#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q64321 uniprotkb:O88895 intact:EBI-642868|uniprotkb:Q80VV5|ensembl:ENSMUSP00000103055|ensembl:ENSMUSP00000103056|ensembl:ENSMUSP00000103058|ensembl:ENSMUSP00000029677 intact:EBI-302263|uniprotkb:O88896 psi-mi:zbt7b_mouse(display_long)|uniprotkb:Zinc finger protein 67(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:Zbtb7b(gene name)|psi-mi:Zbtb7b(display_short)|uniprotkb:Thpok(gene name synonym)|uniprotkb:Zfp67(gene name synonym) psi-mi:hdac3_mouse(display_long)|uniprotkb:Hdac3(gene name)|psi-mi:Hdac3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zullo et al. (2012) pubmed:22726435|imex:IM-17379 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6172093|imex:IM-17379-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033591.2|refseq:XP_006501376.1|refseq:XP_006501377.1|refseq:XP_006501379.1|refseq:XP_006501380.1|refseq:XP_006501381.1|refseq:XP_006501382.1|ensembl:ENSMUSG00000028042(gene)|ensembl:ENSMUST00000029677(transcript)|ensembl:ENSMUST00000107432(transcript)|ensembl:ENSMUST00000107433(transcript)|ensembl:ENSMUST00000107435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001865"(NK T cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007595"(lactation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032868"(response to insulin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:0043370"(regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043376"(regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0043377"(negative regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000640"(positive regulation of SREBP signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000210(BTB/POZ-like)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0051141"(negative regulation of NK T cell proliferation)|interpro:IPR011333(BTB/POZ fold)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q64321 go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032692"(negative regulation of interleukin-1 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0051020"(GTPase binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990679"(histone H4-K12 deacetylation)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000726"(negative regulation of cardiac muscle cell differentiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-400206|reactome:R-MMU-9029569|reactome:R-MMU-9707564|dip:DIP-32547N|mint:O88895 - - - figure legend:Fig. 6A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2012/07/03 2014/10/16 rogid:sU1MIrKZnvkMEoOdVf75ZNnmwoQ10090 rogid:0dUkbfmVE49cbSiAPqrb7uFN8l010090 intact-crc:F61DD4EDDBA61060|rigid:5jAEBtJX4j7KqtzXrxX15xc5oQo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q64321 uniprotkb:Q61029 intact:EBI-642868|uniprotkb:Q80VV5|ensembl:ENSMUSP00000103055|ensembl:ENSMUSP00000103056|ensembl:ENSMUSP00000103058|ensembl:ENSMUSP00000029677 intact:EBI-6172136|ensembl:ENSMUSP00000072092|uniprotkb:Q3UCI5|uniprotkb:Q61030|uniprotkb:Q61031|uniprotkb:Q61032 psi-mi:zbt7b_mouse(display_long)|uniprotkb:Zinc finger protein 67(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:Zbtb7b(gene name)|psi-mi:Zbtb7b(display_short)|uniprotkb:Thpok(gene name synonym)|uniprotkb:Zfp67(gene name synonym) psi-mi:lap2b_mouse(display_long)|uniprotkb:Tmpo(gene name)|psi-mi:Tmpo(display_short)|uniprotkb:Lap2(gene name synonym)|uniprotkb:Thymopoietin isoforms beta/delta/epsilon/gamma(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zullo et al. (2012) pubmed:22726435|imex:IM-17379 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6172093|imex:IM-17379-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033591.2|refseq:XP_006501376.1|refseq:XP_006501377.1|refseq:XP_006501379.1|refseq:XP_006501380.1|refseq:XP_006501381.1|refseq:XP_006501382.1|ensembl:ENSMUSG00000028042(gene)|ensembl:ENSMUST00000029677(transcript)|ensembl:ENSMUST00000107432(transcript)|ensembl:ENSMUST00000107433(transcript)|ensembl:ENSMUST00000107435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001865"(NK T cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007595"(lactation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032868"(response to insulin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:0043370"(regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043376"(regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0043377"(negative regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000640"(positive regulation of SREBP signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000210(BTB/POZ-like)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0051141"(negative regulation of NK T cell proliferation)|interpro:IPR011333(BTB/POZ fold)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q64321 