#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P53064 uniprotkb:Q06697 intact:EBI-16303|uniprotkb:P89115|ensemblfungi:YGL244W|uniprotkb:D6VV91 intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C psi-mi:rtf1_yeast(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:YGL244W(locus name)|uniprotkb:HRA458(orf name)|uniprotkb:CSL3(gene name synonym) psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7971889|mint:MINT-8404216|imex:IM-18582-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001160"(regulation of histone H3-K79 methylation)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR004343(Plus-3)|interpro:IPR036128|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|rcsb pdb:5E8B|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0042138"(meiotic DNA double-strand break formation)|rcsb pdb:5EMX|ensemblfungi:YGL244W(gene)|ensemblfungi:YGL244W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_011270.1|sgd:S000003213|dip:DIP-4065N|mint:P53064|mint:MINT-8404219(identity) refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8404218(identity) - crc64:13AECCEC6D63CED4 crc64:9580B53EEFB75345 figure legend:f4a sf10c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2012/12/11 2014/10/16 rogid:jPawNxTgh9wPA5Uxbn5QCUeDw9Q559292 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 intact-crc:D3C53A853B9C511F|rigid:+tCW0wNi4swOppJb4FCQTIwQlcI false - myc tag:?-?(MINT-8404223) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P38351 uniprotkb:Q06697 intact:EBI-12855|uniprotkb:Q9URC9|uniprotkb:D6VQS4|ensemblfungi:YBR279W intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C psi-mi:paf1_yeast(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:YBR279W(locus name)|uniprotkb:YBR2016(orf name)|uniprotkb:Protein PAF1(gene name synonym) psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7971926|mint:MINT-8404227|imex:IM-18582-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBR279W(gene)|ensemblfungi:YBR279W_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006364"(rRNA processing)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|rcsb pdb:5ZYP|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_009838.1|sgd:S000000483|mint:P38351|dip:DIP-1149N|mint:MINT-8404229(identity) refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8404231(identity) - - crc64:9580B53EEFB75345 figure legend:sf4b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2012/12/11 2014/10/16 rogid:k4kVCyYuA4w4+4OEroTkwhbxs6Q559292 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 intact-crc:CA64BC30D476F5D5|rigid:4PuO8GAUoFfImxZy6LjaRfL71Jg false ha tag:?-?(MINT-8404237) myc tag:?-?(MINT-8404232) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P04050 uniprotkb:P53064 intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C intact:EBI-16303|uniprotkb:P89115|ensemblfungi:YGL244W|uniprotkb:D6VV91 psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:rtf1_yeast(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:YGL244W(locus name)|uniprotkb:HRA458(orf name)|uniprotkb:CSL3(gene name synonym) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7971950|mint:MINT-8404540|imex:IM-18582-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8404543(identity) go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001160"(regulation of histone H3-K79 methylation)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR004343(Plus-3)|interpro:IPR036128|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|rcsb pdb:5E8B|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0042138"(meiotic DNA double-strand break formation)|rcsb pdb:5EMX|ensemblfungi:YGL244W(gene)|ensemblfungi:YGL244W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_011270.1|sgd:S000003213|dip:DIP-4065N|mint:P53064|mint:MINT-8404542(identity) - crc64:A45C1360FF99F968 crc64:13AECCEC6D63CED4 figure legend:f1a f1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 rogid:jPawNxTgh9wPA5Uxbn5QCUeDw9Q559292 intact-crc:09F67795783A0FF2|rigid:iYO39ltGcqX6M4qCfjW8a3OM3TQ false binding-associated region:1556-1576(MINT-8404736)|mutation disrupting interaction:1557-1557(MINT-8404799)|phosphorylated residue:1560-1560(MINT-8404740)|phosphorylated residue:1557-1557(MINT-8404738)|mutation disrupting interaction:1560-1560(MINT-8404796)|biotin tag:?-?(MINT-8404655) - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P04050 uniprotkb:P53064 intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C intact:EBI-16303|uniprotkb:P89115|ensemblfungi:YGL244W|uniprotkb:D6VV91 psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:rtf1_yeast(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:YGL244W(locus name)|uniprotkb:HRA458(orf name)|uniprotkb:CSL3(gene name synonym) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7971982|mint:MINT-8404743|imex:IM-18582-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8404747(identity) go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001160"(regulation of histone H3-K79 methylation)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR004343(Plus-3)|interpro:IPR036128|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|rcsb pdb:5E8B|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0042138"(meiotic DNA double-strand break formation)|rcsb pdb:5EMX|ensemblfungi:YGL244W(gene)|ensemblfungi:YGL244W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_011270.1|sgd:S000003213|dip:DIP-4065N|mint:P53064|mint:MINT-8404745(identity) - crc64:A45C1360FF99F968 crc64:13AECCEC6D63CED4 figure legend:f1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 rogid:jPawNxTgh9wPA5Uxbn5QCUeDw9Q559292 intact-crc:F98E11C04AF30AC1|rigid:iYO39ltGcqX6M4qCfjW8a3OM3TQ false phosphorylated residue:1560-1560(MINT-8404748)|biotin tag:?-?(MINT-8404754)|binding-associated region:1556-1576(MINT-8404752)|phosphorylated residue:1562-1562(MINT-8404750) - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P04050 uniprotkb:Q06697 intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7972033|mint:MINT-8404777|imex:IM-18582-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8404783(identity) refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8404779(identity) - crc64:A45C1360FF99F968 crc64:9580B53EEFB75345 figure legend:f1a sf10a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 intact-crc:FA742FA83AAF7FCA|rigid:n7RYYoXvdKqBAvpo833pbhA8W1Y false phosphorylated residue:1560-1560(MINT-8404784)|phosphorylated residue:1557-1557(MINT-8404786)|binding-associated region:1556-1576(MINT-8404788)|biotin tag:?-?(MINT-8404790) tag:?-?(MINT-8404780) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P04050 uniprotkb:Q06697 intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7972006|mint:MINT-8404759|imex:IM-18582-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8404761(identity) refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8404771(identity) - crc64:A45C1360FF99F968 crc64:9580B53EEFB75345 figure legend:f1a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 intact-crc:829D49AE54987141|rigid:n7RYYoXvdKqBAvpo833pbhA8W1Y false biotin tag:?-?(MINT-8404762)|phosphorylated residue:1562-1562(MINT-8404766)|phosphorylated residue:1560-1560(MINT-8404768)|binding-associated region:1556-1576(MINT-8404764) tag:?-?(MINT-8404774) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P53064 uniprotkb:P04050 intact:EBI-16303|uniprotkb:P89115|ensemblfungi:YGL244W|uniprotkb:D6VV91 intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C psi-mi:rtf1_yeast(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:YGL244W(locus name)|uniprotkb:HRA458(orf name)|uniprotkb:CSL3(gene name synonym) psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7972077|mint:MINT-8404803|imex:IM-18582-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001160"(regulation of histone H3-K79 methylation)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR004343(Plus-3)|interpro:IPR036128|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|rcsb pdb:5E8B|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0042138"(meiotic DNA double-strand break formation)|rcsb pdb:5EMX|ensemblfungi:YGL244W(gene)|ensemblfungi:YGL244W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_011270.1|sgd:S000003213|dip:DIP-4065N|mint:P53064|mint:MINT-8404805(identity) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8404807(identity) - crc64:13AECCEC6D63CED4 crc64:A45C1360FF99F968 figure legend:f1c f1d sf2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:jPawNxTgh9wPA5Uxbn5QCUeDw9Q559292 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 intact-crc:6DE100C43D6A9634|rigid:iYO39ltGcqX6M4qCfjW8a3OM3TQ false glutathione s tranferase tag:?-?(MINT-8404824) binding-associated region:1556-1576(MINT-8404816)|biotin tag:?-?(MINT-8404818)|mutation disrupting interaction:1560-1560(MINT-8404810)|phosphorylated residue:1557-1557(MINT-8404814)|mutation disrupting interaction:1557-1557(MINT-8404808)|phosphorylated residue:1560-1560(MINT-8404812) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:P04050 uniprotkb:Q06697 intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7972143|mint:MINT-8404829|imex:IM-18582-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8404831(identity) refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8404841(identity) - crc64:A45C1360FF99F968 crc64:9580B53EEFB75345 figure legend:f1c sf2 sf11b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 intact-crc:4B9CBC18D6EE7049|rigid:n7RYYoXvdKqBAvpo833pbhA8W1Y false mutation decreasing interaction:1560-1560(MINT-8405639)|biotin tag:?-?(MINT-8404832)|mutation decreasing interaction:1557-1557(MINT-8405641)|phosphorylated residue:1560-1560(MINT-8404838)|phosphorylated residue:1557-1557(MINT-8404836)|binding-associated region:1556-1576(MINT-8404834) glutathione s tranferase tag:?-?(MINT-8404842) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P04050 uniprotkb:Q06697 intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7972229|mint:MINT-8404848|imex:IM-18582-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8404854(identity) refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8404850(identity) - crc64:A45C1360FF99F968 crc64:9580B53EEFB75345 figure legend:sf2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 intact-crc:760EB34566079C0A|rigid:n7RYYoXvdKqBAvpo833pbhA8W1Y false phosphorylated residue:1562-1562(MINT-8404857)|biotin tag:?-?(MINT-8404861)|phosphorylated residue:1560-1560(MINT-8404855)|binding-associated region:1556-1576(MINT-8404859) glutathione s tranferase tag:?-?(MINT-8404851) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P04050 uniprotkb:Q06697 intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7972256|mint:MINT-8404867|imex:IM-18582-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8404869(identity) refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8404879(identity) - crc64:A45C1360FF99F968 crc64:9580B53EEFB75345 figure legend:sf2b f1c sf11b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 intact-crc:22CB87D6C9BEA45E|rigid:n7RYYoXvdKqBAvpo833pbhA8W1Y false phosphorylated residue:1560-1560(MINT-8404876)|binding-associated region:1556-1576(MINT-8404872)|biotin tag:?-?(MINT-8404870)|mutation decreasing interaction:1560-1560(MINT-8405634) glutathione s tranferase tag:?-?(MINT-8404880) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q06697 uniprotkb:P04050 intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7972283|mint:MINT-8404886|imex:IM-18582-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8404888(identity) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8404892(identity) - crc64:9580B53EEFB75345 crc64:A45C1360FF99F968 figure legend:sf2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 intact-crc:1543CFE59C691334|rigid:n7RYYoXvdKqBAvpo833pbhA8W1Y false glutathione s tranferase tag:?-?(MINT-8404889) binding-associated region:1556-1576(MINT-8404895)|biotin tag:?-?(MINT-8404897)|phosphorylated residue:1562-1562(MINT-8404893) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q06697 uniprotkb:P04050 intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7972306|mint:MINT-8404902|imex:IM-18582-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8404912(identity) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8404904(identity) - crc64:9580B53EEFB75345 crc64:A45C1360FF99F968 figure legend:sf2b f1c sf11b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 intact-crc:5854A09BFE4331AE|rigid:n7RYYoXvdKqBAvpo833pbhA8W1Y false glutathione s tranferase tag:?-?(MINT-8404913) phosphorylated residue:1557-1557(MINT-8404909)|binding-associated region:1556-1576(MINT-8404907)|biotin tag:?-?(MINT-8404905) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:P04050 uniprotkb:P89105 intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C intact:EBI-5283|uniprotkb:O14409|uniprotkb:Q07332|uniprotkb:Q08292|uniprotkb:D6W1S4|ensemblfungi:YOL145C psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:ctr9_yeast(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:CDP1(gene name synonym)|uniprotkb:Cln three-requiring protein 9(gene name synonym)|uniprotkb:Centromere-binding factor 1-dependent protein 1(gene name synonym)|uniprotkb:YOL145C(locus name) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7972329|mint:MINT-8404921|imex:IM-18582-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8404927(identity) refseq:NP_014496.2|sgd:S000005505|dip:DIP-2814N|mint:P89105|ensemblfungi:YOL145C(gene)|ensemblfungi:YOL145C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0035327"|go:"GO:0045142"(triplex DNA binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|rcsb pdb:5ZYP|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8404923(identity) - crc64:A45C1360FF99F968 crc64:F794ECBAD26D4820 figure legend:sf2 f1d f1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 rogid:85qAqldtQL8T7JBgNxrvAYtHhd0559292 intact-crc:DBCC2F883808C6FF|rigid:gZmzcaBULZYEPoIGQMFGBnhj4eI false biotin tag:?-?(MINT-8404932)|phosphorylated residue:1560-1560(MINT-8404928)|binding-associated region:1556-1576(MINT-8404930) glutathione s tranferase tag:?-?(MINT-8404924)|binding-associated region:594-855(MINT-8404938) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P04050 uniprotkb:P89105 intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C intact:EBI-5283|uniprotkb:O14409|uniprotkb:Q07332|uniprotkb:Q08292|uniprotkb:D6W1S4|ensemblfungi:YOL145C psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:ctr9_yeast(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:CDP1(gene name synonym)|uniprotkb:Cln three-requiring protein 9(gene name synonym)|uniprotkb:Centromere-binding factor 1-dependent protein 1(gene name synonym)|uniprotkb:YOL145C(locus name) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7972372|mint:MINT-8404941|imex:IM-18582-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8404949(identity) refseq:NP_014496.2|sgd:S000005505|dip:DIP-2814N|mint:P89105|ensemblfungi:YOL145C(gene)|ensemblfungi:YOL145C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0035327"|go:"GO:0045142"(triplex DNA binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|rcsb pdb:5ZYP|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8404943(identity) - crc64:A45C1360FF99F968 crc64:F794ECBAD26D4820 figure legend:sf2 f1d f1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 rogid:85qAqldtQL8T7JBgNxrvAYtHhd0559292 intact-crc:100C5922B99C2458|rigid:gZmzcaBULZYEPoIGQMFGBnhj4eI false phosphorylated residue:1557-1557(MINT-8404958)|biotin tag:?-?(MINT-8404950)|phosphorylated residue:1560-1560(MINT-8404954)|binding-associated region:1556-1576(MINT-8404952) binding-associated region:594-855(MINT-8404944)|glutathione s tranferase tag:?-?(MINT-8404946) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P89105 uniprotkb:P04050 intact:EBI-5283|uniprotkb:O14409|uniprotkb:Q07332|uniprotkb:Q08292|uniprotkb:D6W1S4|ensemblfungi:YOL145C intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C psi-mi:ctr9_yeast(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:CDP1(gene name synonym)|uniprotkb:Cln three-requiring protein 9(gene name synonym)|uniprotkb:Centromere-binding factor 1-dependent protein 1(gene name synonym)|uniprotkb:YOL145C(locus name) psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7972432|mint:MINT-8404983|imex:IM-18582-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014496.2|sgd:S000005505|dip:DIP-2814N|mint:P89105|ensemblfungi:YOL145C(gene)|ensemblfungi:YOL145C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0035327"|go:"GO:0045142"(triplex DNA binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|rcsb pdb:5ZYP|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8404985(identity) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8404991(identity) - crc64:F794ECBAD26D4820 crc64:A45C1360FF99F968 figure legend:f1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:85qAqldtQL8T7JBgNxrvAYtHhd0559292 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 intact-crc:48C7812B6B7CD066|rigid:gZmzcaBULZYEPoIGQMFGBnhj4eI false glutathione s tranferase tag:?