#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O54788 uniprotkb:O54786 intact:EBI-7365197|intact:MINT-142143|ensembl:ENSMUSP00000030893 intact:EBI-1634519|uniprotkb:O54787|uniprotkb:Q8BQC7|uniprotkb:B2KFX0|ensembl:ENSMUSP00000030816 psi-mi:dffb_mouse(display_long)|uniprotkb:Dffb(gene name)|psi-mi:Dffb(display_short)|uniprotkb:Cad(gene name synonym)|uniprotkb:DNA fragmentation factor 40 kDa subunit(gene name synonym)|uniprotkb:Caspase-activated deoxyribonuclease(gene name synonym) psi-mi:dffa_mouse(display_long)|uniprotkb:Dffa(gene name)|psi-mi:Dffa(display_short)|uniprotkb:Icad(gene name synonym)|uniprotkb:DNA fragmentation factor 45 kDa subunit(gene name synonym)|uniprotkb:Inhibitor of CAD(gene name synonym) psi-mi:"MI:0081"(peptide array) Kutscher et al. (2012) pubmed:22727028|mint:MINT-8383086|mint:fj-12-0127.r1|doi:10.1111/j.1742-4658.2012.08673 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7936960|mint:MINT-8383103 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031885.3|ensembl:ENSMUSG00000029027(gene)|ensembl:ENSMUST00000030893(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006308"(DNA catabolic process)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015311(Apoptosis, DNA fragmentation factor 40 kDa)|interpro:IPR039729|mint:O54788|rcsb pdb:1C9F|rcsb pdb:1F2R|rcsb pdb:1V0D|reactome:R-MMU-140342|mint:MINT-8383105(identity) refseq:NP_001020467.1|ensembl:ENSMUSG00000028974(gene)|ensembl:ENSMUST00000030816(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032076"(negative regulation of deoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0060703"(deoxyribonuclease inhibitor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015121(DNA Fragmentation factor 45kDa, C terminal)|interpro:IPR017299(DNA fragmentation factor, alpha subunit)|interpro:IPR027296|rcsb pdb:1F2R|reactome:R-MMU-140342|mint:MINT-8383106(identity) - comment:mint|function:Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology|comment:homomint - comment:homomint|comment:mint|figure legend:t1 f1a taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/19 2014/10/16 rogid:6BiQzdEqkkJvzK4tj/xdBvpkWKY10090 rogid:MVg3+6pxmmcKBjFz1apoG3Di0Ig10090 intact-crc:0C5B1F3D4BE4E756|rigid:88YVovLIn19pXwYxS3t6DpLSqHw false - binding-associated region:43-74(MINT-8383109) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:O54788 uniprotkb:O54786 intact:EBI-7365197|intact:MINT-142143|ensembl:ENSMUSP00000030893 intact:EBI-1634519|uniprotkb:O54787|uniprotkb:Q8BQC7|uniprotkb:B2KFX0|ensembl:ENSMUSP00000030816 psi-mi:dffb_mouse(display_long)|uniprotkb:Dffb(gene name)|psi-mi:Dffb(display_short)|uniprotkb:Cad(gene name synonym)|uniprotkb:DNA fragmentation factor 40 kDa subunit(gene name synonym)|uniprotkb:Caspase-activated deoxyribonuclease(gene name synonym) psi-mi:dffa_mouse(display_long)|uniprotkb:Dffa(gene name)|psi-mi:Dffa(display_short)|uniprotkb:Icad(gene name synonym)|uniprotkb:DNA fragmentation factor 45 kDa subunit(gene name synonym)|uniprotkb:Inhibitor of CAD(gene name synonym) psi-mi:"MI:0081"(peptide array) Kutscher et al. (2012) pubmed:22727028|mint:MINT-8383086|mint:fj-12-0127.r1|doi:10.1111/j.1742-4658.2012.08673 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7936975|mint:MINT-8383116 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031885.3|ensembl:ENSMUSG00000029027(gene)|ensembl:ENSMUST00000030893(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006308"(DNA catabolic process)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015311(Apoptosis, DNA fragmentation factor 40 kDa)|interpro:IPR039729|mint:O54788|rcsb pdb:1C9F|rcsb pdb:1F2R|rcsb pdb:1V0D|reactome:R-MMU-140342|mint:MINT-8383118(identity) refseq:NP_001020467.1|ensembl:ENSMUSG00000028974(gene)|ensembl:ENSMUST00000030816(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032076"(negative regulation of deoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0060703"(deoxyribonuclease inhibitor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015121(DNA Fragmentation factor 45kDa, C terminal)|interpro:IPR017299(DNA fragmentation factor, alpha subunit)|interpro:IPR027296|rcsb pdb:1F2R|reactome:R-MMU-140342|mint:MINT-8383120(identity) - comment:mint|function:Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology|comment:homomint - comment:homomint|comment:mint|figure legend:t1 f1a taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/19 2014/10/16 rogid:6BiQzdEqkkJvzK4tj/xdBvpkWKY10090 rogid:MVg3+6pxmmcKBjFz1apoG3Di0Ig10090 intact-crc:F48AB4CE6CAD9F1B|rigid:88YVovLIn19pXwYxS3t6DpLSqHw false - binding-associated region:97-122(MINT-8383121) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:O54788 uniprotkb:O54786 intact:EBI-7365197|intact:MINT-142143|ensembl:ENSMUSP00000030893 intact:EBI-1634519|uniprotkb:O54787|uniprotkb:Q8BQC7|uniprotkb:B2KFX0|ensembl:ENSMUSP00000030816 psi-mi:dffb_mouse(display_long)|uniprotkb:Dffb(gene name)|psi-mi:Dffb(display_short)|uniprotkb:Cad(gene name synonym)|uniprotkb:DNA fragmentation factor 40 kDa subunit(gene name synonym)|uniprotkb:Caspase-activated deoxyribonuclease(gene name synonym) psi-mi:dffa_mouse(display_long)|uniprotkb:Dffa(gene name)|psi-mi:Dffa(display_short)|uniprotkb:Icad(gene name synonym)|uniprotkb:DNA fragmentation factor 45 kDa subunit(gene name synonym)|uniprotkb:Inhibitor of CAD(gene name synonym) psi-mi:"MI:0081"(peptide array) Kutscher et al. (2012) pubmed:22727028|mint:MINT-8383086|mint:fj-12-0127.r1|doi:10.1111/j.1742-4658.2012.08673 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7936990|mint:MINT-8383126 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031885.3|ensembl:ENSMUSG00000029027(gene)|ensembl:ENSMUST00000030893(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006308"(DNA catabolic process)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015311(Apoptosis, DNA fragmentation factor 40 kDa)|interpro:IPR039729|mint:O54788|rcsb pdb:1C9F|rcsb pdb:1F2R|rcsb pdb:1V0D|reactome:R-MMU-140342|mint:MINT-8383128(identity) refseq:NP_001020467.1|ensembl:ENSMUSG00000028974(gene)|ensembl:ENSMUST00000030816(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032076"(negative regulation of deoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0060703"(deoxyribonuclease inhibitor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015121(DNA Fragmentation factor 45kDa, C terminal)|interpro:IPR017299(DNA fragmentation factor, alpha subunit)|interpro:IPR027296|rcsb pdb:1F2R|reactome:R-MMU-140342|mint:MINT-8383130(identity) - comment:mint|function:Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology|comment:homomint - comment:homomint|comment:mint|figure legend:t1 f1a taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/19 2014/10/16 rogid:6BiQzdEqkkJvzK4tj/xdBvpkWKY10090 rogid:MVg3+6pxmmcKBjFz1apoG3Di0Ig10090 intact-crc:42F095588D00E515|rigid:88YVovLIn19pXwYxS3t6DpLSqHw false - binding-associated region:127-152(MINT-8383131) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:O54788 uniprotkb:O54786 intact:EBI-7365197|intact:MINT-142143|ensembl:ENSMUSP00000030893 intact:EBI-1634519|uniprotkb:O54787|uniprotkb:Q8BQC7|uniprotkb:B2KFX0|ensembl:ENSMUSP00000030816 psi-mi:dffb_mouse(display_long)|uniprotkb:Dffb(gene name)|psi-mi:Dffb(display_short)|uniprotkb:Cad(gene name synonym)|uniprotkb:DNA fragmentation factor 40 kDa subunit(gene name synonym)|uniprotkb:Caspase-activated deoxyribonuclease(gene name synonym) psi-mi:dffa_mouse(display_long)|uniprotkb:Dffa(gene name)|psi-mi:Dffa(display_short)|uniprotkb:Icad(gene name synonym)|uniprotkb:DNA fragmentation factor 45 kDa subunit(gene name synonym)|uniprotkb:Inhibitor of CAD(gene name synonym) psi-mi:"MI:0081"(peptide array) Kutscher et al. (2012) pubmed:22727028|mint:MINT-8383086|mint:fj-12-0127.r1|doi:10.1111/j.1742-4658.2012.08673 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7937005|mint:MINT-8383136 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031885.3|ensembl:ENSMUSG00000029027(gene)|ensembl:ENSMUST00000030893(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006308"(DNA catabolic process)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015311(Apoptosis, DNA fragmentation factor 40 kDa)|interpro:IPR039729|mint:O54788|rcsb pdb:1C9F|rcsb pdb:1F2R|rcsb pdb:1V0D|reactome:R-MMU-140342|mint:MINT-8383138(identity) refseq:NP_001020467.1|ensembl:ENSMUSG00000028974(gene)|ensembl:ENSMUST00000030816(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032076"(negative