#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:F6VAN0	uniprotkb:Q9Z1T2	intact:EBI-6171558|ensembl:ENSMUSP00000027974|uniprotkb:B2RU98|uniprotkb:Q8BZ84	intact:EBI-6171531|ensembl:ENSMUSP00000022213|uniprotkb:Q9QYS3|uniprotkb:Q9WUE0	psi-mi:atf6a_mouse(display_long)|uniprotkb:Atf6(gene name)|psi-mi:Atf6(display_short)|uniprotkb:Activating transcription factor 6 alpha(gene name synonym)	psi-mi:tsp4_mouse(display_long)|uniprotkb:Thbs4(gene name)|psi-mi:Thbs4(display_short)|uniprotkb:Tsp4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lynch et al. (2012)	pubmed:22682248|imex:IM-17375	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6171556|imex:IM-17375-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007601"(visual perception)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1903893"(positive regulation of ATF6-mediated unfolded protein response)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR029801|reactome:R-MMU-381033|ensembl:ENSMUSG00000026663(gene)|ensembl:ENSMUST00000027974(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|refseq:NP_001074773.1|dip:DIP-59768N	go:"GO:0051451"(myoblast migration)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071603"(endothelial cell-cell adhesion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003367(Thrombospondin type 3 repeat)|interpro:IPR008859(Thrombospondin, C-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017897|interpro:IPR018097|interpro:IPR024665|interpro:IPR028974|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|reactome:R-MMU-186797|ensembl:ENSMUSG00000021702(gene)|ensembl:ENSMUST00000022213(transcript)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007399"(nervous system development)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043237"(laminin-1 binding)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048812"(neuron projection morphogenesis)|refseq:NP_035712.1	-	caution:This sequence has been withdrawn from Uniprot.|crc64:C3ADCF7DF2CB3EC9	-	figure legend:Fig. 5A|comment:Lumenal region identified by  western blot by a specific antibody and molecular weight comparison with the full-length protein.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/06/26	2014/10/16	rogid:nbb8fA8fCizE+gGUx52JpvXIFco10090	rogid:D8Oz68SXyyhYT0lEjkLk8lXDnYI10090	intact-crc:31875D7F7B09FB0D|rigid:ZJqKH0mKQ/6h1mmjPr7jK2OAokA	false	sufficient binding region:471..471-656	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:F6VAN0	uniprotkb:P35441	intact:EBI-6171558|ensembl:ENSMUSP00000027974|uniprotkb:B2RU98|uniprotkb:Q8BZ84	intact:EBI-6171593	psi-mi:atf6a_mouse(display_long)|uniprotkb:Atf6(gene name)|psi-mi:Atf6(display_short)|uniprotkb:Activating transcription factor 6 alpha(gene name synonym)	psi-mi:tsp1_mouse(display_long)|uniprotkb:Thbs1(gene name)|psi-mi:Thbs1(display_short)|uniprotkb:Tsp1(gene name synonym)|uniprotkb:Glycoprotein G(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lynch et al. (2012)	pubmed:22682248|imex:IM-17375	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6171618|imex:IM-17375-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007601"(visual perception)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1903893"(positive regulation of ATF6-mediated unfolded protein response)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR029801|reactome:R-MMU-381033|ensembl:ENSMUSG00000026663(gene)|ensembl:ENSMUST00000027974(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|refseq:NP_001074773.1|dip:DIP-59768N	go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0002581"(negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0002605"(negative regulation of dendritic cell antigen processing and presentation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0043236"(laminin binding)|go:"GO:0070051"(fibrinogen binding)|go:"GO:0070052"(collagen V binding)|go:"GO:0070487"(monocyte aggregation)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030141"(secretory granule)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2001027"(negative regulation of endothelial cell