#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O81472 uniprotkb:Q39024 intact:EBI-6271434|ensemblplants:AT4G08480.1 intact:EBI-994375|uniprotkb:B2BDE5|uniprotkb:B2BDE6|uniprotkb:B2BDE8|uniprotkb:B2BDG2|uniprotkb:Q45V20|uniprotkb:Q9M136|uniprotkb:O04597|ensemblplants:AT4G01370.1 psi-mi:mp3k2_arath(display_long)|uniprotkb:MEKK2(gene name)|psi-mi:MEKK2(display_short)|uniprotkb:MAPK/ERK kinase kinase 2(gene name synonym)|uniprotkb:MAPKKK9(gene name synonym)|uniprotkb:Protein SUPPRESSOR OF MKK1 MKK2 1(gene name synonym)|uniprotkb:SUMM1(gene name synonym)|uniprotkb:T15F16.3(orf name)|uniprotkb:At4g08480(locus name) psi-mi:mpk4_arath(display_long)|uniprotkb:MPK4(gene name)|psi-mi:MPK4(display_short)|uniprotkb:At4g01370(locus name)|uniprotkb:F2N1.1(orf name)|uniprotkb:F2N1_2-t(orf name) psi-mi:"MI:0018"(two hybrid) Kong et al. (2012) pubmed:22643122|imex:IM-17708 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6271432|imex:IM-17708-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblplants:AT4G08480(gene)|ensemblplants:AT4G08480.1(transcript)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0022622"(root system development)|go:"GO:0031347"(regulation of defense response)|go:"GO:0045087"(innate immune response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902065"(response to L-glutamate)|refseq:NP_192588.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core) interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:NP_192046.1|ensemblplants:AT4G01370(gene)|ensemblplants:AT4G01370.1(transcript)|go:"GO:0000911"(cytokinesis by cell plate formation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0009409"(response to cold)|go:"GO:0009504"(cell plate)|go:"GO:0009555"(pollen development)|go:"GO:0009620"(response to fungus)|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009861"(jasmonic acid and ethylene-dependent systemic resistance)|go:"GO:0009862"(systemic acquired resistance, salicylic acid mediated signaling pathway)|go:"GO:0009651"(response to salt stress)|go:"GO:0010119"(regulation of stomatal movement)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042539"(hypotonic salinity response)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0045087"(innate immune response)|go:"GO:0071244"(cellular response to carbon dioxide)|go:"GO:0090333"(regulation of stomatal closure)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0009868"(jasmonic acid and ethylene-dependent systemic resistance, jasmonic acid mediated signaling pathway)|mint:Q39024 - - - figure legend:6a and 6b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2012/08/20 2014/10/16 rogid:7TA6Fbq9qxrpnlhQcvpn2Dp/HaM3702 rogid:jyFz90mZEtRmnkT/Df46+7LKPjU3702 intact-crc:490B597862A0CB97|rigid:iBs/WB8zCfbOr6/BAw0ZeGZdDrs false necessary binding region:1-494 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q39024 uniprotkb:O81472 intact:EBI-994375|uniprotkb:B2BDE5|uniprotkb:B2BDE6|uniprotkb:B2BDE8|uniprotkb:B2BDG2|uniprotkb:Q45V20|uniprotkb:Q9M136|uniprotkb:O04597|ensemblplants:AT4G01370.1 intact:EBI-6271434|ensemblplants:AT4G08480.1 psi-mi:mpk4_arath(display_long)|uniprotkb:MPK4(gene name)|psi-mi:MPK4(display_short)|uniprotkb:At4g01370(locus name)|uniprotkb:F2N1.1(orf name)|uniprotkb:F2N1_2-t(orf name) psi-mi:mp3k2_arath(display_long)|uniprotkb:MEKK2(gene name)|psi-mi:MEKK2(display_short)|uniprotkb:MAPK/ERK kinase kinase 2(gene name synonym)|uniprotkb:MAPKKK9(gene name synonym)|uniprotkb:Protein SUPPRESSOR OF MKK1 MKK2 1(gene name synonym)|uniprotkb:SUMM1(gene name synonym)|uniprotkb:T15F16.3(orf name)|uniprotkb:At4g08480(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kong et al. (2012) pubmed:22643122|imex:IM-17708 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6271463|imex:IM-17708-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:NP_192046.1|ensemblplants:AT4G01370(gene)|ensemblplants:AT4G01370.1(transcript)|go:"GO:0000911"(cytokinesis by cell plate formation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0009409"(response to cold)|go:"GO:0009504"(cell plate)|go:"GO:0009555"(pollen development)|go:"GO:0009620"(response to fungus)|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009861"(jasmonic acid and ethylene-dependent systemic resistance)|go:"GO:0009862"(systemic