#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q4GYY5	uniprotkb:Q57UH8	intact:EBI-895541	intact:EBI-6146607|uniprotkb:D6XLP0	psi-mi:q4gyy5_tryb2(display_long)|uniprotkb:TB927.1.2340(orf name)|uniprotkb:TB927.1.2360(orf name)|uniprotkb:TB927.1.2380(orf name)|uniprotkb:TB927.1.2400(orf name)	psi-mi:q57uh8_tryb2(display_long)|uniprotkb:Tb927.8.5060(orf name)	psi-mi:"MI:0663"(confocal microscopy)	Price et al. (2012)	pubmed:22609302|imex:IM-17357	taxid:185431(tryb2)|taxid:185431("Trypanosoma brucei brucei (strain 927/4 GUTat10.1)")	taxid:185431(tryb2)|taxid:185431("Trypanosoma brucei brucei (strain 927/4 GUTat10.1)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6146601|imex:IM-17357-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_001218934.1|refseq:XP_001218936.1|refseq:XP_001218938.1|refseq:XP_001218940.1|interpro:IPR002452(Alpha tubulin)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR000217(Tubulin)|interpro:IPR018316|interpro:IPR017975|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003924"(GTPase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0036064"(ciliary basal body)	interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|refseq:XP_847336.1|interpro:IPR027417|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005930"(axoneme)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0015631"(tubulin binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0097014"(ciliary plasm)|go:"GO:0007264"(small GTPase mediated signal transduction)	-	-	-	figure legend:Fig 1A|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:185431(tryb2)|taxid:185431("Trypanosoma brucei brucei (strain 927/4 GUTat10.1)")	-	2012/06/11	2014/10/16	rogid:2GJnWdkbDZXVDZzUuzDJyy6qHuY185431	rogid:kCmbW2RyIKaI+HOSOQVmj7Zmgss185431	intact-crc:316941362389EC6E|rigid:v8K4qdp62aFU3GBguwXaE84wYyU	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q57UH8	uniprotkb:Q38DU9	intact:EBI-6146607|uniprotkb:D6XLP0	intact:EBI-6146907	psi-mi:q57uh8_tryb2(display_long)|uniprotkb:Tb927.8.5060(orf name)	psi-mi:q38du9_tryb2(display_long)|uniprotkb:Tb09.211.2080(orf name)	psi-mi:"MI:0663"(confocal microscopy)	Price et al. (2012)	pubmed:22609302|imex:IM-17357	taxid:185431(tryb2)|taxid:185431("Trypanosoma brucei brucei (strain 927/4 GUTat10.1)")	taxid:185431(tryb2)|taxid:185431("Trypanosoma brucei brucei (strain 927/4 GUTat10.1)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6146903|imex:IM-17357-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|refseq:XP_847336.1|interpro:IPR027417|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005930"(axoneme)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0015631"(tubulin binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0097014"(ciliary plasm)|go:"GO:0007264"(small GTPase mediated signal transduction)	interpro:IPR032728|interpro:IPR036322|refseq:XP_827351.1|interpro:IPR028784|go:"GO:0005113"(patched binding)|go:"GO:0005119"(smoothened binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005930"(axoneme)|go:"GO:0006907"(pinocytosis)|go:"GO:0020018"(ciliary pocket membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0033572"(transferrin transport)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0061512"(protein localization to cilium)|go:"GO:1905515"(non-motile cilium assembly)	-	-	-	figure legend:Fig 6B|comment:ARL6 co-localises with the MYCBBS1 protein at the posterior end of the parasite.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:185431(tryb2)|taxid:185431("Trypanosoma brucei brucei (strain 927/4 GUTat10.1)")	-	2012/06/11	2014/10/16	rogid:kCmbW2RyIKaI+HOSOQVmj7Zmgss185431	rogid:9N2EyX0WAr4YWQRd2g7yaMqEwYk185431	intact-crc:944725371D177907|rigid:RNrooFVuLPDR+OrgAQAf0NDGvY0	false	-	myc tag:n-n	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
