#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8BHN0	uniprotkb:Q9H3P7	intact:EBI-7970002|uniprotkb:Q9Z0T1|intact:UNK-5505543|uniprotkb:Q8C1D5|uniprotkb:Q810H0|uniprotkb:Q3UGL2|uniprotkb:Q8C021|ensembl:ENSMUSP00000029355	intact:EBI-1791792|uniprotkb:Q5VTJ0|uniprotkb:Q6P9F1|uniprotkb:Q8IZC5|uniprotkb:Q8N4D6|uniprotkb:Q9H6U3|uniprotkb:B2RB29|ensembl:ENSP00000355777	psi-mi:ppm1l_mouse(display_long)|uniprotkb:Protein phosphatase 1-like(gene name synonym)|uniprotkb:Protein phosphatase 2C isoform epsilon(gene name synonym)|uniprotkb:Ppm1l(gene name)|psi-mi:Ppm1l(display_short)|uniprotkb:Kiaa4175(gene name synonym)	psi-mi:gcp60_human(display_long)|uniprotkb:GOCAP1(gene name synonym)|uniprotkb:GOLPH1(gene name synonym)|uniprotkb:ACBD3(gene name)|psi-mi:ACBD3(display_short)|uniprotkb:GCP60(gene name synonym)|uniprotkb:Acyl-CoA-binding domain-containing protein 3(gene name synonym)|uniprotkb:Golgi phosphoprotein 1(gene name synonym)|uniprotkb:Golgi complex-associated protein 1(gene name synonym)|uniprotkb:PBR- and PKA-associated protein 7(gene name synonym)|uniprotkb:Peripheral benzodiazepine receptor-associated protein PAP7(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Shinoda et al. (2012)	mint:d-12-00708|pubmed:22796112|mint:MINT-8384350	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7970031|mint:MINT-8385163	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_848841.2|ensembl:ENSMUSG00000027784(gene)|ensembl:ENSMUST00000029355(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|reactome:R-MMU-1660661|mint:MINT-8385172(identity)|uniprotkb:Q8BHN0(original identifier)	refseq:NP_073572.2|dip:DIP-40673N|ensembl:ENSG00000182827(gene)|ensembl:ENST00000366812(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR009038(GOLD)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|interpro:IPR035984|interpro:IPR036598|mint:Q9H3P7|rcsb pdb:2N72|rcsb pdb:2N73|rcsb pdb:5LZ1|rcsb pdb:5LZ3|rcsb pdb:5LZ6|rcsb pdb:5TDQ|rcsb pdb:6HLN|rcsb pdb:6HLT|rcsb pdb:6HLV|rcsb pdb:6HLW|rcsb pdb:6HM8|rcsb pdb:6HMV|reactome:R-HSA-432722|mint:MINT-8385164(identity)|uniprotkb:Q9H3P7(original identifier)	-	comment:mint|comment:homomint|function:Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6	-	figure legend:F1A|comment:homomint|comment:domino|comment:mint	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2012/07/02	2014/10/16	rogid:A41hWoFn5MjUvq4tdwX84SpiBrE10090	rogid:jAaMXnoXG6RGj+lAgIYk1inXA6o9606	intact-crc:DFF9291F21798778|rigid:S+87w1KaEorwfXBA/Pzb38JnViw	false	fusion protein:?-?(MINT-8385175)	fusion protein:?-?(MINT-8385170)|binding-associated region:288-528(MINT-8385167)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8BHN0	uniprotkb:Q9H3P7	intact:EBI-7970002|uniprotkb:Q9Z0T1|intact:UNK-5505543|uniprotkb:Q8C1D5|uniprotkb:Q810H0|uniprotkb:Q3UGL2|uniprotkb:Q8C021|ensembl:ENSMUSP00000029355	intact:EBI-1791792|uniprotkb:Q5VTJ0|uniprotkb:Q6P9F1|uniprotkb:Q8IZC5|uniprotkb:Q8N4D6|uniprotkb:Q9H6U3|uniprotkb:B2RB29|ensembl:ENSP00000355777	psi-mi:ppm1l_mouse(display_long)|uniprotkb:Protein phosphatase 1-like(gene name