#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9EPK5 uniprotkb:Q08775 intact:EBI-1211920|uniprotkb:Q3UQ69|uniprotkb:Q3UQM0|uniprotkb:Q99KI4|ensembl:ENSMUSP00000029380 intact:EBI-903354|uniprotkb:O35183|uniprotkb:Q08776|uniprotkb:Q9JLN0|uniprotkb:Q9QUQ6|uniprotkb:Q9QY29|uniprotkb:Q9R0U4|uniprotkb:Q9Z2J7 psi-mi:wwtr1_mouse(display_long)|uniprotkb:Wwtr1(gene name)|psi-mi:Wwtr1(display_short)|uniprotkb:Taz(gene name synonym)|uniprotkb:Transcriptional coactivator with PDZ-binding motif(gene name synonym) psi-mi:runx2_mouse(display_long)|uniprotkb:Runx2(gene name)|psi-mi:Runx2(display_short)|uniprotkb:Aml3(gene name synonym)|uniprotkb:Cbfa1(gene name synonym)|uniprotkb:Osf2(gene name synonym)|uniprotkb:Pebp2a(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-1(gene name synonym)|uniprotkb:Acute myeloid leukemia 3 protein(gene name synonym)|uniprotkb:Oncogene AML-3(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha A subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha A subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha A subunit(gene name synonym)|uniprotkb:Osteoblast-specific transcription factor 2(gene name synonym) psi-mi:"MI:0096"(pull down) Byun et al. (2012) pubmed:22575641|mint:MINT-8329074 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7847673|mint:MINT-8329079 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001161753.1|refseq:NP_598545.2|dip:DIP-39476N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032835"(glomerulus development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:Q9EPK5|rcsb pdb:5GN0|reactome:R-MMU-2028269|reactome:R-MMU-2032785|reactome:R-MMU-2173796|ensembl:ENSMUSG00000027803(gene)|ensembl:ENSMUST00000029380(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003015"(heart process)|go:"GO:0003713"(transcription coactivator activity)|mint:MINT-8329081(identity) refseq:NP_001139510.1|refseq:NP_033950.2|refseq:NP_001258556.1|refseq:XP_006523607.1|refseq:XP_006523608.1|mint:Q08775|dip:DIP-36316N|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0040036"(regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042487"(regulation of odontogenesis of dentin-containing tooth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|interpro:IPR013711(Runx inhibition)|interpro:IPR027384|reactome:R-MMU-8878166|reactome:R-MMU-8939902|reactome:R-MMU-8940973|reactome:R-MMU-8941326|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002051"(osteoblast fate commitment)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002063"(chondrocyte development)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)|mint:MINT-8329082(identity) - - - figure legend:f3a|comment:mint taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/03/06 2014/10/16 rogid:K3vBlwaBtOtY1ERZlFti83hwZdc10090 rogid:WYs7JxHzJasUS7fx5/LzgKJEjEY10090 intact-crc:53F093EEF27D6C7F|rigid:WxrNVk6tmSP4Al9jzhOLdWYgGwc false flag tag:?-?(MINT-8329084) ha tag:?-?(MINT-8329088) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot)