#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8IN81-1 uniprotkb:P05205 intact:EBI-6171772|ensemblmetazoa:FBpp0083063 intact:EBI-155532|uniprotkb:Q9VLR6|uniprotkb:A4V0F1|uniprotkb:B6UVR4|uniprotkb:B6UVS1|uniprotkb:B6UVS2|uniprotkb:B6UVS3|uniprotkb:B6UVT2|uniprotkb:B6UVT6|uniprotkb:B6UVT7|ensemblmetazoa:FBpp0079251|ensemblmetazoa:FBpp0079252 psi-mi:q8in81-1(display_long)|uniprotkb:E(isoform synonym)|uniprotkb:fru(gene name)|psi-mi:fru(display_short)|uniprotkb:BTB-VI(gene name synonym)|uniprotkb:CG14307(orf name) psi-mi:hp1_drome(display_long)|uniprotkb:"Su(var)205"(gene name)|psi-mi:"Su(var)205"(display_short)|uniprotkb:HP1(gene name synonym)|uniprotkb:CG8409(orf name)|uniprotkb:Non-histone chromosomal protein C1A9 antigen(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ito et al. (2012) imex:IM-17378|pubmed:22682252 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6171780|imex:IM-17378-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-196787(isoform-parent)|ensemblmetazoa:FBgn0004652(gene)|ensemblmetazoa:FBtr0083643(transcript) refseq:NP_476755.1|refseq:NP_723361.1|flybase:FBgn0003607|dip:DIP-21869N|ensemblmetazoa:FBgn0003607(gene)|ensemblmetazoa:FBtr0079635(transcript)|ensemblmetazoa:FBtr0079636(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005701"(polytene chromosome chromocenter)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010369"(chromocenter)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0033697"(obsolete positive regulation of extent of heterochromatin assembly)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1905632"(protein localization to euchromatin)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1905646"(positive regulation of FACT complex assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P05205|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:1Q3L|rcsb pdb:3P7J|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6MHA - - - figure legend:Fig. 3B-D|agonist:Heat-shock|comment:The proportion of Fru-expressing neurons represents less than 2% of all neurons in the brain. To increase the sensitivity of detection, heat-shockable-fruEM was overexpressed in adult flies|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-head)|taxid:7227(Drosophila melanogaster) - 2012/07/02 2014/10/16 rogid:lFLZ7YgoUeb9zUA58E2P1zwFaq07227 rogid:gWEeBI57HBgTrPkRsAgoftkxb+M7227 intact-crc:1D9004C0DA98F4DB|rigid:pvWAm2d1w0y+uTQwM8PcWrBMz+A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IN81-1 uniprotkb:Q94517 intact:EBI-6171772|ensemblmetazoa:FBpp0083063 intact:EBI-302197|uniprotkb:O17429|uniprotkb:O77213|uniprotkb:Q9VZA1|ensemblmetazoa:FBpp0073173 psi-mi:q8in81-1(display_long)|uniprotkb:E(isoform synonym)|uniprotkb:fru(gene name)|psi-mi:fru(display_short)|uniprotkb:BTB-VI(gene name synonym)|uniprotkb:CG14307(orf name) psi-mi:hdac1_drome(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:Rpd3(gene name synonym)|uniprotkb:CG7471(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ito et al. (2012) imex:IM-17378|pubmed:22682252 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6171780|imex:IM-17378-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-196787(isoform-parent)|ensemblmetazoa:FBgn0004652(gene)|ensemblmetazoa:FBtr0083643(transcript) ensemblmetazoa:FBgn0015805(gene)|ensemblmetazoa:FBtr0073317(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048477"(oogenesis)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070983"(dendrite guidance)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0031523"(Myb complex)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q94517|reactome:R-DME-1538133|reactome:R-DME-201722|reactome:R-DME-209394|reactome:R-DME-3214815|reactome:R-DME-3769402|reactome:R-DME-6804758|reactome:R-DME-8943724|reactome:R-DME-983231|refseq:NP_647918.2|flybase:FBgn0015805|dip:DIP-29512N - - - figure legend:Fig. 3B-D|agonist:Heat-shock|comment:The proportion of Fru-expressing neurons represents less than 2% of all neurons in the brain. To increase the sensitivity of detection, heat-shockable-fruEM was overexpressed in adult flies|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-head)|taxid:7227(Drosophila melanogaster) - 2012/07/02 2014/10/16 rogid:lFLZ7YgoUeb9zUA58E2P1zwFaq07227 rogid:HYHCai8wP8lueOr33vYY32w2pHU7227 intact-crc:1D9004C0DA98F4DB|rigid:pvWAm2d1w0y+uTQwM8PcWrBMz+A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IN81-1 uniprotkb:Q9VDK5 intact:EBI-6171772|ensemblmetazoa:FBpp0083063 intact:EBI-3406250|ensemblmetazoa:FBpp0083320 psi-mi:q8in81-1(display_long)|uniprotkb:E(isoform synonym)|uniprotkb:fru(gene name)|psi-mi:fru(display_short)|uniprotkb:BTB-VI(gene name synonym)|uniprotkb:CG14307(orf name) psi-mi:q9vdk5_drome(display_long)|uniprotkb:bon(gene name)|psi-mi:bon(display_short)|uniprotkb:CG15687(gene name synonym)|uniprotkb:CG5206(orf name)|uniprotkb:0241(gene name synonym)|uniprotkb:0249(gene name synonym)|uniprotkb:0434(gene name synonym)|uniprotkb:0487(gene name synonym)|uniprotkb:06(gene name synonym)|uniprotkb:08(gene name synonym)|uniprotkb:12(gene name synonym)|uniprotkb:150268_at(gene name synonym)|uniprotkb:150269_at(gene name synonym)|uniprotkb:20(gene name synonym)|uniprotkb:Bon(gene name synonym)|uniprotkb:Bonus(gene name synonym)|uniprotkb:Dmel\CG5206(gene name synonym)|uniprotkb:anon-WO0118547.418(gene name synonym)|uniprotkb:"l(3)S043420"(gene name synonym)|uniprotkb:Dmel_CG5206(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ito et al. (2012) imex:IM-17378|pubmed:22682252 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6171780|imex:IM-17378-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-196787(isoform-parent)|ensemblmetazoa:FBgn0004652(gene)|ensemblmetazoa:FBtr0083643(transcript) ensemblmetazoa:FBgn0023097(gene)|ensemblmetazoa:FBtr0083912(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|flybase:FBgn0023097|refseq:NP_524724.2 - - - figure legend:Fig. 3B-D|agonist:Heat-shock|comment:The proportion of Fru-expressing neurons represents less than 2% of all neurons in the brain. To increase the sensitivity of detection, heat-shockable-fruEM was overexpressed in adult flies|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-head)|taxid:7227(Drosophila melanogaster) - 2012/07/02 2014/10/16 rogid:lFLZ7YgoUeb9zUA58E2P1zwFaq07227 rogid:Ph5VHrWUFpRMCZQF4iYE7WHxy6M7227 intact-crc:1D9004C0DA98F4DB|rigid:pvWAm2d1w0y+uTQwM8PcWrBMz+A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IN81-6 uniprotkb:P05205 intact:EBI-6171802|ensemblmetazoa:FBpp0083061 intact:EBI-155532|uniprotkb:Q9VLR6|uniprotkb:A4V0F1|uniprotkb:B6UVR4|uniprotkb:B6UVS1|uniprotkb:B6UVS2|uniprotkb:B6UVS3|uniprotkb:B6UVT2|uniprotkb:B6UVT6|uniprotkb:B6UVT7|ensemblmetazoa:FBpp0079251|ensemblmetazoa:FBpp0079252 psi-mi:q8in81-6(display_long)|uniprotkb:B(isoform synonym)|uniprotkb:fru(gene name)|psi-mi:fru(display_short)|uniprotkb:BTB-VI(gene name synonym)|uniprotkb:CG14307(orf name) psi-mi:hp1_drome(display_long)|uniprotkb:"Su(var)205"(gene name)|psi-mi:"Su(var)205"(display_short)|uniprotkb:HP1(gene name synonym)|uniprotkb:CG8409(orf name)|uniprotkb:Non-histone chromosomal protein C1A9 antigen(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ito et al. (2012) imex:IM-17378|pubmed:22682252 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6171811|imex:IM-17378-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-196787(isoform-parent)|ensemblmetazoa:FBgn0004652(gene)|ensemblmetazoa:FBtr0083641(transcript) refseq:NP_476755.1|refseq:NP_723361.1|flybase:FBgn0003607|dip:DIP-21869N|ensemblmetazoa:FBgn0003607(gene)|ensemblmetazoa:FBtr0079635(transcript)|ensemblmetazoa:FBtr0079636(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005701"(polytene chromosome chromocenter)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010369"(chromocenter)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0033697"(obsolete positive regulation of extent of heterochromatin assembly)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1905632"(protein localization to euchromatin)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1905646"(positive regulation of FACT complex assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P05205|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:1Q3L|rcsb pdb:3P7J|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6MHA - - - figure legend:Fig. 3G, 3H|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2012/07/02 2014/10/16 rogid:5U2fauaZ7sM8Pa8XSYQn86+XZw87227 rogid:gWEeBI57HBgTrPkRsAgoftkxb+M7227 intact-crc:DC35ACC01B489381|rigid:K52EOQy02tMQZwQR1eVf/CF7etE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IN81-6 uniprotkb:Q9VDK5 intact:EBI-6171802|ensemblmetazoa:FBpp0083061 intact:EBI-3406250|ensemblmetazoa:FBpp0083320 psi-mi:q8in81-6(display_long)|uniprotkb:B(isoform synonym)|uniprotkb:fru(gene name)|psi-mi:fru(display_short)|uniprotkb:BTB-VI(gene name synonym)|uniprotkb:CG14307(orf name) psi-mi:q9vdk5_drome(display_long)|uniprotkb:bon(gene name)|psi-mi:bon(display_short)|uniprotkb:CG15687(gene name synonym)|uniprotkb:CG5206(orf name)|uniprotkb:0241(gene name synonym)|uniprotkb:0249(gene name synonym)|uniprotkb:0434(gene name synonym)|uniprotkb:0487(gene name synonym)|uniprotkb:06(gene name synonym)|uniprotkb:08(gene name synonym)|uniprotkb:12(gene name synonym)|uniprotkb:150268_at(gene name synonym)|uniprotkb:150269_at(gene name synonym)|uniprotkb:20(gene name synonym)|uniprotkb:Bon(gene name synonym)|uniprotkb:Bonus(gene name synonym)|uniprotkb:Dmel\CG5206(gene name synonym)|uniprotkb:anon-WO0118547.418(gene name synonym)|uniprotkb:"l(3)S043420"(gene name synonym)|uniprotkb:Dmel_CG5206(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ito et al. (2012) imex:IM-17378|pubmed:22682252 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6171811|imex:IM-17378-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-196787(isoform-parent)|ensemblmetazoa:FBgn0004652(gene)|ensemblmetazoa:FBtr0083641(transcript) ensemblmetazoa:FBgn0023097(gene)|ensemblmetazoa:FBtr0083912(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|flybase:FBgn0023097|refseq:NP_524724.2 - - - figure legend:Fig. 3G, 3H|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2012/07/02 2014/10/16 rogid:5U2fauaZ7sM8Pa8XSYQn86+XZw87227 rogid:Ph5VHrWUFpRMCZQF4iYE7WHxy6M7227 intact-crc:DC35ACC01B489381|rigid:K52EOQy02tMQZwQR1eVf/CF7etE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IN81-6 uniprotkb:Q94517 intact:EBI-6171802|ensemblmetazoa:FBpp0083061 intact:EBI-302197|uniprotkb:O17429|uniprotkb:O77213|uniprotkb:Q9VZA1|ensemblmetazoa:FBpp0073173 psi-mi:q8in81-6(display_long)|uniprotkb:B(isoform synonym)|uniprotkb:fru(gene name)|psi-mi:fru(display_short)|uniprotkb:BTB-VI(gene name synonym)|uniprotkb:CG14307(orf name) psi-mi:hdac1_drome(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:Rpd3(gene name synonym)|uniprotkb:CG7471(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ito et al. (2012) imex:IM-17378|pubmed:22682252 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6171811|imex:IM-17378-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-196787(isoform-parent)|ensemblmetazoa:FBgn0004652(gene)|ensemblmetazoa:FBtr0083641(transcript) ensemblmetazoa:FBgn0015805(gene)|ensemblmetazoa:FBtr0073317(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048477"(oogenesis)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070983"(dendrite guidance)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0031523"(Myb complex)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q94517|reactome:R-DME-1538133|reactome:R-DME-201722|reactome:R-DME-209394|reactome:R-DME-3214815|reactome:R-DME-3769402|reactome:R-DME-6804758|reactome:R-DME-8943724|reactome:R-DME-983231|refseq:NP_647918.2|flybase:FBgn0015805|dip:DIP-29512N - - - figure legend:Fig. 3G, 3H|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2012/07/02 2014/10/16 rogid:5U2fauaZ7sM8Pa8XSYQn86+XZw87227 rogid:HYHCai8wP8lueOr33vYY32w2pHU7227 intact-crc:DC35ACC01B489381|rigid:K52EOQy02tMQZwQR1eVf/CF7etE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IN81-6 uniprotkb:Q9VDK5 intact:EBI-6171802|ensemblmetazoa:FBpp0083061 intact:EBI-3406250|ensemblmetazoa:FBpp0083320 psi-mi:q8in81-6(display_long)|uniprotkb:B(isoform synonym)|uniprotkb:fru(gene name)|psi-mi:fru(display_short)|uniprotkb:BTB-VI(gene name synonym)|uniprotkb:CG14307(orf name) psi-mi:q9vdk5_drome(display_long)|uniprotkb:bon(gene name)|psi-mi:bon(display_short)|uniprotkb:CG15687(gene name synonym)|uniprotkb:CG5206(orf name)|uniprotkb:0241(gene name synonym)|uniprotkb:0249(gene name synonym)|uniprotkb:0434(gene name synonym)|uniprotkb:0487(gene name synonym)|uniprotkb:06(gene name synonym)|uniprotkb:08(gene name synonym)|uniprotkb:12(gene name synonym)|uniprotkb:150268_at(gene name synonym)|uniprotkb:150269_at(gene name synonym)|uniprotkb:20(gene name synonym)|uniprotkb:Bon(gene