synonym)|uniprotkb:Protein phosphatase 2C isoform epsilon(gene name synonym)|uniprotkb:Ppm1l(gene name)|psi-mi:Ppm1l(display_short)|uniprotkb:Kiaa4175(gene name synonym)	psi-mi:gcp60_human(display_long)|uniprotkb:GOCAP1(gene name synonym)|uniprotkb:GOLPH1(gene name synonym)|uniprotkb:ACBD3(gene name)|psi-mi:ACBD3(display_short)|uniprotkb:GCP60(gene name synonym)|uniprotkb:Acyl-CoA-binding domain-containing protein 3(gene name synonym)|uniprotkb:Golgi phosphoprotein 1(gene name synonym)|uniprotkb:Golgi complex-associated protein 1(gene name synonym)|uniprotkb:PBR- and PKA-associated protein 7(gene name synonym)|uniprotkb:Peripheral benzodiazepine receptor-associated protein PAP7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Shinoda et al. (2012)	mint:d-12-00708|pubmed:22796112|mint:MINT-8384350	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7970154|mint:MINT-8385179	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_848841.2|ensembl:ENSMUSG00000027784(gene)|ensembl:ENSMUST00000029355(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|reactome:R-MMU-1660661|mint:MINT-8385189(identity)|uniprotkb:Q8BHN0(original identifier)	refseq:NP_073572.2|dip:DIP-40673N|ensembl:ENSG00000182827(gene)|ensembl:ENST00000366812(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR009038(GOLD)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|interpro:IPR035984|interpro:IPR036598|mint:Q9H3P7|rcsb pdb:2N72|rcsb pdb:2N73|rcsb pdb:5LZ1|rcsb pdb:5LZ3|rcsb pdb:5LZ6|rcsb pdb:5TDQ|rcsb pdb:6HLN|rcsb pdb:6HLT|rcsb pdb:6HLV|rcsb pdb:6HLW|rcsb pdb:6HM8|rcsb pdb:6HMV|reactome:R-HSA-432722|mint:MINT-8385180(identity)|uniprotkb:Q9H3P7(original identifier)	-	comment:mint|comment:homomint|function:Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6	-	comment:homomint|comment:domino|comment:mint|figure legend:F1C F1E F4	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/07/02	2014/10/16	rogid:A41hWoFn5MjUvq4tdwX84SpiBrE10090	rogid:jAaMXnoXG6RGj+lAgIYk1inXA6o9606	intact-crc:7462C68EADCBB0F1|rigid:S+87w1KaEorwfXBA/Pzb38JnViw	false	flag tag:?-?(MINT-8385192)	glutathione s tranferase tag:?-?(MINT-8385186)|binding-associated region:407-528(MINT-8385183)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8BHN0	uniprotkb:Q92503	intact:EBI-7970002|uniprotkb:Q9Z0T1|intact:UNK-5505543|uniprotkb:Q8C1D5|uniprotkb:Q810H0|uniprotkb:Q3UGL2|uniprotkb:Q8C021|ensembl:ENSMUSP00000029355	intact:EBI-2855587|uniprotkb:Q99780|uniprotkb:B4DDI5|uniprotkb:D5G3K1|uniprotkb:A8K4E8|ensembl:ENSP00000390392|ensembl:ENSP00000408169|ensembl:ENSP00000466581	psi-mi:ppm1l_mouse(display_long)|uniprotkb:Protein phosphatase 1-like(gene name synonym)|uniprotkb:Protein phosphatase 2C isoform epsilon(gene name synonym)|uniprotkb:Ppm1l(gene name)|psi-mi:Ppm1l(display_short)|uniprotkb:Kiaa4175(gene name synonym)	psi-mi:s14l1_human(display_long)|uniprotkb:SEC14L1(gene name)|psi-mi:SEC14L1(display_short)|uniprotkb:SEC14L(gene name synonym)	psi-mi:"MI:0096"(pull down)	Shinoda et al. (2012)	mint:d-12-00708|pubmed:22796112|mint:MINT-8384350	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7970433|mint:MINT-8385223	