#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q6VVB1 uniprotkb:Q9WUA5 intact:EBI-6426628|ensembl:ENSP00000345464|uniprotkb:Q6IMH1|uniprotkb:Q5VUK7|uniprotkb:Q3SYB1 intact:EBI-1040928|uniprotkb:Q8BY80|ensembl:ENSMUSP00000066050|uniprotkb:G5E8E2 psi-mi:nhlc1_human(display_long)|uniprotkb:NHLRC1(gene name)|psi-mi:NHLRC1(display_short)|uniprotkb:EPM2B(gene name synonym)|uniprotkb:Malin(gene name synonym)|uniprotkb:NHL repeat-containing protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NHLRC1(gene name synonym) psi-mi:epm2a_mouse(display_long)|uniprotkb:Epm2a(gene name)|psi-mi:Epm2a(display_short)|uniprotkb:Lafora PTPase(gene name synonym)|uniprotkb:Glucan phosphatase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zeng et al. (2012) pubmed:22578008|mint:MINT-8373204 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7866112|mint:MINT-8374101 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187566(gene)|ensembl:ENST00000340650(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_940988.2|mint:MINT-8374103(identity) ensembl:ENSMUSG00000055493(gene)|ensembl:ENSMUST00000069106(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006914"(autophagy)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019203"(carbohydrate phosphatase activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030425"(dendrite)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044260"(cellular macromolecule metabolic process)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|go:"GO:0046959"(habituation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:2000465"("regulation of glycogen (starch) synthase activity")|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR034831|interpro:IPR042942|go:"GO:0007399"(nervous system development)|refseq:NP_034276.2|mint:MINT-8374104(identity) - - - comment:mint|figure legend:f3a taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/05/08 2014/10/16 rogid:jLFXF8B5yGb+VWcX1MkEFOm8hUU9606 rogid:lpytge02SPNx88wHsa5gT28gOiM10090 intact-crc:D4ED99450A41552B|rigid:XHNYqdYEeXfP4IXUd+y9pAD4uOo false flag tag:?-?(MINT-8374112) ha tag:?-?(MINT-8374106)|binding-associated region:107-242(MINT-8374109) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6VVB1 uniprotkb:Q9WUA5 intact:EBI-6426628|ensembl:ENSP00000345464|uniprotkb:Q6IMH1|uniprotkb:Q5VUK7|uniprotkb:Q3SYB1 intact:EBI-1040928|uniprotkb:Q8BY80|ensembl:ENSMUSP00000066050|uniprotkb:G5E8E2 psi-mi:nhlc1_human(display_long)|uniprotkb:NHLRC1(gene name)|psi-mi:NHLRC1(display_short)|uniprotkb:EPM2B(gene name synonym)|uniprotkb:Malin(gene name synonym)|uniprotkb:NHL repeat-containing protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NHLRC1(gene name synonym) psi-mi:epm2a_mouse(display_long)|uniprotkb:Epm2a(gene name)|psi-mi:Epm2a(display_short)|uniprotkb:Lafora PTPase(gene name synonym)|uniprotkb:Glucan phosphatase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zeng et al. (2012) pubmed:22578008|mint:MINT-8373204 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7866166|mint:MINT-8374118 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187566(gene)|ensembl:ENST00000340650(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_940988.2|mint:MINT-8374120(identity) ensembl:ENSMUSG00000055493(gene)|ensembl:ENSMUST00000069106(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006914"(autophagy)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019203"(carbohydrate phosphatase activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030425"(dendrite)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044260"(cellular macromolecule metabolic process)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|go:"GO:0046959"(habituation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:2000465"("regulation of glycogen (starch) synthase activity")|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR034831|interpro:IPR042942|go:"GO:0007399"(nervous system development)|refseq:NP_034276.2|mint:MINT-8374124(identity) - - - figure legend:f3b|comment:mint taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/05/08 2014/10/16 rogid:jLFXF8B5yGb+VWcX1MkEFOm8hUU9606 rogid:lpytge02SPNx88wHsa5gT28gOiM10090 intact-crc:B4C577759CBF1E9E|rigid:XHNYqdYEeXfP4IXUd+y9pAD4uOo false flag tag:?-?(MINT-8374121)|binding-associated region:72-157(MINT-8374133) myc tag:?-?