-?(MINT-8404988)|binding-associated region:594-855(MINT-8404986) binding-associated region:1556-1576(MINT-8404994)|phosphorylated residue:1557-1557(MINT-8404996)|biotin tag:?-?(MINT-8404992) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:P04050 uniprotkb:P89105 intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C intact:EBI-5283|uniprotkb:O14409|uniprotkb:Q07332|uniprotkb:Q08292|uniprotkb:D6W1S4|ensemblfungi:YOL145C psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:ctr9_yeast(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:CDP1(gene name synonym)|uniprotkb:Cln three-requiring protein 9(gene name synonym)|uniprotkb:Centromere-binding factor 1-dependent protein 1(gene name synonym)|uniprotkb:YOL145C(locus name) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7972402|mint:MINT-8404961|imex:IM-18582-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8404963(identity) refseq:NP_014496.2|sgd:S000005505|dip:DIP-2814N|mint:P89105|ensemblfungi:YOL145C(gene)|ensemblfungi:YOL145C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0035327"|go:"GO:0045142"(triplex DNA binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|rcsb pdb:5ZYP|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8404973(identity) - crc64:A45C1360FF99F968 crc64:F794ECBAD26D4820 figure legend:sf2 f1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 rogid:85qAqldtQL8T7JBgNxrvAYtHhd0559292 intact-crc:B490E36FEC684865|rigid:gZmzcaBULZYEPoIGQMFGBnhj4eI false biotin tag:?-?(MINT-8404970)|phosphorylated residue:1560-1560(MINT-8404966)|binding-associated region:1556-1576(MINT-8404968)|phosphorylated residue:1562-1562(MINT-8404964) binding-associated region:594-855(MINT-8404976)|glutathione s tranferase tag:?-?(MINT-8404974) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P04050 uniprotkb:P53064 intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C intact:EBI-16303|uniprotkb:P89115|ensemblfungi:YGL244W|uniprotkb:D6VV91 psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:rtf1_yeast(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:YGL244W(locus name)|uniprotkb:HRA458(orf name)|uniprotkb:CSL3(gene name synonym) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7972458|mint:MINT-8405004|imex:IM-18582-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8405008(identity) go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001160"(regulation of histone H3-K79 methylation)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR004343(Plus-3)|interpro:IPR036128|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|rcsb pdb:5E8B|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0042138"(meiotic DNA double-strand break formation)|rcsb pdb:5EMX|ensemblfungi:YGL244W(gene)|ensemblfungi:YGL244W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_011270.1|sgd:S000003213|dip:DIP-4065N|mint:P53064|mint:MINT-8405006(identity) - crc64:A45C1360FF99F968 crc64:13AECCEC6D63CED4 figure legend:f1a f1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 rogid:jPawNxTgh9wPA5Uxbn5QCUeDw9Q559292 intact-crc:F940163C7C23D1B5|rigid:iYO39ltGcqX6M4qCfjW8a3OM3TQ false binding-associated region:1556-1576(MINT-8405017)|phosphorylated residue:1560-1560(MINT-8405013)|mutation disrupting interaction:1557-1557(MINT-8405009)|phosphorylated residue:1557-1557(MINT-8405015)|mutation disrupting interaction:1560-1560(MINT-8405011)|biotin tag:?-?(MINT-8405019) - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P04050 uniprotkb:P53064 intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C intact:EBI-16303|uniprotkb:P89115|ensemblfungi:YGL244W|uniprotkb:D6VV91 psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:rtf1_yeast(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:YGL244W(locus name)|uniprotkb:HRA458(orf name)|uniprotkb:CSL3(gene name synonym) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7972490|mint:MINT-8405023|imex:IM-18582-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8405027(identity) go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001160"(regulation of histone H3-K79 methylation)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR004343(Plus-3)|interpro:IPR036128|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|rcsb pdb:5E8B|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0042138"(meiotic DNA double-strand break formation)|rcsb pdb:5EMX|ensemblfungi:YGL244W(gene)|ensemblfungi:YGL244W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_011270.1|sgd:S000003213|dip:DIP-4065N|mint:P53064|mint:MINT-8405025(identity) - crc64:A45C1360FF99F968 crc64:13AECCEC6D63CED4 figure legend:sf2e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 rogid:jPawNxTgh9wPA5Uxbn5QCUeDw9Q559292 intact-crc:996001796B2B7312|rigid:iYO39ltGcqX6M4qCfjW8a3OM3TQ false phosphorylated residue:1557-1557(MINT-8405034)|biotin tag:?-?(MINT-8405038)|binding-associated region:1556-1576(MINT-8405036)|phosphorylated residue:1560-1560(MINT-8405032) tag:?-?