chebi:"CHEBI:17552"	chebi:"CHEBI:18420"	intact:EBI-1265684	intact:EBI-967760	psi-mi:gdp(display_short)|psi-mi:"CHEBI:17552"(display_long)	psi-mi:"magnesium(2+)"(display_short)|psi-mi:"CHEBI:18420"(display_long)	psi-mi:"MI:0051"(fluorescence technology)	Price et al. (2012)	pubmed:22609302|imex:IM-17357	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6146868|imex:IM-17357-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	-	-	-	figure legend:Fig 5B|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/06/11	2014/10/16	-	-	intact-crc:AEA2414431B989AA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:17552"	uniprotkb:Q57UH8	intact:EBI-1265684	intact:EBI-6146607|uniprotkb:D6XLP0	psi-mi:gdp(display_short)|psi-mi:"CHEBI:17552"(display_long)	psi-mi:q57uh8_tryb2(display_long)|uniprotkb:Tb927.8.5060(orf name)	psi-mi:"MI:0051"(fluorescence technology)	Price et al. (2012)	pubmed:22609302|imex:IM-17357	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:185431(tryb2)|taxid:185431("Trypanosoma brucei brucei (strain 927/4 GUTat10.1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6146868|imex:IM-17357-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|refseq:XP_847336.1|interpro:IPR027417|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005930"(axoneme)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0015631"(tubulin binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0097014"(ciliary plasm)|go:"GO:0007264"(small GTPase mediated signal transduction)	-	-	-	figure legend:Fig 5B|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/06/11	2014/10/16	-	rogid:kCmbW2RyIKaI+HOSOQVmj7Zmgss185431	intact-crc:AEA2414431B989AA	false	-	his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:32735"	uniprotkb:Q57UH8	intact:EBI-6146831	intact:EBI-6146607|uniprotkb:D6XLP0	psi-mi:guanidinium hydrochloride(display_short)|psi-mi:"CHEBI:32735"(display_long)	psi-mi:q57uh8_tryb2(display_long)|uniprotkb:Tb927.8.5060(orf name)	psi-mi:"MI:0051"(fluorescence technology)	Price et al. (2012)	pubmed:22609302|imex:IM-17357	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:185431(tryb2)|taxid:185431("Trypanosoma brucei brucei (strain 927/4 GUTat10.1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6146825|imex:IM-17357-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|refseq:XP_847336.1|interpro:IPR027417|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005930"(axoneme)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0015631"(tubulin binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0097014"(ciliary plasm)|go:"GO:0007264"(small GTPase mediated signal transduction)	-	-	-	figure legend:Fig 5A|comment:denaturation/ loss of folding -causing  an increase in tryptophan fluorescence and a red shift of the emission maximum from 350 nm to 356 nm.|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/06/11	2014/10/16	-	rogid:kCmbW2RyIKaI+HOSOQVmj7Zmgss185431	intact-crc:3DF1633860145554	false	-	his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15996"	chebi:"CHEBI:18420"	intact:EBI-989053|chebi:"CHEBI:42934"|chebi:"CHEBI:5234"|chebi:"CHEBI:13342"|chebi:"CHEBI:24451"	intact:EBI-967760	psi-mi:gtp(display_short)|psi-mi:"CHEBI:15996"(display_long)|intact:5'-GTP(synonym)|intact:GTP(synonym)|intact:Guanosine 5'-triphosphate(synonym)|intact:guanosine 5'-triphosphoric acid(synonym)|intact:guanosine triphosphate(synonym)|intact:GUANOSINE-5'-TRIPHOSPHATE(synonym)|intact:H4gtp(synonym)|intact:"guanosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:"magnesium(2+)"(display_short)|psi-mi:"CHEBI:18420"(display_long)	psi-mi:"MI:0051"(fluorescence technology)	Price et al. (2012)	pubmed:22609302|imex:IM-17357	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6146856|imex:IM-17357-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	