#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P06276	uniprotkb:P06276	intact:EBI-7936069|uniprotkb:A8K7P8|intact:UNK-5369911|ensembl:ENSP00000264381	intact:EBI-7936069|uniprotkb:A8K7P8|intact:UNK-5369911|ensembl:ENSP00000264381	psi-mi:chle_human(display_long)|uniprotkb:BCHE(gene name)|psi-mi:BCHE(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:Acylcholine acylhydrolase(gene name synonym)|uniprotkb:Choline esterase II(gene name synonym)|uniprotkb:Butyrylcholine esterase(gene name synonym)|uniprotkb:Pseudocholinesterase(gene name synonym)	psi-mi:chle_human(display_long)|uniprotkb:BCHE(gene name)|psi-mi:BCHE(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:Acylcholine acylhydrolase(gene name synonym)|uniprotkb:Choline esterase II(gene name synonym)|uniprotkb:Butyrylcholine esterase(gene name synonym)|uniprotkb:Pseudocholinesterase(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Brazzolotto et al. (2012)	pubmed:22726956|mint:MINT-8383070	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7936141|mint:MINT-8383075	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000046.1|dip:DIP-46476N|ensembl:ENSG00000114200(gene)|ensembl:ENST00000264381(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0003824"(catalytic activity)|go:"GO:0003990"(acetylcholinesterase activity)|go:"GO:0004104"(cholinesterase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007612"(learning)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014016"(neuroblast differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0019695"(choline metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0033265"(choline binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043279"(response to alkaloid)|go:"GO:0050783"(cocaine metabolic process)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051593"(response to folic acid)|go:"GO:0072562"(blood microparticle)|interpro:IPR000997(Cholinesterase)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR014788(Acetylcholinesterase, tetramerisation)|interpro:IPR019819|interpro:IPR019826|interpro:IPR029058|rcsb pdb:1EHO|rcsb pdb:1EHQ|rcsb pdb:1KCJ|rcsb pdb:1P0I|rcsb pdb:1P0M|rcsb pdb:1P0P|rcsb pdb:1P0Q|rcsb pdb:1XLU|rcsb pdb:1XLV|rcsb pdb:1XLW|rcsb pdb:2J4C|rcsb pdb:2PM8|rcsb pdb:2WID|rcsb pdb:2WIF|rcsb pdb:2WIG|rcsb pdb:2WIJ|rcsb pdb:2WIK|rcsb pdb:2WIL|rcsb pdb:2WSL|rcsb pdb:2XMB|rcsb pdb:2XMC|rcsb pdb:2XMD|rcsb pdb:2XMG|rcsb pdb:2XQF|rcsb pdb:2XQG|rcsb pdb:2XQI|rcsb pdb:2XQJ|rcsb pdb:2XQK|rcsb pdb:2Y1K|rcsb pdb:3DJY|rcsb pdb:3DKK|rcsb pdb:3O9M|rcsb pdb:4AQD|rcsb pdb:4AXB|rcsb pdb:4B0O|rcsb pdb:4B0P|rcsb pdb:4BBZ|rcsb pdb:4BDS|rcsb pdb:4TPK|rcsb pdb:4XII|rcsb pdb:5DYT|rcsb pdb:5DYW|rcsb pdb:5K5E|rcsb pdb:5LKR|rcsb pdb:5NN0|rcsb pdb:6EMI|rcsb pdb:6EP4|rcsb pdb:6EQP|rcsb pdb:6EQQ|rcsb pdb:6ESJ|rcsb pdb:6ESY|rcsb pdb:6EUL|rcsb pdb:6EYF|rcsb pdb:6EZ2|rcsb pdb:6F7Q|rcsb pdb:6I0B|rcsb pdb:6I0C|rcsb pdb:6I2T|rcsb pdb:6QAA|rcsb pdb:6QAB|rcsb pdb:6QAC|rcsb pdb:6QAD|rcsb pdb:6QAE|rcsb pdb:6R6V|rcsb pdb:6R6W|rcsb pdb:6RUA|rcsb pdb:6SAM|rcsb pdb:6T9P|rcsb pdb:6T9S|rcsb pdb:6XTA|rcsb pdb:6ZWI|rcsb pdb:7AMZ|rcsb pdb:7BGC|reactome:R-HSA-112311|reactome:R-HSA-1483191|reactome:R-HSA-422085|rcsb pdb:5DYY|mint:MINT-8383077(identity)	refseq:NP_000046.1|dip:DIP-46476N|ensembl:ENSG00000114200(gene)|ensembl:ENST00000264381(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0003824"(catalytic activity)|go:"GO:0003990"(acetylcholinesterase activity)|go:"GO:0004104"(cholinesterase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007612"(learning)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014016"(neuroblast differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0019695"(choline metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0033265"(choline binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043279"(response to alkaloid)|go:"GO:0050783"(cocaine metabolic process)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051593"(response to folic acid)|go:"GO:0072562"(blood microparticle)|interpro:IPR000997(Cholinesterase)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR014788(Acetylcholinesterase, tetramerisation)|interpro:IPR019819|interpro:IPR019826|interpro:IPR029058|rcsb pdb:1EHO|rcsb pdb:1EHQ|rcsb pdb:1KCJ|rcsb pdb:1P0I|rcsb pdb:1P0M|rcsb pdb:1P0P|rcsb pdb:1P0Q|rcsb pdb:1XLU|rcsb pdb:1XLV|rcsb pdb:1XLW|rcsb pdb:2J4C|rcsb pdb:2PM8|rcsb pdb:2WID|rcsb pdb:2WIF|rcsb pdb:2WIG|rcsb pdb:2WIJ|rcsb pdb:2WIK|rcsb pdb:2WIL|rcsb pdb:2WSL|rcsb pdb:2XMB|rcsb pdb:2XMC|rcsb pdb:2XMD|rcsb pdb:2XMG|rcsb pdb:2XQF|rcsb pdb:2XQG|rcsb pdb:2XQI|rcsb pdb:2XQJ|rcsb pdb:2XQK|rcsb pdb:2Y1K|rcsb pdb:3DJY|rcsb pdb:3DKK|rcsb pdb:3O9M|rcsb pdb:4AQD|rcsb pdb:4AXB|rcsb pdb:4B0O|rcsb pdb:4B0P|rcsb pdb:4BBZ|rcsb pdb:4BDS|rcsb pdb:4TPK|rcsb pdb:4XII|rcsb pdb:5DYT|rcsb pdb:5DYW|rcsb pdb:5K5E|rcsb pdb:5LKR|rcsb pdb:5NN0|rcsb pdb:6EMI|rcsb pdb:6EP4|rcsb pdb:6EQP|rcsb pdb:6EQQ|rcsb pdb:6ESJ|rcsb pdb:6ESY|rcsb pdb:6EUL|rcsb pdb:6EYF|rcsb pdb:6EZ2|rcsb pdb:6F7Q|rcsb pdb:6I0B|rcsb pdb:6I0C|rcsb pdb:6I2T|rcsb pdb:6QAA|rcsb pdb:6QAB|rcsb pdb:6QAC|rcsb pdb:6QAD|rcsb pdb:6QAE|rcsb pdb:6R6V|rcsb pdb:6R6W|rcsb pdb:6RUA|rcsb pdb:6SAM|rcsb pdb:6T9P|rcsb pdb:6T9S|rcsb pdb:6XTA|rcsb pdb:6ZWI|rcsb pdb:7AMZ|rcsb pdb:7BGC|reactome:R-HSA-112311|reactome:R-HSA-1483191|reactome:R-HSA-422085|rcsb pdb:5DYY|mint:MINT-8383077(identity)	-	function:"Defects in BCHE are the cause of butyrylcholinesterase deficiency (BChE deficiency) [MIM:177400]. BChE deficiency is a metabolic disorder characterized by prolonged apnoea after the use of certain anesthetic drugs, including the muscle relaxants succinylcholine or mivacurium and other ester local anesthetics. The duration of the prolonged apnoea varies significantly depending on the extent of the enzyme deficiency. BChE deficiency is a multifactorial disorder. The hereditary condition is transmitted as an autosomal recessive trait"|comment:mint|comment:"Stoichiometry: 2.0"	function:"Defects in BCHE are the cause of butyrylcholinesterase deficiency (BChE deficiency) [MIM:177400]. BChE deficiency is a metabolic disorder characterized by prolonged apnoea after the use of certain anesthetic drugs, including the muscle relaxants succinylcholine or mivacurium and other ester local anesthetics. The duration of the prolonged apnoea varies significantly depending on the extent of the enzyme deficiency. BChE deficiency is a multifactorial disorder. The hereditary condition is transmitted as an autosomal recessive trait"|comment:mint|comment:"Stoichiometry: 2.0"	comment:mint|figure legend:t4 f1 f2	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/06/18	2014/10/16	rogid:fQ8iZuf4Z3jU7o4Dpb1OXO6r6Po9606	rogid:fQ8iZuf4Z3jU7o4Dpb1OXO6r6Po9606	intact-crc:3F541AB0DDC8B572|rigid:2duY624puMHFMEkBhQAlrhT5PxM	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)