(MINT-8405043) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P27692 uniprotkb:P53064 intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W intact:EBI-16303|uniprotkb:P89115|ensemblfungi:YGL244W|uniprotkb:D6VV91 psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:rtf1_yeast(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:YGL244W(locus name)|uniprotkb:HRA458(orf name)|uniprotkb:CSL3(gene name synonym) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7972534|mint:MINT-8405047|imex:IM-18582-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692|mint:MINT-8405049(identity) go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001160"(regulation of histone H3-K79 methylation)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR004343(Plus-3)|interpro:IPR036128|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|rcsb pdb:5E8B|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0042138"(meiotic DNA double-strand break formation)|rcsb pdb:5EMX|ensemblfungi:YGL244W(gene)|ensemblfungi:YGL244W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_011270.1|sgd:S000003213|dip:DIP-4065N|mint:P53064|mint:MINT-8405059(identity) - crc64:E4324DB6B1E4721A crc64:13AECCEC6D63CED4 figure legend:sf2f sf11c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 rogid:jPawNxTgh9wPA5Uxbn5QCUeDw9Q559292 intact-crc:CC22475819C6ACFF|rigid:PoPaICcZEQSXtnZJrwYOi8xtkqY false phosphorylated residue:1-1(MINT-8405056)|phosphorylated residue:7-7(MINT-8405054)|mutation decreasing interaction:7-7(MINT-8405072)|phosphorylated residue:13-13(MINT-8405065)|phosphorylated residue:19-19(MINT-8405067)|mutation decreasing interaction:19-19(MINT-8405078)|biotin tag:?-?(MINT-8405050)|mutation decreasing interaction:13-13(MINT-8405075)|binding-associated region:?-?(MINT-8405052)|mutation decreasing interaction:1-1(MINT-8405069) tag:?-?(MINT-8405060) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P53064 uniprotkb:P27692 intact:EBI-16303|uniprotkb:P89115|ensemblfungi:YGL244W|uniprotkb:D6VV91 intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W psi-mi:rtf1_yeast(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:YGL244W(locus name)|uniprotkb:HRA458(orf name)|uniprotkb:CSL3(gene name synonym) psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7972588|mint:MINT-8405084|imex:IM-18582-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001160"(regulation of histone H3-K79 methylation)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR004343(Plus-3)|interpro:IPR036128|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|rcsb pdb:5E8B|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0042138"(meiotic DNA double-strand break formation)|rcsb pdb:5EMX|ensemblfungi:YGL244W(gene)|ensemblfungi:YGL244W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_011270.1|sgd:S000003213|dip:DIP-4065N|mint:P53064|mint:MINT-8405108(identity) refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692|mint:MINT-8405086(identity) - crc64:13AECCEC6D63CED4 crc64:E4324DB6B1E4721A figure legend:f2a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:jPawNxTgh9wPA5Uxbn5QCUeDw9Q559292 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 intact-crc:8392779BF3D069C2|rigid:PoPaICcZEQSXtnZJrwYOi8xtkqY false - phosphorylated residue:7-7(MINT-8405101)|phosphorylated residue:19-19(MINT-8405095)|biotin tag:?-?(MINT-8405105)|binding-associated region:?-?(MINT-8405103)|phosphorylated residue:13-13(MINT-8405097)|mutation decreasing interaction:19-19(MINT-8405087)|mutation decreasing interaction:13-13(MINT-8405089)|phosphorylated residue:1-1(MINT-8405099)|mutation decreasing interaction:1-1(MINT-8405093)|mutation decreasing interaction:7-7(MINT-8405091) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:P27692 uniprotkb:Q06697 intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7972690|mint:MINT-8405148|imex:IM-18582-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692|mint:MINT-8405152(identity) refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8405150(identity) - crc64:E4324DB6B1E4721A crc64:9580B53EEFB75345 figure legend:f2b f2c f2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 intact-crc:4625E26B58AA8212|rigid:ZhxmI4zmnXc8C0equWwIQ3xw6x4 false phosphorylated residue:19-19(MINT-8405161)|biotin tag:?-?(MINT-8405171)|phosphorylated residue:13-13(MINT-8405163)|phosphorylated residue:1-1(MINT-8405165)|phosphorylated residue:7-7(MINT-8405167)|binding-associated region:?-?(MINT-8405169) glutathione s tranferase tag:?-?(MINT-8405219) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P27692 uniprotkb:Q06697 intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7972639|mint:MINT-8405115|imex:IM-18582-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692|mint:MINT-8405119(identity) refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8405117(identity) - crc64:E4324DB6B1E4721A crc64:9580B53EEFB75345 figure legend:f2a sf10a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 intact-crc:F7F39BB50083F0AF|rigid:ZhxmI4zmnXc8C0equWwIQ3xw6x4 false mutation decreasing interaction:7-7(MINT-8405134)|binding-associated region:?-?(MINT-8405122)|phosphorylated residue:13-13(MINT-8405128)|biotin tag:?-?(MINT-8405120)|phosphorylated residue:19-19(MINT-8405130)|phosphorylated residue:1-1(MINT-8405126)|mutation decreasing interaction:19-19(MINT-8405138)|phosphorylated residue:7-7(MINT-8405124)|mutation decreasing interaction:13-13(MINT-8405136)|mutation decreasing interaction:1-1(MINT-8405132) - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P89105 uniprotkb:P27692 intact:EBI-5283|uniprotkb:O14409|uniprotkb:Q07332|uniprotkb:Q08292|uniprotkb:D6W1S4|ensemblfungi:YOL145C intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W psi-mi:ctr9_yeast(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:CDP1(gene name synonym)|uniprotkb:Cln three-requiring protein 9(gene name synonym)|uniprotkb:Centromere-binding factor 1-dependent protein 1(gene name synonym)|uniprotkb:YOL145C(locus name) psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7972728|mint:MINT-8405175|imex:IM-18582-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014496.2|sgd:S000005505|dip:DIP-2814N|mint:P89105|ensemblfungi:YOL145C(gene)|ensemblfungi:YOL145C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0035327"|go:"GO:0045142"(triplex DNA binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|rcsb pdb:5ZYP|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8405185(identity) refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692|mint:MINT-8405177(identity) - crc64:F794ECBAD26D4820 crc64:E4324DB6B1E4721A figure legend:f1c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:85qAqldtQL8T7JBgNxrvAYtHhd0559292 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 intact-crc:DAFD8228CE689AE4|rigid:LeCCQCmY4bAE6MrZuTRYZfT0JwA false glutathione s tranferase tag:?