chemotaxis)|reactome:R-MMU-114608|reactome:R-MMU-186797|reactome:R-MMU-216083|reactome:R-MMU-5173214|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009749"(response to glucose)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010748"(negative regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0010751"(negative regulation of nitric oxide mediated signal transduction)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0010757"(negative regulation of plasminogen activation)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0016477"(cell migration)|interpro:IPR001881(EGF-like calcium-binding)|mint:P35441|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR003367(Thrombospondin type 3 repeat)|interpro:IPR017897|interpro:IPR008859(Thrombospondin, C-terminal)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR028499|interpro:IPR028974|interpro:IPR036383	-	caution:This sequence has been withdrawn from Uniprot.|crc64:C3ADCF7DF2CB3EC9	-	figure legend:Fig. 5D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/06/26	2014/10/16	rogid:nbb8fA8fCizE+gGUx52JpvXIFco10090	rogid:0j9TPpvxNW9TNMFkFCNo+9wD3fA10090	intact-crc:C77705B18F43C91E|rigid:pNdqeL/3TIoHx65RPPdFk7Tqy7o	false	flag tag:?-?|sufficient binding region:361-656	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9Z1T2	uniprotkb:F6VAN0	intact:EBI-6171531|ensembl:ENSMUSP00000022213|uniprotkb:Q9QYS3|uniprotkb:Q9WUE0	intact:EBI-6171558|ensembl:ENSMUSP00000027974|uniprotkb:B2RU98|uniprotkb:Q8BZ84	psi-mi:tsp4_mouse(display_long)|uniprotkb:Thbs4(gene name)|psi-mi:Thbs4(display_short)|uniprotkb:Tsp4(gene name synonym)	psi-mi:atf6a_mouse(display_long)|uniprotkb:Atf6(gene name)|psi-mi:Atf6(display_short)|uniprotkb:Activating transcription factor 6 alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lynch et al. (2012)	pubmed:22682248|imex:IM-17375	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6171573|imex:IM-17375-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0051451"(myoblast migration)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071603"(endothelial cell-cell adhesion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003367(Thrombospondin type 3 repeat)|interpro:IPR008859(Thrombospondin, C-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017897|interpro:IPR018097|interpro:IPR024665|interpro:IPR028974|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|reactome:R-MMU-186797|ensembl:ENSMUSG00000021702(gene)|ensembl:ENSMUST00000022213(transcript)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007399"(nervous system development)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043237"(laminin-1 binding)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048812"(neuron projection morphogenesis)|refseq:NP_035712.1	go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007601"(visual perception)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1903893"(positive regulation of ATF6-mediated unfolded protein response)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR029801|reactome:R-MMU-381033|ensembl:ENSMUSG00000026663(gene)|ensembl:ENSMUST00000027974(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|refseq:NP_001074773.1|dip:DIP-59768N	-	-	caution:This sequence has been withdrawn from Uniprot.|crc64:C3ADCF7DF2CB3EC9	figure legend:Fig. 5C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/06/26	2014/10/16	rogid:D8Oz68SXyyhYT0lEjkLk8lXDnYI10090	rogid:nbb8fA8fCizE+gGUx52JpvXIFco10090	intact-crc:C465C06D8379E143|rigid:ZJqKH0mKQ/6h1mmjPr7jK2OAokA	false	glutathione s tranferase tag:?-?	flag tag:?-?|sufficient binding region:471-656	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P35443	uniprotkb:F6VAN0	intact:EBI-2530989|uniprotkb:B2R909|uniprotkb:Q86TG2|ensembl:ENSP00000339730	intact:EBI-6171558|ensembl:ENSMUSP00000027974|uniprotkb:B2RU98|uniprotkb:Q8BZ84	psi-mi:tsp4_human(display_long)|uniprotkb:THBS4(gene name)|psi-mi:THBS4(display_short)|uniprotkb:TSP4(gene name synonym)	psi-mi:atf6a_mouse(display_long)|uniprotkb:Atf6(gene name)|psi-mi:Atf6(display_short)|uniprotkb:Activating transcription factor 6 alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lynch et al. (2012)	pubmed:22682248|imex:IM-17375	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6171629|imex:IM-17375-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113296(gene)|ensembl:ENST00000350881(transcript)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048771"(tissue remodeling)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051451"(myoblast migration)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071603"(endothelial cell-cell adhesion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR003367(Thrombospondin type 3 repeat)|interpro:IPR008859(Thrombospondin, C-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017897|interpro:IPR018097|interpro:IPR024665|interpro:IPR028974|reactome:R-HSA-186797|interpro:IPR001881(EGF-like calcium-binding)|refseq:NP_001293143.1|refseq:NP_001293142.1|refseq:NP_001293141.1|refseq:NP_003239.2	go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007601"(visual perception)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1903893"(positive regulation of ATF6-mediated unfolded protein response)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR029801|reactome:R-MMU-381033|ensembl:ENSMUSG00000026663(gene)|ensembl:ENSMUST00000027974(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|refseq:NP_001074773.1|dip:DIP-59768N	-	-	caution:This sequence has been withdrawn from Uniprot.|crc64:C3ADCF7DF2CB3EC9	figure legend:Fig. 5F|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/06/26	2014/10/16	rogid:mHu4nAMFTkamxKsoSTHFxj0vA6w9606	rogid:nbb8fA8fCizE+gGUx52JpvXIFco10090	intact-crc:AED9FA50A0D6CC1C|rigid:XK7z4VTPvj/EWoN/HBD4rruSLOQ	false	glutathione s tranferase tag:?-?|sufficient binding region:464-716(IPR017897)	flag tag:?-?|sufficient binding region:361-656	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:F6VAN0	uniprotkb:Q9Z1T2	intact:EBI-6171558|ensembl:ENSMUSP00000027974|uniprotkb:B2RU98|uniprotkb:Q8BZ84	intact:EBI-6171531|ensembl:ENSMUSP00000022213|uniprotkb:Q9QYS3|uniprotkb:Q9WUE0	psi-mi:atf6a_mouse(display_long)|uniprotkb:Atf6(gene name)|psi-mi:Atf6(display_short)|uniprotkb:Activating transcription factor 6 alpha(gene name synonym)	psi-mi:tsp4_mouse(display_long)|uniprotkb:Thbs4(gene name)|psi-mi:Thbs4(display_short)|uniprotkb:Tsp4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lynch et al. (2012)	pubmed:22682248|imex:IM-17375	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6171663|imex:IM-17375-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007601"(visual perception)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:1903893"(positive regulation of ATF6-mediated unfolded protein response)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR029801|reactome:R-MMU-381033|ensembl:ENSMUSG00000026663(gene)|ensembl:ENSMUST00000027974(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|refseq:NP_001074773.1|dip:DIP-59768N	go:"GO:0051451"(myoblast migration)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071603"(endothelial cell-cell adhesion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003367(Thrombospondin type 3 repeat)|interpro:IPR008859(Thrombospondin, C-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017897|interpro:IPR018097|interpro:IPR024665|interpro:IPR028974|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|reactome:R-MMU-186797|ensembl:ENSMUSG00000021702(gene)|ensembl:ENSMUST00000022213(transcript)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007399"(nervous system development)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0043237"(laminin-1 binding)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048771"(tissue remodeling)|go:"GO:0048812"(neuron projection morphogenesis)|refseq:NP_035712.1	-	caution:This sequence has been withdrawn from Uniprot.|crc64:C3ADCF7DF2CB3EC9	-	figure legend:Fig. 5G|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2012/06/26	2014/10/16	rogid:nbb8fA8fCizE+gGUx52JpvXIFco10090	rogid:D8Oz68SXyyhYT0lEjkLk8lXDnYI10090	intact-crc:B2A03B8A245F0BA1|rigid:ZJqKH0mKQ/6h1mmjPr7jK2OAokA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)