#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P61981 uniprotkb:Q15831 intact:EBI-359832|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q6FH52|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSP00000306330 intact:EBI-306838|ensembl:ENSP00000324856|uniprotkb:E7EW76|uniprotkb:B2RBX7 psi-mi:1433g_human(display_long)|uniprotkb:YWHAG(gene name)|psi-mi:YWHAG(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:stk11_human(display_long)|uniprotkb:STK11(gene name)|psi-mi:STK11(display_short)|uniprotkb:LKB1(gene name synonym)|uniprotkb:PJS(gene name synonym)|uniprotkb:Liver kinase B1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-19(gene name synonym) psi-mi:"MI:0096"(pull down) Bai et al. (2012) pubmed:22575644|mint:MINT-8329523 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7852229|mint:MINT-8329634 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036611.2|ensembl:ENSG00000170027(gene)|ensembl:ENST00000307630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006605"(protein targeting)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61981|rcsb pdb:2B05|rcsb pdb:3UZD|rcsb pdb:4E2E|rcsb pdb:4J6S|rcsb pdb:4O46|rcsb pdb:5D3E|rcsb pdb:6A5S|rcsb pdb:6BYJ|rcsb pdb:6BYL|rcsb pdb:6BZD|rcsb pdb:6FEL|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y4K|rcsb pdb:6Y6B|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-9614399|dip:DIP-33406N|mint:MINT-8329637(identity) ensembl:ENSG00000118046(gene)|ensembl:ENST00000326873(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001944"(vasculature development)|go:"GO:0002039"(p53 binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030275"(LRR domain binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043276"(anoikis)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0051645"(Golgi localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097484"(dendrite extension)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901610"(positive regulation of vesicle transport along microtubule)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039154|rcsb pdb:2WTK|rcsb pdb:4ZDR|rcsb pdb:5WXN|reactome:R-HSA-163680|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-380972|reactome:R-HSA-6804756|reactome:R-HSA-9614657|refseq:NP_000446.1|refseq:XP_005259675.1|dip:DIP-31317N|mint:MINT-8329636(identity) - - - comment:homomint|comment:domino|comment:mint|figure legend:f1b f2b taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/03/09 2014/10/16 rogid:u1cd71h0RPgTOEMrQVhOelsxWnM9606 rogid:zBd9tuO3eqwjdeyPXdKKe6sHPHY9606 intact-crc:163047F31C64F38A|rigid:B9A5kCZZyHA0Uax+dW2LF+A1Fic false his tag:?-?(MINT-8329646) mutation disrupting interaction:336-336(MINT-8329642)|glutathione s tranferase tag:?-?(MINT-8329639) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q04917 uniprotkb:Q15831 intact:EBI-306940|ensembl:ENSP00000248975|intact:EBI-11759595 intact:EBI-306838|ensembl:ENSP00000324856|uniprotkb:E7EW76|uniprotkb:B2RBX7 psi-mi:1433f_human(display_long)|uniprotkb:YWHAH(gene name)|psi-mi:YWHAH(display_short)|uniprotkb:YWHA1(gene name synonym)|uniprotkb:Protein AS1(gene name synonym) psi-mi:stk11_human(display_long)|uniprotkb:STK11(gene name)|psi-mi:STK11(display_short)|uniprotkb:LKB1(gene name synonym)|uniprotkb:PJS(gene name synonym)|uniprotkb:Liver kinase B1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-19(gene name synonym) psi-mi:"MI:0096"(pull down) Bai et al. (2012) pubmed:22575644|mint:MINT-8329523 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7852268|mint:MINT-8329650 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:Q04917|rcsb pdb:2C63|rcsb pdb:2C74|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|ensembl:ENSG00000128245(gene)|ensembl:ENST00000248975(transcript)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003779"(actin binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_003396.1|dip:DIP-27566N|mint:MINT-8329658(identity) ensembl:ENSG00000118046(gene)|ensembl:ENST00000326873(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001944"(vasculature development)|go:"GO:0002039"(p53 binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030275"(LRR domain binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043276"(anoikis)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0051645"(Golgi localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097484"(dendrite extension)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901610"(positive regulation of vesicle transport along microtubule)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039154|rcsb pdb:2WTK|rcsb pdb:4ZDR|rcsb pdb:5WXN|reactome:R-HSA-163680|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-380972|reactome:R-HSA-6804756|reactome:R-HSA-9614657|refseq:NP_000446.1|refseq:XP_005259675.1|dip:DIP-31317N|mint:MINT-8329652(identity) - - - comment:homomint|comment:domino|comment:mint|figure legend:f1b f2b taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/03/09 2014/10/16 rogid:VhFYPSsW3IRC388FTlmwwN37HnU9606 rogid:zBd9tuO3eqwjdeyPXdKKe6sHPHY9606 intact-crc:833211248EE73E48|rigid:RwQT8iZe0pE77VUmzX7KCSx8H18 false his tag:?