#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P02563 uniprotkb:P02563 intact:EBI-6122328|uniprotkb:Q63351 intact:EBI-6122328|uniprotkb:Q63351 psi-mi:myh6_rat(display_long)|uniprotkb:Myh6(gene name)|psi-mi:Myh6(display_short)|uniprotkb:Myosin heavy chain 6(gene name synonym)|uniprotkb:Myosin heavy chain, cardiac muscle alpha isoform(gene name synonym) psi-mi:myh6_rat(display_long)|uniprotkb:Myh6(gene name)|psi-mi:Myh6(display_short)|uniprotkb:Myosin heavy chain 6(gene name synonym)|uniprotkb:Myosin heavy chain, cardiac muscle alpha isoform(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Thompson et al. (2012) pubmed:22728135|mint:MINT-8382275 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7938479|mint:MINT-8382280 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:62029|dip:DIP-41048N|reactome:R-RNO-390522|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007512"(adult heart development)|go:"GO:0007522"(visceral muscle development)|go:"GO:0007568"(aging)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009408"(response to heat)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016459"(myosin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0032982"(myosin filament)|go:"GO:0042802"(identical protein binding)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0055009"(atrial cardiac muscle tissue morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060420"(regulation of heart growth)|go:"GO:1905243"(cellular response to 3,3',5-triiodo-L-thyronine)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:MINT-8382282(identity) rgd:62029|dip:DIP-41048N|reactome:R-RNO-390522|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007512"(adult heart development)|go:"GO:0007522"(visceral muscle development)|go:"GO:0007568"(aging)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009408"(response to heat)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016459"(myosin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0032982"(myosin filament)|go:"GO:0042802"(identical protein binding)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0055009"(atrial cardiac muscle tissue morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060420"(regulation of heart growth)|go:"GO:1905243"(cellular response to 3,3',5-triiodo-L-thyronine)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:MINT-8382283(identity) - - - figure legend:f1|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/06 2014/10/16 rogid:nqeGE5gpHiH/OIrWFbbj4AF/AKM10116 rogid:nqeGE5gpHiH/OIrWFbbj4AF/AKM10116 intact-crc:9890794527E8C29E|rigid:Z93nSSzCASC48Fb/YfEmjTQON+E false binding-associated region:1231-1938(MINT-8382305)|tandem tag:?-?(MINT-8382302) tandem tag:?-?(MINT-8382308)|binding-associated region:1231-1938(MINT-8382311) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02563 uniprotkb:P02563 intact:EBI-6122328|uniprotkb:Q63351 intact:EBI-6122328|uniprotkb:Q63351 psi-mi:myh6_rat(display_long)|uniprotkb:Myh6(gene name)|psi-mi:Myh6(display_short)|uniprotkb:Myosin heavy chain 6(gene name synonym)|uniprotkb:Myosin heavy chain, cardiac muscle alpha isoform(gene name synonym) psi-mi:myh6_rat(display_long)|uniprotkb:Myh6(gene name)|psi-mi:Myh6(display_short)|uniprotkb:Myosin heavy chain 6(gene name synonym)|uniprotkb:Myosin heavy chain, cardiac muscle alpha isoform(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Thompson et al. (2012) pubmed:22728135|mint:MINT-8382275 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7938503|mint:MINT-8382286 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:62029|dip:DIP-41048N|reactome:R-RNO-390522|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007512"(adult heart development)|go:"GO:0007522"(visceral muscle development)|go:"GO:0007568"(aging)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009408"(response to heat)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016459"(myosin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0032982"(myosin filament)|go:"GO:0042802"(identical protein binding)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0055009"(atrial cardiac muscle tissue morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060420"(regulation of heart growth)|go:"GO:1905243"(cellular response to 3,3',5-triiodo-L-thyronine)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:MINT-8382288(identity) rgd:62029|dip:DIP-41048N|reactome:R-RNO-390522|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007512"(adult