:1IWZ|rcsb pdb:1IX0|rcsb pdb:1IY3|rcsb pdb:1IY4|rcsb pdb:1JKA|rcsb pdb:1JKB|rcsb pdb:1JKC|rcsb pdb:1JKD|rcsb pdb:1JSF|rcsb pdb:1JWR|rcsb pdb:1LAA|rcsb pdb:1LHH|rcsb pdb:1LHI|rcsb pdb:1LHJ|rcsb pdb:1LHK|rcsb pdb:1LHL|rcsb pdb:1LHM|rcsb pdb:1LMT|rcsb pdb:1LOZ|rcsb pdb:1LYY|rcsb pdb:1LZ1|rcsb pdb:1LZ4|rcsb pdb:1LZ5|rcsb pdb:1LZ6|rcsb pdb:1LZR|rcsb pdb:1LZS|rcsb pdb:1OP9|rcsb pdb:1OUA|rcsb pdb:1OUB|rcsb pdb:1OUC|rcsb pdb:1OUD|rcsb pdb:1OUE|rcsb pdb:1OUF|rcsb pdb:1OUG|rcsb pdb:1OUH|rcsb pdb:1OUI|rcsb pdb:1OUJ|rcsb pdb:1QSW|rcsb pdb:1RE2|rcsb pdb:1REM|rcsb pdb:1REX|rcsb pdb:1REY|rcsb pdb:1REZ|rcsb pdb:1TAY|rcsb pdb:1TBY|rcsb pdb:1TCY|rcsb pdb:1TDY|rcsb pdb:1UBZ|rcsb pdb:5LVK|rcsb pdb:6LFH|reactome:R-HSA-6798695|reactome:R-HSA-6803157|reactome:R-HSA-977225|rcsb pdb:1W08|rcsb pdb:1WQM|rcsb pdb:1WQN|rcsb pdb:1WQO|rcsb pdb:1WQP|rcsb pdb:1WQQ|rcsb pdb:1WQR|rcsb pdb:1YAM|rcsb pdb:1YAN|rcsb pdb:1YAO|rcsb pdb:1YAP|rcsb pdb:1YAQ|rcsb pdb:207L|rcsb pdb:208L|rcsb pdb:2BQA|rcsb pdb:2BQB|rcsb pdb:2BQC|rcsb pdb:2BQD|rcsb pdb:2BQE|rcsb pdb:2BQF|rcsb pdb:2BQG|rcsb pdb:2BQH|rcsb pdb:2BQI|rcsb pdb:2BQJ|rcsb pdb:2BQK|rcsb pdb:2BQL|rcsb pdb:2BQM|rcsb pdb:2BQN|rcsb pdb:2BQO|rcsb pdb:2HEA|rcsb pdb:2HEB|rcsb pdb:2HEC|rcsb pdb:2HED|rcsb pdb:2HEE|rcsb pdb:2HEF|rcsb pdb:2LHM|rcsb pdb:2MEA|rcsb pdb:2MEB|rcsb pdb:2MEC|rcsb pdb:2MED|rcsb pdb:2MEE|rcsb pdb:2MEF|rcsb pdb:2MEG|rcsb pdb:2MEH|rcsb pdb:2MEI|rcsb pdb:2NWD|rcsb pdb:2ZIJ|rcsb pdb:2ZIK|rcsb pdb:2ZIL|rcsb pdb:2ZWB|rcsb pdb:3EBA|rcsb pdb:3FE0|rcsb pdb:3LHM|rcsb pdb:3LN2|rcsb pdb:4I0C|rcsb pdb:4ML7|rcsb pdb:4R0P|rcsb pdb:5LSH|rcsb pdb:1B5X|rcsb pdb:1B5Y|rcsb pdb:1B5Z|rcsb pdb:1B7L|rcsb pdb:1B7M|rcsb pdb:1B7N|rcsb pdb:1B7O|rcsb pdb:1B7P|rcsb pdb:1B7Q|rcsb pdb:1B7R|rcsb pdb:1B7S|rcsb pdb:1BB3|rcsb pdb:1BB4|rcsb pdb:1BB5|rcsb pdb:1C43|rcsb pdb:1C45|rcsb pdb:1C46|rcsb pdb:1C7P|rcsb pdb:1CJ6|rcsb pdb:1CJ7|rcsb pdb:1CJ8|ensembl:ENST00000261267(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003796"(lysozyme activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0008152"(metabolic process)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0019835"(cytolysis)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR000974(Glycoside hydrolase, family 22, lysozyme)|interpro:IPR001916(Glycoside hydrolase, family 22)|interpro:IPR019799|interpro:IPR023346|interpro:IPR030056|mint:P61626|rcsb pdb:133L|rcsb pdb:134L|rcsb pdb:1B5U|rcsb pdb:1B5V|rcsb pdb:1B5W|rcsb pdb:1CJ9|rcsb pdb:1CKC|rcsb pdb:1CKD|rcsb pdb:1CKF|rcsb pdb:1CKG|rcsb pdb:1CKH|rcsb pdb:1D6P|rcsb pdb:1D6Q|rcsb pdb:1DI3|rcsb pdb:1DI4|rcsb pdb:1DI5|rcsb pdb:1EQ4|rcsb pdb:1EQ5|rcsb pdb:1EQE|rcsb pdb:1GAY|rcsb pdb:1GAZ|rcsb pdb:1GB0|rcsb pdb:1GB2|rcsb pdb:1GB3|rcsb pdb:1GB5|rcsb pdb:1GB6 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:jydNN9yuU9EYvnth+kv115svRxw9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P08246 intact:EBI-6151657 intact:EBI-986345|uniprotkb:P09649|uniprotkb:Q6B0D9|uniprotkb:Q6LDP5|ensembl:ENSP00000263621|ensembl:ENSP00000466090|ensembl:ENSP00000480128|ensembl:ENSP00000488075 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:elne_human(display_long)|uniprotkb:Elastase-2(gene name synonym)|uniprotkb:ELANE(gene name)|psi-mi:ELANE(display_short)|uniprotkb:PMN elastase(gene name synonym)|uniprotkb:Bone marrow serine protease(gene name synonym)|uniprotkb:Medullasin(gene name synonym)|uniprotkb:Human leukocyte elastase(gene name synonym)|uniprotkb:ELA2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 ensembl:ENSG00000197561(gene)|ensembl:ENSG00000277571(gene)|ensembl:ENST00000263621(transcript)|ensembl:ENST00000590230(transcript)|ensembl:ENST00000615489(transcript)|ensembl:ENST00000632488(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001878"(response to yeast)|go:"GO:0002020"(protease binding)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002812"(biosynthetic process of antibacterial peptides active against Gram-negative bacteria)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006909"(phagocytosis)|go:"GO:0008201"(heparin binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0009411"(response to UV)|go:"GO:0009986"(cell surface)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019955"(cytokine binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030141"(secretory granule)|go:"GO:0030163"(protein catabolic process)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050778"(positive regulation of immune response)|go:"GO:0050922"(negative regulation of chemotaxis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070269"(pyroptosis)|go:"GO:0070945"(neutrophil-mediated killing of gram-negative bacterium)|go:"GO:0070947"(neutrophil-mediated killing of fungus)|go:"GO:1903238"(positive regulation of leukocyte tethering or rolling)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:P08246|rcsb pdb:1B0F|rcsb pdb:1H1B|rcsb pdb:1HNE|rcsb pdb:1PPF|rcsb pdb:1PPG|rcsb pdb:2RG3|rcsb pdb:2Z7F|rcsb pdb:3Q76|rcsb pdb:3Q77|rcsb pdb:4NZL|rcsb pdb:4WVP|rcsb pdb:5A09|rcsb pdb:5A0A|rcsb pdb:5A0B|rcsb pdb:5A0C|rcsb pdb:5A8X|rcsb pdb:5A8Y|rcsb pdb:5A8Z|rcsb pdb:5ABW|rcsb pdb:6E69|rcsb pdb:6F5M|rcsb pdb:6SMA|rcsb pdb:7CBK|reactome:R-HSA-1442490|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-5620971|reactome:R-HSA-6798695|reactome:R-HSA-6803157|reactome:R-HSA-977606|refseq:NP_001963.1|refseq:XP_011526078.1|refseq:XP_011526077.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:0XCflWhF346d7Dy2+ENeMyDHPmA9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P42224 intact:EBI-6151657 intact:EBI-1057697|uniprotkb:Q53S88|uniprotkb:Q53XW4|uniprotkb:B2RCA0|uniprotkb:Q9UDL5|uniprotkb:A8K989|uniprotkb:D2KFR8|uniprotkb:Q68D00|uniprotkb:D3DPI7|ensembl:ENSP00000354394|ensembl:ENSP00000386244|ensembl:ENSP00000388240|ensembl:ENSP00000438703 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:stat1_human(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)|uniprotkb:Transcription factor ISGF-3 components p91/p84(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_009330.1|refseq:NP_644671.1|rcsb pdb:1YVL|rcsb pdb:2KA6|rcsb pdb:3WWT|reactome:R-HSA-1059683|reactome:R-HSA-1169408|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8939902|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9013508|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-909733|rcsb pdb:1BF5|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-912694|refseq:XP_006712781.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016922"(nuclear receptor binding)|ensembl:ENSG00000115415(gene)|ensembl:ENST00000361099(transcript)|ensembl:ENST00000409465(transcript)|ensembl:ENST00000415035(transcript)|ensembl:ENST00000540176(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051607"(defense response to virus)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0061326"(renal tubule development)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022752|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|interpro:IPR035859|interpro:IPR036535|interpro:IPR036860|interpro:IPR038295|mint:P42224|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042393"(histone binding)|dip:DIP-46140N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:a2ZnhdFZkctbjaXLpsYNJ3q5Cv49606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P58876 intact:EBI-6151657 intact:EBI-4409942|ensembl:ENSP00000289316|ensembl:ENSP00000367008 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2b1d_human(display_long)|uniprotkb:Histone H2B.b(gene name synonym)|uniprotkb:H2BC5(gene name)|psi-mi:H2BC5(display_short)|uniprotkb:H2B-clustered histone 5(gene name synonym)|uniprotkb:H2BFB(gene name synonym)|uniprotkb:HIRA-interacting protein 2(gene name synonym)|uniprotkb:HIRIP2(gene name synonym)|uniprotkb:HIST1H2BD(gene name synonym)|uniprotkb:Histone H2B.1 B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_066407.1|refseq:NP_619790.1|ensembl:ENSG00000158373(gene)|ensembl:ENST00000289316(transcript)|ensembl:ENST00000377777(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P58876|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005634"(nucleus) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:07VBw5MCphdkMydMOPSjVqpGriI9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P0C0S8 intact:EBI-6151657 intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:Q96KK5 intact:EBI-6151657 intact:EBI-6147668|ensembl:ENSP00000366679 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a1h_human(display_long)|uniprotkb:H2AC12(gene name)|psi-mi:H2AC12(display_short)|uniprotkb:H2A-clustered histone 12(gene name synonym)|uniprotkb:HIST1H2AH(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:Histone H2A/s(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_542163.1|dip:DIP-61699N|ensembl:ENSG00000274997(gene)|ensembl:ENST00000377459(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:Oa322n+evy8Cu0E9cWTEdYwQPKM9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P0CG05 intact:EBI-6151657 intact:EBI-6151637|uniprotkb:P80423|uniprotkb:A0M8Q4|uniprotkb:P0DOY2|uniprotkb:A0A075B6K9 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:iglc2_human(display_long)|uniprotkb:IGLC2(gene name)|psi-mi:IGLC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-2029481|reactome:R-HSA-2029482|go:"GO:0004252"(serine-type endopeptidase activity)|rcsb pdb:5IQ7|rcsb pdb:5IQ9|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|rcsb pdb:4LLQ|rcsb pdb:4O58|rcsb pdb:4O5I|go:"GO:0003823"(antigen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0045087"(innate immune response)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|rcsb pdb:1JVK|rcsb pdb:1LIL|rcsb pdb:1ZVO|rcsb pdb:2JB5|rcsb pdb:2JB6|rcsb pdb:3C2A|rcsb pdb:3TV3|rcsb pdb:3TWC|rcsb pdb:3TYG|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:4LLD|rcsb pdb:4LLM|rcsb pdb:4EOW|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-2871837|reactome:R-HSA-983695|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006956"(complement activation)|go:"GO:0050776"(regulation of immune response)|rcsb pdb:4LLU|rcsb pdb:4LLW|rcsb pdb:4LLY|reactome:R-HSA-5690714|rcsb pdb:6DE7|ensembl:ENST00000390323|ensembl:ENSP00000374856|ensembl:ENSG00000211677|reactome:R-HSA-202733|reactome:R-HSA-977606|go:"GO:0050900"(leukocyte migration)|go:"GO:0030449"(regulation of complement activation)|interpro:IPR036179 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:Nu+YqoiJBEpFp8ZpCoVts4PgqZM9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P05164 intact:EBI-6151657 intact:EBI-2556173|uniprotkb:Q14862|uniprotkb:Q9UCL7|uniprotkb:A1L4B8|uniprotkb:Q4PJH5|ensembl:ENSP00000225275 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:perm_human(display_long)|uniprotkb:MPO(gene name)|psi-mi:MPO(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_000241.1|ensembl:ENSG00000005381(gene)|go:"GO:0002149"(hypochlorous acid biosynthetic process)|go:"GO:0002679"(respiratory burst involved in defense response)|go:"GO:0003682"(chromatin binding)|ensembl:ENST00000225275(transcript)|go:"GO:0001878"(response to yeast)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0006952"(defense response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007568"(aging)|go:"GO:0008201"(heparin binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0020037"(heme binding)|go:"GO:0030141"(secretory granule)|go:"GO:0032094"(response to food)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042582"(azurophil granule)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1990268"(response to gold nanoparticle)|interpro:IPR010255(Haem peroxidase)|interpro:IPR019791|interpro:IPR029609|interpro:IPR037120|mint:P05164|rcsb pdb:1CXP|rcsb pdb:1D2V|rcsb pdb:1D5L|rcsb pdb:1D7W|rcsb pdb:1DNU|rcsb pdb:1DNW|rcsb pdb:1MHL|rcsb pdb:1MYP|rcsb pdb:3F9P|rcsb pdb:3ZS0|rcsb pdb:3ZS1|rcsb pdb:4C1M|rcsb pdb:4DL1|rcsb pdb:4EJX|rcsb pdb:5FIW|rcsb pdb:5MFA|rcsb pdb:5UZU|rcsb pdb:6AZP|rcsb pdb:6BMT|reactome:R-HSA-6798695|reactome:R-HSA-8941413 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:SNoAXb3csr/iOyGWeyWcUyJTZLY9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P02788 intact:EBI-6151657 intact:EBI-1058602|ensembl:ENSP00000231751|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|uniprotkb:A8K9U8 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_001308050.1|ensembl:ENST00000231751(transcript)|go:"GO:0001503"(ossification)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006826"(iron ion transport)|go:"GO:0006959"(humoral immune response)|go:"GO:0008201"(heparin binding)|ensembl:ENSG00000012223(gene)|refseq:NP_001186078.1|refseq:NP_002334.2|go:"GO:0009986"(cell surface)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0030141"(secretory granule)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035580"(specific granule lumen)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1900159"(positive regulation of bone mineralization involved in bone maturation)|go:"GO:1900229"(negative regulation of single-species biofilm formation in or on host organism)|go:"GO:0042581"(specific granule)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:2000117"(negative regulation of cysteine-type endopeptidase activity)|go:"GO:2000308"("negative regulation of tumor necrosis factor (ligand) superfamily member 11 production")|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:2001205"(negative regulation of osteoclast development)|go:"GO:0044793"(negative regulation by host of viral process)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|go:"GO:0045837"(negative regulation of membrane potential)|go:"GO:0048525"(negative regulation of viral process)|interpro:IPR016357(Transferrin)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051673"(membrane disruption in another organism)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1H45|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|rcsb pdb:1U62|refseq:NP_001308051.1|dip:DIP-41354N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P04908 intact:EBI-6151657 intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:4Qno1mMYZB6FdNoojrzulWLVq849606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P24158 intact:EBI-6151657 intact:EBI-465028|uniprotkb:Q9UQD8|ensembl:ENSP00000234347|ensembl:ENSP00000478977|uniprotkb:P15637|uniprotkb:P18078|uniprotkb:Q4VB09|uniprotkb:Q6LBM7|uniprotkb:Q4VB08|uniprotkb:Q6LBN2|uniprotkb:Q9UD25 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:prtn3_human(display_long)|uniprotkb:MBN(gene name synonym)|uniprotkb:PRTN3(gene name)|psi-mi:PRTN3(display_short)|uniprotkb:Leukocyte proteinase 3(gene name synonym)|uniprotkb:AGP7(gene name synonym)|uniprotkb:Wegener autoantigen(gene name synonym)|uniprotkb:P29(gene name synonym)|uniprotkb:C-ANCA antigen(gene name synonym)|uniprotkb:Neutrophil proteinase 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 ensembl:ENSG00000196415(gene)|ensembl:ENSG00000277804(gene)|ensembl:ENST00000234347(transcript)|ensembl:ENST00000612112(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006909"(phagocytosis)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0019899"(enzyme binding)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045217"(cell-cell junction maintenance)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072672"(neutrophil extravasation)|go:"GO:0097029"(mature conventional dendritic cell differentiation)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:P24158|rcsb pdb:1FUJ|reactome:R-HSA-140875|reactome:R-HSA-449836|reactome:R-HSA-6798695|reactome:R-HSA-6803157|interpro:IPR001314(Peptidase S1A, chymotrypsin)|refseq:NP_002768.3|dip:DIP-31107N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:+28oFrY+yAY4MtIR0vfAfItyhrM9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:Q93077 intact:EBI-6151657 intact:EBI-725259|uniprotkb:O00775|uniprotkb:O00776|uniprotkb:O00777|uniprotkb:O00778|uniprotkb:Q540R1|uniprotkb:B2R4F7|ensembl:ENSP00000321389|ensembl:ENSP00000367022|ensembl:ENSP00000473534 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2a1c_human(display_long)|uniprotkb:H2AC6(gene name)|psi-mi:H2AC6(display_short)|uniprotkb:H2A-clustered histone 6(gene name synonym)|uniprotkb:H2AFL(gene name synonym)|uniprotkb:HIST1H2AC(gene name synonym)|uniprotkb:Histone H2A/l(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_003503.1|ensembl:ENSG00000180573(gene)|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENST00000314088(transcript)|ensembl:ENST00000377791(transcript)|ensembl:ENST00000602637(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|rcsb pdb:6C0W|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:7A08|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|interpro:IPR032458 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:m00IdooZksbNGKHSsaVvGFVpcko9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:O00505 intact:EBI-6151657 intact:EBI-358297|intact:EBI-28976892|ensembl:ENSP00000261667|uniprotkb:O00191|uniprotkb:O43195|uniprotkb:Q96AA7|uniprotkb:Q5JVM9|intact:EBI-742146|uniprotkb:Q8IYQ9 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:ima4_human(display_long)|uniprotkb:KPNA3(gene name)|psi-mi:KPNA3(display_short)|uniprotkb:QIP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym)|uniprotkb:SRP1-gamma(gene name synonym)|uniprotkb:Importin alpha Q2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 ensembl:ENSG00000102753(gene)|ensembl:ENST00000261667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043657"(host cell)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000225(Armadillo)|refseq:NP_002258.2|ensembl:ENSP00000261667|dip:DIP-27586N|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00505|reactome:R-HSA-1169408|reactome:R-HSA-168276 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:kx/oTYWMYG7dhwJHvr1POLD6FTU9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:Q99877 intact:EBI-6151657 intact:EBI-744423|uniprotkb:Q494S8|uniprotkb:Q96FB7|uniprotkb:B2R5L4|ensembl:ENSP00000446031|ensembl:ENSP00000483903 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2b1n_human(display_long)|uniprotkb:H2BC15(gene name)|psi-mi:H2BC15(display_short)|uniprotkb:H2BFD(gene name synonym)|uniprotkb:HIST1H2BN(gene name synonym)|uniprotkb:Histone H2B.d(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_003511.1|ensembl:ENSG00000233822(gene)|ensembl:ENST00000449538(transcript)|ensembl:ENST00000612898(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:nGZETothwO57PuE11M5ogikaZkM9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P01876 intact:EBI-6151657 intact:EBI-727651|ensembl:ENSP00000374989|ensembl:ENSP00000488021 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:igha1_human(display_long)|uniprotkb:IGHA1(gene name)|psi-mi:IGHA1(display_short)|uniprotkb:Ig alpha-1 chain C region(gene name synonym)|uniprotkb:Ig alpha-1 chain C region BUR(gene name synonym)|uniprotkb:Ig alpha-1 chain C region TRO(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 ensembl:ENSG00000211895(gene)|ensembl:ENSG00000282633(gene)|ensembl:ENST00000390547(transcript)|ensembl:ENST00000633714(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003094"(glomerular filtration)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0060267"(positive regulation of respiratory burst)|go:"GO:0071748"(monomeric IgA immunoglobulin complex)|go:"GO:0071751"(secretory IgA immunoglobulin complex)|go:"GO:0071752"(secretory dimeric IgA immunoglobulin complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1IGA|rcsb pdb:1OW0|rcsb pdb:2ESG|rcsb pdb:2QEJ|rcsb pdb:3CHN|rcsb pdb:6LX3|rcsb pdb:6LXW|rcsb pdb:6UE7|rcsb pdb:6XJA|reactome:R-HSA-202733|reactome:R-HSA-2168880|go:"GO:0070062"(extracellular exosome) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:Mystbtg9uttxFXl//LGdoM32po09606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:Q9BTM1 intact:EBI-6151657 intact:EBI-4398590|uniprotkb:Q9NV63|ensembl:ENSP00000373730|ensembl:ENSP00000438553 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2aj_human(display_long)|uniprotkb:H2AJ(gene name)|psi-mi:H2AJ(display_short)|uniprotkb:H2AFJ(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_808760.1|ensembl:ENSG00000246705(gene)|ensembl:ENST00000389078(transcript)|ensembl:ENST00000544848(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:4EDU|rcsb pdb:6K60|rcsb pdb:6KVD|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-8939236 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:g6br63FeM17yJRfQI3GnmoM0vbc9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P61981 intact:EBI-6151657 intact:EBI-359832|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q6FH52|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSP00000306330 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:1433g_human(display_long)|uniprotkb:YWHAG(gene name)|psi-mi:YWHAG(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_036611.2|ensembl:ENSG00000170027(gene)|ensembl:ENST00000307630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006605"(protein targeting)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61981|rcsb pdb:2B05|rcsb pdb:3UZD|rcsb pdb:4E2E|rcsb pdb:4J6S|rcsb pdb:4O46|rcsb pdb:5D3E|rcsb pdb:6A5S|rcsb pdb:6BYJ|rcsb pdb:6BYL|rcsb pdb:6BZD|rcsb pdb:6FEL|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y4K|rcsb pdb:6Y6B|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-9614399|dip:DIP-33406N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:u1cd71h0RPgTOEMrQVhOelsxWnM9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:Q5QNW6 intact:EBI-6151657 intact:EBI-6147754|uniprotkb:B4DLA9|uniprotkb:A8K0U9|ensembl:ENSP00000358164 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h2b2f_human(display_long)|uniprotkb:H2BC18(gene name)|psi-mi:H2BC18(display_short)|uniprotkb:H2B-clustered histone 18(gene name synonym)|uniprotkb:HIST2H2BF(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_001019770.1|refseq:NP_001154806.1|ensembl:ENSG00000203814(gene)|ensembl:ENST00000369167(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q5QNW6|rcsb pdb:6MUO|rcsb pdb:6MUP|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-5689880|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:Pr400UVIaD7O446lc9vZeStUKn09606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P62805 intact:EBI-6151657 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P04083 intact:EBI-6151657 intact:EBI-354007|ensembl:ENSP00000257497|ensembl:ENSP00000366109|uniprotkb:B5BU38 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:anxa1_human(display_long)|uniprotkb:ANXA1(gene name)|psi-mi:ANXA1(display_short)|uniprotkb:ANX1(gene name synonym)|uniprotkb:LPC1(gene name synonym)|uniprotkb:Annexin-1(gene name synonym)|uniprotkb:Annexin I(gene name synonym)|uniprotkb:Lipocortin I(gene name synonym)|uniprotkb:Calpactin II(gene name synonym)|uniprotkb:Chromobindin-9(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Phospholipase A2 inhibitory protein(gene name synonym)|uniprotkb:Calpactin-2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_000691.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030073"(insulin secretion)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030850"(prostate gland development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0031514"(motile cilium)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032652"(regulation of interleukin-1 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033031"(positive regulation of neutrophil apoptotic process)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0042063"(gliogenesis)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042493"|go:"GO:0042629"(mast cell granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045087"(innate immune response)|go:"GO:0045627"(positive regulation of T-helper 1 cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045920"(negative regulation of exocytosis)|go:"GO:0046632"(alpha-beta T cell differentiation)|ensembl:ENSG00000135046(gene)|ensembl:ENST00000257497(transcript)|ensembl:ENST00000376911(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001780"(neutrophil homeostasis)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010165"(response to X-ray)|go:"GO:0014839"(myoblast migration involved in skeletal muscle regeneration)|go:"GO:0016323"(basolateral plasma membrane)|refseq:XP_011516911.1|dip:DIP-32875N|go:"GO:0046883"(regulation of hormone secretion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070459"(prolactin secretion)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071621"(granulocyte chemotaxis)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900138"(negative regulation of phospholipase A2 activity)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001464(Annexin)|interpro:IPR002388(Annexin, type I)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P04083|rcsb pdb:1AIN|rcsb pdb:1BO9|rcsb pdb:1QLS|rcsb pdb:5VFW|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-444473|reactome:R-HSA-445355|reactome:R-HSA-6785807|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050727"(regulation of inflammatory response) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:QKmqz+UsAof35B/so2qKLQjn2v09606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P12273 intact:EBI-6151657 intact:EBI-1049746|uniprotkb:A0A963|uniprotkb:A0A9C3|uniprotkb:A0A9F3|uniprotkb:A4D2I1|ensembl:ENSP00000291009 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:pip_human(display_long)|uniprotkb:Prolactin-induced protein(gene name synonym)|uniprotkb:Secretory actin-binding protein(gene name synonym)|uniprotkb:Gross cystic disease fluid protein 15(gene name synonym)|uniprotkb:gp17(gene name synonym)|uniprotkb:PIP(gene name)|psi-mi:PIP(display_short)|uniprotkb:GCDFP15(gene name synonym)|uniprotkb:GPIP4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_002643.1|ensembl:ENSG00000159763(gene)|ensembl:ENST00000291009(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0003779"(actin binding)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006508"(proteolysis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019864"(IgG binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|interpro:IPR007990(Seminal vesicle autoantigen)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|mint:P12273|rcsb pdb:3ES6|reactome:R-HSA-5223345|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:/OC16zeRzFp520uPPLHh+WekPPc9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P31946 intact:EBI-6151657 intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C1C6 uniprotkb:P01857 intact:EBI-6151657 intact:EBI-356114|ensembl:ENSP00000374991|ensembl:ENSP00000488387 psi-mi:w_hendh(display_long)|uniprotkb:P/V/C(gene name)|psi-mi:P/V/C(display_short) psi-mi:ighg1_human(display_long)|uniprotkb:IGHG1(gene name)|psi-mi:IGHG1(display_short)|uniprotkb:Ig gamma-1 chain C region(gene name synonym)|uniprotkb:Ig gamma-1 chain C region EU(gene name synonym)|uniprotkb:Ig gamma-1 chain C region KOL(gene name synonym)|uniprotkb:Ig gamma-1 chain C region NIE(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:928303(hendh)|taxid:928303("Hendra virus (isolate Horse/Autralia/Hendra/1994)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158469|imex:IM-17331-54 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6BW1|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|interpro:IPR025909|interpro:IPR035430 ensembl:ENSG00000211896(gene)|ensembl:ENSG00000277633(gene)|ensembl:ENST00000390549(transcript)|ensembl:ENST00000631466(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P01857|rcsb pdb:1AJ7|rcsb pdb:1AQK|rcsb pdb:1AXS|rcsb pdb:1BEY|rcsb pdb:1D5B|rcsb pdb:1D5I|rcsb pdb:1D6V|rcsb pdb:1DFB|rcsb pdb:1DN2|rcsb pdb:1E4K|rcsb pdb:1FC1|rcsb pdb:1FC2|rcsb pdb:1FCC|rcsb pdb:1GAF|rcsb pdb:1H3T|rcsb pdb:1H3U|rcsb pdb:1H3V|rcsb pdb:1H3W|rcsb pdb:1H3X|rcsb pdb:1H3Y|rcsb pdb:1HKL|rcsb pdb:1HZH|rcsb pdb:1L6X|rcsb pdb:1N7M|rcsb pdb:1OQO|rcsb pdb:1OQX|rcsb pdb:1PG7|rcsb pdb:1T83|rcsb pdb:1T89|rcsb pdb:1VGE|rcsb pdb:2DTS|rcsb pdb:2GJ7|rcsb pdb:2I5Y|rcsb pdb:2IWG|rcsb pdb:2J6E|rcsb pdb:2JB5|rcsb pdb:2JB6|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2OSL|rcsb pdb:2QAD|rcsb pdb:2QL1|rcsb pdb:2QQK|rcsb pdb:2QQL|rcsb pdb:2QQN|rcsb pdb:2QR0|rcsb pdb:2R56|rcsb pdb:2RCS|rcsb pdb:2VXQ|rcsb pdb:2WAH|rcsb pdb:3AGV|rcsb pdb:3AVE|rcsb pdb:3AY4|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BDY|rcsb pdb:3BE1|rcsb pdb:3BKY|rcsb pdb:3BN9|rcsb pdb:3BQU|rcsb pdb:3C08|rcsb pdb:3C09|rcsb pdb:3C2S|rcsb pdb:3CFJ|rcsb pdb:3CFK|rcsb pdb:3CSY|rcsb pdb:3D0L|rcsb pdb:3D0V|rcsb pdb:3D6G|rcsb pdb:3D85|rcsb pdb:3DJ9|rcsb pdb:3DNK|rcsb pdb:3DO3|rcsb pdb:3DRO|rcsb pdb:3DRQ|rcsb pdb:3DVG|rcsb pdb:3DVN|rcsb pdb:3EYF|rcsb pdb:3EYO|rcsb pdb:3EYQ|rcsb pdb:3FJT|rcsb pdb:3MCL|rcsb pdb:3O11|rcsb pdb:3RY6|rcsb pdb:3S7G|rcsb pdb:3SGJ|rcsb pdb:3SGK|rcsb pdb:3TV3|rcsb pdb:3TWC|rcsb pdb:3TYG|rcsb pdb:3U0W|rcsb pdb:3U7W|rcsb pdb:3U7Y|rcsb pdb:3V7M|rcsb pdb:3V8C|rcsb pdb:3V95|rcsb pdb:3WJJ|rcsb pdb:1I7Z|rcsb pdb:3WJL|rcsb pdb:3WN5|rcsb pdb:4ACP|rcsb pdb:4B7I|rcsb pdb:4BM7|rcsb pdb:4BSV|rcsb pdb:4BSW|rcsb pdb:4BYH|rcsb pdb:4CDH|rcsb pdb:4D9Q|rcsb pdb:4D9R|rcsb pdb:4DAG|rcsb pdb:4DZ8|rcsb pdb:4EOW|rcsb pdb:4HIX|rcsb pdb:4J12|rcsb pdb:4KU1|rcsb pdb:4LLD|rcsb pdb:4LLM|rcsb pdb:4LLQ|rcsb pdb:4N0U|rcsb pdb:4NQS|rcsb pdb:4NQT|rcsb pdb:4NQU|rcsb pdb:4NWT|rcsb pdb:4NWU|rcsb pdb:4O4Y|rcsb pdb:4O51|rcsb pdb:4Q6Y|rcsb pdb:4Q74|rcsb pdb:4Q7D|rcsb pdb:3WKN|rcsb pdb:4W4N|rcsb pdb:4W4O|rcsb pdb:4WI2|rcsb pdb:4WI3|rcsb pdb:4WI4|rcsb pdb:4WI5|rcsb pdb:4WI6|rcsb pdb:4WI7|rcsb pdb:4WI8|rcsb pdb:4WI9|rcsb pdb:4X4M|rcsb pdb:4X98|rcsb pdb:4X99|rcsb pdb:4XMP|rcsb pdb:4XNY|rcsb pdb:4XXD|rcsb pdb:4ZNE|rcsb pdb:5BW7|rcsb pdb:5D4Q|rcsb pdb:5D6D|rcsb pdb:5DI8|rcsb pdb:5DJ0|rcsb pdb:5DJ2|rcsb pdb:5DJ6|rcsb pdb:5DJ8|rcsb pdb:5DJA|rcsb pdb:5DJC|rcsb pdb:5DJD|rcsb pdb:5DJX|rcsb pdb:5DJY|rcsb pdb:5DJZ|rcsb pdb:5DK0|rcsb pdb:5DK2|rcsb pdb:5DVK|rcsb pdb:5DVL|rcsb pdb:5DVM|rcsb pdb:5DVN|rcsb pdb:5DVO|rcsb pdb:5GSQ|rcsb pdb:5HSF|rcsb pdb:5HY9|rcsb pdb:5HYE|rcsb pdb:5HYF|rcsb pdb:5HYI|rcsb pdb:5IQ7|rcsb pdb:5IQ9|rcsb pdb:5IW3|rcsb pdb:5IW6|rcsb pdb:5JIH|rcsb pdb:5JII|rcsb pdb:5JIK|rcsb pdb:5K33|rcsb pdb:5K64|rcsb pdb:5K65|rcsb pdb:5K8D|rcsb pdb:5KWG|rcsb pdb:5M3V|rcsb pdb:5TPS|rcsb pdb:5U4Y|rcsb pdb:5U52|rcsb pdb:5U66|rcsb pdb:5V43|rcsb pdb:5V4E|rcsb pdb:6DCV|rcsb pdb:6DCW|rcsb pdb:6DE7|rcsb pdb:6F2Z|rcsb pdb:6G1E|rcsb pdb:6N35|rcsb pdb:6YT7|rcsb pdb:7KWO|reactome:R-HSA-166663|rcsb pdb:4XNZ|reactome:R-HSA-173623|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-6785807|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|dip:DIP-29187N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2017/03/30 rogid:OcTJqyse3Mg28AuZJPNbuHXfaWs928303 rogid:1YK8rrTDnOYYKW5wHI48/rYlr5o9606 intact-crc:98D18864225A4A32|rigid:yTSvKEDJ/te2IUGfu1NprahAyQ0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1H1 uniprotkb:P34931 intact:EBI-6151824 intact:EBI-354912|uniprotkb:O75634|uniprotkb:Q2HXR3|uniprotkb:Q8NE72|uniprotkb:A6NNB0|uniprotkb:Q96QC9|uniprotkb:Q9UQM1|uniprotkb:B0UXW8|ensembl:ENSP00000364805|ensembl:ENSP00000372881|ensembl:ENSP00000396486|ensembl:ENSP00000408347 psi-mi:a8e1h1_muhvk(display_long)|uniprotkb:M45(gene name)|psi-mi:M45(display_short)|uniprotkb:RIR1(gene name synonym) psi-mi:hs71l_human(display_long)|uniprotkb:HSPA1L(gene name)|psi-mi:HSPA1L(display_short)|uniprotkb:Heat shock 70 kDa protein 1-Hom(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158634|imex:IM-17331-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:A8E1H1|interpro:IPR034716|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR025735|interpro:IPR039718|go:"GO:0006260"(DNA replication)|go:"GO:0030430"(host cell cytoplasm) refseq:NP_005518.3|ensembl:ENSG00000204390(gene)|ensembl:ENSG00000206383(gene)|ensembl:ENSG00000234258(gene)|ensembl:ENSG00000236251(gene)|ensembl:ENST00000375654(transcript)|ensembl:ENST00000383390(transcript)|ensembl:ENST00000417601(transcript)|ensembl:ENST00000456772(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0072562"(blood microparticle)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P34931|rcsb pdb:3GDQ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2O/mT6rYOIr8HVkTPHmcognnecs69156 rogid:KS02DcMpD2sxSF36hUjKiSdYi4c9606 intact-crc:66D67CF7AF302E6D|rigid:Tzzj2dhucMffrjbBAW0A5sGxrH4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1H1 uniprotkb:Q96QK1 intact:EBI-6151824 intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138 psi-mi:a8e1h1_muhvk(display_long)|uniprotkb:M45(gene name)|psi-mi:M45(display_short)|uniprotkb:RIR1(gene name synonym) psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158634|imex:IM-17331-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:A8E1H1|interpro:IPR034716|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR025735|interpro:IPR039718|go:"GO:0006260"(DNA replication)|go:"GO:0030430"(host cell cytoplasm) refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2O/mT6rYOIr8HVkTPHmcognnecs69156 rogid:EXkMduDQKNCdp876vGF5vna9t389606 intact-crc:66D67CF7AF302E6D|rigid:Tzzj2dhucMffrjbBAW0A5sGxrH4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A8E1H1 uniprotkb:Q4G0F5 intact:EBI-6151824 intact:EBI-6151831|uniprotkb:Q96A55|ensembl:ENSP00000281187|ensembl:ENSP00000434162 psi-mi:a8e1h1_muhvk(display_long)|uniprotkb:M45(gene name)|psi-mi:M45(display_short)|uniprotkb:RIR1(gene name synonym) psi-mi:vp26b_human(display_long)|uniprotkb:Vesicle protein sorting 26B(gene name synonym)|uniprotkb:VPS26B(gene name)|psi-mi:VPS26B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:69156(muhvk)|taxid:69156("Murid herpesvirus 1 (strain K181)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158634|imex:IM-17331-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:A8E1H1|interpro:IPR034716|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR025735|interpro:IPR039718|go:"GO:0006260"(DNA replication)|go:"GO:0030430"(host cell cytoplasm) refseq:NP_443107.1|ensembl:ENSG00000151502(gene)|ensembl:ENST00000281187(transcript)|ensembl:ENST00000525095(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR028934 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:2O/mT6rYOIr8HVkTPHmcognnecs69156 rogid:8NQBMiFKQXjWM4/Vy7swv2pW0V89606 intact-crc:66D67CF7AF302E6D|rigid:Tzzj2dhucMffrjbBAW0A5sGxrH4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q02539 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-932603|uniprotkb:Q3MJ34|ensembl:ENSP00000244573 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h11_human(display_long)|uniprotkb:H1-1(gene name)|psi-mi:H1-1(display_short)|uniprotkb:H1F1(gene name synonym)|uniprotkb:HIST1H1A(gene name synonym)|uniprotkb:Histone H1a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_005316.1|ensembl:ENSG00000124610(gene)|ensembl:ENST00000244573(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q02539|reactome:R-HSA-140342|reactome:R-HSA-2559584 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:4u8P8jFM3onWx43+SxL320urjhk9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P68366 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-351772|uniprotkb:A8MUB1|uniprotkb:P05215|ensembl:ENSP00000248437|uniprotkb:B3KNQ6|intact:EBI-11134566 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:tba4a_human(display_long)|uniprotkb:TUBA4A(gene name)|psi-mi:TUBA4A(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Testis-specific alpha-tubulin(gene name synonym)|uniprotkb:Tubulin H2-alpha(gene name synonym)|uniprotkb:TUBA1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_005991.1|ensembl:ENSG00000127824(gene)|ensembl:ENST00000248437(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68366|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001265481.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P42336 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-2116585|uniprotkb:Q14CW1|uniprotkb:Q99762|ensembl:ENSP00000263967 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pk3ca_human(display_long)|uniprotkb:Phosphoinositide-3-kinase catalytic alpha polypeptide(gene name synonym)|uniprotkb:Serine/threonine protein kinase PIK3CA(gene name synonym)|uniprotkb:PIK3CA(gene name)|psi-mi:PIK3CA(display_short)|uniprotkb:Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha(gene name synonym)|uniprotkb:Phosphoinositide 3-kinase alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:XP_011511196.1|refseq:XP_006713721.1|refseq:NP_006209.2|dip:DIP-42728N|ensembl:ENSG00000121879(gene)|ensembl:ENST00000263967(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001944"(vasculature development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0005943"(phosphatidylinositol 3-kinase complex, class IA)|go:"GO:0005944"(phosphatidylinositol 3-kinase complex, class IB)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006909"(phagocytosis)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030168"(platelet activation)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035004"(phosphatidylinositol 3-kinase activity)|go:"GO:0035005"(1-phosphatidylinositol-4-phosphate 3-kinase activity)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0038028"(insulin receptor signaling pathway via phosphatidylinositol 3-kinase)|go:"GO:0038084"(vascular endothelial growth factor signaling pathway)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0043276"(anoikis)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044029"(hypomethylation of CpG island)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046934"(phosphatidylinositol-4,5-bisphosphate 3-kinase activity)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110053"(regulation of actin filament organization)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR000341(Phosphoinositide 3-kinase, ras-binding)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR003113(Phosphatidylinositol 3-kinase, p85-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR029071|interpro:IPR035892|interpro:IPR036940|interpro:IPR037704|interpro:IPR042236|mint:P42336|rcsb pdb:2ENQ|rcsb pdb:2RD0|rcsb pdb:3HHM|rcsb pdb:3HIZ|rcsb pdb:3ZIM|rcsb pdb:4JPS|rcsb pdb:4L1B|rcsb pdb:4L23|rcsb pdb:4L2Y|rcsb pdb:4OVU|rcsb pdb:4OVV|rcsb pdb:4TUU|rcsb pdb:4TV3|rcsb pdb:4WAF|rcsb pdb:4YKN|rcsb pdb:4ZOP|rcsb pdb:5DXT|rcsb pdb:5FI4|rcsb pdb:5ITD|rcsb pdb:5SW8|rcsb pdb:5SWG|rcsb pdb:5SWO|rcsb pdb:5SWP|rcsb pdb:5SWR|rcsb pdb:5SWT|rcsb pdb:5SX8|rcsb pdb:5SX9|rcsb pdb:5SXA|rcsb pdb:5SXB|rcsb pdb:5SXC|rcsb pdb:5SXD|rcsb pdb:5SXE|rcsb pdb:5SXF|rcsb pdb:5SXI|rcsb pdb:5SXJ|rcsb pdb:5SXK|rcsb pdb:5UBR|rcsb pdb:5UK8|rcsb pdb:5UKJ|rcsb pdb:5UL1|rcsb pdb:5XGH|rcsb pdb:5XGI|rcsb pdb:5XGJ|rcsb pdb:6GVF|rcsb pdb:6GVG|rcsb pdb:6GVH|rcsb pdb:6GVI|rcsb pdb:6NCT|rcsb pdb:6OAC|rcsb pdb:6PYS|rcsb pdb:6VO7|rcsb pdb:7JIU|rcsb pdb:7K6M|rcsb pdb:7K6N|rcsb pdb:7K6O|rcsb pdb:7K71|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1236382|reactome:R-HSA-1250342|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-180292|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-1963642|reactome:R-HSA-198203|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-210993|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5637810|reactome:R-HSA-5654689|reactome:R-HSA-5654695|reactome:R-HSA-5654710|reactome:R-HSA-5654720|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-9009391|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9027276|reactome:R-HSA-9028335|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9603381|reactome:R-HSA-9607240|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|rcsb pdb:5DXH|reactome:R-HSA-9703465|reactome:R-HSA-9703648 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:YIZWt9VfCmyBCWYkqAEaMAEsl3w9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P04075 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-709613|uniprotkb:Q6FH76|uniprotkb:Q96B15|uniprotkb:Q9BWD9|uniprotkb:B4DXI7|uniprotkb:Q6FI10|uniprotkb:Q9UCN2|ensembl:ENSP00000400452|ensembl:ENSP00000455700|ensembl:ENSP00000455800|ensembl:ENSP00000494188 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:aldoa_human(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Lung cancer antigen NY-LU-1(gene name synonym)|uniprotkb:ALDOA(gene name)|psi-mi:ALDOA(display_short)|uniprotkb:ALDA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_000025.1|refseq:NP_001121089.1|refseq:NP_001230106.1|refseq:NP_908930.1|refseq:NP_908932.1|refseq:XP_011544070.1|ensembl:ENSG00000149925(gene)|ensembl:ENST00000412304(transcript)|ensembl:ENST00000563060(transcript)|ensembl:ENST00000569545(transcript)|ensembl:ENST00000643777(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0061827"(sperm head)|go:"GO:0070061"(fructose binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P04075|rcsb pdb:1ALD|rcsb pdb:2ALD|rcsb pdb:4ALD|rcsb pdb:5KY6|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:/UgTtKPQj2ZyKznKIfE9OVUcDFI9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P35579 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-350338|uniprotkb:O60805|ensembl:ENSP00000216181|uniprotkb:Q86T83|intact:EBI-1054343|uniprotkb:A8K6E4|uniprotkb:Q60FE2 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_002464.1|ensembl:ENSG00000100345(gene)|ensembl:ENST00000216181(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|refseq:XP_011528499.1|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0097513"(myosin II filament)|go:"GO:1903919"(negative regulation of actin filament severing)|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q99729 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P07910 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-357966|uniprotkb:P22628|uniprotkb:Q53EX2|uniprotkb:Q59FD3|uniprotkb:Q5FWE8|uniprotkb:Q86SF8|uniprotkb:Q86U45|uniprotkb:Q96HK7|uniprotkb:Q96HM4|uniprotkb:Q96IY5|uniprotkb:Q9BTS3|uniprotkb:D3DS19|uniprotkb:D3DS22|intact:EBI-28976506|ensembl:ENSP00000404848|ensembl:ENSP00000451291|ensembl:ENSP00000452276 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpc_human(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001070910.1|refseq:NP_001070911.1|refseq:NP_004491.2|refseq:NP_112604.2|ensembl:ENSP00000404848|ensembl:ENST00000430246|ensembl:ENSP00000442816|ensembl:ENST00000553300|ensembl:ENSP00000450544|ensembl:ENSP00000451291|ensembl:ENST00000554969|ensembl:ENSP00000452276|ensembl:ENSP00000450725|ensembl:ENST00000555883|ensembl:ENSP00000450629|ensembl:ENST00000556628|ensembl:ENSP00000451652|ensembl:ENST00000556897|ensembl:ENSP00000451176|refseq:XP_011535010.1|refseq:XP_011535011.1|refseq:XP_011535012.1|refseq:XP_011535013.1|refseq:XP_011535014.1|refseq:XP_016876741.1|refseq:XP_016876742.1|dip:DIP-29854N|refseq:XP_006720188.1|ensembl:ENSG00000092199(gene)|ensembl:ENST00000420743(transcript)|ensembl:ENST00000554455(transcript)|ensembl:ENST00000557201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979|mint:P07910|rcsb pdb:1TXP|rcsb pdb:1WF2|rcsb pdb:2MXY|rcsb pdb:2MZ1|rcsb pdb:3LN4|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:Fj5tiH0wrNUjTnsURIg8dB8laMg9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P11940 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q15365 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-946095|uniprotkb:Q13157|uniprotkb:Q14975|ensembl:ENSP00000305556 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pcbp1_human(display_long)|uniprotkb:PCBP1(gene name)|psi-mi:PCBP1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Nucleic acid-binding protein SUB2.3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_006187.2|dip:DIP-38136N|ensembl:ENSG00000169564(gene)|ensembl:ENST00000303577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15365|rcsb pdb:1WVN|rcsb pdb:1ZTG|rcsb pdb:3VKE|reactome:R-HSA-72163|reactome:R-HSA-72203 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:x72fawo4plQ+ipfqIoREIDHc2bA9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q9GZV4 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-748028|ensembl:ENSP00000295822|uniprotkb:B2R4V5 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:if5a2_human(display_long)|uniprotkb:Eukaryotic initiation factor 5A isoform 2(gene name synonym)|uniprotkb:EIF5A2(gene name)|psi-mi:EIF5A2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 go:"GO:0010509"(polyamine homeostasis)|ensembl:ENSG00000163577(gene)|go:"GO:0015031"(protein transport)|go:"GO:0043022"(ribosome binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensembl:ENST00000295822(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0051028"(mRNA transport)|refseq:NP_065123.1|interpro:IPR001884("Eukaryotic initiation factor 5A hypusine (eIF-5A)")|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR019769|interpro:IPR020189|reactome:R-HSA-204626 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:cm95o/2pG+p6gBFemWzLNcMWgt89606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P62136 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-357253|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802|uniprotkb:B2R908|intact:EBI-2623163|uniprotkb:Q07161|intact:EBI-2556927|uniprotkb:A6NNR3|ensembl:ENSP00000365936 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pp1a_human(display_long)|uniprotkb:PPP1CA(gene name)|psi-mi:PPP1CA(display_short)|uniprotkb:PPP1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001008709.1|refseq:NP_002699.1|refseq:NP_996756.1|dip:DIP-221N|dip:DIP-38195N|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051301"(cell division)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|mint:P62136|rcsb pdb:3E7A|rcsb pdb:3E7B|rcsb pdb:3EGG|rcsb pdb:3EGH|rcsb pdb:3HVQ|rcsb pdb:3N5U|rcsb pdb:3V4Y|rcsb pdb:4G9J|rcsb pdb:4MOV|rcsb pdb:4MOY|rcsb pdb:4MP0|rcsb pdb:4XPN|rcsb pdb:5IOH|rcsb pdb:6ALZ|rcsb pdb:6CZO|rcsb pdb:6DCX|rcsb pdb:6DNO|rcsb pdb:6G0I|rcsb pdb:6G0J|rcsb pdb:6GHM|rcsb pdb:6OBN|rcsb pdb:6OBP|rcsb pdb:6OBQ|rcsb pdb:6OBR|rcsb pdb:6OBS|rcsb pdb:6OBU|rcsb pdb:6ZEE|rcsb pdb:6ZEF|rcsb pdb:6ZEG|rcsb pdb:6ZEH|rcsb pdb:6ZEI|rcsb pdb:6ZEJ|rcsb pdb:6ZK6|reactome:R-HSA-163560|reactome:R-HSA-180024|reactome:R-HSA-2173788|reactome:R-HSA-400253|go:"GO:0098793"(presynapse)|ensembl:ENSG00000172531(gene)|ensembl:ENST00000376745(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030324"(lung development) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:IMypaKng+5AECbCd3N72pgzUlxQ9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P08865 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-354112|uniprotkb:Q6NSD1|uniprotkb:Q6NXQ8|uniprotkb:Q86VC0|uniprotkb:P11085|uniprotkb:P12030|uniprotkb:Q16471|uniprotkb:Q6IPD1|uniprotkb:Q6IPD2|ensembl:ENSP00000346067 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rssa_human(display_long)|uniprotkb:RPSA(gene name)|psi-mi:RPSA(display_short)|uniprotkb:LAMBR(gene name synonym)|uniprotkb:LAMR1(gene name synonym)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:Colon carcinoma laminin-binding protein(gene name synonym)|uniprotkb:NEM/1CHD4(gene name synonym)|uniprotkb:Multidrug resistance-associated protein MGr1-Ag(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_002286.2|refseq:NP_001291217.1|dip:DIP-32878N|ensembl:ENSG00000168028(gene)|ensembl:ENST00000301821(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0007155"(cell adhesion)|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZOJ|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|go:"GO:0043236"(laminin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P08865|rcsb pdb:3BCH|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:Jpv3I3G5C297fHfNwIqyB9Pf8/A9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P46779 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-366357|uniprotkb:Q6IAY0|uniprotkb:Q96FX1|uniprotkb:Q9BWQ0|uniprotkb:B2R4A6|uniprotkb:B4DEP9|uniprotkb:E9PB24|uniprotkb:C9JB50|uniprotkb:G5E9L2|ensembl:ENSP00000342787|ensembl:ENSP00000453319 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rl28_human(display_long)|uniprotkb:RPL28(gene name)|psi-mi:RPL28(display_short)|uniprotkb:Large ribosomal subunit protein eL28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001129608.1|refseq:NP_001129609.1|refseq:NP_000982.2|refseq:NP_001129606.1|refseq:NP_001129607.1|ensembl:ENSG00000108107(gene)|ensembl:ENST00000344063(transcript)|ensembl:ENST00000559463(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002672(Ribosomal protein L28e)|interpro:IPR029004|mint:P46779|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:I7Me1zjfxk98g6C2NoYOWlmrYVc9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q8N0Y7 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-6151851|uniprotkb:Q8NI24|uniprotkb:Q5JPN2|uniprotkb:Q8NI26|uniprotkb:Q8NI25|ensembl:ENSP00000412189 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pgam4_human(display_long)|uniprotkb:PGAM3(gene name synonym)|uniprotkb:PGAM4(gene name)|psi-mi:PGAM4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001025062.1|ensembl:ENSG00000226784(gene)|ensembl:ENST00000458128(transcript)|go:"GO:0004082"(bisphosphoglycerate mutase activity)|go:"GO:0004619"(phosphoglycerate mutase activity)|go:"GO:0006096"(glycolytic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097228"(sperm principal piece)|go:"GO:1902093"(positive regulation of flagellated sperm motility)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR005952(Phosphoglycerate mutase 1)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:i+aWW0w/1hTXQIqezMj/04KaYfI9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P22492 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q8N163 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|ensembl:ENSP00000310670|ensembl:ENSP00000373930|uniprotkb:B2RB79|uniprotkb:D3DSR6 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_066997.3|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|interpro:IPR028811|mint:Q8N163|reactome:R-HSA-3371453|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|dip:DIP-38122N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P55795 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352823|ensembl:ENSP00000361927|uniprotkb:Q9HHA7|uniprotkb:A1L400 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrh2_human(display_long)|uniprotkb:HNRNPH2(gene name)|psi-mi:HNRNPH2(display_short)|uniprotkb:FTP3(gene name synonym)|uniprotkb:HNRPH2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein H'(gene name synonym)|uniprotkb:FTP-3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000126945(gene)|ensembl:ENST00000316594(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P55795|rcsb pdb:1WEZ|rcsb pdb:1WG5|rcsb pdb:6DG1|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001027565.1|refseq:NP_062543.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:811j5syFsbk/QSaZv/ag9QsFUEQ9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P22626 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P06748 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930|ensembl:ENSP00000428755 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_002511.1|refseq:NP_954654.1|refseq:NP_001032827.1|dip:DIP-30932N|ensembl:ENSG00000181163(gene)|ensembl:ENST00000296930(transcript)|ensembl:ENST00000517671(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001652"(granular component)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006407"(rRNA export from nucleus)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019843"(rRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042255"(ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060699"(regulation of endoribonuclease activity)|go:"GO:0060735"(regulation of eIF2 alpha phosphorylation by dsRNA)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902629"(regulation of mRNA stability involved in cellular response to UV)|go:"GO:1902751"(positive regulation of cell cycle G2/M phase transition)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P26599 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-350540|ensembl:ENSP00000014112|intact:EBI-744534|uniprotkb:Q9BUQ0 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ptbp1_human(display_long)|uniprotkb:PTBP1(gene name)|psi-mi:PTBP1(display_short)|uniprotkb:PTB(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein I(gene name synonym)|uniprotkb:57 kDa RNA-binding protein PPTB-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_002810.1|refseq:NP_114367.1|refseq:NP_114368.1|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0016020"(membrane)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0051148"(negative regulation of muscle cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034798|interpro:IPR035000|interpro:IPR035001|interpro:IPR035979|mint:P26599|rcsb pdb:1QM9|rcsb pdb:1SJQ|ensembl:ENSG00000011304(gene)|ensembl:ENST00000349038(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0008380"(RNA splicing)|rcsb pdb:2AD9|rcsb pdb:2ADB|rcsb pdb:2ADC|rcsb pdb:2EVZ|rcsb pdb:2N3O|rcsb pdb:3ZZY|rcsb pdb:3ZZZ|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|rcsb pdb:1SJR - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:fkSnYJELgHxDP0oAQEjBmSX0HIs9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P57721 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-954627|uniprotkb:Q8N9K6|uniprotkb:Q96EP6|uniprotkb:A8MPS2|uniprotkb:A8MQ26|uniprotkb:B7WNN9|uniprotkb:B7WPC1|ensembl:ENSP00000383168|ensembl:ENSP00000505796|intact:EBI-2555264 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pcbp3_human(display_long)|uniprotkb:PCBP3-overlapping transcript(gene name synonym)|uniprotkb:PCBP3-overlapping transcript 1(gene name synonym)|uniprotkb:PCBP3OT(gene name synonym)|uniprotkb:PCBP3(gene name)|psi-mi:PCBP3(display_short)|uniprotkb:Alpha-CP3(gene name synonym)|uniprotkb:PCBP3-OT1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000183570(gene)|ensembl:ENST00000400314(transcript)|ensembl:ENST00000681687(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:P57721|refseq:NP_001123613.1|refseq:NP_065389.2|refseq:NP_001335167.1|refseq:NP_001335171.1|refseq:NP_001335173.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:FM/z2+gksm+t2UY+BhMIl/myjqk9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P07900 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|ensembl:ENSP00000216281|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 go:"GO:0009409"(response to cold)|go:"GO:0016020"(membrane)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|ensembl:ENST00000216281(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000080824(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043335"(protein unfolding)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1UY8|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2BYH|rcsb pdb:2VCJ|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3B24|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5LO1|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6CYH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7LSZ|rcsb pdb:7LT0|reactome:R-HSA-1227986|reactome:R-HSA-1236382|rcsb pdb:6TN4|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9665233|reactome:R-HSA-9664565|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3K99|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:3T0H|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:4YKZ|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|refseq:NP_001017963.2|refseq:NP_005339.3|dip:DIP-27595N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P60174 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-717475|uniprotkb:D3DUS9|uniprotkb:P00938|uniprotkb:Q6IS07|uniprotkb:Q8WWD0|uniprotkb:Q96AG5|uniprotkb:Q6FHP9|uniprotkb:B7Z5D8|ensembl:ENSP00000379933 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:tpis_human(display_long)|uniprotkb:Triose-phosphate isomerase(gene name synonym)|uniprotkb:TPI1(gene name)|psi-mi:TPI1(display_short)|uniprotkb:TPI(gene name synonym)|uniprotkb:Methylglyoxal synthase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_000356.1|refseq:NP_001152759.1|refseq:NP_001244955.1|ensembl:ENSG00000111669(gene)|ensembl:ENST00000396705(transcript)|go:"GO:0004807"(triose-phosphate isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0008929"(methylglyoxal synthase activity)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000652(Triosephosphate isomerase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR020861|interpro:IPR022896|interpro:IPR035990|mint:P60174|rcsb pdb:1HTI|rcsb pdb:1KLG|rcsb pdb:1KLU|rcsb pdb:1WYI|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2JK2|rcsb pdb:2VOM|rcsb pdb:4BR1|rcsb pdb:4E41|rcsb pdb:4POC|rcsb pdb:4POD|rcsb pdb:4UNK|rcsb pdb:4UNL|rcsb pdb:4ZVJ|rcsb pdb:6C2G|rcsb pdb:6D43|rcsb pdb:6NLH|rcsb pdb:6UP1|rcsb pdb:6UP5|rcsb pdb:6UP8|rcsb pdb:6UPF|reactome:R-HSA-70171|reactome:R-HSA-70263 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:FaLt6wGI1Bz2Z81gX35p7sOiMbE9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P31943 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168|ensembl:ENSP00000377082|ensembl:ENSP00000397797|ensembl:ENSP00000492076|ensembl:ENSP00000495786 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_005511.1|refseq:NP_001244222.1|ensembl:ENSG00000169045(gene)|ensembl:ENSG00000284254(gene)|ensembl:ENST00000356731(transcript)|ensembl:ENST00000393432(transcript)|ensembl:ENST00000442819(transcript)|ensembl:ENST00000638505(transcript)|ensembl:ENST00000643310(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P18669 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-717905|uniprotkb:Q9BWC0|ensembl:ENSP00000359991 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pgam1_human(display_long)|uniprotkb:Phosphoglycerate mutase isozyme B(gene name synonym)|uniprotkb:BPG-dependent PGAM 1(gene name synonym)|uniprotkb:PGAM1(gene name)|psi-mi:PGAM1(display_short)|uniprotkb:CDABP0006(orf name)|uniprotkb:PGAMA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_002620.1|ensembl:ENSG00000171314(gene)|ensembl:ENST00000334828(transcript)|go:"GO:0004082"(bisphosphoglycerate mutase activity)|go:"GO:0004619"(phosphoglycerate mutase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006096"(glycolytic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043456"(regulation of pentose-phosphate shunt)|go:"GO:0045730"(respiratory burst)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR005952(Phosphoglycerate mutase 1)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|mint:P18669|rcsb pdb:1LJD|rcsb pdb:1YFK|rcsb pdb:1YJX|rcsb pdb:4GPI|rcsb pdb:4GPZ|rcsb pdb:5Y2I|rcsb pdb:5Y2U|rcsb pdb:5Y35|rcsb pdb:5Y64|rcsb pdb:5Y65|rcsb pdb:5ZRM|rcsb pdb:5ZS8|rcsb pdb:6ISN|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:GI6jwRrX08owCyzx8KnRU8QP2rg9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P06454 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-2682091|uniprotkb:Q15249|uniprotkb:Q15592|ensembl:ENSP00000344547 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ptma_human(display_long)|uniprotkb:TMSA(gene name synonym)|uniprotkb:PTMA(gene name)|psi-mi:PTMA(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001092755.1|refseq:NP_002814.3|ensembl:ENSG00000187514(gene)|ensembl:ENST00000341369(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR004931(Prothymosin/parathymosin)|mint:P06454|rcsb pdb:2L9I|rcsb pdb:2MNQ|dip:DIP-40743N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:scRCSTJyl5e12uNhBR+L4CKQ6Ac9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q13310 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-372844|uniprotkb:Q6P0N3|uniprotkb:B1ANQ8|ensembl:ENSP00000361948|intact:EBI-877641|uniprotkb:Q4VC03 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pabp4_human(display_long)|uniprotkb:PABPC4(gene name)|psi-mi:PABPC4(display_short)|uniprotkb:APP1(gene name synonym)|uniprotkb:PABP4(gene name synonym)|uniprotkb:"Inducible poly(A)-binding protein"(gene name synonym)|uniprotkb:Activated-platelet protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001129126.1|refseq:NP_003810.1|ensembl:ENSG00000090621(gene)|ensembl:ENST00000372857(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006412"(translation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0061515"(myeloid cell development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:Q13310|refseq:NP_001129125.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:u1qCM3o5X7jLIa1vyqFCIH7v01w9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q00839 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-351126|uniprotkb:O75507|uniprotkb:Q8N174|uniprotkb:Q96HY9|uniprotkb:Q9BQ09|ensembl:ENSP00000491215 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpu_human(display_long)|uniprotkb:HNRNPU(gene name)|psi-mi:HNRNPU(display_short)|uniprotkb:SAFA(gene name synonym)|uniprotkb:U21.1(gene name synonym)|uniprotkb:HNRPU(gene name synonym)|uniprotkb:p120(gene name synonym)|uniprotkb:pp120(gene name synonym)|uniprotkb:C1orf199(gene name synonym)|uniprotkb:GRIP120(gene name synonym)|uniprotkb:Nuclear p120 ribonucleoprotein(gene name synonym)|uniprotkb:Scaffold-attachment factor A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_004492.2|refseq:NP_114032.2|ensembl:ENSG00000153187(gene)|ensembl:ENST00000640218(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:1990498"(mitotic spindle microtubule)|go:"GO:0098577"(inactive sex chromosome)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR026745|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q00839|rcsb pdb:1ZRJ|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990280"(RNA localization to chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006396"(RNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008143"("poly(A) binding")|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0017130"("poly(C) RNA binding")|go:"GO:0030496"(midbody)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|refseq:XP_016856604.1|refseq:XP_016856605.1|refseq:XP_016856606.1|dip:DIP-684N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:n73PY0Vis+D5Iq0q77h5Ck2V4789606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P62269 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352451|ensembl:ENSP00000211372|ensembl:ENSP00000393241|ensembl:ENSP00000403175|ensembl:ENSP00000412583|ensembl:ENSP00000416110|uniprotkb:P25232|uniprotkb:Q6IPF8|uniprotkb:Q5SUJ3 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rs18_human(display_long)|uniprotkb:RPS18(gene name)|psi-mi:RPS18(display_short)|uniprotkb:D6S218E(gene name synonym)|uniprotkb:Ke-3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS13(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_072045.1|ensembl:ENSG00000096150(gene)|ensembl:ENSG00000223367(gene)|ensembl:ENSG00000226225(gene)|ensembl:ENSG00000231500(gene)|ensembl:ENSG00000235650(gene)|ensembl:ENST00000211372(transcript)|ensembl:ENST00000434122(transcript)|ensembl:ENST00000439602(transcript)|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENST00000454021(transcript)|ensembl:ENST00000457341(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001892(Ribosomal protein S13)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR018269|interpro:IPR027437|mint:P62269|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|dip:DIP-32892N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:yOHgKM/BuvgGdqp1OEVPeuiABg89606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P12277 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-357706|uniprotkb:Q2LE07|uniprotkb:A8K236|uniprotkb:B2R5R4|uniprotkb:Q6FG40|uniprotkb:Q9UC66|ensembl:ENSP00000299198 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:kcrb_human(display_long)|uniprotkb:CKB(gene name)|psi-mi:CKB(display_short)|uniprotkb:CKBB(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:Brain creatine kinase(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001814.2|go:"GO:0005829"(cytosol)|ensembl:ENSG00000166165(gene)|ensembl:ENST00000348956(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12277|rcsb pdb:3B6R|rcsb pdb:3DRB|rcsb pdb:3DRE|rcsb pdb:6V9H|go:"GO:0021762"(substantia nigra development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|reactome:R-HSA-71288|reactome:R-HSA-9696264|dip:DIP-52968N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:WLRnU8sRUfJQoaPY0edGi9xiR+g9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P23528 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352733|uniprotkb:Q53Y87|uniprotkb:Q9UCA2|uniprotkb:B3KUQ1|ensembl:ENSP00000309629|ensembl:ENSP00000432660 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:cof1_human(display_long)|uniprotkb:CFL1(gene name)|psi-mi:CFL1(display_short)|uniprotkb:CFL(gene name synonym)|uniprotkb:Cofilin, non-muscle isoform(gene name synonym)|uniprotkb:18 kDa phosphoprotein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_005498.1|ensembl:ENSG00000172757(gene)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR027234|interpro:IPR029006|mint:P23528|rcsb pdb:1Q8G|rcsb pdb:1Q8X|rcsb pdb:3J0S|rcsb pdb:4BEX|rcsb pdb:5HVK|rcsb pdb:5L6W|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|reactome:R-HSA-114608|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-399954|reactome:R-HSA-5627117|reactome:R-HSA-8950505|ensembl:ENST00000308162(transcript)|ensembl:ENST00000525451(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0009615"(response to virus)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0031258"(lamellipodium membrane)|dip:DIP-33000N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:wgBEUL55sE9G9Be1f/A1OA6KRb49606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:O14654 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-356594|ensembl:ENSP00000505547 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q08211 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352022|intact:EBI-1058470|uniprotkb:Q5VY62|uniprotkb:Q6PD69|uniprotkb:Q99556|uniprotkb:B2RNV4|uniprotkb:Q05CI5|uniprotkb:Q12803|uniprotkb:Q32Q22|ensembl:ENSP00000356520 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:dhx9_human(display_long)|uniprotkb:DHX9(gene name)|psi-mi:DHX9(display_short)|uniprotkb:DDX9(gene name synonym)|uniprotkb:NDH2(gene name synonym)|uniprotkb:DExH-box helicase 9(gene name synonym)|uniprotkb:RNA helicase A(gene name synonym)|uniprotkb:LKP(gene name synonym)|uniprotkb:Nuclear DNA helicase II(gene name synonym)|uniprotkb:DEAH box protein 9(gene name synonym)|uniprotkb:Leukophysin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001348.2|dip:DIP-31504N|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033679"(3'-5' DNA/RNA helicase activity)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045142"(triplex DNA binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0097165"(nuclear stress granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1905172"(RISC complex binding)|go:"GO:1905538"(polysome binding)|go:"GO:1905698"(positive regulation of polysome binding)|go:"GO:1990518"(single-stranded 3'-5' DNA helicase activity)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000765"(regulation of cytoplasmic translation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR044445|interpro:IPR044446|interpro:IPR044447|mint:Q08211|rcsb pdb:3LLM|rcsb pdb:3VYX|rcsb pdb:3VYY|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-72163|go:"GO:1904973"(positive regulation of viral translation)|ensembl:ENSG00000135829(gene)|ensembl:ENST00000367549(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006260"(DNA replication)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0016604"(nuclear body) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:b0VP2Frtvwa9WbYVMwB6TbV2uGU9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P07737 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-713780|ensembl:ENSP00000225655|uniprotkb:Q53Y44 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:prof1_human(display_long)|uniprotkb:Profilin I(gene name synonym)|uniprotkb:PFN1(gene name)|psi-mi:PFN1(display_short)|uniprotkb:Epididymis tissue protein Li 184a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000108518(gene)|ensembl:ENST00000225655(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060074"(synapse maturation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0072562"(blood microparticle)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900029"(positive regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR029892|interpro:IPR036140|mint:P07737|rcsb pdb:1AWI|rcsb pdb:1CF0|rcsb pdb:1CJF|rcsb pdb:1FIK|rcsb pdb:1FIL|rcsb pdb:1PFL|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|rcsb pdb:4X1L|rcsb pdb:4X1M|rcsb pdb:4X25|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6NBW|reactome:R-HSA-114608|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|reactome:R-HSA-4086400|reactome:R-HSA-5663220|reactome:R-HSA-376176|refseq:NP_005013.1|dip:DIP-30N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:CncaC5RMylvzFLhqzpS+VbhQn6I9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P07195 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-358748|ensembl:ENSP00000229319|ensembl:ENSP00000379386 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ldhb_human(display_long)|uniprotkb:LDHB(gene name)|psi-mi:LDHB(display_short)|uniprotkb:LDH heart subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001167568.1|refseq:NP_002291.1|refseq:NP_001302466.1|ensembl:ENSG00000111716(gene)|ensembl:ENST00000350669(transcript)|ensembl:ENST00000396076(transcript)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|mint:P07195|rcsb pdb:1I0Z|rcsb pdb:1T2F|reactome:R-HSA-70268 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:umdj6fjSO7+4SM9Hrl1/K2EiKls9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P13639 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352560|uniprotkb:Q58J86|uniprotkb:B2RMP5|uniprotkb:D6W618|ensembl:ENSP00000307940 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ef2_human(display_long)|uniprotkb:EEF2(gene name)|psi-mi:EEF2(display_short)|uniprotkb:EF2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001952.1|ensembl:ENSG00000167658(gene)|ensembl:ENST00000309311(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0007568"(aging)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051593"(response to folic acid)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P13639|rcsb pdb:4V6X|rcsb pdb:6D9J|rcsb pdb:6Z6M|rcsb pdb:6Z6N|reactome:R-HSA-156902|reactome:R-HSA-5336415|reactome:R-HSA-5358493|reactome:R-HSA-6798695|reactome:R-HSA-8876725 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:US1dzGQ5V1oBXVtYeGt5H3HCIr09606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P48643 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P40926 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-721232|uniprotkb:O43682|uniprotkb:B4DE44|uniprotkb:E9PDB2|uniprotkb:A8K414|uniprotkb:B2RE78|ensembl:ENSP00000327070 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:mdhm_human(display_long)|uniprotkb:MDH2(gene name)|psi-mi:MDH2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_005909.2|refseq:NP_001269332.1|refseq:NP_001269333.1|ensembl:ENSG00000146701(gene)|ensembl:ENST00000315758(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006108"(malate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016020"(membrane)|go:"GO:0030060"(L-malate dehydrogenase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0046554"("malate dehydrogenase (NADP+) activity")|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001252(Malate dehydrogenase, active site)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR010097(Malate dehydrogenase, NAD-dependent, eukaryotes and gamma proteobacteria)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR022383|interpro:IPR036291|mint:P40926|rcsb pdb:2DFD|rcsb pdb:4WLE|rcsb pdb:4WLF|rcsb pdb:4WLN|rcsb pdb:4WLO|rcsb pdb:4WLU|rcsb pdb:4WLV|reactome:R-HSA-70263|reactome:R-HSA-71403 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:Ur2aO+2M7e/ftD8RlhPMHBc8/JU9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q12906 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-78756|uniprotkb:A8K6F2|uniprotkb:O43409|uniprotkb:Q6P1X1|uniprotkb:Q86XY7|uniprotkb:Q99544|uniprotkb:Q99545|uniprotkb:Q9BZH4|uniprotkb:Q9BZH5|uniprotkb:Q9NQ95|uniprotkb:Q9NQ96|uniprotkb:Q9NQ97|uniprotkb:Q9NQ98|uniprotkb:Q9NQ99|uniprotkb:Q9NQA0|uniprotkb:Q9NQA1|uniprotkb:Q9NQA2|uniprotkb:Q9NRN2|uniprotkb:Q9NRN3|uniprotkb:Q9NRN4|uniprotkb:Q9UMZ9|uniprotkb:Q9UN00|uniprotkb:Q9UN84|uniprotkb:Q9UNA2|ensembl:ENSP00000468156|intact:EBI-10970055|uniprotkb:G5E9M5 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ilf3_human(display_long)|uniprotkb:ILF3(gene name)|psi-mi:ILF3(display_short)|uniprotkb:MPHOSPH4(gene name synonym)|uniprotkb:NF90(gene name synonym)|uniprotkb:Nuclear factor of activated T-cells 90 kDa(gene name synonym)|uniprotkb:Double-stranded RNA-binding protein 76(gene name synonym)|uniprotkb:Translational control protein 80(gene name synonym)|uniprotkb:Nuclear factor associated with dsRNA(gene name synonym)|uniprotkb:M-phase phosphoprotein 4(gene name synonym)|uniprotkb:DRBF(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000129351(gene)|ensembl:ENST00000590261(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051607"(defense response to virus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR033099|interpro:IPR043519|mint:Q12906|rcsb pdb:2L33|rcsb pdb:3P1X|refseq:NP_001131145.1|refseq:NP_004507.2|refseq:NP_036350.2|refseq:NP_060090.2|refseq:NP_703194.1|refseq:XP_016882252.1|refseq:XP_011526286.2|dip:DIP-29853N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:iri+WBUtektANRSCpBO1XBCd9Wk9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q12905 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-357925|uniprotkb:A6NDB0|uniprotkb:Q5SR10|uniprotkb:Q5SR11|uniprotkb:Q7L7R3|uniprotkb:Q9BWD4|uniprotkb:Q9P1N0|uniprotkb:B2R8G7|ensembl:ENSP00000355011 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ilf2_human(display_long)|uniprotkb:PRO3063(orf name)|uniprotkb:NF45(gene name synonym)|uniprotkb:ILF2(gene name)|psi-mi:ILF2(display_short)|uniprotkb:Nuclear factor of activated T-cells 45 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_004506.2|refseq:NP_001254738.1|ensembl:ENSG00000143621(gene)|ensembl:ENST00000361891(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR043519|mint:Q12905|reactome:R-HSA-6798695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:HwUDuY6Ev7csoTThxZCW8nJT88o9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P55265 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-2462104|uniprotkb:B1AQR0|uniprotkb:O15223|uniprotkb:O43859|uniprotkb:O43860|uniprotkb:Q9BYM3|uniprotkb:Q9BYM4|uniprotkb:B1AQQ9|uniprotkb:D3DV76|ensembl:ENSP00000357459 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:dsrad_human(display_long)|uniprotkb:ADAR(gene name)|psi-mi:ADAR(display_short)|uniprotkb:ADAR1(gene name synonym)|uniprotkb:DSRAD(gene name synonym)|uniprotkb:G1P1(gene name synonym)|uniprotkb:IFI4(gene name synonym)|uniprotkb:136 kDa double-stranded RNA-binding protein(gene name synonym)|uniprotkb:K88DSRBP(gene name synonym)|uniprotkb:Interferon-inducible protein 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001020278.1|refseq:NP_001102.2|refseq:NP_001180424.1|refseq:NP_056655.2|refseq:NP_056656.2|refseq:XP_006711174.1|refseq:XP_006711175.1|refseq:XP_006711176.1|dip:DIP-29310N|ensembl:ENSG00000160710(gene)|ensembl:ENST00000368474(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002566"(somatic diversification of immune receptors via somatic mutation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003726"(double-stranded RNA adenosine deaminase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006382"(adenosine to inosine editing)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0008251"(tRNA-specific adenosine deaminase activity)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0016553"(base conversion or substitution editing)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0060216"(definitive hemopoiesis)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900369"(negative regulation of RNA interference)|interpro:IPR002466(Adenosine deaminase/editase)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036388|interpro:IPR036390|interpro:IPR042371|interpro:IPR044456|interpro:IPR044457|mint:P55265|rcsb pdb:1QBJ|rcsb pdb:1QGP|rcsb pdb:1XMK|rcsb pdb:2ACJ|rcsb pdb:2GXB|rcsb pdb:2L54|rcsb pdb:2MDR|rcsb pdb:3F21|rcsb pdb:3F22|rcsb pdb:3F23|rcsb pdb:3IRQ|rcsb pdb:3IRR|rcsb pdb:5ZU1|rcsb pdb:5ZUO|rcsb pdb:5ZUP|rcsb pdb:7C0I|reactome:R-HSA-75102|reactome:R-HSA-77042|reactome:R-HSA-909733|go:"GO:0051607"(defense response to virus) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:rP/Yr/h8WLSFNdIuqWnYtZjZ9qI9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P14866 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-719024|uniprotkb:Q9H3P3|uniprotkb:A6ND69|uniprotkb:A6NIT8|ensembl:ENSP00000221419|ensembl:ENSP00000489021 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpl_human(display_long)|uniprotkb:HNRPL(gene name synonym)|uniprotkb:HNRNPL(gene name)|psi-mi:HNRNPL(display_short)|uniprotkb:P/OKcl.14(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001005335.1|refseq:NP_001524.2|refseq:XP_011525191.1|ensembl:ENSG00000282947(gene)|ensembl:ENST00000221419(transcript)|ensembl:ENST00000634753(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097157"(pre-mRNA intronic binding)|ensembl:ENSG00000104824(gene)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034816|interpro:IPR034817|interpro:IPR035005|interpro:IPR035008|interpro:IPR035979|mint:P14866|rcsb pdb:3R27|rcsb pdb:3TO8|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:1990904"(ribonucleoprotein complex)|dip:DIP-36355N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:vOfznm03e6Ottg6BptYHmR9qJEc9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P30041 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-2255129|uniprotkb:A8JZY7|uniprotkb:P32077|uniprotkb:Q5TAH4|uniprotkb:Q5ZEZ8|ensembl:ENSP00000342026 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:prdx6_human(display_long)|uniprotkb:PRDX6(gene name)|psi-mi:PRDX6(display_short)|uniprotkb:AOP2(gene name synonym)|uniprotkb:KIAA0106(gene name synonym)|uniprotkb:Antioxidant protein 2(gene name synonym)|uniprotkb:1-Cys peroxiredoxin(gene name synonym)|uniprotkb:Acidic calcium-independent phospholipase A2(gene name synonym)|uniprotkb:Non-selenium glutathione peroxidase(gene name synonym)|uniprotkb:24 kDa protein(gene name synonym)|uniprotkb:Liver 2D page spot 40(gene name synonym)|uniprotkb:Red blood cells page spot 12(gene name synonym)|uniprotkb:Glutathione-dependent peroxiredoxin(gene name synonym)|uniprotkb:Lysophosphatidylcholine acyltransferase 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_004896.1|ensembl:ENSG00000117592(gene)|ensembl:ENST00000340385(transcript)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:0102567"|go:"GO:0102568"|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|rcsb pdb:1PRX|rcsb pdb:5B6M|rcsb pdb:5B6N|reactome:R-HSA-3299685|reactome:R-HSA-6798695|go:"GO:0042744"(hydrogen peroxide catabolic process) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:ZMsHgrAJf0VJiCELzo+zSi8Ji+49606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q15366 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-945799|uniprotkb:Q6PKG5|intact:EBI-9640573|uniprotkb:Q6IPF4|uniprotkb:B4DXP5|intact:EBI-2555278|uniprotkb:A8K7X6|uniprotkb:F8VYL7|uniprotkb:Q32Q82|uniprotkb:Q68Y55|uniprotkb:I6L8F9|uniprotkb:Q59HD4|uniprotkb:G3V0E8|ensembl:ENSP00000408949 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pcbp2_human(display_long)|uniprotkb:PCBP2(gene name)|psi-mi:PCBP2(display_short)|uniprotkb:Alpha-CP2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001122383.1|refseq:NP_114366.1|refseq:NP_005007.2|refseq:NP_001092090.1|refseq:NP_001122384.1|refseq:NP_001122385.1|refseq:NP_001122386.1|dip:DIP-58934N|ensembl:ENSG00000197111(gene)|ensembl:ENST00000439930(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0051607"(defense response to virus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15366|rcsb pdb:2AXY|rcsb pdb:2JZX|rcsb pdb:2P2R|rcsb pdb:2PQU|rcsb pdb:2PY9|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-936440 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:KWabGhH+pfSX5k0vzs3SXH8Agaw9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P08238 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:wOsW7C10v2oMsM+REE38K6PAan09606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P38159 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-743526|ensembl:ENSP00000359645|uniprotkb:Q5JQ67|uniprotkb:Q969R3|uniprotkb:D3DWH0|uniprotkb:E9PG86|uniprotkb:Q8N8Y7|uniprotkb:B4E3U4 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:rbmx_human(display_long)|uniprotkb:Glycoprotein p43(gene name synonym)|uniprotkb:RBMX(gene name)|psi-mi:RBMX(display_short)|uniprotkb:HNRPG(gene name synonym)|uniprotkb:RBMXP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000147274(gene)|ensembl:ENST00000320676(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P38159|rcsb pdb:2MB0|rcsb pdb:2MKS|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_002130.2|refseq:NP_001158275.1|dip:DIP-34447N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:ocCkdy9PxjeVLUQf0tMVCEhFfO89606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P31946 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P00558 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-709599|uniprotkb:A8K4W6|uniprotkb:Q5J7W1|uniprotkb:Q6IBT6|uniprotkb:Q8NI87|uniprotkb:B7Z7A9|ensembl:ENSP00000362413 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pgk1_human(display_long)|uniprotkb:Primer recognition protein 2(gene name synonym)|uniprotkb:Cell migration-inducing gene 10 protein(gene name synonym)|uniprotkb:PGK1(gene name)|psi-mi:PGK1(display_short)|uniprotkb:PGKA(gene name synonym)|uniprotkb:OK/SW-cl.110(orf name)|uniprotkb:MIG10(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_000282.1|dip:DIP-33679N|ensembl:ENSG00000102144(gene)|ensembl:ENST00000373316(transcript)|go:"GO:0004618"(phosphoglycerate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031639"(plasminogen activation)|go:"GO:0043531"(ADP binding)|go:"GO:0045121"(membrane raft)|go:"GO:0047134"("protein-disulfide reductase (NAD(P)) activity")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001576(Phosphoglycerate kinase)|interpro:IPR015824(Phosphoglycerate kinase, N-terminal)|interpro:IPR015911(Phosphoglycerate kinase, conserved site)|interpro:IPR036043|mint:P00558|rcsb pdb:2WZB|rcsb pdb:2WZC|rcsb pdb:2WZD|rcsb pdb:2X13|rcsb pdb:2X14|rcsb pdb:2X15|rcsb pdb:2XE6|rcsb pdb:2XE7|rcsb pdb:2XE8|rcsb pdb:2Y3I|rcsb pdb:2YBE|rcsb pdb:2ZGV|rcsb pdb:3C39|rcsb pdb:3C3A|rcsb pdb:3C3B|rcsb pdb:3C3C|rcsb pdb:3ZOZ|rcsb pdb:4AXX|rcsb pdb:4O33|rcsb pdb:5M1R|rcsb pdb:5M3U|rcsb pdb:5M6Z|rcsb pdb:5MXM|rcsb pdb:5NP8|rcsb pdb:5O7D|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:fkyBDnIx/ii6vfJjWJsxWi0piOQ9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q13151 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-724092|ensembl:ENSP00000316042|intact:EBI-1043661|uniprotkb:Q6IB18 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:roa0_human(display_long)|uniprotkb:HNRPA0(gene name synonym)|uniprotkb:HNRNPA0(gene name)|psi-mi:HNRNPA0(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_006796.1|ensembl:ENSG00000177733(gene)|ensembl:ENST00000314940(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006954"(inflammatory response)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034801|interpro:IPR035979|mint:Q13151|reactome:R-HSA-72163|reactome:R-HSA-72203 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:buyQxR8FLxd4N6jRhwVsroeGrBw9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P06733 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:RmP7cr55H8ylcgBOEyivwljIE+09606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P36873 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-356283|ensembl:ENSP00000335084 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pp1g_human(display_long)|uniprotkb:PPP1CC(gene name)|psi-mi:PPP1CC(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0004721"(phosphoprotein phosphatase activity)|ensembl:ENSG00000186298(gene)|ensembl:ENST00000335007(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0043197"(dendritic spine)|interpro:IPR029052|interpro:IPR031675|interpro:IPR037981|mint:P36873|rcsb pdb:1IT6|rcsb pdb:1JK7|rcsb pdb:1U32|rcsb pdb:2BCD|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|rcsb pdb:2BDX|rcsb pdb:4UT2|rcsb pdb:4UT3|go:"GO:0046872"(metal ion binding)|rcsb pdb:5INB|go:"GO:0047485"(protein N-terminus binding)|rcsb pdb:5J28|go:"GO:0051301"(cell division)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098793"(presynapse)|reactome:R-HSA-141444|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-9648025|reactome:R-HSA-9660537|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-400253|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-68877|refseq:NP_001231903.1|refseq:NP_002701.1|dip:DIP-749N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:SyjV/4d9V8lV/BXub2KESPKvupA9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:O43390 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-713419|uniprotkb:S4R3J4|uniprotkb:Q5TEH1|ensembl:ENSP00000304405|ensembl:ENSP00000363741|ensembl:ENSP00000489252|ensembl:ENSP00000489371|uniprotkb:Q9BV64|uniprotkb:Q2L7G6 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpr_human(display_long)|uniprotkb:HNRPR(gene name synonym)|uniprotkb:HNRNPR(gene name)|psi-mi:HNRNPR(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001095868.1|refseq:XP_005245768.1|ensembl:ENSG00000125944(gene)|ensembl:ENSG00000282958(gene)|ensembl:ENST00000302271(transcript)|ensembl:ENST00000374612(transcript)|ensembl:ENST00000634263(transcript)|ensembl:ENST00000634766(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043679"(axon terminus)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034411|interpro:IPR035979|mint:O43390|rcsb pdb:2DK2|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR041337|refseq:NP_005817.1|refseq:XP_011538773.1|refseq:NP_001284549.1|refseq:XP_016855497.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:UiOaRbnMd1S2FthR4RWltyq6xT49606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P62258 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P04406 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-354056|uniprotkb:P00354|uniprotkb:Q53X65|uniprotkb:E7EUT4|ensembl:ENSP00000229239|ensembl:ENSP00000380068|ensembl:ENSP00000380070 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:g3p_human(display_long)|uniprotkb:GAPDH(gene name)|psi-mi:GAPDH(display_short)|uniprotkb:OK/SW-cl.12(orf name)|uniprotkb:CDABP0047(orf name)|uniprotkb:GAPD(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_002037.2|refseq:NP_001243728.1|refseq:NP_001276674.1|refseq:NP_001276675.1|dip:DIP-32521N|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P04406|rcsb pdb:1U8F|rcsb pdb:1ZNQ|rcsb pdb:2FEH|rcsb pdb:3GPD|rcsb pdb:4WNC|rcsb pdb:4WNI|rcsb pdb:6ADE|rcsb pdb:6M61|rcsb pdb:6YND|rcsb pdb:6YNE|rcsb pdb:6YNF|rcsb pdb:6YNH|reactome:R-HSA-70171|reactome:R-HSA-70263|rcsb pdb:6IQ6|ensembl:ENSG00000111640(gene)|ensembl:ENST00000229239(transcript)|ensembl:ENST00000396859(transcript)|ensembl:ENST00000396861(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0031640"(killing of cells of another organism) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:9YENN/dfKl/d0tJtfFyQp2o8eAc9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P62937 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-437708|uniprotkb:P05092|uniprotkb:Q3KQW3|uniprotkb:Q6IBU5|uniprotkb:Q96IX3|uniprotkb:Q9BRU4|uniprotkb:Q9BTY9|uniprotkb:Q9UC61|uniprotkb:Q567Q0|ensembl:ENSP00000419425|uniprotkb:A8K220 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ppia_human(display_long)|uniprotkb:Cyclophilin A(gene name synonym)|uniprotkb:Cyclosporin A-binding protein(gene name synonym)|uniprotkb:PPIA(gene name)|psi-mi:PPIA(display_short)|uniprotkb:CYPA(gene name synonym)|uniprotkb:Rotamase A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_066953.1|interpro:IPR029000|mint:P62937|rcsb pdb:1AK4|rcsb pdb:1AWQ|rcsb pdb:1AWR|rcsb pdb:1AWS|rcsb pdb:1AWT|rcsb pdb:1AWU|rcsb pdb:1AWV|rcsb pdb:1BCK|rcsb pdb:1CWA|rcsb pdb:1CWB|rcsb pdb:1CWC|rcsb pdb:1CWF|rcsb pdb:1CWH|rcsb pdb:1CWI|rcsb pdb:1CWJ|rcsb pdb:1CWK|rcsb pdb:1CWL|rcsb pdb:1CWM|interpro:IPR024936|rcsb pdb:1CWO|rcsb pdb:1FGL|rcsb pdb:2N0T|rcsb pdb:2RMA|rcsb pdb:1M63|rcsb pdb:2RMB|rcsb pdb:2X25|rcsb pdb:2X2A|rcsb pdb:2X2C|rcsb pdb:2X2D|rcsb pdb:1M9C|rcsb pdb:1M9D|rcsb pdb:1M9E|rcsb pdb:2XGY|rcsb pdb:3CYH|rcsb pdb:3CYS|rcsb pdb:3K0M|rcsb pdb:3K0N|rcsb pdb:3K0O|rcsb pdb:3K0P|rcsb pdb:3K0Q|rcsb pdb:3K0R|rcsb pdb:3ODI|rcsb pdb:3ODL|rcsb pdb:1M9F|rcsb pdb:3RDD|rcsb pdb:1M9X|rcsb pdb:1M9Y|rcsb pdb:4CYH|rcsb pdb:4IPZ|rcsb pdb:4N1M|rcsb pdb:4N1N|rcsb pdb:1MF8|rcsb pdb:4N1O|rcsb pdb:4N1P|rcsb pdb:4N1Q|rcsb pdb:1MIK|rcsb pdb:1NMK|rcsb pdb:1OCA|rcsb pdb:1RMH|rcsb pdb:1VBS|rcsb pdb:1VBT|rcsb pdb:1W8L|rcsb pdb:1W8M|rcsb pdb:1W8V|rcsb pdb:1YND|rcsb pdb:1ZKF|rcsb pdb:2ALF|rcsb pdb:2CPL|rcsb pdb:2CYH|rcsb pdb:2MS4|rcsb pdb:2MZU|rcsb pdb:4N1R|rcsb pdb:4N1S|rcsb pdb:4YUG|rcsb pdb:4YUH|refseq:NP_001287910.1|reactome:R-HSA-210991|reactome:R-HSA-6798695|reactome:R-HSA-8950505|reactome:R-HSA-2025928|ensembl:ENSG00000196262(gene)|ensembl:ENST00000468812(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006915"(apoptotic process)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016020"(membrane)|go:"GO:0019076"(viral release from host cell)|go:"GO:0030168"(platelet activation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0031982"(vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046790"(virion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060352"(cell adhesion molecule production)|go:"GO:0061944"(negative regulation of protein K48-linked ubiquitination)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903901"(negative regulation of viral life cycle)|go:"GO:1904399"(heparan sulfate binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|go:"GO:0005178"(integrin binding)|rcsb pdb:4YUI|rcsb pdb:4YUJ|rcsb pdb:4YUK|rcsb pdb:4YUL|rcsb pdb:4YUM|rcsb pdb:4YUN|rcsb pdb:4YUO|rcsb pdb:4YUP|rcsb pdb:5CYH|rcsb pdb:5F66|rcsb pdb:5FJB|rcsb pdb:5KUL|rcsb pdb:5KUN|rcsb pdb:5KUO|rcsb pdb:5KUQ|rcsb pdb:5KUR|rcsb pdb:5KUS|rcsb pdb:5KUU|rcsb pdb:5KUV|rcsb pdb:5KUW|rcsb pdb:5KUZ|rcsb pdb:5KV0|rcsb pdb:5KV1|rcsb pdb:5KV2|rcsb pdb:5KV3|rcsb pdb:5KV4|rcsb pdb:5KV5|rcsb pdb:5KV6|rcsb pdb:5KV7|rcsb pdb:5LUD|rcsb pdb:5NOQ|rcsb pdb:5NOR|rcsb pdb:5NOT|rcsb pdb:5NOU|rcsb pdb:5NOV|rcsb pdb:5NOW|rcsb pdb:5NOX|rcsb pdb:5NOY|rcsb pdb:5NOZ|rcsb pdb:5T9U|rcsb pdb:5T9W|rcsb pdb:5T9Z|rcsb pdb:5TA2|rcsb pdb:5TA4|rcsb pdb:5WC7|rcsb pdb:6BTA|rcsb pdb:6GJI|rcsb pdb:6GJJ|rcsb pdb:6GJL|rcsb pdb:6GJM|rcsb pdb:6GJN|rcsb pdb:6GJP|rcsb pdb:6GJR|rcsb pdb:6GJY|rcsb pdb:6GS6|rcsb pdb:6I42|rcsb pdb:6U5C|rcsb pdb:6U5D|rcsb pdb:6U5E|rcsb pdb:6U5G|rcsb pdb:6X3R|rcsb pdb:6X3Y|rcsb pdb:5NOS|rcsb pdb:6X4N|rcsb pdb:6X4O|rcsb pdb:6X4P|rcsb pdb:6X4Q|rcsb pdb:6Y9V|rcsb pdb:6Y9W|rcsb pdb:6Y9X|rcsb pdb:6Y9Y|rcsb pdb:6Y9Z|rcsb pdb:6ZDJ|rcsb pdb:7ABT|reactome:R-HSA-114608|reactome:R-HSA-162585|reactome:R-HSA-162588|reactome:R-HSA-162592|reactome:R-HSA-162594|reactome:R-HSA-164516|reactome:R-HSA-164525|reactome:R-HSA-173107|rcsb pdb:6X4M|reactome:R-HSA-175474|reactome:R-HSA-180689|dip:DIP-6080N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:dr4EVxcO+sqTPBqsQcydRn+rHoo9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P63241 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-373150|uniprotkb:P10159|uniprotkb:Q16182|uniprotkb:Q7L7L3|uniprotkb:Q7Z4L1|uniprotkb:Q9D0G2|uniprotkb:A8K9A0|uniprotkb:D3DTP2|ensembl:ENSP00000336776|ensembl:ENSP00000390677|ensembl:ENSP00000396073|ensembl:ENSP00000458269|ensembl:ENSP00000459196|ensembl:ENSP00000459611|ensembl:ENSP00000499855|ensembl:ENSP00000499995|ensembl:ENSP00000500414|ensembl:ENSP00000500624|ensembl:ENSP00000500717|ensembl:ENSP00000500847 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:if5a1_human(display_long)|uniprotkb:EIF5A(gene name)|psi-mi:EIF5A(display_short)|uniprotkb:Eukaryotic initiation factor 5A isoform 1(gene name synonym)|uniprotkb:eIF-4D(gene name synonym)|uniprotkb:Rev-binding factor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001137232.1|refseq:NP_001137233.1|refseq:NP_001137234.1|refseq:NP_001961.1|refseq:XP_005256566.1|ensembl:ENSG00000132507(gene)|ensembl:ENSG00000288145(gene)|ensembl:ENST00000336458(transcript)|ensembl:ENST00000416016(transcript)|ensembl:ENST00000419711(transcript)|ensembl:ENST00000571955(transcript)|ensembl:ENST00000573542(transcript)|ensembl:ENST00000576930(transcript)|ensembl:ENST00000672250(transcript)|ensembl:ENST00000672755(transcript)|ensembl:ENST00000673099(transcript)|ensembl:ENST00000673210(transcript)|ensembl:ENST00000673259(transcript)|ensembl:ENST00000673304(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0098586"(cellular response to virus)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001884("Eukaryotic initiation factor 5A hypusine (eIF-5A)")|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR019769|interpro:IPR020189|mint:P63241|rcsb pdb:1FH4|rcsb pdb:3CPF|rcsb pdb:5DLQ|reactome:R-HSA-204626 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:/smk81DLs+XvrqXmIZpfvdHHauk9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P27348 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081|ensembl:ENSP00000371267 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_006817.1|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|ensembl:ENSG00000134308(gene)|ensembl:ENST00000238081(transcript)|ensembl:ENST00000381844(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|dip:DIP-27584N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P29966 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1047781|uniprotkb:E1P560|uniprotkb:Q2LA83|uniprotkb:Q5TDB7|ensembl:ENSP00000478061 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:marcs_human(display_long)|uniprotkb:Protein kinase C substrate, 80 kDa protein, light chain(gene name synonym)|uniprotkb:MARCKS(gene name)|psi-mi:MARCKS(display_short)|uniprotkb:MACS(gene name synonym)|uniprotkb:PRKCSL(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_002347.5|ensembl:ENSG00000277443(gene)|ensembl:ENST00000612661(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042585"(germinal vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002101(Myristoylated alanine-rich C-kinase substrate MARCKS)|mint:P29966|reactome:R-HSA-399997 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:28v6sOqwULr0AvfJr7yAal9Yh1g9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P09651 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352662|uniprotkb:Q3MIB7|uniprotkb:Q6PJZ7|ensembl:ENSP00000341826|ensembl:ENSP00000503610|uniprotkb:A8K4Z8|intact:EBI-2556572 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:roa1_human(display_long)|uniprotkb:HNRNPA1(gene name)|psi-mi:HNRNPA1(display_short)|uniprotkb:HNRPA1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:Single-strand RNA-binding protein(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_002127.1|refseq:NP_112420.1|ensembl:ENSG00000135486(gene)|ensembl:ENST00000340913(transcript)|ensembl:ENST00000677210(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|rcsb pdb:2LYV|rcsb pdb:2UP1|rcsb pdb:4YOE|rcsb pdb:5MPG|rcsb pdb:5MPL|rcsb pdb:5ZGD|rcsb pdb:5ZGL|rcsb pdb:6BXX|rcsb pdb:6DCL|rcsb pdb:6J60|rcsb pdb:7BX7|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035198"(miRNA binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051170"(import into nucleus)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR034845|interpro:IPR035979|mint:P09651|rcsb pdb:1HA1|rcsb pdb:1L3K|rcsb pdb:1PGZ|rcsb pdb:1PO6|rcsb pdb:1U1K|rcsb pdb:1U1L|rcsb pdb:1U1M|rcsb pdb:1U1N|rcsb pdb:1U1O|rcsb pdb:1U1P|rcsb pdb:1U1Q|rcsb pdb:1U1R|rcsb pdb:1UP1|rcsb pdb:2H4M|refseq:XP_005268883.1|dip:DIP-29338N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:ECXjsLRVtNc/aOw90tEFxowHc6c9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P22234 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q6IS14 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-6151859|ensembl:ENSP00000430706 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:if5al_human(display_long)|uniprotkb:Eukaryotic initiation factor 5A isoform 1-like(gene name synonym)|uniprotkb:EIF5AL1(gene name)|psi-mi:EIF5AL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001093162.1|ensembl:ENSG00000253626(gene)|ensembl:ENST00000520547(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0051028"(mRNA transport)|interpro:IPR001884("Eukaryotic initiation factor 5A hypusine (eIF-5A)")|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR019769|interpro:IPR020189 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:sV7lnYqekOx0EisZGSpo8EWAl+09606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q9NZI8 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1053892|uniprotkb:C9JT33|ensembl:ENSP00000290341 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:if2b1_human(display_long)|uniprotkb:ZBP1(gene name synonym)|uniprotkb:IGF-II mRNA-binding protein 1(gene name synonym)|uniprotkb:Coding region determinant-binding protein(gene name synonym)|uniprotkb:VICKZ family member 1(gene name synonym)|uniprotkb:IGF2BP1(gene name)|psi-mi:IGF2BP1(display_short)|uniprotkb:Zipcode-binding protein 1(gene name synonym)|uniprotkb:CRDBP(gene name synonym)|uniprotkb:VICKZ1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_006537.3|refseq:NP_001153895.1|ensembl:ENSG00000159217(gene)|ensembl:ENST00000290341(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007399"(nervous system development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010610"(regulation of mRNA stability involved in response to stress)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022013"(pallium cell proliferation in forebrain)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0140059"(dendrite arborization)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034837|interpro:IPR034842|interpro:IPR035979|interpro:IPR036612|mint:Q9NZI8|rcsb pdb:3KRM|rcsb pdb:6QEY|reactome:R-HSA-428359|reactome:R-HSA-5687128|dip:DIP-38139N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:3Ps/PWWYr0WpYcx3G/AOiQEj+vc9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P62140 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352350|uniprotkb:P37140|uniprotkb:Q5U087|uniprotkb:Q6FG45|uniprotkb:D6W565|uniprotkb:B2R5V4|ensembl:ENSP00000296122|ensembl:ENSP00000351298|ensembl:ENSP00000378769 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pp1b_human(display_long)|uniprotkb:PPP1CB(gene name)|psi-mi:PPP1CB(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_002700.1|refseq:NP_996759.1|ensembl:ENSG00000213639(gene)|ensembl:ENST00000296122(transcript)|ensembl:ENST00000358506(transcript)|ensembl:ENST00000395366(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016791"(phosphatase activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0046872"(metal ion binding)|go:"GO:0050115"(myosin-light-chain-phosphatase activity)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|mint:P62140|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-2565942|reactome:R-HSA-400253|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-5673000|reactome:R-HSA-9660537|dip:DIP-33220N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:VtNJVyimeiEuRDDWtGswTqoSOH89606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:O60506 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1024357|uniprotkb:Q53H05|uniprotkb:Q5TCG2|uniprotkb:Q8IW78|uniprotkb:Q8N599|uniprotkb:Q96LC1|uniprotkb:Q96LC2|uniprotkb:Q9Y583|uniprotkb:Q5TCG3|uniprotkb:E1P501|uniprotkb:E1P502|ensembl:ENSP00000358635|ensembl:ENSP00000503783|ensembl:ENSP00000504706 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpq_human(display_long)|uniprotkb:Synaptotagmin-binding, cytoplasmic RNA-interacting protein(gene name synonym)|uniprotkb:Glycine- and tyrosine-rich RNA-binding protein(gene name synonym)|uniprotkb:NS1-associated protein 1(gene name synonym)|uniprotkb:SYNCRIP(gene name)|psi-mi:SYNCRIP(display_short)|uniprotkb:HNRPQ(gene name synonym)|uniprotkb:NSAP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001153145.1|refseq:NP_001153146.1|refseq:NP_001153147.1|refseq:NP_001240700.1|refseq:NP_001153148.1|refseq:NP_001153149.1|refseq:NP_006363.4|ensembl:ENSG00000135316(gene)|ensembl:ENST00000369622(transcript)|ensembl:ENST00000676688(transcript)|ensembl:ENST00000678355(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034544|interpro:IPR034548|interpro:IPR035979|interpro:IPR041337|mint:O60506|rcsb pdb:2DGU|rcsb pdb:2MXT|rcsb pdb:2NBB|rcsb pdb:6KOR|refseq:XP_016865667.1|refseq:XP_005248694.1|dip:DIP-35540N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:2rDkXIp/wWzTOoVtN7Bd3uqZo689606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P51991 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1050760|uniprotkb:Q53RW7|uniprotkb:Q6URK5|uniprotkb:D3DPF4|ensembl:ENSP00000376309|ensembl:ENSP00000416340|ensembl:ENSP00000503593|ensembl:ENSP00000504135|ensembl:ENSP00000504152 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:roa3_human(display_long)|uniprotkb:HNRPA3(gene name synonym)|uniprotkb:HNRNPA3(gene name)|psi-mi:HNRNPA3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_919223.1|refseq:NP_001317178.1|ensembl:ENSG00000170144(gene)|ensembl:ENST00000392524(transcript)|ensembl:ENST00000435711(transcript)|ensembl:ENST00000676629(transcript)|ensembl:ENST00000678111(transcript)|ensembl:ENST00000679159(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0051028"(mRNA transport)|go:"GO:0051033"(RNA transmembrane transporter activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034513|interpro:IPR034516|interpro:IPR035979|mint:P51991|reactome:R-HSA-72163|reactome:R-HSA-72203 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:bbg0nIdhEHomcwtgZhT2yHy7+nU9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q14103 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-299674|ensembl:ENSP00000313199|uniprotkb:P07029|uniprotkb:Q01858|uniprotkb:Q14100|uniprotkb:Q14101|uniprotkb:Q14102|uniprotkb:Q4W5A1|uniprotkb:A8K9J2|uniprotkb:Q9UCE8|uniprotkb:Q9UCE9 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpd_human(display_long)|uniprotkb:HNRNPD(gene name)|psi-mi:HNRNPD(display_short)|uniprotkb:AUF1(gene name synonym)|uniprotkb:HNRPD(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000138668(gene)|ensembl:ENST00000313899(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021549"(cerebellum development)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:1901355"(response to rapamycin)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904383"(response to sodium phosphate)|go:"GO:1904586"(cellular response to putrescine)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990828"(hepatocyte dedifferentiation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR035979|mint:Q14103|rcsb pdb:1HD0|rcsb pdb:1HD1|rcsb pdb:1IQT|rcsb pdb:1WTB|rcsb pdb:1X0F|rcsb pdb:2Z5N|rcsb pdb:5IM0|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|reactome:R-HSA-450408|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:NP_001003810.1|refseq:NP_002129.2|refseq:NP_112737.1|refseq:NP_112738.1|dip:DIP-31163N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:LrC0nOpN6jGn3WELs5NEOccNPnw9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q7Z406 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-355595|uniprotkb:Q5CZ75|uniprotkb:Q6XYE4|uniprotkb:Q76B62|uniprotkb:Q8WV23|uniprotkb:Q96I22|uniprotkb:Q9BT27|uniprotkb:Q9BW35|uniprotkb:Q9H882|uniprotkb:B0I1S2|ensembl:ENSP00000366169|ensembl:ENSP00000472819|uniprotkb:C3TTN4 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:myh14_human(display_long)|uniprotkb:MYH14(gene name)|psi-mi:MYH14(display_short)|uniprotkb:KIAA2034(gene name synonym)|uniprotkb:FP17425(orf name)|uniprotkb:Myosin heavy chain 14(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIc(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIc(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001070654.1|refseq:NP_001139281.1|refseq:NP_079005.3|refseq:XP_011525625.1|ensembl:ENSG00000105357(gene)|ensembl:ENST00000376970(transcript)|ensembl:ENST00000596571(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001725"(stress fiber)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030426"(growth cone)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0042641"(actomyosin)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097513"(myosin II filament)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:Q7Z406|rcsb pdb:5I4E|rcsb pdb:5JLH|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|interpro:IPR002928(Myosin tail)|refseq:XP_006723449.1|dip:DIP-33170N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:6aY3HPa5DIY5UadiOTTh/uSPi/M9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P80723 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-358583|uniprotkb:D3DTD5|uniprotkb:O43596|uniprotkb:Q5U0S0|uniprotkb:Q9BWA5|uniprotkb:B4DJA8|ensembl:ENSP00000319281|ensembl:ENSP00000482066 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:basp1_human(display_long)|uniprotkb:BASP1(gene name)|psi-mi:BASP1(display_short)|uniprotkb:NAP22(gene name synonym)|uniprotkb:Neuronal axonal membrane protein NAP-22(gene name synonym)|uniprotkb:22 kDa neuronal tissue-enriched acidic protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_006308.3|refseq:NP_001258535.1|ensembl:ENSG00000176788(gene)|ensembl:ENST00000322611(transcript)|ensembl:ENST00000616743(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0008406"(gonad development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030054"(cell junction)|go:"GO:0030426"(growth cone)|go:"GO:0031982"(vesicle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0060421"(positive regulation of heart growth)|go:"GO:0060539"(diaphragm development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072075"(metanephric mesenchyme development)|go:"GO:0072112"(glomerular visceral epithelial cell differentiation)|go:"GO:2001076"(positive regulation of metanephric ureteric bud development)|interpro:IPR008408(Brain acid soluble protein 1)|mint:P80723|reactome:R-HSA-9035034 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:X+L20HKimV3J+vLnQljg+x78+e09606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:O75369 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352089|intact:EBI-1754974|uniprotkb:Q13706|uniprotkb:Q59EC2|uniprotkb:Q6MZJ1|uniprotkb:Q8WXS9|uniprotkb:Q8WXT0|uniprotkb:Q8WXT1|uniprotkb:Q8WXT2|uniprotkb:Q9NRB5|uniprotkb:B2ZZ84|uniprotkb:Q9NT26|uniprotkb:Q9UEV9|intact:EBI-1960054|uniprotkb:C9JKE6|uniprotkb:B2ZZ85|uniprotkb:C9JMC4|ensembl:ENSP00000295956|uniprotkb:B2ZZ83|uniprotkb:Q60FE7|uniprotkb:Q8WXT3 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:flnb_human(display_long)|uniprotkb:FLNB(gene name)|psi-mi:FLNB(display_short)|uniprotkb:FLN1L(gene name synonym)|uniprotkb:FLN3(gene name synonym)|uniprotkb:TABP(gene name synonym)|uniprotkb:TAP(gene name synonym)|uniprotkb:Beta-filamin(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:Thyroid autoantigen(gene name synonym)|uniprotkb:Truncated actin-binding protein(gene name synonym)|uniprotkb:ABP-280 homolog(gene name synonym)|uniprotkb:ABP-278(gene name synonym)|uniprotkb:Filamin-3(gene name synonym)|uniprotkb:Filamin homolog 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001157791.1|refseq:NP_001448.2|go:"GO:0003334"(keratinocyte development)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045296"(cadherin binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR029874|interpro:IPR036872|interpro:IPR044801|mint:O75369|rcsb pdb:2DI8|rcsb pdb:2DI9|rcsb pdb:2DIA|rcsb pdb:2DIB|rcsb pdb:2DIC|rcsb pdb:2DJ4|rcsb pdb:2DLG|rcsb pdb:2DMB|rcsb pdb:2DMC|rcsb pdb:2E9I|rcsb pdb:2E9J|rcsb pdb:2EE6|rcsb pdb:2EE9|rcsb pdb:2EEA|rcsb pdb:2EEB|rcsb pdb:2EEC|rcsb pdb:2EED|rcsb pdb:2WA5|rcsb pdb:2WA6|rcsb pdb:2WA7|rcsb pdb:3FER|rcsb pdb:4B7L|rcsb pdb:5DCP|reactome:R-HSA-1169408|ensembl:ENSG00000136068(gene)|ensembl:ENST00000295956(transcript)|go:"GO:0001725"(stress fiber)|refseq:NP_001157789.1|refseq:NP_001157790.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:lsf6C/Vg0io7UhUi1Kapgwp0p5E9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P27797 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1049597|uniprotkb:Q6IAT4|uniprotkb:Q9UDG2|ensembl:ENSP00000320866|ensembl:ENSP00000466037 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:calr_human(display_long)|uniprotkb:CRP55(gene name synonym)|uniprotkb:Calregulin(gene name synonym)|uniprotkb:HACBP(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:grp60(gene name synonym)|uniprotkb:CALR(gene name)|psi-mi:CALR(display_short)|uniprotkb:CRTC(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_004334.1|ensembl:ENSG00000179218(gene)|ensembl:ENST00000316448(transcript)|ensembl:ENST00000586967(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0002502"(peptide antigen assembly with MHC class I protein complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005506"(iron ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042277"(peptide binding)|go:"GO:0042493"|go:"GO:0042562"(hormone binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060473"(cortical granule)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0090398"(cellular senescence)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR009169(Calreticulin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27797|rcsb pdb:2CLR|rcsb pdb:3DOW|rcsb pdb:3POS|rcsb pdb:3POW|rcsb pdb:5LK5|rcsb pdb:5V90|rcsb pdb:6ENY|reactome:R-HSA-1236974|reactome:R-HSA-168316|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-381183|reactome:R-HSA-901042|reactome:R-HSA-983170|dip:DIP-104N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:FSPSiiN6YTaETDyAWwAP3wV6zRI9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P68104 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P62158 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P67809 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P06576 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-356231|ensembl:ENSP00000262030|uniprotkb:Q14283|uniprotkb:A8K4X0|intact:EBI-2322803 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:atpb_human(display_long)|uniprotkb:ATP5F1B(gene name)|psi-mi:ATP5F1B(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:ATP5B(gene name synonym)|uniprotkb:ATPMB(gene name synonym)|uniprotkb:ATPSB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000110955(gene)|ensembl:ENST00000262030(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|interpro:IPR020003|interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|mint:P06576|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-2151201|reactome:R-HSA-8949613|go:"GO:0070062"(extracellular exosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|refseq:NP_001677.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:oLPUvG1tQkkzxzeAG6R0ZkZF+eg9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P10809 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352528|ensembl:ENSP00000340019|ensembl:ENSP00000373620|ensembl:ENSP00000396460|ensembl:ENSP00000402478|ensembl:ENSP00000412227|ensembl:ENSP00000412717|ensembl:ENSP00000414446|ensembl:ENSP00000503139|ensembl:ENSP00000503894|uniprotkb:Q38L19|uniprotkb:B2R5M6|uniprotkb:Q9UCR6|uniprotkb:B7Z712 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ch60_human(display_long)|uniprotkb:HSPD1(gene name)|psi-mi:HSPD1(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:P60 lymphocyte protein(gene name synonym)|uniprotkb:HuCHA60(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_002147.2|refseq:NP_955472.1|ensembl:ENSG00000144381(gene)|ensembl:ENST00000345042(transcript)|ensembl:ENST00000388968(transcript)|ensembl:ENST00000418022(transcript)|ensembl:ENST00000426480(transcript)|ensembl:ENST00000428204(transcript)|ensembl:ENST00000439605(transcript)|ensembl:ENST00000452200(transcript)|ensembl:ENST00000677913(transcript)|ensembl:ENST00000678761(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051604"(protein maturation)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P10809|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|rcsb pdb:7AZP|reactome:R-HSA-1268020|reactome:R-HSA-8869496|dip:DIP-58N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:syB2vt66Cpr2mJROfbxoPevoiRE9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:O00159 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-350423|uniprotkb:Q6NVJ7|intact:EBI-1045431|uniprotkb:Q86Y95|uniprotkb:Q4LE56|ensembl:ENSP00000496954 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:myo1c_human(display_long)|uniprotkb:MYO1C(gene name)|psi-mi:MYO1C(display_short)|uniprotkb:Myosin I beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0006605"(protein targeting)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0005829"(cytosol)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0038089"(positive regulation of cell migration by vascular endothelial growth factor signaling pathway)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|refseq:NP_001074248.1|refseq:NP_001074419.1|refseq:NP_203693.3|ensembl:ENSG00000197879(gene)|ensembl:ENST00000648651(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|interpro:IPR036961|mint:O00159|rcsb pdb:4BYF|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-5250924|reactome:R-HSA-9662360|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|reactome:R-HSA-9662361|reactome:R-HSA-9664422|dip:DIP-33109N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:g6wQN0OVKjd3T1kOebWFcqWNzNA9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P63104 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P15259 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-2511669|ensembl:ENSP00000297283 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:pgam2_human(display_long)|uniprotkb:PGAM2(gene name)|psi-mi:PGAM2(display_short)|uniprotkb:PGAMM(gene name synonym)|uniprotkb:Phosphoglycerate mutase isozyme M(gene name synonym)|uniprotkb:BPG-dependent PGAM 2(gene name synonym)|uniprotkb:Muscle-specific phosphoglycerate mutase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000164708(gene)|ensembl:ENST00000297283(transcript)|go:"GO:0004082"(bisphosphoglycerate mutase activity)|go:"GO:0004619"(phosphoglycerate mutase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046538"(2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity)|go:"GO:0046689"(response to mercury ion)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR005952(Phosphoglycerate mutase 1)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|reactome:R-HSA-70171|reactome:R-HSA-70263|go:"GO:0070062"(extracellular exosome)|refseq:NP_000281.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:vvkAsNcXn85pUpOvqy5JqF99n309606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P07437 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P60660 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-300817|uniprotkb:P16475|uniprotkb:P24572|uniprotkb:P24573|uniprotkb:Q12790|ensembl:ENSP00000446955|ensembl:ENSP00000448101|uniprotkb:Q6IAZ0|uniprotkb:Q6IPY5|uniprotkb:Q561V9 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:myl6_human(display_long)|uniprotkb:MYL6(gene name)|psi-mi:MYL6(display_short)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6(gene name synonym)|uniprotkb:Myosin light chain alkali 3(gene name synonym)|uniprotkb:Myosin light chain 3(gene name synonym)|uniprotkb:17 kDa myosin light chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000092841(gene)|ensembl:ENST00000548293(transcript)|ensembl:ENST00000550697(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016020"(membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P60660|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:NP_066299.2|refseq:NP_524147.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:LhE3NUqcuHlOla13C0vjnFZfzy89606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P61978 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-304185|intact:EBI-28971491|ensembl:ENSP00000317788|ensembl:ENSP00000353552|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q59F98|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62|uniprotkb:Q5T6W4|intact:EBI-3440248|uniprotkb:Q6IBN1 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:hnrpk_human(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000165119(gene)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000351839(transcript)|ensembl:ENST00000360384(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0002102"(podosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61978|rcsb pdb:1J5K|rcsb pdb:1KHM|rcsb pdb:1ZZI|rcsb pdb:1ZZJ|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9610379|rcsb pdb:1ZZK|refseq:NP_002131.2|refseq:NP_112552.1|refseq:NP_112553.1|ensembl:ENSP00000317788|ensembl:ENSP00000353552|ensembl:ENST00000376263|ensembl:ENSP00000365439|ensembl:ENST00000376281|ensembl:ENSP00000365458|refseq:NP_001305115.1|refseq:NP_001305116.1|refseq:NP_001305117.1|refseq:XP_016870157.1|refseq:XP_005252017.1|refseq:XP_005252020.1|refseq:XP_005252022.1|dip:DIP-31805N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P43243 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-352602|ensembl:ENSP00000378284|ensembl:ENSP00000482895|uniprotkb:Q9UHW0|uniprotkb:Q9UQ27|uniprotkb:D3DQC3|uniprotkb:B7ZAV5 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:matr3_human(display_long)|uniprotkb:KIAA0723(gene name synonym)|uniprotkb:MATR3(gene name)|psi-mi:MATR3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000015479(gene)|ensembl:ENST00000394805(transcript)|ensembl:ENST00000618441(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:P43243|refseq:NP_001181883.1|refseq:NP_001181884.1|refseq:NP_061322.2|refseq:NP_954659.1|refseq:NP_001181885.1|refseq:NP_001269207.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:3UZlyCZHgdr1SBgUctv9Ev7XBSQ9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P14174 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-372712|uniprotkb:A5Z1R8|uniprotkb:B2R4S3|uniprotkb:Q6FHV0|uniprotkb:Q2V4Y5|ensembl:ENSP00000215754|ensembl:ENSP00000482779 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:mif_human(display_long)|uniprotkb:MIF(gene name)|psi-mi:MIF(display_short)|uniprotkb:MMIF(gene name synonym)|uniprotkb:GLIF(gene name synonym)|uniprotkb:Phenylpyruvate tautomerase(gene name synonym)|uniprotkb:Glycosylation-inhibiting factor(gene name synonym)|uniprotkb:L-dopachrome tautomerase(gene name synonym)|uniprotkb:L-dopachrome isomerase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_002406.1|ensembl:ENST00000215754(transcript)|ensembl:ENST00000613839(transcript)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004167"(dopachrome isomerase activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|ensembl:ENSG00000276701(gene)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0010760"(negative regulation of macrophage chemotaxis)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031982"(vesicle)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|ensembl:ENSG00000240972(gene)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045087"(innate immune response)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050178"(phenylpyruvate tautomerase activity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001398(Macrophage migration inhibitory factor)|interpro:IPR014347(Tautomerase)|interpro:IPR019829|mint:P14174|rcsb pdb:1CGQ|rcsb pdb:1GCZ|rcsb pdb:1GD0|rcsb pdb:1GIF|rcsb pdb:1LJT|rcsb pdb:1MIF|rcsb pdb:1P1G|rcsb pdb:2OOH|rcsb pdb:2OOW|rcsb pdb:2OOZ|rcsb pdb:3B9S|rcsb pdb:3CE4|rcsb pdb:3DJH|rcsb pdb:3DJI|rcsb pdb:3HOF|rcsb pdb:3IJG|rcsb pdb:3IJJ|rcsb pdb:3JSF|rcsb pdb:3JSG|rcsb pdb:3JTU|rcsb pdb:3L5P|rcsb pdb:3L5R|rcsb pdb:3L5S|rcsb pdb:3L5T|rcsb pdb:3L5U|rcsb pdb:3L5V|rcsb pdb:3SMB|rcsb pdb:3SMC|rcsb pdb:3U18|rcsb pdb:3WNR|rcsb pdb:3WNS|rcsb pdb:3WNT|rcsb pdb:4ETG|rcsb pdb:4EUI|rcsb pdb:4EVG|rcsb pdb:4F2K|rcsb pdb:4GRN|rcsb pdb:4GRO|rcsb pdb:4GRP|rcsb pdb:4GRQ|rcsb pdb:4GRR|rcsb pdb:4GRU|rcsb pdb:4GUM|rcsb pdb:4K9G|rcsb pdb:4OSF|rcsb pdb:4OYQ|rcsb pdb:4P01|rcsb pdb:4P0H|rcsb pdb:4PKK|rcsb pdb:4PKZ|rcsb pdb:4PLU|rcsb pdb:4TRF|rcsb pdb:4TRU|rcsb pdb:4WR8|rcsb pdb:4WRB|rcsb pdb:4XX7|rcsb pdb:4XX8|rcsb pdb:4Z15|rcsb pdb:4Z1T|rcsb pdb:4Z1U|rcsb pdb:5B4O|rcsb pdb:5BS9|rcsb pdb:5BSC|rcsb pdb:5BSI|rcsb pdb:5BSJ|rcsb pdb:5EIZ|rcsb pdb:5HVS|rcsb pdb:5HVT|rcsb pdb:5HVV|rcsb pdb:5J7P|rcsb pdb:5J7Q|rcsb pdb:5UMJ|rcsb pdb:5UMK|rcsb pdb:5UZY|rcsb pdb:5V70|rcsb pdb:5V73|rcsb pdb:5XEJ|rcsb pdb:1CA7|rcsb pdb:6B1C|rcsb pdb:6B1K|rcsb pdb:6B2C|rcsb pdb:6BG6|rcsb pdb:6BG7|rcsb pdb:6CB5|rcsb pdb:6CBF|rcsb pdb:6CBG|rcsb pdb:6FVE|rcsb pdb:6FVH|rcsb pdb:6OY8|rcsb pdb:6OYB|rcsb pdb:6OYE|rcsb pdb:6OYG|rcsb pdb:6PEG|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-8950505|rcsb pdb:6CBH|dip:DIP-31137N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:Vk+Sfaz5c59y8dKKJ4Qn+7fjwvQ9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q5VTE0 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-877809 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ef1a3_human(display_long)|uniprotkb:EEF1A1P5(gene name)|psi-mi:EEF1A1P5(display_short)|uniprotkb:Eukaryotic elongation factor 1 A-like 3(gene name synonym)|uniprotkb:EEF1AL3(gene name synonym)|uniprotkb:Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR031157|reactome:R-HSA-156842|interpro:IPR027417 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:3t6tj3i+3CKTC1NsrHyBkeoRK789606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q7L2E3 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-1211456|uniprotkb:O94965|uniprotkb:Q7Z753|uniprotkb:Q96CH4|uniprotkb:Q9NUQ0|uniprotkb:A8K5F1|ensembl:ENSP00000392601|ensembl:ENSP00000405620|intact:EBI-21350949 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:dhx30_human(display_long)|uniprotkb:DHX30(gene name)|psi-mi:DHX30(display_short)|uniprotkb:KIAA0890(gene name synonym)|uniprotkb:DDX30(gene name synonym)|uniprotkb:DEAH box protein 30(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_055781.2|refseq:NP_619520.1|refseq:XP_011531796.1|refseq:XP_011531797.1|refseq:XP_016861406.1|ensembl:ENSG00000132153(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007417"(central nervous system development)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902775"(mitochondrial large ribosomal subunit assembly)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|mint:Q7L2E3|rcsb pdb:2DB2|ensembl:ENST00000445061(transcript)|ensembl:ENST00000446256(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:tb4GzZKLycraXS0NlVqj8reV3IQ9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P62306 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-356900|uniprotkb:A2VCR2|uniprotkb:Q15356|uniprotkb:Q6IBQ1|uniprotkb:Q6P4I0|uniprotkb:B2R498|ensembl:ENSP00000266735 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ruxf_human(display_long)|uniprotkb:SNRPF(gene name)|psi-mi:SNRPF(display_short)|uniprotkb:PBSCF(gene name synonym)|uniprotkb:Sm protein F(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_003086.1|ensembl:ENSG00000139343(gene)|ensembl:ENST00000266735(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|dip:DIP-31221N|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|interpro:IPR034100|mint:P62306|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:2RggXu+kFj6wG7gTmxRHOIRvXiM9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:Q05639 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-354943|ensembl:ENSP00000217182|uniprotkb:P54266|uniprotkb:Q0VGC7|uniprotkb:B5BUF3|uniprotkb:E1P5J1 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:ef1a2_human(display_long)|uniprotkb:EEF1A2(gene name)|psi-mi:EEF1A2(display_short)|uniprotkb:EEF1AL(gene name synonym)|uniprotkb:STN(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-2(gene name synonym)|uniprotkb:Statin-S1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSG00000101210(gene)|ensembl:ENST00000217182(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0090218"(positive regulation of lipid kinase activity)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:Q05639|rcsb pdb:3C5J|reactome:R-HSA-156842|refseq:NP_001949.1|dip:DIP-40060N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:vFXfcSRokxKo5RW0tRE1qEK0NKw9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:O00459 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-346930|uniprotkb:Q5EAT5|uniprotkb:Q9UPH9|intact:EBI-28974273|ensembl:ENSP00000222254 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:p85b_human(display_long)|uniprotkb:PIK3R2(gene name)|psi-mi:PIK3R2(display_short)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 ensembl:ENSP00000222254|refseq:NP_005018.1|dip:DIP-31811N|ensembl:ENSG00000105647(gene)|ensembl:ENST00000222254(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|rcsb pdb:6OX7|rcsb pdb:6U28|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-186763|reactome:R-HSA-198203|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|mint:O00459|rcsb pdb:2KT1|rcsb pdb:2XS6|rcsb pdb:3MTT|rcsb pdb:3O5Z|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-210993|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9013409 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:Ij0WS0eKPwShgFWQc7OEss7AcAU9606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03496 uniprotkb:P35580 intact:EBI-2547442|uniprotkb:Q20N32|uniprotkb:Q67267|uniprotkb:Q71QT3 intact:EBI-351758|intact:EBI-7850240|intact:MINT-8330016|uniprotkb:B2RWP9|uniprotkb:D3DTS1|uniprotkb:Q9BWG0|uniprotkb:Q12989|uniprotkb:Q16087|uniprotkb:Q149N3|ensembl:ENSP00000269243|uniprotkb:Q149N4|uniprotkb:Q6PK16|uniprotkb:F8VTL3|uniprotkb:Q4LE45 psi-mi:ns1_i34a1(display_long)|uniprotkb:NS(gene name)|psi-mi:NS(display_short)|uniprotkb:NS1A(gene name synonym) psi-mi:myh10_human(display_long)|uniprotkb:MYH10(gene name)|psi-mi:MYH10(display_short)|uniprotkb:Myosin heavy chain 10(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIb(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIb(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type B(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158649|imex:IM-17331-56 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR004208("Influenza B non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|rcsb pdb:2GX9|rcsb pdb:2ZKO|rcsb pdb:3L4Q|rcsb pdb:3O9Q|rcsb pdb:3O9R|rcsb pdb:3O9S|rcsb pdb:3O9T|rcsb pdb:3O9U|rcsb pdb:3RVC|rcsb pdb:5NT1|rcsb pdb:5NT2|refseq:NP_040984.1|reactome:R-HSA-168276|reactome:R-HSA-1169408|reactome:R-HSA-168315|reactome:R-HSA-168888|reactome:R-HSA-169131|reactome:R-HSA-192823|dip:DIP-29081N|reactome:R-HSA-5213460|reactome:R-HSA-9686347 refseq:NP_001243024.1|refseq:NP_001242941.1|refseq:NP_005955.3|ensembl:ENSG00000133026(gene)|ensembl:ENST00000269243(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016459"(myosin complex)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0042641"(actomyosin)|go:"GO:0043531"(ADP binding)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097513"(myosin II filament)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:P35580|rcsb pdb:4PD3|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:XP_016880169.1|refseq:XP_016880170.1|refseq:XP_016880171.1|dip:DIP-31110N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:W0UBADcb+1m7URzCs+MzRgb5ucU211044 rogid:iSHfJZbrWg1L+vSpu1n7RmTTNN49606 intact-crc:B655060F623B95BE|rigid:2u2RZmAZemlPu77/AcB9J/DuVa0 false mutation:103-103,38-38,106-106|tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:C3W5S7 uniprotkb:O00459 intact:EBI-6152135 intact:EBI-346930|uniprotkb:Q5EAT5|uniprotkb:Q9UPH9|intact:EBI-28974273|ensembl:ENSP00000222254 psi-mi:c3w5s7_i09a0(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:p85b_human(display_long)|uniprotkb:PIK3R2(gene name)|psi-mi:PIK3R2(display_short)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:641501(i09a0)|taxid:641501("Influenza A virus (strain swl A/California/04/2009 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158924|imex:IM-17331-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSP00000222254|refseq:NP_005018.1|dip:DIP-31811N|ensembl:ENSG00000105647(gene)|ensembl:ENST00000222254(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|rcsb pdb:6OX7|rcsb pdb:6U28|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-186763|reactome:R-HSA-198203|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|mint:O00459|rcsb pdb:2KT1|rcsb pdb:2XS6|rcsb pdb:3MTT|rcsb pdb:3O5Z|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-210993|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9013409 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:jt0jbAiZPt9QKdtbow8ibYQFIBg641501 rogid:Ij0WS0eKPwShgFWQc7OEss7AcAU9606 intact-crc:DC4E4C1336E16C5F|rigid:97sF1dExyA5vKTg51DWKIG3nsjM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:C3W5S7 uniprotkb:O14654 intact:EBI-6152135 intact:EBI-356594|ensembl:ENSP00000505547 psi-mi:c3w5s7_i09a0(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:641501(i09a0)|taxid:641501("Influenza A virus (strain swl A/California/04/2009 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158924|imex:IM-17331-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:jt0jbAiZPt9QKdtbow8ibYQFIBg641501 rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606 intact-crc:DC4E4C1336E16C5F|rigid:97sF1dExyA5vKTg51DWKIG3nsjM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:C3W5S7 uniprotkb:Q5JVF3 intact:EBI-6152135 intact:EBI-1051701|uniprotkb:A6NK09|uniprotkb:Q3ZCX1|uniprotkb:Q5TC57|uniprotkb:Q5TC58|uniprotkb:Q9H7K1|uniprotkb:Q9HBZ7|uniprotkb:Q9NUK6|uniprotkb:Q9NVY1|uniprotkb:Q9NW44|uniprotkb:Q9NWH3|ensembl:ENSP00000337405|ensembl:ENSP00000364626|ensembl:ENSP00000364628 psi-mi:c3w5s7_i09a0(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:pcid2_human(display_long)|uniprotkb:CSN12-like protein(gene name synonym)|uniprotkb:PCID2(gene name)|psi-mi:PCID2(display_short)|uniprotkb:HT004(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:641501(i09a0)|taxid:641501("Influenza A virus (strain swl A/California/04/2009 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158924|imex:IM-17331-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)")|go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus) refseq:NP_001120674.1|refseq:NP_001120675.1|refseq:NP_060856.2|refseq:NP_001245142.1|refseq:NP_001307584.1|refseq:NP_001307585.1|refseq:NP_001307586.1|refseq:NP_001307589.1|ensembl:ENSG00000126226(gene)|ensembl:ENST00000337344(transcript)|ensembl:ENST00000375477(transcript)|ensembl:ENST00000375479(transcript)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045579"(positive regulation of B cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048536"(spleen development)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071033"|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:2000117"(negative regulation of cysteine-type endopeptidase activity)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|rcsb pdb:3T5X|refseq:XP_016876153.1|dip:DIP-50497N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:jt0jbAiZPt9QKdtbow8ibYQFIBg641501 rogid:jFHv4Xifu2Qw/CzD5SKl3PgJpgE9606 intact-crc:DC4E4C1336E16C5F|rigid:97sF1dExyA5vKTg51DWKIG3nsjM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:Q6FI13 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-353620|uniprotkb:P20670|uniprotkb:B2R5F0|ensembl:ENSP00000358155|ensembl:ENSP00000475814 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:h2a2a_human(display_long)|uniprotkb:H2AC18(gene name)|psi-mi:H2AC18(display_short)|uniprotkb:H2AC19(gene name)|psi-mi:H2AC19(display_short)|uniprotkb:H2A-clustered histone 18(gene name synonym)|uniprotkb:H2A-clustered histone 19(gene name synonym)|uniprotkb:H2AFO(gene name synonym)|uniprotkb:HIST2H2AA(gene name synonym)|uniprotkb:HIST2H2AA3(gene name synonym)|uniprotkb:HIST2H2AA4(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/o(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV refseq:NP_001035807.1|refseq:NP_003507.1|ensembl:ENSG00000203812(gene)|ensembl:ENSG00000272196(gene)|ensembl:ENST00000369159(transcript)|ensembl:ENST00000607355(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6Y5D|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|dip:DIP-33167N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:PMuIm2XMN5q4wk+wYJ94mmnCe4w9606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:Q96KK5 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-6147668|ensembl:ENSP00000366679 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:h2a1h_human(display_long)|uniprotkb:H2AC12(gene name)|psi-mi:H2AC12(display_short)|uniprotkb:H2A-clustered histone 12(gene name synonym)|uniprotkb:HIST1H2AH(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:Histone H2A/s(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV refseq:NP_542163.1|dip:DIP-61699N|ensembl:ENSG00000274997(gene)|ensembl:ENST00000377459(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:Oa322n+evy8Cu0E9cWTEdYwQPKM9606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:P13051 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-1025947|uniprotkb:O00637|uniprotkb:O00719|uniprotkb:Q93028|uniprotkb:A8K5M6|uniprotkb:B2R8Y1|ensembl:ENSP00000242576 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:ung_human(display_long)|uniprotkb:UNG(gene name)|psi-mi:UNG(display_short)|uniprotkb:DGU(gene name synonym)|uniprotkb:UNG15(gene name synonym)|uniprotkb:UNG1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV refseq:NP_003353.1|refseq:NP_550433.1|ensembl:ENSG00000076248(gene)|ensembl:ENST00000242576(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045008"(depyrimidination)|go:"GO:0045190"(isotype switching)|go:"GO:0097510"(base-excision repair, AP site formation via deaminated base removal)|interpro:IPR002043(Uracil-DNA glycosylase)|interpro:IPR005122(Uracil-DNA glycosylase-like)|interpro:IPR018085|interpro:IPR036895|rcsb pdb:1AKZ|rcsb pdb:1DPU|rcsb pdb:1EMH|rcsb pdb:1EMJ|rcsb pdb:1Q3F|rcsb pdb:1SSP|rcsb pdb:1UGH|rcsb pdb:1YUO|rcsb pdb:2HXM|rcsb pdb:2OXM|rcsb pdb:2OYT|rcsb pdb:2SSP|rcsb pdb:3FCF|rcsb pdb:3FCI|rcsb pdb:3FCK|rcsb pdb:3FCL|rcsb pdb:3TKB|rcsb pdb:4SKN|rcsb pdb:5AYR|rcsb pdb:5JK7|rcsb pdb:6VBA|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|dip:DIP-24194N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:pjzUi17Vpmhp1JddThFwPvNhZCE9606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:P0C0S8 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:Q01082 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-351561|intact:EBI-1642531|uniprotkb:O60837|uniprotkb:Q16057|uniprotkb:Q53R99|uniprotkb:Q59ER3|uniprotkb:Q8IX99|uniprotkb:B2RP63|ensembl:ENSP00000349259 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:sptb2_human(display_long)|uniprotkb:SPTBN1(gene name)|psi-mi:SPTBN1(display_short)|uniprotkb:SPTB2(gene name synonym)|uniprotkb:Spectrin, non-erythroid beta chain 1(gene name synonym)|uniprotkb:Beta-II spectrin(gene name synonym)|uniprotkb:Fodrin beta chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV refseq:NP_003119.2|refseq:NP_842565.2|ensembl:ENSG00000115306(gene)|ensembl:ENST00000356805(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008091"(spectrin)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0031430"(M band)|go:"GO:0032437"(cuticular plate)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|mint:Q01082|rcsb pdb:1AA2|rcsb pdb:1BKR|rcsb pdb:3EDV|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9703465|reactome:R-HSA-373753|refseq:XP_005264574.1|refseq:XP_006712150.1|refseq:XP_016860268.1|refseq:XP_016860269.1|refseq:XP_016860270.1|dip:DIP-33182N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:rQJxsoEirg87umLjsEwHcQ0/blQ9606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:Q9BTM1 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-4398590|uniprotkb:Q9NV63|ensembl:ENSP00000373730|ensembl:ENSP00000438553 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:h2aj_human(display_long)|uniprotkb:H2AJ(gene name)|psi-mi:H2AJ(display_short)|uniprotkb:H2AFJ(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV refseq:NP_808760.1|ensembl:ENSG00000246705(gene)|ensembl:ENST00000389078(transcript)|ensembl:ENST00000544848(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:4EDU|rcsb pdb:6K60|rcsb pdb:6KVD|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-8939236 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:g6br63FeM17yJRfQI3GnmoM0vbc9606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:O14654 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-356594|ensembl:ENSP00000505547 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:P07437 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:Q9HCC0 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-2211296|uniprotkb:A6NIY9|uniprotkb:Q96C27|uniprotkb:Q9Y4L7|ensembl:ENSP00000343657 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:mccb_human(display_long)|uniprotkb:MCCC2(gene name)|psi-mi:MCCC2(display_short)|uniprotkb:MCCB(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta"(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV refseq:NP_071415.1|refseq:XP_005248624.1|ensembl:ENSG00000131844(gene)|ensembl:ENST00000340941(transcript)|go:"GO:0002169"(3-methylcrotonyl-CoA carboxylase complex, mitochondrial)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR029045|interpro:IPR034733|mint:Q9HCC0|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70895 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:5NkqDKqdX1wHsbqXW7v5+/Gld109606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:Q00610 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-354967|intact:EBI-28974011|ensembl:ENSP00000269122|uniprotkb:Q6N0A0|uniprotkb:Q86TF2|uniprotkb:D3DU00 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:clh1_human(display_long)|uniprotkb:Clathrin heavy chain on chromosome 17(gene name synonym)|uniprotkb:CLTC(gene name)|psi-mi:CLTC(display_short)|uniprotkb:CLH17(gene name synonym)|uniprotkb:KIAA0034(gene name synonym)|uniprotkb:CLTCL2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV ensembl:ENSG00000141367(gene)|ensembl:ENST00000269122(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_004850.1|ensembl:ENSP00000269122|ensembl:ENST00000393043|ensembl:ENSP00000376763|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:Q00610|rcsb pdb:2XZG|rcsb pdb:4G55|rcsb pdb:6E4L|rcsb pdb:6QNN|rcsb pdb:6QNP|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9013420|reactome:R-HSA-9013424 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:oGsLXL5J5MHO+ronpDIG9hJ11sU9606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:O15020 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-308449|uniprotkb:O14872|uniprotkb:O14873|ensembl:ENSP00000311489|ensembl:ENSP00000432568|ensembl:ENSP00000480692|ensembl:ENSP00000508362 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:sptn2_human(display_long)|uniprotkb:SPTBN2(gene name)|psi-mi:SPTBN2(display_short)|uniprotkb:KIAA0302(gene name synonym)|uniprotkb:Beta-III spectrin(gene name synonym)|uniprotkb:SCA5(gene name synonym)|uniprotkb:Spinocerebellar ataxia 5 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV ensembl:ENSG00000173898(gene)|ensembl:ENST00000309996(transcript)|ensembl:ENST00000533211(transcript)|ensembl:ENST00000611817(transcript)|ensembl:ENST00000647510(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0007416"(synapse assembly)|go:"GO:0008091"(spectrin)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0021692"(cerebellar Purkinje cell layer morphogenesis)|go:"GO:0030534"(adult behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045296"(cadherin binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098918"(structural constituent of synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:0099189"(postsynaptic spectrin-associated cytoskeleton)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|mint:O15020|rcsb pdb:1WJM|rcsb pdb:1WYQ|rcsb pdb:6ANU|reactome:R-HSA-2132295|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|refseq:XP_005274249.1|refseq:XP_005274250.1|refseq:XP_006718734.1|refseq:XP_016873663.1|refseq:XP_016873664.1|refseq:XP_016873665.1|refseq:XP_016873666.1|refseq:XP_016873667.1|dip:DIP-47270N|refseq:NP_008877.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:Wfzccja70pnee8sDDc0TCmO6g0I9606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:Q5EBL4 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-2797110|uniprotkb:Q66K36|uniprotkb:Q8N1M0|ensembl:ENSP00000366070 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:ripl1_human(display_long)|uniprotkb:Rab-interacting lysosomal-like protein 1(gene name synonym)|uniprotkb:RILPL1(gene name)|psi-mi:RILPL1(display_short)|uniprotkb:RLP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV refseq:NP_001306172.1|refseq:NP_001306173.1|refseq:NP_001306231.1|refseq:NP_847884.2|ensembl:ENSG00000188026(gene)|ensembl:ENST00000376874(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0060271"(cilium assembly)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1903445"(protein transport from ciliary membrane to plasma membrane)|interpro:IPR019143|interpro:IPR021563|interpro:IPR034743|interpro:IPR034744 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:svCxG6aZws8OxMJdln0pj3rmqps9606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:O00571 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:Q16777 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-5325566|ensembl:ENSP00000332194|uniprotkb:Q6DRA7|uniprotkb:Q8IUE5 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:h2a2c_human(display_long)|uniprotkb:H2AC20(gene name)|psi-mi:H2AC20(display_short)|uniprotkb:H2A-clustered histone 20(gene name synonym)|uniprotkb:H2AFQ(gene name synonym)|uniprotkb:HIST2H2AC(gene name synonym)|uniprotkb:Histone H2A-GL101(gene name synonym)|uniprotkb:Histone H2A/q(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-5689603|ensembl:ENSG00000184260(gene)|ensembl:ENST00000331380(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q16777|rcsb pdb:6Y5E|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|refseq:NP_003508.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:Wejrpp9wK3GvA4ahJDVyEH+cwlQ9606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:Q53SF7 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-2835780|uniprotkb:A6NMZ3|uniprotkb:Q7Z3I6|uniprotkb:Q6IQ33|uniprotkb:Q9Y2I3|uniprotkb:Q9BRH4|uniprotkb:Q9UG88|ensembl:ENSP00000364607|ensembl:ENSP00000498242 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:cobl1_human(display_long)|uniprotkb:COBLL1(gene name)|psi-mi:COBLL1(display_short)|uniprotkb:KIAA0977(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV refseq:NP_055715.3|refseq:NP_001265387.1|refseq:NP_001265389.1|refseq:NP_001265390.1|ensembl:ENSG00000082438(gene)|ensembl:ENST00000375458(transcript)|ensembl:ENST00000652658(transcript)|go:"GO:0003785"(actin monomer binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR019025|interpro:IPR039895|rcsb pdb:2DAJ - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:L7pIsPU2e9KYMTn0alEaL0+5sV09606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:Q9BYP7 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-1182602|uniprotkb:Q5JRC1|uniprotkb:B1AKG2|uniprotkb:Q6JP76|uniprotkb:Q8TCX6|uniprotkb:Q9HCK6|ensembl:ENSP00000346667|ensembl:ENSP00000364301 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:wnk3_human(display_long)|uniprotkb:Protein kinase with no lysine 3(gene name synonym)|uniprotkb:Protein kinase lysine-deficient 3(gene name synonym)|uniprotkb:WNK3(gene name)|psi-mi:WNK3(display_short)|uniprotkb:KIAA1566(gene name synonym)|uniprotkb:PRKWNK3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV refseq:XP_016885230.1|refseq:XP_016885231.1|refseq:XP_016885232.1|refseq:XP_016885233.1|refseq:NP_001002838.1|refseq:NP_065973.2|refseq:XP_011529104.1|ensembl:ENSG00000196632(gene)|ensembl:ENST00000354646(transcript)|ensembl:ENST00000375159(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0007231"(osmosensory signaling pathway)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0032414"(positive regulation of ion transmembrane transporter activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050801"(ion homeostasis)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1904062"(regulation of cation transmembrane transport)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR024678|rcsb pdb:5NKP|rcsb pdb:5O1V|rcsb pdb:5O21|rcsb pdb:5O23|rcsb pdb:5O26|rcsb pdb:5O2B|rcsb pdb:5O2C|reactome:R-HSA-2672351|refseq:XP_016885234.1|refseq:XP_006724656.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:jQ+mq1s+bxAtxjNPqG77sJq8KF89606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:P05166 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-1371908|uniprotkb:Q16813|uniprotkb:Q96CX0|uniprotkb:B7Z2Z4|ensembl:ENSP00000251654 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:pccb_human(display_long)|uniprotkb:PCCB(gene name)|psi-mi:PCCB(display_short)|uniprotkb:"Propanoyl-CoA:carbon dioxide ligase subunit beta"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV refseq:NP_000523.2|refseq:NP_001171485.1|dip:DIP-38244N|mint:P05166|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-71032|interpro:IPR034733|ensembl:ENSG00000114054(gene)|ensembl:ENST00000251654(transcript)|go:"GO:0004658"(propionyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0019626"(short-chain fatty acid catabolic process)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR029045 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:QyhO7MHvNRxNMg7ohwi1xS+VxQE9606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:Q9H4A3 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-457907|uniprotkb:O15052|uniprotkb:P54963|uniprotkb:Q86WL5|uniprotkb:Q8N673|uniprotkb:Q9P1S9|uniprotkb:Q4VBX9|intact:EBI-948424|uniprotkb:A1L4B0|uniprotkb:Q6IFS5|uniprotkb:C5HTZ5|uniprotkb:C5HTZ6|uniprotkb:C5HTZ7|uniprotkb:H6WZW3|uniprotkb:Q96CZ6|ensembl:ENSP00000313059 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:wnk1_human(display_long)|uniprotkb:WNK1(gene name)|psi-mi:WNK1(display_short)|uniprotkb:KDP(gene name synonym)|uniprotkb:KIAA0344(gene name synonym)|uniprotkb:PRKWNK1(gene name synonym)|uniprotkb:Protein kinase with no lysine 1(gene name synonym)|uniprotkb:Protein kinase lysine-deficient 1(gene name synonym)|uniprotkb:Erythrocyte 65 kDa protein(gene name synonym)|uniprotkb:Kinase deficient protein(gene name synonym)|uniprotkb:HSN2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV ensembl:ENSP00000313059|ensembl:ENST00000340908|ensembl:ENSP00000341292|ensembl:ENST00000530271|ensembl:ENSP00000433548|ensembl:ENST00000537687|ensembl:ENSP00000444465|ensembl:ENST00000675631|ensembl:ENSP00000502415|refseq:NP_001171914.1|refseq:NP_055638.2|refseq:NP_061852.3|refseq:NP_998820.3|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1904062"(regulation of cation transmembrane transport)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR024678|mint:Q9H4A3|rcsb pdb:4PWN|rcsb pdb:5TF9|rcsb pdb:5WDY|rcsb pdb:5WE8|rcsb pdb:6FBK|reactome:R-HSA-2672351|go:"GO:0097022"(lymphocyte migration into lymph node)|ensembl:ENSG00000060237(gene)|ensembl:ENST00000315939(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006811"(ion transport)|go:"GO:0007165"(signal transduction)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0033633"(negative regulation of cell-cell adhesion mediated by integrin)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038116"("chemokine (C-C motif) ligand 21 signaling pathway")|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048666"(neuron development)|go:"GO:0050794"(regulation of cellular process)|go:"GO:0050801"(ion homeostasis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0003084"(positive regulation of systemic arterial blood pressure)|refseq:XP_016875326.1|refseq:XP_016875327.1|dip:DIP-32648N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:Jt4cvhSumyRRIZDmWgj4GsG7wjQ9606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:P11021 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:P20671 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-4407441|uniprotkb:A0PK91|uniprotkb:P57754|uniprotkb:Q6FGY6|ensembl:ENSP00000341094 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:h2a1d_human(display_long)|uniprotkb:H2AC7(gene name)|psi-mi:H2AC7(display_short)|uniprotkb:H2AFG(gene name synonym)|uniprotkb:HIST1H2AD(gene name synonym)|uniprotkb:Histone H2A.3(gene name synonym)|uniprotkb:Histone H2A/g(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV refseq:NP_066409.1|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000196866(gene)|ensembl:ENST00000341023(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:5GT3|rcsb pdb:6KBB|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:Geraq+dGw3pvAAhgzzXQnYxDOOw9606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:Q9Y3S1 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-948521|uniprotkb:Q8IY36|uniprotkb:Q9C0A3|uniprotkb:Q9H3P4|uniprotkb:Q5VWF1|uniprotkb:Q5VWF2|ensembl:ENSP00000297954 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:wnk2_human(display_long)|uniprotkb:Protein kinase with no lysine 2(gene name synonym)|uniprotkb:Protein kinase lysine-deficient 2(gene name synonym)|uniprotkb:Serologically defined colon cancer antigen 43(gene name synonym)|uniprotkb:Antigen NY-CO-43(gene name synonym)|uniprotkb:WNK2(gene name)|psi-mi:WNK2(display_short)|uniprotkb:KIAA1760(gene name synonym)|uniprotkb:PRKWNK2(gene name synonym)|uniprotkb:P/OKcl.13(orf name)|uniprotkb:SDCCAG43(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV ensembl:ENSP00000297954|refseq:NP_001269323.1|refseq:XP_005252197.1|ensembl:ENSG00000165238(gene)|ensembl:ENST00000297954(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050801"(ion homeostasis)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR024678|rcsb pdb:6ELM|rcsb pdb:6FBK|reactome:R-HSA-2672351 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:+Q63ncfKZnhhD2F9FQY1iX3ObCc9606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:Q99878 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-6147676|uniprotkb:Q5JXQ5|uniprotkb:A2RUU6|ensembl:ENSP00000328484 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:h2a1j_human(display_long)|uniprotkb:H2AC14(gene name)|psi-mi:H2AC14(display_short)|uniprotkb:H2AFE(gene name synonym)|uniprotkb:HIST1H2AJ(gene name synonym)|uniprotkb:Histone H2A/e(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV refseq:NP_066544.1|ensembl:ENSG00000276368(gene)|ensembl:ENST00000333151(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:tS29VG3PpglHaYbu0w5z7pGvYyI9606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:Q13085 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-717681|intact:EBI-3962262|uniprotkb:B2ZZ90|uniprotkb:Q6KEV6|uniprotkb:Q6XDA8|uniprotkb:Q7Z2G8|uniprotkb:Q7Z561|uniprotkb:Q7Z563|uniprotkb:Q7Z564|uniprotkb:Q86WB2|uniprotkb:Q86WB3|uniprotkb:B2RP68|ensembl:ENSP00000478547|ensembl:ENSP00000483674 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:acaca_human(display_long)|uniprotkb:ACACA(gene name)|psi-mi:ACACA(display_short)|uniprotkb:ACAC(gene name synonym)|uniprotkb:ACC1(gene name synonym)|uniprotkb:ACCA(gene name synonym)|uniprotkb:Acetyl-Coenzyme A carboxylase alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV refseq:NP_942131.1|refseq:NP_942133.1|refseq:NP_942134.1|refseq:NP_942135.1|refseq:NP_942136.1|refseq:XP_016880044.1|refseq:XP_011523005.1|ensembl:ENSG00000275176(gene)|ensembl:ENSG00000278540(gene)|ensembl:ENST00000613687(transcript)|ensembl:ENST00000614428(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003989"(acetyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019538"(protein metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:2001295"(malonyl-CoA biosynthetic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013537(Acetyl-CoA carboxylase, central region)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR029045|interpro:IPR034733|mint:Q13085|rcsb pdb:2YL2|rcsb pdb:3COJ|rcsb pdb:4ASI|rcsb pdb:6G2D|rcsb pdb:6G2H|rcsb pdb:6G2I|reactome:R-HSA-163765|reactome:R-HSA-196780|reactome:R-HSA-200425|reactome:R-HSA-2426168|reactome:R-HSA-3371599|reactome:R-HSA-75105|dip:DIP-36122N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:P9d0QlkoP1zrBdF1WOrK68ueGng9606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:Q08AE8 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-1055655|uniprotkb:Q1RMD4|uniprotkb:Q9NQ71|uniprotkb:Q9ULT4|uniprotkb:A8K2B5|uniprotkb:Q8NDP1|uniprotkb:J3KQ50|uniprotkb:J3KQR5|ensembl:ENSP00000387266 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:spir1_human(display_long)|uniprotkb:SPIR1(gene name synonym)|uniprotkb:SPIRE1(gene name)|psi-mi:SPIRE1(display_short)|uniprotkb:KIAA1135(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV refseq:NP_001122098.1|refseq:NP_001122099.1|refseq:NP_064533.3|ensembl:ENST00000409402(transcript)|ensembl:ENSG00000134278(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0040038"(polar body extrusion after meiotic divisions)|go:"GO:0045010"(actin nucleation)|go:"GO:0046907"(intracellular transport)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0051639"(actin filament network formation)|go:"GO:0070649"(formin-nucleated actin cable assembly)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011019(KIND)|interpro:IPR029901|interpro:IPR029905|mint:Q08AE8|rcsb pdb:2YLE|rcsb pdb:2YLF|rcsb pdb:3R7G|rcsb pdb:3RBW|go:"GO:0003779"(actin binding)|dip:DIP-42378N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:y/XOE8pHx7hdvdupDmeINEq7L+M9606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:P62805 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:P04908 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:4Qno1mMYZB6FdNoojrzulWLVq849606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:Q7L7L0 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-5325551|ensembl:ENSP00000355656|ensembl:ENSP00000493926|uniprotkb:B2R4S4 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:h2a3_human(display_long)|uniprotkb:H2AW(gene name)|psi-mi:H2AW(display_short)|uniprotkb:HIST3H2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV ensembl:ENSG00000181218(gene)|ensembl:ENSG00000284841(gene)|ensembl:ENST00000366695(transcript)|refseq:NP_254280.1|ensembl:ENST00000645741(transcript)|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-5689603|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q7L7L0|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000786"(nucleosome)|dip:DIP-48936N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:t0RdR1SmUtmwRjtCS3uTyLGqSUI9606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P68466 uniprotkb:Q93077 intact:EBI-6152154|uniprotkb:P18382 intact:EBI-725259|uniprotkb:O00775|uniprotkb:O00776|uniprotkb:O00777|uniprotkb:O00778|uniprotkb:Q540R1|uniprotkb:B2R4F7|ensembl:ENSP00000321389|ensembl:ENSP00000367022|ensembl:ENSP00000473534 psi-mi:k7_vaccw(display_long)|uniprotkb:K7R(orf name)|uniprotkb:VACWR039(locus name) psi-mi:h2a1c_human(display_long)|uniprotkb:H2AC6(gene name)|psi-mi:H2AC6(display_short)|uniprotkb:H2A-clustered histone 6(gene name synonym)|uniprotkb:H2AFL(gene name synonym)|uniprotkb:HIST1H2AC(gene name synonym)|uniprotkb:Histone H2A/l(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6158939|imex:IM-17331-58 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_232921.1|dip:DIP-48288N|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|interpro:IPR009174(Uncharacterised conserved protein VAC-K7R)|interpro:IPR022819|interpro:IPR043018|rcsb pdb:2K36|rcsb pdb:3JRV refseq:NP_003503.1|ensembl:ENSG00000180573(gene)|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENST00000314088(transcript)|ensembl:ENST00000377791(transcript)|ensembl:ENST00000602637(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|rcsb pdb:6C0W|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:7A08|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|interpro:IPR032458 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/09/20 rogid:qqta4Twob1ullrnaJdJpyUZ83Fc10254 rogid:m00IdooZksbNGKHSsaVvGFVpcko9606 intact-crc:F1FE017EF9201B4F|rigid:SeomuMlBEai9hDqY+RwdznOKpdM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:P50990 intact:EBI-6152249 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q96S55 intact:EBI-6152249 intact:EBI-2513471|ensembl:ENSP00000370150|ensembl:ENSP00000477551|uniprotkb:Q9NRJ6|uniprotkb:Q5W0E2|uniprotkb:Q53EP6|uniprotkb:Q8WV26|uniprotkb:Q5W0E4|uniprotkb:Q59ET8|uniprotkb:Q9H681|uniprotkb:B2RDB0 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:wrip1_human(display_long)|uniprotkb:WRNIP1(gene name)|psi-mi:WRNIP1(display_short)|uniprotkb:WHIP(gene name synonym)|uniprotkb:Werner helicase-interacting protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 ensembl:ENSG00000124535(gene)|ensembl:ENST00000380773(transcript)|ensembl:ENST00000618555(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR021886|interpro:IPR027417|interpro:IPR032423|interpro:IPR040539|mint:Q96S55|rcsb pdb:3VHS|rcsb pdb:3VHT|go:"GO:0017116"(single-stranded DNA helicase activity)|refseq:NP_064520.2|refseq:NP_569079.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:Q8qVSqItgTO7sbWGAQ3XAoFFUr89606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q53EZ4 intact:EBI-6152249 intact:EBI-747776|uniprotkb:Q32WF5|uniprotkb:Q3MV20|uniprotkb:Q5VY28|uniprotkb:Q6N034|ensembl:ENSP00000360540|uniprotkb:Q96H32|uniprotkb:Q9NVS7|uniprotkb:B2RDG8|intact:EBI-10173536|uniprotkb:D3DR37|intact:EBI-28973801 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:cep55_human(display_long)|uniprotkb:Up-regulated in colon cancer 6(gene name synonym)|uniprotkb:CEP55(gene name)|psi-mi:CEP55(display_short)|uniprotkb:URCC6(gene name synonym)|uniprotkb:C10orf3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_001120654.1|refseq:NP_060601.3|ensembl:ENSG00000138180(gene)|ensembl:ENST00000371485(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0061952"(midbody abscission)|go:"GO:0090543"(Flemming body)|go:"GO:1904888"(cranial skeletal system development)|interpro:IPR022008|interpro:IPR038926|mint:Q53EZ4|rcsb pdb:3E1R|rcsb pdb:3WUT|rcsb pdb:3WUU|rcsb pdb:3WUV|go:"GO:0005814"(centriole)|ensembl:ENSP00000360540|dip:DIP-44581N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:tuo36vVb8ZgPDR81YjZFNEg559w9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:P17987 intact:EBI-6152249 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:P50991 intact:EBI-6152249 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q05639 intact:EBI-6152249 intact:EBI-354943|ensembl:ENSP00000217182|uniprotkb:P54266|uniprotkb:Q0VGC7|uniprotkb:B5BUF3|uniprotkb:E1P5J1 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:ef1a2_human(display_long)|uniprotkb:EEF1A2(gene name)|psi-mi:EEF1A2(display_short)|uniprotkb:EEF1AL(gene name synonym)|uniprotkb:STN(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-2(gene name synonym)|uniprotkb:Statin-S1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 ensembl:ENSG00000101210(gene)|ensembl:ENST00000217182(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0090218"(positive regulation of lipid kinase activity)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:Q05639|rcsb pdb:3C5J|reactome:R-HSA-156842|refseq:NP_001949.1|dip:DIP-40060N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:vFXfcSRokxKo5RW0tRE1qEK0NKw9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:P34931 intact:EBI-6152249 intact:EBI-354912|uniprotkb:O75634|uniprotkb:Q2HXR3|uniprotkb:Q8NE72|uniprotkb:A6NNB0|uniprotkb:Q96QC9|uniprotkb:Q9UQM1|uniprotkb:B0UXW8|ensembl:ENSP00000364805|ensembl:ENSP00000372881|ensembl:ENSP00000396486|ensembl:ENSP00000408347 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:hs71l_human(display_long)|uniprotkb:HSPA1L(gene name)|psi-mi:HSPA1L(display_short)|uniprotkb:Heat shock 70 kDa protein 1-Hom(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_005518.3|ensembl:ENSG00000204390(gene)|ensembl:ENSG00000206383(gene)|ensembl:ENSG00000234258(gene)|ensembl:ENSG00000236251(gene)|ensembl:ENST00000375654(transcript)|ensembl:ENST00000383390(transcript)|ensembl:ENST00000417601(transcript)|ensembl:ENST00000456772(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0072562"(blood microparticle)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P34931|rcsb pdb:3GDQ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:KS02DcMpD2sxSF36hUjKiSdYi4c9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q92841 intact:EBI-6152249 intact:EBI-746012|uniprotkb:Q69YT1|uniprotkb:Q6ICD6|uniprotkb:H3BLZ8|uniprotkb:B1AHM0|ensembl:ENSP00000385536 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:ddx17_human(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:RNA-dependent helicase p72(gene name synonym)|uniprotkb:DEAD box protein p72(gene name synonym)|uniprotkb:DDX17(gene name)|psi-mi:DDX17(display_short)|uniprotkb:DEAD box protein p82(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_006377.2|ensembl:ENSG00000100201(gene)|ensembl:ENST00000403230(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q92841|rcsb pdb:6UV0|rcsb pdb:6UV1|rcsb pdb:6UV2|rcsb pdb:6UV3|rcsb pdb:6UV4|reactome:R-HSA-3899300|dip:DIP-29843N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:3UhUuhRSZg/zlM7UPDKYCqNmUho9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:P48643 intact:EBI-6152249 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q14653 intact:EBI-6152249 intact:EBI-2650369|uniprotkb:Q5FBY1|uniprotkb:Q5FBY2|uniprotkb:Q7Z5G6|uniprotkb:A8K7L2|uniprotkb:B2RAZ3|ensembl:ENSP00000310127|ensembl:ENSP00000366344|ensembl:ENSP00000469113|uniprotkb:Q5FBY4 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:irf3_human(display_long)|uniprotkb:IRF3(gene name)|psi-mi:IRF3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_001562.1|refseq:NP_001184053.1|ensembl:ENSG00000126456(gene)|ensembl:ENST00000309877(transcript)|ensembl:ENST00000377139(transcript)|ensembl:ENST00000597198(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0035666"(TRIF-dependent toll-like receptor signaling pathway)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071888"(macrophage apoptotic process)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0098586"(cellular response to virus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001346(Interferon regulatory factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR017855(SMAD domain-like)|interpro:IPR019471|interpro:IPR019817|interpro:IPR036388|interpro:IPR036390|mint:Q14653|rcsb pdb:1J2F|rcsb pdb:1QWT|rcsb pdb:1T2K|rcsb pdb:1ZOQ|rcsb pdb:2O61|rcsb pdb:2O6G|rcsb pdb:2PI0|rcsb pdb:3A77|rcsb pdb:3QU6|rcsb pdb:5JEJ|rcsb pdb:5JEK|rcsb pdb:5JEL|rcsb pdb:5JEM|rcsb pdb:5JEO|rcsb pdb:5JER|rcsb pdb:6SIV|rcsb pdb:6SJA|rcsb pdb:7JFL|reactome:R-HSA-1169408|reactome:R-HSA-1606341|reactome:R-HSA-168928|reactome:R-HSA-3134975|reactome:R-HSA-3270619|reactome:R-HSA-877300|reactome:R-HSA-3134973|reactome:R-HSA-9013973|reactome:R-HSA-909733|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-936440|reactome:R-HSA-936964|refseq:NP_001184051.1|refseq:NP_001184052.1|refseq:NP_001184054.1|refseq:NP_001184055.1|refseq:NP_001184056.1|refseq:NP_001184057.1|refseq:XP_006723260.1|refseq:XP_006723261.1|refseq:XP_016882255.1|refseq:XP_016882256.1|dip:DIP-41448N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:hQC59YXQ7BOkhZzKbxYHcu1YWFA9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q99536 intact:EBI-6152249 intact:EBI-2514883|ensembl:ENSP00000347872|uniprotkb:Q5BKZ7|uniprotkb:A8K345|uniprotkb:Q13035|uniprotkb:Q9BUT8|uniprotkb:Q96A39|uniprotkb:B0AZP7|uniprotkb:B4DPX4 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:vat1_human(display_long)|uniprotkb:VAT1(gene name)|psi-mi:VAT1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 rcsb pdb:6K9Y|rcsb pdb:6LHR|rcsb pdb:6LII|reactome:R-HSA-6798695|ensembl:ENSG00000108828(gene)|ensembl:ENST00000355653(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002364(Quinone oxidoreductase/zeta-crystallin, conserved site)|interpro:IPR011032(GroES-like)|interpro:IPR013154(Alcohol dehydrogenase GroES-like)|interpro:IPR020843|interpro:IPR036291|mint:Q99536|refseq:NP_006364.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:CaICWyJ+h3ry4itndQodektQFQo9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q08379 intact:EBI-6152249 intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:O00571 intact:EBI-6152249 intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:P14649 intact:EBI-6152249 intact:EBI-358570|ensembl:ENSP00000446643|ensembl:ENSP00000450385 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:myl6b_human(display_long)|uniprotkb:MYL6B(gene name)|psi-mi:MYL6B(display_short)|uniprotkb:MLC1SA(gene name synonym)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6B(gene name synonym)|uniprotkb:Myosin light chain 1 slow-twitch muscle A isoform(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_001186558.1|refseq:NP_002466.1|ensembl:ENSG00000196465(gene)|ensembl:ENST00000550443(transcript)|ensembl:ENST00000553066(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:1OE9|rcsb pdb:1W7I|rcsb pdb:1W7J|reactome:R-HSA-445355 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:S0/S5hUxfyyve1JDMojIggOSBb89606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:P41091 intact:EBI-6152249 intact:EBI-1054228|uniprotkb:B5BTZ4|intact:EBI-11602611|uniprotkb:A0A024RBY4|uniprotkb:A8K2Y2|uniprotkb:B2R5N2|uniprotkb:Q53HK3|ensembl:ENSP00000253039 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:if2g_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 2 subunit gamma X(gene name synonym)|uniprotkb:EIF2S3(gene name)|psi-mi:EIF2S3(display_short)|uniprotkb:EIF2G(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_001406.1|ensembl:ENSG00000130741(gene)|ensembl:ENST00000253039(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR044127|interpro:IPR044128|rcsb pdb:6FEC|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6YBV|rcsb pdb:6ZMW|rcsb pdb:6ZP4|rcsb pdb:7A09|rcsb pdb:7D43|reactome:R-HSA-156827|reactome:R-HSA-381042|reactome:R-HSA-382556|reactome:R-HSA-72649|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72731|reactome:R-HSA-9633012|reactome:R-HSA-9648895|interpro:IPR027417 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:6uBTiGTvEKMfS0NqkKGIaSR61j89606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q5VIR6 intact:EBI-6152249 intact:EBI-2850511|uniprotkb:Q9BY02|uniprotkb:A8K2S8|uniprotkb:Q9BRR2|uniprotkb:Q9NV25|uniprotkb:Q8WYW3|uniprotkb:B3FH42|ensembl:ENSP00000401435|ensembl:ENSP00000492761|ensembl:ENSP00000505997 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:vps53_human(display_long)|uniprotkb:PP13624(orf name)|uniprotkb:VPS53(gene name)|psi-mi:VPS53(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_001121631.1|refseq:NP_060759.2|dip:DIP-59352N|ensembl:ENSG00000141252(gene)|ensembl:ENSG00000283883(gene)|ensembl:ENST00000437048(transcript)|ensembl:ENST00000639801(transcript)|ensembl:ENST00000680465(transcript)|go:"GO:0000938"(GARP complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007041"(lysosomal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:1990745"(EARP complex)|interpro:IPR007234(Vps53-like, N-terminal)|interpro:IPR038260|interpro:IPR039766|reactome:R-HSA-6811440 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:gnrMqPquSOGNPQYESYuA7ztMI0Y9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q92734 intact:EBI-6152249 intact:EBI-357061|uniprotkb:Q15656|intact:EBI-357314|uniprotkb:Q969I2|uniprotkb:D3DN49|uniprotkb:K0J5S8|uniprotkb:K0J6K2|intact:EBI-28969365|ensembl:ENSP00000240851|ensembl:ENSP00000419960|ensembl:ENSP00000420797|ensembl:ENSP00000501815|ensembl:ENSP00000502071|ensembl:ENSP00000502450|ensembl:ENSP00000502592|ensembl:ENSP00000502734|uniprotkb:G5E9V1 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:tfg_human(display_long)|uniprotkb:TFG(gene name)|psi-mi:TFG(display_short)|uniprotkb:TRK-fused gene protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_001007566.1|refseq:NP_001182407.1|refseq:NP_001182408.1|refseq:NP_006061.2|ensembl:ENSP00000240851|ensembl:ENST00000463568|ensembl:ENSP00000419504|ensembl:ENST00000476228|ensembl:ENSP00000417952|ensembl:ENSP00000420797|ensembl:ENSP00000419960|ensembl:ENST00000615993|ensembl:ENSP00000479269|ensembl:ENST00000620299|ensembl:ENSP00000479981|ensembl:ENSP00000502734|ensembl:ENST00000674645|ensembl:ENSP00000501892|ensembl:ENST00000674758|ensembl:ENSP00000502502|ensembl:ENST00000675047|ensembl:ENSP00000502497|ensembl:ENSP00000502592|ensembl:ENST00000675420|ensembl:ENSP00000502516|ensembl:ENSP00000502450|ensembl:ENST00000675543|ensembl:ENSP00000501815|ensembl:ENST00000675586|ensembl:ENSP00000502329|ensembl:ENST00000676111|ensembl:ENSP00000502139|ensembl:ENST00000676308|ensembl:ENSP00000502697|ensembl:ENSP00000502071|ensembl:ENST00000676431|ensembl:ENSP00000502698|ensembl:ENSP00000502229|refseq:XP_006713535.1|refseq:XP_006713536.1|ensembl:ENSG00000114354(gene)|ensembl:ENST00000240851(transcript)|ensembl:ENST00000487505(transcript)|ensembl:ENST00000490574(transcript)|ensembl:ENST00000674615(transcript)|ensembl:ENST00000675243(transcript)|ensembl:ENST00000675499(transcript)|ensembl:ENST00000675553(transcript)|ensembl:ENST00000676395(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR033512|interpro:IPR034857|mint:Q92734|reactome:R-HSA-204005|refseq:XP_011510636.1|refseq:XP_005247123.1|refseq:XP_016861016.1|refseq:XP_016861017.1|refseq:XP_016861018.1|refseq:XP_016861019.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:y7aghh0X3Ewgpzcx5h5nB+X2dII9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:O15523 intact:EBI-6152249 intact:EBI-2462220|uniprotkb:Q8IYV7|uniprotkb:B4DK29|uniprotkb:B4DXX7|ensembl:ENSP00000336725|ensembl:ENSP00000353284 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:ddx3y_human(display_long)|uniprotkb:DDX3Y(gene name)|psi-mi:DDX3Y(display_short)|uniprotkb:DBY(gene name synonym)|uniprotkb:DEAD box protein 3, Y-chromosomal(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_001116137.1|refseq:NP_004651.2|refseq:NP_001289481.1|ensembl:ENSG00000067048(gene)|ensembl:ENST00000336079(transcript)|ensembl:ENST00000360160(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007276"(gamete generation)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O15523 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:dYhBr9Igq5eMq9U8g+c30nfdaKo9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:P49368 intact:EBI-6152249 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q92945 intact:EBI-6152249 intact:EBI-1049099|uniprotkb:O00301|uniprotkb:Q59EZ9|uniprotkb:Q5U4P6|uniprotkb:Q9UNT5|uniprotkb:Q9UQH5|intact:EBI-5455671|ensembl:ENSP00000381216 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:fubp2_human(display_long)|uniprotkb:KH type-splicing regulatory protein(gene name synonym)|uniprotkb:p75(gene name synonym)|uniprotkb:KHSRP(gene name)|psi-mi:KHSRP(display_short)|uniprotkb:FUBP2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_003676.2|ensembl:ENSG00000088247(gene)|ensembl:ENST00000398148(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0010989"(negative regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0051028"(mRNA transport)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071345"(cellular response to cytokine stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR015096(Region of unknown function DUF1897)|interpro:IPR036612|mint:Q92945|rcsb pdb:2HH2|rcsb pdb:2HH3|rcsb pdb:2JVZ|rcsb pdb:2OPU|rcsb pdb:2OPV|rcsb pdb:4B8T|reactome:R-HSA-380994|reactome:R-HSA-450604|dip:DIP-48484N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:hlybJllTqSgPgtwwz3kc12zDYh49606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:O00746 intact:EBI-6152249 intact:EBI-744871|uniprotkb:Q5U0M9|ensembl:ENSP00000219479|uniprotkb:A2IDD0 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:ndkm_human(display_long)|uniprotkb:nm23-H4(gene name synonym)|uniprotkb:Nucleoside diphosphate kinase D(gene name synonym)|uniprotkb:NME4(gene name)|psi-mi:NME4(display_short)|uniprotkb:NM23D(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_001273362.1|refseq:NP_001273364.1|refseq:NP_001273365.1|refseq:NP_001273367.1|refseq:NP_001273368.1|refseq:NP_001273369.1|refseq:NP_005000.1|ensembl:ENSG00000103202(gene)|ensembl:ENST00000219479(transcript)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006869"(lipid transport)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:1901612"(cardiolipin binding)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850|mint:O00746|rcsb pdb:1EHW|reactome:R-HSA-499943 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:ybA9I8oT+oz1iuGLHT7WR1SAaKY9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q71U36 intact:EBI-6152249 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q9BQE3 intact:EBI-6152249 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q2VIR3 intact:EBI-6152249 intact:EBI-6152253|uniprotkb:F8W810|uniprotkb:Q5I0X0|uniprotkb:Q6KF84|ensembl:ENSP00000445077 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:if2gl_human(display_long)|uniprotkb:EIF2S3B(gene name)|psi-mi:EIF2S3B(display_short)|uniprotkb:Eukaryotic translation initiation factor 2 subunit gamma A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 ensembl:ENSG00000180574(gene)|ensembl:ENST00000538173(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0045903"(positive regulation of translational fidelity)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015256(Initiation factor eIF2 gamma, C terminal)|interpro:IPR027417|interpro:IPR044127|interpro:IPR044128 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:PWCg1+Txl6XGdC4iHan7A9SGDwg9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q9Y224 intact:EBI-6152249 intact:EBI-1104547|ensembl:ENSP00000261700 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:rtraf_human(display_long)|uniprotkb:RTRAF(gene name)|psi-mi:RTRAF(display_short)|uniprotkb:C14orf166(gene name synonym)|uniprotkb:CLE7 homolog(gene name synonym)|uniprotkb:CGI-99(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_057123.1|ensembl:ENSG00000087302(gene)|ensembl:ENST00000261700(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050658"(RNA transport)|go:"GO:0072669"(tRNA-splicing ligase complex)|go:"GO:0072686"(mitotic spindle)|interpro:IPR019265|mint:Q9Y224|reactome:R-HSA-6784531 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:KRP0BO8XmEAtBag6wdctMHgVaEI9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q7L273 intact:EBI-6152249 intact:EBI-4397613|uniprotkb:Q6NUM8|uniprotkb:Q9NXV4|ensembl:ENSP00000221200 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:kctd9_human(display_long)|uniprotkb:KCTD9(gene name)|psi-mi:KCTD9(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_060104.2|ensembl:ENSG00000104756(gene)|ensembl:ENST00000221200(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001646(Pentapeptide repeat)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR021789|interpro:IPR036572|mint:Q7L273|rcsb pdb:5BXH - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:coM0kMYFDztNUR3W7/LsLlFMNXg9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q8N1B4 intact:EBI-6152249 intact:EBI-2799833|ensembl:ENSP00000372697|ensembl:ENSP00000390831|ensembl:ENSP00000391197|ensembl:ENSP00000404016|ensembl:ENSP00000406988|ensembl:ENSP00000409952|uniprotkb:B4DNI9|uniprotkb:Q9NPT5|uniprotkb:Q8IUN6|uniprotkb:Q5JPA0|uniprotkb:Q53GR4|uniprotkb:Q5SQW1|uniprotkb:B0UZZ4|uniprotkb:A2BF38 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:vps52_human(display_long)|uniprotkb:SACM2L(gene name synonym)|uniprotkb:SAC2 suppressor of actin mutations 2-like protein(gene name synonym)|uniprotkb:VPS52(gene name)|psi-mi:VPS52(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 ensembl:ENSG00000223501(gene)|ensembl:ENSG00000224455(gene)|ensembl:ENSG00000225590(gene)|ensembl:ENSG00000228425(gene)|ensembl:ENSG00000236014(gene)|ensembl:ENST00000383210(transcript)|ensembl:ENST00000428608(transcript)|ensembl:ENST00000441058(transcript)|ensembl:ENST00000443860(transcript)|ensembl:ENST00000445902(transcript)|ensembl:ENST00000448042(transcript)|go:"GO:0000938"(GARP complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007041"(lysosomal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010668"(ectodermal cell differentiation)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048611"(embryonic ectodermal digestive tract development)|go:"GO:0055037"(recycling endosome)|go:"GO:1990745"(EARP complex)|interpro:IPR007258(Vps52/Sac2)|reactome:R-HSA-6811440|ensembl:ENSG00000206286(gene)|refseq:NP_001276104.1|refseq:NP_072047.4|refseq:NP_001276105.1|refseq:XP_016866667.1|dip:DIP-57843N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:fMptnw5eMhxv+AzDK/+mSKrL7uY9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q9Y4K3 intact:EBI-6152249 intact:EBI-359276|uniprotkb:Q8NEH5|uniprotkb:A6NKI7|uniprotkb:A8KAB3|ensembl:ENSP00000337853|ensembl:ENSP00000433623|uniprotkb:D3DR16 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:traf6_human(display_long)|uniprotkb:TRAF6(gene name)|psi-mi:TRAF6(display_short)|uniprotkb:RNF85(gene name synonym)|uniprotkb:Interleukin-1 signal transducer(gene name synonym)|uniprotkb:RING finger protein 85(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRAF6(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_004611.1|refseq:NP_665802.1|ensembl:ENSG00000175104(gene)|ensembl:ENST00000348124(transcript)|ensembl:ENST00000526995(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001503"(ossification)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001843"(neural tube closure)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002637"(regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007254"(JNK cascade)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031666"(positive regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045453"(bone resorption)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048468"(cell development)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027139|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|interpro:IPR037309|interpro:IPR041310|interpro:IPR043211|mint:Q9Y4K3|rcsb pdb:1LB4|rcsb pdb:1LB5|go:"GO:0070534"(protein K63-linked ubiquitination)|rcsb pdb:1LB6|rcsb pdb:2ECI|rcsb pdb:2JMD|rcsb pdb:3HCS|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:4Z8M|rcsb pdb:5ZUJ|rcsb pdb:6A33|go:"GO:0070555"(response to interleukin-1)|rcsb pdb:7L3L|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-205043|go:"GO:0071222"(cellular response to lipopolysaccharide)|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2871837|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097400"(interleukin-17-mediated signaling pathway)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR001293(Zinc finger, TRAF-type)|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975163|reactome:R-HSA-975871|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|dip:DIP-27515N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:m0TTXwlrtXnnjXWbg0MsEULlq0I9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:P49770 intact:EBI-6152249 intact:EBI-718773|uniprotkb:O43201|ensembl:ENSP00000266126 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:ei2bb_human(display_long)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit beta(gene name synonym)|uniprotkb:S20I15(gene name synonym)|uniprotkb:S20III15(gene name synonym)|uniprotkb:EIF2B2(gene name)|psi-mi:EIF2B2(display_short)|uniprotkb:EIF2BB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_055054.1|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007417"(central nervous system development)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0042552"(myelination)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042529|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731|ensembl:ENSG00000119718(gene)|ensembl:ENST00000266126(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:CLCdt90SBzvMUBXSQDb6DTy3Yz09606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q9Y6D9 intact:EBI-6152249 intact:EBI-742610|uniprotkb:B3KR41|uniprotkb:Q9UNH0|uniprotkb:Q13312|uniprotkb:Q75MI0|uniprotkb:Q86UM4|ensembl:ENSP00000265854|ensembl:ENSP00000382562|ensembl:ENSP00000385334 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:md1l1_human(display_long)|uniprotkb:Mitotic arrest deficient 1-like protein 1(gene name synonym)|uniprotkb:Mitotic checkpoint MAD1 protein homolog(gene name synonym)|uniprotkb:Tax-binding protein 181(gene name synonym)|uniprotkb:MAD1L1(gene name)|psi-mi:MAD1L1(display_short)|uniprotkb:MAD1(gene name synonym)|uniprotkb:TXBP181(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_001013858.1|refseq:NP_001013859.1|refseq:NP_003541.2|refseq:NP_001291452.1|refseq:NP_001291453.1|ensembl:ENSG00000002822(gene)|ensembl:ENST00000265854(transcript)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|mint:Q9Y6D9|rcsb pdb:1GO4|rcsb pdb:4DZO|rcsb pdb:7B1F|rcsb pdb:7B1H|rcsb pdb:7B1J|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENST00000399654(transcript)|ensembl:ENST00000406869(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048538"(thymus development)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|refseq:XP_005249934.1|dip:DIP-29654N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:9CcqpZlN0IgqC939rIo7vNgOvLQ9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:P35637 intact:EBI-6152249 intact:EBI-400434|uniprotkb:Q9H4A8|ensembl:ENSP00000254108 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:fus_human(display_long)|uniprotkb:FUS(gene name)|psi-mi:FUS(display_short)|uniprotkb:TLS(gene name synonym)|uniprotkb:Oncogene FUS(gene name synonym)|uniprotkb:Oncogene TLS(gene name synonym)|uniprotkb:Translocated in liposarcoma protein(gene name synonym)|uniprotkb:POMp75(gene name synonym)|uniprotkb:75 kDa DNA-pairing protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_001164105.1|refseq:NP_004951.1|ensembl:ENSG00000089280(gene)|ensembl:ENST00000254108(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008380"(RNA splicing)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044327"(dendritic spine head)|go:"GO:0046872"(metal ion binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034459|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:P35637|rcsb pdb:2LA6|rcsb pdb:2LCW|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:5W3N|rcsb pdb:5XRR|rcsb pdb:5XSG|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:6BWZ|rcsb pdb:6BXV|rcsb pdb:6BZP|rcsb pdb:6G99|rcsb pdb:6GBM|rcsb pdb:6KJ1|rcsb pdb:6KJ2|rcsb pdb:6KJ3|rcsb pdb:6KJ4|rcsb pdb:6SNJ|rcsb pdb:6XFM|rcsb pdb:7CYL|reactome:R-HSA-72163|dip:DIP-29857N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:HUP4fGXQyJnm5CFTuwjTpiucZOc9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:P07437 intact:EBI-6152249 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q9NR50 intact:EBI-6152249 intact:EBI-702257|uniprotkb:Q5QP89|uniprotkb:Q5QP90|uniprotkb:Q8NDB5|uniprotkb:Q8WV57|uniprotkb:Q9H850|uniprotkb:B2RBH8|uniprotkb:D3DPZ2|ensembl:ENSP00000353575 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:ei2bg_human(display_long)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit gamma(gene name synonym)|uniprotkb:EIF2B3(gene name)|psi-mi:EIF2B3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_001160060.1|refseq:NP_065098.1|refseq:NP_001248347.1|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731|rcsb pdb:7D45|ensembl:ENST00000360403(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|ensembl:ENSG00000070785(gene)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0021766"(hippocampus development)|go:"GO:0032045"(guanyl-nucleotide exchange factor complex)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR025877|interpro:IPR029044|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:wGjFfKA+E5rYJfmocP6qcTQ9+SU9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:P11021 intact:EBI-6152249 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q53HC9 intact:EBI-6152249 intact:EBI-1055422|uniprotkb:O43179|uniprotkb:Q53S19|uniprotkb:Q53SG2|uniprotkb:D6W4Y1|ensembl:ENSP00000371559 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:eipr1_human(display_long)|uniprotkb:Golgi-associated retrograde protein-interacting protein(gene name synonym)|uniprotkb:EIPR1(gene name)|psi-mi:EIPR1(display_short)|uniprotkb:Endosome-associated recycling protein-interacting protein(gene name synonym)|uniprotkb:TSSC1(gene name synonym)|uniprotkb:Tumor-suppressing STF cDNA 1 protein(gene name synonym)|uniprotkb:Tumor-suppressing subchromosomal transferable fragment candidate gene 1 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_003301.1|ensembl:ENSG00000032389(gene)|ensembl:ENST00000382125(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032456"(endocytic recycling)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:1905281"(positive regulation of retrograde transport, endosome to Golgi)|go:"GO:2001137"(positive regulation of endocytic recycling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR040323|go:"GO:0005802"(trans-Golgi network) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:aPOAhiHUITd/B039ctxriPOgfeU9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q9BVC6 intact:EBI-6152249 intact:EBI-1057733|ensembl:ENSP00000227525|ensembl:ENSP00000443990 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:tm109_human(display_long)|uniprotkb:TMEM109(gene name)|psi-mi:TMEM109(display_short)|uniprotkb:Mitsugumin-23(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_076997.1|ensembl:ENSG00000110108(gene)|ensembl:ENST00000227525(transcript)|ensembl:ENST00000536171(transcript)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR039492|mint:Q9BVC6 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:KsibbFWmzuiZPpo4GqJikbMMaMQ9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:P68104 intact:EBI-6152249 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q5VTE0 intact:EBI-6152249 intact:EBI-877809 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:ef1a3_human(display_long)|uniprotkb:EEF1A1P5(gene name)|psi-mi:EEF1A1P5(display_short)|uniprotkb:Eukaryotic elongation factor 1 A-like 3(gene name synonym)|uniprotkb:EEF1AL3(gene name synonym)|uniprotkb:Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR031157|reactome:R-HSA-156842|interpro:IPR027417 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:3t6tj3i+3CKTC1NsrHyBkeoRK789606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q9BZW7 intact:EBI-6152249 intact:EBI-744794|uniprotkb:Q9BWX0|uniprotkb:Q8NEP0|ensembl:ENSP00000347161|ensembl:ENSP00000377123|ensembl:ENSP00000386956|uniprotkb:D3DVH7|uniprotkb:B7Z925 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:tsg10_human(display_long)|uniprotkb:CEP4L(gene name synonym)|uniprotkb:Testis development protein NYD-SP7(gene name synonym)|uniprotkb:TSGA10(gene name)|psi-mi:TSGA10(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 ensembl:ENSG00000135951(gene)|ensembl:ENST00000355053(transcript)|ensembl:ENST00000393483(transcript)|ensembl:ENST00000410001(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007283"(spermatogenesis)|interpro:IPR033323|mint:Q9BZW7|refseq:XP_011510239.1|refseq:XP_011510241.1|refseq:XP_011510242.1|refseq:XP_011510243.1|refseq:XP_011510244.1|refseq:XP_011510245.1|refseq:NP_079520.1|refseq:NP_878915.2|refseq:XP_016860528.1|refseq:XP_016860529.1|refseq:XP_016860530.1|refseq:XP_016860531.1|refseq:XP_016860532.1|refseq:XP_016860533.1|refseq:XP_016860534.1|refseq:XP_016860535.1|refseq:XP_016860536.1|refseq:XP_016860537.1|refseq:XP_005264080.1|refseq:XP_005264081.1|refseq:XP_005264082.1|refseq:XP_005264083.1|refseq:XP_005264084.1|refseq:XP_005264086.1|refseq:XP_006712844.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:DwMxOuwQfzz+CNSHN26fw48Gbpk9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:P28340 intact:EBI-6152249 intact:EBI-716569|uniprotkb:Q8NER3|uniprotkb:Q96H98|ensembl:ENSP00000406046|ensembl:ENSP00000472600|ensembl:ENSP00000473052 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:dpod1_human(display_long)|uniprotkb:3'-5' exodeoxyribonuclease(gene name synonym)|uniprotkb:DNA polymerase subunit delta p125(gene name synonym)|uniprotkb:POLD1(gene name)|psi-mi:POLD1(display_short)|uniprotkb:POLD(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_002682.2|refseq:XP_011525340.1|refseq:NP_001243778.1|ensembl:ENSG00000062822(gene)|ensembl:ENST00000599857(transcript)|ensembl:ENST00000601098(transcript)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0009411"(response to UV)|ensembl:ENST00000440232(transcript)|reactome:R-HSA-5651801|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-5358606|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0019899"(enzyme binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017964|interpro:IPR023211|interpro:IPR025687|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|mint:P28340|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|reactome:R-HSA-110314|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-2564830|reactome:R-HSA-5358565|refseq:XP_016882370.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:bJ5Q0xOzHga/zxMOBHkuXaFXeLw9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:P60660 intact:EBI-6152249 intact:EBI-300817|uniprotkb:P16475|uniprotkb:P24572|uniprotkb:P24573|uniprotkb:Q12790|ensembl:ENSP00000446955|ensembl:ENSP00000448101|uniprotkb:Q6IAZ0|uniprotkb:Q6IPY5|uniprotkb:Q561V9 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:myl6_human(display_long)|uniprotkb:MYL6(gene name)|psi-mi:MYL6(display_short)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6(gene name synonym)|uniprotkb:Myosin light chain alkali 3(gene name synonym)|uniprotkb:Myosin light chain 3(gene name synonym)|uniprotkb:17 kDa myosin light chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 ensembl:ENSG00000092841(gene)|ensembl:ENST00000548293(transcript)|ensembl:ENST00000550697(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016020"(membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P60660|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:NP_066299.2|refseq:NP_524147.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:LhE3NUqcuHlOla13C0vjnFZfzy89606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q01813 intact:EBI-6152249 intact:EBI-359022|uniprotkb:B3KS15|uniprotkb:Q5VSR7|uniprotkb:Q5VSR8|ensembl:ENSP00000370517 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:pfkap_human(display_long)|uniprotkb:PFKP(gene name)|psi-mi:PFKP(display_short)|uniprotkb:PFKF(gene name synonym)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme C(gene name synonym)|uniprotkb:6-phosphofructokinase type C(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_002618.1|ensembl:ENSG00000067057(gene)|ensembl:ENST00000381125(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:Q01813|rcsb pdb:4RH3|rcsb pdb:4U1R|rcsb pdb:4WL0|rcsb pdb:4XYJ|rcsb pdb:4XYK|rcsb pdb:4XZ2|reactome:R-HSA-70171|refseq:NP_001229268.1|dip:DIP-45850N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:GNmWbFrQsTMRdVphWG+3DK3wxaA9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q9HAV4 intact:EBI-6152249 intact:EBI-517949|uniprotkb:Q5JTE6|uniprotkb:Q96G48|uniprotkb:Q96HN3|uniprotkb:Q9BWM6|uniprotkb:Q9BZV5|uniprotkb:Q9H9M4|uniprotkb:Q9NT89|uniprotkb:Q9NW39|uniprotkb:Q9ULC9|ensembl:ENSP00000265351 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:xpo5_human(display_long)|uniprotkb:Ran-binding protein 21(gene name synonym)|uniprotkb:XPO5(gene name)|psi-mi:XPO5(display_short)|uniprotkb:KIAA1291(gene name synonym)|uniprotkb:RANBP21(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_065801.1|dip:DIP-34547N|rcsb pdb:5YU7|reactome:R-HSA-203927|ensembl:ENSG00000124571(gene)|ensembl:ENST00000265351(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016442"(RISC complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:1900370"(positive regulation of RNA interference)|go:"GO:1905172"(RISC complex binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040018|mint:Q9HAV4|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|rcsb pdb:3A6P|rcsb pdb:5YU6 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:wuUAxvyCl/u7CRtQLMK9McSoUrM9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q9UID3 intact:EBI-6152249 intact:EBI-2932923|ensembl:ENSP00000279281|uniprotkb:Q6PJV5|uniprotkb:Q7L8A6|uniprotkb:Q8WZ35|uniprotkb:Q96DF4|uniprotkb:Q96GR3 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:vps51_human(display_long)|uniprotkb:VPS51(gene name)|psi-mi:VPS51(display_short)|uniprotkb:ANG2(gene name synonym)|uniprotkb:Another new gene 2 protein(gene name synonym)|uniprotkb:C11orf2(gene name synonym)|uniprotkb:C11orf3(gene name synonym)|uniprotkb:FFR(gene name synonym)|uniprotkb:Protein fat-free homolog(gene name synonym)|uniprotkb:PP5382(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 ensembl:ENSG00000149823(gene)|ensembl:ENST00000279281(transcript)|go:"GO:0000938"(GARP complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006869"(lipid transport)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0055037"(recycling endosome)|go:"GO:1990745"(EARP complex)|interpro:IPR014812(Vps51/Vps67)|interpro:IPR016159(Cullin repeat-like)|mint:Q9UID3|rcsb pdb:4J2C|reactome:R-HSA-6811440|refseq:NP_037397.2|dip:DIP-60562N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:UGjZbNWrm7SCFNgZLmPRor03b+k9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q9UI10 intact:EBI-6152249 intact:EBI-2340132|uniprotkb:Q53RY7|uniprotkb:Q9UIQ9|uniprotkb:Q9UJ95|uniprotkb:Q5BJF4|uniprotkb:Q9UBG4|uniprotkb:Q9BUV9|ensembl:ENSP00000233552 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:ei2bd_human(display_long)|uniprotkb:EIF2B4(gene name)|psi-mi:EIF2B4(display_short)|uniprotkb:EIF2BD(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit delta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_001029288.1|refseq:NP_056451.3|refseq:NP_751945.2|refseq:NP_001305894.1|refseq:NP_001305895.1|refseq:NP_001305896.1|refseq:NP_001305897.1|ensembl:ENSG00000115211(gene)|ensembl:ENST00000347454(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006417"(regulation of translation)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0042552"(myelination)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR000649(Initiation factor 2B related)|interpro:IPR037171|interpro:IPR042529|mint:Q9UI10|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:ZCU4mIO5zkmBajIvBRe3b2PZINw9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q92552 intact:EBI-6152249 intact:EBI-2211879|uniprotkb:Q6P1S1|uniprotkb:B4DRT2|ensembl:ENSP00000261413 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:rt27_human(display_long)|uniprotkb:MRPS27(gene name)|psi-mi:MRPS27(display_short)|uniprotkb:KIAA0264(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS27(gene name synonym)|uniprotkb:Mitochondrial ribosomal protein S27(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_001273677.1|refseq:NP_055899.2|dip:DIP-44136N|ensembl:ENSG00000113048(gene)|ensembl:ENST00000261413(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0008283"(cell population proliferation)|go:"GO:0019843"(rRNA binding)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0097177"(mitochondrial ribosome binding)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019266|interpro:IPR034913|mint:Q92552|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:reHIDm6Of3ERJMBRxVlVntHyRlY9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q13144 intact:EBI-6152249 intact:EBI-4401110|uniprotkb:Q541Z1|uniprotkb:Q96D04|ensembl:ENSP00000497160 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:ei2be_human(display_long)|uniprotkb:EIF2B5(gene name)|psi-mi:EIF2B5(display_short)|uniprotkb:EIF2BE(gene name synonym)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_003898.2|ensembl:ENSG00000145191(gene)|ensembl:ENST00000648915(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0006413"(translational initiation)|go:"GO:0007568"(aging)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0010226"(response to lithium ion)|go:"GO:0014002"(astrocyte development)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0021766"(hippocampus development)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042552"(myelination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR011004(Trimeric LpxA-like)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR029044|interpro:IPR035543|interpro:IPR044123|rcsb pdb:3JUI|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731|go:"GO:0005634"(nucleus) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:158kR+Yjj/jXya10LiK3Xp0Fa5w9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:P17844 intact:EBI-6152249 intact:EBI-351962|uniprotkb:O75681|uniprotkb:Q53Y61|uniprotkb:B4DLW8|uniprotkb:E7ETL9|uniprotkb:B5BU21|uniprotkb:D3DU32|ensembl:ENSP00000225792|ensembl:ENSP00000403085|ensembl:ENSP00000463168|ensembl:ENSP00000464337|ensembl:ENSP00000504794 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:ddx5_human(display_long)|uniprotkb:HLR1(gene name synonym)|uniprotkb:DDX5(gene name)|psi-mi:DDX5(display_short)|uniprotkb:HELR(gene name synonym)|uniprotkb:G17P1(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_004387.1|refseq:NP_001307524.1|refseq:NP_001307525.1|dip:DIP-29844N|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P17844|rcsb pdb:3FE2|rcsb pdb:4A4D|reactome:R-HSA-3899300|reactome:R-HSA-72163|reactome:R-HSA-9018519|reactome:R-HSA-9682706|reactome:R-HSA-9694686|ensembl:ENST00000225792(transcript)|ensembl:ENST00000450599(transcript)|ensembl:ENST00000577922(transcript)|ensembl:ENST00000585111(transcript)|ensembl:ENST00000676785(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009299"(mRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|ensembl:ENSG00000108654(gene) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:BlaILQg90jqkI5+DdA0k5YTCGOo9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q14232 intact:EBI-6152249 intact:EBI-491065|uniprotkb:A6NLY9|uniprotkb:Q3SXP4|uniprotkb:B4DGX0|ensembl:ENSP00000416250 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:ei2ba_human(display_long)|uniprotkb:eIF-2B GDP-GTP exchange factor subunit alpha(gene name synonym)|uniprotkb:EIF2B1(gene name)|psi-mi:EIF2B1(display_short)|uniprotkb:EIF2BA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_001405.1|interpro:IPR037171|interpro:IPR042528|interpro:IPR042529|rcsb pdb:3ECS|rcsb pdb:6CAJ|rcsb pdb:6EZO|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6O81|rcsb pdb:6O85|rcsb pdb:6O9Z|rcsb pdb:7D43|rcsb pdb:7D44|rcsb pdb:7D45|rcsb pdb:7D46|rcsb pdb:7L70|rcsb pdb:7L7G|reactome:R-HSA-72731|ensembl:ENSG00000111361(gene)|ensembl:ENST00000424014(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0009408"(response to heat)|go:"GO:0009749"(response to glucose)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR000649(Initiation factor 2B related) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:HAThUj88pwaLd6kmAlO5s1xtntM9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P12792 uniprotkb:Q9Y265 intact:EBI-6152249 intact:EBI-353675|uniprotkb:P82276|uniprotkb:Q1KMR0|uniprotkb:Q53HK5|uniprotkb:Q53HL7|uniprotkb:Q53Y27|uniprotkb:Q9BSX9|uniprotkb:B2R5S0|ensembl:ENSP00000318297|ensembl:ENSP00000494621 psi-mi:nss_sfsv(display_long)|uniprotkb:NSS(gene name)|psi-mi:NSS(display_short) psi-mi:ruvb1_human(display_long)|uniprotkb:RUVBL1(gene name)|psi-mi:RUVBL1(display_short)|uniprotkb:NMP238(gene name synonym)|uniprotkb:TIP49(gene name synonym)|uniprotkb:TIP49A(gene name synonym)|uniprotkb:49 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49a(gene name synonym)|uniprotkb:Pontin 52(gene name synonym)|uniprotkb:Nuclear matrix protein 238(gene name synonym)|uniprotkb:54 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80H(gene name synonym)|uniprotkb:TIP60-associated protein 54-alpha(gene name synonym)|uniprotkb:INO80 complex subunit H(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:28292(sfsv)|taxid:28292(Sandfly fever sicilian virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159029|imex:IM-17331-59 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024376|interpro:IPR039434 refseq:NP_003698.1|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:Q9Y265|rcsb pdb:2C9O|rcsb pdb:2XSZ|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|reactome:R-HSA-201722|reactome:R-HSA-3214847|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5696394|reactome:R-HSA-606279|ensembl:ENSG00000175792(gene)|ensembl:ENSG00000284901(gene)|ensembl:ENST00000322623(transcript)|ensembl:ENST00000643444(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|refseq:NP_001306013.1|dip:DIP-29937N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/08/14 rogid:4i60V/wLrRr3JsdjVli7gDvbVTM28292 rogid:+FA/xQTUldQoWGRgad9U8vZpTHw9606 intact-crc:EC5D5C6C25F52BBF|rigid:gv1NGP0z2LVBkNIG98YHNExh3VM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:O00499 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-719094|uniprotkb:Q659B7|uniprotkb:O00297|uniprotkb:O00545|uniprotkb:O43867|uniprotkb:O60552|uniprotkb:O60553|uniprotkb:O60554|uniprotkb:O60555|uniprotkb:O75514|uniprotkb:O75515|uniprotkb:O75516|uniprotkb:O75517|uniprotkb:O75518|uniprotkb:Q92944|uniprotkb:Q99688|intact:EBI-1760307|intact:EBI-1965383|intact:EBI-28970933|ensembl:ENSP00000316779 psi-mi:polg_hcv77(display_long) psi-mi:bin1_human(display_long)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Box-dependent myc-interacting protein 1(gene name synonym)|uniprotkb:BIN1(gene name)|psi-mi:BIN1(display_short)|uniprotkb:AMPHL(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) ensembl:ENST00000259238|ensembl:ENSP00000259238|ensembl:ENSP00000316779|ensembl:ENST00000346226|ensembl:ENSP00000315411|ensembl:ENST00000348750|ensembl:ENSP00000259237|ensembl:ENST00000351659|ensembl:ENSP00000315388|ensembl:ENST00000352848|ensembl:ENSP00000315284|ensembl:ENST00000357970|ensembl:ENSP00000350654|ensembl:ENST00000376113|ensembl:ENSP00000365281|ensembl:ENST00000393040|ensembl:ENSP00000376760|ensembl:ENST00000393041|ensembl:ENSP00000376761|ensembl:ENST00000409400|ensembl:ENSP00000386797|refseq:NP_004296.1|refseq:NP_647593.1|refseq:NP_647594.1|refseq:NP_647595.1|refseq:NP_647596.1|refseq:NP_647597.1|refseq:NP_647598.1|refseq:NP_647599.1|refseq:NP_647600.1|refseq:NP_647601.1|refseq:NP_001307561.1|refseq:NP_001307562.1|refseq:NP_001307569.1|refseq:NP_001307570.1|refseq:NP_001307571.1|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|mint:O00499|rcsb pdb:1MUZ|rcsb pdb:1MV0|rcsb pdb:1MV3|rcsb pdb:2FIC|rcsb pdb:2RMY|rcsb pdb:2RND|rcsb pdb:5I22|reactome:R-HSA-8856828|go:"GO:0060987"(lipid tube)|ensembl:ENSG00000136717(gene)|ensembl:ENST00000316724(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006997"(nucleus organization)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030276"(clathrin binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048156"(tau protein binding)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|dip:DIP-41480N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:/3GFhR2reRqrmR19lWj5ErWP0N49606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:P61604 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-711483|uniprotkb:O95421|uniprotkb:Q04984|uniprotkb:Q53X54|ensembl:ENSP00000233893|uniprotkb:Q9UDH0 psi-mi:polg_hcv77(display_long) psi-mi:ch10_human(display_long)|uniprotkb:HSPE1(gene name)|psi-mi:HSPE1(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 10(gene name synonym)|uniprotkb:Early-pregnancy factor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) interpro:IPR020818|interpro:IPR037124|mint:P61604|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|reactome:R-HSA-9013408|ensembl:ENSG00000115541(gene)|ensembl:ENST00000233893(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011032(GroES-like)|interpro:IPR018369|refseq:NP_002148.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:BmnGoMnA2QIr3Dr0fElMtTgRztA9606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:P61956 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-473220|uniprotkb:P55855|uniprotkb:Q6IPZ6|ensembl:ENSP00000405965|uniprotkb:Q32Q42|uniprotkb:Q96HK1|intact:EBI-2512339|uniprotkb:B2R4I2 psi-mi:polg_hcv77(display_long) psi-mi:sumo2_human(display_long)|uniprotkb:SMT3 homolog 2(gene name synonym)|uniprotkb:Sentrin-2(gene name synonym)|uniprotkb:HSMT3(gene name synonym)|uniprotkb:SUMO-3(gene name synonym)|uniprotkb:SUMO2(gene name)|psi-mi:SUMO2(display_short)|uniprotkb:SMT3H2(gene name synonym)|uniprotkb:SMT3B(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) rcsb pdb:1Z5Q|rcsb pdb:2AWT|rcsb pdb:2CKH|rcsb pdb:2D07|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:P61956|rcsb pdb:1WM2|rcsb pdb:1WM3|rcsb pdb:1WZ0|rcsb pdb:2IO0|ensembl:ENSG00000188612(gene)|ensembl:ENST00000420826(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001005849.1|refseq:NP_008868.3|rcsb pdb:2IO3|rcsb pdb:6JXW|rcsb pdb:6JXX|reactome:R-HSA-196791|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5693607|reactome:R-HSA-5696395|rcsb pdb:5GHC|rcsb pdb:5D2M|rcsb pdb:5ELU|rcsb pdb:5EQL|rcsb pdb:5GHB|rcsb pdb:2IYD|rcsb pdb:2N1W|rcsb pdb:2N9E|rcsb pdb:2RPQ|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3ZO5|rcsb pdb:4BKG|rcsb pdb:4NPN|dip:DIP-29253N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:WgudlZhwtQbQInv29BniecTYGY89606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:P10599 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-594644|uniprotkb:B1ALW1|uniprotkb:O60744|uniprotkb:Q53X69|uniprotkb:Q96KI3|uniprotkb:Q9UDG5|intact:EBI-1042712|ensembl:ENSP00000363641 psi-mi:polg_hcv77(display_long) psi-mi:thio_human(display_long)|uniprotkb:ATL-derived factor(gene name synonym)|uniprotkb:Surface-associated sulphydryl protein(gene name synonym)|uniprotkb:TXN(gene name)|psi-mi:TXN(display_short)|uniprotkb:TRDX(gene name synonym)|uniprotkb:TRX(gene name synonym)|uniprotkb:TRX1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) refseq:NP_003320.2|refseq:NP_001231867.1|dip:DIP-6129N|ensembl:ENSG00000136810(gene)|ensembl:ENST00000374517(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006662"(glycerol ether metabolic process)|go:"GO:0009314"(response to radiation)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0047134"("protein-disulfide reductase (NAD(P)) activity")|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071731"(response to nitric oxide)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:2000170"(positive regulation of peptidyl-cysteine S-nitrosylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P10599|rcsb pdb:1AIU|rcsb pdb:1AUC|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1ERT|rcsb pdb:1ERU|rcsb pdb:1ERV|rcsb pdb:1ERW|rcsb pdb:1M7T|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1TRS|rcsb pdb:1TRU|rcsb pdb:1TRV|rcsb pdb:1TRW|rcsb pdb:1W1C|rcsb pdb:1W1E|rcsb pdb:2HSH|rcsb pdb:2HXK|rcsb pdb:2IFQ|rcsb pdb:2IIY|rcsb pdb:3E3E|rcsb pdb:3KD0|rcsb pdb:3M9J|rcsb pdb:3M9K|rcsb pdb:3QFA|rcsb pdb:3QFB|rcsb pdb:3TRX|rcsb pdb:4LL1|rcsb pdb:4LL4|rcsb pdb:4OO4|rcsb pdb:4OO5|rcsb pdb:4POK|rcsb pdb:4POL|rcsb pdb:4POM|rcsb pdb:4PUF|rcsb pdb:4TRX|rcsb pdb:5DQY|reactome:R-HSA-2559580|reactome:R-HSA-3299685|reactome:R-HSA-499943|reactome:R-HSA-5628897|reactome:R-HSA-5676934|reactome:R-HSA-844456|reactome:R-HSA-9617629|reactome:R-HSA-9660826 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:5u+iJJtwAwAKXljKHnpY8h5uRkQ9606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:P80723 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-358583|uniprotkb:D3DTD5|uniprotkb:O43596|uniprotkb:Q5U0S0|uniprotkb:Q9BWA5|uniprotkb:B4DJA8|ensembl:ENSP00000319281|ensembl:ENSP00000482066 psi-mi:polg_hcv77(display_long) psi-mi:basp1_human(display_long)|uniprotkb:BASP1(gene name)|psi-mi:BASP1(display_short)|uniprotkb:NAP22(gene name synonym)|uniprotkb:Neuronal axonal membrane protein NAP-22(gene name synonym)|uniprotkb:22 kDa neuronal tissue-enriched acidic protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) refseq:NP_006308.3|refseq:NP_001258535.1|ensembl:ENSG00000176788(gene)|ensembl:ENST00000322611(transcript)|ensembl:ENST00000616743(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0008406"(gonad development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030054"(cell junction)|go:"GO:0030426"(growth cone)|go:"GO:0031982"(vesicle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0060421"(positive regulation of heart growth)|go:"GO:0060539"(diaphragm development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072075"(metanephric mesenchyme development)|go:"GO:0072112"(glomerular visceral epithelial cell differentiation)|go:"GO:2001076"(positive regulation of metanephric ureteric bud development)|interpro:IPR008408(Brain acid soluble protein 1)|mint:P80723|reactome:R-HSA-9035034 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:X+L20HKimV3J+vLnQljg+x78+e09606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:Q00325 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34 psi-mi:polg_hcv77(display_long) psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325 - - crc64:78714C85931B22D5 figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:P06748 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930|ensembl:ENSP00000428755 psi-mi:polg_hcv77(display_long) psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) refseq:NP_002511.1|refseq:NP_954654.1|refseq:NP_001032827.1|dip:DIP-30932N|ensembl:ENSG00000181163(gene)|ensembl:ENST00000296930(transcript)|ensembl:ENST00000517671(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001652"(granular component)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006407"(rRNA export from nucleus)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019843"(rRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042255"(ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060699"(regulation of endoribonuclease activity)|go:"GO:0060735"(regulation of eIF2 alpha phosphorylation by dsRNA)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902629"(regulation of mRNA stability involved in cellular response to UV)|go:"GO:1902751"(positive regulation of cell cycle G2/M phase transition)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:Q15717 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-374260|uniprotkb:Q9BTT1|ensembl:ENSP00000385269|ensembl:ENSP00000472197|intact:EBI-6190219|uniprotkb:B4DVB8|uniprotkb:Q53XN6 psi-mi:polg_hcv77(display_long) psi-mi:elav1_human(display_long)|uniprotkb:ELAVL1(gene name)|psi-mi:ELAVL1(display_short)|uniprotkb:HUR(gene name synonym)|uniprotkb:Hu-antigen R(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) go:"GO:0006606"(protein import into nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035198"(miRNA binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|ensembl:ENSG00000066044(gene)|ensembl:ENST00000407627(transcript)|ensembl:ENST00000596459(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|refseq:NP_001410.2|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR034996|interpro:IPR035979|mint:Q15717|rcsb pdb:3HI9|rcsb pdb:4ED5|rcsb pdb:4EGL|rcsb pdb:4FXV|rcsb pdb:5SZW|rcsb pdb:6G2K|rcsb pdb:6GC5|rcsb pdb:6GD1|rcsb pdb:6GD2|rcsb pdb:6GD3|reactome:R-HSA-450520|reactome:R-HSA-72163|dip:DIP-31291N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:PciL5KuvP+2aUUv9cv7gWScgbw89606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:P12236 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-356254|ensembl:ENSP00000370808|uniprotkb:Q96C49 psi-mi:polg_hcv77(display_long) psi-mi:adt3_human(display_long)|uniprotkb:SLC25A6(gene name)|psi-mi:SLC25A6(display_short)|uniprotkb:ANT3(gene name synonym)|uniprotkb:CDABP0051(orf name)|uniprotkb:Adenine nucleotide translocator 3(gene name synonym)|uniprotkb:ADP,ATP carrier protein 3(gene name synonym)|uniprotkb:Solute carrier family 25 member 6(gene name synonym)|uniprotkb:ADP,ATP carrier protein, isoform T2(gene name synonym)|uniprotkb:AAC3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) ensembl:ENSG00000169100(gene)|ensembl:ENST00000381401(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12236|reactome:R-HSA-1268020|reactome:R-HSA-168277|reactome:R-HSA-180897|reactome:R-HSA-83936|refseq:NP_001627.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:K5zi7otVqbL4Z4NHyHB1nojLOTg9606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:P60174 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-717475|uniprotkb:D3DUS9|uniprotkb:P00938|uniprotkb:Q6IS07|uniprotkb:Q8WWD0|uniprotkb:Q96AG5|uniprotkb:Q6FHP9|uniprotkb:B7Z5D8|ensembl:ENSP00000379933 psi-mi:polg_hcv77(display_long) psi-mi:tpis_human(display_long)|uniprotkb:Triose-phosphate isomerase(gene name synonym)|uniprotkb:TPI1(gene name)|psi-mi:TPI1(display_short)|uniprotkb:TPI(gene name synonym)|uniprotkb:Methylglyoxal synthase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) refseq:NP_000356.1|refseq:NP_001152759.1|refseq:NP_001244955.1|ensembl:ENSG00000111669(gene)|ensembl:ENST00000396705(transcript)|go:"GO:0004807"(triose-phosphate isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0008929"(methylglyoxal synthase activity)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000652(Triosephosphate isomerase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR020861|interpro:IPR022896|interpro:IPR035990|mint:P60174|rcsb pdb:1HTI|rcsb pdb:1KLG|rcsb pdb:1KLU|rcsb pdb:1WYI|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2JK2|rcsb pdb:2VOM|rcsb pdb:4BR1|rcsb pdb:4E41|rcsb pdb:4POC|rcsb pdb:4POD|rcsb pdb:4UNK|rcsb pdb:4UNL|rcsb pdb:4ZVJ|rcsb pdb:6C2G|rcsb pdb:6D43|rcsb pdb:6NLH|rcsb pdb:6UP1|rcsb pdb:6UP5|rcsb pdb:6UP8|rcsb pdb:6UPF|reactome:R-HSA-70171|reactome:R-HSA-70263 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:FaLt6wGI1Bz2Z81gX35p7sOiMbE9606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:P06733 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6 psi-mi:polg_hcv77(display_long) psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:RmP7cr55H8ylcgBOEyivwljIE+09606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:O95292 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-1188298|uniprotkb:O95293|uniprotkb:Q9P0H0|uniprotkb:A2A2F2|ensembl:ENSP00000417175 psi-mi:polg_hcv77(display_long) psi-mi:vapb_human(display_long)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) refseq:NP_001182606.1|refseq:NP_004729.1|ensembl:ENSG00000124164(gene)|ensembl:ENST00000475243(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044790"(suppression of viral release by host)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:O95292|rcsb pdb:2MDK|rcsb pdb:3IKK|reactome:R-HSA-1660661|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|dip:DIP-39816N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:Q04941 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-608347|ensembl:ENSP00000365505|uniprotkb:A6NDT7|uniprotkb:Q32MM8 psi-mi:polg_hcv77(display_long) psi-mi:plp2_human(display_long)|uniprotkb:Intestinal membrane A4 protein(gene name synonym)|uniprotkb:Differentiation-dependent protein A4(gene name synonym)|uniprotkb:PLP2(gene name)|psi-mi:PLP2(display_short)|uniprotkb:A4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) ensembl:ENSG00000102007(gene)|ensembl:ENST00000376327(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006935"(chemotaxis)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019956"(chemokine binding)|interpro:IPR008253(Marvel)|refseq:NP_002659.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:mQOlRVDVw9W4XWAzftif1tnKEdU9606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:P29966 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-1047781|uniprotkb:E1P560|uniprotkb:Q2LA83|uniprotkb:Q5TDB7|ensembl:ENSP00000478061 psi-mi:polg_hcv77(display_long) psi-mi:marcs_human(display_long)|uniprotkb:Protein kinase C substrate, 80 kDa protein, light chain(gene name synonym)|uniprotkb:MARCKS(gene name)|psi-mi:MARCKS(display_short)|uniprotkb:MACS(gene name synonym)|uniprotkb:PRKCSL(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) refseq:NP_002347.5|ensembl:ENSG00000277443(gene)|ensembl:ENST00000612661(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042585"(germinal vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002101(Myristoylated alanine-rich C-kinase substrate MARCKS)|mint:P29966|reactome:R-HSA-399997 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:28v6sOqwULr0AvfJr7yAal9Yh1g9606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:Q06830 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-353193|ensembl:ENSP00000262746|ensembl:ENSP00000361152|ensembl:ENSP00000389047|ensembl:ENSP00000407034|ensembl:ENSP00000503140|uniprotkb:P35703|uniprotkb:Q2V576|uniprotkb:Q5T154|uniprotkb:Q5T155|uniprotkb:B5BU26|uniprotkb:D3DPZ8 psi-mi:polg_hcv77(display_long) psi-mi:prdx1_human(display_long)|uniprotkb:PRDX1(gene name)|psi-mi:PRDX1(display_short)|uniprotkb:PAGA(gene name synonym)|uniprotkb:PAGB(gene name synonym)|uniprotkb:TDPX2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Proliferation-associated gene protein(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor A(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) ensembl:ENSG00000117450(gene)|ensembl:ENST00000262746(transcript)|ensembl:ENST00000319248(transcript)|ensembl:ENST00000424390(transcript)|ensembl:ENST00000447184(transcript)|ensembl:ENST00000676549(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003723"(RNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042470"(melanosome)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q06830|rcsb pdb:2RII|rcsb pdb:3HY2|rcsb pdb:4XCS|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803|refseq:NP_001189360.1|refseq:NP_002565.1|refseq:NP_859047.1|refseq:NP_859048.1|dip:DIP-33152N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:ZM5ZXF900izH81QVqgd2+opwMrs9606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:P62937 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-437708|uniprotkb:P05092|uniprotkb:Q3KQW3|uniprotkb:Q6IBU5|uniprotkb:Q96IX3|uniprotkb:Q9BRU4|uniprotkb:Q9BTY9|uniprotkb:Q9UC61|uniprotkb:Q567Q0|ensembl:ENSP00000419425|uniprotkb:A8K220 psi-mi:polg_hcv77(display_long) psi-mi:ppia_human(display_long)|uniprotkb:Cyclophilin A(gene name synonym)|uniprotkb:Cyclosporin A-binding protein(gene name synonym)|uniprotkb:PPIA(gene name)|psi-mi:PPIA(display_short)|uniprotkb:CYPA(gene name synonym)|uniprotkb:Rotamase A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) refseq:NP_066953.1|interpro:IPR029000|mint:P62937|rcsb pdb:1AK4|rcsb pdb:1AWQ|rcsb pdb:1AWR|rcsb pdb:1AWS|rcsb pdb:1AWT|rcsb pdb:1AWU|rcsb pdb:1AWV|rcsb pdb:1BCK|rcsb pdb:1CWA|rcsb pdb:1CWB|rcsb pdb:1CWC|rcsb pdb:1CWF|rcsb pdb:1CWH|rcsb pdb:1CWI|rcsb pdb:1CWJ|rcsb pdb:1CWK|rcsb pdb:1CWL|rcsb pdb:1CWM|interpro:IPR024936|rcsb pdb:1CWO|rcsb pdb:1FGL|rcsb pdb:2N0T|rcsb pdb:2RMA|rcsb pdb:1M63|rcsb pdb:2RMB|rcsb pdb:2X25|rcsb pdb:2X2A|rcsb pdb:2X2C|rcsb pdb:2X2D|rcsb pdb:1M9C|rcsb pdb:1M9D|rcsb pdb:1M9E|rcsb pdb:2XGY|rcsb pdb:3CYH|rcsb pdb:3CYS|rcsb pdb:3K0M|rcsb pdb:3K0N|rcsb pdb:3K0O|rcsb pdb:3K0P|rcsb pdb:3K0Q|rcsb pdb:3K0R|rcsb pdb:3ODI|rcsb pdb:3ODL|rcsb pdb:1M9F|rcsb pdb:3RDD|rcsb pdb:1M9X|rcsb pdb:1M9Y|rcsb pdb:4CYH|rcsb pdb:4IPZ|rcsb pdb:4N1M|rcsb pdb:4N1N|rcsb pdb:1MF8|rcsb pdb:4N1O|rcsb pdb:4N1P|rcsb pdb:4N1Q|rcsb pdb:1MIK|rcsb pdb:1NMK|rcsb pdb:1OCA|rcsb pdb:1RMH|rcsb pdb:1VBS|rcsb pdb:1VBT|rcsb pdb:1W8L|rcsb pdb:1W8M|rcsb pdb:1W8V|rcsb pdb:1YND|rcsb pdb:1ZKF|rcsb pdb:2ALF|rcsb pdb:2CPL|rcsb pdb:2CYH|rcsb pdb:2MS4|rcsb pdb:2MZU|rcsb pdb:4N1R|rcsb pdb:4N1S|rcsb pdb:4YUG|rcsb pdb:4YUH|refseq:NP_001287910.1|reactome:R-HSA-210991|reactome:R-HSA-6798695|reactome:R-HSA-8950505|reactome:R-HSA-2025928|ensembl:ENSG00000196262(gene)|ensembl:ENST00000468812(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006915"(apoptotic process)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016020"(membrane)|go:"GO:0019076"(viral release from host cell)|go:"GO:0030168"(platelet activation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0031982"(vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046790"(virion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060352"(cell adhesion molecule production)|go:"GO:0061944"(negative regulation of protein K48-linked ubiquitination)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903901"(negative regulation of viral life cycle)|go:"GO:1904399"(heparan sulfate binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|go:"GO:0005178"(integrin binding)|rcsb pdb:4YUI|rcsb pdb:4YUJ|rcsb pdb:4YUK|rcsb pdb:4YUL|rcsb pdb:4YUM|rcsb pdb:4YUN|rcsb pdb:4YUO|rcsb pdb:4YUP|rcsb pdb:5CYH|rcsb pdb:5F66|rcsb pdb:5FJB|rcsb pdb:5KUL|rcsb pdb:5KUN|rcsb pdb:5KUO|rcsb pdb:5KUQ|rcsb pdb:5KUR|rcsb pdb:5KUS|rcsb pdb:5KUU|rcsb pdb:5KUV|rcsb pdb:5KUW|rcsb pdb:5KUZ|rcsb pdb:5KV0|rcsb pdb:5KV1|rcsb pdb:5KV2|rcsb pdb:5KV3|rcsb pdb:5KV4|rcsb pdb:5KV5|rcsb pdb:5KV6|rcsb pdb:5KV7|rcsb pdb:5LUD|rcsb pdb:5NOQ|rcsb pdb:5NOR|rcsb pdb:5NOT|rcsb pdb:5NOU|rcsb pdb:5NOV|rcsb pdb:5NOW|rcsb pdb:5NOX|rcsb pdb:5NOY|rcsb pdb:5NOZ|rcsb pdb:5T9U|rcsb pdb:5T9W|rcsb pdb:5T9Z|rcsb pdb:5TA2|rcsb pdb:5TA4|rcsb pdb:5WC7|rcsb pdb:6BTA|rcsb pdb:6GJI|rcsb pdb:6GJJ|rcsb pdb:6GJL|rcsb pdb:6GJM|rcsb pdb:6GJN|rcsb pdb:6GJP|rcsb pdb:6GJR|rcsb pdb:6GJY|rcsb pdb:6GS6|rcsb pdb:6I42|rcsb pdb:6U5C|rcsb pdb:6U5D|rcsb pdb:6U5E|rcsb pdb:6U5G|rcsb pdb:6X3R|rcsb pdb:6X3Y|rcsb pdb:5NOS|rcsb pdb:6X4N|rcsb pdb:6X4O|rcsb pdb:6X4P|rcsb pdb:6X4Q|rcsb pdb:6Y9V|rcsb pdb:6Y9W|rcsb pdb:6Y9X|rcsb pdb:6Y9Y|rcsb pdb:6Y9Z|rcsb pdb:6ZDJ|rcsb pdb:7ABT|reactome:R-HSA-114608|reactome:R-HSA-162585|reactome:R-HSA-162588|reactome:R-HSA-162592|reactome:R-HSA-162594|reactome:R-HSA-164516|reactome:R-HSA-164525|reactome:R-HSA-173107|rcsb pdb:6X4M|reactome:R-HSA-175474|reactome:R-HSA-180689|dip:DIP-6080N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:dr4EVxcO+sqTPBqsQcydRn+rHoo9606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:P16949 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-445909|uniprotkb:A2A2D1|uniprotkb:B7Z8N4|uniprotkb:D3DPJ5|uniprotkb:B2R4E7|ensembl:ENSP00000350531|ensembl:ENSP00000363409|ensembl:ENSP00000382633|ensembl:ENSP00000387858 psi-mi:polg_hcv77(display_long) psi-mi:stmn1_human(display_long)|uniprotkb:Phosphoprotein p19(gene name synonym)|uniprotkb:Leukemia-associated phosphoprotein p18(gene name synonym)|uniprotkb:Oncoprotein 18(gene name synonym)|uniprotkb:pp17(gene name synonym)|uniprotkb:Prosolin(gene name synonym)|uniprotkb:Metablastin(gene name synonym)|uniprotkb:Protein Pr22(gene name synonym)|uniprotkb:STMN1(gene name)|psi-mi:STMN1(display_short)|uniprotkb:LAP18(gene name synonym)|uniprotkb:OP18(gene name synonym)|uniprotkb:C1orf215(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) refseq:NP_001138926.1|refseq:NP_005554.1|refseq:NP_981944.1|refseq:NP_981946.1|ensembl:ENST00000357865(transcript)|ensembl:ENST00000374291(transcript)|ensembl:ENST00000399728(transcript)|ensembl:ENST00000455785(transcript)|go:"GO:0000281"(mitotic cytokinesis)|ensembl:ENSG00000117632(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0009615"(response to virus)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043005"(neuron projection)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|mint:P16949|interpro:IPR000956(Stathmin)|interpro:IPR030514|interpro:IPR036002|reactome:R-HSA-1251985 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:gew+NqUuLLolCLCXOyXIZkRieIs9606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:P05455 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-358037|ensembl:ENSP00000260956|ensembl:ENSP00000386636|uniprotkb:Q15367|uniprotkb:Q53XJ4 psi-mi:polg_hcv77(display_long) psi-mi:la_human(display_long)|uniprotkb:SSB(gene name)|psi-mi:SSB(display_short)|uniprotkb:Sjoegren syndrome type B antigen(gene name synonym)|uniprotkb:La ribonucleoprotein(gene name synonym)|uniprotkb:La autoantigen(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) refseq:NP_003133.1|ensembl:ENSG00000138385(gene)|ensembl:ENST00000260956(transcript)|ensembl:ENST00000409333(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0008033"(tRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008334"(histone mRNA metabolic process)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071045"(nuclear histone mRNA catabolic process)|refseq:NP_001281074.1|dip:DIP-29750N|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|mint:P05455|rcsb pdb:1OWX|rcsb pdb:1S79|rcsb pdb:1S7A|rcsb pdb:1YTY|rcsb pdb:1ZH5|rcsb pdb:2VOD|rcsb pdb:2VON|rcsb pdb:2VOO|rcsb pdb:2VOP|reactome:R-HSA-73980|reactome:R-HSA-749476 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:Lgpr3jgLWGk3AZzPwjB1swJRsoQ9606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:P55209 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-356392|ensembl:ENSP00000376947|ensembl:ENSP00000477538|uniprotkb:B3KV44|uniprotkb:B3KNT8 psi-mi:polg_hcv77(display_long) psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) ensembl:ENSG00000187109(gene)|ensembl:ENST00000393263(transcript)|ensembl:ENST00000618691(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|refseq:NP_004528.1|refseq:NP_631946.1|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:P10809 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-352528|ensembl:ENSP00000340019|ensembl:ENSP00000373620|ensembl:ENSP00000396460|ensembl:ENSP00000402478|ensembl:ENSP00000412227|ensembl:ENSP00000412717|ensembl:ENSP00000414446|ensembl:ENSP00000503139|ensembl:ENSP00000503894|uniprotkb:Q38L19|uniprotkb:B2R5M6|uniprotkb:Q9UCR6|uniprotkb:B7Z712 psi-mi:polg_hcv77(display_long) psi-mi:ch60_human(display_long)|uniprotkb:HSPD1(gene name)|psi-mi:HSPD1(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:P60 lymphocyte protein(gene name synonym)|uniprotkb:HuCHA60(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) refseq:NP_002147.2|refseq:NP_955472.1|ensembl:ENSG00000144381(gene)|ensembl:ENST00000345042(transcript)|ensembl:ENST00000388968(transcript)|ensembl:ENST00000418022(transcript)|ensembl:ENST00000426480(transcript)|ensembl:ENST00000428204(transcript)|ensembl:ENST00000439605(transcript)|ensembl:ENST00000452200(transcript)|ensembl:ENST00000677913(transcript)|ensembl:ENST00000678761(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051604"(protein maturation)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P10809|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|rcsb pdb:7AZP|reactome:R-HSA-1268020|reactome:R-HSA-8869496|dip:DIP-58N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:syB2vt66Cpr2mJROfbxoPevoiRE9606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:O94966 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-2511895|ensembl:ENSP00000381863|uniprotkb:Q641Q9|uniprotkb:Q86XV9|uniprotkb:Q3KQW4|uniprotkb:A6H8U2|uniprotkb:Q6NZY8|uniprotkb:A5PKX8|uniprotkb:B4DGT3|uniprotkb:E7ETS0|uniprotkb:E9PEG8|uniprotkb:B4DTZ0|uniprotkb:E7EN22 psi-mi:polg_hcv77(display_long) psi-mi:ubp19_human(display_long)|uniprotkb:USP19(gene name)|psi-mi:USP19(display_short)|uniprotkb:KIAA0891(gene name synonym)|uniprotkb:ZMYND9(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 19(gene name synonym)|uniprotkb:Deubiquitinating enzyme 19(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 9(gene name synonym)|uniprotkb:Ubiquitin thioesterase 19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) ensembl:ENSG00000172046(gene)|ensembl:ENST00000398888(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0090068"(positive regulation of cell cycle process)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1904292"(regulation of ERAD pathway)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|mint:O94966|rcsb pdb:1WH0|rcsb pdb:4X3G|rcsb pdb:6K7W|rcsb pdb:6KHV|rcsb pdb:6KQV|reactome:R-HSA-5689880|refseq:NP_001186089.1|refseq:NP_001186090.1|refseq:NP_001186091.1|refseq:NP_006668.1|refseq:XP_005264888.1|refseq:XP_016861115.1|refseq:XP_016861122.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:5U3FuLQ44MsWtu7o/3bY7seGC3M9606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:P11021 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:polg_hcv77(display_long) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:Q14318 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-724839|uniprotkb:Q53GU3|uniprotkb:Q7Z349|uniprotkb:Q86YK6|ensembl:ENSP00000222308|ensembl:ENSP00000472302|uniprotkb:C8C9T5 psi-mi:polg_hcv77(display_long) psi-mi:fkbp8_human(display_long)|uniprotkb:FK506-binding protein 8(gene name synonym)|uniprotkb:38 kDa FK506-binding protein(gene name synonym)|uniprotkb:FKBPR38(gene name synonym)|uniprotkb:FKBP8(gene name)|psi-mi:FKBP8(display_short)|uniprotkb:FKBP38(gene name synonym)|uniprotkb:Rotamase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) refseq:NP_036313.3|refseq:NP_001295302.1|go:"GO:0001708"(cell fate specification)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0046872"(metal ion binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|mint:Q14318|ensembl:ENSG00000105701(gene)|rcsb pdb:2AWG|rcsb pdb:2D9F|rcsb pdb:2F2D|rcsb pdb:2MF9|rcsb pdb:3EY6|rcsb pdb:5MGX|reactome:R-HSA-5689880|ensembl:ENST00000222308(transcript)|ensembl:ENST00000596558(transcript)|refseq:XP_011526165.1|dip:DIP-42200N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:CpZqwry5szPluwNMwWXshCIMUvY9606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:Q9H8S9 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-748229|uniprotkb:Q53S34|uniprotkb:Q9H3T5|uniprotkb:Q9HAI0|uniprotkb:Q9NVE2|ensembl:ENSP00000379364 psi-mi:polg_hcv77(display_long) psi-mi:mob1a_human(display_long)|uniprotkb:MOB1A(gene name)|psi-mi:MOB1A(display_short)|uniprotkb:C2orf6(gene name synonym)|uniprotkb:MOB4B(gene name synonym)|uniprotkb:MOBK1B(gene name synonym)|uniprotkb:MOBKL1B(gene name synonym)|uniprotkb:Mob1 alpha(gene name synonym)|uniprotkb:Mob1 homolog 1B(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 1B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) refseq:NP_001304039.1|refseq:NP_001304040.1|refseq:NP_001304041.1|refseq:NP_060691.2|ensembl:ENSG00000114978(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0035329"(hippo signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9H8S9|rcsb pdb:1PI1|rcsb pdb:4J1V|rcsb pdb:4JIZ|rcsb pdb:5BRK|rcsb pdb:5BRM|rcsb pdb:5TWF|rcsb pdb:5TWG|rcsb pdb:5TWH|rcsb pdb:5XQZ|rcsb pdb:6MCP|rcsb pdb:6MCQ|reactome:R-HSA-2028269|ensembl:ENST00000396049(transcript)|dip:DIP-36594N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:Gup4pRYJH3cfC6+XkgI27yiF7g89606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:Q9P0L0 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880 psi-mi:polg_hcv77(display_long) psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:Q7L9L4 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-2558745|uniprotkb:B2R8U6|uniprotkb:Q8IY23|ensembl:ENSP00000310189|uniprotkb:B4DRY3 psi-mi:polg_hcv77(display_long) psi-mi:mob1b_human(display_long)|uniprotkb:MOB1B(gene name)|psi-mi:MOB1B(display_short)|uniprotkb:MOB4A(gene name synonym)|uniprotkb:MOBKL1A(gene name synonym)|uniprotkb:Mob1 homolog 1A(gene name synonym)|uniprotkb:Mob1B(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) refseq:NP_775739.1|ensembl:ENSG00000173542(gene)|ensembl:ENST00000309395(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0019209"(kinase activator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0035329"(hippo signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q7L9L4|reactome:R-HSA-2028269|refseq:NP_001231695.1|refseq:XP_005265766.