ensembl:ENSMUSG00000019961(gene)|ensembl:ENSMUST00000072239(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|mint:Q61029|refseq:NP_001073598.1|refseq:NP_001073600.1|refseq:NP_001073601.1 - - - figure legend:Fig. 6A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2012/07/03 2014/10/16 rogid:sU1MIrKZnvkMEoOdVf75ZNnmwoQ10090 rogid:Gjr5NZyUa8Moc4L8lJlRPq29mQE10090 intact-crc:F61DD4EDDBA61060|rigid:5jAEBtJX4j7KqtzXrxX15xc5oQo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O88895 uniprotkb:Q61029 intact:EBI-302263|uniprotkb:O88896 intact:EBI-6172136|ensembl:ENSMUSP00000072092|uniprotkb:Q3UCI5|uniprotkb:Q61030|uniprotkb:Q61031|uniprotkb:Q61032 psi-mi:hdac3_mouse(display_long)|uniprotkb:Hdac3(gene name)|psi-mi:Hdac3(display_short) psi-mi:lap2b_mouse(display_long)|uniprotkb:Tmpo(gene name)|psi-mi:Tmpo(display_short)|uniprotkb:Lap2(gene name synonym)|uniprotkb:Thymopoietin isoforms beta/delta/epsilon/gamma(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zullo et al. (2012) pubmed:22726435|imex:IM-17379 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6172144|imex:IM-17379-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032692"(negative regulation of interleukin-1 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0051020"(GTPase binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990679"(histone H4-K12 deacetylation)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000726"(negative regulation of cardiac muscle cell differentiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-400206|reactome:R-MMU-9029569|reactome:R-MMU-9707564|dip:DIP-32547N|mint:O88895 ensembl:ENSMUSG00000019961(gene)|ensembl:ENSMUST00000072239(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|mint:Q61029|refseq:NP_001073598.1|refseq:NP_001073600.1|refseq:NP_001073601.1 - - - figure legend:Fig. 6A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2012/07/03 2014/10/16 rogid:0dUkbfmVE49cbSiAPqrb7uFN8l010090 rogid:Gjr5NZyUa8Moc4L8lJlRPq29mQE10090 intact-crc:92417F187EC2A185|rigid:wudZuL1PgBOX5y9wAwFxCKkBCtU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q64321 uniprotkb:Q61029 intact:EBI-642868|uniprotkb:Q80VV5|ensembl:ENSMUSP00000103055|ensembl:ENSMUSP00000103056|ensembl:ENSMUSP00000103058|ensembl:ENSMUSP00000029677 intact:EBI-6172136|ensembl:ENSMUSP00000072092|uniprotkb:Q3UCI5|uniprotkb:Q61030|uniprotkb:Q61031|uniprotkb:Q61032 psi-mi:zbt7b_mouse(display_long)|uniprotkb:Zinc finger protein 67(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:Zbtb7b(gene name)|psi-mi:Zbtb7b(display_short)|uniprotkb:Thpok(gene name synonym)|uniprotkb:Zfp67(gene name synonym) psi-mi:lap2b_mouse(display_long)|uniprotkb:Tmpo(gene name)|psi-mi:Tmpo(display_short)|uniprotkb:Lap2(gene name synonym)|uniprotkb:Thymopoietin isoforms beta/delta/epsilon/gamma(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zullo et al. (2012) pubmed:22726435|imex:IM-17379 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6172140|imex:IM-17379-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033591.2|refseq:XP_006501376.1|refseq:XP_006501377.1|refseq:XP_006501379.1|refseq:XP_006501380.1|refseq:XP_006501381.1|refseq:XP_006501382.1|ensembl:ENSMUSG00000028042(gene)|ensembl:ENSMUST00000029677(transcript)|ensembl:ENSMUST00000107432(transcript)|ensembl:ENSMUST00000107433(transcript)|ensembl:ENSMUST00000107435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001865"(NK T cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007595"(lactation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032868"(response to insulin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:0043370"(regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043376"(regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0043377"(negative regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000640"(positive regulation of SREBP signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000210(BTB/POZ-like)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0051141"(negative regulation of NK T cell proliferation)|interpro:IPR011333(BTB/POZ fold)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q64321 ensembl:ENSMUSG00000019961(gene)|ensembl:ENSMUST00000072239(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|mint:Q61029|refseq:NP_001073598.1|refseq:NP_001073600.1|refseq:NP_001073601.1 - - - figure legend:Fig. 6A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2012/07/03 2014/10/16 rogid:sU1MIrKZnvkMEoOdVf75ZNnmwoQ10090 rogid:Gjr5NZyUa8Moc4L8lJlRPq29mQE10090 intact-crc:01A82894F4F1DF55|rigid:EKPv3vkAoJl2yLE0Craf6rnRJFw false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-6171956 uniprotkb:Q64321 - intact:EBI-642868|uniprotkb:Q80VV5|ensembl:ENSMUSP00000103055|ensembl:ENSMUSP00000103056|ensembl:ENSMUSP00000103058|ensembl:ENSMUSP00000029677 