-	author-identifiers:"InChI=1/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1/f/h14,19-20,22,24H,11H2"	-	figure legend:Fig 5B|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/06/11	2016/08/15	-	-	intact-crc:A86A0E06182C73A7	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15996"	uniprotkb:Q57UH8	intact:EBI-989053|chebi:"CHEBI:42934"|chebi:"CHEBI:5234"|chebi:"CHEBI:13342"|chebi:"CHEBI:24451"	intact:EBI-6146607|uniprotkb:D6XLP0	psi-mi:gtp(display_short)|psi-mi:"CHEBI:15996"(display_long)|intact:5'-GTP(synonym)|intact:GTP(synonym)|intact:Guanosine 5'-triphosphate(synonym)|intact:guanosine 5'-triphosphoric acid(synonym)|intact:guanosine triphosphate(synonym)|intact:GUANOSINE-5'-TRIPHOSPHATE(synonym)|intact:H4gtp(synonym)|intact:"guanosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:q57uh8_tryb2(display_long)|uniprotkb:Tb927.8.5060(orf name)	psi-mi:"MI:0051"(fluorescence technology)	Price et al. (2012)	pubmed:22609302|imex:IM-17357	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:185431(tryb2)|taxid:185431("Trypanosoma brucei brucei (strain 927/4 GUTat10.1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6146856|imex:IM-17357-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|refseq:XP_847336.1|interpro:IPR027417|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005930"(axoneme)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0015631"(tubulin binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0097014"(ciliary plasm)|go:"GO:0007264"(small GTPase mediated signal transduction)	-	author-identifiers:"InChI=1/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1/f/h14,19-20,22,24H,11H2"	-	figure legend:Fig 5B|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/06/11	2016/08/15	-	rogid:kCmbW2RyIKaI+HOSOQVmj7Zmgss185431	intact-crc:A86A0E06182C73A7	false	-	his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:17552"	chebi:"CHEBI:18420"	intact:EBI-1265684	intact:EBI-967760	psi-mi:gdp(display_short)|psi-mi:"CHEBI:17552"(display_long)	psi-mi:"magnesium(2+)"(display_short)|psi-mi:"CHEBI:18420"(display_long)	psi-mi:"MI:0051"(fluorescence technology)	Price et al. (2012)	pubmed:22609302|imex:IM-17357	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6146887|imex:IM-17357-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	-	-	-	figure legend:Fig 5C/E/G|comment:"The κdiss for N-methylanthranil acid labelled (mant)GDP was found to be 0.0076 s− 1  when displaced with unlabelled GDP and 0.0093 s− 1  when displaced with unlabelled GTP."|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:4.35x10^-6(molar)|koff:0.008(per mole per second)|koff:0.009(per mole per second)	2012/06/11	2014/10/16	-	-	intact-crc:F9F2C9BDD9341E6F	false	fluorophore:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:17552"	uniprotkb:Q57UH8	intact:EBI-1265684	intact:EBI-6146607|uniprotkb:D6XLP0	psi-mi:gdp(display_short)|psi-mi:"CHEBI:17552"(display_long)	psi-mi:q57uh8_tryb2(display_long)|uniprotkb:Tb927.8.5060(orf name)	psi-mi:"MI:0051"(fluorescence technology)	Price et al. (2012)	pubmed:22609302|imex:IM-17357	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:185431(tryb2)|taxid:185431("Trypanosoma brucei brucei (strain 927/4 GUTat10.1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6146887|imex:IM-17357-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|refseq:XP_847336.1|interpro:IPR027417|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005930"(axoneme)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0015631"(tubulin binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0097014"(ciliary plasm)|go:"GO:0007264"(small GTPase mediated signal transduction)	-	-	-	figure legend:Fig 5C/E/G|comment:"The κdiss for N-methylanthranil acid labelled (mant)GDP was found to be 0.0076 s− 1  when displaced with unlabelled GDP and 0.0093 s− 1  when displaced with unlabelled GTP."|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:4.35x10^-6(molar)|koff:0.008(per mole per second)|koff:0.009(per mole per second)	2012/06/11	2014/10/16	-	rogid:kCmbW2RyIKaI+HOSOQVmj7Zmgss185431	intact-crc:F9F2C9BDD9341E6F	false	fluorophore:?-?	his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15996"	chebi:"CHEBI:18420"	intact:EBI-989053|chebi:"CHEBI:42934"|chebi:"CHEBI:5234"|chebi:"CHEBI:13342"|chebi:"CHEBI:24451"	intact:EBI-967760	psi-mi:gtp(display_short)|psi-mi:"CHEBI:15996"(display_long)|intact:5'-GTP(synonym)|intact:GTP(synonym)|intact:Guanosine 5'-triphosphate(synonym)|intact:guanosine 5'-triphosphoric acid(synonym)|intact:guanosine triphosphate(synonym)|intact:GUANOSINE-5'-TRIPHOSPHATE(synonym)|intact:H4gtp(synonym)|intact:"guanosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:"magnesium(2+)"(display_short)|psi-mi:"CHEBI:18420"(display_long)	psi-mi:"MI:0051"(fluorescence technology)	Price et al. (2012)	pubmed:22609302|imex:IM-17357	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6146876|imex:IM-17357-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0328"(small molecule)	-	-	-	author-identifiers:"InChI=1/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1/f/h14,19-20,22,24H,11H2"	-	figure legend:Fig 5D/F/H|comment:"The κdiss for N-methylanthranil acid (mant)GTP was found to be 0.0047  s-1  when displaced with unlabelled GDP and 0.0041 s− 1  when displaced with unlabelled GTP."|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:13.71x10^-6(molar)|koff:0.004(per mole per second)|koff:0.005(per mole per second)	2012/06/11	2016/08/15	-	-	intact-crc:8CD50742975B3BF4	false	fluorophore:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
chebi:"CHEBI:15996"	uniprotkb:Q57UH8	intact:EBI-989053|chebi:"CHEBI:42934"|chebi:"CHEBI:5234"|chebi:"CHEBI:13342"|chebi:"CHEBI:24451"	intact:EBI-6146607|uniprotkb:D6XLP0	psi-mi:gtp(display_short)|psi-mi:"CHEBI:15996"(display_long)|intact:5'-GTP(synonym)|intact:GTP(synonym)|intact:Guanosine 5'-triphosphate(synonym)|intact:guanosine 5'-triphosphoric acid(synonym)|intact:guanosine triphosphate(synonym)|intact:GUANOSINE-5'-TRIPHOSPHATE(synonym)|intact:H4gtp(synonym)|intact:"guanosine 5'-(tetrahydrogen triphosphate)"(iupac name)	psi-mi:q57uh8_tryb2(display_long)|uniprotkb:Tb927.8.5060(orf name)	psi-mi:"MI:0051"(fluorescence technology)	Price et al. (2012)	pubmed:22609302|imex:IM-17357	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:185431(tryb2)|taxid:185431("Trypanosoma brucei brucei (strain 927/4 GUTat10.1)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6146876|imex:IM-17357-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|refseq:XP_847336.1|interpro:IPR027417|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005930"(axoneme)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0015631"(tubulin binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0097014"(ciliary plasm)|go:"GO:0007264"(small GTPase mediated signal transduction)	-	author-identifiers:"InChI=1/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1/f/h14,19-20,22,24H,11H2"	-	figure legend:Fig 5D/F/H|comment:"The κdiss for N-methylanthranil acid (mant)GTP was found to be 0.0047  s-1  when displaced with unlabelled GDP and 0.0041 s− 1  when displaced with unlabelled GTP."|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	kd:13.71x10^-6(molar)|koff:0.004(per mole per second)|koff:0.005(per mole per second)	2012/06/11	2016/08/15	-	rogid:kCmbW2RyIKaI+HOSOQVmj7Zmgss185431	intact-crc:8CD50742975B3BF4	false	fluorophore:?-?	his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)