-?(MINT-8329659) glutathione s tranferase tag:?-?(MINT-8329655)|mutation disrupting interaction:336-336(MINT-8329653) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q3YBA8 uniprotkb:Q15831 intact:EBI-7852331|intact:MINT-1957887 intact:EBI-306838|ensembl:ENSP00000324856|uniprotkb:E7EW76|uniprotkb:B2RBX7 psi-mi:q3yba8_human(display_long) psi-mi:stk11_human(display_long)|uniprotkb:STK11(gene name)|psi-mi:STK11(display_short)|uniprotkb:LKB1(gene name synonym)|uniprotkb:PJS(gene name synonym)|uniprotkb:Liver kinase B1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-19(gene name synonym) psi-mi:"MI:0096"(pull down) Bai et al. (2012) pubmed:22575644|mint:MINT-8329523 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7852325|mint:MINT-8329664 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000308(14-3-3 protein)|mint:Q3YBA8|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:MINT-8329672(identity) ensembl:ENSG00000118046(gene)|ensembl:ENST00000326873(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001944"(vasculature development)|go:"GO:0002039"(p53 binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030275"(LRR domain binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043276"(anoikis)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0051645"(Golgi localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097484"(dendrite extension)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901610"(positive regulation of vesicle transport along microtubule)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039154|rcsb pdb:2WTK|rcsb pdb:4ZDR|rcsb pdb:5WXN|reactome:R-HSA-163680|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-380972|reactome:R-HSA-6804756|reactome:R-HSA-9614657|refseq:NP_000446.1|refseq:XP_005259675.1|dip:DIP-31317N|mint:MINT-8329666(identity) - comment:mint|comment:homomint - comment:homomint|comment:domino|comment:mint|figure legend:f1b f2b taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/03/09 2014/10/16 rogid:DEBDUkJS35MS6W/Fm3ccbMKrFo49606 rogid:zBd9tuO3eqwjdeyPXdKKe6sHPHY9606 intact-crc:0AEA131FC6D15AB6|rigid:1VUmTqyuj/TiUs5cnkHLm/eKpU4 false his tag:?-?(MINT-8329673) glutathione s tranferase tag:?-?(MINT-8329667)|mutation disrupting interaction:336-336(MINT-8329669) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q15831 uniprotkb:P63104 intact:EBI-306838|ensembl:ENSP00000324856|uniprotkb:E7EW76|uniprotkb:B2RBX7 intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465 psi-mi:stk11_human(display_long)|uniprotkb:STK11(gene name)|psi-mi:STK11(display_short)|uniprotkb:LKB1(gene name synonym)|uniprotkb:PJS(gene name synonym)|uniprotkb:Liver kinase B1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-19(gene name synonym) psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Bai et al. (2012) pubmed:22575644|mint:MINT-8329523 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7852377|mint:MINT-8329678 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000118046(gene)|ensembl:ENST00000326873(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001944"(vasculature development)|go:"GO:0002039"(p53 binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030275"(LRR domain binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043276"(anoikis)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0051645"(Golgi localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097484"(dendrite extension)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901610"(positive regulation of vesicle transport along microtubule)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039154|rcsb pdb:2WTK|rcsb pdb:4ZDR|rcsb pdb:5WXN|reactome:R-HSA-163680|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-380972|reactome:R-HSA-6804756|reactome:R-HSA-9614657|refseq:NP_000446.1|refseq:XP_005259675.1|dip:DIP-31317N|mint:MINT-8329680(identity) ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N|mint:MINT-8329686(identity) - - - comment:homomint|comment:domino|comment:mint|figure legend:f1b f2b taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/03/09 2014/10/16 rogid:zBd9tuO3eqwjdeyPXdKKe6sHPHY9606 rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606 intact-crc:2C738B7A22145C72|rigid:VzWWh4pZDLitf2mnHf6eRZ65R2g false glutathione s tranferase tag:?-?(MINT-8329683)|mutation disrupting interaction:336-336(MINT-8329681) his tag:?-?(MINT-8329687) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P63104 uniprotkb:Q15831 intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465 intact:EBI-306838|ensembl:ENSP00000324856|uniprotkb:E7EW76|uniprotkb:B2RBX7 psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:stk11_human(display_long)|uniprotkb:STK11(gene name)|psi-mi:STK11(display_short)|uniprotkb:LKB1(gene name synonym)|uniprotkb:PJS(gene name synonym)|uniprotkb:Liver kinase B1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-19(gene name synonym) psi-mi:"MI:0096"(pull down) Bai et al. (2012) pubmed:22575644|mint:MINT-8329523 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7852455|mint:MINT-8329695 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N|mint:MINT-8329703(identity) ensembl:ENSG00000118046(gene)|ensembl:ENST00000326873(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001944"(vasculature development)|go:"GO:0002039"(p53 binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030275"(LRR domain binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043276"(anoikis)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0051645"(Golgi localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097484"(dendrite extension)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901610"(positive regulation of vesicle transport along microtubule)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039154|rcsb pdb:2WTK|rcsb pdb:4ZDR|rcsb pdb:5WXN|reactome:R-HSA-163680|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-380972|reactome:R-HSA-6804756|reactome:R-HSA-9614657|refseq:NP_000446.1|refseq:XP_005259675.1|dip:DIP-31317N|mint:MINT-8329697(identity) - - - figure legend:f6b|comment:homomint|comment:domino|comment:mint taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/03/09 2014/10/16 rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606 rogid:zBd9tuO3eqwjdeyPXdKKe6sHPHY9606 intact-crc:3012062530724504|rigid:VzWWh4pZDLitf2mnHf6eRZ65R2g false his tag:?-?(MINT-8329704) glutathione s tranferase tag:?-?(MINT-8329698)|mutation disrupting interaction:336-336(MINT-8329700) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q15831 uniprotkb:P63104 intact:EBI-306838|ensembl:ENSP00000324856|uniprotkb:E7EW76|uniprotkb:B2RBX7 intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465 psi-mi:stk11_human(display_long)|uniprotkb:STK11(gene name)|psi-mi:STK11(display_short)|uniprotkb:LKB1(gene name synonym)|uniprotkb:PJS(gene name synonym)|uniprotkb:Liver kinase B1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-19(gene name synonym) psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Bai et al. (2012) pubmed:22575644|mint:MINT-8329523 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7852485|mint:MINT-8329714 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000118046(gene)|ensembl:ENST00000326873(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001944"(vasculature development)|go:"GO:0002039"(p53 binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030275"(LRR domain binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043276"(anoikis)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0051645"(Golgi localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097484"(dendrite extension)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901610"(positive regulation of vesicle transport along microtubule)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039154|rcsb pdb:2WTK|rcsb pdb:4ZDR|rcsb pdb:5WXN|reactome:R-HSA-163680|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-380972|reactome:R-HSA-6804756|reactome:R-HSA-9614657|refseq:NP_000446.1|refseq:XP_005259675.1|dip:DIP-31317N|mint:MINT-8329716(identity) ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N|mint:MINT-8329722(identity) - - - figure legend:f2c|comment:homomint|comment:domino|comment:mint taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2012/03/09 2014/10/16 rogid:zBd9tuO3eqwjdeyPXdKKe6sHPHY9606 rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606 intact-crc:810CA226F402F9F3|rigid:VzWWh4pZDLitf2mnHf6eRZ65R2g false glutathione s tranferase tag:?-?(MINT-8329719)|mutation disrupting interaction:336-336(MINT-8329717) his tag:?-?(MINT-8329723) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q15831 uniprotkb:P63104 intact:EBI-306838|ensembl:ENSP00000324856|uniprotkb:E7EW76|uniprotkb:B2RBX7 intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465 psi-mi:stk11_human(display_long)|uniprotkb:STK11(gene name)|psi-mi:STK11(display_short)|uniprotkb:LKB1(gene name synonym)|uniprotkb:PJS(gene name synonym)|uniprotkb:Liver kinase B1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-19(gene name synonym) psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Bai et al. (2012) pubmed:22575644|mint:MINT-8329523 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7852524|mint:MINT-8329731 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000118046(gene)|ensembl:ENST00000326873(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001944"(vasculature development)|go:"GO:0002039"(p53 binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030275"(LRR domain binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043276"(anoikis)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0051645"(Golgi localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097484"(dendrite extension)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901610"(positive regulation of vesicle transport along microtubule)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039154|rcsb pdb:2WTK|rcsb pdb:4ZDR|rcsb pdb:5WXN|reactome:R-HSA-163680|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-380972|reactome:R-HSA-6804756|reactome:R-HSA-9614657|refseq:NP_000446.1|refseq:XP_005259675.1|dip:DIP-31317N|mint:MINT-8329733(identity) ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N|mint:MINT-8329739(identity) - - - figure legend:f2e|comment:homomint|comment:domino|comment:mint taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2012/03/09 2014/10/16 rogid:zBd9tuO3eqwjdeyPXdKKe6sHPHY9606 rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606 intact-crc:BD2C9D3EEA2CA3A7|rigid:VzWWh4pZDLitf2mnHf6eRZ65R2g false glutathione s tranferase tag:?-?(MINT-8329734) his tag:?-?(MINT-8329740)|mutation disrupting interaction:49-49(MINT-8329746) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q15831 uniprotkb:P63104 intact:EBI-306838|ensembl:ENSP00000324856|uniprotkb:E7EW76|uniprotkb:B2RBX7 intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465 psi-mi:stk11_human(display_long)|uniprotkb:STK11(gene name)|psi-mi:STK11(display_short)|uniprotkb:LKB1(gene name synonym)|uniprotkb:PJS(gene name synonym)|uniprotkb:Liver kinase B1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-19(gene name synonym) psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Bai et al. (2012) pubmed:22575644|mint:MINT-8329523 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7852554|mint:MINT-8329750 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000118046(gene)|ensembl:ENST00000326873(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001944"(vasculature development)|go:"GO:0002039"(p53 binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030275"(LRR domain binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043276"(anoikis)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0051645"(Golgi localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097484"(dendrite extension)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901610"(positive regulation of vesicle transport along microtubule)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039154|rcsb pdb:2WTK|rcsb pdb:4ZDR|rcsb pdb:5WXN|reactome:R-HSA-163680|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-380972|reactome:R-HSA-6804756|reactome:R-HSA-9614657|refseq:NP_000446.1|refseq:XP_005259675.1|dip:DIP-31317N|mint:MINT-8329752(identity) ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N|mint:MINT-8329758(identity) - - - figure legend:f3d|comment:homomint|comment:domino|comment:mint taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2012/03/09 2014/10/16 rogid:zBd9tuO3eqwjdeyPXdKKe6sHPHY9606 rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606 intact-crc:0C17989A057A2D93|rigid:NpZG0KXgHXSj1xlHebYFKrPCZMU false mutation disrupting interaction:336-336(MINT-8329755)|glutathione s tranferase tag:?-?(MINT-8329753) his tag:?-?(MINT-8329759) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q15831 uniprotkb:Q13131 intact:EBI-306838|ensembl:ENSP00000324856|uniprotkb:E7EW76|uniprotkb:B2RBX7 intact:EBI-1181405|uniprotkb:O00286|uniprotkb:Q5D0E1|uniprotkb:Q9UNQ4|uniprotkb:Q86VS1|intact:EBI-1383523|uniprotkb:A8MTQ6|uniprotkb:B2R7E1|ensembl:ENSP00000380317 psi-mi:stk11_human(display_long)|uniprotkb:STK11(gene name)|psi-mi:STK11(display_short)|uniprotkb:LKB1(gene name synonym)|uniprotkb:PJS(gene name synonym)|uniprotkb:Liver kinase B1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-19(gene name synonym) psi-mi:aapk1_human(display_long)|uniprotkb:PRKAA1(gene name)|psi-mi:PRKAA1(display_short)|uniprotkb:AMPK1(gene name synonym)|uniprotkb:Tau-protein kinase PRKAA1(gene name synonym)|uniprotkb:Acetyl-CoA carboxylase kinase(gene name synonym)|uniprotkb:Hydroxymethylglutaryl-CoA reductase kinase(gene name synonym) psi-mi:"MI:0096"(pull down) Bai et al. (2012) pubmed:22575644|mint:MINT-8329523 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7852554|mint:MINT-8329750 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000118046(gene)|ensembl:ENST00000326873(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001944"(vasculature development)|go:"GO:0002039"(p53 binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030275"(LRR domain binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043276"(anoikis)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0051645"(Golgi localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097484"(dendrite extension)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901610"(positive regulation of vesicle transport along microtubule)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039154|rcsb