psi-mi:igh_mouse_dna_1.1(display_short)|psi-mi:EBI-6171956(display_long) psi-mi:zbt7b_mouse(display_long)|uniprotkb:Zinc finger protein 67(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:Zbtb7b(gene name)|psi-mi:Zbtb7b(display_short)|uniprotkb:Thpok(gene name synonym)|uniprotkb:Zfp67(gene name synonym) psi-mi:"MI:0412"(electrophoretic mobility supershift assay) Zullo et al. (2012) pubmed:22726435|imex:IM-17379 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6171976|imex:IM-17379-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_033591.2|refseq:XP_006501376.1|refseq:XP_006501377.1|refseq:XP_006501379.1|refseq:XP_006501380.1|refseq:XP_006501381.1|refseq:XP_006501382.1|ensembl:ENSMUSG00000028042(gene)|ensembl:ENSMUST00000029677(transcript)|ensembl:ENSMUST00000107432(transcript)|ensembl:ENSMUST00000107433(transcript)|ensembl:ENSMUST00000107435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001865"(NK T cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007595"(lactation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032868"(response to insulin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:0043370"(regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043376"(regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0043377"(negative regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000640"(positive regulation of SREBP signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000210(BTB/POZ-like)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0051141"(negative regulation of NK T cell proliferation)|interpro:IPR011333(BTB/POZ fold)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q64321 - - - figure legend:Fig. 5C|comment:The complexes were supershifted with an anti-Myc antibody and were not formed if the GAGA motif was mutated to CACA|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/07/03 2014/10/16 - rogid:sU1MIrKZnvkMEoOdVf75ZNnmwoQ10090 intact-crc:0805E5BA7D61CB55 false biotin tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) intact:EBI-6171954 uniprotkb:Q64321 - intact:EBI-642868|uniprotkb:Q80VV5|ensembl:ENSMUSP00000103055|ensembl:ENSMUSP00000103056|ensembl:ENSMUSP00000103058|ensembl:ENSMUSP00000029677 psi-mi:cyp3a_mouse_dna_5.1(display_short)|psi-mi:EBI-6171954(display_long) psi-mi:zbt7b_mouse(display_long)|uniprotkb:Zinc finger protein 67(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:Zbtb7b(gene name)|psi-mi:Zbtb7b(display_short)|uniprotkb:Thpok(gene name synonym)|uniprotkb:Zfp67(gene name synonym) psi-mi:"MI:0412"(electrophoretic mobility supershift assay) Zullo et al. (2012) pubmed:22726435|imex:IM-17379 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6171967|imex:IM-17379-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_033591.2|refseq:XP_006501376.1|refseq:XP_006501377.1|refseq:XP_006501379.1|refseq:XP_006501380.1|refseq:XP_006501381.1|refseq:XP_006501382.1|ensembl:ENSMUSG00000028042(gene)|ensembl:ENSMUST00000029677(transcript)|ensembl:ENSMUST00000107432(transcript)|ensembl:ENSMUST00000107433(transcript)|ensembl:ENSMUST00000107435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001865"(NK T cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007595"(lactation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032868"(response to insulin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:0043370"(regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043376"(regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0043377"(negative regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000640"(positive regulation of SREBP signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000210(BTB/POZ-like)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0051141"(negative regulation of NK T cell proliferation)|interpro:IPR011333(BTB/POZ fold)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q64321 - - - figure legend:Fig. 5C|comment:The complexes were supershifted with an anti-Myc antibody and were not formed if the GAGA motif was mutated to CACA|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/07/03 2014/10/16 - rogid:sU1MIrKZnvkMEoOdVf75ZNnmwoQ10090 intact-crc:4DB1E59AD1007095 false biotin tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q64321 intact:EBI-6172014 intact:EBI-642868|uniprotkb:Q80VV5|ensembl:ENSMUSP00000103055|ensembl:ENSMUSP00000103056|ensembl:ENSMUSP00000103058|ensembl:ENSMUSP00000029677 - psi-mi:zbt7b_mouse(display_long)|uniprotkb:Zinc finger protein 67(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:Zbtb7b(gene name)|psi-mi:Zbtb7b(display_short)|uniprotkb:Thpok(gene name synonym)|uniprotkb:Zfp67(gene name synonym) psi-mi:cyp3a_mouse_dna_5.6(display_short)|psi-mi:EBI-6172014(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zullo