name synonym)|uniprotkb:Bonus(gene name synonym)|uniprotkb:Dmel\CG5206(gene name synonym)|uniprotkb:anon-WO0118547.418(gene name synonym)|uniprotkb:"l(3)S043420"(gene name synonym)|uniprotkb:Dmel_CG5206(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ito et al. (2012) imex:IM-17378|pubmed:22682252 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6171827|imex:IM-17378-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-196787(isoform-parent)|ensemblmetazoa:FBgn0004652(gene)|ensemblmetazoa:FBtr0083641(transcript) ensemblmetazoa:FBgn0023097(gene)|ensemblmetazoa:FBtr0083912(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|flybase:FBgn0023097|refseq:NP_524724.2 - - - figure legend:Fig. 3I|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2012/07/02 2014/10/16 rogid:5U2fauaZ7sM8Pa8XSYQn86+XZw87227 rogid:Ph5VHrWUFpRMCZQF4iYE7WHxy6M7227 intact-crc:78A516B7269EDFDC|rigid:nutVzcEqc4zKyr0AtdPJaC0LWvQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IN81-6 uniprotkb:P05205 intact:EBI-6171802|ensemblmetazoa:FBpp0083061 intact:EBI-155532|uniprotkb:Q9VLR6|uniprotkb:A4V0F1|uniprotkb:B6UVR4|uniprotkb:B6UVS1|uniprotkb:B6UVS2|uniprotkb:B6UVS3|uniprotkb:B6UVT2|uniprotkb:B6UVT6|uniprotkb:B6UVT7|ensemblmetazoa:FBpp0079251|ensemblmetazoa:FBpp0079252 psi-mi:q8in81-6(display_long)|uniprotkb:B(isoform synonym)|uniprotkb:fru(gene name)|psi-mi:fru(display_short)|uniprotkb:BTB-VI(gene name synonym)|uniprotkb:CG14307(orf name) psi-mi:hp1_drome(display_long)|uniprotkb:"Su(var)205"(gene name)|psi-mi:"Su(var)205"(display_short)|uniprotkb:HP1(gene name synonym)|uniprotkb:CG8409(orf name)|uniprotkb:Non-histone chromosomal protein C1A9 antigen(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ito et al. (2012) imex:IM-17378|pubmed:22682252 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6171827|imex:IM-17378-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-196787(isoform-parent)|ensemblmetazoa:FBgn0004652(gene)|ensemblmetazoa:FBtr0083641(transcript) refseq:NP_476755.1|refseq:NP_723361.1|flybase:FBgn0003607|dip:DIP-21869N|ensemblmetazoa:FBgn0003607(gene)|ensemblmetazoa:FBtr0079635(transcript)|ensemblmetazoa:FBtr0079636(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005701"(polytene chromosome chromocenter)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010369"(chromocenter)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0033697"(obsolete positive regulation of extent of heterochromatin assembly)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1905632"(protein localization to euchromatin)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1905646"(positive regulation of FACT complex assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P05205|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:1Q3L|rcsb pdb:3P7J|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6MHA - - - figure legend:Fig. 3I|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2012/07/02 2014/10/16 rogid:5U2fauaZ7sM8Pa8XSYQn86+XZw87227 rogid:gWEeBI57HBgTrPkRsAgoftkxb+M7227 intact-crc:78A516B7269EDFDC|rigid:nutVzcEqc4zKyr0AtdPJaC0LWvQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IN81-6 uniprotkb:P05205 intact:EBI-6171802|ensemblmetazoa:FBpp0083061 intact:EBI-155532|uniprotkb:Q9VLR6|uniprotkb:A4V0F1|uniprotkb:B6UVR4|uniprotkb:B6UVS1|uniprotkb:B6UVS2|uniprotkb:B6UVS3|uniprotkb:B6UVT2|uniprotkb:B6UVT6|uniprotkb:B6UVT7|ensemblmetazoa:FBpp0079251|ensemblmetazoa:FBpp0079252 psi-mi:q8in81-6(display_long)|uniprotkb:B(isoform synonym)|uniprotkb:fru(gene name)|psi-mi:fru(display_short)|uniprotkb:BTB-VI(gene name synonym)|uniprotkb:CG14307(orf name) psi-mi:hp1_drome(display_long)|uniprotkb:"Su(var)205"(gene name)|psi-mi:"Su(var)205"(display_short)|uniprotkb:HP1(gene name synonym)|uniprotkb:CG8409(orf name)|uniprotkb:Non-histone chromosomal protein C1A9 antigen(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ito et al. (2012) imex:IM-17378|pubmed:22682252 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6171819|imex:IM-17378-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-196787(isoform-parent)|ensemblmetazoa:FBgn0004652(gene)|ensemblmetazoa:FBtr0083641(transcript) refseq:NP_476755.1|refseq:NP_723361.1|flybase:FBgn0003607|dip:DIP-21869N|ensemblmetazoa:FBgn0003607(gene)|ensemblmetazoa:FBtr0079635(transcript)|ensemblmetazoa:FBtr0079636(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005701"(polytene chromosome chromocenter)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010369"(chromocenter)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0033697"(obsolete positive regulation of extent of heterochromatin assembly)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1905632"(protein localization to euchromatin)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1905646"(positive regulation of FACT complex assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P05205|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:1Q3L|rcsb pdb:3P7J|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6MHA - - - figure legend:Fig. 3I|agonist:Heat-shock|comment:bon also present but not shown to be required for the interaction|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2012/07/02 2014/10/16 rogid:5U2fauaZ7sM8Pa8XSYQn86+XZw87227 rogid:gWEeBI57HBgTrPkRsAgoftkxb+M7227 intact-crc:7535886FF9181FD1|rigid:1hvTcBbFHFRxmxa0YnIX7+wFVeA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IN81-6 uniprotkb:Q94517 intact:EBI-6171802|ensemblmetazoa:FBpp0083061 intact:EBI-302197|uniprotkb:O17429|uniprotkb:O77213|uniprotkb:Q9VZA1|ensemblmetazoa:FBpp0073173 psi-mi:q8in81-6(display_long)|uniprotkb:B(isoform synonym)|uniprotkb:fru(gene name)|psi-mi:fru(display_short)|uniprotkb:BTB-VI(gene name synonym)|uniprotkb:CG14307(orf name) psi-mi:hdac1_drome(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:Rpd3(gene name synonym)|uniprotkb:CG7471(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ito et al. (2012) imex:IM-17378|pubmed:22682252 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6171819|imex:IM-17378-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0941"(competitor) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-196787(isoform-parent)|ensemblmetazoa:FBgn0004652(gene)|ensemblmetazoa:FBtr0083641(transcript) ensemblmetazoa:FBgn0015805(gene)|ensemblmetazoa:FBtr0073317(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048477"(oogenesis)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070983"(dendrite