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:+OqB7l7K1Oax2Aj96idIAas4qT49606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:P14174 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-372712|uniprotkb:A5Z1R8|uniprotkb:B2R4S3|uniprotkb:Q6FHV0|uniprotkb:Q2V4Y5|ensembl:ENSP00000215754|ensembl:ENSP00000482779 psi-mi:polg_hcv77(display_long) psi-mi:mif_human(display_long)|uniprotkb:MIF(gene name)|psi-mi:MIF(display_short)|uniprotkb:MMIF(gene name synonym)|uniprotkb:GLIF(gene name synonym)|uniprotkb:Phenylpyruvate tautomerase(gene name synonym)|uniprotkb:Glycosylation-inhibiting factor(gene name synonym)|uniprotkb:L-dopachrome tautomerase(gene name synonym)|uniprotkb:L-dopachrome isomerase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) refseq:NP_002406.1|ensembl:ENST00000215754(transcript)|ensembl:ENST00000613839(transcript)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004167"(dopachrome isomerase activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|ensembl:ENSG00000276701(gene)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0010760"(negative regulation of macrophage chemotaxis)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031982"(vesicle)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|ensembl:ENSG00000240972(gene)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045087"(innate immune response)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050178"(phenylpyruvate tautomerase activity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001398(Macrophage migration inhibitory factor)|interpro:IPR014347(Tautomerase)|interpro:IPR019829|mint:P14174|rcsb pdb:1CGQ|rcsb pdb:1GCZ|rcsb pdb:1GD0|rcsb pdb:1GIF|rcsb pdb:1LJT|rcsb pdb:1MIF|rcsb pdb:1P1G|rcsb pdb:2OOH|rcsb pdb:2OOW|rcsb pdb:2OOZ|rcsb pdb:3B9S|rcsb pdb:3CE4|rcsb pdb:3DJH|rcsb pdb:3DJI|rcsb pdb:3HOF|rcsb pdb:3IJG|rcsb pdb:3IJJ|rcsb pdb:3JSF|rcsb pdb:3JSG|rcsb pdb:3JTU|rcsb pdb:3L5P|rcsb pdb:3L5R|rcsb pdb:3L5S|rcsb pdb:3L5T|rcsb pdb:3L5U|rcsb pdb:3L5V|rcsb pdb:3SMB|rcsb pdb:3SMC|rcsb pdb:3U18|rcsb pdb:3WNR|rcsb pdb:3WNS|rcsb pdb:3WNT|rcsb pdb:4ETG|rcsb pdb:4EUI|rcsb pdb:4EVG|rcsb pdb:4F2K|rcsb pdb:4GRN|rcsb pdb:4GRO|rcsb pdb:4GRP|rcsb pdb:4GRQ|rcsb pdb:4GRR|rcsb pdb:4GRU|rcsb pdb:4GUM|rcsb pdb:4K9G|rcsb pdb:4OSF|rcsb pdb:4OYQ|rcsb pdb:4P01|rcsb pdb:4P0H|rcsb pdb:4PKK|rcsb pdb:4PKZ|rcsb pdb:4PLU|rcsb pdb:4TRF|rcsb pdb:4TRU|rcsb pdb:4WR8|rcsb pdb:4WRB|rcsb pdb:4XX7|rcsb pdb:4XX8|rcsb pdb:4Z15|rcsb pdb:4Z1T|rcsb pdb:4Z1U|rcsb pdb:5B4O|rcsb pdb:5BS9|rcsb pdb:5BSC|rcsb pdb:5BSI|rcsb pdb:5BSJ|rcsb pdb:5EIZ|rcsb pdb:5HVS|rcsb pdb:5HVT|rcsb pdb:5HVV|rcsb pdb:5J7P|rcsb pdb:5J7Q|rcsb pdb:5UMJ|rcsb pdb:5UMK|rcsb pdb:5UZY|rcsb pdb:5V70|rcsb pdb:5V73|rcsb pdb:5XEJ|rcsb pdb:1CA7|rcsb pdb:6B1C|rcsb pdb:6B1K|rcsb pdb:6B2C|rcsb pdb:6BG6|rcsb pdb:6BG7|rcsb pdb:6CB5|rcsb pdb:6CBF|rcsb pdb:6CBG|rcsb pdb:6FVE|rcsb pdb:6FVH|rcsb pdb:6OY8|rcsb pdb:6OYB|rcsb pdb:6OYE|rcsb pdb:6OYG|rcsb pdb:6PEG|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-8950505|rcsb pdb:6CBH|dip:DIP-31137N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:Vk+Sfaz5c59y8dKKJ4Qn+7fjwvQ9606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:P05141 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:polg_hcv77(display_long) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:Q562R1 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-1773495|uniprotkb:Q562R2|uniprotkb:Q562S9|uniprotkb:Q562X8|uniprotkb:B2RPJ1|ensembl:ENSP00000416706 psi-mi:polg_hcv77(display_long) psi-mi:actbl_human(display_long)|uniprotkb:ACTBL2(gene name)|psi-mi:ACTBL2(display_short)|uniprotkb:Kappa-actin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) refseq:NP_001017992.1|ensembl:ENSG00000169067(gene)|ensembl:ENST00000423391(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0007409"(axonogenesis)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0045202"(synapse)|go:"GO:0048870"(cell motility)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:Q562R1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:GTzKP5YRJGH8ocAJW0WEsdQFEdc9606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:P68371 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289 psi-mi:polg_hcv77(display_long) psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:P07437 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:polg_hcv77(display_long) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:O14654 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-356594|ensembl:ENSP00000505547 psi-mi:polg_hcv77(display_long) psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27958 uniprotkb:Q9H7B4 intact:EBI-706378|uniprotkb:O36579|uniprotkb:O36608|uniprotkb:O36609|uniprotkb:O36610 intact:EBI-347919|ensembl:ENSP00000419184|uniprotkb:Q86TL8|uniprotkb:Q8N5Z6|uniprotkb:Q96AI5|uniprotkb:B1AN38|uniprotkb:A8K0P0 psi-mi:polg_hcv77(display_long) psi-mi:smyd3_human(display_long)|uniprotkb:SMYD3(gene name)|psi-mi:SMYD3(display_short)|uniprotkb:ZMYND1(gene name synonym)|uniprotkb:ZNFN3A1(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 1(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:63746(HCV77)|taxid:63746("Hepatitis C virus genotype 1a (isolate H77)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159185|imex:IM-17331-60 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:6WO5|rcsb pdb:6WOQ|rcsb pdb:5FGB|rcsb pdb:5FGC|rcsb pdb:5EOC|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011492(DEAD box, Flavivirus)|interpro:IPR002521(Hepatitis C virus core protein)|interpro:IPR002522(Hepatitis C virus capsid protein)|interpro:IPR002519(Hepatitis C virus envelope glycoprotein E1)|interpro:IPR002531(Hepatitis C virus non-structural protein E2/NS1)|interpro:IPR000745(Hepatitis C virus non-structural protein NS4a)|interpro:IPR001490(Hepatitis C virus non-structural protein NS4b)|interpro:IPR002868(Hepatitis C virus non-structural 5a protein)|interpro:IPR013193(Hepatitis C virus non-structural 5a, region 1b)|interpro:IPR024350|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002518(Peptidase C18, hepatitis C virus endopeptidase 2)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR004109(Peptidase S29, hepatitus C polyprotein NS3)|interpro:IPR007094(RNA-directed RNA polymerase, positive-strand RNA eukaryotic virus)|interpro:IPR002166(RNA dependent RNA polymerase, hepatitis C virus)|interpro:IPR013192(Zinc finger, hepatitis C virus non-structural 5a-type)|rcsb pdb:4MWF|rcsb pdb:4Q0X|rcsb pdb:4XVJ|interpro:IPR042205|interpro:IPR042209|rcsb pdb:5YXN|rcsb pdb:5YXU|rcsb pdb:1A1R|rcsb pdb:1A1V|rcsb pdb:1CWX|rcsb pdb:1HEI|rcsb pdb:1JR6|rcsb pdb:1N1L|rcsb pdb:1ONB|rcsb pdb:1R7C|rcsb pdb:1R7D|rcsb pdb:1R7E|rcsb pdb:1R7F|rcsb pdb:1R7G|rcsb pdb:1RGQ|rcsb pdb:2F9V|rcsb pdb:2HD0|rcsb pdb:2JXF|rcsb pdb:2KDR|rcsb pdb:2O8M|rcsb pdb:2OBO|rcsb pdb:2OBQ|rcsb pdb:4JZN|rcsb pdb:4JZO|rcsb pdb:2OC0|rcsb pdb:2OC1|rcsb pdb:2OC7|rcsb pdb:2OC8|rcsb pdb:2OIN|rcsb pdb:2P59|rcsb pdb:2XI2|rcsb pdb:2XI3|rcsb pdb:4N0Y|rcsb pdb:2N1P|rcsb pdb:2A4R|rcsb pdb:2XNI|interpro:IPR043128|interpro:IPR027417|rcsb pdb:2QV1|rcsb pdb:4CL1|rcsb pdb:5ERW|rcsb pdb:4Z0X|reactome:R-HSA-8854214|interpro:IPR038170|interpro:IPR038568|rcsb pdb:5JZI|rcsb pdb:3RC4|rcsb pdb:3RC5|rcsb pdb:6UYD|rcsb pdb:6BQJ|rcsb pdb:6BQK|rcsb pdb:6BZU|rcsb pdb:6BZV|rcsb pdb:6BZW|rcsb pdb:6BZY|interpro:IPR043502|interpro:IPR043504|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005216"(ion channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010694"(positive regulation of alkaline phosphatase activity)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019031"(viral envelope)|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0019054"(modulation by virus of host cellular process)|go:"GO:0019056"(modulation by virus of host transcription)|go:"GO:0019082"(viral protein processing)|go:"GO:0019087"(transformation of host cell by virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033644"(host cell membrane)|go:"GO:0033647"(host intracellular organelle)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034136"(negative regulation of toll-like receptor 2 signaling pathway)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034156"(negative regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035663"(Toll-like receptor 2 binding)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039545"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity)|go:"GO:0039547"(suppression by virus of host TRAF activity)|go:"GO:0039560"(suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039613"(suppression by virus of host protein phosphorylation)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039653"(suppression by virus of host transcription)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0039714"(cytoplasmic viral factory)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044167"(host cell endoplasmic reticulum membrane)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044186"(host cell lipid droplet)|go:"GO:0044191"(host cell mitochondrial membrane)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0044833"(modulation by virus of host protein transport)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046762"(viral budding from endoplasmic reticulum membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0050689"(negative regulation of defense response to virus by host)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060590"(ATPase regulator activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0098670"(entry receptor-mediated virion attachment to host cell)|go:"GO:0098671"(adhesion receptor-mediated virion attachment to host cell)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1900369"(negative regulation of RNA interference)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903301"(positive regulation of hexokinase activity)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990216"(positive regulation by symbiont of host transcription)|go:"GO:1990254"(keratin filament binding) ensembl:ENSG00000185420(gene)|ensembl:ENST00000490107(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0014904"(myotube cell development)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR025805|interpro:IPR044420|mint:Q9H7B4|rcsb pdb:3MEK|rcsb pdb:3OXF|rcsb pdb:3OXG|rcsb pdb:3OXL|rcsb pdb:3PDN|rcsb pdb:3QWP|rcsb pdb:3RU0|rcsb pdb:5CCL|rcsb pdb:5CCM|rcsb pdb:5EX0|rcsb pdb:5EX3|rcsb pdb:5HI7|rcsb pdb:5HQ8|rcsb pdb:5V37|rcsb pdb:5XXG|rcsb pdb:5XXJ|rcsb pdb:5YJO|rcsb pdb:6IJL|rcsb pdb:6O9O|rcsb pdb:6P6G|rcsb pdb:6P6K|rcsb pdb:5XXD|rcsb pdb:6P7Z|rcsb pdb:6PAF|rcsb pdb:6YUH|rcsb pdb:7BJ1|reactome:R-HSA-3214841|refseq:XP_011542559.1|refseq:NP_001161212.1|refseq:NP_073580.1|dip:DIP-32653N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:JTO6thKKerqFLVzcNGjB9C/ZPcQ63746 rogid:gKISZLHkhKTIVn2O646c4OQhLzc9606 intact-crc:C6C63B7553FF35F6|rigid:LIJY3gNH6gue2/iRwxGzBPEPIKY false tandem tag:?-?|sufficient binding region:1973-2420 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A9YDK9 uniprotkb:Q02539 intact:EBI-6152521 intact:EBI-932603|uniprotkb:Q3MJ34|ensembl:ENSP00000244573 psi-mi:a9ydk9_bvdv(display_long)|uniprotkb:Npro(gene name)|psi-mi:Npro(display_short) psi-mi:h11_human(display_long)|uniprotkb:H1-1(gene name)|psi-mi:H1-1(display_short)|uniprotkb:H1F1(gene name synonym)|uniprotkb:HIST1H1A(gene name synonym)|uniprotkb:Histone H1a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11099(bvdv)|taxid:11099(Bovine viral diarrhea virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159292|imex:IM-17331-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|interpro:IPR042542|interpro:IPR008751(Peptidase C53, pestivirus Npro) refseq:NP_005316.1|ensembl:ENSG00000124610(gene)|ensembl:ENST00000244573(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q02539|reactome:R-HSA-140342|reactome:R-HSA-2559584 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:SkaBrVIZl+9hhFmOaYAlmmudBFM11099 rogid:4u8P8jFM3onWx43+SxL320urjhk9606 intact-crc:D2828ED65E17C666|rigid:weNN7e1uIWb6ucMB0syUNP7IbiM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A9YDK9 uniprotkb:Q15369 intact:EBI-6152521 intact:EBI-301231|uniprotkb:Q567Q6|ensembl:ENSP00000284811|ensembl:ENSP00000428074|ensembl:ENSP00000428171|ensembl:ENSP00000428334|ensembl:ENSP00000429596|ensembl:ENSP00000429906|ensembl:ENSP00000478121|uniprotkb:E5RGD9 psi-mi:a9ydk9_bvdv(display_long)|uniprotkb:Npro(gene name)|psi-mi:Npro(display_short) psi-mi:eloc_human(display_long)|uniprotkb:ELOC(gene name)|psi-mi:ELOC(display_short)|uniprotkb:Elongin 15 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit C(gene name synonym)|uniprotkb:SIII p15(gene name synonym)|uniprotkb:TCEB1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11099(bvdv)|taxid:11099(Bovine viral diarrhea virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159292|imex:IM-17331-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|interpro:IPR042542|interpro:IPR008751(Peptidase C53, pestivirus Npro) refseq:NP_005639.1|refseq:NP_001191786.1|refseq:NP_001191787.1|refseq:NP_001191788.1|refseq:NP_001191789.1|refseq:NP_001191790.1|refseq:NP_001191791.1|refseq:NP_001191792.1|refseq:NP_001191793.1|ensembl:ENSG00000154582(gene)|ensembl:ENST00000284811(transcript)|ensembl:ENST00000518127(transcript)|ensembl:ENST00000519487(transcript)|ensembl:ENST00000520242(transcript)|ensembl:ENST00000522337(transcript)|ensembl:ENST00000523815(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|mint:Q15369|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|ensembl:ENST00000622804(transcript)|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:4WQO|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6GFY|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7N|rcsb pdb:6SIS|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-167200|refseq:XP_011515882.1|refseq:XP_011515883.1|dip:DIP-29571N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:SkaBrVIZl+9hhFmOaYAlmmudBFM11099 rogid:Ngvkh3YoddZoutF3Vgwdi2b6xz49606 intact-crc:D2828ED65E17C666|rigid:weNN7e1uIWb6ucMB0syUNP7IbiM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A9YDK9 uniprotkb:Q9BRZ2 intact:EBI-6152521 intact:EBI-1048636|uniprotkb:Q6PJS5|uniprotkb:Q86VT6|uniprotkb:Q8N2H8|uniprotkb:Q8NAC0|uniprotkb:Q9H031|intact:EBI-2129929|ensembl:ENSP00000305161 psi-mi:a9ydk9_bvdv(display_long)|uniprotkb:Npro(gene name)|psi-mi:Npro(display_short) psi-mi:tri56_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase TRIM56(gene name synonym)|uniprotkb:RING finger protein 109(gene name synonym)|uniprotkb:TRIM56(gene name)|psi-mi:TRIM56(display_short)|uniprotkb:RNF109(gene name synonym)|uniprotkb:Tripartite motif-containing protein 56(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11099(bvdv)|taxid:11099(Bovine viral diarrhea virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159292|imex:IM-17331-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|interpro:IPR042542|interpro:IPR008751(Peptidase C53, pestivirus Npro) refseq:NP_112223.1|refseq:XP_011514891.1|ensembl:ENSG00000169871(gene)|ensembl:ENST00000306085(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0034340"(response to type I interferon)|go:"GO:0045087"(innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|rcsb pdb:5JW7|reactome:R-HSA-3134975 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:SkaBrVIZl+9hhFmOaYAlmmudBFM11099 rogid:ezli6d8R3mc5aNovKvPv2ayypbE9606 intact-crc:D2828ED65E17C666|rigid:weNN7e1uIWb6ucMB0syUNP7IbiM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A9YDK9 uniprotkb:Q15370 intact:EBI-6152521 intact:EBI-301238|ensembl:ENSP00000386652|uniprotkb:B7WPD3 psi-mi:a9ydk9_bvdv(display_long)|uniprotkb:Npro(gene name)|psi-mi:Npro(display_short) psi-mi:elob_human(display_long)|uniprotkb:ELOB(gene name)|psi-mi:ELOB(display_short)|uniprotkb:Elongin 18 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit B(gene name synonym)|uniprotkb:SIII p18(gene name synonym)|uniprotkb:TCEB2(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11099(bvdv)|taxid:11099(Bovine viral diarrhea virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159292|imex:IM-17331-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|interpro:IPR042542|interpro:IPR008751(Peptidase C53, pestivirus Npro) ensembl:ENSG00000103363(gene)|ensembl:ENST00000409906(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039049|mint:Q15370|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2JZ3|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:4WQO|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:6SIS|refseq:NP_009039.1|refseq:NP_996896.1|dip:DIP-29570N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:SkaBrVIZl+9hhFmOaYAlmmudBFM11099 rogid:apX4QFpDC4Dz3MAs7tQ8+XFHx6I9606 intact-crc:D2828ED65E17C666|rigid:weNN7e1uIWb6ucMB0syUNP7IbiM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A9YDK9 uniprotkb:P22492 intact:EBI-6152521 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 psi-mi:a9ydk9_bvdv(display_long)|uniprotkb:Npro(gene name)|psi-mi:Npro(display_short) psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11099(bvdv)|taxid:11099(Bovine viral diarrhea virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159292|imex:IM-17331-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|interpro:IPR042542|interpro:IPR008751(Peptidase C53, pestivirus Npro) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:SkaBrVIZl+9hhFmOaYAlmmudBFM11099 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 intact-crc:D2828ED65E17C666|rigid:weNN7e1uIWb6ucMB0syUNP7IbiM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A9YDK9 uniprotkb:A7E2V4 intact:EBI-6152521 intact:EBI-947995|uniprotkb:Q17RS8|uniprotkb:Q2TAB8|uniprotkb:Q6P439|uniprotkb:Q8IW81|uniprotkb:Q8NB34|uniprotkb:Q9H8F3|uniprotkb:O94987|uniprotkb:B2RP37|ensembl:ENSP00000474748 psi-mi:a9ydk9_bvdv(display_long)|uniprotkb:Npro(gene name)|psi-mi:Npro(display_short) psi-mi:zswm8_human(display_long)|uniprotkb:ZSWIM8(gene name)|psi-mi:ZSWIM8(display_short)|uniprotkb:KIAA0913(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:11099(bvdv)|taxid:11099(Bovine viral diarrhea virus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159292|imex:IM-17331-61 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0019082"(viral protein processing)|go:"GO:0039548"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity)|interpro:IPR042542|interpro:IPR008751(Peptidase C53, pestivirus Npro) refseq:NP_001229416.1|refseq:NP_001229417.1|refseq:NP_055852.2|refseq:XP_006717788.1|ensembl:ENSG00000214655(gene)|ensembl:ENST00000605216(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1902667"(regulation of axon guidance)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|go:"GO:2000627"(positive regulation of miRNA catabolic process)|interpro:IPR007527(Zinc finger, SWIM-type)|reactome:R-HSA-9010553 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:SkaBrVIZl+9hhFmOaYAlmmudBFM11099 rogid:L/Zc7H24cEC7qtYp34nahN0pKEc9606 intact-crc:D2828ED65E17C666|rigid:weNN7e1uIWb6ucMB0syUNP7IbiM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04297 uniprotkb:P12036 intact:EBI-6152549|uniprotkb:Q85352 intact:EBI-2880271|uniprotkb:Q9UQ14|uniprotkb:Q9UJS7|uniprotkb:Q96HF8|uniprotkb:B4DYY4|ensembl:ENSP00000311997 psi-mi:k1_vaccw(display_long)|uniprotkb:32.5 kDa protein(gene name synonym)|uniprotkb:Host range protein 1(gene name synonym)|uniprotkb:K1L(orf name)|uniprotkb:VACWR032(locus name) psi-mi:nfh_human(display_long)|uniprotkb:NEFH(gene name)|psi-mi:NEFH(display_short)|uniprotkb:KIAA0845(gene name synonym)|uniprotkb:NFH(gene name synonym)|uniprotkb:200 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament triplet H protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159316|imex:IM-17331-62 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|interpro:IPR036770|interpro:IPR002110(Ankyrin)|interpro:IPR020683|refseq:YP_232914.1 refseq:NP_066554.2|ensembl:ENSG00000100285(gene)|ensembl:ENST00000310624(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005883"(neurofilament)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0061564"(axon development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR010790(Protein of unknown function DUF1388)|interpro:IPR018039|interpro:IPR033183|interpro:IPR039008|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:1AozC22mCzmE3PRH6okg7ifUoP810254 rogid:TXMrn6SWBHIYQY1loZfVvMo9PtU9606 intact-crc:30E50723F2FA9703|rigid:KFnRuHlomQ1wMu4jDlHh0KdVTlw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P04297 uniprotkb:Q15057 intact:EBI-6152549|uniprotkb:Q85352 intact:EBI-4401196|uniprotkb:A8K2V4|uniprotkb:Q8N5Z8|uniprotkb:Q9UQR3|ensembl:ENSP00000324287 psi-mi:k1_vaccw(display_long)|uniprotkb:32.5 kDa protein(gene name synonym)|uniprotkb:Host range protein 1(gene name synonym)|uniprotkb:K1L(orf name)|uniprotkb:VACWR032(locus name) psi-mi:acap2_human(display_long)|uniprotkb:ACAP2(gene name)|psi-mi:ACAP2(display_short)|uniprotkb:CENTB2(gene name synonym)|uniprotkb:KIAA0041(gene name synonym)|uniprotkb:Centaurin-beta-2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10254(vaccw)|taxid:10254("vaccinia virus (stra") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159316|imex:IM-17331-62 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039503"(suppression by virus of host innate immune response)|go:"GO:0039644"(suppression by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|interpro:IPR036770|interpro:IPR002110(Ankyrin)|interpro:IPR020683|refseq:YP_232914.1 refseq:NP_036419.3|ensembl:ENSG00000114331(gene)|ensembl:ENST00000326793(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030029"(actin filament-based process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0046872"(metal ion binding)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|rcsb pdb:6IF3 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:1AozC22mCzmE3PRH6okg7ifUoP810254 rogid:VHSpT12NSofZq3m02WlQNqj1IAQ9606 intact-crc:30E50723F2FA9703|rigid:KFnRuHlomQ1wMu4jDlHh0KdVTlw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:Q00839 intact:EBI-6152568 intact:EBI-351126|uniprotkb:O75507|uniprotkb:Q8N174|uniprotkb:Q96HY9|uniprotkb:Q9BQ09|ensembl:ENSP00000491215 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:hnrpu_human(display_long)|uniprotkb:HNRNPU(gene name)|psi-mi:HNRNPU(display_short)|uniprotkb:SAFA(gene name synonym)|uniprotkb:U21.1(gene name synonym)|uniprotkb:HNRPU(gene name synonym)|uniprotkb:p120(gene name synonym)|uniprotkb:pp120(gene name synonym)|uniprotkb:C1orf199(gene name synonym)|uniprotkb:GRIP120(gene name synonym)|uniprotkb:Nuclear p120 ribonucleoprotein(gene name synonym)|uniprotkb:Scaffold-attachment factor A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") refseq:NP_004492.2|refseq:NP_114032.2|ensembl:ENSG00000153187(gene)|ensembl:ENST00000640218(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:1990498"(mitotic spindle microtubule)|go:"GO:0098577"(inactive sex chromosome)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR026745|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q00839|rcsb pdb:1ZRJ|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990280"(RNA localization to chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006396"(RNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008143"("poly(A) binding")|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0017130"("poly(C) RNA binding")|go:"GO:0030496"(midbody)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|refseq:XP_016856604.1|refseq:XP_016856605.1|refseq:XP_016856606.1|dip:DIP-684N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:n73PY0Vis+D5Iq0q77h5Ck2V4789606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:P31942 intact:EBI-6152568 intact:EBI-711437|uniprotkb:Q9NPI4|uniprotkb:Q9UFU4|uniprotkb:Q9Y4J5|uniprotkb:Q9BSX1|uniprotkb:Q9NP53|uniprotkb:Q9NP96|uniprotkb:Q9NPA7|ensembl:ENSP00000265866|uniprotkb:A8K682|uniprotkb:B3KRE1 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:hnrh3_human(display_long)|uniprotkb:HNRNPH3(gene name)|psi-mi:HNRNPH3(display_short)|uniprotkb:HNRPH3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein 2H9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") ensembl:ENSG00000096746(gene)|ensembl:ENST00000265866(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034969|interpro:IPR034970|interpro:IPR035979|mint:P31942|refseq:NP_036339.1|refseq:NP_067676.2|refseq:NP_001309363.1|refseq:NP_001309365.1|refseq:NP_001309366.1|refseq:NP_001309367.1|refseq:NP_001309368.1|refseq:NP_001309369.1|refseq:NP_001309370.1|refseq:NP_001309374.1|refseq:NP_001309375.1|refseq:NP_001309376.1|refseq:NP_001309377.1|refseq:NP_001309378.1|refseq:XP_016871657.1|refseq:XP_016871658.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:iJGBIhPXnQIIFQmgxWB1WjwVXSY9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:P62269 intact:EBI-6152568 intact:EBI-352451|ensembl:ENSP00000211372|ensembl:ENSP00000393241|ensembl:ENSP00000403175|ensembl:ENSP00000412583|ensembl:ENSP00000416110|uniprotkb:P25232|uniprotkb:Q6IPF8|uniprotkb:Q5SUJ3 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:rs18_human(display_long)|uniprotkb:RPS18(gene name)|psi-mi:RPS18(display_short)|uniprotkb:D6S218E(gene name synonym)|uniprotkb:Ke-3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS13(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") refseq:NP_072045.1|ensembl:ENSG00000096150(gene)|ensembl:ENSG00000223367(gene)|ensembl:ENSG00000226225(gene)|ensembl:ENSG00000231500(gene)|ensembl:ENSG00000235650(gene)|ensembl:ENST00000211372(transcript)|ensembl:ENST00000434122(transcript)|ensembl:ENST00000439602(transcript)|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENST00000454021(transcript)|ensembl:ENST00000457341(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001892(Ribosomal protein S13)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR018269|interpro:IPR027437|mint:P62269|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|dip:DIP-32892N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:yOHgKM/BuvgGdqp1OEVPeuiABg89606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:Q86U42 intact:EBI-6152568 intact:EBI-1226435|uniprotkb:O43484|uniprotkb:D3DS49|ensembl:ENSP00000216727 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:pabp2_human(display_long)|uniprotkb:PABPN1(gene name)|psi-mi:PABPN1(display_short)|uniprotkb:PAB2(gene name synonym)|uniprotkb:PABP2(gene name synonym)|uniprotkb:"Poly(A)-binding protein II"(gene name synonym)|uniprotkb:Polyadenylate-binding nuclear protein 1(gene name synonym)|uniprotkb:"Nuclear poly(A)-binding protein 1"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") refseq:NP_004634.1|dip:DIP-37968N|go:"GO:0000165"(MAPK cascade)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|ensembl:ENSG00000100836(gene)|ensembl:ENST00000216727(transcript)|go:"GO:0006936"(muscle contraction)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1904247"(positive regulation of polynucleotide adenylyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034911|interpro:IPR035979|mint:Q86U42|rcsb pdb:3B4D|rcsb pdb:3B4M|rcsb pdb:3UCG|reactome:R-HSA-168315|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0070063"(RNA polymerase binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:NxWuFTvVqshfu+ZIsZMIZEdSk2k9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:Q99729 intact:EBI-6152568 intact:EBI-1044873|uniprotkb:Q04150|uniprotkb:Q8N7U3|uniprotkb:Q9BQ99|intact:EBI-2339961|uniprotkb:B3KNN5|uniprotkb:D3DWP7 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:roaa_human(display_long)|uniprotkb:HNRPAB(gene name synonym)|uniprotkb:APOBEC1-binding protein 1(gene name synonym)|uniprotkb:HNRNPAB(gene name)|psi-mi:HNRNPAB(display_short)|uniprotkb:ABBP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") refseq:NP_004490.2|refseq:NP_112556.2|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR034846|interpro:IPR035979|rcsb pdb:3S7R|mint:Q99729|dip:DIP-50394N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:NzusDKSvcoVb90LNvXpaMAvg0Oo9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:O43390 intact:EBI-6152568 intact:EBI-713419|uniprotkb:S4R3J4|uniprotkb:Q5TEH1|ensembl:ENSP00000304405|ensembl:ENSP00000363741|ensembl:ENSP00000489252|ensembl:ENSP00000489371|uniprotkb:Q9BV64|uniprotkb:Q2L7G6 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:hnrpr_human(display_long)|uniprotkb:HNRPR(gene name synonym)|uniprotkb:HNRNPR(gene name)|psi-mi:HNRNPR(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") refseq:NP_001095868.1|refseq:XP_005245768.1|ensembl:ENSG00000125944(gene)|ensembl:ENSG00000282958(gene)|ensembl:ENST00000302271(transcript)|ensembl:ENST00000374612(transcript)|ensembl:ENST00000634263(transcript)|ensembl:ENST00000634766(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043679"(axon terminus)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034411|interpro:IPR035979|mint:O43390|rcsb pdb:2DK2|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR041337|refseq:NP_005817.1|refseq:XP_011538773.1|refseq:NP_001284549.1|refseq:XP_016855497.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:UiOaRbnMd1S2FthR4RWltyq6xT49606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:Q9NZI8 intact:EBI-6152568 intact:EBI-1053892|uniprotkb:C9JT33|ensembl:ENSP00000290341 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:if2b1_human(display_long)|uniprotkb:ZBP1(gene name synonym)|uniprotkb:IGF-II mRNA-binding protein 1(gene name synonym)|uniprotkb:Coding region determinant-binding protein(gene name synonym)|uniprotkb:VICKZ family member 1(gene name synonym)|uniprotkb:IGF2BP1(gene name)|psi-mi:IGF2BP1(display_short)|uniprotkb:Zipcode-binding protein 1(gene name synonym)|uniprotkb:CRDBP(gene name synonym)|uniprotkb:VICKZ1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") refseq:NP_006537.3|refseq:NP_001153895.1|ensembl:ENSG00000159217(gene)|ensembl:ENST00000290341(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007399"(nervous system development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010610"(regulation of mRNA stability involved in response to stress)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022013"(pallium cell proliferation in forebrain)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0140059"(dendrite arborization)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034837|interpro:IPR034842|interpro:IPR035979|interpro:IPR036612|mint:Q9NZI8|rcsb pdb:3KRM|rcsb pdb:6QEY|reactome:R-HSA-428359|reactome:R-HSA-5687128|dip:DIP-38139N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:3Ps/PWWYr0WpYcx3G/AOiQEj+vc9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:P38159 intact:EBI-6152568 intact:EBI-743526|ensembl:ENSP00000359645|uniprotkb:Q5JQ67|uniprotkb:Q969R3|uniprotkb:D3DWH0|uniprotkb:E9PG86|uniprotkb:Q8N8Y7|uniprotkb:B4E3U4 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:rbmx_human(display_long)|uniprotkb:Glycoprotein p43(gene name synonym)|uniprotkb:RBMX(gene name)|psi-mi:RBMX(display_short)|uniprotkb:HNRPG(gene name synonym)|uniprotkb:RBMXP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") ensembl:ENSG00000147274(gene)|ensembl:ENST00000320676(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P38159|rcsb pdb:2MB0|rcsb pdb:2MKS|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_002130.2|refseq:NP_001158275.1|dip:DIP-34447N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:ocCkdy9PxjeVLUQf0tMVCEhFfO89606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:Q08211 intact:EBI-6152568 intact:EBI-352022|intact:EBI-1058470|uniprotkb:Q5VY62|uniprotkb:Q6PD69|uniprotkb:Q99556|uniprotkb:B2RNV4|uniprotkb:Q05CI5|uniprotkb:Q12803|uniprotkb:Q32Q22|ensembl:ENSP00000356520 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:dhx9_human(display_long)|uniprotkb:DHX9(gene name)|psi-mi:DHX9(display_short)|uniprotkb:DDX9(gene name synonym)|uniprotkb:NDH2(gene name synonym)|uniprotkb:DExH-box helicase 9(gene name synonym)|uniprotkb:RNA helicase A(gene name synonym)|uniprotkb:LKP(gene name synonym)|uniprotkb:Nuclear DNA helicase II(gene name synonym)|uniprotkb:DEAH box protein 9(gene name synonym)|uniprotkb:Leukophysin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") refseq:NP_001348.2|dip:DIP-31504N|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033679"(3'-5' DNA/RNA helicase activity)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045142"(triplex DNA binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0097165"(nuclear stress granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1905172"(RISC complex binding)|go:"GO:1905538"(polysome binding)|go:"GO:1905698"(positive regulation of polysome binding)|go:"GO:1990518"(single-stranded 3'-5' DNA helicase activity)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000765"(regulation of cytoplasmic translation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR044445|interpro:IPR044446|interpro:IPR044447|mint:Q08211|rcsb pdb:3LLM|rcsb pdb:3VYX|rcsb pdb:3VYY|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-72163|go:"GO:1904973"(positive regulation of viral translation)|ensembl:ENSG00000135829(gene)|ensembl:ENST00000367549(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006260"(DNA replication)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0016604"(nuclear body) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:b0VP2Frtvwa9WbYVMwB6TbV2uGU9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:O14654 intact:EBI-6152568 intact:EBI-356594|ensembl:ENSP00000505547 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:Q12905 intact:EBI-6152568 intact:EBI-357925|uniprotkb:A6NDB0|uniprotkb:Q5SR10|uniprotkb:Q5SR11|uniprotkb:Q7L7R3|uniprotkb:Q9BWD4|uniprotkb:Q9P1N0|uniprotkb:B2R8G7|ensembl:ENSP00000355011 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:ilf2_human(display_long)|uniprotkb:PRO3063(orf name)|uniprotkb:NF45(gene name synonym)|uniprotkb:ILF2(gene name)|psi-mi:ILF2(display_short)|uniprotkb:Nuclear factor of activated T-cells 45 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") refseq:NP_004506.2|refseq:NP_001254738.1|ensembl:ENSG00000143621(gene)|ensembl:ENST00000361891(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR043519|mint:Q12905|reactome:R-HSA-6798695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:HwUDuY6Ev7csoTThxZCW8nJT88o9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:P31943 intact:EBI-6152568 intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168|ensembl:ENSP00000377082|ensembl:ENSP00000397797|ensembl:ENSP00000492076|ensembl:ENSP00000495786 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") refseq:NP_005511.1|refseq:NP_001244222.1|ensembl:ENSG00000169045(gene)|ensembl:ENSG00000284254(gene)|ensembl:ENST00000356731(transcript)|ensembl:ENST00000393432(transcript)|ensembl:ENST00000442819(transcript)|ensembl:ENST00000638505(transcript)|ensembl:ENST00000643310(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:P14866 intact:EBI-6152568 intact:EBI-719024|uniprotkb:Q9H3P3|uniprotkb:A6ND69|uniprotkb:A6NIT8|ensembl:ENSP00000221419|ensembl:ENSP00000489021 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:hnrpl_human(display_long)|uniprotkb:HNRPL(gene name synonym)|uniprotkb:HNRNPL(gene name)|psi-mi:HNRNPL(display_short)|uniprotkb:P/OKcl.14(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") refseq:NP_001005335.1|refseq:NP_001524.2|refseq:XP_011525191.1|ensembl:ENSG00000282947(gene)|ensembl:ENST00000221419(transcript)|ensembl:ENST00000634753(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097157"(pre-mRNA intronic binding)|ensembl:ENSG00000104824(gene)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034816|interpro:IPR034817|interpro:IPR035005|interpro:IPR035008|interpro:IPR035979|mint:P14866|rcsb pdb:3R27|rcsb pdb:3TO8|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:1990904"(ribonucleoprotein complex)|dip:DIP-36355N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:vOfznm03e6Ottg6BptYHmR9qJEc9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:O00459 intact:EBI-6152568 intact:EBI-346930|uniprotkb:Q5EAT5|uniprotkb:Q9UPH9|intact:EBI-28974273|ensembl:ENSP00000222254 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:p85b_human(display_long)|uniprotkb:PIK3R2(gene name)|psi-mi:PIK3R2(display_short)|uniprotkb:Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") ensembl:ENSP00000222254|refseq:NP_005018.1|dip:DIP-31811N|ensembl:ENSG00000105647(gene)|ensembl:ENST00000222254(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015031"(protein transport)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043551"(regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|rcsb pdb:6OX7|rcsb pdb:6U28|reactome:R-HSA-109704|reactome:R-HSA-112399|reactome:R-HSA-114604|reactome:R-HSA-1257604|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1660499|reactome:R-HSA-186763|reactome:R-HSA-198203|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035586|interpro:IPR036028|interpro:IPR036860|mint:O00459|rcsb pdb:2KT1|rcsb pdb:2XS6|rcsb pdb:3MTT|rcsb pdb:3O5Z|reactome:R-HSA-202424|reactome:R-HSA-2029485|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-388841|reactome:R-HSA-389357|reactome:R-HSA-416476|reactome:R-HSA-4420097|reactome:R-HSA-512988|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8853659|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-210993|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-912526|reactome:R-HSA-912631|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|reactome:R-HSA-9013409 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:Ij0WS0eKPwShgFWQc7OEss7AcAU9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:Q08380 intact:EBI-6152568 intact:EBI-354956|ensembl:ENSP00000262776|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") ensembl:ENSG00000108679(gene)|ensembl:ENST00000262776(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017448(Speract/scavenger receptor related)|go:"GO:0007155"(cell adhesion)|interpro:IPR036772|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|refseq:NP_005558.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:P16989 intact:EBI-6152568 intact:EBI-358193|uniprotkb:Q14121|uniprotkb:Q969N6|uniprotkb:Q96B76|uniprotkb:B2RBW6|intact:EBI-2560381|ensembl:ENSP00000228251 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:ybox3_human(display_long)|uniprotkb:YBX3(gene name)|psi-mi:YBX3(display_short)|uniprotkb:CSDA(gene name synonym)|uniprotkb:Cold shock domain-containing protein A(gene name synonym)|uniprotkb:DBPA(gene name synonym)|uniprotkb:DNA-binding protein A(gene name synonym)|uniprotkb:Single-strand DNA-binding protein NF-GMB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") go:"GO:0046622"(positive regulation of organ growth)|refseq:NP_001138898.1|refseq:NP_003642.3|dip:DIP-42489N|ensembl:ENSG00000060138(gene)|ensembl:ENST00000228251(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008584"(male gonad development)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031267"(small GTPase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:1902219"(negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1905538"(polysome binding)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P16989 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:cWuhmwOBWe5HdgPG1gyN7KzN4Rs9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:Q13310 intact:EBI-6152568 intact:EBI-372844|uniprotkb:Q6P0N3|uniprotkb:B1ANQ8|ensembl:ENSP00000361948|intact:EBI-877641|uniprotkb:Q4VC03 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:pabp4_human(display_long)|uniprotkb:PABPC4(gene name)|psi-mi:PABPC4(display_short)|uniprotkb:APP1(gene name synonym)|uniprotkb:PABP4(gene name synonym)|uniprotkb:"Inducible poly(A)-binding protein"(gene name synonym)|uniprotkb:Activated-platelet protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") refseq:NP_001129126.1|refseq:NP_003810.1|ensembl:ENSG00000090621(gene)|ensembl:ENST00000372857(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006412"(translation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0061515"(myeloid cell development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:Q13310|refseq:NP_001129125.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:u1qCM3o5X7jLIa1vyqFCIH7v01w9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:Q9BUJ2 intact:EBI-6152568 intact:EBI-1018153|uniprotkb:O76022|uniprotkb:Q6ZSZ0|uniprotkb:Q7L8P4|uniprotkb:Q8N6Z4|uniprotkb:Q96G37|uniprotkb:Q9HAL3|uniprotkb:Q9UG75|intact:EBI-3183399|intact:EBI-2339292|uniprotkb:B3KMW7|ensembl:ENSP00000375863|intact:EBI-2563529 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:hnrl1_human(display_long)|uniprotkb:E1BAP5(gene name synonym)|uniprotkb:HNRNPUL1(gene name)|psi-mi:HNRNPUL1(display_short)|uniprotkb:HNRPUL1(gene name synonym)|uniprotkb:Adenovirus early region 1B-associated protein 5(gene name synonym)|uniprotkb:E1B-55 kDa-associated protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") refseq:NP_008971.2|refseq:NP_653333.1|go:"GO:0009615"(response to virus)|go:"GO:0019899"(enzyme binding)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027025|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q9BUJ2|reactome:R-HSA-72163|ensembl:ENSG00000105323(gene)|ensembl:ENST00000392006(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|refseq:NP_001308140.1|refseq:NP_001308137.1|dip:DIP-39419N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:IahA7SVR1NmvldrWKQlAwApinQE9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:Q9HAV7 intact:EBI-6152568 intact:EBI-1043499|uniprotkb:Q549M6|uniprotkb:B2R783|ensembl:ENSP00000264954 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:grpe1_human(display_long)|uniprotkb:Mt-GrpE#1(gene name synonym)|uniprotkb:HMGE(gene name synonym)|uniprotkb:GRPEL1(gene name)|psi-mi:GRPEL1(display_short)|uniprotkb:GREPEL1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") ensembl:ENSG00000109519(gene)|ensembl:ENST00000264954(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001405"(PAM complex, Tim23 associated import motor)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR000740(GrpE nucleotide exchange factor)|interpro:IPR009012(GrpE nucleotide exchange factor, head)|interpro:IPR013805(GrpE nucleotide exchange factor, coiled-coil)|mint:Q9HAV7|reactome:R-HSA-1268020|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_079472.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:OWuX4gnZBzxgv0arSEKY9KyZZ+o9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:Q8N163 intact:EBI-6152568 intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|ensembl:ENSP00000310670|ensembl:ENSP00000373930|uniprotkb:B2RB79|uniprotkb:D3DSR6 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") refseq:NP_066997.3|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|interpro:IPR028811|mint:Q8N163|reactome:R-HSA-3371453|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|dip:DIP-38122N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:P62829 intact:EBI-6152568 intact:EBI-353303|uniprotkb:P23131|uniprotkb:Q3SWV7|uniprotkb:P24048|uniprotkb:Q29246|uniprotkb:Q6P5S1|ensembl:ENSP00000377865|ensembl:ENSP00000420311 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:rl23_human(display_long)|uniprotkb:RPL23(gene name)|psi-mi:RPL23(display_short)|uniprotkb:60S ribosomal protein L17(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|reactome:R-HSA-9010553|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|refseq:NP_000969.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000218(Ribosomal protein L14b/L23e)|interpro:IPR019972|interpro:IPR036853|mint:P62829|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|ensembl:ENSG00000125691(gene)|ensembl:ENST00000394332(transcript)|ensembl:ENST00000479035(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0005730"(nucleolus)|dip:DIP-33156N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:TiSVU2W4+lkwf12eb4+vG6IFlZA9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:P35268 intact:EBI-6152568 intact:EBI-354533|intact:EBI-1055963|uniprotkb:Q6IBD1|uniprotkb:B2R495|ensembl:ENSP00000346088 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:rl22_human(display_long)|uniprotkb:RPL22(gene name)|psi-mi:RPL22(display_short)|uniprotkb:Heparin-binding protein HBp15(gene name synonym)|uniprotkb:Epstein-Barr virus small RNA-associated protein(gene name synonym)|uniprotkb:EBER-associated protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL22(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") refseq:NP_000974.1|ensembl:ENSG00000116251(gene)|ensembl:ENST00000234875(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008201"(heparin binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0045182"(translation regulator activity)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099577"(regulation of translation at presynapse, modulating synaptic transmission)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002671(Ribosomal protein L22e)|interpro:IPR038526|mint:P35268|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|reactome:R-HSA-72706|rcsb pdb:6Z6L|rcsb pdb:6Z6M|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:0TVillnqDkHmdTwxIedAJCVAdzY9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:P07437 intact:EBI-6152568 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:P63267 intact:EBI-6152568 intact:EBI-297795|uniprotkb:P12718|uniprotkb:Q504R1|uniprotkb:Q6FI22|ensembl:ENSP00000295137|ensembl:ENSP00000386857|uniprotkb:B2R7E7|uniprotkb:D6W5H8|uniprotkb:B4E315|uniprotkb:E9PG30 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:acth_human(display_long)|uniprotkb:ACTG2(gene name)|psi-mi:ACTG2(display_short)|uniprotkb:ACTA3(gene name synonym)|uniprotkb:ACTSG(gene name synonym)|uniprotkb:Smooth muscle gamma-actin(gene name synonym)|uniprotkb:Gamma-2-actin(gene name synonym)|uniprotkb:Alpha-actin-3(gene name synonym)|uniprotkb:ACTL3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0032982"(myosin filament)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:6JAT|reactome:R-HSA-445355|go:"GO:0010628"(positive regulation of gene expression)|ensembl:ENST00000345517(transcript)|ensembl:ENST00000409624(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|ensembl:ENSG00000163017(gene)|refseq:NP_001186822.1|refseq:NP_001606.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:tp0JsXhrGsRl5i4Wg2dyaPGUPxA9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:P23396 intact:EBI-6152568 intact:EBI-351193|uniprotkb:Q498B5|uniprotkb:Q8NI95|uniprotkb:B2R7N5|ensembl:ENSP00000433821|ensembl:ENSP00000434643|ensembl:ENSP00000436971|uniprotkb:J3KN86 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:rs3_human(display_long)|uniprotkb:RPS3(gene name)|psi-mi:RPS3(display_short)|uniprotkb:Small ribosomal subunit protein uS3(gene name synonym)|uniprotkb:OK/SW-cl.26(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") refseq:NP_000996.2|ensembl:ENSG00000149273(gene)|ensembl:ENST00000524851(transcript)|ensembl:ENST00000527446(transcript)|ensembl:ENST00000531188(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR004044(K Homology, type 2)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|go:"GO:0071159"(NF-kappaB complex)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR018280|interpro:IPR036419|mint:P23396|rcsb pdb:1WH9|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|rcsb pdb:6QZP|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|refseq:NP_001243731.1|refseq:NP_001247436.1|refseq:NP_001247435.1|dip:DIP-33177N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:fsDW18AMR3YyEEIhMVcngYRWkps9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:P51991 intact:EBI-6152568 intact:EBI-1050760|uniprotkb:Q53RW7|uniprotkb:Q6URK5|uniprotkb:D3DPF4|ensembl:ENSP00000376309|ensembl:ENSP00000416340|ensembl:ENSP00000503593|ensembl:ENSP00000504135|ensembl:ENSP00000504152 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:roa3_human(display_long)|uniprotkb:HNRPA3(gene name synonym)|uniprotkb:HNRNPA3(gene name)|psi-mi:HNRNPA3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") refseq:NP_919223.1|refseq:NP_001317178.1|ensembl:ENSG00000170144(gene)|ensembl:ENST00000392524(transcript)|ensembl:ENST00000435711(transcript)|ensembl:ENST00000676629(transcript)|ensembl:ENST00000678111(transcript)|ensembl:ENST00000679159(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0051028"(mRNA transport)|go:"GO:0051033"(RNA transmembrane transporter activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034513|interpro:IPR034516|interpro:IPR035979|mint:P51991|reactome:R-HSA-72163|reactome:R-HSA-72203 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:bbg0nIdhEHomcwtgZhT2yHy7+nU9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:Q12906 intact:EBI-6152568 intact:EBI-78756|uniprotkb:A8K6F2|uniprotkb:O43409|uniprotkb:Q6P1X1|uniprotkb:Q86XY7|uniprotkb:Q99544|uniprotkb:Q99545|uniprotkb:Q9BZH4|uniprotkb:Q9BZH5|uniprotkb:Q9NQ95|uniprotkb:Q9NQ96|uniprotkb:Q9NQ97|uniprotkb:Q9NQ98|uniprotkb:Q9NQ99|uniprotkb:Q9NQA0|uniprotkb:Q9NQA1|uniprotkb:Q9NQA2|uniprotkb:Q9NRN2|uniprotkb:Q9NRN3|uniprotkb:Q9NRN4|uniprotkb:Q9UMZ9|uniprotkb:Q9UN00|uniprotkb:Q9UN84|uniprotkb:Q9UNA2|ensembl:ENSP00000468156|intact:EBI-10970055|uniprotkb:G5E9M5 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:ilf3_human(display_long)|uniprotkb:ILF3(gene name)|psi-mi:ILF3(display_short)|uniprotkb:MPHOSPH4(gene name synonym)|uniprotkb:NF90(gene name synonym)|uniprotkb:Nuclear factor of activated T-cells 90 kDa(gene name synonym)|uniprotkb:Double-stranded RNA-binding protein 76(gene name synonym)|uniprotkb:Translational control protein 80(gene name synonym)|uniprotkb:Nuclear factor associated with dsRNA(gene name synonym)|uniprotkb:M-phase phosphoprotein 4(gene name synonym)|uniprotkb:DRBF(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") ensembl:ENSG00000129351(gene)|ensembl:ENST00000590261(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051607"(defense response to virus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR033099|interpro:IPR043519|mint:Q12906|rcsb pdb:2L33|rcsb pdb:3P1X|refseq:NP_001131145.1|refseq:NP_004507.2|refseq:NP_036350.2|refseq:NP_060090.2|refseq:NP_703194.1|refseq:XP_016882252.1|refseq:XP_011526286.2|dip:DIP-29853N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:iri+WBUtektANRSCpBO1XBCd9Wk9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:P09651 intact:EBI-6152568 intact:EBI-352662|uniprotkb:Q3MIB7|uniprotkb:Q6PJZ7|ensembl:ENSP00000341826|ensembl:ENSP00000503610|uniprotkb:A8K4Z8|intact:EBI-2556572 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:roa1_human(display_long)|uniprotkb:HNRNPA1(gene name)|psi-mi:HNRNPA1(display_short)|uniprotkb:HNRPA1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:Single-strand RNA-binding protein(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") refseq:NP_002127.1|refseq:NP_112420.1|ensembl:ENSG00000135486(gene)|ensembl:ENST00000340913(transcript)|ensembl:ENST00000677210(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|rcsb pdb:2LYV|rcsb pdb:2UP1|rcsb pdb:4YOE|rcsb pdb:5MPG|rcsb pdb:5MPL|rcsb pdb:5ZGD|rcsb pdb:5ZGL|rcsb pdb:6BXX|rcsb pdb:6DCL|rcsb pdb:6J60|rcsb pdb:7BX7|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035198"(miRNA binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051170"(import into nucleus)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR034845|interpro:IPR035979|mint:P09651|rcsb pdb:1HA1|rcsb pdb:1L3K|rcsb pdb:1PGZ|rcsb pdb:1PO6|rcsb pdb:1U1K|rcsb pdb:1U1L|rcsb pdb:1U1M|rcsb pdb:1U1N|rcsb pdb:1U1O|rcsb pdb:1U1P|rcsb pdb:1U1Q|rcsb pdb:1U1R|rcsb pdb:1UP1|rcsb pdb:2H4M|refseq:XP_005268883.1|dip:DIP-29338N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:ECXjsLRVtNc/aOw90tEFxowHc6c9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:Q9HCE1 intact:EBI-6152568 intact:EBI-1055820|uniprotkb:Q5JR03|uniprotkb:Q8TEF0|uniprotkb:Q9BSY3|uniprotkb:Q9BUJ9|ensembl:ENSP00000350028|ensembl:ENSP00000358659|ensembl:ENSP00000399797 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:mov10_human(display_long)|uniprotkb:Moloney leukemia virus 10 protein(gene name synonym)|uniprotkb:MOV10(gene name)|psi-mi:MOV10(display_short)|uniprotkb:KIAA1631(gene name synonym)|uniprotkb:Armitage homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") refseq:NP_001273001.1|refseq:NP_001123551.1|refseq:NP_066014.1|refseq:NP_001308253.1|ensembl:ENSG00000155363(gene)|ensembl:ENST00000357443(transcript)|ensembl:ENST00000369645(transcript)|ensembl:ENST00000413052(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010526"(negative regulation of transposition, RNA-mediated)|go:"GO:0032574"(5'-3' RNA helicase activity)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043186"(P granule)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR026122|interpro:IPR027417|interpro:IPR041679|mint:Q9HCE1|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-4086398|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8853884|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-8936459|dip:DIP-44158N|refseq:XP_005270926.1|refseq:XP_005270927.1|refseq:XP_016856807.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:symbA7qOGiAY2NuQXO+5gv/It3k9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:P43243 intact:EBI-6152568 intact:EBI-352602|ensembl:ENSP00000378284|ensembl:ENSP00000482895|uniprotkb:Q9UHW0|uniprotkb:Q9UQ27|uniprotkb:D3DQC3|uniprotkb:B7ZAV5 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:matr3_human(display_long)|uniprotkb:KIAA0723(gene name synonym)|uniprotkb:MATR3(gene name)|psi-mi:MATR3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") ensembl:ENSG00000015479(gene)|ensembl:ENST00000394805(transcript)|ensembl:ENST00000618441(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:P43243|refseq:NP_001181883.1|refseq:NP_001181884.1|refseq:NP_061322.2|refseq:NP_954659.1|refseq:NP_001181885.1|refseq:NP_001269207.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:3UZlyCZHgdr1SBgUctv9Ev7XBSQ9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:Q13151 intact:EBI-6152568 intact:EBI-724092|ensembl:ENSP00000316042|intact:EBI-1043661|uniprotkb:Q6IB18 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:roa0_human(display_long)|uniprotkb:HNRPA0(gene name synonym)|uniprotkb:HNRNPA0(gene name)|psi-mi:HNRNPA0(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") refseq:NP_006796.1|ensembl:ENSG00000177733(gene)|ensembl:ENST00000314940(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006954"(inflammatory response)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034801|interpro:IPR035979|mint:Q13151|reactome:R-HSA-72163|reactome:R-HSA-72203 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:buyQxR8FLxd4N6jRhwVsroeGrBw9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:P62736 intact:EBI-6152568 intact:EBI-698810|uniprotkb:P03996|uniprotkb:P04108|uniprotkb:Q6FI19|uniprotkb:B2R8A4|ensembl:ENSP00000224784 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:acta_human(display_long)|uniprotkb:Alpha-actin-2(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 46 protein(gene name synonym)|uniprotkb:ACTA2(gene name)|psi-mi:ACTA2(display_short)|uniprotkb:ACTSA(gene name synonym)|uniprotkb:ACTVS(gene name synonym)|uniprotkb:GIG46(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") refseq:NP_001135417.1|refseq:NP_001604.1|refseq:NP_001307784.1|ensembl:ENSG00000107796(gene)|ensembl:ENST00000224784(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014829"(vascular associated smooth muscle contraction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072144"(glomerular mesangial cell development)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P62736|reactome:R-HSA-445355|reactome:R-HSA-9013695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:mRZGUdL/jBuj6nVHtxoasZuA7yA9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:P22626 intact:EBI-6152568 intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:O14979 intact:EBI-6152568 intact:EBI-299727|ensembl:ENSP00000295470|ensembl:ENSP00000422040|ensembl:ENSP00000483254|uniprotkb:Q6SPF2|uniprotkb:Q7KZ74|uniprotkb:Q7KZ75|uniprotkb:Q96IM0|uniprotkb:Q96S43 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:hnrdl_human(display_long)|uniprotkb:HNRNPDL(gene name)|psi-mi:HNRNPDL(display_short)|uniprotkb:AU-rich element RNA-binding factor(gene name synonym)|uniprotkb:HNRPDL(gene name synonym)|uniprotkb:JKT41-binding protein(gene name synonym)|uniprotkb:JKTBP(gene name synonym)|uniprotkb:Protein laAUF1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") ensembl:ENSG00000152795(gene)|ensembl:ENST00000295470(transcript)|ensembl:ENST00000502762(transcript)|ensembl:ENST00000621267(transcript)|go:"GO:0003677"(DNA binding)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034847|interpro:IPR035979|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|mint:O14979|go:"GO:0003723"(RNA binding)|reactome:R-HSA-8950505|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034046"("poly(G) binding")|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001193929.1|refseq:NP_112740.