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_848841.2|ensembl:ENSMUSG00000027784(gene)|ensembl:ENSMUST00000029355(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|reactome:R-MMU-1660661|mint:MINT-8385232(identity)|uniprotkb:Q8BHN0(original identifier)	refseq:NP_001034662.2|refseq:NP_001137473.1|refseq:NP_001191337.1|ensembl:ENSG00000129657|refseq:NP_001137470.1|refseq:NP_001191339.1|ensembl:ENSG00000129657(gene)|ensembl:ENST00000430767(transcript)|ensembl:ENST00000436233(transcript)|ensembl:ENST00000585618(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0015871"(choline transport)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0039552"(RIG-I binding)|go:"GO:0045087"(innate immune response)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR006797(MSF1)|interpro:IPR009038(GOLD)|interpro:IPR011074(Phosphatidylinositol transfer protein-like, N-terminal)|interpro:IPR036273|interpro:IPR036598|interpro:IPR036865|refseq:NP_001137471.1|refseq:NP_002994.3|mint:MINT-8385224(identity)|uniprotkb:Q92503(original identifier)	-	comment:mint|comment:homomint|function:Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6	-	figure legend:F4|comment:homomint|comment:domino|comment:mint	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/07/02	2014/10/16	rogid:A41hWoFn5MjUvq4tdwX84SpiBrE10090	rogid:DVQ2degWp4n5f9aY+9RrBCQ7AGg9606	intact-crc:EC1C8A19E29C4975|rigid:pzLqkLDfLW3PZs9VgVN2oDJi2UY	false	flag tag:?-?(MINT-8385235)	binding-associated region:523-674(MINT-8385227)|glutathione s tranferase tag:?-?(MINT-8385230)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8BHN0	uniprotkb:Q9BQS8	intact:EBI-7970002|uniprotkb:Q9Z0T1|intact:UNK-5505543|uniprotkb:Q8C1D5|uniprotkb:Q810H0|uniprotkb:Q3UGL2|uniprotkb:Q8C021|ensembl:ENSMUSP00000029355	intact:EBI-2869338|uniprotkb:Q96IV5|uniprotkb:Q3MJE6|uniprotkb:Q8TEF9|uniprotkb:Q86T41|uniprotkb:Q9H8P9|uniprotkb:Q86TB1|uniprotkb:B7ZKT7|ensembl:ENSP00000296137	psi-mi:ppm1l_mouse(display_long)|uniprotkb:Protein phosphatase 1-like(gene name synonym)|uniprotkb:Protein phosphatase 2C isoform epsilon(gene name synonym)|uniprotkb:Ppm1l(gene name)|psi-mi:Ppm1l(display_short)|uniprotkb:Kiaa4175(gene name synonym)	psi-mi:fyco1_human(display_long)|uniprotkb:FYCO1(gene name)|psi-mi:FYCO1(display_short)|uniprotkb:ZFYVE7(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Shinoda et al. (2012)	mint:d-12-00708|pubmed:22796112|mint:MINT-8384350	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7970389|mint:MINT-8385209	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_848841.2|ensembl:ENSMUSG00000027784(gene)|ensembl:ENSMUST00000029355(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|reactome:R-MMU-1660661|mint:MINT-8385218(identity)|uniprotkb:Q8BHN0(original identifier)	refseq:XP_011532413.1|refseq:XP_006713396.1|refseq:XP_006713397.1|refseq:NP_078789.2|ensembl:ENSG00000163820(gene)|ensembl:ENST00000296137(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016020"(membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR004012(RUN)|interpro:IPR009038(GOLD)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR036598|interpro:IPR037213|interpro:IPR042654|mint:Q9BQS8|rcsb