et al. (2012) pubmed:22726435|imex:IM-17379 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6172053|imex:IM-17379-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) refseq:NP_033591.2|refseq:XP_006501376.1|refseq:XP_006501377.1|refseq:XP_006501379.1|refseq:XP_006501380.1|refseq:XP_006501381.1|refseq:XP_006501382.1|ensembl:ENSMUSG00000028042(gene)|ensembl:ENSMUST00000029677(transcript)|ensembl:ENSMUST00000107432(transcript)|ensembl:ENSMUST00000107433(transcript)|ensembl:ENSMUST00000107435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001865"(NK T cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007595"(lactation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032868"(response to insulin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:0043370"(regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043376"(regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0043377"(negative regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000640"(positive regulation of SREBP signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000210(BTB/POZ-like)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0051141"(negative regulation of NK T cell proliferation)|interpro:IPR011333(BTB/POZ fold)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q64321 - - - - figure legend:Fig. 5D, 5E|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/07/03 2014/10/16 rogid:sU1MIrKZnvkMEoOdVf75ZNnmwoQ10090 - intact-crc:DD9B1C54CD4971DF false myc tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q64321 uniprotkb:O88895 intact:EBI-642868|uniprotkb:Q80VV5|ensembl:ENSMUSP00000103055|ensembl:ENSMUSP00000103056|ensembl:ENSMUSP00000103058|ensembl:ENSMUSP00000029677 intact:EBI-302263|uniprotkb:O88896 psi-mi:zbt7b_mouse(display_long)|uniprotkb:Zinc finger protein 67(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:Zbtb7b(gene name)|psi-mi:Zbtb7b(display_short)|uniprotkb:Thpok(gene name synonym)|uniprotkb:Zfp67(gene name synonym) psi-mi:hdac3_mouse(display_long)|uniprotkb:Hdac3(gene name)|psi-mi:Hdac3(display_short) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zullo et al. (2012) pubmed:22726435|imex:IM-17379 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6172053|imex:IM-17379-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033591.2|refseq:XP_006501376.1|refseq:XP_006501377.1|refseq:XP_006501379.1|refseq:XP_006501380.1|refseq:XP_006501381.1|refseq:XP_006501382.1|ensembl:ENSMUSG00000028042(gene)|ensembl:ENSMUST00000029677(transcript)|ensembl:ENSMUST00000107432(transcript)|ensembl:ENSMUST00000107433(transcript)|ensembl:ENSMUST00000107435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001865"(NK T cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007595"(lactation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032868"(response to insulin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:0043370"(regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043376"(regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0043377"(negative regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000640"(positive regulation of SREBP signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000210(BTB/POZ-like)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0051141"(negative regulation of NK T cell proliferation)|interpro:IPR011333(BTB/POZ fold)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q64321 go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032692"(negative regulation of interleukin-1 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0051020"(GTPase binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990679"(histone H4-K12 deacetylation)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000726"(negative regulation of cardiac muscle cell differentiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-400206|reactome:R-MMU-9029569|reactome:R-MMU-9707564|dip:DIP-32547N|mint:O88895 - - - figure legend:Fig. 5D, 5E|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/07/03 2014/10/16 rogid:sU1MIrKZnvkMEoOdVf75ZNnmwoQ10090 rogid:0dUkbfmVE49cbSiAPqrb7uFN8l010090 intact-crc:DD9B1C54CD4971DF false myc tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q64321 uniprotkb:O88895 intact:EBI-642868|uniprotkb:Q80VV5|ensembl:ENSMUSP00000103055|ensembl:ENSMUSP00000103056|ensembl:ENSMUSP00000103058|ensembl:ENSMUSP00000029677 intact:EBI-302263|uniprotkb:O88896 psi-mi:zbt7b_mouse(display_long)|uniprotkb:Zinc finger protein 67(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:Zbtb7b(gene name)|psi-mi:Zbtb7b(display_short)|uniprotkb:Thpok(gene name synonym)|uniprotkb:Zfp67(gene name synonym) psi-mi:hdac3_mouse(display_long)|uniprotkb:Hdac3(gene name)|psi-mi:Hdac3(display_short) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zullo et al. (2012) pubmed:22726435|imex:IM-17379 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6172060|imex:IM-17379-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033591.2|refseq:XP_006501376.1|refseq:XP_006501377.1|refseq:XP_006501379.1|refseq:XP_006501380.1|refseq:XP_006501381.1|refseq:XP_006501382.1|ensembl:ENSMUSG00000028042(gene)|ensembl:ENSMUST00000029677(transcript)|ensembl:ENSMUST00000107432(transcript)|ensembl:ENSMUST00000107433(transcript)|ensembl:ENSMUST00000107435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001865"(NK T cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007595"(lactation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032868"(response to insulin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:0043370"(regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043376"(regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0043377"(negative regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000640"(positive regulation of SREBP signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000210(BTB/POZ-like)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0051141"(negative regulation of NK T cell proliferation)|interpro:IPR011333(BTB/POZ fold)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q64321 go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032692"(negative regulation of interleukin-1 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0051020"(GTPase binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990679"(histone H4-K12 deacetylation)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000726"(negative regulation of cardiac muscle cell differentiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-400206|reactome:R-MMU-9029569|reactome:R-MMU-9707564|dip:DIP-32547N|mint:O88895 - - - figure legend:Fig. 5D, 5E|comment:The complexes were supershifted with an anti-Myc antibody and were not formed if the GAGA motif was mutated to CACA|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/07/03 2014/10/16 rogid:sU1MIrKZnvkMEoOdVf75ZNnmwoQ10090 rogid:0dUkbfmVE49cbSiAPqrb7uFN8l010090 intact-crc:BDFEA388E98C4C58 false myc tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q64321 intact:EBI-6172016 intact:EBI-642868|uniprotkb:Q80VV5|ensembl:ENSMUSP00000103055|ensembl:ENSMUSP00000103056|ensembl:ENSMUSP00000103058|ensembl:ENSMUSP00000029677 - psi-mi:zbt7b_mouse(display_long)|uniprotkb:Zinc finger protein 67(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:Zbtb7b(gene name)|psi-mi:Zbtb7b(display_short)|uniprotkb:Thpok(gene name synonym)|uniprotkb:Zfp67(gene name synonym) psi-mi:igh_mouse_dna_1.4(display_short)|psi-mi:EBI-6172016(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zullo et al. (2012) pubmed:22726435|imex:IM-17379 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6172060|imex:IM-17379-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) refseq:NP_033591.2|refseq:XP_006501376.1|refseq:XP_006501377.1|refseq:XP_006501379.1|refseq:XP_006501380.1|refseq:XP_006501381.1|refseq:XP_006501382.1|ensembl:ENSMUSG00000028042(gene)|ensembl:ENSMUST00000029677(transcript)|ensembl:ENSMUST00000107432(transcript)|ensembl:ENSMUST00000107433(transcript)|ensembl:ENSMUST00000107435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001865"(NK T cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007595"(lactation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032868"(response to insulin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:0043370"(regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043376"(regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0043377"(negative regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000640"(positive regulation of SREBP signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000210(BTB/POZ-like)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0051141"(negative regulation of NK T cell proliferation)|interpro:IPR011333(BTB/POZ fold)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q64321 - - - - figure legend:Fig. 5D, 5E|comment:The complexes were supershifted with an anti-Myc antibody and were not formed if the GAGA motif was mutated to CACA|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/07/03 2014/10/16 rogid:sU1MIrKZnvkMEoOdVf75ZNnmwoQ10090 - intact-crc:BDFEA388E98C4C58 false myc tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q64321 intact:EBI-6171956 intact:EBI-642868|uniprotkb:Q80VV5|ensembl:ENSMUSP00000103055|ensembl:ENSMUSP00000103056|ensembl:ENSMUSP00000103058|ensembl:ENSMUSP00000029677 - psi-mi:zbt7b_mouse(display_long)|uniprotkb:Zinc finger protein 67(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:Zbtb7b(gene