(MINT-8374127) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6VVB1 uniprotkb:Q9WUA5 intact:EBI-6426628|ensembl:ENSP00000345464|uniprotkb:Q6IMH1|uniprotkb:Q5VUK7|uniprotkb:Q3SYB1 intact:EBI-1040928|uniprotkb:Q8BY80|ensembl:ENSMUSP00000066050|uniprotkb:G5E8E2 psi-mi:nhlc1_human(display_long)|uniprotkb:NHLRC1(gene name)|psi-mi:NHLRC1(display_short)|uniprotkb:EPM2B(gene name synonym)|uniprotkb:Malin(gene name synonym)|uniprotkb:NHL repeat-containing protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NHLRC1(gene name synonym) psi-mi:epm2a_mouse(display_long)|uniprotkb:Epm2a(gene name)|psi-mi:Epm2a(display_short)|uniprotkb:Lafora PTPase(gene name synonym)|uniprotkb:Glucan phosphatase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zeng et al. (2012) pubmed:22578008|mint:MINT-8373204 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7866202|mint:MINT-8374157 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187566(gene)|ensembl:ENST00000340650(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_940988.2|mint:MINT-8374159(identity) ensembl:ENSMUSG00000055493(gene)|ensembl:ENSMUST00000069106(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006914"(autophagy)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019203"(carbohydrate phosphatase activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030425"(dendrite)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044260"(cellular macromolecule metabolic process)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|go:"GO:0046959"(habituation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:2000465"("regulation of glycogen (starch) synthase activity")|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR034831|interpro:IPR042942|go:"GO:0007399"(nervous system development)|refseq:NP_034276.2|mint:MINT-8374165(identity) - - - figure legend:f3c|comment:mint taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/05/08 2014/10/16 rogid:jLFXF8B5yGb+VWcX1MkEFOm8hUU9606 rogid:lpytge02SPNx88wHsa5gT28gOiM10090 intact-crc:67ACC7AC102A075C|rigid:XHNYqdYEeXfP4IXUd+y9pAD4uOo false mutation decreasing interaction:26-26(MINT-8374162)|v5 tag:?-?(MINT-8374160) flag tag:?-?(MINT-8374166) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6VVB1 uniprotkb:Q9WUA5 intact:EBI-6426628|ensembl:ENSP00000345464|uniprotkb:Q6IMH1|uniprotkb:Q5VUK7|uniprotkb:Q3SYB1 intact:EBI-1040928|uniprotkb:Q8BY80|ensembl:ENSMUSP00000066050|uniprotkb:G5E8E2 psi-mi:nhlc1_human(display_long)|uniprotkb:NHLRC1(gene name)|psi-mi:NHLRC1(display_short)|uniprotkb:EPM2B(gene name synonym)|uniprotkb:Malin(gene name synonym)|uniprotkb:NHL repeat-containing protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NHLRC1(gene name synonym) psi-mi:epm2a_mouse(display_long)|uniprotkb:Epm2a(gene name)|psi-mi:Epm2a(display_short)|uniprotkb:Lafora PTPase(gene name synonym)|uniprotkb:Glucan phosphatase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zeng et al. (2012) pubmed:22578008|mint:MINT-8373204 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7866222|mint:MINT-8374170 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187566(gene)|ensembl:ENST00000340650(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_940988.2|mint:MINT-8374172(identity) ensembl:ENSMUSG00000055493(gene)|ensembl:ENSMUST00000069106(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006914"(autophagy)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019203"(carbohydrate phosphatase activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030425"(dendrite)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044260"(cellular macromolecule metabolic process)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|go:"GO:0046959"(habituation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:2000465"("regulation of glycogen (starch) synthase activity")|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR034831|interpro:IPR042942|go:"GO:0007399"(nervous system development)|refseq:NP_034276.2|mint:MINT-8374178(identity) - - - figure legend:f3c|comment:mint taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/05/08 2014/10/16 rogid:jLFXF8B5yGb+VWcX1MkEFOm8hUU9606 rogid:lpytge02SPNx88wHsa5gT28gOiM10090 intact-crc:43B3F3F3BEC728BC|rigid:XHNYqdYEeXfP4IXUd+y9pAD4uOo false v5 tag:?-?(MINT-8374175)|mutation decreasing interaction:87-87(MINT-8374173) flag tag:?-?(MINT-8374179) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6VVB1 uniprotkb:Q9WUA5 intact:EBI-6426628|ensembl:ENSP00000345464|uniprotkb:Q6IMH1|uniprotkb:Q5VUK7|uniprotkb:Q3SYB1 intact:EBI-1040928|uniprotkb:Q8BY80|ensembl:ENSMUSP00000066050|uniprotkb:G5E8E2 psi-mi:nhlc1_human(display_long)|uniprotkb:NHLRC1(gene name)|psi-mi:NHLRC1(display_short)|uniprotkb:EPM2B(gene name synonym)|uniprotkb:Malin(gene name synonym)|uniprotkb:NHL repeat-containing protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NHLRC1(gene name synonym) psi-mi:epm2a_mouse(display_long)|uniprotkb:Epm2a(gene name)|psi-mi:Epm2a(display_short)|uniprotkb:Lafora PTPase(gene name synonym)|uniprotkb:Glucan phosphatase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zeng et al. (2012) pubmed:22578008|mint:MINT-8373204 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7866363|mint:MINT-8374198 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187566(gene)|ensembl:ENST00000340650(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_940988.2|mint:MINT-8374200(identity) ensembl:ENSMUSG00000055493(gene)|ensembl:ENSMUST00000069106(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006914"(autophagy)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019203"(carbohydrate phosphatase activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030425"(dendrite)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044260"(cellular macromolecule metabolic process)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|go:"GO:0046959"(habituation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:2000465"("regulation of glycogen (starch) synthase activity")|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR034831|interpro:IPR042942|go:"GO:0007399"(nervous system development)|refseq:NP_034276.2|mint:MINT-8374206(identity) - - - figure legend:f3c|comment:mint taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/05/08 2014/10/16 rogid:jLFXF8B5yGb+VWcX1MkEFOm8hUU9606 rogid:lpytge02SPNx88wHsa5gT28gOiM10090 intact-crc:52C4AA178520CDBD|rigid:XHNYqdYEeXfP4IXUd+y9pAD4uOo false mutation disrupting interaction:198-198(MINT-8374201)|v5 tag:?-?(MINT-8374203) flag tag:?-?(MINT-8374207) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6VVB1 uniprotkb:Q9WUA5 intact:EBI-6426628|ensembl:ENSP00000345464|uniprotkb:Q6IMH1|uniprotkb:Q5VUK7|uniprotkb:Q3SYB1 intact:EBI-1040928|uniprotkb:Q8BY80|ensembl:ENSMUSP00000066050|uniprotkb:G5E8E2 psi-mi:nhlc1_human(display_long)|uniprotkb:NHLRC1(gene name)|psi-mi:NHLRC1(display_short)|uniprotkb:EPM2B(gene name synonym)|uniprotkb:Malin(gene name synonym)|uniprotkb:NHL repeat-containing protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NHLRC1(gene name synonym) psi-mi:epm2a_mouse(display_long)|uniprotkb:Epm2a(gene name)|psi-mi:Epm2a(display_short)|uniprotkb:Lafora PTPase(gene name synonym)|uniprotkb:Glucan phosphatase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zeng et al. (2012) pubmed:22578008|mint:MINT-8373204 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7866343|mint:MINT-8374185 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187566(gene)|ensembl:ENST00000340650(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_940988.2|mint:MINT-8374187(identity) ensembl:ENSMUSG00000055493(gene)|ensembl:ENSMUST00000069106(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006914"(autophagy)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019203"(carbohydrate phosphatase activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030425"(dendrite)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044260"(cellular macromolecule metabolic process)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|go:"GO:0046959"(habituation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:2000465"("regulation of glycogen (starch) synthase activity")|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR034831|interpro:IPR042942|go:"GO:0007399"(nervous system development)|refseq:NP_034276.2|mint:MINT-8374193(identity) - - - figure legend:f3c|comment:mint taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/05/08 2014/10/16 rogid:jLFXF8B5yGb+VWcX1MkEFOm8hUU9606 rogid:lpytge02SPNx88wHsa5gT28gOiM10090 intact-crc:50A8916A1E81E55A|rigid:XHNYqdYEeXfP4IXUd+y9pAD4uOo false v5 tag:?-?(MINT-8374188)|mutation disrupting interaction:146-146(MINT-8374190) flag tag:?-?