#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P03120	uniprotkb:P03114	intact:EBI-1779322|uniprotkb:Q71BI4	intact:EBI-7387308|uniprotkb:P03115|uniprotkb:Q71BI5|intact:MINT-1526142	psi-mi:ve2_hpv16(display_long)|uniprotkb:E2(gene name)|psi-mi:E2(display_short)	psi-mi:ve1_hpv16(display_long)|uniprotkb:E1(gene name)|psi-mi:E1(display_short)|uniprotkb:ATP-dependent helicase E1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Johansson et al. (2012)	doi:10.1038/emboj.2012.147|pubmed:22617423|imex:IM-18521|mint:MINT-8393711	taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16)	taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7894484|mint:MINT-8393726|imex:IM-18521-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_041328.1|dip:DIP-44574N|mint:P03120|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044163"(host cytoskeleton)|interpro:IPR000427(E2 early regulatory protein, C-terminal)|interpro:IPR001866(E2 early regulatory protein, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033668|interpro:IPR035975|interpro:IPR036050|interpro:IPR042503|interpro:IPR042504|rcsb pdb:1BY9|rcsb pdb:1DTO|rcsb pdb:1R8P|rcsb pdb:1ZZF|rcsb pdb:2NNU|rcsb pdb:2Q79|rcsb pdb:3MI7|mint:MINT-8393728(identity)	mint:P03114|interpro:IPR016393(Replication protein E1, papillomavirus)|interpro:IPR027417|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|interpro:IPR014000(DNA helicase E1 protein, N-terminal, Papillomavirus)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006260"(DNA replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001177(DNA helicase E1 protein, C-terminal, Papillomavirus)|mint:MINT-8393731(identity)	-	-	comment:mint|comment:homomint|function:ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins	figure legend:f9a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/09/24	2014/10/16	rogid:0/XZ8yUPpKVdUvpKjNxjHHQnmAE333760	rogid:1k8b6WS2HBpWDus+zuWQyaRg/PU333760	intact-crc:B96123D7F6178955|rigid:UtgNIDw5d62qRhBFGHyC0qvwPus	false	glutathione s tranferase tag:?-?(MINT-8393733)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P03120	uniprotkb:Q10568	intact:EBI-1779322|uniprotkb:Q71BI4	intact:EBI-7894460|intact:UNK-5887233|ensembl:ENSBTAP00000013500	psi-mi:ve2_hpv16(display_long)|uniprotkb:E2(gene name)|psi-mi:E2(display_short)	psi-mi:cpsf2_bovin(display_long)|uniprotkb:CPSF2(gene name)|psi-mi:CPSF2(display_short)|uniprotkb:CPSF100(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 100 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Johansson et al. (2012)	doi:10.1038/emboj.2012.147|pubmed:22617423|imex:IM-18521|mint:MINT-8393711	taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16)	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7894484|mint:MINT-8393726|imex:IM-18521-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_041328.1|dip:DIP-44574N|mint:P03120|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044163"(host cytoskeleton)|interpro:IPR000427(E2 early regulatory protein, C-terminal)|interpro:IPR001866(E2 early regulatory protein, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033668|interpro:IPR035975|interpro:IPR036050|interpro:IPR042503|interpro:IPR042504|rcsb pdb:1BY9|rcsb pdb:1DTO|rcsb pdb:1R8P|rcsb pdb:1ZZF|rcsb pdb:2NNU|rcsb pdb:2Q79|rcsb pdb:3MI7|mint:MINT-8393728(identity)	refseq:NP_787002.1|refseq:XP_005222184.1|ensembl:ENSBTAG00000010227(gene)|ensembl:ENSBTAT00000013500(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR025069|interpro:IPR027075|interpro:IPR035639|interpro:IPR036866|mint:MINT-8393730(identity)	-	-	comment:mint|function:"Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition"|comment:homomint	figure legend:f9a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/09/24	2014/10/16	rogid:0/XZ8yUPpKVdUvpKjNxjHHQnmAE333760	rogid:FS/rpfuhf+vx861jzxCfoj/75oQ9913	intact-crc:B96123D7F6178955|rigid:UtgNIDw5d62qRhBFGHyC0qvwPus	false	glutathione s tranferase tag:?