heart development)|go:"GO:0007522"(visceral muscle development)|go:"GO:0007568"(aging)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009408"(response to heat)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016459"(myosin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0032982"(myosin filament)|go:"GO:0042802"(identical protein binding)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0055009"(atrial cardiac muscle tissue morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060420"(regulation of heart growth)|go:"GO:1905243"(cellular response to 3,3',5-triiodo-L-thyronine)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:MINT-8382289(identity) - - - figure legend:f2B|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/06 2014/10/16 rogid:nqeGE5gpHiH/OIrWFbbj4AF/AKM10116 rogid:nqeGE5gpHiH/OIrWFbbj4AF/AKM10116 intact-crc:893135DE9DE36EAF|rigid:Z93nSSzCASC48Fb/YfEmjTQON+E false binding-associated region:1231-1938(MINT-8382336)|tandem tag:?-?(MINT-8382334) binding-associated region:1231-1938(MINT-8382354)|mutation disrupting interaction:1922-1922(MINT-8382358)|mutation disrupting interaction:1920-1920(MINT-8382356)|mutation disrupting interaction:1924-1924(MINT-8382360)|tandem tag:?-?(MINT-8382351)|mutation disrupting interaction:1926-1926(MINT-8382362) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02563 uniprotkb:P02563 intact:EBI-6122328|uniprotkb:Q63351 intact:EBI-6122328|uniprotkb:Q63351 psi-mi:myh6_rat(display_long)|uniprotkb:Myh6(gene name)|psi-mi:Myh6(display_short)|uniprotkb:Myosin heavy chain 6(gene name synonym)|uniprotkb:Myosin heavy chain, cardiac muscle alpha isoform(gene name synonym) psi-mi:myh6_rat(display_long)|uniprotkb:Myh6(gene name)|psi-mi:Myh6(display_short)|uniprotkb:Myosin heavy chain 6(gene name synonym)|uniprotkb:Myosin heavy chain, cardiac muscle alpha isoform(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Thompson et al. (2012) pubmed:22728135|mint:MINT-8382275 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7938560|mint:MINT-8382406 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:62029|dip:DIP-41048N|reactome:R-RNO-390522|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007512"(adult heart development)|go:"GO:0007522"(visceral muscle development)|go:"GO:0007568"(aging)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009408"(response to heat)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016459"(myosin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0032982"(myosin filament)|go:"GO:0042802"(identical protein binding)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0055009"(atrial cardiac muscle tissue morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060420"(regulation of heart growth)|go:"GO:1905243"(cellular response to 3,3',5-triiodo-L-thyronine)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:MINT-8382414(identity) rgd:62029|dip:DIP-41048N|reactome:R-RNO-390522|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007512"(adult heart development)|go:"GO:0007522"(visceral muscle development)|go:"GO:0007568"(aging)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009408"(response to heat)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016459"(myosin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0032982"(myosin filament)|go:"GO:0042802"(identical protein binding)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0055009"(atrial cardiac muscle tissue morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060420"(regulation of heart growth)|go:"GO:1905243"(cellular response to 3,3',5-triiodo-L-thyronine)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:MINT-8382408(identity) - - - comment:homomint|comment:mint|figure legend:f2A taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/06 2014/10/16 rogid:nqeGE5gpHiH/OIrWFbbj4AF/AKM10116 rogid:nqeGE5gpHiH/OIrWFbbj4AF/AKM10116 intact-crc:A06BC55E83079638|rigid:Z93nSSzCASC48Fb/YfEmjTQON+E false mutation disrupting interaction:1919-1938(MINT-8382618)|tandem tag:?-?(MINT-8382417)|binding-associated region:1919-1938(MINT-8382415) tandem tag:?-?