regulation of deoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0060703"(deoxyribonuclease inhibitor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015121(DNA Fragmentation factor 45kDa, C terminal)|interpro:IPR017299(DNA fragmentation factor, alpha subunit)|interpro:IPR027296|rcsb pdb:1F2R|reactome:R-MMU-140342|mint:MINT-8383140(identity) - comment:mint|function:Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology|comment:homomint - comment:homomint|comment:mint|figure legend:t1 f1a taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/19 2014/10/16 rogid:6BiQzdEqkkJvzK4tj/xdBvpkWKY10090 rogid:MVg3+6pxmmcKBjFz1apoG3Di0Ig10090 intact-crc:6A4248600F769688|rigid:88YVovLIn19pXwYxS3t6DpLSqHw false - binding-associated region:169-206(MINT-8383141) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:O54788 uniprotkb:O54786 intact:EBI-7365197|intact:MINT-142143|ensembl:ENSMUSP00000030893 intact:EBI-1634519|uniprotkb:O54787|uniprotkb:Q8BQC7|uniprotkb:B2KFX0|ensembl:ENSMUSP00000030816 psi-mi:dffb_mouse(display_long)|uniprotkb:Dffb(gene name)|psi-mi:Dffb(display_short)|uniprotkb:Cad(gene name synonym)|uniprotkb:DNA fragmentation factor 40 kDa subunit(gene name synonym)|uniprotkb:Caspase-activated deoxyribonuclease(gene name synonym) psi-mi:dffa_mouse(display_long)|uniprotkb:Dffa(gene name)|psi-mi:Dffa(display_short)|uniprotkb:Icad(gene name synonym)|uniprotkb:DNA fragmentation factor 45 kDa subunit(gene name synonym)|uniprotkb:Inhibitor of CAD(gene name synonym) psi-mi:"MI:0081"(peptide array) Kutscher et al. (2012) pubmed:22727028|mint:MINT-8383086|mint:fj-12-0127.r1|doi:10.1111/j.1742-4658.2012.08673 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7937020|mint:MINT-8383146 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031885.3|ensembl:ENSMUSG00000029027(gene)|ensembl:ENSMUST00000030893(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006308"(DNA catabolic process)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015311(Apoptosis, DNA fragmentation factor 40 kDa)|interpro:IPR039729|mint:O54788|rcsb pdb:1C9F|rcsb pdb:1F2R|rcsb pdb:1V0D|reactome:R-MMU-140342|mint:MINT-8383148(identity) refseq:NP_001020467.1|ensembl:ENSMUSG00000028974(gene)|ensembl:ENSMUST00000030816(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032076"(negative regulation of deoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0060703"(deoxyribonuclease inhibitor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015121(DNA Fragmentation factor 45kDa, C terminal)|interpro:IPR017299(DNA fragmentation factor, alpha subunit)|interpro:IPR027296|rcsb pdb:1F2R|reactome:R-MMU-140342|mint:MINT-8383150(identity) - comment:mint|function:Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology|comment:homomint - comment:homomint|comment:mint|figure legend:t1 f1a taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/19 2014/10/16 rogid:6BiQzdEqkkJvzK4tj/xdBvpkWKY10090 rogid:MVg3+6pxmmcKBjFz1apoG3Di0Ig10090 intact-crc:18D8CB98824B6F62|rigid:88YVovLIn19pXwYxS3t6DpLSqHw false - binding-associated region:205-236(MINT-8383151) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:O54788 uniprotkb:O00273 intact:EBI-7365197|intact:MINT-142143|ensembl:ENSMUSP00000030893 intact:EBI-727171|uniprotkb:Q96I97|uniprotkb:Q9Y6C6|uniprotkb:Q5T6G6|uniprotkb:Q5T6G5|ensembl:ENSP00000366237 psi-mi:dffb_mouse(display_long)|uniprotkb:Dffb(gene name)|psi-mi:Dffb(display_short)|uniprotkb:Cad(gene name synonym)|uniprotkb:DNA fragmentation factor 40 kDa subunit(gene name synonym)|uniprotkb:Caspase-activated deoxyribonuclease(gene name synonym) psi-mi:dffa_human(display_long)|uniprotkb:DNA fragmentation factor 45 kDa subunit(gene name synonym)|uniprotkb:Inhibitor of CAD(gene name synonym)|uniprotkb:DFFA(gene name)|psi-mi:DFFA(display_short)|uniprotkb:DFF1(gene name synonym)|uniprotkb:DFF45(gene name synonym)|uniprotkb:H13(orf name) psi-mi:"MI:0081"(peptide array) Kutscher et al. (2012) pubmed:22727028|mint:MINT-8383086|mint:fj-12-0127.r1|doi:10.1111/j.1742-4658.2012.08673 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7937067|mint:MINT-8383156 