-?(MINT-8393733)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P03120	uniprotkb:O19137	intact:EBI-1779322|uniprotkb:Q71BI4	intact:EBI-7894441|intact:MINT-8393776|ensembl:ENSBTAP00000002701	psi-mi:ve2_hpv16(display_long)|uniprotkb:E2(gene name)|psi-mi:E2(display_short)	psi-mi:cpsf4_bovin(display_long)|uniprotkb:CPSF4(gene name)|psi-mi:CPSF4(display_short)|uniprotkb:CPSF30(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 30 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Johansson et al. (2012)	doi:10.1038/emboj.2012.147|pubmed:22617423|imex:IM-18521|mint:MINT-8393711	taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16)	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7894484|mint:MINT-8393726|imex:IM-18521-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_041328.1|dip:DIP-44574N|mint:P03120|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044163"(host cytoskeleton)|interpro:IPR000427(E2 early regulatory protein, C-terminal)|interpro:IPR001866(E2 early regulatory protein, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033668|interpro:IPR035975|interpro:IPR036050|interpro:IPR042503|interpro:IPR042504|rcsb pdb:1BY9|rcsb pdb:1DTO|rcsb pdb:1R8P|rcsb pdb:1ZZF|rcsb pdb:2NNU|rcsb pdb:2Q79|rcsb pdb:3MI7|mint:MINT-8393728(identity)	refseq:NP_776367.1|ensembl:ENSBTAG00000002090(gene)|ensembl:ENSBTAT00000002701(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036855|interpro:IPR036875|interpro:IPR041686|mint:MINT-8393807(identity)	-	-	comment:mint|comment:homomint	figure legend:f9a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/09/24	2014/10/16	rogid:0/XZ8yUPpKVdUvpKjNxjHHQnmAE333760	rogid:TT4WZ7qxsOzGEppHWW+FsDiIpN49913	intact-crc:B96123D7F6178955|rigid:UtgNIDw5d62qRhBFGHyC0qvwPus	false	glutathione s tranferase tag:?-?(MINT-8393733)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P03120	uniprotkb:P79101	intact:EBI-1779322|uniprotkb:Q71BI4	intact:EBI-7894416|intact:MINT-8393774|uniprotkb:Q3MHX7|ensembl:ENSBTAP00000026303	psi-mi:ve2_hpv16(display_long)|uniprotkb:E2(gene name)|psi-mi:E2(display_short)	psi-mi:cpsf3_bovin(display_long)|uniprotkb:CPSF3(gene name)|psi-mi:CPSF3(display_short)|uniprotkb:CPSF73(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 73 kDa subunit(gene name synonym)|uniprotkb:mRNA 3'-end-processing endonuclease CPSF-73(gene name synonym)	psi-mi:"MI:0096"(pull down)	Johansson et al. (2012)	doi:10.1038/emboj.2012.147|pubmed:22617423|imex:IM-18521|mint:MINT-8393711	taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16)	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7894484|mint:MINT-8393726|imex:IM-18521-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_041328.1|dip:DIP-44574N|mint:P03120|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044163"(host cytoskeleton)|interpro:IPR000427(E2 early regulatory protein, C-terminal)|interpro:IPR001866(E2 early regulatory protein, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033668|interpro:IPR035975|interpro:IPR036050|interpro:IPR042503|interpro:IPR042504|rcsb pdb:1BY9|rcsb pdb:1DTO|rcsb pdb:1R8P|rcsb pdb:1ZZF|rcsb pdb:2NNU|rcsb pdb:2Q79|rcsb pdb:3MI7|mint:MINT-8393728(identity)	refseq:NP_776709.1|ensembl:ENSBTAG00000019735(gene)|ensembl:ENSBTAT00000026303(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|mint:MINT-8393806(identity)	-	-	comment:mint|comment:homomint	figure legend:f9a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/09/24	2014/10/16	rogid:0/XZ8yUPpKVdUvpKjNxjHHQnmAE333760	rogid:PzGiogw7aFBVGuRecRNj0BYd2lQ9913	intact-crc:B96123D7F6178955|rigid:UtgNIDw5d62qRhBFGHyC0qvwPus	false	glutathione s tranferase tag:?-?(MINT-8393733)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P03120	uniprotkb:Q10569	intact:EBI-1779322|uniprotkb:Q71BI4	intact:EBI-7894372|intact:UNK-5887240	psi-mi:ve2_hpv16(display_long)|uniprotkb:E2(gene name)|psi-mi:E2(display_short)	psi-mi:cpsf1_bovin(display_long)|uniprotkb:CPSF1(gene name)|psi-mi:CPSF1(display_short)|uniprotkb:CPSF160(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 160 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Johansson et al. (2012)	doi:10.1038/emboj.2012.147|pubmed:22617423|imex:IM-18521|mint:MINT-8393711	taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16)	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7894484|mint:MINT-8393726|imex:IM-18521-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_041328.1|dip:DIP-44574N|mint:P03120|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044163"(host cytoskeleton)|interpro:IPR000427(E2 early regulatory protein, C-terminal)|interpro:IPR001866(E2 early regulatory protein, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033668|interpro:IPR035975|interpro:IPR036050|interpro:IPR042503|interpro:IPR042504|rcsb pdb:1BY9|rcsb pdb:1DTO|rcsb pdb:1R8P|rcsb pdb:1ZZF|rcsb pdb:2NNU|rcsb pdb:2Q79|rcsb pdb:3MI7|mint:MINT-8393728(identity)	refseq:NP_777145.1|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR018846|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|mint:MINT-8393729(identity)	-	-	comment:mint|comment:homomint|function:"Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction"	figure legend:f9a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/09/24	2014/10/16	rogid:0/XZ8yUPpKVdUvpKjNxjHHQnmAE333760	rogid:Tm9KkQqy3xNsdMjNyXX/bcoYdGw9913	intact-crc:B96123D7F6178955|rigid:UtgNIDw5d62qRhBFGHyC0qvwPus	false	glutathione s tranferase tag:?-?(MINT-8393733)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:O19137	uniprotkb:P03120	intact:EBI-7894441|intact:MINT-8393776|ensembl:ENSBTAP00000002701	intact:EBI-1779322|uniprotkb:Q71BI4	psi-mi:cpsf4_bovin(display_long)|uniprotkb:CPSF4(gene name)|psi-mi:CPSF4(display_short)|uniprotkb:CPSF30(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 30 kDa subunit(gene name synonym)	psi-mi:ve2_hpv16(display_long)|uniprotkb:E2(gene name)|psi-mi:E2(display_short)	psi-mi:"MI:0096"(pull down)	Johansson et al. (2012)	doi:10.1038/emboj.2012.147|pubmed:22617423|imex:IM-18521|mint:MINT-8393711	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7894552|mint:MINT-8393743|imex:IM-18521-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_776367.1|ensembl:ENSBTAG00000002090(gene)|ensembl:ENSBTAT00000002701(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036855|interpro:IPR036875|interpro:IPR041686|mint:MINT-8393749(identity)	refseq:NP_041328.1|dip:DIP-44574N|mint:P03120|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044163"(host cytoskeleton)|interpro:IPR000427(E2 early regulatory protein, C-terminal)|interpro:IPR001866(E2 early regulatory protein, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033668|interpro:IPR035975|interpro:IPR036050|interpro:IPR042503|interpro:IPR042504|rcsb pdb:1BY9|rcsb pdb:1DTO|rcsb pdb:1R8P|rcsb pdb:1ZZF|rcsb pdb:2NNU|rcsb pdb:2Q79|rcsb pdb:3MI7|mint:MINT-8393745(identity)	-	comment:mint|comment:homomint	-	figure legend:f9b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/09/24	2014/10/16	rogid:TT4WZ7qxsOzGEppHWW+FsDiIpN49913	rogid:0/XZ8yUPpKVdUvpKjNxjHHQnmAE333760	intact-crc:0B6FE85F43BE286C|rigid:KotDXKvnkOQo2XxKG+k/pvG2Lfs	false	-	glutathione s tranferase tag:?-?