(MINT-8382411)|binding-associated region:1231-1938(MINT-8382409) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02563 uniprotkb:P02563 intact:EBI-6122328|uniprotkb:Q63351 intact:EBI-6122328|uniprotkb:Q63351 psi-mi:myh6_rat(display_long)|uniprotkb:Myh6(gene name)|psi-mi:Myh6(display_short)|uniprotkb:Myosin heavy chain 6(gene name synonym)|uniprotkb:Myosin heavy chain, cardiac muscle alpha isoform(gene name synonym) psi-mi:myh6_rat(display_long)|uniprotkb:Myh6(gene name)|psi-mi:Myh6(display_short)|uniprotkb:Myosin heavy chain 6(gene name synonym)|uniprotkb:Myosin heavy chain, cardiac muscle alpha isoform(gene name synonym) psi-mi:"MI:0067"(light scattering) Thompson et al. (2012) pubmed:22728135|mint:MINT-8382275 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7938651|mint:MINT-8382508 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:62029|dip:DIP-41048N|reactome:R-RNO-390522|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007512"(adult heart development)|go:"GO:0007522"(visceral muscle development)|go:"GO:0007568"(aging)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009408"(response to heat)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016459"(myosin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0032982"(myosin filament)|go:"GO:0042802"(identical protein binding)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0055009"(atrial cardiac muscle tissue morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060420"(regulation of heart growth)|go:"GO:1905243"(cellular response to 3,3',5-triiodo-L-thyronine)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:MINT-8382510(identity) rgd:62029|dip:DIP-41048N|reactome:R-RNO-390522|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007512"(adult heart development)|go:"GO:0007522"(visceral muscle development)|go:"GO:0007568"(aging)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009408"(response to heat)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016459"(myosin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0032982"(myosin filament)|go:"GO:0042802"(identical protein binding)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0055009"(atrial cardiac muscle tissue morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060420"(regulation of heart growth)|go:"GO:1905243"(cellular response to 3,3',5-triiodo-L-thyronine)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:MINT-8382524(identity) - - - comment:homomint|comment:mint|figure legend:f3B taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/06 2014/10/16 rogid:nqeGE5gpHiH/OIrWFbbj4AF/AKM10116 rogid:nqeGE5gpHiH/OIrWFbbj4AF/AKM10116 intact-crc:C82F4B14E023A4A4|rigid:Z93nSSzCASC48Fb/YfEmjTQON+E false binding-associated region:1231-1938(MINT-8382513)|mutation disrupting interaction:1922-1922(MINT-8382517)|mutation disrupting interaction:1926-1926(MINT-8382521)|mutation disrupting interaction:1924-1924(MINT-8382519)|tandem tag:?-?(MINT-8382511)|mutation disrupting interaction:1920-1920(MINT-8382515) binding-associated region:1231-1938(MINT-8382527)|tandem tag:?-?(MINT-8382525) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02563 uniprotkb:P02563 intact:EBI-6122328|uniprotkb:Q63351 intact:EBI-6122328|uniprotkb:Q63351 psi-mi:myh6_rat(display_long)|uniprotkb:Myh6(gene name)|psi-mi:Myh6(display_short)|uniprotkb:Myosin heavy chain 6(gene name synonym)|uniprotkb:Myosin heavy chain, cardiac muscle alpha isoform(gene name synonym) psi-mi:myh6_rat(display_long)|uniprotkb:Myh6(gene name)|psi-mi:Myh6(display_short)|uniprotkb:Myosin heavy chain 6(gene name synonym)|uniprotkb:Myosin heavy chain, cardiac muscle alpha isoform(gene name synonym) psi-mi:"MI:0067"(light scattering) Thompson et al. (2012) pubmed:22728135|mint:MINT-8382275 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7938595|mint:MINT-8382365 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:62029|dip:DIP-41048N|reactome:R-RNO-390522|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007512"(adult heart development)|go:"GO:0007522"(visceral muscle development)|go:"GO:0007568"(aging)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009408"(response to heat)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016459"(myosin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0032982"(myosin filament)|go:"GO:0042802"(identical protein binding)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0055009"(atrial cardiac muscle tissue morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060420"(regulation of heart growth)|go:"GO:1905243"(cellular response to 3,3',5-triiodo-L-thyronine)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:MINT-8382367(identity) rgd:62029|dip:DIP-41048N|reactome:R-RNO-390522|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007512"(adult heart development)|go:"GO:0007522"(visceral muscle development)|go:"GO:0007568"(aging)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009408"(response to heat)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016459"(myosin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0032982"(myosin filament)|go:"GO:0042802"(identical protein binding)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0055009"(atrial cardiac muscle tissue morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060420"(regulation of heart growth)|go:"GO:1905243"(cellular response to 3,3',5-triiodo-L-thyronine)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:MINT-8382381(identity) - - - comment:homomint|comment:mint|figure legend:f3B taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/06 2014/10/16 rogid:nqeGE5gpHiH/OIrWFbbj4AF/AKM10116 rogid:nqeGE5gpHiH/OIrWFbbj4AF/AKM10116 intact-crc:9980DF4EADF2A7FD|rigid:Z93nSSzCASC48Fb/YfEmjTQON+E false mutation disrupting interaction:1920-1920(MINT-8382374)|tandem tag:?-?(MINT-8382378)|mutation disrupting interaction:1922-1922(MINT-8382372)|mutation disrupting interaction:1926-1926(MINT-8382368)|binding-associated region:1231-1938(MINT-8382376)|mutation disrupting interaction:1924-1924(MINT-8382370) mutation disrupting interaction:1920-1920(MINT-8382388)|mutation disrupting interaction:1922-1922(MINT-8382386)|tandem tag:?-?(MINT-8382392)|binding-associated region:1231-1938(MINT-8382390)|mutation disrupting interaction:1924-1924(MINT-8382384)|mutation disrupting interaction:1926-1926(MINT-8382382) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P02563 uniprotkb:P02563 intact:EBI-6122328|uniprotkb:Q63351 intact:EBI-6122328|uniprotkb:Q63351 psi-mi:myh6_rat(display_long)|uniprotkb:Myh6(gene name)|psi-mi:Myh6(display_short)|uniprotkb:Myosin heavy chain 6(gene name synonym)|uniprotkb:Myosin heavy chain, cardiac muscle alpha isoform(gene name synonym) psi-mi:myh6_rat(display_long)|uniprotkb:Myh6(gene name)|psi-mi:Myh6(display_short)|uniprotkb:Myosin heavy chain 6(gene name synonym)|uniprotkb:Myosin heavy chain, cardiac muscle alpha isoform(gene name synonym) psi-mi:"MI:0067"(light scattering) Thompson et al. (2012) pubmed:22728135|mint:MINT-8382275 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7938691|mint:MINT-8382545 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:62029|dip:DIP-41048N|reactome:R-RNO-390522|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007512"(adult heart development)|go:"GO:0007522"(visceral muscle development)|go:"GO:0007568"(aging)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009408"(response to heat)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016459"(myosin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0032982"(myosin filament)|go:"GO:0042802"(identical protein binding)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0055009"(atrial cardiac muscle tissue morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060420"(regulation of heart growth)|go:"GO:1905243"(cellular response to 3,3',5-triiodo-L-thyronine)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:MINT-8382561(identity) rgd:62029|dip:DIP-41048N|reactome:R-RNO-390522|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007512"(adult heart development)|go:"GO:0007522"(visceral muscle development)|go:"GO:0007568"(aging)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009408"(response to heat)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016459"(myosin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0032982"(myosin filament)|go:"GO:0042802"(identical protein binding)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0055009"(atrial cardiac muscle tissue morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060420"(regulation of heart growth)|go:"GO:1905243"(cellular response to 3,3',5-triiodo-L-thyronine)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:MINT-8382547(identity) - - - comment:homomint|comment:mint|figure legend:f3A taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/06 2014/10/16 rogid:nqeGE5gpHiH/OIrWFbbj4AF/AKM10116 rogid:nqeGE5gpHiH/OIrWFbbj4AF/AKM10116 intact-crc:75E51BE925A3C38B|rigid:Z93nSSzCASC48Fb/YfEmjTQON+E false tandem tag:?-?(MINT-8382562)|binding-associated region:1231-1938(MINT-8382564) tandem tag:?-?(MINT-8382548)|binding-associated region:1231-1938(MINT-8382550) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)