#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0DJJ0 uniprotkb:O75044 intact:EBI-6137765|ensembl:ENSP00000478290 intact:EBI-1051034|ensembl:ENSP00000459615|uniprotkb:A2RUF3 psi-mi:srg2c_human(display_long)|uniprotkb:SLIT-ROBO Rho GTPase activating protein 2 pseudogene 1(gene name synonym)|uniprotkb:SRGAP2P1(gene name synonym)|uniprotkb:SRGAP2C(gene name)|psi-mi:SRGAP2C(display_short) psi-mi:srgp2_human(display_long)|uniprotkb:Formin-binding protein 2(gene name synonym)|uniprotkb:SRGAP2(gene name)|psi-mi:SRGAP2(display_short)|uniprotkb:FNBP2(gene name synonym)|uniprotkb:KIAA0456(gene name synonym)|uniprotkb:ARHGAP34(gene name synonym)|uniprotkb:Rho GTPase-activating protein 34(gene name synonym)|uniprotkb:SRGAP2A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Charrier et al. (2012) pubmed:22559944|imex:IM-17345 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6137403|imex:IM-17345-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001316913.1|ensembl:ENSG00000171943(gene)|ensembl:ENST00000367123(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR027267|interpro:IPR030252|interpro:IPR031160|go:"GO:0021816"(extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration) refseq:NP_001164108.1|refseq:NP_056141.2|ensembl:ENSG00000266028(gene)|ensembl:ENST00000573034(transcript)|go:"GO:0003363"(lamellipodium assembly involved in ameboidal cell migration)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021816"(extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051014"(actin filament severing)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060996"(dendritic spine development)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR030252|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|mint:O75044|rcsb pdb:2DL8|rcsb pdb:4RTT|rcsb pdb:4RUG|rcsb pdb:5I6J|rcsb pdb:5I6R|rcsb pdb:5I7D|reactome:R-HSA-428543|reactome:R-HSA-5663220|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|dip:DIP-37618N|refseq:XP_005277567.1 - comment:"no amino acid sequence quoted 25/5/2012, only mRNA. PRedicted 459 aas, human (brain) specific paralog of SRGAP2A." - figure legend:fig 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/05/23 2018/01/16 rogid:RrpMahYio4Jsn/2xK1UJRgQ0+Fo9606 rogid:/0NBTrPy/51L4LGytNP/80OifEE9606 intact-crc:A58E70D11BF2AAA4|rigid:EQGlZ0I5XvjxzOpAtZB6oU9dTCk false ha tag:?-? enhanced green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P0DJJ0 uniprotkb:P0DJJ0 intact:EBI-6137765|ensembl:ENSP00000478290 intact:EBI-6137765|ensembl:ENSP00000478290 psi-mi:srg2c_human(display_long)|uniprotkb:SLIT-ROBO Rho GTPase activating protein 2 pseudogene 1(gene name synonym)|uniprotkb:SRGAP2P1(gene name synonym)|uniprotkb:SRGAP2C(gene name)|psi-mi:SRGAP2C(display_short) psi-mi:srg2c_human(display_long)|uniprotkb:SLIT-ROBO Rho GTPase activating protein 2 pseudogene 1(gene name synonym)|uniprotkb:SRGAP2P1(gene name synonym)|uniprotkb:SRGAP2C(gene name)|psi-mi:SRGAP2C(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Charrier et al. (2012) pubmed:22559944|imex:IM-17345 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-6137769|imex:IM-17345-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001316913.1|ensembl:ENSG00000171943(gene)|ensembl:ENST00000367123(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR027267|interpro:IPR030252|interpro:IPR031160|go:"GO:0021816"(extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration) refseq:NP_001316913.1|ensembl:ENSG00000171943(gene)|ensembl:ENST00000367123(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR027267|interpro:IPR030252|interpro:IPR031160|go:"GO:0021816"(extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration) - comment:"no amino acid sequence quoted 25/5/2012, only mRNA. PRedicted 459 aas, human (brain) specific paralog of SRGAP2A." comment:"no amino acid sequence quoted 25/5/2012, only mRNA. PRedicted 459 aas, human (brain) specific paralog of SRGAP2A." figure legend:fig 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2012/05/23 2014/10/16 rogid:RrpMahYio4Jsn/2xK1UJRgQ0+Fo9606 rogid:RrpMahYio4Jsn/2xK1UJRgQ0+Fo9606 intact-crc:0A9F49D767C8FF1F|rigid:8tG+KM9GTwuy6tk64ClBY7IIOSc false enhanced green fluorescent protein tag:?-? ha tag:?-? 2 - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)