acquired resistance, salicylic acid mediated signaling pathway)|go:"GO:0009651"(response to salt stress)|go:"GO:0010119"(regulation of stomatal movement)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042539"(hypotonic salinity response)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0045087"(innate immune response)|go:"GO:0071244"(cellular response to carbon dioxide)|go:"GO:0090333"(regulation of stomatal closure)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0009868"(jasmonic acid and ethylene-dependent systemic resistance, jasmonic acid mediated signaling pathway)|mint:Q39024 ensemblplants:AT4G08480(gene)|ensemblplants:AT4G08480.1(transcript)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0022622"(root system development)|go:"GO:0031347"(regulation of defense response)|go:"GO:0045087"(innate immune response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902065"(response to L-glutamate)|refseq:NP_192588.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core) - - - figure legend:6c|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") - 2012/08/20 2014/10/16 rogid:jyFz90mZEtRmnkT/Df46+7LKPjU3702 rogid:7TA6Fbq9qxrpnlhQcvpn2Dp/HaM3702 intact-crc:9528119D64D9C807|rigid:iBs/WB8zCfbOr6/BAw0ZeGZdDrs false - flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O81472 uniprotkb:Q39024 intact:EBI-6271434|ensemblplants:AT4G08480.1 intact:EBI-994375|uniprotkb:B2BDE5|uniprotkb:B2BDE6|uniprotkb:B2BDE8|uniprotkb:B2BDG2|uniprotkb:Q45V20|uniprotkb:Q9M136|uniprotkb:O04597|ensemblplants:AT4G01370.1 psi-mi:mp3k2_arath(display_long)|uniprotkb:MEKK2(gene name)|psi-mi:MEKK2(display_short)|uniprotkb:MAPK/ERK kinase kinase 2(gene name synonym)|uniprotkb:MAPKKK9(gene name synonym)|uniprotkb:Protein SUPPRESSOR OF MKK1 MKK2 1(gene name synonym)|uniprotkb:SUMM1(gene name synonym)|uniprotkb:T15F16.3(orf name)|uniprotkb:At4g08480(locus name) psi-mi:mpk4_arath(display_long)|uniprotkb:MPK4(gene name)|psi-mi:MPK4(display_short)|uniprotkb:At4g01370(locus name)|uniprotkb:F2N1.1(orf name)|uniprotkb:F2N1_2-t(orf name) psi-mi:"MI:0424"(protein kinase assay) Kong et al. (2012) pubmed:22643122|imex:IM-17708 taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6271479|imex:IM-17708-3 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblplants:AT4G08480(gene)|ensemblplants:AT4G08480.1(transcript)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0022622"(root system development)|go:"GO:0031347"(regulation of defense response)|go:"GO:0045087"(innate immune response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902065"(response to L-glutamate)|refseq:NP_192588.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core) interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:NP_192046.1|ensemblplants:AT4G01370(gene)|ensemblplants:AT4G01370.1(transcript)|go:"GO:0000911"(cytokinesis by cell plate formation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007112"(male meiosis cytokinesis)|go:"GO:0009409"(response to cold)|go:"GO:0009504"(cell plate)|go:"GO:0009555"(pollen development)|go:"GO:0009620"(response to fungus)|go:"GO:0009737"(response to abscisic acid)|go:"GO:0009861"(jasmonic acid and ethylene-dependent systemic resistance)|go:"GO:0009862"(systemic acquired resistance, salicylic acid mediated signaling pathway)|go:"GO:0009651"(response to salt stress)|go:"GO:0010119"(regulation of stomatal movement)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042539"(hypotonic salinity response)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0045087"(innate immune response)|go:"GO:0071244"(cellular response to carbon dioxide)|go:"GO:0090333"(regulation of stomatal closure)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0009868"(jasmonic acid and ethylene-dependent systemic resistance, jasmonic acid mediated signaling pathway)|mint:Q39024 go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity) - - figure legend:6d|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/08/20 2014/10/16 rogid:7TA6Fbq9qxrpnlhQcvpn2Dp/HaM3702 rogid:jyFz90mZEtRmnkT/Df46+7LKPjU3702 intact-crc:3B304BCF257F7050|rigid:iBs/WB8zCfbOr6/BAw0ZeGZdDrs false sufficient binding region:1-500|his tag:?-? mutation disrupting interaction:186-186 - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography)