#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8N157	uniprotkb:P39060	intact:EBI-1049056|uniprotkb:Q504T3|uniprotkb:Q5TCP9|uniprotkb:Q6P098|uniprotkb:Q6PIT6|uniprotkb:Q8NDX0|uniprotkb:Q9H0H2|uniprotkb:Q4FD35|uniprotkb:E1P584|ensembl:ENSP00000265602|ensembl:ENSP00000356774|ensembl:ENSP00000388650|ensembl:ENSP00000504965|ensembl:ENSP00000505121|ensembl:ENSP00000505666|ensembl:ENSP00000506005|ensembl:ENSP00000506604	intact:EBI-981314|uniprotkb:Q58EX6|uniprotkb:Q6RZ39|uniprotkb:Q6RZ40|uniprotkb:Q6RZ41|uniprotkb:Q8N4S4|uniprotkb:Q8WXI5|uniprotkb:Q96T70|uniprotkb:Q9UK38|uniprotkb:Q9Y6Q7|uniprotkb:A8MVI4|ensembl:ENSP00000352798|uniprotkb:Q9Y6Q8	psi-mi:ahi1_human(display_long)|uniprotkb:Abelson helper integration site 1 protein homolog(gene name synonym)|uniprotkb:AHI1(gene name)|psi-mi:AHI1(display_short)	psi-mi:coia1_human(display_long)|uniprotkb:COL18A1(gene name)|psi-mi:COL18A1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2012)	pubmed:22623184|imex:IM-17411	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6249359|imex:IM-17411-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128302.1|refseq:NP_001128303.1|refseq:NP_001128304.1|refseq:NP_060121.3|refseq:XP_011534212.1|refseq:XP_011534213.1|refseq:XP_016866466.1|refseq:XP_016866473.1|ensembl:ENSG00000135541(gene)|ensembl:ENST00000265602(transcript)|ensembl:ENST00000367800(transcript)|ensembl:ENST00000457866(transcript)|ensembl:ENST00000681022(transcript)|ensembl:ENST00000681340(transcript)|ensembl:ENST00000681365(transcript)|ensembl:ENST00000681522(transcript)|ensembl:ENST00000681841(transcript)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005929"(cilium)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007417"(central nervous system development)|go:"GO:0010842"(retina layer formation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030862"(positive regulation of polarized epithelial cell differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035844"(cloaca development)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0039008"(pronephric nephron tubule morphogenesis)|go:"GO:0039023"(pronephric duct morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050795"(regulation of behavior)|go:"GO:0060271"(cilium assembly)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070121"(Kupffer's vesicle development)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071599"(otic vesicle development)|go:"GO:0097730"(non-motile cilium)|interpro:IPR001452(Src homology-3)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR035832|interpro:IPR036028|interpro:IPR036322|rcsb pdb:4ESR|reactome:R-HSA-5620912	refseq:NP_085059.2|refseq:NP_569712.2|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR020067|interpro:IPR035523|interpro:IPR036790|rcsb pdb:1BNL|rcsb pdb:3HON|rcsb pdb:3HSH|reactome:R-HSA-1442490|reactome:R-HSA-1592389|reactome:R-HSA-1650814|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-8948216|ensembl:ENSG00000182871(gene)|ensembl:ENST00000359759(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0007601"(visual perception)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001791(Laminin G)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR010363(Protein of unknown function DUF959, collagen XVIII, N-terminal)|interpro:IPR010515(Collagenase NC10 and endostatin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|refseq:NP_569711.2	-	-	-	figure legend:table 2 and figure 3a|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/19	2014/10/16	rogid:T5wpoUyP0fVpKmJw1bu+80PEtw09606	rogid:wLRIpnIxV06w/L+TD0ZldrjEsVs9606	intact-crc:3D3D1C2A57A4DCC4|rigid:l82bCZUorUT8IvdzyAj7TfjBMLQ	false	sufficient binding region:1048-1116|his tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N157	uniprotkb:P50570	intact:EBI-1049056|uniprotkb:Q504T3|uniprotkb:Q5TCP9|uniprotkb:Q6P098|uniprotkb:Q6PIT6|uniprotkb:Q8NDX0|uniprotkb:Q9H0H2|uniprotkb:Q4FD35|uniprotkb:E1P584|ensembl:ENSP00000265602|ensembl:ENSP00000356774|ensembl:ENSP00000388650|ensembl:ENSP00000504965|ensembl:ENSP00000505121|ensembl:ENSP00000505666|ensembl:ENSP00000506005|ensembl:ENSP00000506604	intact:EBI-346547|uniprotkb:Q7Z5S3|uniprotkb:Q5I0Y0|uniprotkb:Q9UPH4|intact:EBI-3959204|uniprotkb:A8K1B6|uniprotkb:E7EV30|uniprotkb:K7ESI9|intact:EBI-5912046|uniprotkb:E9PEQ4|ensembl:ENSP00000347890	psi-mi:ahi1_human(display_long)|uniprotkb:Abelson helper integration site 1 protein homolog(gene name synonym)|uniprotkb:AHI1(gene name)|psi-mi:AHI1(display_short)	psi-mi:dyn2_human(display_long)|uniprotkb:DNM2(gene name)|psi-mi:DNM2(display_short)|uniprotkb:DYN2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2012)	pubmed:22623184|imex:IM-17411	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6249359|imex:IM-17411-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128302.1|refseq:NP_001128303.1|refseq:NP_001128304.1|refseq:NP_060121.3|refseq:XP_011534212.1|refseq:XP_011534213.1|refseq:XP_016866466.1|refseq:XP_016866473.1|ensembl:ENSG00000135541(gene)|ensembl:ENST00000265602(transcript)|ensembl:ENST00000367800(transcript)|ensembl:ENST00000457866(transcript)|ensembl:ENST00000681022(transcript)|ensembl:ENST00000681340(transcript)|ensembl:ENST00000681365(transcript)|ensembl:ENST00000681522(transcript)|ensembl:ENST00000681841(transcript)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005929"(cilium)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007417"(central nervous system development)|go:"GO:0010842"(retina layer formation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030862"(positive regulation of polarized epithelial cell differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035844"(cloaca development)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0039008"(pronephric nephron tubule morphogenesis)|go:"GO:0039023"(pronephric duct morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050795"(regulation of behavior)|go:"GO:0060271"(cilium assembly)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070121"(Kupffer's vesicle development)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071599"(otic vesicle development)|go:"GO:0097730"(non-motile cilium)|interpro:IPR001452(Src homology-3)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR035832|interpro:IPR036028|interpro:IPR036322|rcsb pdb:4ESR|reactome:R-HSA-5620912	refseq:NP_004936.2|refseq:NP_001005360.1|refseq:NP_001005361.1|refseq:NP_001005362.1|refseq:NP_001177645.1|dip:DIP-31244N|reactome:R-HSA-203641|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-8856828|reactome:R-HSA-9031628|reactome:R-HSA-196025|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071245"(cellular response to carbon monoxide)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P50570|rcsb pdb:2YS1|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-190873|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000079805(gene)|ensembl:ENST00000355667(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)	-	-	-	figure legend:table 2 and figure 3a|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/19	2014/10/16	rogid:T5wpoUyP0fVpKmJw1bu+80PEtw09606	rogid:BAUEy6Iju72PTot46Xhz75cQTQs9606	intact-crc:3D3D1C2A57A4DCC4|rigid:l82bCZUorUT8IvdzyAj7TfjBMLQ	false	sufficient binding region:1048-1116|his tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8N157	uniprotkb:P50570	intact:EBI-1049056|uniprotkb:Q504T3|uniprotkb:Q5TCP9|uniprotkb:Q6P098|uniprotkb:Q6PIT6|uniprotkb:Q8NDX0|uniprotkb:Q9H0H2|uniprotkb:Q4FD35|uniprotkb:E1P584|ensembl:ENSP00000265602|ensembl:ENSP00000356774|ensembl:ENSP00000388650|ensembl:ENSP00000504965|ensembl:ENSP00000505121|ensembl:ENSP00000505666|ensembl:ENSP00000506005|ensembl:ENSP00000506604	intact:EBI-346547|uniprotkb:Q7Z5S3|uniprotkb:Q5I0Y0|uniprotkb:Q9UPH4|intact:EBI-3959204|uniprotkb:A8K1B6|uniprotkb:E7EV30|uniprotkb:K7ESI9|intact:EBI-5912046|uniprotkb:E9PEQ4|ensembl:ENSP00000347890	psi-mi:ahi1_human(display_long)|uniprotkb:Abelson helper integration site 1 protein homolog(gene name synonym)|uniprotkb:AHI1(gene name)|psi-mi:AHI1(display_short)	psi-mi:dyn2_human(display_long)|uniprotkb:DNM2(gene name)|psi-mi:DNM2(display_short)|uniprotkb:DYN2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Liu et al. (2012)	pubmed:22623184|imex:IM-17411	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6249377|imex:IM-17411-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128302.1|refseq:NP_001128303.1|refseq:NP_001128304.1|refseq:NP_060121.3|refseq:XP_011534212.1|refseq:XP_011534213.1|refseq:XP_016866466.1|refseq:XP_016866473.1|ensembl:ENSG00000135541(gene)|ensembl:ENST00000265602(transcript)|ensembl:ENST00000367800(transcript)|ensembl:ENST00000457866(transcript)|ensembl:ENST00000681022(transcript)|ensembl:ENST00000681340(transcript)|ensembl:ENST00000681365(transcript)|ensembl:ENST00000681522(transcript)|ensembl:ENST00000681841(transcript)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005929"(cilium)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007417"(central nervous system development)|go:"GO:0010842"(retina layer formation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030862"(positive regulation of polarized epithelial cell differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035844"(cloaca development)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0039008"(pronephric nephron tubule morphogenesis)|go:"GO:0039023"(pronephric duct morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050795"(regulation of behavior)|go:"GO:0060271"(cilium assembly)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070121"(Kupffer's vesicle development)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071599"(otic vesicle development)|go:"GO:0097730"(non-motile cilium)|interpro:IPR001452(Src homology-3)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR035832|interpro:IPR036028|interpro:IPR036322|rcsb pdb:4ESR|reactome:R-HSA-5620912	refseq:NP_004936.2|refseq:NP_001005360.1|refseq:NP_001005361.1|refseq:NP_001005362.1|refseq:NP_001177645.1|dip:DIP-31244N|reactome:R-HSA-203641|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-8856828|reactome:R-HSA-9031628|reactome:R-HSA-196025|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071245"(cellular response to carbon monoxide)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P50570|rcsb pdb:2YS1|reactome:R-HSA-166016|reactome:R-HSA-177504|reactome:R-HSA-190873|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|ensembl:ENSG00000079805(gene)|ensembl:ENST00000355667(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)	-	-	-	figure legend:fig 3c|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/07/19	2014/10/16	rogid:T5wpoUyP0fVpKmJw1bu+80PEtw09606	rogid:BAUEy6Iju72PTot46Xhz75cQTQs9606	intact-crc:7E841D9F3EC6C5FD|rigid:9nLqxdlezrwIeFUTiC9faSBuSyQ	false	sufficient binding region:606..606-1196..1196|ha tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8N157	uniprotkb:P39054	intact:EBI-1049056|uniprotkb:Q504T3|uniprotkb:Q5TCP9|uniprotkb:Q6P098|uniprotkb:Q6PIT6|uniprotkb:Q8NDX0|uniprotkb:Q9H0H2|uniprotkb:Q4FD35|uniprotkb:E1P584|ensembl:ENSP00000265602|ensembl:ENSP00000356774|ensembl:ENSP00000388650|ensembl:ENSP00000504965|ensembl:ENSP00000505121|ensembl:ENSP00000505666|ensembl:ENSP00000506005|ensembl:ENSP00000506604	intact:EBI-642337|uniprotkb:Q9DBE1|ensembl:ENSMUSP00000133564	psi-mi:ahi1_human(display_long)|uniprotkb:Abelson helper integration site 1 protein homolog(gene name synonym)|uniprotkb:AHI1(gene name)|psi-mi:AHI1(display_short)	psi-mi:dyn2_mouse(display_long)|uniprotkb:Dynamin UDNM(gene name synonym)|uniprotkb:Dnm2(gene name)|psi-mi:Dnm2(display_short)|uniprotkb:Dyn2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Liu et al. (2012)	pubmed:22623184|imex:IM-17411	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6249394|imex:IM-17411-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001128302.1|refseq:NP_001128303.1|refseq:NP_001128304.1|refseq:NP_060121.3|refseq:XP_011534212.1|refseq:XP_011534213.1|refseq:XP_016866466.1|refseq:XP_016866473.1|ensembl:ENSG00000135541(gene)|ensembl:ENST00000265602(transcript)|ensembl:ENST00000367800(transcript)|ensembl:ENST00000457866(transcript)|ensembl:ENST00000681022(transcript)|ensembl:ENST00000681340(transcript)|ensembl:ENST00000681365(transcript)|ensembl:ENST00000681522(transcript)|ensembl:ENST00000681841(transcript)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001947"(heart looping)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005929"(cilium)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007417"(central nervous system development)|go:"GO:0010842"(retina layer formation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030862"(positive regulation of polarized epithelial cell differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035844"(cloaca development)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0036038"(MKS complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0039008"(pronephric nephron tubule morphogenesis)|go:"GO:0039023"(pronephric duct morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050795"(regulation of behavior)|go:"GO:0060271"(cilium assembly)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070121"(Kupffer's vesicle development)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071599"(otic vesicle development)|go:"GO:0097730"(non-motile cilium)|interpro:IPR001452(Src homology-3)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR035832|interpro:IPR036028|interpro:IPR036322|rcsb pdb:4ESR|reactome:R-HSA-5620912	refseq:NP_001240822.1|refseq:NP_001240823.1|refseq:NP_031897.2|ensembl:ENSMUSG00000033335(gene)|ensembl:ENSMUST00000172482(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061025"(membrane fusion)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035904"(aorta development)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P39054|reactome:R-MMU-166016|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-203641|reactome:R-MMU-2132295|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-437239|reactome:R-MMU-8856828	-	-	-	figure legend:fig 3d|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-ba_f3)|taxid:10090(Mouse pro B cells IL-3 dependent)	-	2012/07/19	2014/10/16	rogid:T5wpoUyP0fVpKmJw1bu+80PEtw09606	rogid:+f91mVsvYvuhsUOSzw37RpZv/2M10090	intact-crc:1AE24DFA4144C5AF|rigid:mVRGS+oJr8niauXMA44nJQawyTE	false	necessary binding region:1048-1116	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)