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031885.3|ensembl:ENSMUSG00000029027(gene)|ensembl:ENSMUST00000030893(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006308"(DNA catabolic process)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015311(Apoptosis, DNA fragmentation factor 40 kDa)|interpro:IPR039729|mint:O54788|rcsb pdb:1C9F|rcsb pdb:1F2R|rcsb pdb:1V0D|reactome:R-MMU-140342|mint:MINT-8383158(identity) refseq:NP_004392.1|refseq:NP_998731.1|ensembl:ENSG00000160049(gene)|ensembl:ENST00000377038(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032076"(negative regulation of deoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0060703"(deoxyribonuclease inhibitor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015121(DNA Fragmentation factor 45kDa, C terminal)|interpro:IPR017299(DNA fragmentation factor, alpha subunit)|interpro:IPR027296|rcsb pdb:1IBX|rcsb pdb:1IYR|rcsb pdb:1KOY|reactome:R-HSA-140342|mint:MINT-8383160(identity) - comment:mint|function:Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology|comment:homomint - comment:homomint|comment:mint|figure legend:t2 f1B taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/19 2014/10/16 rogid:6BiQzdEqkkJvzK4tj/xdBvpkWKY10090 rogid:jz7MT9TaqFl1lwoITptPZ3P2KVY9606 intact-crc:1B786125E7CEBAB4|rigid:1TgFmQA53B6kfahaT3GhPjXl5eo false binding-associated region:1-50(MINT-8383169) - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O54788 uniprotkb:O00273 intact:EBI-7365197|intact:MINT-142143|ensembl:ENSMUSP00000030893 intact:EBI-727171|uniprotkb:Q96I97|uniprotkb:Q9Y6C6|uniprotkb:Q5T6G6|uniprotkb:Q5T6G5|ensembl:ENSP00000366237 psi-mi:dffb_mouse(display_long)|uniprotkb:Dffb(gene name)|psi-mi:Dffb(display_short)|uniprotkb:Cad(gene name synonym)|uniprotkb:DNA fragmentation factor 40 kDa subunit(gene name synonym)|uniprotkb:Caspase-activated deoxyribonuclease(gene name synonym) psi-mi:dffa_human(display_long)|uniprotkb:DNA fragmentation factor 45 kDa subunit(gene name synonym)|uniprotkb:Inhibitor of CAD(gene name synonym)|uniprotkb:DFFA(gene name)|psi-mi:DFFA(display_short)|uniprotkb:DFF1(gene name synonym)|uniprotkb:DFF45(gene name synonym)|uniprotkb:H13(orf name) psi-mi:"MI:0081"(peptide array) Kutscher et al. (2012) pubmed:22727028|mint:MINT-8383086|mint:fj-12-0127.r1|doi:10.1111/j.1742-4658.2012.08673 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7937123|mint:MINT-8383182 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031885.3|ensembl:ENSMUSG00000029027(gene)|ensembl:ENSMUST00000030893(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006308"(DNA catabolic process)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015311(Apoptosis, DNA fragmentation factor 40 kDa)|interpro:IPR039729|mint:O54788|rcsb pdb:1C9F|rcsb pdb:1F2R|rcsb pdb:1V0D|reactome:R-MMU-140342|mint:MINT-8383184(identity) refseq:NP_004392.1|refseq:NP_998731.1|ensembl:ENSG00000160049(gene)|ensembl:ENST00000377038(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032076"(negative regulation of deoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0060703"(deoxyribonuclease inhibitor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015121(DNA Fragmentation factor 45kDa, C terminal)|interpro:IPR017299(DNA fragmentation factor, alpha subunit)|interpro:IPR027296|rcsb pdb:1IBX|rcsb pdb:1IYR|rcsb pdb:1KOY|reactome:R-HSA-140342|mint:MINT-8383188(identity) - comment:mint|function:Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology|comment:homomint - comment:homomint|comment:mint|figure legend:t2 f1B taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/19 2014/10/16 rogid:6BiQzdEqkkJvzK4tj/xdBvpkWKY10090 rogid:jz7MT9TaqFl1lwoITptPZ3P2KVY9606 intact-crc:223572759D7B9211|rigid:1TgFmQA53B6kfahaT3GhPjXl5eo false binding-associated region:139-176(MINT-8383185) - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O54788 uniprotkb:O00273 intact:EBI-7365197|intact:MINT-142143|ensembl:ENSMUSP00000030893 intact:EBI-727171|uniprotkb:Q96I97|uniprotkb:Q9Y6C6|uniprotkb:Q5T6G6|uniprotkb:Q5T6G5|ensembl:ENSP00000366237 psi-mi:dffb_mouse(display_long)|uniprotkb:Dffb(gene name)|psi-mi:Dffb(display_short)|uniprotkb:Cad(gene name synonym)|uniprotkb:DNA fragmentation factor 40 kDa subunit(gene name synonym)|uniprotkb:Caspase-activated deoxyribonuclease(gene name synonym) psi-mi:dffa_human(display_long)|uniprotkb:DNA fragmentation factor 45 kDa subunit(gene name synonym)|uniprotkb:Inhibitor of CAD(gene name synonym)|uniprotkb:DFFA(gene name)|psi-mi:DFFA(display_short)|uniprotkb:DFF1(gene name synonym)|uniprotkb:DFF45(gene name synonym)|uniprotkb:H13(orf name) psi-mi:"MI:0081"(peptide array) Kutscher et al. (2012) pubmed:22727028|mint:MINT-8383086|mint:fj-12-0127.r1|doi:10.1111/j.1742-4658.2012.08673 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7937082|mint:MINT-8383172 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031885.3|ensembl:ENSMUSG00000029027(gene)|ensembl:ENSMUST00000030893(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006308"(DNA catabolic process)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015311(Apoptosis, DNA fragmentation factor 40 kDa)|interpro:IPR039729|mint:O54788|rcsb pdb:1C9F|rcsb pdb:1F2R|rcsb pdb:1V0D|reactome:R-MMU-140342|mint:MINT-8383174(identity) refseq:NP_004392.1|refseq:NP_998731.1|ensembl:ENSG00000160049(gene)|ensembl:ENST00000377038(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032076"(negative regulation of deoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0060703"(deoxyribonuclease inhibitor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015121(DNA Fragmentation factor 45kDa, C terminal)|interpro:IPR017299(DNA fragmentation factor, alpha subunit)|interpro:IPR027296|rcsb pdb:1IBX|rcsb pdb:1IYR|rcsb pdb:1KOY|reactome:R-HSA-140342|mint:MINT-8383178(identity) - comment:mint|function:Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology|comment:homomint - comment:homomint|comment:mint|figure legend:t2 f1B taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/19 2014/10/16 rogid:6BiQzdEqkkJvzK4tj/xdBvpkWKY10090 rogid:jz7MT9TaqFl1lwoITptPZ3P2KVY9606 intact-crc:57245FD132AD6E13|rigid:1TgFmQA53B6kfahaT3GhPjXl5eo false binding-associated region:91-134(MINT-8383175) - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O54788 uniprotkb:O00273 intact:EBI-7365197|intact:MINT-142143|ensembl:ENSMUSP00000030893 intact:EBI-727171|uniprotkb:Q96I97|uniprotkb:Q9Y6C6|uniprotkb:Q5T6G6|uniprotkb:Q5T6G5|ensembl:ENSP00000366237 psi-mi:dffb_mouse(display_long)|uniprotkb:Dffb(gene name)|psi-mi:Dffb(display_short)|uniprotkb:Cad(gene name synonym)|uniprotkb:DNA fragmentation factor 40 kDa subunit(gene name synonym)|uniprotkb:Caspase-activated deoxyribonuclease(gene name synonym) psi-mi:dffa_human(display_long)|uniprotkb:DNA fragmentation factor 45 kDa subunit(gene name synonym)|uniprotkb:Inhibitor of CAD(gene name synonym)|uniprotkb:DFFA(gene name)|psi-mi:DFFA(display_short)|uniprotkb:DFF1(gene name synonym)|uniprotkb:DFF45(gene name synonym)|uniprotkb:H13(orf name) psi-mi:"MI:0081"(peptide array) Kutscher et al. (2012) pubmed:22727028|mint:MINT-8383086|mint:fj-12-0127.r1|doi:10.1111/j.1742-4658.2012.08673 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7937189|mint:MINT-8383202 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031885.3|ensembl:ENSMUSG00000029027(gene)|ensembl:ENSMUST00000030893(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006308"(DNA catabolic process)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015311(Apoptosis, DNA fragmentation factor 40 kDa)|interpro:IPR039729|mint:O54788|rcsb pdb:1C9F|rcsb pdb:1F2R|rcsb pdb:1V0D|reactome:R-MMU-140342|mint:MINT-8383204(identity) refseq:NP_004392.1|refseq:NP_998731.1|ensembl:ENSG00000160049(gene)|ensembl:ENST00000377038(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032076"(negative regulation of deoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0060703"(deoxyribonuclease inhibitor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015121(DNA Fragmentation factor 45kDa, C terminal)|interpro:IPR017299(DNA fragmentation factor, alpha subunit)|interpro:IPR027296|rcsb pdb:1IBX|rcsb pdb:1IYR|rcsb pdb:1KOY|reactome:R-HSA-140342|mint:MINT-8383208(identity) - comment:mint|function:Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology|comment:homomint - comment:homomint|comment:mint|figure legend:t2 f1B taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/19 2014/10/16 rogid:6BiQzdEqkkJvzK4tj/xdBvpkWKY10090 rogid:jz7MT9TaqFl1lwoITptPZ3P2KVY9606 intact-crc:98EC3117A51A60DD|rigid:1TgFmQA53B6kfahaT3GhPjXl5eo false binding-associated region:223-260(MINT-8383205) - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O54788 uniprotkb:O00273 intact:EBI-7365197|intact:MINT-142143|ensembl:ENSMUSP00000030893 intact:EBI-727171|uniprotkb:Q96I97|uniprotkb:Q9Y6C6|uniprotkb:Q5T6G6|uniprotkb:Q5T6G5|ensembl:ENSP00000366237 psi-mi:dffb_mouse(display_long)|uniprotkb:Dffb(gene name)|psi-mi:Dffb(display_short)|uniprotkb:Cad(gene name synonym)|uniprotkb:DNA fragmentation factor 40 kDa subunit(gene name synonym)|uniprotkb:Caspase-activated deoxyribonuclease(gene name synonym) psi-mi:dffa_human(display_long)|uniprotkb:DNA fragmentation factor 45 kDa subunit(gene name synonym)|uniprotkb:Inhibitor of CAD(gene name synonym)|uniprotkb:DFFA(gene name)|psi-mi:DFFA(display_short)|uniprotkb:DFF1(gene name synonym)|uniprotkb:DFF45(gene name synonym)|uniprotkb:H13(orf name) psi-mi:"MI:0081"(peptide array) Kutscher et al. (2012) pubmed:22727028|mint:MINT-8383086|mint:fj-12-0127.r1|doi:10.1111/j.1742-4658.2012.08673 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7937230|mint:MINT-8383212 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031885.3|ensembl:ENSMUSG00000029027(gene)|ensembl:ENSMUST00000030893(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006308"(DNA catabolic process)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015311(Apoptosis, DNA fragmentation factor 40 kDa)|interpro:IPR039729|mint:O54788|rcsb pdb:1C9F|rcsb pdb:1F2R|rcsb pdb:1V0D|reactome:R-MMU-140342|mint:MINT-8383214(identity) refseq:NP_004392.1|refseq:NP_998731.1|ensembl:ENSG00000160049(gene)|ensembl:ENST00000377038(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032076"(negative regulation of deoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0060703"(deoxyribonuclease inhibitor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015121(DNA Fragmentation factor 45kDa, C terminal)|interpro:IPR017299(DNA fragmentation factor, alpha subunit)|interpro:IPR027296|rcsb pdb:1IBX|rcsb pdb:1IYR|rcsb pdb:1KOY|reactome:R-HSA-140342|mint:MINT-8383218(identity) - comment:mint|function:Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology|comment:homomint - comment:homomint|comment:mint|figure legend:t2 f1B taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/19 2014/10/16 rogid:6BiQzdEqkkJvzK4tj/xdBvpkWKY10090 rogid:jz7MT9TaqFl1lwoITptPZ3P2KVY9606 intact-crc:13B0CAAFA77B8D04|rigid:1TgFmQA53B6kfahaT3GhPjXl5eo false binding-associated region:265-284(MINT-8383215) - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O54788 uniprotkb:O00273 intact:EBI-7365197|intact:MINT-142143|ensembl:ENSMUSP00000030893 intact:EBI-727171|uniprotkb:Q96I97|uniprotkb:Q9Y6C6|uniprotkb:Q5T6G6|uniprotkb:Q5T6G5|ensembl:ENSP00000366237 psi-mi:dffb_mouse(display_long)|uniprotkb:Dffb(gene name)|psi-mi:Dffb(display_short)|uniprotkb:Cad(gene name synonym)|uniprotkb:DNA fragmentation factor 40 kDa subunit(gene name synonym)|uniprotkb:Caspase-activated deoxyribonuclease(gene name synonym) psi-mi:dffa_human(display_long)|uniprotkb:DNA fragmentation factor 45 kDa subunit(gene name synonym)|uniprotkb:Inhibitor of CAD(gene name synonym)|uniprotkb:DFFA(gene name)|psi-mi:DFFA(display_short)|uniprotkb:DFF1(gene name synonym)|uniprotkb:DFF45(gene name synonym)|uniprotkb:H13(orf name) psi-mi:"MI:0081"(peptide array) Kutscher et al. (2012) pubmed:22727028|mint:MINT-8383086|mint:fj-12-0127.r1|doi:10.1111/j.1742-4658.2012.08673 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7937150|mint:MINT-8383192 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031885.3|ensembl:ENSMUSG00000029027(gene)|ensembl:ENSMUST00000030893(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006308"(DNA catabolic process)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015311(Apoptosis, DNA fragmentation factor 40 kDa)|interpro:IPR039729|mint:O54788|rcsb pdb:1C9F|rcsb pdb:1F2R|rcsb pdb:1V0D|reactome:R-MMU-140342|mint:MINT-8383194(identity) refseq:NP_004392.1|refseq:NP_998731.1|ensembl:ENSG00000160049(gene)|ensembl:ENST00000377038(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032076"(negative regulation of deoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0060703"(deoxyribonuclease inhibitor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015121(DNA Fragmentation factor 45kDa, C terminal)|interpro:IPR017299(DNA fragmentation factor, alpha subunit)|interpro:IPR027296|rcsb pdb:1IBX|rcsb pdb:1IYR|rcsb pdb:1KOY|reactome:R-HSA-140342|mint:MINT-8383198(identity) - comment:mint|function:Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology|comment:homomint - comment:homomint|comment:mint|figure legend:t2 f1B taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/19 2014/10/16 rogid:6BiQzdEqkkJvzK4tj/xdBvpkWKY10090 rogid:jz7MT9TaqFl1lwoITptPZ3P2KVY9606 intact-crc:43F1DE23AE80E9BC|rigid:1TgFmQA53B6kfahaT3GhPjXl5eo false binding-associated region:187-218(MINT-8383195) - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O54788 uniprotkb:O00273 intact:EBI-7365197|intact:MINT-142143|ensembl:ENSMUSP00000030893 intact:EBI-727171|uniprotkb:Q96I97|uniprotkb:Q9Y6C6|uniprotkb:Q5T6G6|uniprotkb:Q5T6G5|ensembl:ENSP00000366237 psi-mi:dffb_mouse(display_long)|uniprotkb:Dffb(gene name)|psi-mi:Dffb(display_short)|uniprotkb:Cad(gene name synonym)|uniprotkb:DNA fragmentation factor 40 kDa subunit(gene name synonym)|uniprotkb:Caspase-activated deoxyribonuclease(gene name synonym) psi-mi:dffa_human(display_long)|uniprotkb:DNA fragmentation factor 45 kDa subunit(gene name synonym)|uniprotkb:Inhibitor of CAD(gene name synonym)|uniprotkb:DFFA(gene name)|psi-mi:DFFA(display_short)|uniprotkb:DFF1(gene name synonym)|uniprotkb:DFF45(gene name synonym)|uniprotkb:H13(orf name) psi-mi:"MI:0081"(peptide array) Kutscher et al. (2012) pubmed:22727028|mint:MINT-8383086|mint:fj-12-0127.r1|doi:10.1111/j.1742-4658.2012.08673 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7937263|mint:MINT-8383222 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031885.3|ensembl:ENSMUSG00000029027(gene)|ensembl:ENSMUST00000030893(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006308"(DNA catabolic process)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015311(Apoptosis, DNA fragmentation factor 40 kDa)|interpro:IPR039729|mint:O54788|rcsb pdb:1C9F|rcsb pdb:1F2R|rcsb pdb:1V0D|reactome:R-MMU-140342|mint:MINT-8383224(identity) refseq:NP_004392.1|refseq:NP_998731.1|ensembl:ENSG00000160049(gene)|ensembl:ENST00000377038(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032076"(negative regulation of deoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0060703"(deoxyribonuclease inhibitor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015121(DNA Fragmentation factor 45kDa, C terminal)|interpro:IPR017299(DNA fragmentation factor, alpha subunit)|interpro:IPR027296|rcsb pdb:1IBX|rcsb pdb:1IYR|rcsb pdb:1KOY|reactome:R-HSA-140342|mint:MINT-8383228(identity) - comment:mint|function:Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology|comment:homomint - comment:homomint|comment:mint|figure legend:t2 f1B taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/19 2014/10/16 rogid:6BiQzdEqkkJvzK4tj/xdBvpkWKY10090 rogid:jz7MT9TaqFl1lwoITptPZ3P2KVY9606 intact-crc:8DD7882652048DF2|rigid:1TgFmQA53B6kfahaT3GhPjXl5eo false binding-associated region:289-344(MINT-8383225) - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O54788 uniprotkb:O00273 intact:EBI-7365197|intact:MINT-142143|ensembl:ENSMUSP00000030893 intact:EBI-727171|uniprotkb:Q96I97|uniprotkb:Q9Y6C6|uniprotkb:Q5T6G6|uniprotkb:Q5T6G5|ensembl:ENSP00000366237 psi-mi:dffb_mouse(display_long)|uniprotkb:Dffb(gene name)|psi-mi:Dffb(display_short)|uniprotkb:Cad(gene name synonym)|uniprotkb:DNA fragmentation factor 40 kDa subunit(gene name synonym)|uniprotkb:Caspase-activated deoxyribonuclease(gene name synonym) psi-mi:dffa_human(display_long)|uniprotkb:DNA fragmentation factor 45 kDa subunit(gene name synonym)|uniprotkb:Inhibitor of CAD(gene name synonym)|uniprotkb:DFFA(gene name)|psi-mi:DFFA(display_short)|uniprotkb:DFF1(gene name synonym)|uniprotkb:DFF45(gene name synonym)|uniprotkb:H13(orf name) psi-mi:"MI:0081"(peptide array) Kutscher et