(MINT-8374194) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6VVB1 uniprotkb:Q9WUA5 intact:EBI-6426628|ensembl:ENSP00000345464|uniprotkb:Q6IMH1|uniprotkb:Q5VUK7|uniprotkb:Q3SYB1 intact:EBI-1040928|uniprotkb:Q8BY80|ensembl:ENSMUSP00000066050|uniprotkb:G5E8E2 psi-mi:nhlc1_human(display_long)|uniprotkb:NHLRC1(gene name)|psi-mi:NHLRC1(display_short)|uniprotkb:EPM2B(gene name synonym)|uniprotkb:Malin(gene name synonym)|uniprotkb:NHL repeat-containing protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NHLRC1(gene name synonym) psi-mi:epm2a_mouse(display_long)|uniprotkb:Epm2a(gene name)|psi-mi:Epm2a(display_short)|uniprotkb:Lafora PTPase(gene name synonym)|uniprotkb:Glucan phosphatase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zeng et al. (2012) pubmed:22578008|mint:MINT-8373204 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7866446|mint:MINT-8374243 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187566(gene)|ensembl:ENST00000340650(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_940988.2|mint:MINT-8374245(identity) ensembl:ENSMUSG00000055493(gene)|ensembl:ENSMUST00000069106(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006914"(autophagy)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019203"(carbohydrate phosphatase activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030425"(dendrite)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044260"(cellular macromolecule metabolic process)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|go:"GO:0046959"(habituation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:2000465"("regulation of glycogen (starch) synthase activity")|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR034831|interpro:IPR042942|go:"GO:0007399"(nervous system development)|refseq:NP_034276.2|mint:MINT-8374251(identity) - - - figure legend:f3c|comment:mint taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/05/08 2014/10/16 rogid:jLFXF8B5yGb+VWcX1MkEFOm8hUU9606 rogid:lpytge02SPNx88wHsa5gT28gOiM10090 intact-crc:00D05C2D38080737|rigid:XHNYqdYEeXfP4IXUd+y9pAD4uOo false v5 tag:?-?(MINT-8374246)|mutation disrupting interaction:264-264(MINT-8374248) flag tag:?-?(MINT-8374252) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6VVB1 uniprotkb:Q9WUA5 intact:EBI-6426628|ensembl:ENSP00000345464|uniprotkb:Q6IMH1|uniprotkb:Q5VUK7|uniprotkb:Q3SYB1 intact:EBI-1040928|uniprotkb:Q8BY80|ensembl:ENSMUSP00000066050|uniprotkb:G5E8E2 psi-mi:nhlc1_human(display_long)|uniprotkb:NHLRC1(gene name)|psi-mi:NHLRC1(display_short)|uniprotkb:EPM2B(gene name synonym)|uniprotkb:Malin(gene name synonym)|uniprotkb:NHL repeat-containing protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NHLRC1(gene name synonym) psi-mi:epm2a_mouse(display_long)|uniprotkb:Epm2a(gene name)|psi-mi:Epm2a(display_short)|uniprotkb:Lafora PTPase(gene name synonym)|uniprotkb:Glucan phosphatase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zeng et al. (2012) pubmed:22578008|mint:MINT-8373204 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7866383|mint:MINT-8374228 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187566(gene)|ensembl:ENST00000340650(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_940988.2|mint:MINT-8374230(identity) ensembl:ENSMUSG00000055493(gene)|ensembl:ENSMUST00000069106(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006914"(autophagy)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019203"(carbohydrate phosphatase activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030425"(dendrite)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044260"(cellular macromolecule metabolic process)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|go:"GO:0046959"(habituation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:2000465"("regulation of glycogen (starch) synthase activity")|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR034831|interpro:IPR042942|go:"GO:0007399"(nervous system development)|refseq:NP_034276.2|mint:MINT-8374236(identity) - - - figure legend:f3c|comment:mint taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/05/08 2014/10/16 rogid:jLFXF8B5yGb+VWcX1MkEFOm8hUU9606 rogid:lpytge02SPNx88wHsa5gT28gOiM10090 intact-crc:8A0A85D5A094CF99|rigid:XHNYqdYEeXfP4IXUd+y9pAD4uOo false mutation disrupting interaction:233-233(MINT-8374231)|v5 tag:?-?(MINT-8374233) flag tag:?-?(MINT-8374237) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6VVB1 uniprotkb:Q9WUA5 intact:EBI-6426628|ensembl:ENSP00000345464|uniprotkb:Q6IMH1|uniprotkb:Q5VUK7|uniprotkb:Q3SYB1 intact:EBI-1040928|uniprotkb:Q8BY80|ensembl:ENSMUSP00000066050|uniprotkb:G5E8E2 psi-mi:nhlc1_human(display_long)|uniprotkb:NHLRC1(gene name)|psi-mi:NHLRC1(display_short)|uniprotkb:EPM2B(gene name synonym)|uniprotkb:Malin(gene name synonym)|uniprotkb:NHL repeat-containing protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NHLRC1(gene name synonym) psi-mi:epm2a_mouse(display_long)|uniprotkb:Epm2a(gene name)|psi-mi:Epm2a(display_short)|uniprotkb:Lafora PTPase(gene name synonym)|uniprotkb:Glucan phosphatase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zeng et al. (2012) pubmed:22578008|mint:MINT-8373204 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7866483|mint:MINT-8374258 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187566(gene)|ensembl:ENST00000340650(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_940988.2|mint:MINT-8374260(identity) ensembl:ENSMUSG00000055493(gene)|ensembl:ENSMUST00000069106(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006914"(autophagy)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019203"(carbohydrate phosphatase activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030425"(dendrite)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044260"(cellular macromolecule metabolic process)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|go:"GO:0046959"(habituation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:2000465"("regulation of glycogen (starch) synthase activity")|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR034831|interpro:IPR042942|go:"GO:0007399"(nervous system development)|refseq:NP_034276.2|mint:MINT-8374266(identity) - - - figure legend:f3c|comment:mint taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/05/08 2014/10/16 rogid:jLFXF8B5yGb+VWcX1MkEFOm8hUU9606 rogid:lpytge02SPNx88wHsa5gT28gOiM10090 intact-crc:38D8F06116AEE151|rigid:XHNYqdYEeXfP4IXUd+y9pAD4uOo false v5 tag:?-?(MINT-8374263)|mutation disrupting interaction:280-280(MINT-8374261) flag tag:?-?(MINT-8374267) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6VVB1 uniprotkb:Q9WUA5 intact:EBI-6426628|ensembl:ENSP00000345464|uniprotkb:Q6IMH1|uniprotkb:Q5VUK7|uniprotkb:Q3SYB1 intact:EBI-1040928|uniprotkb:Q8BY80|ensembl:ENSMUSP00000066050|uniprotkb:G5E8E2 psi-mi:nhlc1_human(display_long)|uniprotkb:NHLRC1(gene name)|psi-mi:NHLRC1(display_short)|uniprotkb:EPM2B(gene name synonym)|uniprotkb:Malin(gene name synonym)|uniprotkb:NHL repeat-containing protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NHLRC1(gene name synonym) psi-mi:epm2a_mouse(display_long)|uniprotkb:Epm2a(gene name)|psi-mi:Epm2a(display_short)|uniprotkb:Lafora PTPase(gene name synonym)|uniprotkb:Glucan phosphatase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zeng et al. (2012) pubmed:22578008|mint:MINT-8373204 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7866575|mint:MINT-8374288 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187566(gene)|ensembl:ENST00000340650(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_940988.2|mint:MINT-8374290(identity) ensembl:ENSMUSG00000055493(gene)|ensembl:ENSMUST00000069106(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006914"(autophagy)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019203"(carbohydrate phosphatase activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030425"(dendrite)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044260"(cellular macromolecule metabolic process)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|go:"GO:0046959"(habituation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:2000465"("regulation of glycogen (starch) synthase activity")|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR034831|interpro:IPR042942|go:"GO:0007399"(nervous system development)|refseq:NP_034276.2|mint:MINT-8374296(identity) - - - figure legend:f3c|comment:mint taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/05/08 2014/10/16 rogid:jLFXF8B5yGb+VWcX1MkEFOm8hUU9606 rogid:lpytge02SPNx88wHsa5gT28gOiM10090 intact-crc:7FDB5E29E559DADA|rigid:XHNYqdYEeXfP4IXUd+y9pAD4uOo false v5 tag:?-?(MINT-8374293)|mutation decreasing interaction:308-308(MINT-8374291) flag tag:?-?