pdb:5CX3|rcsb pdb:5D94|rcsb pdb:7BQI|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|dip:DIP-60600N|mint:MINT-8385210(identity)|uniprotkb:Q9BQS8(original identifier)	-	comment:mint|comment:homomint|function:Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6	-	figure legend:F4|comment:homomint|comment:domino|comment:mint	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/07/02	2014/10/16	rogid:A41hWoFn5MjUvq4tdwX84SpiBrE10090	rogid:/iOQiItN7ljXD08DN8DvQ1m6t0E9606	intact-crc:702300480269CF39|rigid:MOP0S+13j9H7b3KQS4XerQ68sl4	false	flag tag:?-?(MINT-8385221)	glutathione s tranferase tag:?-?(MINT-8385216)|binding-associated region:?-?(MINT-8385213)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8BHN0	uniprotkb:O76054	intact:EBI-7970002|uniprotkb:Q9Z0T1|intact:UNK-5505543|uniprotkb:Q8C1D5|uniprotkb:Q810H0|uniprotkb:Q3UGL2|uniprotkb:Q8C021|ensembl:ENSMUSP00000029355	intact:EBI-7970487|uniprotkb:Q53EQ2|uniprotkb:F5H3U4|uniprotkb:Q6PD61|intact:MINT-4871599|intact:MINT-3002196|uniprotkb:Q9ULN4|uniprotkb:B7Z8Q1|ensembl:ENSP00000478755	psi-mi:ppm1l_mouse(display_long)|uniprotkb:Protein phosphatase 1-like(gene name synonym)|uniprotkb:Protein phosphatase 2C isoform epsilon(gene name synonym)|uniprotkb:Ppm1l(gene name)|psi-mi:Ppm1l(display_short)|uniprotkb:Kiaa4175(gene name synonym)	psi-mi:s14l2_human(display_long)|uniprotkb:C22orf6(gene name synonym)|uniprotkb:SEC14L2(gene name)|psi-mi:SEC14L2(display_short)|uniprotkb:KIAA1186(gene name synonym)|uniprotkb:KIAA1658(gene name synonym)|uniprotkb:Alpha-tocopherol-associated protein(gene name synonym)|uniprotkb:Supernatant protein factor(gene name synonym)|uniprotkb:Squalene transfer protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Shinoda et al. (2012)	mint:d-12-00708|pubmed:22796112|mint:MINT-8384350	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7970528|mint:MINT-8385237	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_848841.2|ensembl:ENSMUSG00000027784(gene)|ensembl:ENSMUST00000029355(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|reactome:R-MMU-1660661|mint:MINT-8385246(identity)|uniprotkb:Q8BHN0(original identifier)	refseq:NP_203740.1|refseq:NP_001191133.1|refseq:NP_036561.1|go:"GO:0005829"(cytosol)|go:"GO:0008431"(vitamin E binding)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR009038(GOLD)|interpro:IPR011074(Phosphatidylinositol transfer protein-like, N-terminal)|interpro:IPR036273|interpro:IPR036598|interpro:IPR036865|rcsb pdb:1O6U|rcsb pdb:1OLM|rcsb pdb:4OMJ|rcsb pdb:4OMK|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000100003(gene)|ensembl:ENST00000615189(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|mint:MINT-8385238(identity)|uniprotkb:O76054(original identifier)	-	comment:mint|comment:homomint|function:Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6	comment:mint|function:Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell|comment:homomint	figure legend:F4|comment:homomint|comment:domino|comment:mint	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/07/02	2014/10/16	rogid:A41hWoFn5MjUvq4tdwX84SpiBrE10090	rogid:aHbEPWHfMpEGTvGqu6gcdNVrulk9606	intact-crc:905393B5AF87BEC7|rigid:Wr9WC7XB4BPyh9CQbuEnCH6j8JY	false	flag tag:?