al. (2012) pubmed:22727028|mint:MINT-8383086|mint:fj-12-0127.r1|doi:10.1111/j.1742-4658.2012.08673 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7937296|mint:MINT-8383232 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031885.3|ensembl:ENSMUSG00000029027(gene)|ensembl:ENSMUST00000030893(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006308"(DNA catabolic process)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015311(Apoptosis, DNA fragmentation factor 40 kDa)|interpro:IPR039729|mint:O54788|rcsb pdb:1C9F|rcsb pdb:1F2R|rcsb pdb:1V0D|reactome:R-MMU-140342|mint:MINT-8383234(identity) refseq:NP_004392.1|refseq:NP_998731.1|ensembl:ENSG00000160049(gene)|ensembl:ENST00000377038(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032076"(negative regulation of deoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0060703"(deoxyribonuclease inhibitor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015121(DNA Fragmentation factor 45kDa, C terminal)|interpro:IPR017299(DNA fragmentation factor, alpha subunit)|interpro:IPR027296|rcsb pdb:1IBX|rcsb pdb:1IYR|rcsb pdb:1KOY|reactome:R-HSA-140342|mint:MINT-8383238(identity) - comment:mint|function:Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology|comment:homomint - comment:homomint|comment:mint|figure legend:t2 f1B taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/19 2014/10/16 rogid:6BiQzdEqkkJvzK4tj/xdBvpkWKY10090 rogid:jz7MT9TaqFl1lwoITptPZ3P2KVY9606 intact-crc:1E790DC728840A93|rigid:1TgFmQA53B6kfahaT3GhPjXl5eo false binding-associated region:253-272(MINT-8383235) - - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O54788 uniprotkb:O54786 intact:EBI-7365197|intact:MINT-142143|ensembl:ENSMUSP00000030893 intact:EBI-1634519|uniprotkb:O54787|uniprotkb:Q8BQC7|uniprotkb:B2KFX0|ensembl:ENSMUSP00000030816 psi-mi:dffb_mouse(display_long)|uniprotkb:Dffb(gene name)|psi-mi:Dffb(display_short)|uniprotkb:Cad(gene name synonym)|uniprotkb:DNA fragmentation factor 40 kDa subunit(gene name synonym)|uniprotkb:Caspase-activated deoxyribonuclease(gene name synonym) psi-mi:dffa_mouse(display_long)|uniprotkb:Dffa(gene name)|psi-mi:Dffa(display_short)|uniprotkb:Icad(gene name synonym)|uniprotkb:DNA fragmentation factor 45 kDa subunit(gene name synonym)|uniprotkb:Inhibitor of CAD(gene name synonym) psi-mi:"MI:0081"(peptide array) Kutscher et al. (2012) pubmed:22727028|mint:MINT-8383086|mint:fj-12-0127.r1|doi:10.1111/j.1742-4658.2012.08673 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7937332|mint:MINT-8383261 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031885.3|ensembl:ENSMUSG00000029027(gene)|ensembl:ENSMUST00000030893(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006308"(DNA catabolic process)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015311(Apoptosis, DNA fragmentation factor 40 kDa)|interpro:IPR039729|mint:O54788|rcsb pdb:1C9F|rcsb pdb:1F2R|rcsb pdb:1V0D|reactome:R-MMU-140342|mint:MINT-8383263(identity) refseq:NP_001020467.1|ensembl:ENSMUSG00000028974(gene)|ensembl:ENSMUST00000030816(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006309"(apoptotic DNA fragmentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032076"(negative regulation of deoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0060703"(deoxyribonuclease inhibitor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:1900118"(negative regulation of execution phase of apoptosis)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|interpro:IPR003508(Caspase-activated nuclease CIDE-N)|interpro:IPR015121(DNA Fragmentation factor 45kDa, C terminal)|interpro:IPR017299(DNA fragmentation factor, alpha subunit)|interpro:IPR027296|rcsb pdb:1F2R|reactome:R-MMU-140342|mint:MINT-8383265(identity) - comment:mint|function:Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology|comment:homomint - comment:homomint|comment:mint|figure legend:t1 f1a taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/06/19 2014/10/16 rogid:6BiQzdEqkkJvzK4tj/xdBvpkWKY10090 rogid:MVg3+6pxmmcKBjFz1apoG3Di0Ig10090 intact-crc:C1D12CCDAD7765EE|rigid:88YVovLIn19pXwYxS3t6DpLSqHw false - binding-associated region:289-330(MINT-8383266) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0083"(peptide synthesis)