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:oOnEEar8AtKO5G6ldehucaRr4kM9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:Q9Y224 intact:EBI-6152568 intact:EBI-1104547|ensembl:ENSP00000261700 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:rtraf_human(display_long)|uniprotkb:RTRAF(gene name)|psi-mi:RTRAF(display_short)|uniprotkb:C14orf166(gene name synonym)|uniprotkb:CLE7 homolog(gene name synonym)|uniprotkb:CGI-99(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") refseq:NP_057123.1|ensembl:ENSG00000087302(gene)|ensembl:ENST00000261700(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050658"(RNA transport)|go:"GO:0072669"(tRNA-splicing ligase complex)|go:"GO:0072686"(mitotic spindle)|interpro:IPR019265|mint:Q9Y224|reactome:R-HSA-6784531 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:KRP0BO8XmEAtBag6wdctMHgVaEI9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:P67809 intact:EBI-6152568 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:Q15717 intact:EBI-6152568 intact:EBI-374260|uniprotkb:Q9BTT1|ensembl:ENSP00000385269|ensembl:ENSP00000472197|intact:EBI-6190219|uniprotkb:B4DVB8|uniprotkb:Q53XN6 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:elav1_human(display_long)|uniprotkb:ELAVL1(gene name)|psi-mi:ELAVL1(display_short)|uniprotkb:HUR(gene name synonym)|uniprotkb:Hu-antigen R(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") go:"GO:0006606"(protein import into nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035198"(miRNA binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|ensembl:ENSG00000066044(gene)|ensembl:ENST00000407627(transcript)|ensembl:ENST00000596459(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|refseq:NP_001410.2|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR034996|interpro:IPR035979|mint:Q15717|rcsb pdb:3HI9|rcsb pdb:4ED5|rcsb pdb:4EGL|rcsb pdb:4FXV|rcsb pdb:5SZW|rcsb pdb:6G2K|rcsb pdb:6GC5|rcsb pdb:6GD1|rcsb pdb:6GD2|rcsb pdb:6GD3|reactome:R-HSA-450520|reactome:R-HSA-72163|dip:DIP-31291N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:PciL5KuvP+2aUUv9cv7gWScgbw89606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:P07910 intact:EBI-6152568 intact:EBI-357966|uniprotkb:P22628|uniprotkb:Q53EX2|uniprotkb:Q59FD3|uniprotkb:Q5FWE8|uniprotkb:Q86SF8|uniprotkb:Q86U45|uniprotkb:Q96HK7|uniprotkb:Q96HM4|uniprotkb:Q96IY5|uniprotkb:Q9BTS3|uniprotkb:D3DS19|uniprotkb:D3DS22|intact:EBI-28976506|ensembl:ENSP00000404848|ensembl:ENSP00000451291|ensembl:ENSP00000452276 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:hnrpc_human(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") refseq:NP_001070910.1|refseq:NP_001070911.1|refseq:NP_004491.2|refseq:NP_112604.2|ensembl:ENSP00000404848|ensembl:ENST00000430246|ensembl:ENSP00000442816|ensembl:ENST00000553300|ensembl:ENSP00000450544|ensembl:ENSP00000451291|ensembl:ENST00000554969|ensembl:ENSP00000452276|ensembl:ENSP00000450725|ensembl:ENST00000555883|ensembl:ENSP00000450629|ensembl:ENST00000556628|ensembl:ENSP00000451652|ensembl:ENST00000556897|ensembl:ENSP00000451176|refseq:XP_011535010.1|refseq:XP_011535011.1|refseq:XP_011535012.1|refseq:XP_011535013.1|refseq:XP_011535014.1|refseq:XP_016876741.1|refseq:XP_016876742.1|dip:DIP-29854N|refseq:XP_006720188.1|ensembl:ENSG00000092199(gene)|ensembl:ENST00000420743(transcript)|ensembl:ENST00000554455(transcript)|ensembl:ENST00000557201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979|mint:P07910|rcsb pdb:1TXP|rcsb pdb:1WF2|rcsb pdb:2MXY|rcsb pdb:2MZ1|rcsb pdb:3LN4|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:Fj5tiH0wrNUjTnsURIg8dB8laMg9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:P61978 intact:EBI-6152568 intact:EBI-304185|intact:EBI-28971491|ensembl:ENSP00000317788|ensembl:ENSP00000353552|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q59F98|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62|uniprotkb:Q5T6W4|intact:EBI-3440248|uniprotkb:Q6IBN1 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:hnrpk_human(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") ensembl:ENSG00000165119(gene)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000351839(transcript)|ensembl:ENST00000360384(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0002102"(podosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61978|rcsb pdb:1J5K|rcsb pdb:1KHM|rcsb pdb:1ZZI|rcsb pdb:1ZZJ|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9610379|rcsb pdb:1ZZK|refseq:NP_002131.2|refseq:NP_112552.1|refseq:NP_112553.1|ensembl:ENSP00000317788|ensembl:ENSP00000353552|ensembl:ENST00000376263|ensembl:ENSP00000365439|ensembl:ENST00000376281|ensembl:ENSP00000365458|refseq:NP_001305115.1|refseq:NP_001305116.1|refseq:NP_001305117.1|refseq:XP_016870157.1|refseq:XP_005252017.1|refseq:XP_005252020.1|refseq:XP_005252022.1|dip:DIP-31805N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:P52597 intact:EBI-6152568 intact:EBI-352986|ensembl:ENSP00000338477|ensembl:ENSP00000349573|ensembl:ENSP00000400433|ensembl:ENSP00000438061|ensembl:ENSP00000507787|ensembl:ENSP00000348345|uniprotkb:Q5T0N2|uniprotkb:Q96AU2|uniprotkb:B3KM84 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:hnrpf_human(display_long)|uniprotkb:HNRNPF(gene name)|psi-mi:HNRNPF(display_short)|uniprotkb:HNRPF(gene name synonym)|uniprotkb:Nucleolin-like protein mcs94-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P52597|rcsb pdb:2HGL|rcsb pdb:2HGM|rcsb pdb:2HGN|rcsb pdb:2KFY|rcsb pdb:2KG0|rcsb pdb:2KG1|rcsb pdb:3TFY|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensembl:ENSG00000169813(gene)|ensembl:ENST00000337970(transcript)|ensembl:ENST00000356053(transcript)|ensembl:ENST00000357065(transcript)|ensembl:ENST00000443950(transcript)|ensembl:ENST00000544000(transcript)|ensembl:ENST00000682386(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001091674.1|refseq:NP_001091675.1|refseq:NP_001091676.1|refseq:NP_001091677.1|refseq:NP_001091678.1|refseq:NP_004957.1|dip:DIP-33145N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:pblzpldZOa5vlZ+zGQY9qyWCxaw9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:P11940 intact:EBI-6152568 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:D1LN35 uniprotkb:P25398 intact:EBI-6152568 intact:EBI-354542|uniprotkb:Q76M58|ensembl:ENSP00000230050 psi-mi:d1ln35_9infa(display_long)|uniprotkb:NS1(gene name)|psi-mi:NS1(display_short)|uniprotkb:NS(gene name synonym) psi-mi:rs12_human(display_long)|uniprotkb:RPS12(gene name)|psi-mi:RPS12(display_short)|uniprotkb:Small ribosomal subunit protein eS12(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:680716(h5n1-china)|taxid:680716("Influenza A virus (A/chicken/China/27402/1997(H5N1))") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159328|imex:IM-17331-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039524"(suppression by virus of host mRNA processing)|go:"GO:0039540"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000256("Influenza non-structural protein (NS1)")|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR038064|interpro:IPR004208("Influenza B non-structural protein (NS1)") refseq:NP_001007.2|ensembl:ENSG00000112306(gene)|ensembl:ENST00000230050(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR000530(Ribosomal protein S12e)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR029064|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72702|reactome:R-HSA-72695|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:sX67gSsEDhbRvmPeuYMG0A7xadk680716 rogid:80AIouzSdCvnLUSA7qsMp6naZ3g9606 intact-crc:40F1E509E92FEB30|rigid:4SgPZGpTU7aRXZx5cEF0kwlKIn4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P09012 intact:EBI-6152703 intact:EBI-607085|ensembl:ENSP00000243563 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:snrpa_human(display_long)|uniprotkb:SNRPA(gene name)|psi-mi:SNRPA(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005685"(U1 snRNP)|go:"GO:0030619"(U1 snRNA binding)|ensembl:ENSG00000077312(gene)|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034407|interpro:IPR034409|interpro:IPR035979|mint:P09012|rcsb pdb:1AUD|ensembl:ENST00000243563(transcript)|rcsb pdb:1DRZ|rcsb pdb:1DZ5|rcsb pdb:1FHT|rcsb pdb:1M5K|rcsb pdb:1M5O|rcsb pdb:1M5P|rcsb pdb:1M5V|rcsb pdb:1NU4|rcsb pdb:1OIA|rcsb pdb:1SJ3|rcsb pdb:1SJ4|rcsb pdb:1SJF|rcsb pdb:1U6B|rcsb pdb:1URN|rcsb pdb:1VBX|rcsb pdb:1VBY|rcsb pdb:1VBZ|rcsb pdb:1VC0|rcsb pdb:1VC5|rcsb pdb:1VC6|rcsb pdb:1ZZN|rcsb pdb:2A3J|rcsb pdb:2NZ4|rcsb pdb:2OIH|rcsb pdb:2OJ3|rcsb pdb:2U1A|rcsb pdb:3BO2|rcsb pdb:3BO3|rcsb pdb:3BO4|rcsb pdb:3CUL|rcsb pdb:3CUN|rcsb pdb:3EGZ|rcsb pdb:3G8S|rcsb pdb:3G8T|rcsb pdb:3G96|rcsb pdb:3G9C|rcsb pdb:3HHN|rcsb pdb:3IIN|rcsb pdb:3IRW|rcsb pdb:3IWN|rcsb pdb:3K0J|rcsb pdb:3L3C|rcsb pdb:3MUM|rcsb pdb:3MUR|rcsb pdb:3MUT|rcsb pdb:3R1H|rcsb pdb:3R1L|rcsb pdb:3UCU|rcsb pdb:3UCZ|rcsb pdb:3UD3|rcsb pdb:3UD4|rcsb pdb:3MUV|rcsb pdb:3UTR|rcsb pdb:4C4W|rcsb pdb:4PR6|rcsb pdb:4PRF|rcsb pdb:4W90|rcsb pdb:4W92|rcsb pdb:3MXH|rcsb pdb:3P49|rcsb pdb:3PGW|rcsb pdb:4YB1|rcsb pdb:5DDO|rcsb pdb:5DDP|rcsb pdb:5DDQ|rcsb pdb:5DDR|rcsb pdb:5FJ4|rcsb pdb:6LAS|rcsb pdb:6LAU|rcsb pdb:6LAX|rcsb pdb:6LAZ|rcsb pdb:6QX9|rcsb pdb:6SQN|rcsb pdb:6SQQ|rcsb pdb:6SQT|rcsb pdb:6SQV|rcsb pdb:6SR7|rcsb pdb:6XH0|rcsb pdb:6XH1|rcsb pdb:6XH2|rcsb pdb:6XH3|rcsb pdb:7AEP|rcsb pdb:7B0Y|rcsb pdb:7D7V|rcsb pdb:7LHX|reactome:R-HSA-72163|refseq:NP_004587.1|dip:DIP-29407N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:BJ9zdDzOPs9JYgU8lErj/maq0AY9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q8WXF1 intact:EBI-6152703 intact:EBI-1392258|uniprotkb:Q5JTQ3|uniprotkb:Q8NCZ9|uniprotkb:Q8WXE8|uniprotkb:Q9NV36|ensembl:ENSP00000343966|ensembl:ENSP00000481916 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:pspc1_human(display_long)|uniprotkb:PSPC1(gene name)|psi-mi:PSPC1(display_short)|uniprotkb:PSP1(gene name synonym)|uniprotkb:Paraspeckle protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:XP_006719907.1|refseq:NP_001035879.1|dip:DIP-39028N|refseq:XP_016876139.1|ensembl:ENSG00000121390(gene)|ensembl:ENST00000338910(transcript)|ensembl:ENST00000619300(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034522|interpro:IPR034523|interpro:IPR035979|mint:Q8WXF1|rcsb pdb:3SDE|rcsb pdb:5IFN|rcsb pdb:5WPA - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:voQ5zJMl7FYato9iDkUYfzZ3q/k9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P07437 intact:EBI-6152703 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P49736 intact:EBI-6152703 intact:EBI-374819|uniprotkb:Q14577|uniprotkb:Q15023|uniprotkb:Q8N2V1|uniprotkb:Q969W7|uniprotkb:Q96AE1|uniprotkb:Q9BRM7|ensembl:ENSP00000265056 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:mcm2_human(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:BM28(gene name synonym)|uniprotkb:CDCL1(gene name synonym)|uniprotkb:KIAA0030(gene name synonym)|uniprotkb:Minichromosome maintenance protein 2 homolog(gene name synonym)|uniprotkb:Nuclear protein BM28(gene name synonym)|uniprotkb:CCNL1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 ensembl:ENSG00000073111(gene)|ensembl:ENST00000265056(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006915"(apoptotic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090102"(cochlea development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P49736|rcsb pdb:4UUZ|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5JA4|rcsb pdb:6XTX|rcsb pdb:6XTY|rcsb pdb:6YA7|rcsb pdb:7CIZ|rcsb pdb:7CJ0|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|refseq:NP_004517.2|dip:DIP-31732N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:Jt9ODNyJBwtwQ0pb/+X46vtHfE09606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P34932 intact:EBI-6152703 intact:EBI-356933|uniprotkb:O95756|uniprotkb:Q2TAL4|uniprotkb:Q9BUK9|ensembl:ENSP00000302961 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:hsp74_human(display_long)|uniprotkb:HSPA4(gene name)|psi-mi:HSPA4(display_short)|uniprotkb:APG2(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-2(gene name synonym)|uniprotkb:HSP70RY(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_002145.3|dip:DIP-460N|ensembl:ENSG00000170606(gene)|ensembl:ENST00000304858(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042052|interpro:IPR043129|mint:P34932|reactome:R-HSA-3371453 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:4OkTlG9p3IQQBYloiuHS8+t13TM9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q06830 intact:EBI-6152703 intact:EBI-353193|ensembl:ENSP00000262746|ensembl:ENSP00000361152|ensembl:ENSP00000389047|ensembl:ENSP00000407034|ensembl:ENSP00000503140|uniprotkb:P35703|uniprotkb:Q2V576|uniprotkb:Q5T154|uniprotkb:Q5T155|uniprotkb:B5BU26|uniprotkb:D3DPZ8 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:prdx1_human(display_long)|uniprotkb:PRDX1(gene name)|psi-mi:PRDX1(display_short)|uniprotkb:PAGA(gene name synonym)|uniprotkb:PAGB(gene name synonym)|uniprotkb:TDPX2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Proliferation-associated gene protein(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor A(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 ensembl:ENSG00000117450(gene)|ensembl:ENST00000262746(transcript)|ensembl:ENST00000319248(transcript)|ensembl:ENST00000424390(transcript)|ensembl:ENST00000447184(transcript)|ensembl:ENST00000676549(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003723"(RNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042470"(melanosome)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q06830|rcsb pdb:2RII|rcsb pdb:3HY2|rcsb pdb:4XCS|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803|refseq:NP_001189360.1|refseq:NP_002565.1|refseq:NP_859047.1|refseq:NP_859048.1|dip:DIP-33152N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:ZM5ZXF900izH81QVqgd2+opwMrs9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P24928 intact:EBI-6152703 intact:EBI-295301|uniprotkb:A6NN93|uniprotkb:B9EH88|uniprotkb:Q6NX41|intact:EBI-17957133|intact:EBI-14758660|intact:EBI-13324911|intact:EBI-23311874 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:rpb1_human(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:POLR2(gene name synonym)|uniprotkb:RNA-directed RNA polymerase II subunit RPB1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_000928.1|mint:P24928|dip:DIP-29011N|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0019900"(kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:2GHQ|rcsb pdb:2GHT|rcsb pdb:2LTO|rcsb pdb:3D9K|rcsb pdb:3D9L|rcsb pdb:3D9M|rcsb pdb:3D9N|rcsb pdb:3D9O|rcsb pdb:3D9P|rcsb pdb:4JXT|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5M3H|rcsb pdb:5M3J|rcsb pdb:6DRD|rcsb pdb:6F5P|rcsb pdb:6G0R|rcsb pdb:6IC8|rcsb pdb:6IC9|rcsb pdb:6O9L|rcsb pdb:6Q5Y|rcsb pdb:6XKB|rcsb pdb:6XRE|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:Si2fgh4AMaNtlzvSQhvsuPusX7s9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P31943 intact:EBI-6152703 intact:EBI-351590|uniprotkb:Q6IBM4|uniprotkb:B3KW86|uniprotkb:D3DWQ2|ensembl:ENSP00000349168|ensembl:ENSP00000377082|ensembl:ENSP00000397797|ensembl:ENSP00000492076|ensembl:ENSP00000495786 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:hnrh1_human(display_long)|uniprotkb:HNRNPH1(gene name)|psi-mi:HNRNPH1(display_short)|uniprotkb:HNRPH(gene name synonym)|uniprotkb:HNRPH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_005511.1|refseq:NP_001244222.1|ensembl:ENSG00000169045(gene)|ensembl:ENSG00000284254(gene)|ensembl:ENST00000356731(transcript)|ensembl:ENST00000393432(transcript)|ensembl:ENST00000442819(transcript)|ensembl:ENST00000638505(transcript)|ensembl:ENST00000643310(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P31943|rcsb pdb:2LXU|rcsb pdb:6DHS|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|refseq:XP_016864904.1|refseq:XP_016864905.1|refseq:XP_016864906.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:htzqOB7Mmjm+C/KTTaFqh54Rm/89606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q93008 intact:EBI-6152703 intact:EBI-302524|intact:EBI-1058656|intact:EBI-28978998|ensembl:ENSP00000367558|uniprotkb:O75550|uniprotkb:Q8WWT3|uniprotkb:Q8WX12 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:usp9x_human(display_long)|uniprotkb:USP9X(gene name)|psi-mi:USP9X(display_short)|uniprotkb:DFFRX(gene name synonym)|uniprotkb:USP9(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease FAF-X(gene name synonym)|uniprotkb:Deubiquitinating enzyme FAF-X(gene name synonym)|uniprotkb:Fat facets protein-related, X-linked(gene name synonym)|uniprotkb:Ubiquitin-specific protease 9, X chromosome(gene name synonym)|uniprotkb:FAM(gene name synonym)|uniprotkb:Fat facets in mammals(gene name synonym)|uniprotkb:Ubiquitin thioesterase FAF-X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 ensembl:ENSG00000124486(gene)|ensembl:ENST00000378308(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007292"(female gamete generation)|go:"GO:0008104"(protein localization)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030426"(growth cone)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|reactome:R-HSA-2173795|reactome:R-HSA-5689880|reactome:R-HSA-8866652|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9033241|reactome:R-HSA-977225|go:"GO:0048675"(axon extension)|refseq:NP_001034679.2|refseq:NP_001034680.2|go:"GO:0050821"(protein stabilization)|go:"GO:0051301"(cell division)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0071947"(protein deubiquitination involved in ubiquitin-dependent protein catabolic process)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018200|interpro:IPR021905|interpro:IPR028889|interpro:IPR031226|interpro:IPR038765|mint:Q93008|rcsb pdb:5VBD|rcsb pdb:5WCH|ensembl:ENST00000324545|ensembl:ENSP00000316357|ensembl:ENSP00000367558|dip:DIP-27562N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:f9AWz8rAV8rMTqcQ46VrYYLTHq89606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q9BUF5 intact:EBI-6152703 intact:EBI-356735|uniprotkb:Q9HA42|ensembl:ENSP00000318697|uniprotkb:B3KM76 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:tbb6_human(display_long)|uniprotkb:TUBB6(gene name)|psi-mi:TUBB6(display_short)|uniprotkb:Tubulin beta class V(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 ensembl:ENSG00000176014(gene)|ensembl:ENST00000317702(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|refseq:NP_115914.1|interpro:IPR036525|interpro:IPR037103|mint:Q9BUF5|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001290453.1|refseq:NP_001290454.1|refseq:NP_001290455.1|refseq:NP_001290456.1|refseq:NP_001290457.1|refseq:NP_001290458.1|refseq:NP_001290459.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:/IC9o8wSAOu+lNgq44Qqu5hEof49606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P17987 intact:EBI-6152703 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P32119 intact:EBI-6152703 intact:EBI-1266300|uniprotkb:P31945|uniprotkb:P32118|uniprotkb:P35701|uniprotkb:Q6FHG4|uniprotkb:Q92763|uniprotkb:Q9UC23|uniprotkb:A8K0C0|ensembl:ENSP00000301522 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:prdx2_human(display_long)|uniprotkb:PRDX2(gene name)|psi-mi:PRDX2(display_short)|uniprotkb:NKEFB(gene name synonym)|uniprotkb:TDPX1(gene name synonym)|uniprotkb:Thioredoxin peroxidase 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 1(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein(gene name synonym)|uniprotkb:PRP(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor B(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_005800.3|dip:DIP-39882N|ensembl:ENSG00000167815(gene)|ensembl:ENST00000301522(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0002536"(respiratory burst involved in inflammatory response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:P32119|rcsb pdb:1QMV|rcsb pdb:5B8A|rcsb pdb:5B8B|rcsb pdb:5IJT|rcsb pdb:7KIZ|rcsb pdb:7KJ0|rcsb pdb:7KJ1|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:F8+7/3HrAcJq7BjkZaig16mCOO89606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q92734 intact:EBI-6152703 intact:EBI-357061|uniprotkb:Q15656|intact:EBI-357314|uniprotkb:Q969I2|uniprotkb:D3DN49|uniprotkb:K0J5S8|uniprotkb:K0J6K2|intact:EBI-28969365|ensembl:ENSP00000240851|ensembl:ENSP00000419960|ensembl:ENSP00000420797|ensembl:ENSP00000501815|ensembl:ENSP00000502071|ensembl:ENSP00000502450|ensembl:ENSP00000502592|ensembl:ENSP00000502734|uniprotkb:G5E9V1 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:tfg_human(display_long)|uniprotkb:TFG(gene name)|psi-mi:TFG(display_short)|uniprotkb:TRK-fused gene protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_001007566.1|refseq:NP_001182407.1|refseq:NP_001182408.1|refseq:NP_006061.2|ensembl:ENSP00000240851|ensembl:ENST00000463568|ensembl:ENSP00000419504|ensembl:ENST00000476228|ensembl:ENSP00000417952|ensembl:ENSP00000420797|ensembl:ENSP00000419960|ensembl:ENST00000615993|ensembl:ENSP00000479269|ensembl:ENST00000620299|ensembl:ENSP00000479981|ensembl:ENSP00000502734|ensembl:ENST00000674645|ensembl:ENSP00000501892|ensembl:ENST00000674758|ensembl:ENSP00000502502|ensembl:ENST00000675047|ensembl:ENSP00000502497|ensembl:ENSP00000502592|ensembl:ENST00000675420|ensembl:ENSP00000502516|ensembl:ENSP00000502450|ensembl:ENST00000675543|ensembl:ENSP00000501815|ensembl:ENST00000675586|ensembl:ENSP00000502329|ensembl:ENST00000676111|ensembl:ENSP00000502139|ensembl:ENST00000676308|ensembl:ENSP00000502697|ensembl:ENSP00000502071|ensembl:ENST00000676431|ensembl:ENSP00000502698|ensembl:ENSP00000502229|refseq:XP_006713535.1|refseq:XP_006713536.1|ensembl:ENSG00000114354(gene)|ensembl:ENST00000240851(transcript)|ensembl:ENST00000487505(transcript)|ensembl:ENST00000490574(transcript)|ensembl:ENST00000674615(transcript)|ensembl:ENST00000675243(transcript)|ensembl:ENST00000675499(transcript)|ensembl:ENST00000675553(transcript)|ensembl:ENST00000676395(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR033512|interpro:IPR034857|mint:Q92734|reactome:R-HSA-204005|refseq:XP_011510636.1|refseq:XP_005247123.1|refseq:XP_016861016.1|refseq:XP_016861017.1|refseq:XP_016861018.1|refseq:XP_016861019.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:y7aghh0X3Ewgpzcx5h5nB+X2dII9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q9Y230 intact:EBI-6152703 intact:EBI-352939|ensembl:ENSP00000473172|uniprotkb:Q6FIB9|uniprotkb:Q6PK27|uniprotkb:Q9Y361|uniprotkb:B3KQ59|uniprotkb:E7ETE5|intact:EBI-1058527 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:ruvb2_human(display_long)|uniprotkb:RUVBL2(gene name)|psi-mi:RUVBL2(display_short)|uniprotkb:TIP48(gene name synonym)|uniprotkb:TIP49B(gene name synonym)|uniprotkb:CGI-46(orf name)|uniprotkb:48 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49b(gene name synonym)|uniprotkb:Repressing pontin 52(gene name synonym)|uniprotkb:51 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80J(gene name synonym)|uniprotkb:TIP60-associated protein 54-beta(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487|mint:Q9Y230|rcsb pdb:2CQA|rcsb pdb:2XSZ|rcsb pdb:3UK6|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6H7X|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|go:"GO:0140585"(promoter-enhancer loop anchoring activity)|reactome:R-HSA-3214847|ensembl:ENSG00000183207(gene)|ensembl:ENST00000595090(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000791"(euchromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006457"(protein folding)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0016573"(histone acetylation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|refseq:NP_006657.1|refseq:XP_011524632.1|refseq:NP_001308120.1|dip:DIP-28153N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:APKAWLDCJVULUP3nzqIaSLHKVN49606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q96EY1 intact:EBI-6152703 intact:EBI-356767|uniprotkb:O75472|uniprotkb:Q8WUJ6|uniprotkb:Q8WXJ3|uniprotkb:Q96D76|uniprotkb:Q96IV1|uniprotkb:Q9NYH8|uniprotkb:B2RAJ5|uniprotkb:B4DI33|uniprotkb:E7ES32|ensembl:ENSP00000262375|ensembl:ENSP00000477570 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:dnja3_human(display_long)|uniprotkb:DNAJA3(gene name)|psi-mi:DNAJA3(display_short)|uniprotkb:TID1(gene name synonym)|uniprotkb:HCA57(gene name synonym)|uniprotkb:Tumorous imaginal discs protein Tid56 homolog(gene name synonym)|uniprotkb:DnaJ protein Tid-1(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 57(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_001273445.1|refseq:NP_001128582.1|refseq:NP_005138.3|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0106137"(IkappaB kinase complex binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|mint:Q96EY1|rcsb pdb:2CTT|rcsb pdb:2DN9|rcsb pdb:6IWS|ensembl:ENSG00000103423(gene)|ensembl:ENSG00000276726(gene)|ensembl:ENST00000262375(transcript)|ensembl:ENST00000612103(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005133"(interferon-gamma receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006457"(protein folding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007569"(cell aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|dip:DIP-33870N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:WnRYdQ9E3yGbSlq1SSGTX9k+3uA9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q9P1Q0 intact:EBI-6152703 intact:EBI-5235744|uniprotkb:Q5VIR5|uniprotkb:Q86YF7|uniprotkb:Q8N6G3|uniprotkb:Q9NPV0|uniprotkb:Q9NT07|uniprotkb:Q9NUJ0|ensembl:ENSP00000272322 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:vps54_human(display_long)|uniprotkb:VPS54(gene name)|psi-mi:VPS54(display_short)|uniprotkb:HCC8(gene name synonym)|uniprotkb:Hepatocellular carcinoma protein 8(gene name synonym)|uniprotkb:Tumor antigen HOM-HCC-8(gene name synonym)|uniprotkb:Tumor antigen SLP-8p(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_001005739.1|refseq:NP_057600.2|ensembl:ENSP00000272322|ensembl:ENST00000354504|ensembl:ENSP00000346499|ensembl:ENST00000409558|ensembl:ENSP00000386980|dip:DIP-61627N|ensembl:ENSG00000143952(gene)|ensembl:ENST00000272322(transcript)|go:"GO:0000938"(GARP complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007041"(lysosomal transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0040008"(regulation of growth)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050881"(musculoskeletal movement)|go:"GO:0060052"(neurofilament cytoskeleton organization)|interpro:IPR012501(Vps54-like)|interpro:IPR019515|interpro:IPR039745|reactome:R-HSA-6811440 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:73qrDr3X9MJhaJdB9vVTJBsD/pA9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P55795 intact:EBI-6152703 intact:EBI-352823|ensembl:ENSP00000361927|uniprotkb:Q9HHA7|uniprotkb:A1L400 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:hnrh2_human(display_long)|uniprotkb:HNRNPH2(gene name)|psi-mi:HNRNPH2(display_short)|uniprotkb:FTP3(gene name synonym)|uniprotkb:HNRPH2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein H'(gene name synonym)|uniprotkb:FTP-3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 ensembl:ENSG00000126945(gene)|ensembl:ENST00000316594(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P55795|rcsb pdb:1WEZ|rcsb pdb:1WG5|rcsb pdb:6DG1|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001027565.1|refseq:NP_062543.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:811j5syFsbk/QSaZv/ag9QsFUEQ9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P14625 intact:EBI-6152703 intact:EBI-359129|uniprotkb:Q96A97|ensembl:ENSP00000299767 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:enpl_human(display_long)|uniprotkb:HSP90B1(gene name)|psi-mi:HSP90B1(display_short)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:GRP94(gene name synonym)|uniprotkb:gp96 homolog(gene name synonym)|uniprotkb:Tumor rejection antigen 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_003290.1|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P14625|rcsb pdb:4NH9|reactome:R-HSA-1679131|reactome:R-HSA-3000480|reactome:R-HSA-381183|reactome:R-HSA-381426|reactome:R-HSA-6785807|reactome:R-HSA-8957275|ensembl:ENSG00000166598(gene)|ensembl:ENST00000299767(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031247"(actin rod assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|dip:DIP-36060N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:m5CdlplqVyMUWYe75aKDuMzztMY9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:O00232 intact:EBI-6152703 intact:EBI-359733|uniprotkb:Q53HA2|uniprotkb:Q6P053|ensembl:ENSP00000348442|uniprotkb:A6NP15 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:psd12_human(display_long)|uniprotkb:PSMD12(gene name)|psi-mi:PSMD12(display_short)|uniprotkb:26S proteasome regulatory subunit p55(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_002807.1|refseq:NP_001303270.1|ensembl:ENSG00000197170(gene)|ensembl:ENST00000356126(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035297|interpro:IPR036388|interpro:IPR036390|interpro:IPR040134|interpro:IPR040896|mint:O00232|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|rcsb pdb:5VFS|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-5687128|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_777360.1|dip:DIP-27549N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:4tzcvfL/EqQRcUpoMtxVU0WC+TU9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:O94979 intact:EBI-6152703 intact:EBI-1767898|uniprotkb:Q17RR5|uniprotkb:Q5H9P6|uniprotkb:Q5XG74|uniprotkb:Q659G7|uniprotkb:Q6ZU90|uniprotkb:Q7LCX9|uniprotkb:Q86TJ0|uniprotkb:Q8IZH4|uniprotkb:Q9P048|uniprotkb:Q9P0A6|uniprotkb:Q9UM05|uniprotkb:Q9UM06|uniprotkb:B7ZKZ7|uniprotkb:B7ZL00|uniprotkb:B4DIW6|uniprotkb:H7C2W3|ensembl:ENSP00000347329|ensembl:ENSP00000378721|ensembl:ENSP00000400926 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:sc31a_human(display_long)|uniprotkb:SEC31A(gene name)|psi-mi:SEC31A(display_short)|uniprotkb:KIAA0905(gene name synonym)|uniprotkb:SEC31L1(gene name synonym)|uniprotkb:HSPC275(orf name)|uniprotkb:HSPC334(orf name)|uniprotkb:SEC31-related protein A(gene name synonym)|uniprotkb:SEC31-like protein 1(gene name synonym)|uniprotkb:ABP125(gene name synonym)|uniprotkb:ABP130(gene name synonym)|uniprotkb:Web1-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_001070674.1|refseq:NP_001070675.1|refseq:NP_001070676.1|refseq:NP_057295.2|refseq:NP_001305048.1|refseq:NP_001305049.1|refseq:NP_001287673.1|refseq:NP_001287674.1|refseq:NP_001177978.1|dip:DIP-40438N|ensembl:ENSG00000138674(gene)|ensembl:ENST00000355196(transcript)|ensembl:ENST00000395310(transcript)|ensembl:ENST00000448323(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030120"(vesicle coat)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051592"(response to calcium ion)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024298|interpro:IPR036322|interpro:IPR040251|mint:O94979|rcsb pdb:3WXA|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-381038|reactome:R-HSA-983170 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:MvtQi/4RmQ0siNtNoYH6k1rPv1Y9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P35579 intact:EBI-6152703 intact:EBI-350338|uniprotkb:O60805|ensembl:ENSP00000216181|uniprotkb:Q86T83|intact:EBI-1054343|uniprotkb:A8K6E4|uniprotkb:Q60FE2 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_002464.1|ensembl:ENSG00000100345(gene)|ensembl:ENST00000216181(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|refseq:XP_011528499.1|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0097513"(myosin II filament)|go:"GO:1903919"(negative regulation of actin filament severing)|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:O60884 intact:EBI-6152703 intact:EBI-352957|ensembl:ENSP00000314030|uniprotkb:O14711|uniprotkb:B2R7L7 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:dnja2_human(display_long)|uniprotkb:DNAJA2(gene name)|psi-mi:DNAJA2(display_short)|uniprotkb:HIRIP4(gene name synonym)|uniprotkb:CPR3(gene name synonym)|uniprotkb:HIRA-interacting protein 4(gene name synonym)|uniprotkb:Cell cycle progression restoration gene 3 protein(gene name synonym)|uniprotkb:Dnj3(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 ensembl:ENSG00000069345(gene)|ensembl:ENST00000317089(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:O60884|reactome:R-HSA-3371497|interpro:IPR018253|refseq:NP_005871.1|dip:DIP-33143N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:c+JdHn0cKVKqRZCvK6DRYWs+zkQ9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q9BUJ2 intact:EBI-6152703 intact:EBI-1018153|uniprotkb:O76022|uniprotkb:Q6ZSZ0|uniprotkb:Q7L8P4|uniprotkb:Q8N6Z4|uniprotkb:Q96G37|uniprotkb:Q9HAL3|uniprotkb:Q9UG75|intact:EBI-3183399|intact:EBI-2339292|uniprotkb:B3KMW7|ensembl:ENSP00000375863|intact:EBI-2563529 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:hnrl1_human(display_long)|uniprotkb:E1BAP5(gene name synonym)|uniprotkb:HNRNPUL1(gene name)|psi-mi:HNRNPUL1(display_short)|uniprotkb:HNRPUL1(gene name synonym)|uniprotkb:Adenovirus early region 1B-associated protein 5(gene name synonym)|uniprotkb:E1B-55 kDa-associated protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_008971.2|refseq:NP_653333.1|go:"GO:0009615"(response to virus)|go:"GO:0019899"(enzyme binding)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027025|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q9BUJ2|reactome:R-HSA-72163|ensembl:ENSG00000105323(gene)|ensembl:ENST00000392006(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|refseq:NP_001308140.1|refseq:NP_001308137.1|dip:DIP-39419N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:IahA7SVR1NmvldrWKQlAwApinQE9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q9Y265 intact:EBI-6152703 intact:EBI-353675|uniprotkb:P82276|uniprotkb:Q1KMR0|uniprotkb:Q53HK5|uniprotkb:Q53HL7|uniprotkb:Q53Y27|uniprotkb:Q9BSX9|uniprotkb:B2R5S0|ensembl:ENSP00000318297|ensembl:ENSP00000494621 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:ruvb1_human(display_long)|uniprotkb:RUVBL1(gene name)|psi-mi:RUVBL1(display_short)|uniprotkb:NMP238(gene name synonym)|uniprotkb:TIP49(gene name synonym)|uniprotkb:TIP49A(gene name synonym)|uniprotkb:49 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49a(gene name synonym)|uniprotkb:Pontin 52(gene name synonym)|uniprotkb:Nuclear matrix protein 238(gene name synonym)|uniprotkb:54 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80H(gene name synonym)|uniprotkb:TIP60-associated protein 54-alpha(gene name synonym)|uniprotkb:INO80 complex subunit H(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_003698.1|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:Q9Y265|rcsb pdb:2C9O|rcsb pdb:2XSZ|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|reactome:R-HSA-201722|reactome:R-HSA-3214847|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5696394|reactome:R-HSA-606279|ensembl:ENSG00000175792(gene)|ensembl:ENSG00000284901(gene)|ensembl:ENST00000322623(transcript)|ensembl:ENST00000643444(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|refseq:NP_001306013.1|dip:DIP-29937N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:+FA/xQTUldQoWGRgad9U8vZpTHw9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P53992 intact:EBI-6152703 intact:EBI-81134|uniprotkb:Q8WV25|ensembl:ENSP00000321845|ensembl:ENSP00000343405|uniprotkb:B4DZT4 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:sc24c_human(display_long)|uniprotkb:SEC24C(gene name)|psi-mi:SEC24C(display_short)|uniprotkb:KIAA0079(gene name synonym)|uniprotkb:SEC24-related protein C(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|mint:P53992|rcsb pdb:3EH2|rcsb pdb:6PU1|reactome:R-HSA-1655829|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-983170|reactome:R-HSA-5694530|ensembl:ENSG00000176986(gene)|ensembl:ENST00000339365(transcript)|ensembl:ENST00000345254(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030127"(COPII vesicle coat)|refseq:NP_004913.2|refseq:NP_940999.1|dip:DIP-30981N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:kOKJkIWFOlIpRFLj5JshAGqAg6s9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P49368 intact:EBI-6152703 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P23246 intact:EBI-6152703 intact:EBI-355453|uniprotkb:P30808|uniprotkb:Q5SZ71|ensembl:ENSP00000349748 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:sfpq_human(display_long)|uniprotkb:SFPQ(gene name)|psi-mi:SFPQ(display_short)|uniprotkb:PSF(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:100 kDa DNA-pairing protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_005057.1|ensembl:ENSG00000116560(gene)|ensembl:ENST00000357214(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0005634"(nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0048511"(rhythmic process)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034525|interpro:IPR034526|interpro:IPR035979|mint:P23246|rcsb pdb:4WII|rcsb pdb:4WIJ|rcsb pdb:4WIK|rcsb pdb:5WPA|rcsb pdb:6NCQ|rcsb pdb:6OWJ|rcsb pdb:6WMZ|rcsb pdb:7LRQ|rcsb pdb:7LRU|reactome:R-HSA-8849468|reactome:R-HSA-9635465|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|refseq:XP_005271169.1|refseq:XP_005271170.1|refseq:XP_005271172.1|refseq:XP_016857542.1|refseq:XP_016857543.1|dip:DIP-31272N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:B7mSc6tthLbSHo0qz0SMZBSl3HA9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q9UBS4 intact:EBI-6152703 intact:EBI-713113|ensembl:ENSP00000265028|ensembl:ENSP00000414398|uniprotkb:Q542Y5|uniprotkb:Q542Y9|uniprotkb:Q6IAQ8|uniprotkb:Q96JC6 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:djb11_human(display_long)|uniprotkb:HDJ9(gene name synonym)|uniprotkb:DnaJ protein homolog 9(gene name synonym)|uniprotkb:ER-associated Hsp40 co-chaperone(gene name synonym)|uniprotkb:ER-associated DNAJ(gene name synonym)|uniprotkb:HEDJ(gene name synonym)|uniprotkb:Human DnaJ protein 9(gene name synonym)|uniprotkb:PWP1-interacting protein 4(gene name synonym)|uniprotkb:APOBEC1-binding protein 2(gene name synonym)|uniprotkb:PSEC0121(orf name)|uniprotkb:DNAJB11(gene name)|psi-mi:DNAJB11(display_short)|uniprotkb:EDJ(gene name synonym)|uniprotkb:ERJ3(gene name synonym)|uniprotkb:UNQ537/PRO1080(orf name)|uniprotkb:Endoplasmic reticulum DNA J domain-containing protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 ensembl:ENSG00000090520(gene)|ensembl:ENST00000265028(transcript)|ensembl:ENST00000439351(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0016020"(membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0101031"(chaperone complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|mint:Q9UBS4|reactome:R-HSA-381038|go:"GO:0006457"(protein folding)|refseq:NP_057390.1|dip:DIP-29678N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:B8jV6uvPmoGzOEpe4qrMiYloSok9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:O95831 intact:EBI-6152703 intact:EBI-356440|uniprotkb:Q5JUZ7|uniprotkb:Q6I9X6|uniprotkb:Q9Y3I3|uniprotkb:Q9Y3I4|uniprotkb:A4QPB4|uniprotkb:B1ALN1|uniprotkb:B2RB08|intact:EBI-2561858|uniprotkb:D3DTE9|uniprotkb:Q1L6K6|uniprotkb:Q2QKE4|uniprotkb:Q1L6K4|ensembl:ENSP00000287295|uniprotkb:E9PRR0 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:aifm1_human(display_long)|uniprotkb:AIFM1(gene name)|psi-mi:AIFM1(display_short)|uniprotkb:AIF(gene name synonym)|uniprotkb:PDCD8(gene name synonym)|uniprotkb:Programmed cell death protein 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_001124319.1|refseq:NP_004199.1|refseq:NP_665811.1|refseq:NP_001124318.2|rcsb pdb:5FS6|rcsb pdb:5FS7|rcsb pdb:5FS8|rcsb pdb:5FS9|rcsb pdb:5KVH|rcsb pdb:5KVI|ensembl:ENSG00000156709(gene)|ensembl:ENST00000287295(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0030182"(neuron differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0071949"(FAD binding)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1904045"(cellular response to aldosterone)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR029324|interpro:IPR036188|mint:O95831|rcsb pdb:1M6I|rcsb pdb:4BUR|rcsb pdb:4BV6|rcsb pdb:4FDC|rcsb pdb:4LII|rcsb pdb:5FMH|dip:DIP-32975N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:tAY+mPStfDGbCN4OpvHF4ljQ69I9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q9BQE3 intact:EBI-6152703 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:O00165 intact:EBI-6152703 intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|ensembl:ENSG00000143575(gene)|ensembl:ENST00000328703(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q8N163 intact:EBI-6152703 intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|ensembl:ENSP00000310670|ensembl:ENSP00000373930|uniprotkb:B2RB79|uniprotkb:D3DSR6 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_066997.3|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|interpro:IPR028811|mint:Q8N163|reactome:R-HSA-3371453|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|dip:DIP-38122N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q13885 intact:EBI-6152703 intact:EBI-711595|ensembl:ENSP00000369703|uniprotkb:Q6FGZ8|uniprotkb:Q8IWR2 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:tbb2a_human(display_long)|uniprotkb:TUBB2A(gene name)|psi-mi:TUBB2A(display_short)|uniprotkb:TUBB2(gene name synonym)|uniprotkb:Tubulin beta class IIa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-389957|reactome:R-HSA-983189|reactome:R-HSA-9668328|ensembl:ENSG00000137267(gene)|ensembl:ENST00000333628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q13885|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|refseq:NP_001060.1|refseq:NP_001297244.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:O76031 intact:EBI-6152703 intact:EBI-1052667|uniprotkb:A1L428|uniprotkb:A8K8F1|uniprotkb:Q9H4D9|uniprotkb:B9EGI8|ensembl:ENSP00000300107 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:clpx_human(display_long)|uniprotkb:CLPX(gene name)|psi-mi:CLPX(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_006651.2|ensembl:ENSG00000166855(gene)|ensembl:ENST00000300107(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009368"(endopeptidase Clp complex)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004487(ClpX, ATPase regulatory subunit)|interpro:IPR010603(Zinc finger, C4-type)|interpro:IPR019489|interpro:IPR027417|go:"GO:0009841"(mitochondrial endopeptidase Clp complex)|mint:O76031|dip:DIP-50293N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:+SOis7raPEZqqeel6Y6dOWJcLj49606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q92841 intact:EBI-6152703 intact:EBI-746012|uniprotkb:Q69YT1|uniprotkb:Q6ICD6|uniprotkb:H3BLZ8|uniprotkb:B1AHM0|ensembl:ENSP00000385536 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:ddx17_human(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:RNA-dependent helicase p72(gene name synonym)|uniprotkb:DEAD box protein p72(gene name synonym)|uniprotkb:DDX17(gene name)|psi-mi:DDX17(display_short)|uniprotkb:DEAD box protein p82(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_006377.2|ensembl:ENSG00000100201(gene)|ensembl:ENST00000403230(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q92841|rcsb pdb:6UV0|rcsb pdb:6UV1|rcsb pdb:6UV2|rcsb pdb:6UV3|rcsb pdb:6UV4|reactome:R-HSA-3899300|dip:DIP-29843N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:3UhUuhRSZg/zlM7UPDKYCqNmUho9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:O75475 intact:EBI-6152703 intact:EBI-1801773|uniprotkb:O00256|uniprotkb:O95368|uniprotkb:Q6P391|uniprotkb:Q86YB9|uniprotkb:Q9NZI3|uniprotkb:Q9UER6|uniprotkb:D3DRI9|ensembl:ENSP00000370109|ensembl:ENSP00000370114 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:psip1_human(display_long)|uniprotkb:PSIP1(gene name)|psi-mi:PSIP1(display_short)|uniprotkb:DFS70(gene name synonym)|uniprotkb:LEDGF(gene name synonym)|uniprotkb:PSIP2(gene name synonym)|uniprotkb:Lens epithelium-derived growth factor(gene name synonym)|uniprotkb:Transcriptional coactivator p75/p52(gene name synonym)|uniprotkb:Dense fine speckles 70 kDa protein(gene name synonym)|uniprotkb:CLL-associated antigen KW-7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_001304827.1|refseq:NP_001304829.1|refseq:NP_001121689.1|refseq:NP_066967.3|refseq:NP_150091.2|dip:DIP-46656N|ensembl:ENSG00000164985(gene)|ensembl:ENST00000380733(transcript)|ensembl:ENST00000380738(transcript)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009408"(response to heat)|go:"GO:0034399"(nuclear periphery)|go:"GO:0035327"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000313(PWWP)|interpro:IPR021567|interpro:IPR035441|interpro:IPR035496|interpro:IPR036218|mint:O75475|rcsb pdb:1Z9E|rcsb pdb:2B4J|rcsb pdb:2M16|rcsb pdb:2MSR|rcsb pdb:2MTN|rcsb pdb:2N3A|rcsb pdb:3F9K|rcsb pdb:3HPG|rcsb pdb:3HPH|rcsb pdb:3U88|rcsb pdb:3ZEH|rcsb pdb:4FU6|rcsb pdb:5N88|rcsb pdb:5OYM|rcsb pdb:5YI9|rcsb pdb:6EMO|rcsb pdb:6EMP|rcsb pdb:6EMQ|rcsb pdb:6EMR|rcsb pdb:6S01|rcsb pdb:6TRJ|rcsb pdb:6TVM|rcsb pdb:6Z2Y|reactome:R-HSA-162592|reactome:R-HSA-164843|reactome:R-HSA-175567|reactome:R-HSA-177539|reactome:R-HSA-180689|reactome:R-HSA-180910 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:MRtOw4kH/FxVku25dO5RQiNTjDA9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q05639 intact:EBI-6152703 intact:EBI-354943|ensembl:ENSP00000217182|uniprotkb:P54266|uniprotkb:Q0VGC7|uniprotkb:B5BUF3|uniprotkb:E1P5J1 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:ef1a2_human(display_long)|uniprotkb:EEF1A2(gene name)|psi-mi:EEF1A2(display_short)|uniprotkb:EEF1AL(gene name synonym)|uniprotkb:STN(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-2(gene name synonym)|uniprotkb:Statin-S1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 ensembl:ENSG00000101210(gene)|ensembl:ENST00000217182(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0090218"(positive regulation of lipid kinase activity)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:Q05639|rcsb pdb:3C5J|reactome:R-HSA-156842|refseq:NP_001949.1|dip:DIP-40060N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:vFXfcSRokxKo5RW0tRE1qEK0NKw9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:A8MVJ9 intact:EBI-6152703 intact:EBI-6152775 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:hpf1l_human(display_long) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 mint:A8MVJ9|interpro:IPR019361|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0042393"(histone binding)|go:"GO:0072572"(poly-ADP-D-ribose binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:5l1U+uPhO4bJjJY0H9YQC8YWrRs9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q6Q759 intact:EBI-6152703 intact:EBI-6152750|ensembl:ENSP00000337804|uniprotkb:Q9NT21|uniprotkb:Q8NAZ1 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:spg17_human(display_long)|uniprotkb:Projection protein PF6 homolog(gene name synonym)|uniprotkb:SPAG17(gene name)|psi-mi:SPAG17(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 ensembl:ENSG00000155761(gene)|ensembl:ENST00000336338(transcript)|go:"GO:0003351"(epithelial cilium movement involved in extracellular fluid movement)|go:"GO:0005576"(extracellular region)|go:"GO:0005874"(microtubule)|go:"GO:0031514"(motile cilium)|go:"GO:1904158"(axonemal central apparatus assembly)|go:"GO:1990716"(axonemal central apparatus)|interpro:IPR026173|refseq:NP_996879.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:MFSwSmkAnM2sDnTLd8fes2VcGt09606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q5VTE0 intact:EBI-6152703 intact:EBI-877809 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:ef1a3_human(display_long)|uniprotkb:EEF1A1P5(gene name)|psi-mi:EEF1A1P5(display_short)|uniprotkb:Eukaryotic elongation factor 1 A-like 3(gene name synonym)|uniprotkb:EEF1AL3(gene name synonym)|uniprotkb:Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR031157|reactome:R-HSA-156842|interpro:IPR027417 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:3t6tj3i+3CKTC1NsrHyBkeoRK789606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P78347 intact:EBI-6152703 intact:EBI-359622|uniprotkb:Q75M88|uniprotkb:O14743|uniprotkb:O15359|uniprotkb:O43546|uniprotkb:O43588|uniprotkb:O43589|uniprotkb:Q9BSZ4|uniprotkb:Q86U51|uniprotkb:Q75M85|uniprotkb:Q75M86|uniprotkb:Q75M87|ensembl:ENSP00000460070 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:gtf2i_human(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_001509.3|refseq:NP_127492.1|refseq:NP_127493.1|refseq:NP_127494.1|ensembl:ENSG00000263001(gene)|ensembl:ENST00000573035(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0100026"(positive regulation of DNA repair by transcription from RNA polymerase II promoter)|interpro:IPR004212(GTF2I-like repeat)|interpro:IPR016659(Transcription factor II-I)|mint:P78347|rcsb pdb:2D9B|rcsb pdb:2DN4|rcsb pdb:2ED2|rcsb pdb:2EJE|interpro:IPR036647|refseq:NP_001157108.1|refseq:NP_001267729.1|dip:DIP-24252N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:DqfrIS0Ey+XvZfTXmk9KQzBtQo49606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P43243 intact:EBI-6152703 intact:EBI-352602|ensembl:ENSP00000378284|ensembl:ENSP00000482895|uniprotkb:Q9UHW0|uniprotkb:Q9UQ27|uniprotkb:D3DQC3|uniprotkb:B7ZAV5 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:matr3_human(display_long)|uniprotkb:KIAA0723(gene name synonym)|uniprotkb:MATR3(gene name)|psi-mi:MATR3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 ensembl:ENSG00000015479(gene)|ensembl:ENST00000394805(transcript)|ensembl:ENST00000618441(transcript)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:P43243|refseq:NP_001181883.1|refseq:NP_001181884.1|refseq:NP_061322.2|refseq:NP_954659.1|refseq:NP_001181885.1|refseq:NP_001269207.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:3UZlyCZHgdr1SBgUctv9Ev7XBSQ9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q3ZCQ8 intact:EBI-6152703 intact:EBI-355175|uniprotkb:Q6QA00|uniprotkb:Q96FJ5|uniprotkb:Q96GY2|uniprotkb:Q9H370|intact:EBI-2554785|uniprotkb:Q330K1|ensembl:ENSP00000475531 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:tim50_human(display_long)|uniprotkb:TIMM50(gene name)|psi-mi:TIMM50(display_short)|uniprotkb:TIM50(gene name synonym)|uniprotkb:PRO1512(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_001001563.1|ensembl:ENSG00000105197(gene)|ensembl:ENST00000607714(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003723"(RNA binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005134"(interleukin-2 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007006"(mitochondrial membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR004274(NLI interacting factor)|interpro:IPR023214|interpro:IPR027111|interpro:IPR036412|mint:Q3ZCQ8|reactome:R-HSA-1268020|refseq:NP_001316488.1|dip:DIP-34058N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:fOPV33h12YhAq9jj0bVno01Q+6g9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P48643 intact:EBI-6152703 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P23526 intact:EBI-6152703 intact:EBI-1053240|uniprotkb:Q96A36|ensembl:ENSP00000217426|uniprotkb:B3KUN3|uniprotkb:F5H737|uniprotkb:A8K307|uniprotkb:E1P5P2 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:sahh_human(display_long)|uniprotkb:S-adenosyl-L-homocysteine hydrolase(gene name synonym)|uniprotkb:AHCY(gene name)|psi-mi:AHCY(display_short)|uniprotkb:SAHH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_000678.1|refseq:NP_001155238.1|ensembl:ENSG00000101444(gene)|ensembl:ENST00000217426(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002439"(chronic inflammatory response to antigenic stimulus)|go:"GO:0004013"(adenosylhomocysteinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0019510"(S-adenosylhomocysteine catabolic process)|go:"GO:0030554"(adenyl nucleotide binding)|go:"GO:0033353"(S-adenosylmethionine cycle)|go:"GO:0042470"(melanosome)|go:"GO:0042745"(circadian sleep/wake cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000043(S-adenosyl-L-homocysteine hydrolase)|interpro:IPR015878(S-adenosyl-L-homocysteine hydrolase, NAD binding)|interpro:IPR020082|interpro:IPR036291|interpro:IPR042172|mint:P23526|rcsb pdb:1A7A|rcsb pdb:1LI4|refseq:XP_011526961.1|refseq:XP_005260374.1|refseq:NP_001309013.1|refseq:NP_001309014.1|rcsb pdb:3NJ4|rcsb pdb:4PFJ|rcsb pdb:4PGF|rcsb pdb:4YVF|rcsb pdb:5W49|rcsb pdb:5W4B|reactome:R-HSA-156581|reactome:R-HSA-1614635|reactome:R-HSA-2408508|reactome:R-HSA-5578997|refseq:XP_016883197.1|refseq:XP_016883198.1|dip:DIP-50557N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:+y7rwgw9EIMaVrkt4/9kbZM44sg9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P53396 intact:EBI-6152703 intact:EBI-1042794|uniprotkb:Q13037|uniprotkb:Q9BRL0|uniprotkb:B4E3P0|uniprotkb:B4DIM0|ensembl:ENSP00000253792|ensembl:ENSP00000466259 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:acly_human(display_long)|uniprotkb:ACLY(gene name)|psi-mi:ACLY(display_short)|uniprotkb:"ATP-citrate (pro-S-)-lyase"(gene name synonym)|uniprotkb:Citrate cleavage enzyme(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_001087.2|refseq:NP_942127.1|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR003781(CoA-binding)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR014608(ATP-citrate synthase)|ensembl:ENSG00000131473(gene)|ensembl:ENST00000352035(transcript)|ensembl:ENST00000590151(transcript)|go:"GO:0003878"(ATP citrate synthase activity)|interpro:IPR016102(Succinyl-CoA synthetase-like)|go:"GO:0005524"(ATP binding)|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR017440(ATP-citrate lyase/succinyl-CoA ligase, active site)|interpro:IPR017866|interpro:IPR032263|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0046872"(metal ion binding)|interpro:IPR033847|rcsb pdb:6O0H|interpro:IPR036291|rcsb pdb:6POE|interpro:IPR036969|rcsb pdb:6POF|rcsb pdb:6QFB|mint:P53396|rcsb pdb:6UI9|rcsb pdb:6UIA|rcsb pdb:3MWD|rcsb pdb:6UUW|rcsb pdb:6UUZ|rcsb pdb:6UV5|rcsb pdb:6Z2H|rcsb pdb:7LIW|rcsb pdb:7LJ9|rcsb pdb:7LLA|reactome:R-HSA-163765|rcsb pdb:3MWE|reactome:R-HSA-6798695|reactome:R-HSA-75105|rcsb pdb:3PFF|rcsb pdb:5TDE|rcsb pdb:5TDF|rcsb pdb:5TDM|rcsb pdb:5TDZ|rcsb pdb:5TE1|rcsb pdb:5TEQ|rcsb pdb:5TES|rcsb pdb:5TET|rcsb pdb:6HXH|rcsb pdb:6HXK|rcsb pdb:6HXL|rcsb pdb:6HXM|refseq:XP_005257452.1|refseq:NP_001290203.1|refseq:NP_001290204.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:NaxO5aRi08GTrEV9aIboUdTlpAs9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P49327 intact:EBI-6152703 intact:EBI-356658|uniprotkb:Q4LE83|uniprotkb:Q13479|uniprotkb:Q16702|uniprotkb:Q6P4U5|uniprotkb:Q6SS02|uniprotkb:Q969R1|uniprotkb:Q96C68|uniprotkb:Q96IT0|ensembl:ENSP00000304592 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:fas_human(display_long)|uniprotkb:FASN(gene name)|psi-mi:FASN(display_short)|uniprotkb:FAS(gene name synonym)|uniprotkb:Type I fatty acid synthase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_004095.4|ensembl:ENSG00000169710(gene)|ensembl:ENST00000306749(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003723"(RNA binding)|go:"GO:0004313"([acyl-carrier-protein] S-acetyltransferase activity)|go:"GO:0004314"([acyl-carrier-protein] S-malonyltransferase activity)|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0004316"("3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity")|go:"GO:0004317"(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0004320"(oleoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0008659"("(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity")|go:"GO:0008693"(3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0016020"(membrane)|go:"GO:0016295"(myristoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0016296"(palmitoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042470"(melanosome)|go:"GO:0042587"(glycogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0047451"(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0102131"(obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity)|go:"GO:0102132"(obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity)|interpro:IPR001031(Thioesterase)|interpro:IPR001227(Acyl transferase region)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR013968(Polyketide synthase, KR)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR018201|interpro:IPR020806|interpro:IPR020807|interpro:IPR020841|interpro:IPR020843|interpro:IPR029058|interpro:IPR029063|interpro:IPR032821|interpro:IPR036291|interpro:IPR036736|interpro:IPR042104|mint:P49327|rcsb pdb:1XKT|rcsb pdb:2CG5|rcsb pdb:2JFD|rcsb pdb:2JFK|rcsb pdb:2PX6|rcsb pdb:3HHD|rcsb pdb:3TJM|rcsb pdb:4PIV|rcsb pdb:4W82|rcsb pdb:4W9N|rcsb pdb:4Z49|rcsb pdb:5C37|rcsb pdb:6NNA|reactome:R-HSA-163765|reactome:R-HSA-199220|reactome:R-HSA-2426168|reactome:R-HSA-75105|reactome:R-HSA-9029558|go:"GO:0047117"("enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity")|refseq:XP_011521840.1|dip:DIP-33681N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:bQYEH/uQ6l+SPzLBDNCV5yP+yzs9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P08238 intact:EBI-6152703 intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:wOsW7C10v2oMsM+REE38K6PAan09606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P30876 intact:EBI-6152703 intact:EBI-394712|uniprotkb:Q8IZ61|uniprotkb:A8K1A8|ensembl:ENSP00000312735|ensembl:ENSP00000370625 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:rpb2_human(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit B(gene name synonym)|uniprotkb:RNA polymerase II subunit B2(gene name synonym)|uniprotkb:RNA polymerase II subunit 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_000929.1|refseq:NP_001290197.1|refseq:NP_001290198.1|ensembl:ENSG00000047315(gene)|ensembl:ENST00000314595(transcript)|ensembl:ENST00000381227(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:P30876|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32910N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:YhEjtfLk2QnbRPefOp8ZHX0ejak9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q9NQI0 intact:EBI-6152703 intact:EBI-6152766|uniprotkb:Q9NYB1|uniprotkb:Q86VX0|uniprotkb:Q5M7Z3|uniprotkb:A8K8Q2|uniprotkb:Q9NT92|uniprotkb:B3KSF4|uniprotkb:E9PCD8|uniprotkb:D6RDK4|ensembl:ENSP00000424838 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:ddx4_human(display_long)|uniprotkb:DEAD box protein 4(gene name synonym)|uniprotkb:VASA(gene name synonym)|uniprotkb:Vasa homolog(gene name synonym)|uniprotkb:DDX4(gene name)|psi-mi:DDX4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_001160006.1|refseq:NP_001136021.1|refseq:NP_001160005.1|refseq:NP_077726.1|ensembl:ENSG00000152670(gene)|ensembl:ENST00000505374(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007141"(male meiosis I)|go:"GO:0007276"(gamete generation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0030154"(cell differentiation)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043186"(P granule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071546"(pi-body)|go:"GO:0071547"(piP-body)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990511"(piRNA biosynthetic process)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9NQI0|reactome:R-HSA-5601884|reactome:R-HSA-9696264 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:AUl3M8eG2a06UCy2WX+4lzRVCSc9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P02042 intact:EBI-6152703 intact:EBI-6152722|uniprotkb:Q8WXT7|uniprotkb:Q3Y5H3|ensembl:ENSP00000494708|ensembl:ENSP00000497529 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:hbd_human(display_long)|uniprotkb:Delta-globin(gene name synonym)|uniprotkb:Hemoglobin delta chain(gene name synonym)|uniprotkb:HBD(gene name)|psi-mi:HBD(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_000510.1|ensembl:ENSG00000223609(gene)|ensembl:ENST00000643122(transcript)|ensembl:ENST00000650601(transcript)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005829"(cytosol)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0031721"(hemoglobin alpha binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0072562"(blood microparticle)|go:"GO:0098869"(cellular oxidant detoxification)|interpro:IPR000971(Globin, subset)|interpro:IPR002337(Haemoglobin, beta)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|rcsb pdb:1SHR|rcsb pdb:1SI4|reactome:R-HSA-983231 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:8xPXyB/GW9LbJrqYzjTXaBgRryY9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P35637 intact:EBI-6152703 intact:EBI-400434|uniprotkb:Q9H4A8|ensembl:ENSP00000254108 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:fus_human(display_long)|uniprotkb:FUS(gene name)|psi-mi:FUS(display_short)|uniprotkb:TLS(gene name synonym)|uniprotkb:Oncogene FUS(gene name synonym)|uniprotkb:Oncogene TLS(gene name synonym)|uniprotkb:Translocated in liposarcoma protein(gene name synonym)|uniprotkb:POMp75(gene name synonym)|uniprotkb:75 kDa DNA-pairing protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_001164105.1|refseq:NP_004951.1|ensembl:ENSG00000089280(gene)|ensembl:ENST00000254108(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008380"(RNA splicing)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044327"(dendritic spine head)|go:"GO:0046872"(metal ion binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034459|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:P35637|rcsb pdb:2LA6|rcsb pdb:2LCW|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:5W3N|rcsb pdb:5XRR|rcsb pdb:5XSG|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:6BWZ|rcsb pdb:6BXV|rcsb pdb:6BZP|rcsb pdb:6G99|rcsb pdb:6GBM|rcsb pdb:6KJ1|rcsb pdb:6KJ2|rcsb pdb:6KJ3|rcsb pdb:6KJ4|rcsb pdb:6SNJ|rcsb pdb:6XFM|rcsb pdb:7CYL|reactome:R-HSA-72163|dip:DIP-29857N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:HUP4fGXQyJnm5CFTuwjTpiucZOc9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q6ZN28 intact:EBI-6152703 intact:EBI-2483498|ensembl:ENSP00000328410|ensembl:ENSP00000383185|ensembl:ENSP00000466864|uniprotkb:A8MUS5|uniprotkb:B2RNR9|uniprotkb:Q6ZQN8|uniprotkb:Q7Z5A5 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:macc1_human(display_long)|uniprotkb:MACC1(gene name)|psi-mi:MACC1(display_short)|uniprotkb:SH3 domain-containing protein 7a5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 ensembl:ENSG00000183742(gene)|ensembl:ENST00000332878(transcript)|ensembl:ENST00000400331(transcript)|ensembl:ENST00000589011(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008083"(growth factor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051781"(positive regulation of cell division)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|refseq:NP_877439.3 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:oxGaJSY19Sf/hU0oQbtMH3sIyLc9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P50991 intact:EBI-6152703 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P17844 intact:EBI-6152703 intact:EBI-351962|uniprotkb:O75681|uniprotkb:Q53Y61|uniprotkb:B4DLW8|uniprotkb:E7ETL9|uniprotkb:B5BU21|uniprotkb:D3DU32|ensembl:ENSP00000225792|ensembl:ENSP00000403085|ensembl:ENSP00000463168|ensembl:ENSP00000464337|ensembl:ENSP00000504794 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:ddx5_human(display_long)|uniprotkb:HLR1(gene name synonym)|uniprotkb:DDX5(gene name)|psi-mi:DDX5(display_short)|uniprotkb:HELR(gene name synonym)|uniprotkb:G17P1(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_004387.1|refseq:NP_001307524.1|refseq:NP_001307525.1|dip:DIP-29844N|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P17844|rcsb pdb:3FE2|rcsb pdb:4A4D|reactome:R-HSA-3899300|reactome:R-HSA-72163|reactome:R-HSA-9018519|reactome:R-HSA-9682706|reactome:R-HSA-9694686|ensembl:ENST00000225792(transcript)|ensembl:ENST00000450599(transcript)|ensembl:ENST00000577922(transcript)|ensembl:ENST00000585111(transcript)|ensembl:ENST00000676785(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009299"(mRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|ensembl:ENSG00000108654(gene) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:BlaILQg90jqkI5+DdA0k5YTCGOo9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q9P0W8 intact:EBI-6152703 intact:EBI-6152737|uniprotkb:Q5BKY5|uniprotkb:Q9P0W7|uniprotkb:Q96HF3|uniprotkb:Q8WX30|uniprotkb:Q9H0X0|ensembl:ENSP00000377176 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:spat7_human(display_long)|uniprotkb:HSD-3.1(gene name synonym)|uniprotkb:HSD3(gene name synonym)|uniprotkb:Spermatogenesis-associated protein HSD3(gene name synonym)|uniprotkb:SPATA7(gene name)|psi-mi:SPATA7(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_001035518.1|refseq:NP_060888.2|ensembl:ENSG00000042317(gene)|ensembl:ENST00000393545(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050896"(response to stimulus)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903546"(protein localization to photoreceptor outer segment)|go:"GO:1903621"(protein localization to photoreceptor connecting cilium)|interpro:IPR029357|mint:Q9P0W8 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:g+djqWT3cKjfCPnHVufeoKm9dYM9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:O00571 intact:EBI-6152703 intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P53618 intact:EBI-6152703 intact:EBI-359063|uniprotkb:Q6GTT7|uniprotkb:Q9NTK2|uniprotkb:Q9UNW7|uniprotkb:D3DQX0|ensembl:ENSP00000249923|ensembl:ENSP00000397873 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:copb_human(display_long)|uniprotkb:COPB1(gene name)|psi-mi:COPB1(display_short)|uniprotkb:COPB(gene name synonym)|uniprotkb:MSTP026(orf name)|uniprotkb:Beta-coat protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_001137533.1|refseq:NP_001137534.1|refseq:NP_057535.1|ensembl:ENSG00000129083(gene)|ensembl:ENST00000249923(transcript)|ensembl:ENST00000439561(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|mint:P53618|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-265N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:EBxh2JlK3Z8HxbZXa3fG0nOgYu89606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q13838 intact:EBI-6152703 intact:EBI-348622|uniprotkb:B0S8C0|uniprotkb:Q5STB8|uniprotkb:O43496|uniprotkb:Q0EFA1|uniprotkb:Q2L6F9|uniprotkb:Q53GL9|uniprotkb:Q5RJ64|uniprotkb:Q5RJ66|uniprotkb:Q5ST94|uniprotkb:Q5STB4|uniprotkb:Q5STB5|uniprotkb:Q5STB7|uniprotkb:Q5STU4|uniprotkb:Q5STU5|uniprotkb:Q5STU6|uniprotkb:Q5STU8|uniprotkb:Q71V76|ensembl:ENSP00000373000|ensembl:ENSP00000379475|ensembl:ENSP00000383151|ensembl:ENSP00000383152|ensembl:ENSP00000387994|ensembl:ENSP00000388880|ensembl:ENSP00000390999|ensembl:ENSP00000391463|ensembl:ENSP00000393712|ensembl:ENSP00000394160|ensembl:ENSP00000398775|ensembl:ENSP00000399030|ensembl:ENSP00000400326|ensembl:ENSP00000404695|ensembl:ENSP00000405560|ensembl:ENSP00000407419|ensembl:ENSP00000411136|ensembl:ENSP00000411853|ensembl:ENSP00000416269 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:dx39b_human(display_long)|uniprotkb:UAP56(gene name synonym)|uniprotkb:DDX39B(gene name)|psi-mi:DDX39B(display_short)|uniprotkb:DEAD box protein UAP56(gene name synonym)|uniprotkb:56 kDa U2AF65-associated protein(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p47(gene name synonym)|uniprotkb:HLA-B-associated transcript 1 protein(gene name synonym)|uniprotkb:BAT1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_004631.1|refseq:NP_542165.1|ensembl:ENSG00000198563(gene)|ensembl:ENSG00000215425(gene)|ensembl:ENSG00000225073(gene)|ensembl:ENSG00000225859(gene)|ensembl:ENSG00000229496(gene)|ensembl:ENSG00000230624(gene)|ensembl:ENSG00000235439(gene)|ensembl:ENST00000383508(transcript)|ensembl:ENST00000396172(transcript)|ensembl:ENST00000400295(transcript)|ensembl:ENST00000400296(transcript)|ensembl:ENST00000412106(transcript)|ensembl:ENST00000412330(transcript)|ensembl:ENST00000413678(transcript)|ensembl:ENST00000414440(transcript)|ensembl:ENST00000415689(transcript)|ensembl:ENST00000416863(transcript)|ensembl:ENST00000430784(transcript)|ensembl:ENST00000431360(transcript)|ensembl:ENST00000441425(transcript)|ensembl:ENST00000445218(transcript)|ensembl:ENST00000448296(transcript)|ensembl:ENST00000453138(transcript)|ensembl:ENST00000456476(transcript)|ensembl:ENST00000456666(transcript)|ensembl:ENST00000458640(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000346"(transcription export complex)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0008380"(RNA splicing)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q13838|rcsb pdb:1T5I|rcsb pdb:1T6N|rcsb pdb:1XTI|rcsb pdb:1XTJ|rcsb pdb:1XTK|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9013418 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:Cl/rf1oq31fZbLHC2foUXu9MBOE9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q13162 intact:EBI-6152703 intact:EBI-2211957|uniprotkb:Q6FHT3|ensembl:ENSP00000368646 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:prdx4_human(display_long)|uniprotkb:PRDX4(gene name)|psi-mi:PRDX4(display_short)|uniprotkb:Peroxiredoxin IV(gene name synonym)|uniprotkb:Thioredoxin peroxidase AO372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase A0372(gene name synonym)|uniprotkb:Antioxidant enzyme AOE372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_006397.1|ensembl:ENSG00000123131(gene)|ensembl:ENST00000379341(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000255"(negative regulation of male germ cell proliferation)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:Q13162|rcsb pdb:2PN8|rcsb pdb:3TJB|rcsb pdb:3TJF|rcsb pdb:3TJG|rcsb pdb:3TJJ|rcsb pdb:3TJK|rcsb pdb:3TKP|rcsb pdb:3TKQ|rcsb pdb:3TKR|rcsb pdb:3TKS|rcsb pdb:4RQX|rcsb pdb:5HQP|reactome:R-HSA-6798695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:5KWl3YuUpRDrSUxWlJS6sP7CLAs9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q56VL3 intact:EBI-6152703 intact:EBI-6152758|uniprotkb:Q8N544|uniprotkb:B4DPE7|ensembl:ENSP00000423014 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:ocad2_human(display_long)|uniprotkb:Ovarian carcinoma immunoreactive antigen-like protein(gene name synonym)|uniprotkb:OCIAD2(gene name)|psi-mi:OCIAD2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_001014446.1|refseq:NP_689611.1|refseq:NP_001273702.1|ensembl:ENSG00000145247(gene)|ensembl:ENST00000508632(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006897"(endocytosis)|go:"GO:0009617"(response to bacterium)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR009764(Ovarian carcinoma immunoreactive antigen)|interpro:IPR040187 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:z4I/nxTOVnbJ/RZhY11VYbBas0g9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P68104 intact:EBI-6152703 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P62258 intact:EBI-6152703 intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q6PI48 intact:EBI-6152703 intact:EBI-3917045|ensembl:ENSP00000497569 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:sydm_human(display_long)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:DARS2(gene name)|psi-mi:DARS2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_060592.2|ensembl:ENSG00000117593(gene)|ensembl:ENST00000649689(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043039"(tRNA aminoacylation)|go:"GO:0050560"("aspartate-tRNA(Asn) ligase activity")|go:"GO:0070145"(mitochondrial asparaginyl-tRNA aminoacylation)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004115(GAD)|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004524(Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR029351|rcsb pdb:4AH6|reactome:R-HSA-379726|go:"GO:0005759"(mitochondrial matrix) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:6tNhPqrlJ5dCXoDIgUjcUB/gA7s9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P22061 intact:EBI-6152703 intact:EBI-353343|uniprotkb:Q14661|uniprotkb:Q16556|uniprotkb:Q5VYC1|uniprotkb:Q5VYC2|uniprotkb:Q93061|uniprotkb:Q96II9|uniprotkb:Q99625|uniprotkb:Q9BQV7|uniprotkb:Q9BQV8|uniprotkb:Q9NP03|uniprotkb:A8K109|intact:EBI-2551555|uniprotkb:J3KP72|ensembl:ENSP00000356348|ensembl:ENSP00000420813 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:pimt_human(display_long)|uniprotkb:PCMT1(gene name)|psi-mi:PCMT1(display_short)|uniprotkb:Protein-beta-aspartate methyltransferase(gene name synonym)|uniprotkb:Protein L-isoaspartyl/D-aspartyl methyltransferase(gene name synonym)|uniprotkb:L-isoaspartyl protein carboxyl methyltransferase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_001238978.1|refseq:NP_001238982.1|ensembl:ENSG00000120265(gene)|ensembl:ENST00000367378(transcript)|ensembl:ENST00000464889(transcript)|go:"GO:0004719"("protein-L-isoaspartate (D-aspartate) O-methyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0030091"(protein repair)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000682("Protein-L-isoaspartate(D-aspartate) O-methyltransferase")|interpro:IPR029063|mint:P22061|rcsb pdb:1I1N|rcsb pdb:1KR5|reactome:R-HSA-5676934|refseq:NP_005380.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:wfsjVloc3sqDMXlvFAXQI6Fjilw9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P08865 intact:EBI-6152703 intact:EBI-354112|uniprotkb:Q6NSD1|uniprotkb:Q6NXQ8|uniprotkb:Q86VC0|uniprotkb:P11085|uniprotkb:P12030|uniprotkb:Q16471|uniprotkb:Q6IPD1|uniprotkb:Q6IPD2|ensembl:ENSP00000346067 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:rssa_human(display_long)|uniprotkb:RPSA(gene name)|psi-mi:RPSA(display_short)|uniprotkb:LAMBR(gene name synonym)|uniprotkb:LAMR1(gene name synonym)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:Colon carcinoma laminin-binding protein(gene name synonym)|uniprotkb:NEM/1CHD4(gene name synonym)|uniprotkb:Multidrug resistance-associated protein MGr1-Ag(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_002286.2|refseq:NP_001291217.1|dip:DIP-32878N|ensembl:ENSG00000168028(gene)|ensembl:ENST00000301821(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0007155"(cell adhesion)|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZOJ|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|go:"GO:0043236"(laminin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P08865|rcsb pdb:3BCH|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:Jpv3I3G5C297fHfNwIqyB9Pf8/A9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q96M02 intact:EBI-6152703 intact:EBI-6152728|uniprotkb:Q8WU75|uniprotkb:Q5JRP6|uniprotkb:Q5T023|uniprotkb:B9EIQ9|uniprotkb:Q8NCV5|ensembl:ENSP00000284694 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:cj090_human(display_long)|uniprotkb:FATS(gene name synonym)|uniprotkb:Fragile-site associated tumor suppressor homolog(gene name synonym)|uniprotkb:C10orf90(gene name)|psi-mi:C10orf90(display_short)|uniprotkb:Centrosomal protein C10orf90(gene name synonym)|uniprotkb:E2/E3 hybrid ubiquitin-protein ligase FATS(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_001004298.2|ensembl:ENSG00000154493(gene)|ensembl:ENST00000284694(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008017"(microtubule binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0050821"(protein stabilization)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR029299|interpro:IPR029561|interpro:IPR041179 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:naG3fB3XXfhnbCczHW8FaDcX42c9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q13263 intact:EBI-6152703 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P52597 intact:EBI-6152703 intact:EBI-352986|ensembl:ENSP00000338477|ensembl:ENSP00000349573|ensembl:ENSP00000400433|ensembl:ENSP00000438061|ensembl:ENSP00000507787|ensembl:ENSP00000348345|uniprotkb:Q5T0N2|uniprotkb:Q96AU2|uniprotkb:B3KM84 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:hnrpf_human(display_long)|uniprotkb:HNRNPF(gene name)|psi-mi:HNRNPF(display_short)|uniprotkb:HNRPF(gene name synonym)|uniprotkb:Nucleolin-like protein mcs94-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P52597|rcsb pdb:2HGL|rcsb pdb:2HGM|rcsb pdb:2HGN|rcsb pdb:2KFY|rcsb pdb:2KG0|rcsb pdb:2KG1|rcsb pdb:3TFY|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensembl:ENSG00000169813(gene)|ensembl:ENST00000337970(transcript)|ensembl:ENST00000356053(transcript)|ensembl:ENST00000357065(transcript)|ensembl:ENST00000443950(transcript)|ensembl:ENST00000544000(transcript)|ensembl:ENST00000682386(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001091674.1|refseq:NP_001091675.1|refseq:NP_001091676.1|refseq:NP_001091677.1|refseq:NP_001091678.1|refseq:NP_004957.1|dip:DIP-33145N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:pblzpldZOa5vlZ+zGQY9qyWCxaw9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P07900 intact:EBI-6152703 intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|ensembl:ENSP00000216281|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 go:"GO:0009409"(response to cold)|go:"GO:0016020"(membrane)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|ensembl:ENST00000216281(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000080824(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043335"(protein unfolding)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1UY8|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2BYH|rcsb pdb:2VCJ|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3B24|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5LO1|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6CYH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7LSZ|rcsb pdb:7LT0|reactome:R-HSA-1227986|reactome:R-HSA-1236382|rcsb pdb:6TN4|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9665233|reactome:R-HSA-9664565|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3K99|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:3T0H|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:4YKZ|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|refseq:NP_001017963.2|refseq:NP_005339.3|dip:DIP-27595N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q9UKM7 intact:EBI-6152703 intact:EBI-6152715|uniprotkb:Q9BRS9|uniprotkb:Q9Y5K7|uniprotkb:Q5VSG3|ensembl:ENSP00000360645 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:ma1b1_human(display_long)|uniprotkb:ER alpha-1,2-mannosidase(gene name synonym)|uniprotkb:ER mannosidase 1(gene name synonym)|uniprotkb:Man9GlcNAc2-specific-processing alpha-mannosidase(gene name synonym)|uniprotkb:Mannosidase alpha class 1B member 1(gene name synonym)|uniprotkb:UNQ747/PRO1477(orf name)|uniprotkb:MAN1B1(gene name)|psi-mi:MAN1B1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_057303.2|ensembl:ENSG00000177239(gene)|ensembl:ENST00000371589(transcript)|go:"GO:0004571"(mannosyl-oligosaccharide 1,2-alpha-mannosidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006491"(N-glycan processing)|go:"GO:0009311"(oligosaccharide metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036508"(protein alpha-1,2-demannosylation)|go:"GO:0036509"(trimming of terminal mannose on B branch)|go:"GO:0036510"(trimming of terminal mannose on C branch)|go:"GO:0036511"(trimming of first mannose on A branch)|go:"GO:0036512"(trimming of second mannose on A branch)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|go:"GO:1904382"(mannose trimming involved in glycoprotein ERAD pathway)|interpro:IPR001382(Glycoside hydrolase, family 47)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR036026|rcsb pdb:1FMI|rcsb pdb:1FO2|rcsb pdb:1FO3|rcsb pdb:1X9D|rcsb pdb:5KIJ|rcsb pdb:5KK7|reactome:R-HSA-4793950|reactome:R-HSA-901032|reactome:R-HSA-9694548 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:BWs6sG0JMvsFWi0+Wl03jQv3hOk9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P82979 intact:EBI-6152703 intact:EBI-347495|uniprotkb:Q9P066|uniprotkb:A8K393|ensembl:ENSP00000337632|ensembl:ENSP00000449409 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:sarnp_human(display_long)|uniprotkb:HSPC316(orf name)|uniprotkb:Cytokine-induced protein of 29 kDa(gene name synonym)|uniprotkb:SARNP(gene name)|psi-mi:SARNP(display_short)|uniprotkb:Proliferation-associated cytokine-inducible protein CIP29(gene name synonym)|uniprotkb:HCC1(gene name synonym)|uniprotkb:Nuclear protein Hcc-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_149073.1|ensembl:ENSG00000205323(gene)|ensembl:ENST00000336133(transcript)|ensembl:ENST00000546604(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006417"(regulation of translation)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR036361|mint:P82979|rcsb pdb:2DO1|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR003034(DNA-binding SAP) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:O/j7XYd9K3eQu1JS58FSsEyPRpE9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P68371 intact:EBI-6152703 intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q7L1T6 intact:EBI-6152703 intact:EBI-6152707|uniprotkb:Q5TGI9|uniprotkb:Q9UHI9|uniprotkb:B1AEM2|uniprotkb:Q9NUE4|ensembl:ENSP00000358695 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:nb5r4_human(display_long)|uniprotkb:Flavohemoprotein b5/b5R(gene name synonym)|uniprotkb:N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein(gene name synonym)|uniprotkb:NCB5OR(gene name synonym)|uniprotkb:cb5/cb5R(gene name synonym)|uniprotkb:CYB5R4(gene name)|psi-mi:CYB5R4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 ensembl:ENSG00000065615(gene)|refseq:NP_057314.2|ensembl:ENST00000369681(transcript)|go:"GO:0003032"(detection of oxygen)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016653"("oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor")|go:"GO:0020037"(heme binding)|go:"GO:0030073"(insulin secretion)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR001199(Cytochrome b5)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR007052(CS domain)|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR017927|interpro:IPR017938|interpro:IPR018506|interpro:IPR036400|interpro:IPR037908|interpro:IPR039261|rcsb pdb:3LF5|rcsb pdb:6MV1|rcsb pdb:6MV2|reactome:R-HSA-1237044 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:XLICcTbtqPSVcP/lKxcSMp7H0XM9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P31689 intact:EBI-6152703 intact:EBI-347834|ensembl:ENSP00000369127|uniprotkb:Q5T7Q0|uniprotkb:Q86TL9 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:dnja1_human(display_long)|uniprotkb:DNAJA1(gene name)|psi-mi:DNAJA1(display_short)|uniprotkb:DNAJ2(gene name synonym)|uniprotkb:HDJ2(gene name synonym)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:HSPF4(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Human DnaJ protein 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:HSDJ(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 ensembl:ENSG00000086061(gene)|ensembl:ENST00000330899(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P31689|rcsb pdb:2LO1|rcsb pdb:2M6Y|reactome:R-HSA-3371497|rcsb pdb:6E8M|refseq:NP_001530.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:YEHeLHYaG2ON2gwuFfqt9Le1Drg9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q8IW75 intact:EBI-6152703 intact:EBI-6152746|ensembl:ENSP00000342109|ensembl:ENSP00000451738|ensembl:ENSP00000503935 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:spa12_human(display_long)|uniprotkb:OL-64(gene name synonym)|uniprotkb:Visceral adipose tissue-derived serine protease inhibitor(gene name synonym)|uniprotkb:Visceral adipose-specific serpin(gene name synonym)|uniprotkb:SERPINA12(gene name)|psi-mi:SERPINA12(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_001291390.1|refseq:XP_011534753.1|refseq:XP_011534754.1|refseq:XP_011534755.1|refseq:XP_011534756.1|refseq:NP_776249.1|refseq:XP_016876478.1|refseq:XP_016876479.1|ensembl:ENSG00000165953(gene)|ensembl:ENST00000341228(transcript)|ensembl:ENST00000556881(transcript)|ensembl:ENST00000677451(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0010951"(negative regulation of endopeptidase activity)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:4IF8|rcsb pdb:4Y3K|rcsb pdb:4Y40|rcsb pdb:5EI0 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:+5f/WOqyIiG/Xre5SrhaX/GWS4g9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q71U36 intact:EBI-6152703 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:O75116 intact:EBI-6152703 intact:EBI-366288|uniprotkb:Q9UQN5|ensembl:ENSP00000317985|uniprotkb:Q53QZ0|uniprotkb:Q53SJ7 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:rock2_human(display_long)|uniprotkb:ROCK2(gene name)|psi-mi:ROCK2(display_short)|uniprotkb:KIAA0619(gene name synonym)|uniprotkb:Rho-associated, coiled-coil-containing protein kinase II(gene name synonym)|uniprotkb:Rho-associated, coiled-coil-containing protein kinase 2(gene name synonym)|uniprotkb:p164 ROCK-2(gene name synonym)|uniprotkb:Rho kinase 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1903347"(negative regulation of bicellular tight junction assembly)|go:"GO:1905145"(cellular response to acetylcholine)|go:"GO:1905205"(positive regulation of connective tissue replacement)|go:"GO:1990776"(response to angiotensin)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015008(Rho Binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020684|interpro:IPR037311|mint:O75116|rcsb pdb:4L6Q|rcsb pdb:4WOT|rcsb pdb:5U7Q|rcsb pdb:5U7R|rcsb pdb:6ED6|rcsb pdb:6P5M|rcsb pdb:6P5P|rcsb pdb:7JNT|rcsb pdb:7JOV|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5627117|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013407|reactome:R-HSA-9013422|reactome:R-HSA-9679191|refseq:NP_004841.2|ensembl:ENSG00000134318(gene)|ensembl:ENST00000315872(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|refseq:NP_001308572.1|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031644"(regulation of nervous system process)|go:"GO:0032723"(positive regulation of connective tissue growth factor production)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035509"(negative regulation of myosin-light-chain-phosphatase activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:0071394"(cellular response to testosterone stimulus)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:0072518"(Rho-dependent protein serine/threonine kinase activity)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090271"(positive regulation of fibroblast growth factor production)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110061"(regulation of angiotensin-activated signaling pathway)|go:"GO:0150033"(negative regulation of protein localization to lysosome)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902961"(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1902993"(positive regulation of amyloid precursor protein catabolic process) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:iCgqC5U/DXAzOEq6edMtL6ncK7U9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P55072 intact:EBI-6152703 intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:Q52LJ0 intact:EBI-6152703 intact:EBI-1043130|uniprotkb:Q8N935|ensembl:ENSP00000380734|uniprotkb:A8MUW5 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:fa98b_human(display_long)|uniprotkb:FAM98B(gene name)|psi-mi:FAM98B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 go:"GO:0005737"(cytoplasm)|go:"GO:0006479"(protein methylation)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0072669"(tRNA-splicing ligase complex)|interpro:IPR018797|reactome:R-HSA-6784531|ensembl:ENSG00000171262(gene)|ensembl:ENST00000397609(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|refseq:NP_775882.2|dip:DIP-50585N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:gi2tyKR3C5LWwtGV+7NzzsNETII9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P10809 intact:EBI-6152703 intact:EBI-352528|ensembl:ENSP00000340019|ensembl:ENSP00000373620|ensembl:ENSP00000396460|ensembl:ENSP00000402478|ensembl:ENSP00000412227|ensembl:ENSP00000412717|ensembl:ENSP00000414446|ensembl:ENSP00000503139|ensembl:ENSP00000503894|uniprotkb:Q38L19|uniprotkb:B2R5M6|uniprotkb:Q9UCR6|uniprotkb:B7Z712 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:ch60_human(display_long)|uniprotkb:HSPD1(gene name)|psi-mi:HSPD1(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:P60 lymphocyte protein(gene name synonym)|uniprotkb:HuCHA60(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_002147.2|refseq:NP_955472.1|ensembl:ENSG00000144381(gene)|ensembl:ENST00000345042(transcript)|ensembl:ENST00000388968(transcript)|ensembl:ENST00000418022(transcript)|ensembl:ENST00000426480(transcript)|ensembl:ENST00000428204(transcript)|ensembl:ENST00000439605(transcript)|ensembl:ENST00000452200(transcript)|ensembl:ENST00000677913(transcript)|ensembl:ENST00000678761(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051604"(protein maturation)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P10809|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|rcsb pdb:7AZP|reactome:R-HSA-1268020|reactome:R-HSA-8869496|dip:DIP-58N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:syB2vt66Cpr2mJROfbxoPevoiRE9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:P33176 intact:EBI-6152703 intact:EBI-355878|uniprotkb:A0AVB2|uniprotkb:Q5VZ85|ensembl:ENSP00000307078 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:kinh_human(display_long)|uniprotkb:KIF5B(gene name)|psi-mi:KIF5B(display_short)|uniprotkb:KNS(gene name synonym)|uniprotkb:KNS1(gene name synonym)|uniprotkb:Ubiquitous kinesin heavy chain(gene name synonym)|uniprotkb:Conventional kinesin heavy chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_004512.1|ensembl:ENSG00000170759(gene)|ensembl:ENST00000302418(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007028"(cytoplasm organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016020"(membrane)|go:"GO:0021766"(hippocampus development)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031982"(vesicle)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032418"(lysosome localization)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045296"(cadherin binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099609"(microtubule lateral binding)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905152"(positive regulation of voltage-gated sodium channel activity)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:P33176|rcsb pdb:1BG2|rcsb pdb:1MKJ|rcsb pdb:2P4N|rcsb pdb:3J8X|rcsb pdb:3J8Y|rcsb pdb:4HNA|rcsb pdb:4LNU|rcsb pdb:5LT0|rcsb pdb:5LT1|rcsb pdb:5LT2|rcsb pdb:5LT3|rcsb pdb:5LT4|rcsb pdb:6OJQ|reactome:R-HSA-2132295|reactome:R-HSA-264876|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-983189|dip:DIP-29244N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:2UUVZBn5EAd0xBA5IZDPWHX9i7U9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8JPQ9 uniprotkb:O15523 intact:EBI-6152703 intact:EBI-2462220|uniprotkb:Q8IYV7|uniprotkb:B4DK29|uniprotkb:B4DXX7|ensembl:ENSP00000336725|ensembl:ENSP00000353284 psi-mi:nss_bunl8(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short) psi-mi:ddx3y_human(display_long)|uniprotkb:DDX3Y(gene name)|psi-mi:DDX3Y(display_short)|uniprotkb:DBY(gene name synonym)|uniprotkb:DEAD box protein 3, Y-chromosomal(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:796210(bunl8)|taxid:796210("Bunyavirus La Crosse (isolate Human/United States/L78/1978)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159460|imex:IM-17331-64 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0039657"(suppression by virus of host gene expression)|interpro:IPR000797(Bunyavirus non-structural protein NS-s)|refseq:NP_671971.1 refseq:NP_001116137.1|refseq:NP_004651.2|refseq:NP_001289481.1|ensembl:ENSG00000067048(gene)|ensembl:ENST00000336079(transcript)|ensembl:ENST00000360160(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007276"(gamete generation)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0043186"(P granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O15523 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:vHAnCzz8j1XJNtlVVo1/Vf1DJro796210 rogid:dYhBr9Igq5eMq9U8g+c30nfdaKo9606 intact-crc:2B2A189360757559|rigid:VwHQiRyd0O+ppgvFHybbBMGVKK8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2A1D8 uniprotkb:Q9BQE3 intact:EBI-6153032 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:h2a1d8_muhv1(display_long)|uniprotkb:M84(gene name)|psi-mi:M84(display_short) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10366(muhv1)|taxid:10366(Murid herpesvirus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159715|imex:IM-17331-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008649(Betaherpesvirus UL8283, N-terminal) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:ubPAqzGIkF38ZA9SHdKo3rcOBHQ10366 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:E3990E079AA1679E|rigid:173tdA9dYsTAuCHNu46EakfblUg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2A1D8 uniprotkb:O95816 intact:EBI-6153032 intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407 psi-mi:h2a1d8_muhv1(display_long)|uniprotkb:M84(gene name)|psi-mi:M84(display_short) psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10366(muhv1)|taxid:10366(Murid herpesvirus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159715|imex:IM-17331-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008649(Betaherpesvirus UL8283, N-terminal) refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:ubPAqzGIkF38ZA9SHdKo3rcOBHQ10366 rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606 intact-crc:E3990E079AA1679E|rigid:173tdA9dYsTAuCHNu46EakfblUg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2A1D8 uniprotkb:Q71UM5 intact:EBI-6153032 intact:EBI-355126|uniprotkb:Q9BTJ1|ensembl:ENSP00000331019 psi-mi:h2a1d8_muhv1(display_long)|uniprotkb:M84(gene name)|psi-mi:M84(display_short) psi-mi:rs27l_human(display_long)|uniprotkb:RPS27L(gene name)|psi-mi:RPS27L(display_short)|uniprotkb:Small ribosomal subunit protein eS27-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10366(muhv1)|taxid:10366(Murid herpesvirus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159715|imex:IM-17331-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008649(Betaherpesvirus UL8283, N-terminal) refseq:NP_057004.1|ensembl:ENSG00000185088(gene)|ensembl:ENST00000330964(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0006412"(translation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008494"(translation activator activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:Q71UM5|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:ubPAqzGIkF38ZA9SHdKo3rcOBHQ10366 rogid:OVIAlDF6dN3DxLZgQFrFl8r0Z0I9606 intact-crc:E3990E079AA1679E|rigid:173tdA9dYsTAuCHNu46EakfblUg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2A1D8 uniprotkb:Q3ZCQ8 intact:EBI-6153032 intact:EBI-355175|uniprotkb:Q6QA00|uniprotkb:Q96FJ5|uniprotkb:Q96GY2|uniprotkb:Q9H370|intact:EBI-2554785|uniprotkb:Q330K1|ensembl:ENSP00000475531 psi-mi:h2a1d8_muhv1(display_long)|uniprotkb:M84(gene name)|psi-mi:M84(display_short) psi-mi:tim50_human(display_long)|uniprotkb:TIMM50(gene name)|psi-mi:TIMM50(display_short)|uniprotkb:TIM50(gene name synonym)|uniprotkb:PRO1512(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10366(muhv1)|taxid:10366(Murid herpesvirus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159715|imex:IM-17331-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008649(Betaherpesvirus UL8283, N-terminal) refseq:NP_001001563.1|ensembl:ENSG00000105197(gene)|ensembl:ENST00000607714(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003723"(RNA binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005134"(interleukin-2 receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005744"(TIM23 mitochondrial import inner membrane translocase complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007006"(mitochondrial membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR004274(NLI interacting factor)|interpro:IPR023214|interpro:IPR027111|interpro:IPR036412|mint:Q3ZCQ8|reactome:R-HSA-1268020|refseq:NP_001316488.1|dip:DIP-34058N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:ubPAqzGIkF38ZA9SHdKo3rcOBHQ10366 rogid:fOPV33h12YhAq9jj0bVno01Q+6g9606 intact-crc:E3990E079AA1679E|rigid:173tdA9dYsTAuCHNu46EakfblUg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2A1D8 uniprotkb:P49411 intact:EBI-6153032 intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439 psi-mi:h2a1d8_muhv1(display_long)|uniprotkb:M84(gene name)|psi-mi:M84(display_short) psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10366(muhv1)|taxid:10366(Murid herpesvirus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159715|imex:IM-17331-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008649(Betaherpesvirus UL8283, N-terminal) refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:ubPAqzGIkF38ZA9SHdKo3rcOBHQ10366 rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606 intact-crc:E3990E079AA1679E|rigid:173tdA9dYsTAuCHNu46EakfblUg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2A1D8 uniprotkb:P12036 intact:EBI-6153032 intact:EBI-2880271|uniprotkb:Q9UQ14|uniprotkb:Q9UJS7|uniprotkb:Q96HF8|uniprotkb:B4DYY4|ensembl:ENSP00000311997 psi-mi:h2a1d8_muhv1(display_long)|uniprotkb:M84(gene name)|psi-mi:M84(display_short) psi-mi:nfh_human(display_long)|uniprotkb:NEFH(gene name)|psi-mi:NEFH(display_short)|uniprotkb:KIAA0845(gene name synonym)|uniprotkb:NFH(gene name synonym)|uniprotkb:200 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament triplet H protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10366(muhv1)|taxid:10366(Murid herpesvirus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159715|imex:IM-17331-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008649(Betaherpesvirus UL8283, N-terminal) refseq:NP_066554.2|ensembl:ENSG00000100285(gene)|ensembl:ENST00000310624(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005883"(neurofilament)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0061564"(axon development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR010790(Protein of unknown function DUF1388)|interpro:IPR018039|interpro:IPR033183|interpro:IPR039008|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:ubPAqzGIkF38ZA9SHdKo3rcOBHQ10366 rogid:TXMrn6SWBHIYQY1loZfVvMo9PtU9606 intact-crc:E3990E079AA1679E|rigid:173tdA9dYsTAuCHNu46EakfblUg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2A1D8 uniprotkb:P07437 intact:EBI-6153032 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:h2a1d8_muhv1(display_long)|uniprotkb:M84(gene name)|psi-mi:M84(display_short) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10366(muhv1)|taxid:10366(Murid herpesvirus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159715|imex:IM-17331-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008649(Betaherpesvirus UL8283, N-terminal) refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:ubPAqzGIkF38ZA9SHdKo3rcOBHQ10366 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:E3990E079AA1679E|rigid:173tdA9dYsTAuCHNu46EakfblUg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2A1D8 uniprotkb:P42677 intact:EBI-6153032 intact:EBI-356336|ensembl:ENSP00000499044|uniprotkb:Q5T4L6 psi-mi:h2a1d8_muhv1(display_long)|uniprotkb:M84(gene name)|psi-mi:M84(display_short) psi-mi:rs27_human(display_long)|uniprotkb:RPS27(gene name)|psi-mi:RPS27(display_short)|uniprotkb:MPS1(gene name synonym)|uniprotkb:Metallopan-stimulin 1(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS27(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10366(muhv1)|taxid:10366(Murid herpesvirus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159715|imex:IM-17331-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008649(Betaherpesvirus UL8283, N-terminal) refseq:NP_001021.1|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|ensembl:ENSG00000177954(gene)|ensembl:ENST00000651669(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:P42677|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-141444|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-2500257|rcsb pdb:6OM7|reactome:R-HSA-5663220|reactome:R-HSA-6791226|reactome:R-HSA-68877|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-9648025|reactome:R-HSA-975956|reactome:R-HSA-975957|dip:DIP-44182N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:ubPAqzGIkF38ZA9SHdKo3rcOBHQ10366 rogid:OA5IWAJDBpY5FFdVnun7Sq/jI7g9606 intact-crc:E3990E079AA1679E|rigid:173tdA9dYsTAuCHNu46EakfblUg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2A1D8 uniprotkb:Q71U36 intact:EBI-6153032 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:h2a1d8_muhv1(display_long)|uniprotkb:M84(gene name)|psi-mi:M84(display_short) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10366(muhv1)|taxid:10366(Murid herpesvirus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159715|imex:IM-17331-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008649(Betaherpesvirus UL8283, N-terminal) refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:ubPAqzGIkF38ZA9SHdKo3rcOBHQ10366 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 intact-crc:E3990E079AA1679E|rigid:173tdA9dYsTAuCHNu46EakfblUg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:H2A1D8 uniprotkb:O14654 intact:EBI-6153032 intact:EBI-356594|ensembl:ENSP00000505547 psi-mi:h2a1d8_muhv1(display_long)|uniprotkb:M84(gene name)|psi-mi:M84(display_short) psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10366(muhv1)|taxid:10366(Murid herpesvirus 1) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159715|imex:IM-17331-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR008649(Betaherpesvirus UL8283, N-terminal) ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2015/09/23 rogid:ubPAqzGIkF38ZA9SHdKo3rcOBHQ10366 rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606 intact-crc:E3990E079AA1679E|rigid:173tdA9dYsTAuCHNu46EakfblUg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C765 uniprotkb:Q02539 intact:EBI-6153073 intact:EBI-932603|uniprotkb:Q3MJ34|ensembl:ENSP00000244573 psi-mi:v_ndvb1(display_long)|uniprotkb:V(gene name)|psi-mi:V(display_short) psi-mi:h11_human(display_long)|uniprotkb:H1-1(gene name)|psi-mi:H1-1(display_short)|uniprotkb:H1F1(gene name synonym)|uniprotkb:HIST1H1A(gene name synonym)|uniprotkb:Histone H1a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:652953(ndv)|taxid:652953("Newcastle disease virus (strain Chicken/United States/B1/48)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159751|imex:IM-17331-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR025909|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_005316.1|ensembl:ENSG00000124610(gene)|ensembl:ENST00000244573(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q02539|reactome:R-HSA-140342|reactome:R-HSA-2559584 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:+1FeCtb4I1gsGzOn9JPcJQIc+Lg652953 rogid:4u8P8jFM3onWx43+SxL320urjhk9606 intact-crc:088C09F80F6465FE|rigid:lVgTEfPqxxlsl+30jR2+QPX4cts false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C765 uniprotkb:Q9NPH2 intact:EBI-6153073 intact:EBI-720563|intact:EBI-1050340|uniprotkb:Q7Z525|uniprotkb:Q9BT65|uniprotkb:Q9H2Y2|uniprotkb:Q9NSU0|uniprotkb:Q9NVW7|uniprotkb:Q6NXT5|uniprotkb:B3KRT1|uniprotkb:G5E9U0|ensembl:ENSP00000337746 psi-mi:v_ndvb1(display_long)|uniprotkb:V(gene name)|psi-mi:V(display_short) psi-mi:ino1_human(display_long)|uniprotkb:INO1(gene name synonym)|uniprotkb:ISYNA1(gene name)|psi-mi:ISYNA1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase A1(gene name synonym)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:652953(ndv)|taxid:652953("Newcastle disease virus (strain Chicken/United States/B1/48)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159751|imex:IM-17331-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR025909|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_001164409.1|refseq:NP_057452.1|refseq:NP_001240318.1|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|reactome:R-HSA-1855183|ensembl:ENSG00000105655(gene)|ensembl:ENST00000338128(transcript)|go:"GO:0004512"(inositol-3-phosphate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:+1FeCtb4I1gsGzOn9JPcJQIc+Lg652953 rogid:46Ryo/iaI6hmbkuetMsJSyrm3FU9606 intact-crc:088C09F80F6465FE|rigid:lVgTEfPqxxlsl+30jR2+QPX4cts false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C765 uniprotkb:P07437 intact:EBI-6153073 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:v_ndvb1(display_long)|uniprotkb:V(gene name)|psi-mi:V(display_short) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:652953(ndv)|taxid:652953("Newcastle disease virus (strain Chicken/United States/B1/48)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159751|imex:IM-17331-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR025909|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:+1FeCtb4I1gsGzOn9JPcJQIc+Lg652953 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:088C09F80F6465FE|rigid:lVgTEfPqxxlsl+30jR2+QPX4cts false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C765 uniprotkb:Q9BQE3 intact:EBI-6153073 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:v_ndvb1(display_long)|uniprotkb:V(gene name)|psi-mi:V(display_short) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:652953(ndv)|taxid:652953("Newcastle disease virus (strain Chicken/United States/B1/48)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159751|imex:IM-17331-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR025909|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:+1FeCtb4I1gsGzOn9JPcJQIc+Lg652953 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:088C09F80F6465FE|rigid:lVgTEfPqxxlsl+30jR2+QPX4cts false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C765 uniprotkb:P68371 intact:EBI-6153073 intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289 psi-mi:v_ndvb1(display_long)|uniprotkb:V(gene name)|psi-mi:V(display_short) psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:652953(ndv)|taxid:652953("Newcastle disease virus (strain Chicken/United States/B1/48)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159751|imex:IM-17331-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR025909|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:+1FeCtb4I1gsGzOn9JPcJQIc+Lg652953 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606 intact-crc:088C09F80F6465FE|rigid:lVgTEfPqxxlsl+30jR2+QPX4cts false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C765 uniprotkb:Q9BYX4 intact:EBI-6153073 intact:EBI-6115771|uniprotkb:Q2NKL6|uniprotkb:Q6DC96|uniprotkb:Q86X56|uniprotkb:Q96MX8|uniprotkb:Q9H3G6|ensembl:ENSP00000497271 psi-mi:v_ndvb1(display_long)|uniprotkb:V(gene name)|psi-mi:V(display_short) psi-mi:ifih1_human(display_long)|uniprotkb:Helicase with 2 CARD domains(gene name synonym)|uniprotkb:Interferon-induced with helicase C domain protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 5(gene name synonym)|uniprotkb:Murabutide down-regulated protein(gene name synonym)|uniprotkb:RNA helicase-DEAD box protein 116(gene name synonym)|uniprotkb:RIG-I-like receptor 2(gene name synonym)|uniprotkb:IFIH1(gene name)|psi-mi:IFIH1(display_short)|uniprotkb:MDA5(gene name synonym)|uniprotkb:RH116(gene name synonym)|uniprotkb:Clinically amyopathic dermatomyositis autoantigen 140 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:652953(ndv)|taxid:652953("Newcastle disease virus (strain Chicken/United States/B1/48)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159751|imex:IM-17331-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR025909|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_071451.2|dip:DIP-42607N|ensembl:ENSG00000115267(gene)|ensembl:ENST00000649979(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009597"(detection of virus)|go:"GO:0009615"(response to virus)|go:"GO:0016925"(protein sumoylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034344"(regulation of type III interferon production)|go:"GO:0039528"(cytoplasmic pattern recognition receptor signaling pathway in response to virus)|go:"GO:0039530"(MDA-5 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR011029(DEATH-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR021673|interpro:IPR027417|interpro:IPR031964|interpro:IPR038557|interpro:IPR041204|rcsb pdb:2RQB|rcsb pdb:3B6E|rcsb pdb:3GA3|rcsb pdb:4GL2|rcsb pdb:7JL0|rcsb pdb:7JL2|reactome:R-HSA-168928|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:+1FeCtb4I1gsGzOn9JPcJQIc+Lg652953 rogid:d+r0DiHIxi32jKF7uOTENK3r/qQ9606 intact-crc:088C09F80F6465FE|rigid:lVgTEfPqxxlsl+30jR2+QPX4cts false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C765 uniprotkb:P22492 intact:EBI-6153073 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 psi-mi:v_ndvb1(display_long)|uniprotkb:V(gene name)|psi-mi:V(display_short) psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:652953(ndv)|taxid:652953("Newcastle disease virus (strain Chicken/United States/B1/48)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159751|imex:IM-17331-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR025909|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:+1FeCtb4I1gsGzOn9JPcJQIc+Lg652953 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 intact-crc:088C09F80F6465FE|rigid:lVgTEfPqxxlsl+30jR2+QPX4cts false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C765 uniprotkb:Q00325 intact:EBI-6153073 intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34 psi-mi:v_ndvb1(display_long)|uniprotkb:V(gene name)|psi-mi:V(display_short) psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:652953(ndv)|taxid:652953("Newcastle disease virus (strain Chicken/United States/B1/48)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159751|imex:IM-17331-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR025909|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325 - - crc64:78714C85931B22D5 figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:+1FeCtb4I1gsGzOn9JPcJQIc+Lg652953 rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606 intact-crc:088C09F80F6465FE|rigid:lVgTEfPqxxlsl+30jR2+QPX4cts false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C765 uniprotkb:P62805 intact:EBI-6153073 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:v_ndvb1(display_long)|uniprotkb:V(gene name)|psi-mi:V(display_short) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:652953(ndv)|taxid:652953("Newcastle disease virus (strain Chicken/United States/B1/48)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159751|imex:IM-17331-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR025909|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:+1FeCtb4I1gsGzOn9JPcJQIc+Lg652953 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:088C09F80F6465FE|rigid:lVgTEfPqxxlsl+30jR2+QPX4cts false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C765 uniprotkb:Q71U36 intact:EBI-6153073 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:v_ndvb1(display_long)|uniprotkb:V(gene name)|psi-mi:V(display_short) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:652953(ndv)|taxid:652953("Newcastle disease virus (strain Chicken/United States/B1/48)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159751|imex:IM-17331-66 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR024279|interpro:IPR025909|go:"GO:0019050"(suppression by virus of host apoptotic process)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039554"(suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046872"(metal ion binding) refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:+1FeCtb4I1gsGzOn9JPcJQIc+Lg652953 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 intact-crc:088C09F80F6465FE|rigid:lVgTEfPqxxlsl+30jR2+QPX4cts false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P07939 uniprotkb:Q6PKG0 intact:EBI-6153113 intact:EBI-1052114|uniprotkb:O94836|uniprotkb:Q8N4M2|uniprotkb:Q8NB73|uniprotkb:Q9UFD7|ensembl:ENSP00000428589 psi-mi:sigm3_reovl(display_long)|uniprotkb:S4(gene name)|psi-mi:S4(display_short) psi-mi:larp1_human(display_long)|uniprotkb:La ribonucleoprotein domain family member 1(gene name synonym)|uniprotkb:LARP1(gene name)|psi-mi:LARP1(display_short)|uniprotkb:KIAA0731(gene name synonym)|uniprotkb:LARP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159787|imex:IM-17331-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000153(Outer capsid sigma 3, reoviral)|interpro:IPR023634|rcsb pdb:1JMU|rcsb pdb:2CSE|rcsb pdb:6XF8|rcsb pdb:6ZTY|rcsb pdb:6ZTZ|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006417"(regulation of translation)|go:"GO:0019058"(viral life cycle)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039624"(viral outer capsid)|go:"GO:0046872"(metal ion binding) refseq:NP_056130.2|ensembl:ENST00000336314|ensembl:ENSP00000336721|ensembl:ENSP00000428589|refseq:XP_005268461.1|ensembl:ENSG00000155506(gene)|ensembl:ENST00000518297(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008494"(translation activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031929"(TOR signaling)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR006607(Protein of unknown function DM15)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|mint:Q6PKG0|rcsb pdb:4ZC4|rcsb pdb:5C0V|rcsb pdb:5V4R|rcsb pdb:5V7C|rcsb pdb:5V87|rcsb pdb:6PW3 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:+4h5vq/Ef8TvyM0cADeYlak6pd010884 rogid:TjQrZVRN3opAdFIWZtaEopFZf8I9606 intact-crc:3516D68BB0617FFF|rigid:Pj6ENE54LVy8rP3x48dOgKPzHAo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P07939 uniprotkb:Q8IWT3 intact:EBI-6153113 intact:EBI-311123|uniprotkb:O75188|uniprotkb:Q68CP2|uniprotkb:Q68D92|uniprotkb:Q8N3W9|uniprotkb:Q9BU56|intact:EBI-2845754|uniprotkb:Q5TCY3|ensembl:ENSP00000252050 psi-mi:sigm3_reovl(display_long)|uniprotkb:S4(gene name)|psi-mi:S4(display_short) psi-mi:cul9_human(display_long)|uniprotkb:CUL9(gene name)|psi-mi:CUL9(display_short)|uniprotkb:H7AP1(gene name synonym)|uniprotkb:KIAA0708(gene name synonym)|uniprotkb:UbcH7-associated protein 1(gene name synonym)|uniprotkb:PARC(gene name synonym)|uniprotkb:p53-associated parkin-like cytoplasmic protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159787|imex:IM-17331-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000153(Outer capsid sigma 3, reoviral)|interpro:IPR023634|rcsb pdb:1JMU|rcsb pdb:2CSE|rcsb pdb:6XF8|rcsb pdb:6ZTY|rcsb pdb:6ZTZ|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006417"(regulation of translation)|go:"GO:0019058"(viral life cycle)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039624"(viral outer capsid)|go:"GO:0046872"(metal ion binding) refseq:NP_055904.1|ensembl:ENSG00000112659(gene)|ensembl:ENST00000252050(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR017907|interpro:IPR019559|interpro:IPR021097|interpro:IPR031222|interpro:IPR036317|interpro:IPR036388|interpro:IPR044066|mint:Q8IWT3|rcsb pdb:2JUF|reactome:R-HSA-8951664 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:+4h5vq/Ef8TvyM0cADeYlak6pd010884 rogid:l3eOdyfEVm0PkkDykJXN270o1Kc9606 intact-crc:3516D68BB0617FFF|rigid:Pj6ENE54LVy8rP3x48dOgKPzHAo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P07939 uniprotkb:P11940 intact:EBI-6153113 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:sigm3_reovl(display_long)|uniprotkb:S4(gene name)|psi-mi:S4(display_short) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159787|imex:IM-17331-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000153(Outer capsid sigma 3, reoviral)|interpro:IPR023634|rcsb pdb:1JMU|rcsb pdb:2CSE|rcsb pdb:6XF8|rcsb pdb:6ZTY|rcsb pdb:6ZTZ|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006417"(regulation of translation)|go:"GO:0019058"(viral life cycle)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039624"(viral outer capsid)|go:"GO:0046872"(metal ion binding) interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:+4h5vq/Ef8TvyM0cADeYlak6pd010884 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 intact-crc:3516D68BB0617FFF|rigid:Pj6ENE54LVy8rP3x48dOgKPzHAo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P07939 uniprotkb:P16989 intact:EBI-6153113 intact:EBI-358193|uniprotkb:Q14121|uniprotkb:Q969N6|uniprotkb:Q96B76|uniprotkb:B2RBW6|intact:EBI-2560381|ensembl:ENSP00000228251 psi-mi:sigm3_reovl(display_long)|uniprotkb:S4(gene name)|psi-mi:S4(display_short) psi-mi:ybox3_human(display_long)|uniprotkb:YBX3(gene name)|psi-mi:YBX3(display_short)|uniprotkb:CSDA(gene name synonym)|uniprotkb:Cold shock domain-containing protein A(gene name synonym)|uniprotkb:DBPA(gene name synonym)|uniprotkb:DNA-binding protein A(gene name synonym)|uniprotkb:Single-strand DNA-binding protein NF-GMB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159787|imex:IM-17331-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000153(Outer capsid sigma 3, reoviral)|interpro:IPR023634|rcsb pdb:1JMU|rcsb pdb:2CSE|rcsb pdb:6XF8|rcsb pdb:6ZTY|rcsb pdb:6ZTZ|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006417"(regulation of translation)|go:"GO:0019058"(viral life cycle)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039624"(viral outer capsid)|go:"GO:0046872"(metal ion binding) go:"GO:0046622"(positive regulation of organ growth)|refseq:NP_001138898.1|refseq:NP_003642.3|dip:DIP-42489N|ensembl:ENSG00000060138(gene)|ensembl:ENST00000228251(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008584"(male gonad development)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031267"(small GTPase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:1902219"(negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1905538"(polysome binding)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P16989 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:+4h5vq/Ef8TvyM0cADeYlak6pd010884 rogid:cWuhmwOBWe5HdgPG1gyN7KzN4Rs9606 intact-crc:3516D68BB0617FFF|rigid:Pj6ENE54LVy8rP3x48dOgKPzHAo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P07939 uniprotkb:P55084 intact:EBI-6153113 intact:EBI-356635|uniprotkb:Q9T2V8|uniprotkb:O14969|uniprotkb:Q53TA6|uniprotkb:Q96C77|uniprotkb:Q9H3F5|uniprotkb:B2RB16|intact:EBI-2948478|ensembl:ENSP00000325136|intact:EBI-8012123|intact:MINT-8395035|uniprotkb:B4E2W0 psi-mi:sigm3_reovl(display_long)|uniprotkb:S4(gene name)|psi-mi:S4(display_short) psi-mi:echb_human(display_long)|uniprotkb:HADHB(gene name)|psi-mi:HADHB(display_short)|uniprotkb:MSTP029(orf name)|uniprotkb:TP-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159787|imex:IM-17331-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000153(Outer capsid sigma 3, reoviral)|interpro:IPR023634|rcsb pdb:1JMU|rcsb pdb:2CSE|rcsb pdb:6XF8|rcsb pdb:6ZTY|rcsb pdb:6ZTZ|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006417"(regulation of translation)|go:"GO:0019058"(viral life cycle)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039624"(viral outer capsid)|go:"GO:0046872"(metal ion binding) refseq:NP_000174.1|ensembl:ENSG00000138029(gene)|ensembl:ENST00000317799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P55084|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350|refseq:XP_011531105.1|refseq:NP_001268441.1|refseq:NP_001268442.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:+4h5vq/Ef8TvyM0cADeYlak6pd010884 rogid:4w0QYaw1wLyr5NJOKZ9naymK8kg9606 intact-crc:3516D68BB0617FFF|rigid:Pj6ENE54LVy8rP3x48dOgKPzHAo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P07939 uniprotkb:P67809 intact:EBI-6153113 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 psi-mi:sigm3_reovl(display_long)|uniprotkb:S4(gene name)|psi-mi:S4(display_short) psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159787|imex:IM-17331-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000153(Outer capsid sigma 3, reoviral)|interpro:IPR023634|rcsb pdb:1JMU|rcsb pdb:2CSE|rcsb pdb:6XF8|rcsb pdb:6ZTY|rcsb pdb:6ZTZ|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006417"(regulation of translation)|go:"GO:0019058"(viral life cycle)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039624"(viral outer capsid)|go:"GO:0046872"(metal ion binding) refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:+4h5vq/Ef8TvyM0cADeYlak6pd010884 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 intact-crc:3516D68BB0617FFF|rigid:Pj6ENE54LVy8rP3x48dOgKPzHAo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P07939 uniprotkb:Q13310 intact:EBI-6153113 intact:EBI-372844|uniprotkb:Q6P0N3|uniprotkb:B1ANQ8|ensembl:ENSP00000361948|intact:EBI-877641|uniprotkb:Q4VC03 psi-mi:sigm3_reovl(display_long)|uniprotkb:S4(gene name)|psi-mi:S4(display_short) psi-mi:pabp4_human(display_long)|uniprotkb:PABPC4(gene name)|psi-mi:PABPC4(display_short)|uniprotkb:APP1(gene name synonym)|uniprotkb:PABP4(gene name synonym)|uniprotkb:"Inducible poly(A)-binding protein"(gene name synonym)|uniprotkb:Activated-platelet protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159787|imex:IM-17331-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000153(Outer capsid sigma 3, reoviral)|interpro:IPR023634|rcsb pdb:1JMU|rcsb pdb:2CSE|rcsb pdb:6XF8|rcsb pdb:6ZTY|rcsb pdb:6ZTZ|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006417"(regulation of translation)|go:"GO:0019058"(viral life cycle)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039624"(viral outer capsid)|go:"GO:0046872"(metal ion binding) refseq:NP_001129126.1|refseq:NP_003810.1|ensembl:ENSG00000090621(gene)|ensembl:ENST00000372857(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006412"(translation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0061515"(myeloid cell development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:Q13310|refseq:NP_001129125.