#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P97710 uniprotkb:Q9R044 intact:EBI-7945080|uniprotkb:Q9QWI5|uniprotkb:O08951|intact:MINT-8019899|uniprotkb:O70426|ensembl:ENSRNOP00000006408 intact:EBI-7945021|uniprotkb:Q9QXX7|uniprotkb:Q9JIX2|intact:MINT-8384233 psi-mi:shps1_rat(display_long)|uniprotkb:Sirpa(gene name)|psi-mi:Sirpa(display_short)|uniprotkb:Bit(gene name synonym)|uniprotkb:Brain Ig-like molecule with tyrosine-based activation motifs(gene name synonym)|uniprotkb:CD172 antigen-like family member A(gene name synonym)|uniprotkb:Inhibitory receptor SHPS-1(gene name synonym)|uniprotkb:Mfr(gene name synonym)|uniprotkb:Macrophage fusion receptor(gene name synonym)|uniprotkb:Macrophage membrane protein MFP150(gene name synonym)|uniprotkb:Ptpns1(gene name synonym)|uniprotkb:Shps1(gene name synonym)|uniprotkb:Signal-regulatory protein alpha-1(gene name synonym)|uniprotkb:Sirp(gene name synonym) psi-mi:nphn_rat(display_long)|uniprotkb:Nphs1(gene name)|psi-mi:Nphs1(display_short)|uniprotkb:Nphn(gene name synonym)|uniprotkb:Renal glomerulus-specific cell adhesion receptor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kajiho et al. (2012) mint:fj-12-0184.r2|pubmed:22747997|mint:MINT-8384190 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7945015|mint:MINT-8384216 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_017446986.1|refseq:NP_037148.2|rgd:3449|ensembl:ENSRNOG00000004763(gene)|ensembl:ENSRNOT00000006408(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005886"(plasma membrane)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071349"(cellular response to interleukin-12)|go:"GO:0071641"(negative regulation of macrophage inflammatory protein 1 alpha production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0086080"(protein binding involved in heterotypic cell-cell adhesion)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0097530"(granulocyte migration)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1903720"(negative regulation of I-kappaB phosphorylation)|go:"GO:1990405"(protein antigen binding)|reactome:R-RNO-2172127|reactome:R-RNO-391160|reactome:R-RNO-6798695|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-RNO-202733|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032651"(regulation of interleukin-1 beta production)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0035696"(monocyte extravasation)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|mint:MINT-8384218(identity) interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:NP_072150.1|rgd:620460|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003094"(glomerular filtration)|go:"GO:0005604"(basement membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007254"(JNK cascade)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036057"(slit diaphragm)|go:"GO:0042995"(cell projection)|go:"GO:0044062"(regulation of excretion)|go:"GO:0045121"(membrane raft)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0030507"(spectrin binding)|interpro:IPR036116|interpro:IPR036179|reactome:R-RNO-373753|mint:MINT-8384280(identity) - comment:mint|comment:homomint comment:mint|comment:homomint comment:homomint|comment:mint|figure legend:f3a f3b f3c taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/06/26 2014/10/16 rogid:LTJvythPYcoIeWQ0NLHRK8SaJVE10116 rogid:O6dRRlNXsrORhIiGJek5KOR5aEs10116 intact-crc:1C10DA2140B16BFB|rigid:VYINTIMCSyoIA+qHMFMrAbvakUw false flag tag:?-?(MINT-8384286) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P97710 uniprotkb:Q9R044 intact:EBI-7945080|uniprotkb:Q9QWI5|uniprotkb:O08951|intact:MINT-8019899|uniprotkb:O70426|ensembl:ENSRNOP00000006408 intact:EBI-7945021|uniprotkb:Q9QXX7|uniprotkb:Q9JIX2|intact:MINT-8384233 psi-mi:shps1_rat(display_long)|uniprotkb:Sirpa(gene name)|psi-mi:Sirpa(display_short)|uniprotkb:Bit(gene name synonym)|uniprotkb:Brain Ig-like molecule with tyrosine-based activation motifs(gene name synonym)|uniprotkb:CD172 antigen-like family member A(gene name synonym)|uniprotkb:Inhibitory receptor SHPS-1(gene name synonym)|uniprotkb:Mfr(gene name synonym)|uniprotkb:Macrophage fusion receptor(gene name synonym)|uniprotkb:Macrophage membrane protein MFP150(gene name synonym)|uniprotkb:Ptpns1(gene name synonym)|uniprotkb:Shps1(gene name synonym)|uniprotkb:Signal-regulatory protein alpha-1(gene name synonym)|uniprotkb:Sirp(gene name synonym) psi-mi:nphn_rat(display_long)|uniprotkb:Nphs1(gene name)|psi-mi:Nphs1(display_short)|uniprotkb:Nphn(gene name synonym)|uniprotkb:Renal glomerulus-specific cell adhesion receptor(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kajiho et al. (2012) mint:fj-12-0184.r2|pubmed:22747997|mint:MINT-8384190 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7945216|mint:MINT-8384298 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_017446986.1|refseq:NP_037148.2|rgd:3449|ensembl:ENSRNOG00000004763(gene)|ensembl:ENSRNOT00000006408(transcript)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005886"(plasma membrane)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071349"(cellular response to interleukin-12)|go:"GO:0071641"(negative regulation of macrophage inflammatory protein 1 alpha production)|go:"GO:0071650"("negative regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0086080"(protein binding involved in heterotypic cell-cell adhesion)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0097530"(granulocyte migration)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1903720"(negative regulation of I-kappaB phosphorylation)|go:"GO:1990405"(protein antigen binding)|reactome:R-RNO-2172127|reactome:R-RNO-391160|reactome:R-RNO-6798695|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-RNO-202733|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032651"(regulation of interleukin-1 beta production)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0035696"(monocyte extravasation)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|mint:MINT-8384301(identity) interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:NP_072150.1|rgd:620460|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003094"(glomerular filtration)|go:"GO:0005604"(basement membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007254"(JNK cascade)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036057"(slit diaphragm)|go:"GO:0042995"(cell projection)|go:"GO:0044062"(regulation of excretion)|go:"GO:0045121"(membrane raft)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0030507"(spectrin binding)|interpro:IPR036116|interpro:IPR036179|reactome:R-RNO-373753|mint:MINT-8384300(identity) - comment:mint|comment:homomint comment:mint|comment:homomint figure legend:f3d|comment:homomint|comment:mint taxid:10116(rat-kidney)|taxid:10116(Rat kidney) - 2012/06/26 2014/10/16 rogid:LTJvythPYcoIeWQ0NLHRK8SaJVE10116 rogid:O6dRRlNXsrORhIiGJek5KOR5aEs10116 intact-crc:B48854FF28BAA07F|rigid:VYINTIMCSyoIA+qHMFMrAbvakUw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)