guidance)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0031523"(Myb complex)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q94517|reactome:R-DME-1538133|reactome:R-DME-201722|reactome:R-DME-209394|reactome:R-DME-3214815|reactome:R-DME-3769402|reactome:R-DME-6804758|reactome:R-DME-8943724|reactome:R-DME-983231|refseq:NP_647918.2|flybase:FBgn0015805|dip:DIP-29512N - - - figure legend:Fig. 3I|agonist:Heat-shock|comment:bon also present but not shown to be required for the interaction|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2012/07/02 2014/10/16 rogid:5U2fauaZ7sM8Pa8XSYQn86+XZw87227 rogid:HYHCai8wP8lueOr33vYY32w2pHU7227 intact-crc:7535886FF9181FD1|rigid:1hvTcBbFHFRxmxa0YnIX7+wFVeA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IN81-6 uniprotkb:Q9VDK5 intact:EBI-6171802|ensemblmetazoa:FBpp0083061 intact:EBI-3406250|ensemblmetazoa:FBpp0083320 psi-mi:q8in81-6(display_long)|uniprotkb:B(isoform synonym)|uniprotkb:fru(gene name)|psi-mi:fru(display_short)|uniprotkb:BTB-VI(gene name synonym)|uniprotkb:CG14307(orf name) psi-mi:q9vdk5_drome(display_long)|uniprotkb:bon(gene name)|psi-mi:bon(display_short)|uniprotkb:CG15687(gene name synonym)|uniprotkb:CG5206(orf name)|uniprotkb:0241(gene name synonym)|uniprotkb:0249(gene name synonym)|uniprotkb:0434(gene name synonym)|uniprotkb:0487(gene name synonym)|uniprotkb:06(gene name synonym)|uniprotkb:08(gene name synonym)|uniprotkb:12(gene name synonym)|uniprotkb:150268_at(gene name synonym)|uniprotkb:150269_at(gene name synonym)|uniprotkb:20(gene name synonym)|uniprotkb:Bon(gene name synonym)|uniprotkb:Bonus(gene name synonym)|uniprotkb:Dmel\CG5206(gene name synonym)|uniprotkb:anon-WO0118547.418(gene name synonym)|uniprotkb:"l(3)S043420"(gene name synonym)|uniprotkb:Dmel_CG5206(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ito et al. (2012) imex:IM-17378|pubmed:22682252 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6171794|imex:IM-17378-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-196787(isoform-parent)|ensemblmetazoa:FBgn0004652(gene)|ensemblmetazoa:FBtr0083641(transcript) ensemblmetazoa:FBgn0023097(gene)|ensemblmetazoa:FBtr0083912(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|flybase:FBgn0023097|refseq:NP_524724.2 - - - figure legend:Fig. 3F|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2012/07/02 2014/10/16 rogid:5U2fauaZ7sM8Pa8XSYQn86+XZw87227 rogid:Ph5VHrWUFpRMCZQF4iYE7WHxy6M7227 intact-crc:08AC98E969D96FC0|rigid:K52EOQy02tMQZwQR1eVf/CF7etE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IN81-6 uniprotkb:Q94517 intact:EBI-6171802|ensemblmetazoa:FBpp0083061 intact:EBI-302197|uniprotkb:O17429|uniprotkb:O77213|uniprotkb:Q9VZA1|ensemblmetazoa:FBpp0073173 psi-mi:q8in81-6(display_long)|uniprotkb:B(isoform synonym)|uniprotkb:fru(gene name)|psi-mi:fru(display_short)|uniprotkb:BTB-VI(gene name synonym)|uniprotkb:CG14307(orf name) psi-mi:hdac1_drome(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:Rpd3(gene name synonym)|uniprotkb:CG7471(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ito et al. (2012) imex:IM-17378|pubmed:22682252 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6171794|imex:IM-17378-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-196787(isoform-parent)|ensemblmetazoa:FBgn0004652(gene)|ensemblmetazoa:FBtr0083641(transcript) ensemblmetazoa:FBgn0015805(gene)|ensemblmetazoa:FBtr0073317(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048477"(oogenesis)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070983"(dendrite guidance)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0031523"(Myb complex)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q94517|reactome:R-DME-1538133|reactome:R-DME-201722|reactome:R-DME-209394|reactome:R-DME-3214815|reactome:R-DME-3769402|reactome:R-DME-6804758|reactome:R-DME-8943724|reactome:R-DME-983231|refseq:NP_647918.2|flybase:FBgn0015805|dip:DIP-29512N - - - figure legend:Fig. 3F|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2012/07/02 2014/10/16 rogid:5U2fauaZ7sM8Pa8XSYQn86+XZw87227 rogid:HYHCai8wP8lueOr33vYY32w2pHU7227 intact-crc:08AC98E969D96FC0|rigid:K52EOQy02tMQZwQR1eVf/CF7etE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IN81-6 uniprotkb:P05205 intact:EBI-6171802|ensemblmetazoa:FBpp0083061 intact:EBI-155532|uniprotkb:Q9VLR6|uniprotkb:A4V0F1|uniprotkb:B6UVR4|uniprotkb:B6UVS1|uniprotkb:B6UVS2|uniprotkb:B6UVS3|uniprotkb:B6UVT2|uniprotkb:B6UVT6|uniprotkb:B6UVT7|ensemblmetazoa:FBpp0079251|ensemblmetazoa:FBpp0079252 psi-mi:q8in81-6(display_long)|uniprotkb:B(isoform synonym)|uniprotkb:fru(gene name)|psi-mi:fru(display_short)|uniprotkb:BTB-VI(gene name synonym)|uniprotkb:CG14307(orf name) psi-mi:hp1_drome(display_long)|uniprotkb:"Su(var)205"(gene name)|psi-mi:"Su(var)205"(display_short)|uniprotkb:HP1(gene name synonym)|uniprotkb:CG8409(orf name)|uniprotkb:Non-histone chromosomal protein C1A9 antigen(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ito et al. (2012) imex:IM-17378|pubmed:22682252 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6171794|imex:IM-17378-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-196787(isoform-parent)|ensemblmetazoa:FBgn0004652(gene)|ensemblmetazoa:FBtr0083641(transcript) refseq:NP_476755.1|refseq:NP_723361.1|flybase:FBgn0003607|dip:DIP-21869N|ensemblmetazoa:FBgn0003607(gene)|ensemblmetazoa:FBtr0079635(transcript)|ensemblmetazoa:FBtr0079636(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005701"(polytene chromosome chromocenter)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010369"(chromocenter)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0033697"(obsolete positive regulation of extent of heterochromatin assembly)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1905632"(protein localization to euchromatin)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1905646"(positive regulation of FACT complex assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P05205|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:1Q3L|rcsb pdb:3P7J|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6MHA - - - figure legend:Fig. 3F|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2012/07/02 2014/10/16 rogid:5U2fauaZ7sM8Pa8XSYQn86+XZw87227 rogid:gWEeBI57HBgTrPkRsAgoftkxb+M7227 intact-crc:08AC98E969D96FC0|rigid:K52EOQy02tMQZwQR1eVf/CF7etE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VDK5 uniprotkb:Q8IN81-6 intact:EBI-3406250|ensemblmetazoa:FBpp0083320 intact:EBI-6171802|ensemblmetazoa:FBpp0083061 psi-mi:q9vdk5_drome(display_long)|uniprotkb:bon(gene name)|psi-mi:bon(display_short)|uniprotkb:CG15687(gene name synonym)|uniprotkb:CG5206(orf name)|uniprotkb:0241(gene name synonym)|uniprotkb:0249(gene name synonym)|uniprotkb:0434(gene name synonym)|uniprotkb:0487(gene name synonym)|uniprotkb:06(gene name synonym)|uniprotkb:08(gene name synonym)|uniprotkb:12(gene name synonym)|uniprotkb:150268_at(gene name synonym)|uniprotkb:150269_at(gene name synonym)|uniprotkb:20(gene name synonym)|uniprotkb:Bon(gene name synonym)|uniprotkb:Bonus(gene name synonym)|uniprotkb:Dmel\CG5206(gene name synonym)|uniprotkb:anon-WO0118547.418(gene name synonym)|uniprotkb:"l(3)S043420"(gene name synonym)|uniprotkb:Dmel_CG5206(orf name) psi-mi:q8in81-6(display_long)|uniprotkb:B(isoform synonym)|uniprotkb:fru(gene name)|psi-mi:fru(display_short)|uniprotkb:BTB-VI(gene name synonym)|uniprotkb:CG14307(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ito et al. (2012) imex:IM-17378|pubmed:22682252 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6171860|imex:IM-17378-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0023097(gene)|ensemblmetazoa:FBtr0083912(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|flybase:FBgn0023097|refseq:NP_524724.2 intact:EBI-196787(isoform-parent)|ensemblmetazoa:FBgn0004652(gene)|ensemblmetazoa:FBtr0083641(transcript) - - - figure legend:Supp. Fig. 2B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2012/07/02 2014/10/16 rogid:Ph5VHrWUFpRMCZQF4iYE7WHxy6M7227 rogid:5U2fauaZ7sM8Pa8XSYQn86+XZw87227 intact-crc:B0E66BEC5682DA8D|rigid:tO4VeBCkqvDUSE0yqrm3tWLsMz4 false myc tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VDK5 uniprotkb:Q8IN81-9 intact:EBI-3406250|ensemblmetazoa:FBpp0083320 intact:EBI-6171848|ensemblmetazoa:FBpp0083066 psi-mi:q9vdk5_drome(display_long)|uniprotkb:bon(gene name)|psi-mi:bon(display_short)|uniprotkb:CG15687(gene name synonym)|uniprotkb:CG5206(orf name)|uniprotkb:0241(gene name synonym)|uniprotkb:0249(gene name synonym)|uniprotkb:0434(gene name synonym)|uniprotkb:0487(gene name synonym)|uniprotkb:06(gene name synonym)|uniprotkb:08(gene name synonym)|uniprotkb:12(gene name synonym)|uniprotkb:150268_at(gene name synonym)|uniprotkb:150269_at(gene name synonym)|uniprotkb:20(gene name synonym)|uniprotkb:Bon(gene name synonym)|uniprotkb:Bonus(gene name synonym)|uniprotkb:Dmel\CG5206(gene name synonym)|uniprotkb:anon-WO0118547.418(gene name synonym)|uniprotkb:"l(3)S043420"(gene name synonym)|uniprotkb:Dmel_CG5206(orf name) psi-mi:q8in81-9(display_long)|uniprotkb:A(isoform synonym)|uniprotkb:fru(gene name)|psi-mi:fru(display_short)|uniprotkb:BTB-VI(gene name synonym)|uniprotkb:CG14307(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ito et al. (2012) imex:IM-17378|pubmed:22682252 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6171846|imex:IM-17378-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0023097(gene)|ensemblmetazoa:FBtr0083912(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|flybase:FBgn0023097|refseq:NP_524724.2 intact:EBI-196787(isoform-parent)|ensemblmetazoa:FBgn0004652(gene)|ensemblmetazoa:FBtr0083646(transcript) - - - figure legend:Supp. Fig. 2B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2012/07/02 2014/10/16 rogid:Ph5VHrWUFpRMCZQF4iYE7WHxy6M7227 rogid:PEgPVbYATwnUD5rcVKE7lyksTzg7227 intact-crc:BD1FB0858AB12941|rigid:4kdvb2jiC2TH/JthM3pbTbPQKhY false myc tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VDK5 uniprotkb:Q8IN81-1 intact:EBI-3406250|ensemblmetazoa:FBpp0083320 intact:EBI-6171772|ensemblmetazoa:FBpp0083063 psi-mi:q9vdk5_drome(display_long)|uniprotkb:bon(gene name)|psi-mi:bon(display_short)|uniprotkb:CG15687(gene name synonym)|uniprotkb:CG5206(orf name)|uniprotkb:0241(gene name synonym)|uniprotkb:0249(gene name synonym)|uniprotkb:0434(gene name synonym)|uniprotkb:0487(gene name synonym)|uniprotkb:06(gene name synonym)|uniprotkb:08(gene name synonym)|uniprotkb:12(gene name synonym)|uniprotkb:150268_at(gene name synonym)|uniprotkb:150269_at(gene name synonym)|uniprotkb:20(gene name synonym)|uniprotkb:Bon(gene name synonym)|uniprotkb:Bonus(gene name synonym)|uniprotkb:Dmel\CG5206(gene name synonym)|uniprotkb:anon-WO0118547.418(gene name synonym)|uniprotkb:"l(3)S043420"(gene name synonym)|uniprotkb:Dmel_CG5206(orf name) psi-mi:q8in81-1(display_long)|uniprotkb:E(isoform synonym)|uniprotkb:fru(gene name)|psi-mi:fru(display_short)|uniprotkb:BTB-VI(gene name synonym)|uniprotkb:CG14307(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ito et al. (2012) imex:IM-17378|pubmed:22682252 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6171840|imex:IM-17378-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0023097(gene)|ensemblmetazoa:FBtr0083912(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|flybase:FBgn0023097|refseq:NP_524724.2 intact:EBI-196787(isoform-parent)|ensemblmetazoa:FBgn0004652(gene)|ensemblmetazoa:FBtr0083643(transcript) - - - figure legend:Supp. Fig. 2B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2012/07/02 2014/10/16 rogid:Ph5VHrWUFpRMCZQF4iYE7WHxy6M7227 rogid:lFLZ7YgoUeb9zUA58E2P1zwFaq07227 intact-crc:B6A16BEE003301E1|rigid:C8Oo0kNCyeBHdjCMKOsiGS8iOxw false myc tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P05205 uniprotkb:Q9VDK5 intact:EBI-155532|uniprotkb:Q9VLR6|uniprotkb:A4V0F1|uniprotkb:B6UVR4|uniprotkb:B6UVS1|uniprotkb:B6UVS2|uniprotkb:B6UVS3|uniprotkb:B6UVT2|uniprotkb:B6UVT6|uniprotkb:B6UVT7|ensemblmetazoa:FBpp0079251|ensemblmetazoa:FBpp0079252 intact:EBI-3406250|ensemblmetazoa:FBpp0083320 psi-mi:hp1_drome(display_long)|uniprotkb:"Su(var)205"(gene name)|psi-mi:"Su(var)205"(display_short)|uniprotkb:HP1(gene name synonym)|uniprotkb:CG8409(orf name)|uniprotkb:Non-histone chromosomal protein C1A9 antigen(gene name synonym) psi-mi:q9vdk5_drome(display_long)|uniprotkb:bon(gene name)|psi-mi:bon(display_short)|uniprotkb:CG15687(gene name synonym)|uniprotkb:CG5206(orf name)|uniprotkb:0241(gene name synonym)|uniprotkb:0249(gene name synonym)|uniprotkb:0434(gene name synonym)|uniprotkb:0487(gene name synonym)|uniprotkb:06(gene name synonym)|uniprotkb:08(gene name synonym)|uniprotkb:12(gene name synonym)|uniprotkb:150268_at(gene name synonym)|uniprotkb:150269_at(gene name synonym)|uniprotkb:20(gene name synonym)|uniprotkb:Bon(gene name synonym)|uniprotkb:Bonus(gene name synonym)|uniprotkb:Dmel\CG5206(gene name synonym)|uniprotkb:anon-WO0118547.418(gene name synonym)|uniprotkb:"l(3)S043420"(gene name synonym)|uniprotkb:Dmel_CG5206(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ito et al. (2012) imex:IM-17378|pubmed:22682252 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6171897|imex:IM-17378-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_476755.1|refseq:NP_723361.1|flybase:FBgn0003607|dip:DIP-21869N|ensemblmetazoa:FBgn0003607(gene)|ensemblmetazoa:FBtr0079635(transcript)|ensemblmetazoa:FBtr0079636(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005701"(polytene chromosome chromocenter)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010369"(chromocenter)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0033697"(obsolete positive regulation of extent of heterochromatin assembly)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1905632"(protein localization to euchromatin)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1905646"(positive regulation of FACT complex assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P05205|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:1Q3L|rcsb pdb:3P7J|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6MHA ensemblmetazoa:FBgn0023097(gene)|ensemblmetazoa:FBtr0083912(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|flybase:FBgn0023097|refseq:NP_524724.2 - - - figure legend:Supp. Fig. 2D|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells) - 2012/07/02 2014/10/16 rogid:gWEeBI57HBgTrPkRsAgoftkxb+M7227 rogid:Ph5VHrWUFpRMCZQF4iYE7WHxy6M7227 intact-crc:88FD958BD78887E3|rigid:Tte/S7qavzMLya7gTkqeeEkYl1E false myc tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q94517 uniprotkb:Q9VDK5 intact:EBI-302197|uniprotkb:O17429|uniprotkb:O77213|uniprotkb:Q9VZA1|ensemblmetazoa:FBpp0073173 intact:EBI-3406250|ensemblmetazoa:FBpp0083320 psi-mi:hdac1_drome(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:Rpd3(gene name synonym)|uniprotkb:CG7471(orf name) psi-mi:q9vdk5_drome(display_long)|uniprotkb:bon(gene name)|psi-mi:bon(display_short)|uniprotkb:CG15687(gene name synonym)|uniprotkb:CG5206(orf name)|uniprotkb:0241(gene name synonym)|uniprotkb:0249(gene name synonym)|uniprotkb:0434(gene name synonym)|uniprotkb:0487(gene name synonym)|uniprotkb:06(gene name synonym)|uniprotkb:08(gene name synonym)|uniprotkb:12(gene name synonym)|uniprotkb:150268_at(gene name synonym)|uniprotkb:150269_at(gene name synonym)|uniprotkb:20(gene name synonym)|uniprotkb:Bon(gene name synonym)|uniprotkb:Bonus(gene name synonym)|uniprotkb:Dmel\CG5206(gene name synonym)|uniprotkb:anon-WO0118547.418(gene name synonym)|uniprotkb:"l(3)S043420"(gene name synonym)|uniprotkb:Dmel_CG5206(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ito et al. (2012) imex:IM-17378|pubmed:22682252 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6171872|imex:IM-17378-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0015805(gene)|ensemblmetazoa:FBtr0073317(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048477"(oogenesis)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070983"(dendrite guidance)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0031523"(Myb complex)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q94517|reactome:R-DME-1538133|reactome:R-DME-201722|reactome:R-DME-209394|reactome:R-DME-3214815|reactome:R-DME-3769402|reactome:R-DME-6804758|reactome:R-DME-8943724|reactome:R-DME-983231|refseq:NP_647918.2|flybase:FBgn0015805|dip:DIP-29512N ensemblmetazoa:FBgn0023097(gene)|ensemblmetazoa:FBtr0083912(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|flybase:FBgn0023097|refseq:NP_524724.2 - - - figure legend:Supp. Fig. 2C|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-larva)|taxid:7227(Drosophila melanogaster larva) - 2012/07/02 2014/10/16 rogid:HYHCai8wP8lueOr33vYY32w2pHU7227 rogid:Ph5VHrWUFpRMCZQF4iYE7WHxy6M7227 intact-crc:C60975B3140A2E67|rigid:6rIdXsIE+ercxx3tpUdjjfxCWMQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IN81 uniprotkb:P05205 intact:EBI-196787|uniprotkb:O44708|uniprotkb:P91618|uniprotkb:P91619|uniprotkb:Q24004|uniprotkb:Q8IN80|uniprotkb:Q8IN82|uniprotkb:Q8IN83|uniprotkb:Q9GU18|uniprotkb:Q9GU19|uniprotkb:Q9GU20|uniprotkb:Q9GU21|uniprotkb:Q9GU22|uniprotkb:Q9VE64|uniprotkb:Q9VE65|uniprotkb:Q9VE66|uniprotkb:Q9VE67|intact:EBI-3407284|uniprotkb:A4V334|uniprotkb:Q29QE0|uniprotkb:Q7KSD2|uniprotkb:Q7KSD5|uniprotkb:Q7KSD6|uniprotkb:Q8IS35|uniprotkb:Q8IS36|intact:EBI-9944780|ensemblmetazoa:FBpp0083063 intact:EBI-155532|uniprotkb:Q9VLR6|uniprotkb:A4V0F1|uniprotkb:B6UVR4|uniprotkb:B6UVS1|uniprotkb:B6UVS2|uniprotkb:B6UVS3|uniprotkb:B6UVT2|uniprotkb:B6UVT6|uniprotkb:B6UVT7|ensemblmetazoa:FBpp0079251|ensemblmetazoa:FBpp0079252 psi-mi:fru_drome(display_long)|uniprotkb:fru(gene name)|psi-mi:fru(display_short)|uniprotkb:BTB-VI(gene name synonym)|uniprotkb:CG14307(orf name) psi-mi:hp1_drome(display_long)|uniprotkb:"Su(var)205"(gene name)|psi-mi:"Su(var)205"(display_short)|uniprotkb:HP1(gene name synonym)|uniprotkb:CG8409(orf name)|uniprotkb:Non-histone chromosomal protein C1A9 antigen(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Ito et al. (2012) imex:IM-17378|pubmed:22682252 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-6248533|imex:IM-17378-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163648.1|refseq:NP_524397.2|refseq:NP_732344.1|refseq:NP_732345.1|refseq:NP_732346.1|refseq:NP_732347.1|refseq:NP_732348.1|refseq:NP_732349.1|refseq:NP_732350.1|refseq:NP_996234.1|refseq:NP_996235.1|refseq:NP_996236.1|refseq:NP_996237.1|refseq:NP_996238.1|flybase:FBgn0004652|dip:DIP-17120N|ensemblmetazoa:FBgn0004652(gene)|ensemblmetazoa:FBtr0083643(transcript)|go:"GO:0002118"(aggressive behavior)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007530"(sex determination)|go:"GO:0007617"(mating behavior)|go:"GO:0007620"(copulation)|go:"GO:0008049"(male courtship behavior)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0016543"(male courtship behavior, orientation prior to leg tapping and wing vibration)|go:"GO:0016544"(male courtship behavior, tapping to detect pheromone)|go:"GO:0016545"(male courtship behavior, veined wing vibration)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0045433"(male courtship behavior, veined wing generated song production)|go:"GO:0046661"(male sex differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048047"(mating behavior, sex discrimination)|go:"GO:0048065"(male courtship behavior, veined wing extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060179"(male mating behavior)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 refseq:NP_476755.1|refseq:NP_723361.1|flybase:FBgn0003607|dip:DIP-21869N|ensemblmetazoa:FBgn0003607(gene)|ensemblmetazoa:FBtr0079635(transcript)|ensemblmetazoa:FBtr0079636(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005700"(polytene chromosome)|go:"GO:0005701"(polytene chromosome chromocenter)|go:"GO:0005703"(polytene chromosome puff)|go:"GO:0005704"(polytene chromosome band)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010369"(chromocenter)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0033697"(obsolete positive regulation of extent of heterochromatin assembly)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051276"(chromosome organization)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070868"(obsolete heterochromatin organization involved in chromatin silencing)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:1900111"(positive regulation of histone H3-K9 dimethylation)|go:"GO:1905632"(protein localization to euchromatin)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1905646"(positive regulation of FACT complex assembly)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P05205|rcsb pdb:1KNA|rcsb pdb:1KNE|rcsb pdb:1Q3L|rcsb pdb:3P7J|rcsb pdb:6ASZ|rcsb pdb:6AT0|rcsb pdb:6MHA go:"GO:0005694"(chromosome) - - figure legend:Fig. 4A, 4B|comment:Co-localization not observed in bon-/- cells|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-salivary_gland)|taxid:7227(Drosophila melanogaster Salivary gland) - 2012/07/02 2014/10/16 rogid:lFLZ7YgoUeb9zUA58E2P1zwFaq07227 rogid:gWEeBI57HBgTrPkRsAgoftkxb+M7227 intact-crc:3BEB4EA43E50EECF|rigid:ZpWsM5716TVEpZHdfXp+DXDuv0A false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q8IN81 uniprotkb:Q9VDK5 intact:EBI-196787|uniprotkb:O44708|uniprotkb:P91618|uniprotkb:P91619|uniprotkb:Q24004|uniprotkb:Q8IN80|uniprotkb:Q8IN82|uniprotkb:Q8IN83|uniprotkb:Q9GU18|uniprotkb:Q9GU19|uniprotkb:Q9GU20|uniprotkb:Q9GU21|uniprotkb:Q9GU22|uniprotkb:Q9VE64|uniprotkb:Q9VE65|uniprotkb:Q9VE66|uniprotkb:Q9VE67|intact:EBI-3407284|uniprotkb:A4V334|uniprotkb:Q29QE0|uniprotkb:Q7KSD2|uniprotkb:Q7KSD5|uniprotkb:Q7KSD6|uniprotkb:Q8IS35|uniprotkb:Q8IS36|intact:EBI-9944780|ensemblmetazoa:FBpp0083063 intact:EBI-3406250|ensemblmetazoa:FBpp0083320 psi-mi:fru_drome(display_long)|uniprotkb:fru(gene name)|psi-mi:fru(display_short)|uniprotkb:BTB-VI(gene name synonym)|uniprotkb:CG14307(orf name) psi-mi:q9vdk5_drome(display_long)|uniprotkb:bon(gene name)|psi-mi:bon(display_short)|uniprotkb:CG15687(gene name synonym)|uniprotkb:CG5206(orf name)|uniprotkb:0241(gene name synonym)|uniprotkb:0249(gene name synonym)|uniprotkb:0434(gene name synonym)|uniprotkb:0487(gene name synonym)|uniprotkb:06(gene name synonym)|uniprotkb:08(gene name synonym)|uniprotkb:12(gene name synonym)|uniprotkb:150268_at(gene name synonym)|uniprotkb:150269_at(gene name synonym)|uniprotkb:20(gene name synonym)|uniprotkb:Bon(gene name synonym)|uniprotkb:Bonus(gene name synonym)|uniprotkb:Dmel\CG5206(gene name synonym)|uniprotkb:anon-WO0118547.418(gene name synonym)|uniprotkb:"l(3)S043420"(gene name synonym)|uniprotkb:Dmel_CG5206(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Ito et al. (2012) imex:IM-17378|pubmed:22682252 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-6248533|imex:IM-17378-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163648.1|refseq:NP_524397.2|refseq:NP_732344.1|refseq:NP_732345.1|refseq:NP_732346.1|refseq:NP_732347.1|refseq:NP_732348.1|refseq:NP_732349.1|refseq:NP_732350.1|refseq:NP_996234.1|refseq:NP_996235.1|refseq:NP_996236.1|refseq:NP_996237.1|refseq:NP_996238.1|flybase:FBgn0004652|dip:DIP-17120N|ensemblmetazoa:FBgn0004652(gene)|ensemblmetazoa:FBtr0083643(transcript)|go:"GO:0002118"(aggressive behavior)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007530"(sex determination)|go:"GO:0007617"(mating behavior)|go:"GO:0007620"(copulation)|go:"GO:0008049"(male courtship behavior)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0016543"(male courtship behavior, orientation prior to leg tapping and wing vibration)|go:"GO:0016544"(male courtship behavior, tapping to detect pheromone)|go:"GO:0016545"(male courtship behavior, veined wing vibration)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0045433"(male courtship behavior, veined wing generated song production)|go:"GO:0046661"(male sex differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048047"(mating behavior, sex discrimination)|go:"GO:0048065"(male courtship behavior, veined wing extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060179"(male mating behavior)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 ensemblmetazoa:FBgn0023097(gene)|ensemblmetazoa:FBtr0083912(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|flybase:FBgn0023097|refseq:NP_524724.2 go:"GO:0005694"(chromosome) - - figure legend:Fig. 4A, 4B|comment:Co-localization not observed in bon-/- cells|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-salivary_gland)|taxid:7227(Drosophila melanogaster Salivary gland) - 2012/07/02 2014/10/16 rogid:lFLZ7YgoUeb9zUA58E2P1zwFaq07227 rogid:Ph5VHrWUFpRMCZQF4iYE7WHxy6M7227 intact-crc:3BEB4EA43E50EECF|rigid:ZpWsM5716TVEpZHdfXp+DXDuv0A false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q8IN81 uniprotkb:Q94517 intact:EBI-196787|uniprotkb:O44708|uniprotkb:P91618|uniprotkb:P91619|uniprotkb:Q24004|uniprotkb:Q8IN80|uniprotkb:Q8IN82|uniprotkb:Q8IN83|uniprotkb:Q9GU18|uniprotkb:Q9GU19|uniprotkb:Q9GU20|uniprotkb:Q9GU21|uniprotkb:Q9GU22|uniprotkb:Q9VE64|uniprotkb:Q9VE65|uniprotkb:Q9VE66|uniprotkb:Q9VE67|intact:EBI-3407284|uniprotkb:A4V334|uniprotkb:Q29QE0|uniprotkb:Q7KSD2|uniprotkb:Q7KSD5|uniprotkb:Q7KSD6|uniprotkb:Q8IS35|uniprotkb:Q8IS36|intact:EBI-9944780|ensemblmetazoa:FBpp0083063 intact:EBI-302197|uniprotkb:O17429|uniprotkb:O77213|uniprotkb:Q9VZA1|ensemblmetazoa:FBpp0073173 psi-mi:fru_drome(display_long)|uniprotkb:fru(gene name)|psi-mi:fru(display_short)|uniprotkb:BTB-VI(gene name synonym)|uniprotkb:CG14307(orf name) psi-mi:hdac1_drome(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:Rpd3(gene name synonym)|uniprotkb:CG7471(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Ito et al. (2012) imex:IM-17378|pubmed:22682252 