-?(MINT-8385249)	glutathione s tranferase tag:?-?(MINT-8385244)|binding-associated region:277-383(MINT-8385241)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8BHN0	uniprotkb:Q9H3P7	intact:EBI-7970002|uniprotkb:Q9Z0T1|intact:UNK-5505543|uniprotkb:Q8C1D5|uniprotkb:Q810H0|uniprotkb:Q3UGL2|uniprotkb:Q8C021|ensembl:ENSMUSP00000029355	intact:EBI-1791792|uniprotkb:Q5VTJ0|uniprotkb:Q6P9F1|uniprotkb:Q8IZC5|uniprotkb:Q8N4D6|uniprotkb:Q9H6U3|uniprotkb:B2RB29|ensembl:ENSP00000355777	psi-mi:ppm1l_mouse(display_long)|uniprotkb:Protein phosphatase 1-like(gene name synonym)|uniprotkb:Protein phosphatase 2C isoform epsilon(gene name synonym)|uniprotkb:Ppm1l(gene name)|psi-mi:Ppm1l(display_short)|uniprotkb:Kiaa4175(gene name synonym)	psi-mi:gcp60_human(display_long)|uniprotkb:GOCAP1(gene name synonym)|uniprotkb:GOLPH1(gene name synonym)|uniprotkb:ACBD3(gene name)|psi-mi:ACBD3(display_short)|uniprotkb:GCP60(gene name synonym)|uniprotkb:Acyl-CoA-binding domain-containing protein 3(gene name synonym)|uniprotkb:Golgi phosphoprotein 1(gene name synonym)|uniprotkb:Golgi complex-associated protein 1(gene name synonym)|uniprotkb:PBR- and PKA-associated protein 7(gene name synonym)|uniprotkb:Peripheral benzodiazepine receptor-associated protein PAP7(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Shinoda et al. (2012)	mint:d-12-00708|pubmed:22796112|mint:MINT-8384350	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7970349|mint:MINT-8385196	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_848841.2|ensembl:ENSMUSG00000027784(gene)|ensembl:ENSMUST00000029355(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|reactome:R-MMU-1660661|mint:MINT-8385202(identity)|uniprotkb:Q8BHN0(original identifier)	refseq:NP_073572.2|dip:DIP-40673N|ensembl:ENSG00000182827(gene)|ensembl:ENST00000366812(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR009038(GOLD)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|interpro:IPR035984|interpro:IPR036598|mint:Q9H3P7|rcsb pdb:2N72|rcsb pdb:2N73|rcsb pdb:5LZ1|rcsb pdb:5LZ3|rcsb pdb:5LZ6|rcsb pdb:5TDQ|rcsb pdb:6HLN|rcsb pdb:6HLT|rcsb pdb:6HLV|rcsb pdb:6HLW|rcsb pdb:6HM8|rcsb pdb:6HMV|reactome:R-HSA-432722|mint:MINT-8385197(identity)|uniprotkb:Q9H3P7(original identifier)	go:"GO:0097038"(perinuclear endoplasmic reticulum)	comment:mint|comment:homomint|function:Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6	-	figure legend:F2C|comment:homomint|comment:mint	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2012/07/02	2014/10/16	rogid:A41hWoFn5MjUvq4tdwX84SpiBrE10090	rogid:jAaMXnoXG6RGj+lAgIYk1inXA6o9606	intact-crc:408E45BFB8969A6E|rigid:S+87w1KaEorwfXBA/Pzb38JnViw	false	flag tag:?-?(MINT-8385205)	glutathione s tranferase tag:?-?(MINT-8385200)	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0707"(anti tag immunostaining)