(MINT-8374297) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6VVB1 uniprotkb:Q9WUA5 intact:EBI-6426628|ensembl:ENSP00000345464|uniprotkb:Q6IMH1|uniprotkb:Q5VUK7|uniprotkb:Q3SYB1 intact:EBI-1040928|uniprotkb:Q8BY80|ensembl:ENSMUSP00000066050|uniprotkb:G5E8E2 psi-mi:nhlc1_human(display_long)|uniprotkb:NHLRC1(gene name)|psi-mi:NHLRC1(display_short)|uniprotkb:EPM2B(gene name synonym)|uniprotkb:Malin(gene name synonym)|uniprotkb:NHL repeat-containing protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NHLRC1(gene name synonym) psi-mi:epm2a_mouse(display_long)|uniprotkb:Epm2a(gene name)|psi-mi:Epm2a(display_short)|uniprotkb:Lafora PTPase(gene name synonym)|uniprotkb:Glucan phosphatase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zeng et al. (2012) pubmed:22578008|mint:MINT-8373204 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7866529|mint:MINT-8374273 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187566(gene)|ensembl:ENST00000340650(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_940988.2|mint:MINT-8374275(identity) ensembl:ENSMUSG00000055493(gene)|ensembl:ENSMUST00000069106(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006914"(autophagy)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019203"(carbohydrate phosphatase activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030425"(dendrite)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044260"(cellular macromolecule metabolic process)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|go:"GO:0046959"(habituation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:2000465"("regulation of glycogen (starch) synthase activity")|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR034831|interpro:IPR042942|go:"GO:0007399"(nervous system development)|refseq:NP_034276.2|mint:MINT-8374281(identity) - - - figure legend:f3c|comment:mint taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/05/08 2014/10/16 rogid:jLFXF8B5yGb+VWcX1MkEFOm8hUU9606 rogid:lpytge02SPNx88wHsa5gT28gOiM10090 intact-crc:FB71FA29AFBD3A74|rigid:XHNYqdYEeXfP4IXUd+y9pAD4uOo false mutation decreasing interaction:302-302(MINT-8374278)|v5 tag:?-?(MINT-8374276) flag tag:?-?(MINT-8374282) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Z1E4 uniprotkb:Q9WUA5 intact:EBI-1152696|uniprotkb:P54859|uniprotkb:Q3TBN4|uniprotkb:Q8BQG4|uniprotkb:Q8VEB0|ensembl:ENSMUSP00000003964 intact:EBI-1040928|uniprotkb:Q8BY80|ensembl:ENSMUSP00000066050|uniprotkb:G5E8E2 psi-mi:gys1_mouse(display_long)|uniprotkb:Gys1(gene name)|psi-mi:Gys1(display_short)|uniprotkb:Gys(gene name synonym)|uniprotkb:Gys3(gene name synonym) psi-mi:epm2a_mouse(display_long)|uniprotkb:Epm2a(gene name)|psi-mi:Epm2a(display_short)|uniprotkb:Lafora PTPase(gene name synonym)|uniprotkb:Glucan phosphatase(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Zeng et al. (2012) pubmed:22578008|mint:MINT-8373204 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7866670|mint:MINT-8374306 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003865(gene)|ensembl:ENSMUST00000003964(transcript)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0005536"(glucose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0007507"(heart development)|go:"GO:0016234"(inclusion body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0061547"(glycogen synthase activity, transferring glucose-1-phosphate)|interpro:IPR008631(Glycogen synthase)|mint:Q9Z1E4|reactome:R-MMU-3322077|refseq:NP_109603.2|mint:MINT-8374308(identity) ensembl:ENSMUSG00000055493(gene)|ensembl:ENSMUST00000069106(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006914"(autophagy)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019203"(carbohydrate phosphatase activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030425"(dendrite)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044260"(cellular macromolecule metabolic process)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|go:"GO:0046959"(habituation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:2000465"("regulation of glycogen (starch) synthase activity")|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR034831|interpro:IPR042942|go:"GO:0007399"(nervous system development)|refseq:NP_034276.2|mint:MINT-8374311(identity) go:"GO:0042587"(glycogen granule) - - figure legend:f4a|comment:mint taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/05/08 2014/10/16 rogid:xyxKh8kTFhokzDMbxghiowpjfyU10090 rogid:lpytge02SPNx88wHsa5gT28gOiM10090 intact-crc:46F1BE34968E4082|rigid:Dc8sGumZrtIiqfLH31h9Ww+0fic false flag tag:?-?(MINT-8374312) mutation increasing interaction:265-265(MINT-8374319)|myc tag:?-?(MINT-8374316) - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q6VVB1 uniprotkb:Q9Z1E4 intact:EBI-6426628|ensembl:ENSP00000345464|uniprotkb:Q6IMH1|uniprotkb:Q5VUK7|uniprotkb:Q3SYB1 intact:EBI-1152696|uniprotkb:P54859|uniprotkb:Q3TBN4|uniprotkb:Q8BQG4|uniprotkb:Q8VEB0|ensembl:ENSMUSP00000003964 psi-mi:nhlc1_human(display_long)|uniprotkb:NHLRC1(gene name)|psi-mi:NHLRC1(display_short)|uniprotkb:EPM2B(gene name synonym)|uniprotkb:Malin(gene name synonym)|uniprotkb:NHL repeat-containing protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NHLRC1(gene name synonym) psi-mi:gys1_mouse(display_long)|uniprotkb:Gys1(gene name)|psi-mi:Gys1(display_short)|uniprotkb:Gys(gene name synonym)|uniprotkb:Gys3(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Zeng et al. (2012) pubmed:22578008|mint:MINT-8373204 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7866697|mint:MINT-8374326 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187566(gene)|ensembl:ENST00000340650(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_940988.2|mint:MINT-8374328(identity) ensembl:ENSMUSG00000003865(gene)|ensembl:ENSMUST00000003964(transcript)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0005536"(glucose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0007507"(heart development)|go:"GO:0016234"(inclusion body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0061547"(glycogen synthase activity, transferring glucose-1-phosphate)|interpro:IPR008631(Glycogen synthase)|mint:Q9Z1E4|reactome:R-MMU-3322077|refseq:NP_109603.2|mint:MINT-8374330(identity) - - - figure legend:f4b|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/08 2014/10/16 rogid:jLFXF8B5yGb+VWcX1MkEFOm8hUU9606 rogid:xyxKh8kTFhokzDMbxghiowpjfyU10090 intact-crc:96324C51B72D7ED6|rigid:YqHExEkp5+KRA0HSrmzBcchDn+A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6VVB1 uniprotkb:Q9WUA5 intact:EBI-6426628|ensembl:ENSP00000345464|uniprotkb:Q6IMH1|uniprotkb:Q5VUK7|uniprotkb:Q3SYB1 intact:EBI-1040928|uniprotkb:Q8BY80|ensembl:ENSMUSP00000066050|uniprotkb:G5E8E2 psi-mi:nhlc1_human(display_long)|uniprotkb:NHLRC1(gene name)|psi-mi:NHLRC1(display_short)|uniprotkb:EPM2B(gene name synonym)|uniprotkb:Malin(gene name synonym)|uniprotkb:NHL repeat-containing protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NHLRC1(gene name synonym) psi-mi:epm2a_mouse(display_long)|uniprotkb:Epm2a(gene name)|psi-mi:Epm2a(display_short)|uniprotkb:Lafora PTPase(gene name synonym)|uniprotkb:Glucan phosphatase(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Zeng et al. (2012) pubmed:22578008|mint:MINT-8373204 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7866697|mint:MINT-8374326 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187566(gene)|ensembl:ENST00000340650(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|reactome:R-HSA-3322077|reactome:R-HSA-3785653|refseq:NP_940988.2|mint:MINT-8374328(identity) ensembl:ENSMUSG00000055493(gene)|ensembl:ENSMUST00000069106(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006914"(autophagy)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019203"(carbohydrate phosphatase activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030425"(dendrite)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035305"(negative regulation of dephosphorylation)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044260"(cellular macromolecule metabolic process)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0046838"(phosphorylated carbohydrate dephosphorylation)|go:"GO:0046959"(habituation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:2000465"("regulation of glycogen (starch) synthase activity")|go:"GO:2001069"(glycogen binding)|go:"GO:2001070"(starch binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR002044(Glycoside hydrolase, carbohydrate-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013784(Carbohydrate-binding-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR034831|interpro:IPR042942|go:"GO:0007399"(nervous system development)|refseq:NP_034276.2|mint:MINT-8374329(identity) - - - figure legend:f4b|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/05/08 2014/10/16 rogid:jLFXF8B5yGb+VWcX1MkEFOm8hUU9606 rogid:lpytge02SPNx88wHsa5gT28gOiM10090 intact-crc:96324C51B72D7ED6|rigid:YqHExEkp5+KRA0HSrmzBcchDn+A false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)