name)|psi-mi:Zbtb7b(display_short)|uniprotkb:Thpok(gene name synonym)|uniprotkb:Zfp67(gene name synonym) psi-mi:igh_mouse_dna_1.1(display_short)|psi-mi:EBI-6171956(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zullo et al. (2012) pubmed:22726435|imex:IM-17379 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6171997|imex:IM-17379-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) refseq:NP_033591.2|refseq:XP_006501376.1|refseq:XP_006501377.1|refseq:XP_006501379.1|refseq:XP_006501380.1|refseq:XP_006501381.1|refseq:XP_006501382.1|ensembl:ENSMUSG00000028042(gene)|ensembl:ENSMUST00000029677(transcript)|ensembl:ENSMUST00000107432(transcript)|ensembl:ENSMUST00000107433(transcript)|ensembl:ENSMUST00000107435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001865"(NK T cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007595"(lactation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032868"(response to insulin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:0043370"(regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043376"(regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0043377"(negative regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000640"(positive regulation of SREBP signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000210(BTB/POZ-like)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0051141"(negative regulation of NK T cell proliferation)|interpro:IPR011333(BTB/POZ fold)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q64321 - - - - figure legend:Fig. 5D, 5E|comment:The complexes were supershifted with an anti-Myc antibody and were not formed if the GAGA motif was mutated to CACA|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/07/03 2014/10/16 rogid:sU1MIrKZnvkMEoOdVf75ZNnmwoQ10090 - intact-crc:CAB1AA59FF659053 false myc tag:?-? biotin tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q64321 uniprotkb:O88895 intact:EBI-642868|uniprotkb:Q80VV5|ensembl:ENSMUSP00000103055|ensembl:ENSMUSP00000103056|ensembl:ENSMUSP00000103058|ensembl:ENSMUSP00000029677 intact:EBI-302263|uniprotkb:O88896 psi-mi:zbt7b_mouse(display_long)|uniprotkb:Zinc finger protein 67(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:Zbtb7b(gene name)|psi-mi:Zbtb7b(display_short)|uniprotkb:Thpok(gene name synonym)|uniprotkb:Zfp67(gene name synonym) psi-mi:hdac3_mouse(display_long)|uniprotkb:Hdac3(gene name)|psi-mi:Hdac3(display_short) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zullo et al. (2012) pubmed:22726435|imex:IM-17379 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6171997|imex:IM-17379-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033591.2|refseq:XP_006501376.1|refseq:XP_006501377.1|refseq:XP_006501379.1|refseq:XP_006501380.1|refseq:XP_006501381.1|refseq:XP_006501382.1|ensembl:ENSMUSG00000028042(gene)|ensembl:ENSMUST00000029677(transcript)|ensembl:ENSMUST00000107432(transcript)|ensembl:ENSMUST00000107433(transcript)|ensembl:ENSMUST00000107435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001865"(NK T cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007595"(lactation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032868"(response to insulin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:0043370"(regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043376"(regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0043377"(negative regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000640"(positive regulation of SREBP signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000210(BTB/POZ-like)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0051141"(negative regulation of NK T cell proliferation)|interpro:IPR011333(BTB/POZ fold)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q64321 go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032692"(negative regulation of interleukin-1 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0051020"(GTPase binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990679"(histone H4-K12 deacetylation)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000726"(negative regulation of cardiac muscle cell differentiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-400206|reactome:R-MMU-9029569|reactome:R-MMU-9707564|dip:DIP-32547N|mint:O88895 - - - figure legend:Fig. 5D, 5E|comment:The complexes were supershifted with an anti-Myc antibody and were not formed if the GAGA motif was mutated to CACA|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/07/03 2014/10/16 rogid:sU1MIrKZnvkMEoOdVf75ZNnmwoQ10090 rogid:0dUkbfmVE49cbSiAPqrb7uFN8l010090 intact-crc:CAB1AA59FF659053 false myc tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q64321 intact:EBI-6171954 