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-6248524|imex:IM-17378-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163648.1|refseq:NP_524397.2|refseq:NP_732344.1|refseq:NP_732345.1|refseq:NP_732346.1|refseq:NP_732347.1|refseq:NP_732348.1|refseq:NP_732349.1|refseq:NP_732350.1|refseq:NP_996234.1|refseq:NP_996235.1|refseq:NP_996236.1|refseq:NP_996237.1|refseq:NP_996238.1|flybase:FBgn0004652|dip:DIP-17120N|ensemblmetazoa:FBgn0004652(gene)|ensemblmetazoa:FBtr0083643(transcript)|go:"GO:0002118"(aggressive behavior)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007530"(sex determination)|go:"GO:0007617"(mating behavior)|go:"GO:0007620"(copulation)|go:"GO:0008049"(male courtship behavior)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0016543"(male courtship behavior, orientation prior to leg tapping and wing vibration)|go:"GO:0016544"(male courtship behavior, tapping to detect pheromone)|go:"GO:0016545"(male courtship behavior, veined wing vibration)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0045433"(male courtship behavior, veined wing generated song production)|go:"GO:0046661"(male sex differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048047"(mating behavior, sex discrimination)|go:"GO:0048065"(male courtship behavior, veined wing extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060179"(male mating behavior)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 ensemblmetazoa:FBgn0015805(gene)|ensemblmetazoa:FBtr0073317(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005700"(polytene chromosome)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048477"(oogenesis)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0005705"(polytene chromosome interband)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007350"(blastoderm segmentation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070983"(dendrite guidance)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902692"(regulation of neuroblast proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0031523"(Myb complex)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q94517|reactome:R-DME-1538133|reactome:R-DME-201722|reactome:R-DME-209394|reactome:R-DME-3214815|reactome:R-DME-3769402|reactome:R-DME-6804758|reactome:R-DME-8943724|reactome:R-DME-983231|refseq:NP_647918.2|flybase:FBgn0015805|dip:DIP-29512N go:"GO:0005694"(chromosome) - - figure legend:Fig. 4A, 4B|comment:Co-localization not observed in bon-/- cells|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-salivary_gland)|taxid:7227(Drosophila melanogaster Salivary gland) - 2012/07/02 2014/10/16 rogid:lFLZ7YgoUeb9zUA58E2P1zwFaq07227 rogid:HYHCai8wP8lueOr33vYY32w2pHU7227 intact-crc:E571F044C9883A7C|rigid:wxmX6D9W4DuepgiOiPu2voMJIn4 false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q8IN81 uniprotkb:Q9VDK5 intact:EBI-196787|uniprotkb:O44708|uniprotkb:P91618|uniprotkb:P91619|uniprotkb:Q24004|uniprotkb:Q8IN80|uniprotkb:Q8IN82|uniprotkb:Q8IN83|uniprotkb:Q9GU18|uniprotkb:Q9GU19|uniprotkb:Q9GU20|uniprotkb:Q9GU21|uniprotkb:Q9GU22|uniprotkb:Q9VE64|uniprotkb:Q9VE65|uniprotkb:Q9VE66|uniprotkb:Q9VE67|intact:EBI-3407284|uniprotkb:A4V334|uniprotkb:Q29QE0|uniprotkb:Q7KSD2|uniprotkb:Q7KSD5|uniprotkb:Q7KSD6|uniprotkb:Q8IS35|uniprotkb:Q8IS36|intact:EBI-9944780|ensemblmetazoa:FBpp0083063 intact:EBI-3406250|ensemblmetazoa:FBpp0083320 psi-mi:fru_drome(display_long)|uniprotkb:fru(gene name)|psi-mi:fru(display_short)|uniprotkb:BTB-VI(gene name synonym)|uniprotkb:CG14307(orf name) psi-mi:q9vdk5_drome(display_long)|uniprotkb:bon(gene name)|psi-mi:bon(display_short)|uniprotkb:CG15687(gene name synonym)|uniprotkb:CG5206(orf name)|uniprotkb:0241(gene name synonym)|uniprotkb:0249(gene name synonym)|uniprotkb:0434(gene name synonym)|uniprotkb:0487(gene name synonym)|uniprotkb:06(gene name synonym)|uniprotkb:08(gene name synonym)|uniprotkb:12(gene name synonym)|uniprotkb:150268_at(gene name synonym)|uniprotkb:150269_at(gene name synonym)|uniprotkb:20(gene name synonym)|uniprotkb:Bon(gene name synonym)|uniprotkb:Bonus(gene name synonym)|uniprotkb:Dmel\CG5206(gene name synonym)|uniprotkb:anon-WO0118547.418(gene name synonym)|uniprotkb:"l(3)S043420"(gene name synonym)|uniprotkb:Dmel_CG5206(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Ito et al. (2012) imex:IM-17378|pubmed:22682252 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-6248524|imex:IM-17378-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001163648.1|refseq:NP_524397.2|refseq:NP_732344.1|refseq:NP_732345.1|refseq:NP_732346.1|refseq:NP_732347.1|refseq:NP_732348.1|refseq:NP_732349.1|refseq:NP_732350.1|refseq:NP_996234.1|refseq:NP_996235.1|refseq:NP_996236.1|refseq:NP_996237.1|refseq:NP_996238.1|flybase:FBgn0004652|dip:DIP-17120N|ensemblmetazoa:FBgn0004652(gene)|ensemblmetazoa:FBtr0083643(transcript)|go:"GO:0002118"(aggressive behavior)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007417"(central nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007530"(sex determination)|go:"GO:0007617"(mating behavior)|go:"GO:0007620"(copulation)|go:"GO:0008049"(male courtship behavior)|go:"GO:0016199"(axon midline choice point recognition)|go:"GO:0016543"(male courtship behavior, orientation prior to leg tapping and wing vibration)|go:"GO:0016544"(male courtship behavior, tapping to detect pheromone)|go:"GO:0016545"(male courtship behavior, veined wing vibration)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0045433"(male courtship behavior, veined wing generated song production)|go:"GO:0046661"(male sex differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048047"(mating behavior, sex discrimination)|go:"GO:0048065"(male courtship behavior, veined wing extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060179"(male mating behavior)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 ensemblmetazoa:FBgn0023097(gene)|ensemblmetazoa:FBtr0083912(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|flybase:FBgn0023097|refseq:NP_524724.2 go:"GO:0005694"(chromosome) - - figure legend:Fig. 4A, 4B|comment:Co-localization not observed in bon-/- cells|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome-salivary_gland)|taxid:7227(Drosophila melanogaster Salivary gland) - 2012/07/02 2014/10/16 rogid:lFLZ7YgoUeb9zUA58E2P1zwFaq07227 rogid:Ph5VHrWUFpRMCZQF4iYE7WHxy6M7227 intact-crc:E571F044C9883A7C|rigid:wxmX6D9W4DuepgiOiPu2voMJIn4 false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)