(MINT-8393746)	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O19137	uniprotkb:P03120	intact:EBI-7894441|intact:MINT-8393776|ensembl:ENSBTAP00000002701	intact:EBI-1779322|uniprotkb:Q71BI4	psi-mi:cpsf4_bovin(display_long)|uniprotkb:CPSF4(gene name)|psi-mi:CPSF4(display_short)|uniprotkb:CPSF30(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 30 kDa subunit(gene name synonym)	psi-mi:ve2_hpv16(display_long)|uniprotkb:E2(gene name)|psi-mi:E2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Johansson et al. (2012)	doi:10.1038/emboj.2012.147|pubmed:22617423|imex:IM-18521|mint:MINT-8393711	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7894903|mint:MINT-8393760|imex:IM-18521-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_776367.1|ensembl:ENSBTAG00000002090(gene)|ensembl:ENSBTAT00000002701(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036855|interpro:IPR036875|interpro:IPR041686|mint:MINT-8393766(identity)	refseq:NP_041328.1|dip:DIP-44574N|mint:P03120|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044163"(host cytoskeleton)|interpro:IPR000427(E2 early regulatory protein, C-terminal)|interpro:IPR001866(E2 early regulatory protein, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033668|interpro:IPR035975|interpro:IPR036050|interpro:IPR042503|interpro:IPR042504|rcsb pdb:1BY9|rcsb pdb:1DTO|rcsb pdb:1R8P|rcsb pdb:1ZZF|rcsb pdb:2NNU|rcsb pdb:2Q79|rcsb pdb:3MI7|mint:MINT-8393762(identity)	-	comment:mint|comment:homomint	-	figure legend:f9c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2012/09/24	2014/10/16	rogid:TT4WZ7qxsOzGEppHWW+FsDiIpN49913	rogid:0/XZ8yUPpKVdUvpKjNxjHHQnmAE333760	intact-crc:10A2E8D64B004B11|rigid:KotDXKvnkOQo2XxKG+k/pvG2Lfs	false	ha tag:?-?(MINT-8393793)	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P79101	uniprotkb:P03120	intact:EBI-7894416|intact:MINT-8393774|uniprotkb:Q3MHX7|ensembl:ENSBTAP00000026303	intact:EBI-1779322|uniprotkb:Q71BI4	psi-mi:cpsf3_bovin(display_long)|uniprotkb:CPSF3(gene name)|psi-mi:CPSF3(display_short)|uniprotkb:CPSF73(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 73 kDa subunit(gene name synonym)|uniprotkb:mRNA 3'-end-processing endonuclease CPSF-73(gene name synonym)	psi-mi:ve2_hpv16(display_long)|uniprotkb:E2(gene name)|psi-mi:E2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Johansson et al. (2012)	doi:10.1038/emboj.2012.147|pubmed:22617423|imex:IM-18521|mint:MINT-8393711	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:333760(hpv16)|taxid:333760(Human papillomavirus type 16)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7895001|mint:MINT-8393796|imex:IM-18521-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_776709.1|ensembl:ENSBTAG00000019735(gene)|ensembl:ENSBTAT00000026303(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|mint:MINT-8393800(identity)	refseq:NP_041328.1|dip:DIP-44574N|mint:P03120|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006260"(DNA replication)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0044163"(host cytoskeleton)|interpro:IPR000427(E2 early regulatory protein, C-terminal)|interpro:IPR001866(E2 early regulatory protein, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033668|interpro:IPR035975|interpro:IPR036050|interpro:IPR042503|interpro:IPR042504|rcsb pdb:1BY9|rcsb pdb:1DTO|rcsb pdb:1R8P|rcsb pdb:1ZZF|rcsb pdb:2NNU|rcsb pdb:2Q79|rcsb pdb:3MI7|mint:MINT-8393798(identity)	-	comment:mint|comment:homomint	-	figure legend:f9c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2012/09/24	2014/10/16	rogid:PzGiogw7aFBVGuRecRNj0BYd2lQ9913	rogid:0/XZ8yUPpKVdUvpKjNxjHHQnmAE333760	intact-crc:C9523DD29A761803|rigid:RDgS46gPERWuvi0xD035JqMTT6Y	false	ha tag:?-?(MINT-8393801)	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)