intact:EBI-642868|uniprotkb:Q80VV5|ensembl:ENSMUSP00000103055|ensembl:ENSMUSP00000103056|ensembl:ENSMUSP00000103058|ensembl:ENSMUSP00000029677 - psi-mi:zbt7b_mouse(display_long)|uniprotkb:Zinc finger protein 67(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:Zbtb7b(gene name)|psi-mi:Zbtb7b(display_short)|uniprotkb:Thpok(gene name synonym)|uniprotkb:Zfp67(gene name synonym) psi-mi:cyp3a_mouse_dna_5.1(display_short)|psi-mi:EBI-6171954(display_long) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zullo et al. (2012) pubmed:22726435|imex:IM-17379 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6171994|imex:IM-17379-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0680"(single stranded deoxyribonucleic acid) refseq:NP_033591.2|refseq:XP_006501376.1|refseq:XP_006501377.1|refseq:XP_006501379.1|refseq:XP_006501380.1|refseq:XP_006501381.1|refseq:XP_006501382.1|ensembl:ENSMUSG00000028042(gene)|ensembl:ENSMUST00000029677(transcript)|ensembl:ENSMUST00000107432(transcript)|ensembl:ENSMUST00000107433(transcript)|ensembl:ENSMUST00000107435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001865"(NK T cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007595"(lactation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032868"(response to insulin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:0043370"(regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043376"(regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0043377"(negative regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000640"(positive regulation of SREBP signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000210(BTB/POZ-like)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0051141"(negative regulation of NK T cell proliferation)|interpro:IPR011333(BTB/POZ fold)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q64321 - - - - figure legend:Fig. 5D, 5E|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/07/03 2014/10/16 rogid:sU1MIrKZnvkMEoOdVf75ZNnmwoQ10090 - intact-crc:079AEFB27513F247 false myc tag:?-? biotin tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q64321 uniprotkb:O88895 intact:EBI-642868|uniprotkb:Q80VV5|ensembl:ENSMUSP00000103055|ensembl:ENSMUSP00000103056|ensembl:ENSMUSP00000103058|ensembl:ENSMUSP00000029677 intact:EBI-302263|uniprotkb:O88896 psi-mi:zbt7b_mouse(display_long)|uniprotkb:Zinc finger protein 67(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:Zbtb7b(gene name)|psi-mi:Zbtb7b(display_short)|uniprotkb:Thpok(gene name synonym)|uniprotkb:Zfp67(gene name synonym) psi-mi:hdac3_mouse(display_long)|uniprotkb:Hdac3(gene name)|psi-mi:Hdac3(display_short) psi-mi:"MI:0413"(electrophoretic mobility shift assay) Zullo et al. (2012) pubmed:22726435|imex:IM-17379 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6171994|imex:IM-17379-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033591.2|refseq:XP_006501376.1|refseq:XP_006501377.1|refseq:XP_006501379.1|refseq:XP_006501380.1|refseq:XP_006501381.1|refseq:XP_006501382.1|ensembl:ENSMUSG00000028042(gene)|ensembl:ENSMUST00000029677(transcript)|ensembl:ENSMUST00000107432(transcript)|ensembl:ENSMUST00000107433(transcript)|ensembl:ENSMUST00000107435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001865"(NK T cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007595"(lactation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032868"(response to insulin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:0043370"(regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043376"(regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0043377"(negative regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000640"(positive regulation of SREBP signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000210(BTB/POZ-like)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0051141"(negative regulation of NK T cell proliferation)|interpro:IPR011333(BTB/POZ fold)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q64321 go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032692"(negative regulation of interleukin-1 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0051020"(GTPase binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990679"(histone H4-K12 deacetylation)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000726"(negative regulation of cardiac muscle cell differentiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-MMU-3214815|reactome:R-MMU-350054|reactome:R-MMU-400206|reactome:R-MMU-9029569|reactome:R-MMU-9707564|dip:DIP-32547N|mint:O88895 - - - figure legend:Fig. 5D, 5E|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/07/03 2014/10/16 rogid:sU1MIrKZnvkMEoOdVf75ZNnmwoQ10090 rogid:0dUkbfmVE49cbSiAPqrb7uFN8l010090 intact-crc:079AEFB27513F247 false myc tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)