pdb:2WTK|rcsb pdb:4ZDR|rcsb pdb:5WXN|reactome:R-HSA-163680|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-380972|reactome:R-HSA-6804756|reactome:R-HSA-9614657|refseq:NP_000446.1|refseq:XP_005259675.1|dip:DIP-31317N|mint:MINT-8329752(identity) refseq:NP_006242.5|refseq:NP_996790.3|ensembl:ENSG00000132356(gene)|ensembl:ENST00000397128(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003682"(chromatin binding)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0009411"(response to UV)|go:"GO:0009631"(cold acclimation)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014823"(response to activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031000"(response to caffeine)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033135"(regulation of peptidyl-serine phosphorylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045542"(positive regulation of cholesterol biosynthetic process)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0046318"(negative regulation of glucosylceramide biosynthetic process)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0047322"("[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity")|go:"GO:0048156"(tau protein binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050405"([acetyl-CoA carboxylase] kinase activity)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0004672"(protein kinase activity)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0061744"(motor behavior)|go:"GO:0061762"(CAMKK-AMPK signaling cascade)|go:"GO:0062028"(regulation of stress granule assembly)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120188"(regulation of bile acid secretion)|go:"GO:1901563"(response to camptothecin)|go:"GO:1903109"(positive regulation of mitochondrial transcription)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1904428"(negative regulation of tubulin deacetylation)|go:"GO:1904486"(response to 17alpha-ethynylestradiol)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR028797|interpro:IPR032270|interpro:IPR039137|mint:Q13131|rcsb pdb:4RED|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:5EZV|rcsb pdb:6C9F|rcsb pdb:6C9G|rcsb pdb:6C9H|rcsb pdb:6C9J|reactome:R-HSA-1632852|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9619483|dip:DIP-39973N|mint:MINT-8329763(identity) - - - figure legend:f3d|comment:homomint|comment:domino|comment:mint taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2012/03/09 2014/10/16 rogid:zBd9tuO3eqwjdeyPXdKKe6sHPHY9606 rogid:isWWA5k0AqbXwXq5Bj+pk0joegU9606 intact-crc:0C17989A057A2D93|rigid:NpZG0KXgHXSj1xlHebYFKrPCZMU false mutation disrupting interaction:336-336(MINT-8329755)|glutathione s tranferase tag:?-?(MINT-8329753) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P63104 uniprotkb:Q15831 intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465 intact:EBI-306838|ensembl:ENSP00000324856|uniprotkb:E7EW76|uniprotkb:B2RBX7 psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:stk11_human(display_long)|uniprotkb:STK11(gene name)|psi-mi:STK11(display_short)|uniprotkb:LKB1(gene name synonym)|uniprotkb:PJS(gene name synonym)|uniprotkb:Liver kinase B1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-19(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Bai et al. (2012) pubmed:22575644|mint:MINT-8329523 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7852587|mint:MINT-8329787 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N|mint:MINT-8329795(identity) ensembl:ENSG00000118046(gene)|ensembl:ENST00000326873(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001944"(vasculature development)|go:"GO:0002039"(p53 binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030275"(LRR domain binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043276"(anoikis)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0051645"(Golgi localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097484"(dendrite extension)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901610"(positive regulation of vesicle transport along microtubule)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:0050852"(T cell receptor signaling pathway)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039154|rcsb pdb:2WTK|rcsb pdb:4ZDR|rcsb pdb:5WXN|reactome:R-HSA-163680|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-380972|reactome:R-HSA-6804756|reactome:R-HSA-9614657|refseq:NP_000446.1|refseq:XP_005259675.1|dip:DIP-31317N|mint:MINT-8329789(identity) go:"GO:0005737"(cytoplasm) - - figure legend:f5b|comment:homomint|comment:domino|comment:mint taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2012/03/09 2014/10/16 rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606 rogid:zBd9tuO3eqwjdeyPXdKKe6sHPHY9606 intact-crc:9AE6C14D0B77FB5D|rigid:VzWWh4pZDLitf2mnHf6eRZ65R2g false fusion protein:?-?(MINT-8329796) green fluorescent protein tag:?-?(MINT-8329792) - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)