-?(MINT-8405186)|binding-associated region:594-855(MINT-8405188) phosphorylated residue:7-7(MINT-8405229)|phosphorylated residue:1-1(MINT-8405178)|biotin tag:?-?(MINT-8405182)|phosphorylated residue:19-19(MINT-8405233)|phosphorylated residue:13-13(MINT-8405231) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:P53064 uniprotkb:P27692 intact:EBI-16303|uniprotkb:P89115|ensemblfungi:YGL244W|uniprotkb:D6VV91 intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W psi-mi:rtf1_yeast(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:YGL244W(locus name)|uniprotkb:HRA458(orf name)|uniprotkb:CSL3(gene name synonym) psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7972780|mint:MINT-8405192|imex:IM-18582-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001160"(regulation of histone H3-K79 methylation)|go:"GO:2001163"(regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001166"(regulation of histone H2B ubiquitination)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR004343(Plus-3)|interpro:IPR036128|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|rcsb pdb:5E8B|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0042138"(meiotic DNA double-strand break formation)|rcsb pdb:5EMX|ensemblfungi:YGL244W(gene)|ensemblfungi:YGL244W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001015"(snoRNA transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|reactome:R-SCE-674695|reactome:R-SCE-75955|refseq:NP_011270.1|sgd:S000003213|dip:DIP-4065N|mint:P53064|mint:MINT-8405194(identity) refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692|mint:MINT-8405196(identity) - crc64:13AECCEC6D63CED4 crc64:E4324DB6B1E4721A figure legend:f2b f2c f2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:jPawNxTgh9wPA5Uxbn5QCUeDw9Q559292 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 intact-crc:887A5A347B5A31D1|rigid:PoPaICcZEQSXtnZJrwYOi8xtkqY false glutathione s tranferase tag:?-?(MINT-8405226) phosphorylated residue:13-13(MINT-8405205)|phosphorylated residue:1-1(MINT-8405203)|biotin tag:?-?(MINT-8405197)|phosphorylated residue:19-19(MINT-8405207)|phosphorylated residue:7-7(MINT-8405201)|binding-associated region:?-?(MINT-8405199) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q06697 uniprotkb:P04050 intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7972818|mint:MINT-8405236|imex:IM-18582-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8405238(identity) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8405242(identity) - crc64:9580B53EEFB75345 crc64:A45C1360FF99F968 figure legend:f3a f3b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 intact-crc:39284BBFD368C4F7|rigid:n7RYYoXvdKqBAvpo833pbhA8W1Y false mutation disrupting interaction:380-380(MINT-8405401)|binding-associated region:201-393(MINT-8405399)|mutation disrupting interaction:357-357(MINT-8405403)|glutathione s tranferase tag:?-?(MINT-8405239) binding-associated region:1556-1576(MINT-8405247)|phosphorylated residue:1557-1557(MINT-8405245)|biotin tag:?-?(MINT-8405249) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:P27692 uniprotkb:Q06697 intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7972852|mint:MINT-8405280|imex:IM-18582-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692|mint:MINT-8405282(identity) refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8405304(identity) - crc64:E4324DB6B1E4721A crc64:9580B53EEFB75345 figure legend:f3D sf10b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 intact-crc:21F7B12DCD339493|rigid:ZhxmI4zmnXc8C0equWwIQ3xw6x4 false phosphorylated residue:19-19(MINT-8405293)|phosphorylated residue:7-7(MINT-8405287)|phosphorylated residue:1-1(MINT-8405289)|phosphorylated residue:13-13(MINT-8405291)|biotin tag:?-?(MINT-8405283) mutation disrupting interaction:380-380(MINT-8405314)|binding-associated region:201-393(MINT-8405312)|glutathione s tranferase tag:?-?(MINT-8405310)|mutation disrupting interaction:357-357(MINT-8405317) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:Q06697 uniprotkb:P27692 intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7972895|mint:MINT-8405321|imex:IM-18582-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8405323(identity) refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692|mint:MINT-8405333(identity) - crc64:9580B53EEFB75345 crc64:E4324DB6B1E4721A figure legend:f3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 intact-crc:8162BF72CCDDAEF1|rigid:ZhxmI4zmnXc8C0equWwIQ3xw6x4 false glutathione s tranferase tag:?-?(MINT-8405330)|binding-associated region:201-393(MINT-8405328)|mutation disrupting interaction:380-380(MINT-8405326) phosphorylated residue:13-13(MINT-8405336)|phosphorylated residue:1-1(MINT-8405338)|biotin tag:?-?(MINT-8405342)|phosphorylated residue:19-19(MINT-8405334)|phosphorylated residue:7-7(MINT-8405340) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:P27692 uniprotkb:Q06697 intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7972982|mint:MINT-8405347|imex:IM-18582-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692|mint:MINT-8405349(identity) refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8405361(identity) - crc64:E4324DB6B1E4721A crc64:9580B53EEFB75345 figure legend:f3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 intact-crc:F7261A4E4D3F8B08|rigid:ZhxmI4zmnXc8C0equWwIQ3xw6x4 false phosphorylated residue:7-7(MINT-8405352)|biotin tag:?-?(MINT-8405350)|phosphorylated residue:19-19(MINT-8405358)|phosphorylated residue:1-1(MINT-8405354)|phosphorylated residue:13-13(MINT-8405356) glutathione s tranferase tag:?-?(MINT-8405362)|binding-associated region:201-393(MINT-8405364)|mutation disrupting interaction:254-261(MINT-8405366) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P27692 uniprotkb:Q06697 intact:EBI-17937|uniprotkb:D6VZG4|ensemblfungi:YML010W intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C psi-mi:spt5_yeast(display_long)|uniprotkb:SPT5(gene name)|psi-mi:SPT5(display_short)|uniprotkb:YML010W(locus name)|uniprotkb:YM9571.08(orf name)|uniprotkb:Chromatin elongation factor SPT5(gene name synonym) psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7973021|mint:MINT-8405372|imex:IM-18582-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013703.1|sgd:S000004470|ensemblfungi:YML010W(gene)|ensemblfungi:YML010W_mRNA(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070990"(snRNP binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2001208"(negative regulation of transcription elongation by RNA polymerase I)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|rcsb pdb:2EXU|rcsb pdb:4YTK|rcsb pdb:4YTL|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6796648|reactome:R-SCE-72086|reactome:R-SCE-75955|reactome:R-SCE-77075|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|dip:DIP-6621N|mint:P27692|mint:MINT-8405382(identity) refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8405374(identity) - crc64:E4324DB6B1E4721A crc64:9580B53EEFB75345 figure legend:f3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:5atgyJBgDNSv1Jlg+SpCuA45MjU559292 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 intact-crc:3F20CF44B2608D72|rigid:ZhxmI4zmnXc8C0equWwIQ3xw6x4 false phosphorylated residue:7-7(MINT-8405389)|phosphorylated residue:13-13(MINT-8405385)|biotin tag:?-?(MINT-8405391)|phosphorylated residue:1-1(MINT-8405387)|phosphorylated residue:19-19(MINT-8405383) binding-associated region:201-393(MINT-8405377)|glutathione s tranferase tag:?-?(MINT-8405379)|mutation decreasing interaction:304-309(MINT-8405375) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:Q06697 uniprotkb:P04050 intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7973060|mint:MINT-8405406|imex:IM-18582-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8405416(identity) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8405408(identity) - crc64:9580B53EEFB75345 crc64:A45C1360FF99F968 figure legend:f3a f3b sf10b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 intact-crc:7843295F69100907|rigid:n7RYYoXvdKqBAvpo833pbhA8W1Y false glutathione s tranferase tag:?-?(MINT-8405423)|binding-associated region:201-393(MINT-8405421)|mutation disrupting interaction:380-380(MINT-8405419) phosphorylated residue:1557-1557(MINT-8405413)|binding-associated region:1556-1576(MINT-8405411)|biotin tag:?-?(MINT-8405409) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:P04050 uniprotkb:Q06697 intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7973090|mint:MINT-8405428|imex:IM-18582-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8405438(identity) refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8405430(identity) - crc64:A45C1360FF99F968 crc64:9580B53EEFB75345 figure legend:f3b f3a sf10b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 intact-crc:16FE27B5AE5FC9AE|rigid:n7RYYoXvdKqBAvpo833pbhA8W1Y false binding-associated region:1556-1576(MINT-8405441)|phosphorylated residue:1560-1560(MINT-8405439)|biotin tag:?-?(MINT-8405443) binding-associated region:201-393(MINT-8405433)|glutathione s tranferase tag:?-?(MINT-8405431)|mutation disrupting interaction:380-380(MINT-8405435) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P04050 uniprotkb:Q06697 intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7973137|mint:MINT-8405451|imex:IM-18582-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8405453(identity) refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8405461(identity) - crc64:A45C1360FF99F968 crc64:9580B53EEFB75345 figure legend:f3b f3a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 intact-crc:7C42D824881FA724|rigid:n7RYYoXvdKqBAvpo833pbhA8W1Y false biotin tag:?-?(MINT-8405454)|binding-associated region:1556-1576(MINT-8405456)|phosphorylated residue:1560-1560(MINT-8405458) mutation disrupting interaction:357-357(MINT-8405470)|glutathione s tranferase tag:?-?(MINT-8405466)|mutation disrupting interaction:380-380(MINT-8405462)|binding-associated region:201-393(MINT-8405464) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P04050 uniprotkb:Q06697 intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7973171|mint:MINT-8405473|imex:IM-18582-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8405485(identity) refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8405475(identity) - crc64:A45C1360FF99F968 crc64:9580B53EEFB75345 figure legend:f3b sf10b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 intact-crc:C658F2B194E28BD0|rigid:n7RYYoXvdKqBAvpo833pbhA8W1Y false binding-associated region:1556-1576(MINT-8405488)|phosphorylated residue:1557-1557(MINT-8405495)|phosphorylated residue:1560-1560(MINT-8405486)|biotin tag:?-?(MINT-8405490) mutation disrupting interaction:380-380(MINT-8405482)|binding-associated region:201-393(MINT-8405480)|glutathione s tranferase tag:?-?(MINT-8405478)|mutation disrupting interaction:357-357(MINT-8405476) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P04050 uniprotkb:Q06697 intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7973209|mint:MINT-8405498|imex:IM-18582-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8405500(identity) refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8405510(identity) - crc64:A45C1360FF99F968 crc64:9580B53EEFB75345 figure legend:f3b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 intact-crc:4B3EDCCE704484B4|rigid:n7RYYoXvdKqBAvpo833pbhA8W1Y false phosphorylated residue:1557-1557(MINT-8405501)|binding-associated region:1556-1576(MINT-8405505)|phosphorylated residue:1560-1560(MINT-8405507)|biotin tag:?-?(MINT-8405503) binding-associated region:201-393(MINT-8405513)|mutation disrupting interaction:380-380(MINT-8405511)|glutathione s tranferase tag:?-?(MINT-8405515) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P04050 uniprotkb:Q06697 intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7973243|mint:MINT-8405522|imex:IM-18582-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8405532(identity) refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8405524(identity) - crc64:A45C1360FF99F968 crc64:9580B53EEFB75345 figure legend:f3c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 intact-crc:F8A0D0DBB20122E5|rigid:n7RYYoXvdKqBAvpo833pbhA8W1Y false phosphorylated residue:1560-1560(MINT-8405533)|biotin tag:?-?(MINT-8405537)|binding-associated region:1556-1576(MINT-8405535)|phosphorylated residue:1557-1557(MINT-8405539) glutathione s tranferase tag:?-?(MINT-8405525)|binding-associated region:201-393(MINT-8405527)|mutation disrupting interaction:233-240(MINT-8405529) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P04050 uniprotkb:Q06697 intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7973277|mint:MINT-8405546|imex:IM-18582-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8405548(identity) refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8405558(identity) - crc64:A45C1360FF99F968 crc64:9580B53EEFB75345 figure legend:f3c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 intact-crc:C77F409DB085D339|rigid:n7RYYoXvdKqBAvpo833pbhA8W1Y false biotin tag:?-?(MINT-8405551)|binding-associated region:1556-1576(MINT-8405553)|phosphorylated residue:1557-1557(MINT-8405549)|phosphorylated residue:1560-1560(MINT-8405555) mutation disrupting interaction:254-261(MINT-8405559)|binding-associated region:201-393(MINT-8405561)|glutathione s tranferase tag:?-?(MINT-8405563) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q06697 uniprotkb:P04050 intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7973328|mint:MINT-8405568|imex:IM-18582-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8405570(identity) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8405578(identity) - crc64:9580B53EEFB75345 crc64:A45C1360FF99F968 figure legend:f3c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 intact-crc:E01559BEA4E08F12|rigid:n7RYYoXvdKqBAvpo833pbhA8W1Y false mutation decreasing interaction:304-309(MINT-8405575)|glutathione s tranferase tag:?-?(MINT-8405571)|binding-associated region:201-393(MINT-8405573) phosphorylated residue:1560-1560(MINT-8405579)|phosphorylated residue:1557-1557(MINT-8405585)|biotin tag:?-?(MINT-8405583)|binding-associated region:1556-1576(MINT-8405581) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q06697 uniprotkb:P04050 intact:EBI-29913|uniprotkb:D6VZ54|ensemblfungi:YLR418C intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C psi-mi:cdc73_yeast(display_long)|uniprotkb:RNA polymerase-associated protein CDC73(gene name synonym)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:YLR418C(locus name) psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym) psi-mi:"MI:0089"(protein array) Qiu et al. (2012) doi:10.1038/emboj.2012.188|pubmed:22796944|imex:IM-18582|mint:MINT-8404133 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7973362|mint:MINT-8405590|imex:IM-18582-38 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013522.1|sgd:S000004410|dip:DIP-1148N|mint:Q06697|ensemblfungi:YLR418C(gene)|ensemblfungi:YLR418C_mRNA(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016570"(histone modification)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0090262"(regulation of transcription-coupled nucleotide-excision repair)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2001165"(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues)|go:"GO:2001173"(regulation of histone H2B conserved C-terminal lysine ubiquitination)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR038103|rcsb pdb:3V46|rcsb pdb:4DM4|reactome:R-SCE-674695|reactome:R-SCE-75955|mint:MINT-8405602(identity) refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|mint:MINT-8405592(identity) - crc64:9580B53EEFB75345 crc64:A45C1360FF99F968 figure legend:f3c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/12/11 2014/10/16 rogid:9d/PessN2v7cZ2ZuQW1vjTnjcaQ559292 rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292 intact-crc:4957C8DFA26E45C0|rigid:n7RYYoXvdKqBAvpo833pbhA8W1Y false binding-associated region:201-393(MINT-8405605)|mutation decreasing interaction:315-323(MINT-8405603)|glutathione s tranferase tag:?-?(MINT-8405607) phosphorylated residue:1560-1560(MINT-8405599)|binding-associated region:1556-1576(MINT-8405597)|phosphorylated residue:1557-1557(MINT-8405593)|biotin tag:?-?(MINT-8405595) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0083"(peptide synthesis)