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:+4h5vq/Ef8TvyM0cADeYlak6pd010884 rogid:u1qCM3o5X7jLIa1vyqFCIH7v01w9606 intact-crc:3516D68BB0617FFF|rigid:Pj6ENE54LVy8rP3x48dOgKPzHAo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P07939 uniprotkb:Q15393 intact:EBI-6153113 intact:EBI-346977|uniprotkb:Q6NTI8|uniprotkb:Q96GC0|uniprotkb:Q9BPY2|uniprotkb:Q9UFX7|uniprotkb:Q9UJ29|ensembl:ENSP00000305790 psi-mi:sigm3_reovl(display_long)|uniprotkb:S4(gene name)|psi-mi:S4(display_short) psi-mi:sf3b3_human(display_long)|uniprotkb:SF3B3(gene name)|psi-mi:SF3B3(display_short)|uniprotkb:KIAA0017(gene name synonym)|uniprotkb:SAP130(gene name synonym)|uniprotkb:Spliceosome-associated protein 130(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 130 kDa subunit(gene name synonym)|uniprotkb:STAF130(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159787|imex:IM-17331-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000153(Outer capsid sigma 3, reoviral)|interpro:IPR023634|rcsb pdb:1JMU|rcsb pdb:2CSE|rcsb pdb:6XF8|rcsb pdb:6ZTY|rcsb pdb:6ZTZ|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006417"(regulation of translation)|go:"GO:0019058"(viral life cycle)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039624"(viral outer capsid)|go:"GO:0046872"(metal ion binding) refseq:NP_036558.3|dip:DIP-28152N|ensembl:ENSG00000189091(gene)|ensembl:ENST00000302516(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|rcsb pdb:5O9Z|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|go:"GO:0005730"(nucleolus)|go:"GO:0008380"(RNA splicing)|rcsb pdb:5ZYA|rcsb pdb:6AH0|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR036322|mint:Q15393|rcsb pdb:5IFE - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:+4h5vq/Ef8TvyM0cADeYlak6pd010884 rogid:gnCSXjZ/bwNXair6kyQUKoKIwbM9606 intact-crc:3516D68BB0617FFF|rigid:Pj6ENE54LVy8rP3x48dOgKPzHAo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P07939 uniprotkb:Q13435 intact:EBI-6153113 intact:EBI-749111|uniprotkb:A8K485|uniprotkb:B4DT19|uniprotkb:Q7Z627|uniprotkb:Q969K1|uniprotkb:Q96CM6|uniprotkb:Q9BWD2|intact:EBI-1052093|intact:EBI-2688256|uniprotkb:Q7L4T5|ensembl:ENSP00000318861 psi-mi:sigm3_reovl(display_long)|uniprotkb:S4(gene name)|psi-mi:S4(display_short) psi-mi:sf3b2_human(display_long)|uniprotkb:SF3B2(gene name)|psi-mi:SF3B2(display_short)|uniprotkb:SAP145(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 145 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 145(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159787|imex:IM-17331-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000153(Outer capsid sigma 3, reoviral)|interpro:IPR023634|rcsb pdb:1JMU|rcsb pdb:2CSE|rcsb pdb:6XF8|rcsb pdb:6ZTY|rcsb pdb:6ZTZ|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006417"(regulation of translation)|go:"GO:0019058"(viral life cycle)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039624"(viral outer capsid)|go:"GO:0046872"(metal ion binding) refseq:NP_006833.2|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006568(PSP, proline-rich)|ensembl:ENSG00000087365(gene)|ensembl:ENST00000322535(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR007180(Protein of unknown function DUF382)|rcsb pdb:2DO5|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y53|mint:Q13435|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:+4h5vq/Ef8TvyM0cADeYlak6pd010884 rogid:Y9uCV2x4J5kqyxeO8iXjojkXocA9606 intact-crc:3516D68BB0617FFF|rigid:Pj6ENE54LVy8rP3x48dOgKPzHAo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P07939 uniprotkb:Q14999 intact:EBI-6153113 intact:EBI-308606|uniprotkb:Q5T654|ensembl:ENSP00000265348|uniprotkb:B4DYZ0|uniprotkb:F5H0L1 psi-mi:sigm3_reovl(display_long)|uniprotkb:S4(gene name)|psi-mi:S4(display_short) psi-mi:cul7_human(display_long)|uniprotkb:CUL7(gene name)|psi-mi:CUL7(display_short)|uniprotkb:KIAA0076(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:10884(reovl)|taxid:10884("Reovirus type 1 (strain Lang) (T1L)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159787|imex:IM-17331-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000153(Outer capsid sigma 3, reoviral)|interpro:IPR023634|rcsb pdb:1JMU|rcsb pdb:2CSE|rcsb pdb:6XF8|rcsb pdb:6ZTY|rcsb pdb:6ZTZ|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006417"(regulation of translation)|go:"GO:0019058"(viral life cycle)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039580"(suppression by virus of host PKR signaling)|go:"GO:0039624"(viral outer capsid)|go:"GO:0046872"(metal ion binding) ensembl:ENSG00000044090(gene)|ensembl:ENST00000265348(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001890"(placenta development)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:1990393"(3M complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR021097|interpro:IPR031223|interpro:IPR036317|interpro:IPR036388|mint:Q14999|rcsb pdb:2JNG|reactome:R-HSA-381038|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_001161842.1|refseq:NP_055595.2|dip:DIP-31618N|dip:DIP-60187N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2014/10/16 rogid:+4h5vq/Ef8TvyM0cADeYlak6pd010884 rogid:8sODZSppCsuEgRmhSHp3UjwOf2M9606 intact-crc:3516D68BB0617FFF|rigid:Pj6ENE54LVy8rP3x48dOgKPzHAo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:Q6NXT2 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-2868501|uniprotkb:E9P281|ensembl:ENSP00000339835 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:h3c_human(display_long)|uniprotkb:H3-5(gene name)|psi-mi:H3-5(display_short)|uniprotkb:H3F3C(gene name synonym)|uniprotkb:Histone H3.5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) refseq:NP_001013721.2|go:"GO:0006997"(nucleus organization)|go:"GO:0007286"(spermatid development)|go:"GO:0007338"(single fertilization)|go:"GO:0007566"(embryo implantation)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0090230"(regulation of centromere complex assembly)|go:"GO:1902340"(negative regulation of chromosome condensation)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q6NXT2|rcsb pdb:2PUY|rcsb pdb:3KV4|rcsb pdb:4Z5T|rcsb pdb:5BWN|rcsb pdb:5BWO|rcsb pdb:5F6K|rcsb pdb:5I3L|rcsb pdb:6OI3|ensembl:ENSG00000188375(gene)|ensembl:ENST00000340398(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001740"(Barr body)|go:"GO:0005634"(nucleus) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:d8jgPwPl7fXRRpWh+ON9tiyrgnY9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:P84243 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-120658|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q5VV55|uniprotkb:Q5VV56|uniprotkb:Q66I33|uniprotkb:Q9V3W4|ensembl:ENSP00000254810|ensembl:ENSP00000355778|ensembl:ENSP00000355780|ensembl:ENSP00000355781|ensembl:ENSP00000465813|ensembl:ENSP00000466020|ensembl:ENSP00000468714|ensembl:ENSP00000499275|ensembl:ENSP00000499385|ensembl:ENSP00000499800 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:h33_human(display_long)|uniprotkb:H3-3A(gene name)|psi-mi:H3-3A(display_short)|uniprotkb:H3-3B(gene name)|psi-mi:H3-3B(display_short)|uniprotkb:H3.3A(gene name synonym)|uniprotkb:H3.3B(gene name synonym)|uniprotkb:H3F3(gene name synonym)|uniprotkb:H3F3A(gene name synonym)|uniprotkb:H3F3B(gene name synonym)|uniprotkb:PP781(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) refseq:NP_002098.1|refseq:NP_005315.1|rcsb pdb:4H9N|rcsb pdb:3QL9|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:3QLA|rcsb pdb:3QLC|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4L58|rcsb pdb:4N4I|rcsb pdb:3WTP|rcsb pdb:4O62|rcsb pdb:4QQ4|rcsb pdb:4TMP|rcsb pdb:4GNE|rcsb pdb:4GNF|rcsb pdb:4U7T|rcsb pdb:4GNG|rcsb pdb:4W5A|rcsb pdb:4GU0|rcsb pdb:4GUR|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:4GUS|rcsb pdb:4GY5|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5JA4|rcsb pdb:5JJY|ensembl:ENSG00000132475(gene)|ensembl:ENSG00000163041(gene)|rcsb pdb:5JLB|rcsb pdb:5KDM|rcsb pdb:5X7X|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6HGT|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6J9J|rcsb pdb:6PZV|rcsb pdb:6QXZ|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6U04|rcsb pdb:7A08|reactome:R-HSA-427413|rcsb pdb:7CIZ|reactome:R-HSA-5250924|reactome:R-HSA-5334118|rcsb pdb:7CJ0|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-983231|rcsb pdb:7CWH|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-427359|reactome:R-HSA-427389|ensembl:ENST00000254810(transcript)|ensembl:ENST00000366813(transcript)|ensembl:ENST00000366815(transcript)|ensembl:ENST00000366816(transcript)|ensembl:ENST00000586607(transcript)|ensembl:ENST00000587560(transcript)|ensembl:ENST00000589599(transcript)|ensembl:ENST00000655399(transcript)|ensembl:ENST00000661429(transcript)|ensembl:ENST00000666609(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P84243|rcsb pdb:2L43|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3AV2|rcsb pdb:3JVK|rcsb pdb:3MUK|rcsb pdb:3MUL|dip:DIP-40046N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:cRqA5/IBNfIbbxAnbwLqzXip20I9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:O43791 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-743549|uniprotkb:Q53HJ1|uniprotkb:B2R6S3|uniprotkb:D3DTW7|ensembl:ENSP00000240327|ensembl:ENSP00000377001|ensembl:ENSP00000420908|ensembl:ENSP00000424119|ensembl:ENSP00000425905|ensembl:ENSP00000426986|ensembl:ENSP00000499562 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:spop_human(display_long)|uniprotkb:HIB homolog 1(gene name synonym)|uniprotkb:Roadkill homolog 1(gene name synonym)|uniprotkb:SPOP(gene name)|psi-mi:SPOP(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) refseq:NP_001007227.1|refseq:NP_001007228.1|refseq:NP_001007229.1|refseq:NP_001007230.1|refseq:NP_001007231.1|refseq:NP_003554.1|refseq:XP_005257780.1|refseq:XP_005257781.1|ensembl:ENSG00000121067(gene)|ensembl:ENST00000347630(transcript)|ensembl:ENST00000393328(transcript)|ensembl:ENST00000503676(transcript)|ensembl:ENST00000504102(transcript)|ensembl:ENST00000509079(transcript)|ensembl:ENST00000514121(transcript)|ensembl:ENST00000665825(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR034089|mint:O43791|rcsb pdb:2CR2|rcsb pdb:3HQH|rcsb pdb:3HQI|rcsb pdb:3HQL|rcsb pdb:3HQM|rcsb pdb:3HSV|rcsb pdb:3HTM|rcsb pdb:3HU6|rcsb pdb:3IVB|rcsb pdb:3IVQ|rcsb pdb:3IVV|rcsb pdb:4EOZ|rcsb pdb:4HS2|rcsb pdb:4J8Z|rcsb pdb:4O1V|rcsb pdb:6F8F|rcsb pdb:6F8G|rcsb pdb:6I41|rcsb pdb:6I5P|rcsb pdb:6I68|rcsb pdb:6I7A|rcsb pdb:7D3D|rcsb pdb:7LIN|rcsb pdb:7LIO|rcsb pdb:7LIP|rcsb pdb:7LIQ|reactome:R-HSA-5632684|go:"GO:0005634"(nucleus)|refseq:XP_016880693.1|dip:DIP-50517N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:PC9ofpvk14xwTnnqT590/YRnx/49606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:Q14974 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:A8CG34 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-2880179|ensembl:ENSP00000476236|uniprotkb:O75115|uniprotkb:Q9Y4S7|uniprotkb:Q9Y2N3|uniprotkb:A0A075B7F8|uniprotkb:A0A087WY75 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:p121c_human(display_long)|uniprotkb:POM121C(gene name)|psi-mi:POM121C(display_short)|uniprotkb:Nuclear pore membrane protein 121-2(gene name synonym)|uniprotkb:Pore membrane protein of 121 kDa C(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-5619107|ensembl:ENST00000607367(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|interpro:IPR026054|interpro:IPR026090|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|ensembl:ENSG00000272391(gene)|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-165054|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|ensembl:ENSP00000476236|ensembl:ENST00000615331|ensembl:ENSP00000481575 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:eUcsTyNISsNFsSxbHCO5VuhzB4E9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:Q71UM5 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-355126|uniprotkb:Q9BTJ1|ensembl:ENSP00000331019 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:rs27l_human(display_long)|uniprotkb:RPS27L(gene name)|psi-mi:RPS27L(display_short)|uniprotkb:Small ribosomal subunit protein eS27-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) refseq:NP_057004.1|ensembl:ENSG00000185088(gene)|ensembl:ENST00000330964(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0006412"(translation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008494"(translation activator activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:Q71UM5|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:OVIAlDF6dN3DxLZgQFrFl8r0Z0I9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:P49790 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-286779|uniprotkb:Q5T9I7|intact:EBI-1237421|uniprotkb:E7EPX5|uniprotkb:Q4LE47|uniprotkb:Q7Z743|uniprotkb:B4DIK2|uniprotkb:F6QR24|ensembl:ENSP00000262077 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:nu153_human(display_long)|uniprotkb:Nucleoporin Nup153(gene name synonym)|uniprotkb:153 kDa nucleoporin(gene name synonym)|uniprotkb:NUP153(gene name)|psi-mi:NUP153(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) ensembl:ENSP00000262077|ensembl:ENST00000537253|ensembl:ENSP00000444029|ensembl:ENST00000613258|ensembl:ENSP00000478627|refseq:NP_005115.2|refseq:NP_001265138.1|refseq:NP_001265139.1|dip:DIP-38185N|ensembl:ENSG00000124789(gene)|ensembl:ENST00000262077(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043657"(host cell)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046832"(negative regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR013913(Nucleoporin, Nup153-like)|interpro:IPR018892|interpro:IPR026054|interpro:IPR036443|mint:P49790|rcsb pdb:2EBQ|rcsb pdb:2EBR|rcsb pdb:2EBV|rcsb pdb:2GQE|rcsb pdb:4U0C|rcsb pdb:4U0D|rcsb pdb:5TSV|rcsb pdb:5TSX|rcsb pdb:6AYA|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:rOax/ikcAu5fmDiCOauVr7Y/fzY9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:Q8IXQ5 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-6153160|uniprotkb:Q9BQF8|uniprotkb:Q9UDQ9|uniprotkb:Q96MV2|uniprotkb:Q7Z765|uniprotkb:A4D144|uniprotkb:B7Z5I9|uniprotkb:G5E9G3|ensembl:ENSP00000343273 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:klhl7_human(display_long)|uniprotkb:KLHL7(gene name)|psi-mi:KLHL7(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) refseq:XP_016867928.1|refseq:NP_001026880.2|refseq:NP_001165899.1|refseq:NP_061334.4|ensembl:ENSG00000122550(gene)|ensembl:ENST00000339077(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030599|rcsb pdb:3II7 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:5TeaKGt0l8SIlxyrzn0t+8WRc6k9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:Q00325 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325 - - crc64:78714C85931B22D5 figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:Q16695 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-358900|uniprotkb:Q6FGU4|uniprotkb:B2R5K3|ensembl:ENSP00000355657|ensembl:ENSP00000494070 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:h31t_human(display_long)|uniprotkb:H3-4(gene name)|psi-mi:H3-4(display_short)|uniprotkb:H3/g(gene name synonym)|uniprotkb:H3FT(gene name synonym)|uniprotkb:HIST3H3(gene name synonym)|uniprotkb:Histone H3.4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) refseq:NP_003484.1|ensembl:ENSG00000168148(gene)|ensembl:ENSG00000285435(gene)|ensembl:ENST00000366696(transcript)|ensembl:ENST00000644869(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q16695|rcsb pdb:2V1D|rcsb pdb:2YBP|rcsb pdb:2YBS|rcsb pdb:3A6N|rcsb pdb:3T6R|rcsb pdb:4V2V|rcsb pdb:4V2W|rcsb pdb:6OIE|rcsb pdb:6WAT|rcsb pdb:6WAU|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-201722|reactome:R-HSA-2299718|reactome:R-HSA-2559586|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-9670095|dip:DIP-922N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:izXHIcNCPCDQ7yevMtqWxTRt1bA9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:P68104 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-352162|uniprotkb:P04719|uniprotkb:P04720|intact:EBI-2834776|intact:EBI-8011754|intact:MINT-4903558|uniprotkb:Q6IQ15|ensembl:ENSP00000330054|ensembl:ENSP00000339053|ensembl:ENSP00000339063|ensembl:ENSP00000348651|ensembl:ENSP00000392366|ensembl:ENSP00000479055|ensembl:ENSP00000503192|ensembl:ENSP00000503249|ensembl:ENSP00000503823|ensembl:ENSP00000504335|intact:EBI-16423274 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:ef1a1_human(display_long)|uniprotkb:EEF1A1(gene name)|psi-mi:EEF1A1(display_short)|uniprotkb:EEF1A(gene name synonym)|uniprotkb:EF1A(gene name synonym)|uniprotkb:LENG7(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) refseq:XP_011533816.1|ensembl:ENSG00000156508(gene)|ensembl:ENST00000309268(transcript)|ensembl:ENST00000316292(transcript)|ensembl:ENST00000331523(transcript)|ensembl:ENST00000356303(transcript)|ensembl:ENST00000455918(transcript)|ensembl:ENST00000615060(transcript)|ensembl:ENST00000676710(transcript)|ensembl:ENST00000677236(transcript)|ensembl:ENST00000678508(transcript)|ensembl:ENST00000678702(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P68104|rcsb pdb:1SYW|rcsb pdb:3C5J|rcsb pdb:6ZMO|reactome:R-HSA-156842|reactome:R-HSA-156902|reactome:R-HSA-3371511|reactome:R-HSA-6798695|reactome:R-HSA-8876725|reactome:R-HSA-9613829|dip:DIP-31277N|refseq:NP_001393.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:d3REF87FDKboAjyvlJJEXtqhrcw9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:Q00839 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-351126|uniprotkb:O75507|uniprotkb:Q8N174|uniprotkb:Q96HY9|uniprotkb:Q9BQ09|ensembl:ENSP00000491215 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:hnrpu_human(display_long)|uniprotkb:HNRNPU(gene name)|psi-mi:HNRNPU(display_short)|uniprotkb:SAFA(gene name synonym)|uniprotkb:U21.1(gene name synonym)|uniprotkb:HNRPU(gene name synonym)|uniprotkb:p120(gene name synonym)|uniprotkb:pp120(gene name synonym)|uniprotkb:C1orf199(gene name synonym)|uniprotkb:GRIP120(gene name synonym)|uniprotkb:Nuclear p120 ribonucleoprotein(gene name synonym)|uniprotkb:Scaffold-attachment factor A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) refseq:NP_004492.2|refseq:NP_114032.2|ensembl:ENSG00000153187(gene)|ensembl:ENST00000640218(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:1990498"(mitotic spindle microtubule)|go:"GO:0098577"(inactive sex chromosome)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR026745|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q00839|rcsb pdb:1ZRJ|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1902425"(positive regulation of attachment of mitotic spindle microtubules to kinetochore)|go:"GO:1902889"(protein localization to spindle microtubule)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:1990280"(RNA localization to chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005813"(centrosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006396"(RNA processing)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008143"("poly(A) binding")|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0017130"("poly(C) RNA binding")|go:"GO:0030496"(midbody)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051301"(cell division)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|refseq:XP_016856604.1|refseq:XP_016856605.1|refseq:XP_016856606.1|dip:DIP-684N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:n73PY0Vis+D5Iq0q77h5Ck2V4789606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:P07437 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:Q8N163 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|ensembl:ENSP00000310670|ensembl:ENSP00000373930|uniprotkb:B2RB79|uniprotkb:D3DSR6 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) refseq:NP_066997.3|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|interpro:IPR028811|mint:Q8N163|reactome:R-HSA-3371453|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|dip:DIP-38122N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:Q93008 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-302524|intact:EBI-1058656|intact:EBI-28978998|ensembl:ENSP00000367558|uniprotkb:O75550|uniprotkb:Q8WWT3|uniprotkb:Q8WX12 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:usp9x_human(display_long)|uniprotkb:USP9X(gene name)|psi-mi:USP9X(display_short)|uniprotkb:DFFRX(gene name synonym)|uniprotkb:USP9(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease FAF-X(gene name synonym)|uniprotkb:Deubiquitinating enzyme FAF-X(gene name synonym)|uniprotkb:Fat facets protein-related, X-linked(gene name synonym)|uniprotkb:Ubiquitin-specific protease 9, X chromosome(gene name synonym)|uniprotkb:FAM(gene name synonym)|uniprotkb:Fat facets in mammals(gene name synonym)|uniprotkb:Ubiquitin thioesterase FAF-X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) ensembl:ENSG00000124486(gene)|ensembl:ENST00000378308(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007292"(female gamete generation)|go:"GO:0008104"(protein localization)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030426"(growth cone)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|reactome:R-HSA-2173795|reactome:R-HSA-5689880|reactome:R-HSA-8866652|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9033241|reactome:R-HSA-977225|go:"GO:0048675"(axon extension)|refseq:NP_001034679.2|refseq:NP_001034680.2|go:"GO:0050821"(protein stabilization)|go:"GO:0051301"(cell division)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0071947"(protein deubiquitination involved in ubiquitin-dependent protein catabolic process)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018200|interpro:IPR021905|interpro:IPR028889|interpro:IPR031226|interpro:IPR038765|mint:Q93008|rcsb pdb:5VBD|rcsb pdb:5WCH|ensembl:ENST00000324545|ensembl:ENSP00000316357|ensembl:ENSP00000367558|dip:DIP-27562N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:f9AWz8rAV8rMTqcQ46VrYYLTHq89606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:Q969G3 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-455078|uniprotkb:O43539|uniprotkb:C0IMW4|uniprotkb:B3KMC1|uniprotkb:B4DFR4|uniprotkb:C0IMW5|uniprotkb:C0IMW7|uniprotkb:H7C3F6|ensembl:ENSP00000323967|ensembl:ENSP00000496094 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:smce1_human(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:SMARCE1(gene name)|psi-mi:SMARCE1(display_short)|uniprotkb:BAF57(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) refseq:NP_003070.3|dip:DIP-27614N|dip:DIP-33041N|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:Q969G3|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:7CYU|reactome:R-HSA-3214858|reactome:R-HSA-8939243|ensembl:ENSG00000073584(gene)|ensembl:ENST00000348513(transcript)|ensembl:ENST00000643683(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:wf7PrAelShE+8xAwb/UdWKWDkyE9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:Q9Y4I1 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-1054086|uniprotkb:O60653|uniprotkb:Q07902|uniprotkb:Q16249|uniprotkb:Q9UE30|uniprotkb:Q9UE31|uniprotkb:A8MZC5|ensembl:ENSP00000382177 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:myo5a_human(display_long)|uniprotkb:Dilute myosin heavy chain, non-muscle(gene name synonym)|uniprotkb:Myosin heavy chain 12(gene name synonym)|uniprotkb:Myoxin(gene name synonym)|uniprotkb:MYO5A(gene name)|psi-mi:MYO5A(display_short)|uniprotkb:MYH12(gene name synonym)|uniprotkb:Myosin-12(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) refseq:NP_000250.3|refseq:XP_005254454.1|ensembl:ENSG00000197535(gene)|ensembl:ENST00000399231(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016459"(myosin complex)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030426"(growth cone)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0032433"(filopodium tip)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002710(Dilute)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR036103|interpro:IPR036961|interpro:IPR037988|mint:Q9Y4I1|rcsb pdb:4D07|rcsb pdb:4J5L|rcsb pdb:4LLI|rcsb pdb:4LX1|rcsb pdb:4LX2|rcsb pdb:5JCY|rcsb pdb:5JCZ|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-264876|reactome:R-HSA-9664422 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:z4bbPG/RrXSmBWT6I0nbIztGp809606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:O60684 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-359923|uniprotkb:Q5VVU3|uniprotkb:B2RDC7|ensembl:ENSP00000362728|uniprotkb:D3DPP5 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:ima7_human(display_long)|uniprotkb:KPNA6(gene name)|psi-mi:KPNA6(display_short)|uniprotkb:IPOA7(gene name synonym)|uniprotkb:Karyopherin subunit alpha-6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) refseq:NP_036448.1|ensembl:ENSG00000025800(gene)|ensembl:ENST00000373625(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0019079"(viral genome replication)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0043657"(host cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O60684|rcsb pdb:4UAD|dip:DIP-27609N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:3NsSIcE6BHIqYlvfGRolUKD/5uc9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:Q92688 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-762428|uniprotkb:O00655|uniprotkb:P78458|uniprotkb:P78459|uniprotkb:B2R9C7|ensembl:ENSP00000345848 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:an32b_human(display_long)|uniprotkb:Acidic protein rich in leucines(gene name synonym)|uniprotkb:Silver-stainable protein SSP29(gene name synonym)|uniprotkb:ANP32B(gene name)|psi-mi:ANP32B(display_short)|uniprotkb:APRIL(gene name synonym)|uniprotkb:PHAPI2(gene name synonym)|uniprotkb:Putative HLA-DR-associated protein I-2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) refseq:NP_006392.1|ensembl:ENSG00000136938(gene)|ensembl:ENST00000339399(transcript)|go:"GO:0001944"(vasculature development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0021591"(ventricular system development)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048839"(inner ear development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:Q92688|rcsb pdb:2ELL|rcsb pdb:2RR6|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:8eu0C8oHWUrZ28F2fIup9o5MDYk9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:Q05639 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-354943|ensembl:ENSP00000217182|uniprotkb:P54266|uniprotkb:Q0VGC7|uniprotkb:B5BUF3|uniprotkb:E1P5J1 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:ef1a2_human(display_long)|uniprotkb:EEF1A2(gene name)|psi-mi:EEF1A2(display_short)|uniprotkb:EEF1AL(gene name synonym)|uniprotkb:STN(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-2(gene name synonym)|uniprotkb:Statin-S1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) ensembl:ENSG00000101210(gene)|ensembl:ENST00000217182(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0090218"(positive regulation of lipid kinase activity)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:Q05639|rcsb pdb:3C5J|reactome:R-HSA-156842|refseq:NP_001949.1|dip:DIP-40060N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:vFXfcSRokxKo5RW0tRE1qEK0NKw9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:Q5VTE0 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-877809 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:ef1a3_human(display_long)|uniprotkb:EEF1A1P5(gene name)|psi-mi:EEF1A1P5(display_short)|uniprotkb:Eukaryotic elongation factor 1 A-like 3(gene name synonym)|uniprotkb:EEF1AL3(gene name synonym)|uniprotkb:Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR031157|reactome:R-HSA-156842|interpro:IPR027417 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:3t6tj3i+3CKTC1NsrHyBkeoRK789606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:P62805 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:Q9BQE3 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:P39687 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-359234|uniprotkb:Q53FK4|uniprotkb:Q5J8L8|uniprotkb:Q7M4N6|uniprotkb:B2R6T4|ensembl:ENSP00000417864 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:an32a_human(display_long)|uniprotkb:ANP32A(gene name)|psi-mi:ANP32A(display_short)|uniprotkb:LANP(gene name synonym)|uniprotkb:PHAP1(gene name synonym)|uniprotkb:C15orf1(gene name synonym)|uniprotkb:MAPM(gene name synonym)|uniprotkb:Potent heat-stable protein phosphatase 2A inhibitor I1PP2A(gene name synonym)|uniprotkb:Acidic nuclear phosphoprotein pp32(gene name synonym)|uniprotkb:Leucine-rich acidic nuclear protein(gene name synonym)|uniprotkb:Putative HLA-DR-associated protein I(gene name synonym)|uniprotkb:Mapmodulin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) refseq:NP_006296.1|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|mint:P39687|rcsb pdb:2JE0|rcsb pdb:2JE1|rcsb pdb:4XOS|rcsb pdb:6XZQ|reactome:R-HSA-450520|ensembl:ENSG00000140350(gene)|ensembl:ENST00000465139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:uyR/0ZiQuJsE2V1LbRJQiLs+IH49606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:P14866 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-719024|uniprotkb:Q9H3P3|uniprotkb:A6ND69|uniprotkb:A6NIT8|ensembl:ENSP00000221419|ensembl:ENSP00000489021 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:hnrpl_human(display_long)|uniprotkb:HNRPL(gene name synonym)|uniprotkb:HNRNPL(gene name)|psi-mi:HNRNPL(display_short)|uniprotkb:P/OKcl.14(orf name) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) refseq:NP_001005335.1|refseq:NP_001524.2|refseq:XP_011525191.1|ensembl:ENSG00000282947(gene)|ensembl:ENST00000221419(transcript)|ensembl:ENST00000634753(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097157"(pre-mRNA intronic binding)|ensembl:ENSG00000104824(gene)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034816|interpro:IPR034817|interpro:IPR035005|interpro:IPR035008|interpro:IPR035979|mint:P14866|rcsb pdb:3R27|rcsb pdb:3TO8|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:1990904"(ribonucleoprotein complex)|dip:DIP-36355N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:vOfznm03e6Ottg6BptYHmR9qJEc9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:Q9NQ55 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-1048540|uniprotkb:Q9BW97|uniprotkb:Q9H170|uniprotkb:C9J3F9|ensembl:ENSP00000253107 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:ssf1_human(display_long)|uniprotkb:Peter Pan homolog(gene name synonym)|uniprotkb:PPAN(gene name)|psi-mi:PPAN(display_short)|uniprotkb:SSF1(gene name synonym)|uniprotkb:BXDC3(gene name synonym)|uniprotkb:Brix domain-containing protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) refseq:NP_001035754.1|refseq:NP_064615.3|ensembl:ENSG00000130810(gene)|ensembl:ENST00000253107(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR007109(Brix)|mint:Q9NQ55 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:wIgMQj/xJrj5eExsyZD6BeamQOQ9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:P42677 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-356336|ensembl:ENSP00000499044|uniprotkb:Q5T4L6 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:rs27_human(display_long)|uniprotkb:RPS27(gene name)|psi-mi:RPS27(display_short)|uniprotkb:MPS1(gene name synonym)|uniprotkb:Metallopan-stimulin 1(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS27(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) refseq:NP_001021.1|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|ensembl:ENSG00000177954(gene)|ensembl:ENST00000651669(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:P42677|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-141444|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-2500257|rcsb pdb:6OM7|reactome:R-HSA-5663220|reactome:R-HSA-6791226|reactome:R-HSA-68877|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-9648025|reactome:R-HSA-975956|reactome:R-HSA-975957|dip:DIP-44182N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:OA5IWAJDBpY5FFdVnun7Sq/jI7g9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:Q8TAQ2 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-357418|ensembl:ENSP00000267064|uniprotkb:Q92923|uniprotkb:Q96E12|uniprotkb:Q96GY4|intact:EBI-1759986|intact:EBI-1965079|uniprotkb:F8VTJ5|uniprotkb:Q59GV3 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:smrc2_human(display_long)|uniprotkb:SMARCC2(gene name)|psi-mi:SMARCC2(display_short)|uniprotkb:BAF170(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2(gene name synonym)|uniprotkb:SWI/SNF complex 170 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 170(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) ensembl:ENSG00000139613(gene)|ensembl:ENST00000267064(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|interpro:IPR038044|mint:Q8TAQ2|rcsb pdb:6KAG|rcsb pdb:6LTH|rcsb pdb:6LTJ|reactome:R-HSA-3214858|reactome:R-HSA-8939243|refseq:NP_003066.2|refseq:NP_001123892.1|refseq:NP_620706.1|refseq:NP_001317217.1|dip:DIP-27611N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:60gIB3J1YI/FzqVCzdoSg1Oj3ME9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:Q9UFW8 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-723153|uniprotkb:O15183|ensembl:ENSP00000381428|ensembl:ENSP00000381429|ensembl:ENSP00000418769|ensembl:ENSP00000420374|ensembl:ENSP00000502581|uniprotkb:D3DU38 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:cgbp1_human(display_long)|uniprotkb:p20-CGGBP DNA-binding protein(gene name synonym)|uniprotkb:20 kDa CGG-binding protein(gene name synonym)|uniprotkb:CGGBP1(gene name)|psi-mi:CGGBP1(display_short)|uniprotkb:CGGBP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) refseq:NP_001008391.1|refseq:NP_001182237.1|refseq:NP_003654.3|ensembl:ENSG00000163320(gene)|ensembl:ENST00000309534(transcript)|ensembl:ENST00000398392(transcript)|ensembl:ENST00000462901(transcript)|ensembl:ENST00000482016(transcript)|ensembl:ENST00000675130(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042802"(identical protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR033375|mint:Q9UFW8|refseq:XP_016862844.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:1sg3JQWhmEQX9snN5SG1OjdRP1A9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:Q9NQX4 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-1237297|uniprotkb:Q6P1W8|ensembl:ENSP00000261839 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:myo5c_human(display_long)|uniprotkb:MYO5C(gene name)|psi-mi:MYO5C(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) refseq:NP_061198.2|ensembl:ENST00000261839(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|ensembl:ENSG00000128833(gene)|go:"GO:0031982"(vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002710(Dilute)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR036103|interpro:IPR036961|interpro:IPR037991|rcsb pdb:4L8T|rcsb pdb:4ZG4|rcsb pdb:5HMP|go:"GO:0030050"(vesicle transport along actin filament) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:p3wlaboghTdnrQ1yGUpURcRHf/A9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:P52294 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-358383|uniprotkb:Q9BQ56|uniprotkb:Q6IBQ9|intact:EBI-1058734|ensembl:ENSP00000343701|uniprotkb:D3DN93 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:ima5_human(display_long)|uniprotkb:KPNA1(gene name)|psi-mi:KPNA1(display_short)|uniprotkb:RCH2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-1(gene name synonym)|uniprotkb:SRP1-beta(gene name synonym)|uniprotkb:RAG cohort protein 2(gene name synonym)|uniprotkb:Nucleoprotein interactor 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) refseq:NP_002255.3|ensembl:ENSG00000114030(gene)|ensembl:ENST00000344337(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014841"(skeletal muscle satellite cell proliferation)|go:"GO:0014901"(satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0030425"(dendrite)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52294|rcsb pdb:2JDQ|rcsb pdb:3TJ3|rcsb pdb:4B18|rcsb pdb:6WX9|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-162592|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180910|reactome:R-HSA-909733|reactome:R-HSA-9636249|dip:DIP-29296N|refseq:XP_005247494.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:eha8sOMYqe0OC6eXBA4eJLLsKFs9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:P51532 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-302489|uniprotkb:O95052|uniprotkb:Q9HBD3|uniprotkb:B1A8Z4|uniprotkb:B1A8Z5|uniprotkb:B1A8Z6|uniprotkb:B1A8Z7|uniprotkb:E9PBR8|ensembl:ENSP00000343896|ensembl:ENSP00000395654 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:smca4_human(display_long)|uniprotkb:SMARCA4(gene name)|psi-mi:SMARCA4(display_short)|uniprotkb:BRG1(gene name synonym)|uniprotkb:SNF2B(gene name synonym)|uniprotkb:SNF2L4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:BAF190A(gene name synonym)|uniprotkb:Mitotic growth and transcription activator(gene name synonym)|uniprotkb:Protein BRG-1(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) refseq:NP_001122316.1|refseq:NP_003063.2|refseq:NP_001122317.1|refseq:NP_001122318.1|refseq:NP_001122319.1|refseq:NP_001122320.1|dip:DIP-24249N|refseq:XP_016882654.1|refseq:XP_016882655.1|refseq:XP_016882656.1|refseq:XP_016882657.1|ensembl:ENSG00000127616(gene)|ensembl:ENST00000344626(transcript)|ensembl:ENST00000429416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0002039"(p53 binding)|go:"GO:0003407"(neural retina development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|mint:P51532|rcsb pdb:2GRC|rcsb pdb:2H60|rcsb pdb:3UVD|rcsb pdb:5DKD|rcsb pdb:5EA1|rcsb pdb:6BGH|rcsb pdb:6HR2|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6SY2|rcsb pdb:6ZS2|reactome:R-HSA-1266695|reactome:R-HSA-201722|reactome:R-HSA-3214858|reactome:R-HSA-3247509|reactome:R-HSA-8939243|reactome:R-HSA-9619665 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:Ztr+2IXfAxueSUaNYG2A47HoMes9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:Q71DI3 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-750650|uniprotkb:A2BDF6|uniprotkb:A6NFS4|uniprotkb:Q6B053|ensembl:ENSP00000333277|ensembl:ENSP00000358154|ensembl:ENSP00000385479 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:h32_human(display_long)|uniprotkb:H3C13(gene name)|psi-mi:H3C13(display_short)|uniprotkb:H3C14(gene name)|psi-mi:H3C14(display_short)|uniprotkb:H3C15(gene name)|psi-mi:H3C15(display_short)|uniprotkb:H3-clustered histone 13(gene name synonym)|uniprotkb:H3-clustered histone 14(gene name synonym)|uniprotkb:H3-clustered histone 15(gene name synonym)|uniprotkb:H3F2(gene name synonym)|uniprotkb:H3FM(gene name synonym)|uniprotkb:HIST2H3A(gene name synonym)|uniprotkb:HIST2H3C(gene name synonym)|uniprotkb:HIST2H3D(gene name synonym)|uniprotkb:Histone H3/m(gene name synonym)|uniprotkb:Histone H3/o(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) refseq:NP_001005464.1|refseq:NP_001116847.1|refseq:NP_066403.2|dip:DIP-48606N|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|rcsb pdb:7BU9|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214858|reactome:R-HSA-3247509|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-983231|rcsb pdb:7JZV|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|ensembl:ENSG00000183598(gene)|ensembl:ENSG00000203811(gene)|ensembl:ENSG00000203852(gene)|ensembl:ENST00000331491(transcript)|ensembl:ENST00000369158(transcript)|ensembl:ENST00000403683(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q71DI3|rcsb pdb:2IIJ|rcsb pdb:2X4W|rcsb pdb:2X4X|rcsb pdb:2X4Y|rcsb pdb:3AV1|rcsb pdb:3DB3|rcsb pdb:3MO8|rcsb pdb:3QO2|rcsb pdb:3R93|rcsb pdb:4MZF|rcsb pdb:4MZG|rcsb pdb:4MZH|rcsb pdb:4OUC|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B40|rcsb pdb:5BO0|rcsb pdb:5CIU|rcsb pdb:5VAC|rcsb pdb:6ACE|rcsb pdb:6FML|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6Y5E|rcsb pdb:7BQZ - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:O15131 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-540602|uniprotkb:Q86X23|uniprotkb:B2RAI5|ensembl:ENSP00000348704|ensembl:ENSP00000357552 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:ima6_human(display_long)|uniprotkb:Karyopherin subunit alpha-5(gene name synonym)|uniprotkb:KPNA5(gene name)|psi-mi:KPNA5(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) refseq:NP_002260.2|reactome:R-HSA-1169408|reactome:R-HSA-168276|rcsb pdb:4U2X|ensembl:ENSG00000196911(gene)|ensembl:ENST00000356348(transcript)|ensembl:ENST00000368564(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O15131|refseq:XP_016866328.1|refseq:XP_016866329.1|dip:DIP-33405N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:ixGSmHZKndxkY0NFF1Adu+7SmEA9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:Q96HA1 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-739990|ensembl:ENSP00000405562|uniprotkb:A8MXF9|uniprotkb:O75115|uniprotkb:Q9Y4S7|intact:EBI-948778|uniprotkb:A6NFS9|uniprotkb:A8CDT4|uniprotkb:A8K933|uniprotkb:Q96DI0|uniprotkb:Q9H9X1|uniprotkb:Q9Y2N3 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:p121a_human(display_long)|uniprotkb:POM121(gene name)|psi-mi:POM121(display_short)|uniprotkb:KIAA0618(gene name synonym)|uniprotkb:NUP121(gene name synonym)|uniprotkb:POM121A(gene name synonym)|uniprotkb:Pore membrane protein of 121 kDa(gene name synonym)|uniprotkb:Nuclear envelope pore membrane protein POM 121A(gene name synonym)|uniprotkb:Nucleoporin Nup121(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) ensembl:ENSG00000196313(gene)|ensembl:ENST00000434423(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|interpro:IPR026054|interpro:IPR026090|rcsb pdb:5T6W|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|refseq:NP_001244119.1|ensembl:ENST00000358357|ensembl:ENSP00000351124|ensembl:ENST00000395270|ensembl:ENSP00000378687|ensembl:ENSP00000405562|ensembl:ENST00000446813|ensembl:ENSP00000393020|ensembl:ENST00000627934|ensembl:ENSP00000486504|reactome:R-HSA-165054|refseq:NP_742017.1|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|refseq:XP_005250783.1|refseq:XP_006716259.1|refseq:XP_016868342.1|refseq:XP_016868343.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:lQ9VaBl42KMRJaM4UdF4ng9ZX549606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05322 uniprotkb:P68431 intact:EBI-6153153|uniprotkb:Q8JS60|uniprotkb:Q9DQD2|uniprotkb:Q773N1 intact:EBI-79722|ensembl:ENSP00000352252|ensembl:ENSP00000358160|ensembl:ENSP00000366999|ensembl:ENSP00000480826|ensembl:ENSP00000482271|ensembl:ENSP00000483283|ensembl:ENSP00000484095|ensembl:ENSP00000484638|ensembl:ENSP00000484658|ensembl:ENSP00000484841|ensembl:ENSP00000489282|intact:EBI-1560041|uniprotkb:A0PJT7|uniprotkb:P02295|uniprotkb:P02296|uniprotkb:P16106|uniprotkb:Q6ISV8|uniprotkb:Q6NWP8|uniprotkb:Q6NWP9|uniprotkb:Q6NXU4|uniprotkb:Q71DJ3|uniprotkb:Q93081|uniprotkb:A5PLR1 psi-mi:vp24_ebozm(display_long)|uniprotkb:VP24(gene name)|psi-mi:VP24(display_short)|uniprotkb:Ebola VP24(gene name synonym) psi-mi:h31_human(display_long)|uniprotkb:H3FA(gene name synonym)|uniprotkb:H3FL(gene name synonym)|uniprotkb:H3FD(gene name synonym)|uniprotkb:H3FI(gene name synonym)|uniprotkb:H3FH(gene name synonym)|uniprotkb:H3FK(gene name synonym)|uniprotkb:H3FF(gene name synonym)|uniprotkb:H3FJ(gene name synonym)|uniprotkb:H3FB(gene name synonym)|uniprotkb:Histone H3/a(gene name synonym)|uniprotkb:Histone H3/b(gene name synonym)|uniprotkb:Histone H3/c(gene name synonym)|uniprotkb:Histone H3/d(gene name synonym)|uniprotkb:Histone H3/f(gene name synonym)|uniprotkb:Histone H3/h(gene name synonym)|uniprotkb:Histone H3/i(gene name synonym)|uniprotkb:Histone H3/j(gene name synonym)|uniprotkb:Histone H3/k(gene name synonym)|uniprotkb:Histone H3/l(gene name synonym)|uniprotkb:H3C1(gene name)|psi-mi:H3C1(display_short)|uniprotkb:HIST1H3A(gene name synonym)|uniprotkb:H3C2(gene name)|psi-mi:H3C2(display_short)|uniprotkb:HIST1H3B(gene name synonym)|uniprotkb:H3C3(gene name)|psi-mi:H3C3(display_short)|uniprotkb:H3FC HIST1H3C(gene name synonym)|uniprotkb:H3C4(gene name)|psi-mi:H3C4(display_short)|uniprotkb:HIST1H3D(gene name synonym)|uniprotkb:H3C6(gene name)|psi-mi:H3C6(display_short)|uniprotkb:HIST1H3E(gene name synonym)|uniprotkb:H3C7(gene name)|psi-mi:H3C7(display_short)|uniprotkb:HIST1H3F(gene name synonym)|uniprotkb:H3C8(gene name)|psi-mi:H3C8(display_short)|uniprotkb:HIST1H3G(gene name synonym)|uniprotkb:H3C10(gene name)|psi-mi:H3C10(display_short)|uniprotkb:HIST1H3H(gene name synonym)|uniprotkb:H3C11(gene name)|psi-mi:H3C11(display_short)|uniprotkb:HIST1H3I(gene name synonym)|uniprotkb:H3C12(gene name)|psi-mi:H3C12(display_short)|uniprotkb:HIST1H3J(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:128952(ebozm)|taxid:128952("Zaire ebolavirus (strain Mayinga-76)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159823|imex:IM-17331-68 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4U2X|rcsb pdb:4M0Q|interpro:IPR009433(Filovirus membrane-associated VP24)|refseq:NP_066250.1|rcsb pdb:6EHM|go:"GO:0005198"(structural molecule activity)|go:"GO:0016020"(membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0033645"(host cell endomembrane system)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0046774"(suppression by virus of host intracellular interferon activity)|go:"GO:0055036"(virion membrane) rcsb pdb:4TN7|rcsb pdb:4U68|rcsb pdb:4UP0|rcsb pdb:4UY4|rcsb pdb:4X3K|rcsb pdb:4Y6L|rcsb pdb:4YHP|rcsb pdb:4YHZ|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z0R|rcsb pdb:4Z2M|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:4QBS|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B31|rcsb pdb:5C11|rcsb pdb:5C13|rcsb pdb:5C3I|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5D6Y|rcsb pdb:5DAH|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5FFV|rcsb pdb:5GH9|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5HJB|rcsb pdb:5HJC|rcsb pdb:5HJD|rcsb pdb:5HYN|rcsb pdb:5IQL|rcsb pdb:5J3V|rcsb pdb:5J9S|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5B2J|rcsb pdb:5JRG|rcsb pdb:5KJH|rcsb pdb:5KJI|rcsb pdb:5KKL|rcsb pdb:5LUG|rcsb pdb:5M5G|rcsb pdb:5MR8|rcsb pdb:5NNC|rcsb pdb:5OY3|rcsb pdb:5SVX|rcsb pdb:5SVY|rcsb pdb:5SZB|rcsb pdb:5SZC|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5T1G|rcsb pdb:5T1I|rcsb pdb:5T8R|rcsb pdb:5TBN|rcsb pdb:5TDR|rcsb pdb:5TDW|rcsb pdb:5U2J|rcsb pdb:5V21|rcsb pdb:5V22|rcsb pdb:5VA6|rcsb pdb:5VAB|rcsb pdb:5VGE|rcsb pdb:5VNB|rcsb pdb:5NND|rcsb pdb:5WLE|rcsb pdb:5WVO|rcsb pdb:5WXG|rcsb pdb:5WXH|rcsb pdb:5WYI|rcsb pdb:5X60|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5XFQ|rcsb pdb:5XFR|rcsb pdb:5XNV|rcsb pdb:5XTZ|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Y20|rcsb pdb:5Y2F|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:6AXJ|rcsb pdb:6AZE|rcsb pdb:6BHD|rcsb pdb:6BHE|rcsb pdb:6BHG|rcsb pdb:6BHH|rcsb pdb:6BHI|rcsb pdb:6D07|rcsb pdb:6D08|rcsb pdb:6E83|rcsb pdb:6E86|rcsb pdb:5WFC|rcsb pdb:6F6D|rcsb pdb:6HTS|rcsb pdb:6IEU|rcsb pdb:6IIS|rcsb pdb:6IIT|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6LS6|rcsb pdb:6LSD|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MIL|rcsb pdb:6MIM|rcsb pdb:6MIN|rcsb pdb:6MIO|rcsb pdb:6MIQ|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6HKT|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2H|rcsb pdb:6V2K|rcsb pdb:6V3N|rcsb pdb:6V41|rcsb pdb:6V92|rcsb pdb:6VIL|rcsb pdb:6WAV|rcsb pdb:6WW4|rcsb pdb:6YIF|rcsb pdb:6YIH|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:6R92|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7KLR|rcsb pdb:7LYC|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|ensembl:ENSG00000197153(gene)|ensembl:ENSG00000197409(gene)|ensembl:ENSG00000273983(gene)|ensembl:ENSG00000274750(gene)|ensembl:ENSG00000275379(gene)|ensembl:ENSG00000275714(gene)|ensembl:ENSG00000277775(gene)|ensembl:ENSG00000278828(gene)|ensembl:ENSG00000286522(gene)|ensembl:ENSG00000287080(gene)|ensembl:ENST00000356476(transcript)|ensembl:ENST00000359303(transcript)|ensembl:ENST00000369163(transcript)|ensembl:ENST00000612966(transcript)|ensembl:ENST00000613854(transcript)|ensembl:ENST00000614378(transcript)|ensembl:ENST00000614911(transcript)|ensembl:ENST00000616365(transcript)|ensembl:ENST00000618052(transcript)|ensembl:ENST00000621411(transcript)|ensembl:ENST00000634733(transcript)|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-3247509|reactome:R-HSA-9710421|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060968"(obsolete regulation of gene silencing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|interpro:IPR009072(Histone-fold)|mint:P68431|rcsb pdb:1CS9|rcsb pdb:1CT6|rcsb pdb:1O9S|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|rcsb pdb:1Q3L|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|rcsb pdb:2B2T|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|rcsb pdb:2B2U|rcsb pdb:2B2V|rcsb pdb:2B2W|rcsb pdb:2C1J|rcsb pdb:2C1N|go:"GO:0016020"(membrane)|rcsb pdb:2CO0|rcsb pdb:2CV5|rcsb pdb:2FSA|rcsb pdb:2KWJ|rcsb pdb:2KWK|rcsb pdb:2L75|rcsb pdb:2LBM|rcsb pdb:2LGG|rcsb pdb:2M0O|reactome:R-HSA-983231|reactome:R-HSA-977225|rcsb pdb:2NDG|rcsb pdb:2OQ6|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2RI7|rcsb pdb:2RR4|rcsb pdb:2UXN|rcsb pdb:2V85|rcsb pdb:2V89|rcsb pdb:2VNF|rcsb pdb:2VPG|rcsb pdb:2X0L|rcsb pdb:3A1B|rcsb pdb:2NDF|rcsb pdb:3AFA|rcsb pdb:3AVR|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3B95|rcsb pdb:3FDT|rcsb pdb:3KMT|rcsb pdb:3KQI|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3MP1|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O37|rcsb pdb:3QJ6|rcsb pdb:3RIG|rcsb pdb:3RIY|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3U31|rcsb pdb:3U3D|rcsb pdb:3U4S|rcsb pdb:3U5N|rcsb pdb:3U5O|rcsb pdb:3AZK|rcsb pdb:3U5P|rcsb pdb:3UEE|rcsb pdb:3UEF|rcsb pdb:3UII|rcsb pdb:3UIK|rcsb pdb:3V43|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:3ZG6|rcsb pdb:3ZVY|rcsb pdb:4A0J|rcsb pdb:4A0N|rcsb pdb:4A7J|rcsb pdb:3UIG|rcsb pdb:4BD3|rcsb pdb:4C1Q|rcsb pdb:4F4U|rcsb pdb:4F56|rcsb pdb:4FWF|rcsb pdb:4HON|rcsb pdb:4I51|rcsb pdb:4L7X|rcsb pdb:4LK9|rcsb pdb:4LKA|rcsb pdb:4LLB|rcsb pdb:4LXL|rcsb pdb:4N4H|rcsb pdb:4QBQ|rcsb pdb:4QBR|refseq:NP_003520.1|refseq:NP_003521.2|refseq:NP_003522.1|refseq:NP_003523.1|refseq:NP_003524.1|refseq:NP_003525.1|refseq:NP_003526.1|refseq:NP_003527.1|refseq:NP_003528.1|refseq:NP_066298.1|dip:DIP-29371N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2020/10/21 rogid:XIBGYWZnAX/nJXjjgHl9gOSl0aQ128952 rogid:ood0OohxZHuhsWZtO7U7GMc+LwM9606 intact-crc:FF1F9421BD38EE29|rigid:qG7eOqc1UBjPMcIs8zn5a9Ck/xg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03070 uniprotkb:Q02539 intact:EBI-617698 intact:EBI-932603|uniprotkb:Q3MJ34|ensembl:ENSP00000244573 psi-mi:lt_sv40(display_long) psi-mi:h11_human(display_long)|uniprotkb:H1-1(gene name)|psi-mi:H1-1(display_short)|uniprotkb:H1F1(gene name synonym)|uniprotkb:HIST1H1A(gene name synonym)|uniprotkb:Histone H1a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:1891767(sv40)|taxid:1891767(sv40) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159937|imex:IM-17331-69 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0016787"(hydrolase activity)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039576"(suppression by virus of host JAK-STAT cascade via inhibition of JAK1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039686"(bidirectional double-stranded viral DNA replication)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR003133(T antigen, Ori-binding)|interpro:IPR010932(Large T antigen, polyomavirus, C-terminus)|interpro:IPR016392(Large T antigen, polyomaviridae)|interpro:IPR017910|interpro:IPR027417|interpro:IPR036869|rcsb pdb:1EJL|rcsb pdb:1GH6|rcsb pdb:1N25|rcsb pdb:1Q1S|rcsb pdb:1Q1T|rcsb pdb:1SVL|rcsb pdb:1SVM|rcsb pdb:1SVO|rcsb pdb:1TBD|rcsb pdb:1Z1D|rcsb pdb:2FUF|rcsb pdb:2H1L|rcsb pdb:2IF9|rcsb pdb:2IPR|rcsb pdb:2ITJ|rcsb pdb:2ITL|rcsb pdb:2NL8|rcsb pdb:2NTC|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|rcsb pdb:2TBD|rcsb pdb:3QK2|rcsb pdb:3QN2|rcsb pdb:4E2I|rcsb pdb:4FGN|rcsb pdb:4GDF|rcsb pdb:4RXH|rcsb pdb:5D9I|refseq:YP_003708382.1|mint:P03070|dip:DIP-24251N refseq:NP_005316.1|ensembl:ENSG00000124610(gene)|ensembl:ENST00000244573(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q02539|reactome:R-HSA-140342|reactome:R-HSA-2559584 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/10/18 rogid:IMcAp2PRxZXkbJ1eiXhJU9rD2JM1891767 rogid:4u8P8jFM3onWx43+SxL320urjhk9606 intact-crc:68AC3F2ABF7508B2|rigid:5qetIrfSRrCw2ybVmLd91ytNRAo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03070 uniprotkb:P04637 intact:EBI-617698 intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5 psi-mi:lt_sv40(display_long) psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:1891767(sv40)|taxid:1891767(sv40) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159937|imex:IM-17331-69 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0016787"(hydrolase activity)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039576"(suppression by virus of host JAK-STAT cascade via inhibition of JAK1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039686"(bidirectional double-stranded viral DNA replication)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR003133(T antigen, Ori-binding)|interpro:IPR010932(Large T antigen, polyomavirus, C-terminus)|interpro:IPR016392(Large T antigen, polyomaviridae)|interpro:IPR017910|interpro:IPR027417|interpro:IPR036869|rcsb pdb:1EJL|rcsb pdb:1GH6|rcsb pdb:1N25|rcsb pdb:1Q1S|rcsb pdb:1Q1T|rcsb pdb:1SVL|rcsb pdb:1SVM|rcsb pdb:1SVO|rcsb pdb:1TBD|rcsb pdb:1Z1D|rcsb pdb:2FUF|rcsb pdb:2H1L|rcsb pdb:2IF9|rcsb pdb:2IPR|rcsb pdb:2ITJ|rcsb pdb:2ITL|rcsb pdb:2NL8|rcsb pdb:2NTC|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|rcsb pdb:2TBD|rcsb pdb:3QK2|rcsb pdb:3QN2|rcsb pdb:4E2I|rcsb pdb:4FGN|rcsb pdb:4GDF|rcsb pdb:4RXH|rcsb pdb:5D9I|refseq:YP_003708382.1|mint:P03070|dip:DIP-24251N refseq:NP_001263624.1|refseq:NP_001263625.1|ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0043621"(protein self-association)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009651"(response to salt stress)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|interpro:IPR040926|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2AHI|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|mint:P04637|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:3Q06|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3SAK|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3TG5|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:4AGL|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:6XRE|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7EL4|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-983231|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5BUA|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6S3C|ensembl:ENSP00000269305|ensembl:ENST00000420246|ensembl:ENSP00000391127|ensembl:ENSP00000391478|ensembl:ENST00000455263|ensembl:ENSP00000398846|ensembl:ENST00000504290|ensembl:ENSP00000484409|ensembl:ENST00000504937|ensembl:ENSP00000481179|ensembl:ENST00000510385|ensembl:ENSP00000478499|ensembl:ENST00000610292|ensembl:ENSP00000478219|ensembl:ENST00000610538|ensembl:ENSP00000480868|ensembl:ENST00000619485|ensembl:ENSP00000482537|ensembl:ENST00000620739|ensembl:ENSP00000481638|ensembl:ENST00000622645|ensembl:ENSP00000482222|refseq:NP_001119590.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/10/18 rogid:IMcAp2PRxZXkbJ1eiXhJU9rD2JM1891767 rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606 intact-crc:68AC3F2ABF7508B2|rigid:5qetIrfSRrCw2ybVmLd91ytNRAo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03070 uniprotkb:P22492 intact:EBI-617698 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 psi-mi:lt_sv40(display_long) psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:1891767(sv40)|taxid:1891767(sv40) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159937|imex:IM-17331-69 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0016787"(hydrolase activity)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039576"(suppression by virus of host JAK-STAT cascade via inhibition of JAK1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039686"(bidirectional double-stranded viral DNA replication)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR003133(T antigen, Ori-binding)|interpro:IPR010932(Large T antigen, polyomavirus, C-terminus)|interpro:IPR016392(Large T antigen, polyomaviridae)|interpro:IPR017910|interpro:IPR027417|interpro:IPR036869|rcsb pdb:1EJL|rcsb pdb:1GH6|rcsb pdb:1N25|rcsb pdb:1Q1S|rcsb pdb:1Q1T|rcsb pdb:1SVL|rcsb pdb:1SVM|rcsb pdb:1SVO|rcsb pdb:1TBD|rcsb pdb:1Z1D|rcsb pdb:2FUF|rcsb pdb:2H1L|rcsb pdb:2IF9|rcsb pdb:2IPR|rcsb pdb:2ITJ|rcsb pdb:2ITL|rcsb pdb:2NL8|rcsb pdb:2NTC|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|rcsb pdb:2TBD|rcsb pdb:3QK2|rcsb pdb:3QN2|rcsb pdb:4E2I|rcsb pdb:4FGN|rcsb pdb:4GDF|rcsb pdb:4RXH|rcsb pdb:5D9I|refseq:YP_003708382.1|mint:P03070|dip:DIP-24251N refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/10/18 rogid:IMcAp2PRxZXkbJ1eiXhJU9rD2JM1891767 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 intact-crc:68AC3F2ABF7508B2|rigid:5qetIrfSRrCw2ybVmLd91ytNRAo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03070 uniprotkb:Q9UNE7 intact:EBI-617698 intact:EBI-357085|uniprotkb:O60526|uniprotkb:Q969U2|uniprotkb:Q9HBT1|uniprotkb:A2IDB9|ensembl:ENSP00000219548 psi-mi:lt_sv40(display_long) psi-mi:chip_human(display_long)|uniprotkb:CHIP(gene name synonym)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)|uniprotkb:PP1131(orf name)|uniprotkb:Carboxy terminus of Hsp70-interacting protein(gene name synonym)|uniprotkb:STIP1 homology and U box-containing protein 1(gene name synonym)|uniprotkb:CLL-associated antigen KW-8(gene name synonym)|uniprotkb:Antigen NY-CO-7(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHIP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:1891767(sv40)|taxid:1891767(sv40) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159937|imex:IM-17331-69 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0016787"(hydrolase activity)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039576"(suppression by virus of host JAK-STAT cascade via inhibition of JAK1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039686"(bidirectional double-stranded viral DNA replication)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR003133(T antigen, Ori-binding)|interpro:IPR010932(Large T antigen, polyomavirus, C-terminus)|interpro:IPR016392(Large T antigen, polyomaviridae)|interpro:IPR017910|interpro:IPR027417|interpro:IPR036869|rcsb pdb:1EJL|rcsb pdb:1GH6|rcsb pdb:1N25|rcsb pdb:1Q1S|rcsb pdb:1Q1T|rcsb pdb:1SVL|rcsb pdb:1SVM|rcsb pdb:1SVO|rcsb pdb:1TBD|rcsb pdb:1Z1D|rcsb pdb:2FUF|rcsb pdb:2H1L|rcsb pdb:2IF9|rcsb pdb:2IPR|rcsb pdb:2ITJ|rcsb pdb:2ITL|rcsb pdb:2NL8|rcsb pdb:2NTC|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|rcsb pdb:2TBD|rcsb pdb:3QK2|rcsb pdb:3QN2|rcsb pdb:4E2I|rcsb pdb:4FGN|rcsb pdb:4GDF|rcsb pdb:4RXH|rcsb pdb:5D9I|refseq:YP_003708382.1|mint:P03070|dip:DIP-24251N dip:DIP-29752N|refseq:NP_005852.2|refseq:NP_001280126.1|ensembl:ENSG00000103266(gene)|ensembl:ENST00000219548(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031943"(regulation of glucocorticoid metabolic process)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046332"(SMAD binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090035"(positive regulation of chaperone-mediated protein complex assembly)|go:"GO:0101031"(chaperone complex)|interpro:IPR003613(U box)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019734|interpro:IPR041312|mint:Q9UNE7|rcsb pdb:4KBQ|rcsb pdb:6EFK|rcsb pdb:6NSV|reactome:R-HSA-2173788|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-8939902|reactome:R-HSA-8948751|reactome:R-HSA-983168 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/10/18 rogid:IMcAp2PRxZXkbJ1eiXhJU9rD2JM1891767 rogid:h4QyIM0TptgkQppPUgiKn68XjP49606 intact-crc:68AC3F2ABF7508B2|rigid:5qetIrfSRrCw2ybVmLd91ytNRAo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03070 uniprotkb:O95816 intact:EBI-617698 intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407 psi-mi:lt_sv40(display_long) psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:1891767(sv40)|taxid:1891767(sv40) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159937|imex:IM-17331-69 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0016787"(hydrolase activity)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039576"(suppression by virus of host JAK-STAT cascade via inhibition of JAK1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039686"(bidirectional double-stranded viral DNA replication)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR003133(T antigen, Ori-binding)|interpro:IPR010932(Large T antigen, polyomavirus, C-terminus)|interpro:IPR016392(Large T antigen, polyomaviridae)|interpro:IPR017910|interpro:IPR027417|interpro:IPR036869|rcsb pdb:1EJL|rcsb pdb:1GH6|rcsb pdb:1N25|rcsb pdb:1Q1S|rcsb pdb:1Q1T|rcsb pdb:1SVL|rcsb pdb:1SVM|rcsb pdb:1SVO|rcsb pdb:1TBD|rcsb pdb:1Z1D|rcsb pdb:2FUF|rcsb pdb:2H1L|rcsb pdb:2IF9|rcsb pdb:2IPR|rcsb pdb:2ITJ|rcsb pdb:2ITL|rcsb pdb:2NL8|rcsb pdb:2NTC|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|rcsb pdb:2TBD|rcsb pdb:3QK2|rcsb pdb:3QN2|rcsb pdb:4E2I|rcsb pdb:4FGN|rcsb pdb:4GDF|rcsb pdb:4RXH|rcsb pdb:5D9I|refseq:YP_003708382.1|mint:P03070|dip:DIP-24251N refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/10/18 rogid:IMcAp2PRxZXkbJ1eiXhJU9rD2JM1891767 rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606 intact-crc:68AC3F2ABF7508B2|rigid:5qetIrfSRrCw2ybVmLd91ytNRAo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P03070 uniprotkb:P54652 intact:EBI-617698 intact:EBI-356991|uniprotkb:Q15508|uniprotkb:Q53XM3|uniprotkb:Q9UE78|ensembl:ENSP00000247207|ensembl:ENSP00000378199 psi-mi:lt_sv40(display_long) psi-mi:hsp72_human(display_long)|uniprotkb:HSPA2(gene name)|psi-mi:HSPA2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Pichlmair et al. (2012) pubmed:22810585|imex:IM-17331 taxid:1891767(sv40)|taxid:1891767(sv40) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159937|imex:IM-17331-69 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0016787"(hydrolase activity)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039576"(suppression by virus of host JAK-STAT cascade via inhibition of JAK1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039686"(bidirectional double-stranded viral DNA replication)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR003133(T antigen, Ori-binding)|interpro:IPR010932(Large T antigen, polyomavirus, C-terminus)|interpro:IPR016392(Large T antigen, polyomaviridae)|interpro:IPR017910|interpro:IPR027417|interpro:IPR036869|rcsb pdb:1EJL|rcsb pdb:1GH6|rcsb pdb:1N25|rcsb pdb:1Q1S|rcsb pdb:1Q1T|rcsb pdb:1SVL|rcsb pdb:1SVM|rcsb pdb:1SVO|rcsb pdb:1TBD|rcsb pdb:1Z1D|rcsb pdb:2FUF|rcsb pdb:2H1L|rcsb pdb:2IF9|rcsb pdb:2IPR|rcsb pdb:2ITJ|rcsb pdb:2ITL|rcsb pdb:2NL8|rcsb pdb:2NTC|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|rcsb pdb:2TBD|rcsb pdb:3QK2|rcsb pdb:3QN2|rcsb pdb:4E2I|rcsb pdb:4FGN|rcsb pdb:4GDF|rcsb pdb:4RXH|rcsb pdb:5D9I|refseq:YP_003708382.1|mint:P03070|dip:DIP-24251N refseq:NP_068814.2|ensembl:ENSG00000126803(gene)|ensembl:ENST00000247207(transcript)|ensembl:ENST00000394709(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0036128"(CatSper complex)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0048156"(tau protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051861"(glycolipid binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0072562"(blood microparticle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P54652|rcsb pdb:3I33|rcsb pdb:4FSV|rcsb pdb:5FPD|rcsb pdb:5FPE|rcsb pdb:5FPM|rcsb pdb:5FPN|reactome:R-HSA-1221632|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/06/15 2019/10/18 rogid:IMcAp2PRxZXkbJ1eiXhJU9rD2JM1891767 rogid:U+fdNfdxAWBQxDwSx0plk/iIBpM9606 intact-crc:68AC3F2ABF7508B2|rigid:5qetIrfSRrCw2ybVmLd91ytNRAo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification)