#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q02241 uniprotkb:P62331 intact:EBI-306852|uniprotkb:Q8WVP0|ensembl:ENSP00000260363|ensembl:ENSP00000497065|intact:EBI-2558308|uniprotkb:B4E1K0 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 psi-mi:kif23_human(display_long)|uniprotkb:KIF23(gene name)|psi-mi:KIF23(display_short)|uniprotkb:KNSL5(gene name synonym)|uniprotkb:MKLP1(gene name synonym)|uniprotkb:Mitotic kinesin-like protein 1(gene name synonym)|uniprotkb:Kinesin-like protein 5(gene name synonym) psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:"MI:0114"(x-ray crystallography) Makyio et al. (2012) doi:10.1038/emboj.2012.89|pubmed:22522702|imex:IM-18769|mint:MINT-8395701 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7832065|mint:MINT-8395709|imex:IM-18769-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004847.2|refseq:NP_612565.1|ensembl:ENSG00000137807(gene)|ensembl:ENST00000260363(transcript)|ensembl:ENST00000647715(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030496"(midbody)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|go:"GO:0000281"(mitotic cytokinesis)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR038105|mint:Q02241|rcsb pdb:3VHX|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-68884|interpro:IPR032384|reactome:R-HSA-983189|ensembl:ENSP00000260363|ensembl:ENST00000352331|ensembl:ENSP00000304978|ensembl:ENSP00000497065|dip:DIP-40359N|mint:MINT-8395712(identity) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-8395711(identity) - comment:"Stoichiometry: 2.2" comment:"Stoichiometry: 2.2" comment:homomint|comment:mint|figure legend:ST1 f4 f5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/10/01 2022/01/20 rogid:akVjKfOv4g4nEsGN8E3lQ2vCseQ9606 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 intact-crc:074B13408625D7F1|rigid:wfAV7ObdkJfWpTEYXcKFgfu0He0 false binding-associated region:690-807(MINT-8395717) binding-associated region:13-175(MINT-8395721) 2 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62331 uniprotkb:Q02241 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 intact:EBI-306852|uniprotkb:Q8WVP0|ensembl:ENSP00000260363|ensembl:ENSP00000497065|intact:EBI-2558308|uniprotkb:B4E1K0 psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:kif23_human(display_long)|uniprotkb:KIF23(gene name)|psi-mi:KIF23(display_short)|uniprotkb:KNSL5(gene name synonym)|uniprotkb:MKLP1(gene name synonym)|uniprotkb:Mitotic kinesin-like protein 1(gene name synonym)|uniprotkb:Kinesin-like protein 5(gene name synonym) psi-mi:"MI:0826"(x ray scattering) Makyio et al. (2012) doi:10.1038/emboj.2012.89|pubmed:22522702|imex:IM-18769|mint:MINT-8395701 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7832095|mint:MINT-8395740|imex:IM-18769-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-8395742(identity) refseq:NP_004847.2|refseq:NP_612565.1|ensembl:ENSG00000137807(gene)|ensembl:ENST00000260363(transcript)|ensembl:ENST00000647715(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030496"(midbody)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|go:"GO:0000281"(mitotic cytokinesis)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR038105|mint:Q02241|rcsb pdb:3VHX|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-68884|interpro:IPR032384|reactome:R-HSA-983189|ensembl:ENSP00000260363|ensembl:ENST00000352331|ensembl:ENSP00000304978|ensembl:ENSP00000497065|dip:DIP-40359N|mint:MINT-8395746(identity) - comment:"Stoichiometry: 2.2" comment:"Stoichiometry: 2.2" figure legend:f4c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/10/01 2022/01/20 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 rogid:akVjKfOv4g4nEsGN8E3lQ2vCseQ9606 intact-crc:99AB67B3469D7E1A|rigid:wfAV7ObdkJfWpTEYXcKFgfu0He0 false binding-associated region:13-175(MINT-8395743) binding-associated region:690-807(MINT-8395747) 2 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02241 uniprotkb:P62331 intact:EBI-306852|uniprotkb:Q8WVP0|ensembl:ENSP00000260363|ensembl:ENSP00000497065|intact:EBI-2558308|uniprotkb:B4E1K0 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 psi-mi:kif23_human(display_long)|uniprotkb:KIF23(gene name)|psi-mi:KIF23(display_short)|uniprotkb:KNSL5(gene name synonym)|uniprotkb:MKLP1(gene name synonym)|uniprotkb:Mitotic kinesin-like protein 1(gene name synonym)|uniprotkb:Kinesin-like protein 5(gene name synonym) psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Makyio et al. (2012) doi:10.1038/emboj.2012.89|pubmed:22522702|imex:IM-18769|mint:MINT-8395701 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7832124|mint:MINT-8395795|imex:IM-18769-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004847.2|refseq:NP_612565.1|ensembl:ENSG00000137807(gene)|ensembl:ENST00000260363(transcript)|ensembl:ENST00000647715(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030496"(midbody)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|go:"GO:0000281"(mitotic cytokinesis)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR038105|mint:Q02241|rcsb pdb:3VHX|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-68884|interpro:IPR032384|reactome:R-HSA-983189|ensembl:ENSP00000260363|ensembl:ENST00000352331|ensembl:ENSP00000304978|ensembl:ENSP00000497065|dip:DIP-40359N|mint:MINT-8395803(identity) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-8395797(identity) - - - figure legend:f2e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) temp interaction:15.0x10^6(molar) 2012/10/01 2014/10/16 rogid:akVjKfOv4g4nEsGN8E3lQ2vCseQ9606 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 intact-crc:56A2BC5DE8D70BC3|rigid:wfAV7ObdkJfWpTEYXcKFgfu0He0 false binding-associated region:690-807(MINT-8395804)|glutathione s tranferase tag:?-?(MINT-8395806) his tag:?-?(MINT-8395814)|binding-associated region:13-175(MINT-8395816) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62331 uniprotkb:Q02241 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 intact:EBI-306852|uniprotkb:Q8WVP0|ensembl:ENSP00000260363|ensembl:ENSP00000497065|intact:EBI-2558308|uniprotkb:B4E1K0 psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:kif23_human(display_long)|uniprotkb:KIF23(gene name)|psi-mi:KIF23(display_short)|uniprotkb:KNSL5(gene name synonym)|uniprotkb:MKLP1(gene name synonym)|uniprotkb:Mitotic kinesin-like protein 1(gene name synonym)|uniprotkb:Kinesin-like protein 5(gene name synonym) psi-mi:"MI:0096"(pull down) Makyio et al. (2012) doi:10.1038/emboj.2012.89|pubmed:22522702|imex:IM-18769|mint:MINT-8395701 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7832201|mint:MINT-8395756|imex:IM-18769-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-8395758(identity) refseq:NP_004847.2|refseq:NP_612565.1|ensembl:ENSG00000137807(gene)|ensembl:ENST00000260363(transcript)|ensembl:ENST00000647715(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030496"(midbody)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|go:"GO:0000281"(mitotic cytokinesis)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR038105|mint:Q02241|rcsb pdb:3VHX|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-68884|interpro:IPR032384|reactome:R-HSA-983189|ensembl:ENSP00000260363|ensembl:ENST00000352331|ensembl:ENSP00000304978|ensembl:ENSP00000497065|dip:DIP-40359N|mint:MINT-8395762(identity) - - - comment:homomint|comment:mint|figure legend:f2b f2c f2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/10/01 2014/10/16 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 rogid:akVjKfOv4g4nEsGN8E3lQ2vCseQ9606 intact-crc:59F907FB659D8F40|rigid:wfAV7ObdkJfWpTEYXcKFgfu0He0 false mutation increasing interaction:67-67(MINT-8395776)|ha tag:?-?(MINT-8395770) glutathione s tranferase tag:?-?(MINT-8395773)|binding-associated region:690-807(MINT-8395763) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02241 uniprotkb:P62331 intact:EBI-306852|uniprotkb:Q8WVP0|ensembl:ENSP00000260363|ensembl:ENSP00000497065|intact:EBI-2558308|uniprotkb:B4E1K0 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 psi-mi:kif23_human(display_long)|uniprotkb:KIF23(gene name)|psi-mi:KIF23(display_short)|uniprotkb:KNSL5(gene name synonym)|uniprotkb:MKLP1(gene name synonym)|uniprotkb:Mitotic kinesin-like protein 1(gene name synonym)|uniprotkb:Kinesin-like protein 5(gene name synonym) psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:"MI:0096"(pull down) Makyio et al. (2012) doi:10.1038/emboj.2012.89|pubmed:22522702|imex:IM-18769|mint:MINT-8395701 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7832296|mint:MINT-8395860|imex:IM-18769-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004847.2|refseq:NP_612565.1|ensembl:ENSG00000137807(gene)|ensembl:ENST00000260363(transcript)|ensembl:ENST00000647715(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030496"(midbody)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|go:"GO:0000281"(mitotic cytokinesis)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR038105|mint:Q02241|rcsb pdb:3VHX|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-68884|interpro:IPR032384|reactome:R-HSA-983189|ensembl:ENSP00000260363|ensembl:ENST00000352331|ensembl:ENSP00000304978|ensembl:ENSP00000497065|dip:DIP-40359N|mint:MINT-8395868(identity) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-8395862(identity) - - - figure legend:f6a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/10/01 2014/10/16 rogid:akVjKfOv4g4nEsGN8E3lQ2vCseQ9606 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 intact-crc:6306EAD5897CB26D|rigid:wfAV7ObdkJfWpTEYXcKFgfu0He0 false binding-associated region:690-807(MINT-8395871)|glutathione s tranferase tag:?-?(MINT-8395869) mutation disrupting interaction:77-77(MINT-8395876)|ha tag:?-?(MINT-8395865)|mutation disrupting interaction:67-67(MINT-8395863) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q02241 uniprotkb:P62331 intact:EBI-306852|uniprotkb:Q8WVP0|ensembl:ENSP00000260363|ensembl:ENSP00000497065|intact:EBI-2558308|uniprotkb:B4E1K0 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 psi-mi:kif23_human(display_long)|uniprotkb:KIF23(gene name)|psi-mi:KIF23(display_short)|uniprotkb:KNSL5(gene name synonym)|uniprotkb:MKLP1(gene name synonym)|uniprotkb:Mitotic kinesin-like protein 1(gene name synonym)|uniprotkb:Kinesin-like protein 5(gene name synonym) psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:"MI:0096"(pull down) Makyio et al. (2012) doi:10.1038/emboj.2012.89|pubmed:22522702|imex:IM-18769|mint:MINT-8395701 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7832252|mint:MINT-8395779|imex:IM-18769-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004847.2|refseq:NP_612565.1|ensembl:ENSG00000137807(gene)|ensembl:ENST00000260363(transcript)|ensembl:ENST00000647715(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030496"(midbody)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|go:"GO:0000281"(mitotic cytokinesis)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR038105|mint:Q02241|rcsb pdb:3VHX|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-68884|interpro:IPR032384|reactome:R-HSA-983189|ensembl:ENSP00000260363|ensembl:ENST00000352331|ensembl:ENSP00000304978|ensembl:ENSP00000497065|dip:DIP-40359N|mint:MINT-8395787(identity) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-8395781(identity) - - - comment:homomint|comment:mint|figure legend:f2b f2c f2d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/10/01 2014/10/16 rogid:akVjKfOv4g4nEsGN8E3lQ2vCseQ9606 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 intact-crc:1F418E3D72C9B4C6|rigid:wfAV7ObdkJfWpTEYXcKFgfu0He0 false glutathione s tranferase tag:?-?(MINT-8395788)|binding-associated region:690-807(MINT-8395790) ha tag:?-?(MINT-8395784)|mutation decreasing interaction:27-27(MINT-8395782) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UJY5 uniprotkb:P62331 intact:EBI-447141|uniprotkb:Q5TG07|uniprotkb:Q9BW94|uniprotkb:Q9UG00|uniprotkb:Q9UGW0|uniprotkb:Q9UGW1|uniprotkb:A8K3D3|uniprotkb:Q5R3N1|uniprotkb:Q6IC75|uniprotkb:B0QYR7|uniprotkb:Q86YA9|uniprotkb:Q8NCS6|ensembl:ENSP00000341344 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 psi-mi:gga1_human(display_long)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 1(gene name synonym)|uniprotkb:Gamma-adaptin-related protein 1(gene name synonym)|uniprotkb:GGA1(gene name)|psi-mi:GGA1(display_short) psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:"MI:0096"(pull down) Makyio et al. (2012) doi:10.1038/emboj.2012.89|pubmed:22522702|imex:IM-18769|mint:MINT-8395701 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7832340|mint:MINT-8395879|imex:IM-18769-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001560.1|refseq:NP_001166158.1|refseq:NP_001166159.1|refseq:NP_037497.1|refseq:XP_005261574.1|refseq:XP_011528424.1|refseq:XP_005261577.1|refseq:XP_006724292.1|refseq:XP_016884249.1|refseq:XP_016884250.1|refseq:XP_016884251.1|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:1901998"(toxin transport)|go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR038425|interpro:IPR041198|mint:Q9UJY5|rcsb pdb:1J2J|rcsb pdb:1JWF|rcsb pdb:1JWG|rcsb pdb:1NA8|rcsb pdb:1NAF|rcsb pdb:1NWM|rcsb pdb:1O3X|rcsb pdb:1OM9|rcsb pdb:1OXZ|rcsb pdb:1PY1|rcsb pdb:1UJJ|rcsb pdb:1UJK|rcsb pdb:1X79|rcsb pdb:2DWX|rcsb pdb:2DWY|rcsb pdb:3G2S|rcsb pdb:3G2T|rcsb pdb:3G2U|rcsb pdb:3G2V|rcsb pdb:3G2W|reactome:R-HSA-8854214|reactome:R-HSA-977225|ensembl:ENSG00000100083(gene)|ensembl:ENST00000343632(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008104"(protein localization)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|mint:MINT-8395889(identity) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-8395881(identity) - - - figure legend:f6a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/10/01 2014/10/16 rogid:3n7Nia4JzMiDja0I7mUcyihFFBc9606 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 intact-crc:8315CF4E4C1DC4A3|rigid:axb/zhs4gqyXCucfg3HW/ESP6ZQ false glutathione s tranferase tag:?-?(MINT-8395892) ha tag:?-?(MINT-8395886)|mutation disrupting interaction:77-77(MINT-8395882)|mutation disrupting interaction:67-67(MINT-8395884) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UJY5 uniprotkb:P62331 intact:EBI-447141|uniprotkb:Q5TG07|uniprotkb:Q9BW94|uniprotkb:Q9UG00|uniprotkb:Q9UGW0|uniprotkb:Q9UGW1|uniprotkb:A8K3D3|uniprotkb:Q5R3N1|uniprotkb:Q6IC75|uniprotkb:B0QYR7|uniprotkb:Q86YA9|uniprotkb:Q8NCS6|ensembl:ENSP00000341344 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 psi-mi:gga1_human(display_long)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 1(gene name synonym)|uniprotkb:Gamma-adaptin-related protein 1(gene name synonym)|uniprotkb:GGA1(gene name)|psi-mi:GGA1(display_short) psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:"MI:0096"(pull down) Makyio et al. (2012) doi:10.1038/emboj.2012.89|pubmed:22522702|imex:IM-18769|mint:MINT-8395701 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7832400|mint:MINT-8395897|imex:IM-18769-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001001560.1|refseq:NP_001166158.1|refseq:NP_001166159.1|refseq:NP_037497.1|refseq:XP_005261574.1|refseq:XP_011528424.1|refseq:XP_005261577.1|refseq:XP_006724292.1|refseq:XP_016884249.1|refseq:XP_016884250.1|refseq:XP_016884251.1|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:1901998"(toxin transport)|go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR038425|interpro:IPR041198|mint:Q9UJY5|rcsb pdb:1J2J|rcsb pdb:1JWF|rcsb pdb:1JWG|rcsb pdb:1NA8|rcsb pdb:1NAF|rcsb pdb:1NWM|rcsb pdb:1O3X|rcsb pdb:1OM9|rcsb pdb:1OXZ|rcsb pdb:1PY1|rcsb pdb:1UJJ|rcsb pdb:1UJK|rcsb pdb:1X79|rcsb pdb:2DWX|rcsb pdb:2DWY|rcsb pdb:3G2S|rcsb pdb:3G2T|rcsb pdb:3G2U|rcsb pdb:3G2V|rcsb pdb:3G2W|reactome:R-HSA-8854214|reactome:R-HSA-977225|ensembl:ENSG00000100083(gene)|ensembl:ENST00000343632(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008104"(protein localization)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|mint:MINT-8395907(identity) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-8395899(identity) - - - figure legend:f6a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/10/01 2014/10/16 rogid:3n7Nia4JzMiDja0I7mUcyihFFBc9606 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 intact-crc:2777638E33C04EAD|rigid:axb/zhs4gqyXCucfg3HW/ESP6ZQ false glutathione s tranferase tag:?-?(MINT-8395908) mutation disrupting interaction:76-76(MINT-8395904)|mutation disrupting interaction:67-67(MINT-8395902)|ha tag:?-?(MINT-8395900) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P62331 uniprotkb:Q86YS3 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 intact:EBI-949727|uniprotkb:Q969D8|ensembl:ENSP00000482620|uniprotkb:Q52LI1|uniprotkb:Q8N829|uniprotkb:Q8NDT7 psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:rfip4_human(display_long)|uniprotkb:RAB11FIP4(gene name)|psi-mi:RAB11FIP4(display_short)|uniprotkb:KIAA1821(gene name synonym)|uniprotkb:ARFO2(gene name synonym)|uniprotkb:Arfophilin-2(gene name synonym) psi-mi:"MI:0096"(pull down) Makyio et al. (2012) doi:10.1038/emboj.2012.89|pubmed:22522702|imex:IM-18769|mint:MINT-8395701 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7832452|mint:MINT-8395913|imex:IM-18769-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-8395915(identity) ensembl:ENSG00000131242(gene)|ensembl:ENST00000621161(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR019018|interpro:IPR037245|mint:Q86YS3|refseq:NP_116321.2|dip:DIP-47495N|refseq:NP_001333677.1|refseq:NP_001333678.1|refseq:NP_001290471.2|mint:MINT-8395923(identity) - - - comment:homomint|comment:mint|figure legend:f6a F6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/10/01 2014/10/16 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 rogid:282TFWeYgK3VUODOQwEUM58cfsI9606 intact-crc:408C18C7479E9421|rigid:ve0IVy8be4klwFlFwQD2TMQn95k false mutation disrupting interaction:67-67(MINT-8395918)|ha tag:?-?(MINT-8395920)|mutation disrupting interaction:76-76(MINT-8395916) glutathione s tranferase tag:?-?(MINT-8395924)|binding-associated region:484-613(MINT-8395928) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O60271 uniprotkb:P62331 intact:EBI-1023301|uniprotkb:O60905|uniprotkb:Q3KQU8|uniprotkb:Q3MKM7|uniprotkb:Q86WC7|uniprotkb:Q86WC8|uniprotkb:Q8IZX7|uniprotkb:Q96II0|uniprotkb:Q9H811|uniprotkb:A8MSX0|uniprotkb:B4DHH2|uniprotkb:A6H8U5|intact:EBI-2560890|ensembl:ENSP00000262013 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 psi-mi:jip4_human(display_long)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Human lung cancer oncogene 6 protein(gene name synonym)|uniprotkb:Proliferation-inducing protein 6(gene name synonym)|uniprotkb:Sperm-specific protein(gene name synonym)|uniprotkb:Sperm surface protein(gene name synonym)|uniprotkb:Protein highly expressed in testis(gene name synonym)|uniprotkb:Sunday driver 1(gene name synonym)|uniprotkb:Cancer/testis antigen 89(gene name synonym)|uniprotkb:HLC6(orf name)|uniprotkb:SPAG9(gene name)|psi-mi:SPAG9(display_short)|uniprotkb:HSS(gene name synonym)|uniprotkb:KIAA0516(gene name synonym)|uniprotkb:MAPK8IP4(gene name synonym)|uniprotkb:SYD1(gene name synonym) psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:"MI:0096"(pull down) Makyio et al. (2012) doi:10.1038/emboj.2012.89|pubmed:22522702|imex:IM-18769|mint:MINT-8395701 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7832567|mint:MINT-8395949|imex:IM-18769-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001123999.1|refseq:NP_001238900.1|refseq:NP_001124000.1|refseq:NP_003962.3|ensembl:ENSG00000008294(gene)|ensembl:ENST00000262013(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903860"(negative regulation of dendrite extension)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:O60271|rcsb pdb:2W83|reactome:R-HSA-525793|mint:MINT-8395959(identity) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-8395951(identity) - - - figure legend:f6a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/10/01 2014/10/16 rogid:UsItS/q6arsUKVnp+hGuBZE3P809606 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 intact-crc:CC10C68CF90A5CC3|rigid:e7Dmseef1uEk36T8KBF+Z79vWgQ false glutathione s tranferase tag:?-?(MINT-8395960) mutation disrupting interaction:67-67(MINT-8395954)|mutation disrupting interaction:77-77(MINT-8395952)|ha tag:?-?(MINT-8395956) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P62331 uniprotkb:Q86YS3 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 intact:EBI-949727|uniprotkb:Q969D8|ensembl:ENSP00000482620|uniprotkb:Q52LI1|uniprotkb:Q8N829|uniprotkb:Q8NDT7 psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:rfip4_human(display_long)|uniprotkb:RAB11FIP4(gene name)|psi-mi:RAB11FIP4(display_short)|uniprotkb:KIAA1821(gene name synonym)|uniprotkb:ARFO2(gene name synonym)|uniprotkb:Arfophilin-2(gene name synonym) psi-mi:"MI:0096"(pull down) Makyio et al. (2012) doi:10.1038/emboj.2012.89|pubmed:22522702|imex:IM-18769|mint:MINT-8395701 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7832512|mint:MINT-8395931|imex:IM-18769-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-8395933(identity) ensembl:ENSG00000131242(gene)|ensembl:ENST00000621161(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR019018|interpro:IPR037245|mint:Q86YS3|refseq:NP_116321.2|dip:DIP-47495N|refseq:NP_001333677.1|refseq:NP_001333678.1|refseq:NP_001290471.2|mint:MINT-8395941(identity) - - - comment:homomint|comment:mint|figure legend:f6a F6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/10/01 2014/10/16 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 rogid:282TFWeYgK3VUODOQwEUM58cfsI9606 intact-crc:1B3C4464EB99AE2E|rigid:ve0IVy8be4klwFlFwQD2TMQn95k false mutation disrupting interaction:67-67(MINT-8395936)|mutation disrupting interaction:77-77(MINT-8395938)|ha tag:?-?(MINT-8395934) glutathione s tranferase tag:?-?(MINT-8395944)|binding-associated region:484-613(MINT-8395942) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UJY4 uniprotkb:P62331 intact:EBI-447646|uniprotkb:O14564|uniprotkb:Q9NYN2|uniprotkb:Q9UPS2|uniprotkb:D3DWF0|ensembl:ENSP00000311962 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 psi-mi:gga2_human(display_long)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 2(gene name synonym)|uniprotkb:Gamma-adaptin-related protein 2(gene name synonym)|uniprotkb:VHS domain and ear domain of gamma-adaptin(gene name synonym)|uniprotkb:GGA2(gene name)|psi-mi:GGA2(display_short)|uniprotkb:KIAA1080(gene name synonym) psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:"MI:0096"(pull down) Makyio et al. (2012) doi:10.1038/emboj.2012.89|pubmed:22522702|imex:IM-18769|mint:MINT-8395701 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7832689|mint:MINT-8395984|imex:IM-18769-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055859.1|dip:DIP-31601N|ensembl:ENSG00000103365(gene)|ensembl:ENST00000309859(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR038425|interpro:IPR041198|mint:Q9UJY4|rcsb pdb:1MHQ|reactome:R-HSA-8854214|reactome:R-HSA-977225|mint:MINT-8395994(identity) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-8395986(identity) - - - comment:homomint|comment:mint|figure legend:f6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/10/01 2014/10/16 rogid:VD3+z3TdZr7Ius0oloo8bnMhwjQ9606 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 intact-crc:79D519BD89DEC91C|rigid:98Z1GT5G38EUVmBn2I5MH8Qlo8k false glutathione s tranferase tag:?-?(MINT-8395995) ha tag:?-?(MINT-8395991) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P62331 uniprotkb:O60271 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 intact:EBI-1023301|uniprotkb:O60905|uniprotkb:Q3KQU8|uniprotkb:Q3MKM7|uniprotkb:Q86WC7|uniprotkb:Q86WC8|uniprotkb:Q8IZX7|uniprotkb:Q96II0|uniprotkb:Q9H811|uniprotkb:A8MSX0|uniprotkb:B4DHH2|uniprotkb:A6H8U5|intact:EBI-2560890|ensembl:ENSP00000262013 psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:jip4_human(display_long)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Human lung cancer oncogene 6 protein(gene name synonym)|uniprotkb:Proliferation-inducing protein 6(gene name synonym)|uniprotkb:Sperm-specific protein(gene name synonym)|uniprotkb:Sperm surface protein(gene name synonym)|uniprotkb:Protein highly expressed in testis(gene name synonym)|uniprotkb:Sunday driver 1(gene name synonym)|uniprotkb:Cancer/testis antigen 89(gene name synonym)|uniprotkb:HLC6(orf name)|uniprotkb:SPAG9(gene name)|psi-mi:SPAG9(display_short)|uniprotkb:HSS(gene name synonym)|uniprotkb:KIAA0516(gene name synonym)|uniprotkb:MAPK8IP4(gene name synonym)|uniprotkb:SYD1(gene name synonym) psi-mi:"MI:0096"(pull down) Makyio et al. (2012) doi:10.1038/emboj.2012.89|pubmed:22522702|imex:IM-18769|mint:MINT-8395701 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7832663|mint:MINT-8395968|imex:IM-18769-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-8395970(identity) refseq:NP_001123999.1|refseq:NP_001238900.1|refseq:NP_001124000.1|refseq:NP_003962.3|ensembl:ENSG00000008294(gene)|ensembl:ENST00000262013(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903860"(negative regulation of dendrite extension)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:O60271|rcsb pdb:2W83|reactome:R-HSA-525793|mint:MINT-8395978(identity) - - - figure legend:f6a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/10/01 2014/10/16 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 rogid:UsItS/q6arsUKVnp+hGuBZE3P809606 intact-crc:68726A4C86D7D6CD|rigid:e7Dmseef1uEk36T8KBF+Z79vWgQ false ha tag:?-?(MINT-8395971)|mutation disrupting interaction:76-76(MINT-8395975)|mutation disrupting interaction:67-67(MINT-8395973) glutathione s tranferase tag:?-?(MINT-8395979) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02241 uniprotkb:P62331 intact:EBI-306852|uniprotkb:Q8WVP0|ensembl:ENSP00000260363|ensembl:ENSP00000497065|intact:EBI-2558308|uniprotkb:B4E1K0 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 psi-mi:kif23_human(display_long)|uniprotkb:KIF23(gene name)|psi-mi:KIF23(display_short)|uniprotkb:KNSL5(gene name synonym)|uniprotkb:MKLP1(gene name synonym)|uniprotkb:Mitotic kinesin-like protein 1(gene name synonym)|uniprotkb:Kinesin-like protein 5(gene name synonym) psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:"MI:0096"(pull down) Makyio et al. (2012) doi:10.1038/emboj.2012.89|pubmed:22522702|imex:IM-18769|mint:MINT-8395701 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7832707|mint:MINT-8396005|imex:IM-18769-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004847.2|refseq:NP_612565.1|ensembl:ENSG00000137807(gene)|ensembl:ENST00000260363(transcript)|ensembl:ENST00000647715(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030496"(midbody)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|go:"GO:0000281"(mitotic cytokinesis)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR038105|mint:Q02241|rcsb pdb:3VHX|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-68884|interpro:IPR032384|reactome:R-HSA-983189|ensembl:ENSP00000260363|ensembl:ENST00000352331|ensembl:ENSP00000304978|ensembl:ENSP00000497065|dip:DIP-40359N|mint:MINT-8396015(identity) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-8396007(identity) - - - figure legend:f6a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/10/01 2014/10/16 rogid:akVjKfOv4g4nEsGN8E3lQ2vCseQ9606 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 intact-crc:085F2252A28CB9E7|rigid:wfAV7ObdkJfWpTEYXcKFgfu0He0 false binding-associated region:690-807(MINT-8396016)|glutathione s tranferase tag:?-?(MINT-8396018) mutation decreasing interaction:76-76(MINT-8396008)|mutation decreasing interaction:67-67(MINT-8396010)|ha tag:?-?(MINT-8396012) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P62331 uniprotkb:Q02241 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 intact:EBI-306852|uniprotkb:Q8WVP0|ensembl:ENSP00000260363|ensembl:ENSP00000497065|intact:EBI-2558308|uniprotkb:B4E1K0 psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:kif23_human(display_long)|uniprotkb:KIF23(gene name)|psi-mi:KIF23(display_short)|uniprotkb:KNSL5(gene name synonym)|uniprotkb:MKLP1(gene name synonym)|uniprotkb:Mitotic kinesin-like protein 1(gene name synonym)|uniprotkb:Kinesin-like protein 5(gene name synonym) psi-mi:"MI:0096"(pull down) Makyio et al. (2012) doi:10.1038/emboj.2012.89|pubmed:22522702|imex:IM-18769|mint:MINT-8395701 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7832736|mint:MINT-8396027|imex:IM-18769-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-8396029(identity) refseq:NP_004847.2|refseq:NP_612565.1|ensembl:ENSG00000137807(gene)|ensembl:ENST00000260363(transcript)|ensembl:ENST00000647715(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030496"(midbody)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|go:"GO:0000281"(mitotic cytokinesis)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR038105|mint:Q02241|rcsb pdb:3VHX|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-68884|interpro:IPR032384|reactome:R-HSA-983189|ensembl:ENSP00000260363|ensembl:ENST00000352331|ensembl:ENSP00000304978|ensembl:ENSP00000497065|dip:DIP-40359N|mint:MINT-8396037(identity) - - - comment:homomint|comment:mint|figure legend:f6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/10/01 2014/10/16 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 rogid:akVjKfOv4g4nEsGN8E3lQ2vCseQ9606 intact-crc:4062F80365CE70D9|rigid:wfAV7ObdkJfWpTEYXcKFgfu0He0 false mutation increasing interaction:?-?(MINT-8396030)|ha tag:?-?(MINT-8396034) binding-associated region:690-807(MINT-8396040)|glutathione s tranferase tag:?-?(MINT-8396038) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62331 uniprotkb:Q02241 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 intact:EBI-306852|uniprotkb:Q8WVP0|ensembl:ENSP00000260363|ensembl:ENSP00000497065|intact:EBI-2558308|uniprotkb:B4E1K0 psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:kif23_human(display_long)|uniprotkb:KIF23(gene name)|psi-mi:KIF23(display_short)|uniprotkb:KNSL5(gene name synonym)|uniprotkb:MKLP1(gene name synonym)|uniprotkb:Mitotic kinesin-like protein 1(gene name synonym)|uniprotkb:Kinesin-like protein 5(gene name synonym) psi-mi:"MI:0096"(pull down) Makyio et al. (2012) doi:10.1038/emboj.2012.89|pubmed:22522702|imex:IM-18769|mint:MINT-8395701 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7832763|mint:MINT-8396047|imex:IM-18769-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-8396049(identity) refseq:NP_004847.2|refseq:NP_612565.1|ensembl:ENSG00000137807(gene)|ensembl:ENST00000260363(transcript)|ensembl:ENST00000647715(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030496"(midbody)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|go:"GO:0000281"(mitotic cytokinesis)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR038105|mint:Q02241|rcsb pdb:3VHX|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-68884|interpro:IPR032384|reactome:R-HSA-983189|ensembl:ENSP00000260363|ensembl:ENST00000352331|ensembl:ENSP00000304978|ensembl:ENSP00000497065|dip:DIP-40359N|mint:MINT-8396055(identity) - - - comment:homomint|comment:mint|figure legend:f6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/10/01 2014/10/16 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 rogid:akVjKfOv4g4nEsGN8E3lQ2vCseQ9606 intact-crc:A9DB01A256D73F7B|rigid:wfAV7ObdkJfWpTEYXcKFgfu0He0 false ha tag:?-?(MINT-8396052)|mutation decreasing interaction:?-?(MINT-8396050) glutathione s tranferase tag:?-?(MINT-8396058)|binding-associated region:690-807(MINT-8396056) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P62330 uniprotkb:Q02241 intact:EBI-638181|uniprotkb:P26438|ensembl:ENSP00000298316|intact:EBI-2802827|uniprotkb:Q6FGZ2 intact:EBI-306852|uniprotkb:Q8WVP0|ensembl:ENSP00000260363|ensembl:ENSP00000497065|intact:EBI-2558308|uniprotkb:B4E1K0 psi-mi:arf6_human(display_long)|uniprotkb:ARF6(gene name)|psi-mi:ARF6(display_short) psi-mi:kif23_human(display_long)|uniprotkb:KIF23(gene name)|psi-mi:KIF23(display_short)|uniprotkb:KNSL5(gene name synonym)|uniprotkb:MKLP1(gene name synonym)|uniprotkb:Mitotic kinesin-like protein 1(gene name synonym)|uniprotkb:Kinesin-like protein 5(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Makyio et al. (2012) doi:10.1038/emboj.2012.89|pubmed:22522702|imex:IM-18769|mint:MINT-8395701 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7832816|mint:MINT-8395820|imex:IM-18769-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001654.1|ensembl:ENSG00000165527(gene)|ensembl:ENST00000298316(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|rcsb pdb:1E0S|rcsb pdb:2A5D|rcsb pdb:2A5F|rcsb pdb:2A5G|rcsb pdb:2BAO|rcsb pdb:2BAU|rcsb pdb:2J5X|rcsb pdb:2W83|rcsb pdb:3LVQ|rcsb pdb:3LVR|rcsb pdb:3N5C|rcsb pdb:3PCR|rcsb pdb:4FME|rcsb pdb:4KAX|rcsb pdb:6BBP|rcsb pdb:6BBQ|rcsb pdb:6PAU|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8875656|dip:DIP-33352N|mint:MINT-8395822(identity) refseq:NP_004847.2|refseq:NP_612565.1|ensembl:ENSG00000137807(gene)|ensembl:ENST00000260363(transcript)|ensembl:ENST00000647715(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030496"(midbody)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|go:"GO:0000281"(mitotic cytokinesis)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR038105|mint:Q02241|rcsb pdb:3VHX|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-68884|interpro:IPR032384|reactome:R-HSA-983189|ensembl:ENSP00000260363|ensembl:ENST00000352331|ensembl:ENSP00000304978|ensembl:ENSP00000497065|dip:DIP-40359N|mint:MINT-8395828(identity) go:"GO:0030496"(midbody) - - figure legend:f3a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2012/10/01 2014/10/16 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC89606 rogid:akVjKfOv4g4nEsGN8E3lQ2vCseQ9606 intact-crc:9DAC99857E4BFCA7|rigid:FFnlD/KWekO3/pI6rdzjxb1IRTA false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q02241 uniprotkb:P62331 intact:EBI-306852|uniprotkb:Q8WVP0|ensembl:ENSP00000260363|ensembl:ENSP00000497065|intact:EBI-2558308|uniprotkb:B4E1K0 intact:EBI-988682|uniprotkb:P26438|ensembl:ENSMUSP00000055862 psi-mi:kif23_human(display_long)|uniprotkb:KIF23(gene name)|psi-mi:KIF23(display_short)|uniprotkb:KNSL5(gene name synonym)|uniprotkb:MKLP1(gene name synonym)|uniprotkb:Mitotic kinesin-like protein 1(gene name synonym)|uniprotkb:Kinesin-like protein 5(gene name synonym) psi-mi:arf6_mouse(display_long)|uniprotkb:Arf6(gene name)|psi-mi:Arf6(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Makyio et al. (2012) doi:10.1038/emboj.2012.89|pubmed:22522702|imex:IM-18769|mint:MINT-8395701 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7832829|mint:MINT-8395840|imex:IM-18769-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004847.2|refseq:NP_612565.1|ensembl:ENSG00000137807(gene)|ensembl:ENST00000260363(transcript)|ensembl:ENST00000647715(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030496"(midbody)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|go:"GO:0000281"(mitotic cytokinesis)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR038105|mint:Q02241|rcsb pdb:3VHX|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-68884|interpro:IPR032384|reactome:R-HSA-983189|ensembl:ENSP00000260363|ensembl:ENST00000352331|ensembl:ENSP00000304978|ensembl:ENSP00000497065|dip:DIP-40359N|mint:MINT-8395843(identity) refseq:NP_031507.1|ensembl:ENSMUSG00000044147(gene)|ensembl:ENSMUST00000050063(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001889"(liver development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007049"(cell cycle)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033028"(myeloid cell apoptotic process)|go:"GO:0034143"(regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051301"(cell division)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0055037"(recycling endosome)|go:"GO:0006886"(intracellular protein transport)|reactome:R-MMU-8854214|reactome:R-MMU-8856828|reactome:R-MMU-8875656|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090543"(Flemming body)|go:"GO:0097178"(ruffle assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR041838|mint:P62331|rcsb pdb:3VHX|mint:MINT-8395845(identity) go:"GO:0030496"(midbody) - - figure legend:f6c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2012/10/01 2014/10/16 rogid:akVjKfOv4g4nEsGN8E3lQ2vCseQ9606 rogid:c+9TIZ6WGhwZzmFUnkW20tPjlC810090 intact-crc:57666380D88BD92C|rigid:wfAV7ObdkJfWpTEYXcKFgfu0He0 false - mutation disrupting interaction:77-77(MINT-8395851)|green fluorescent protein tag:?-?(MINT-8395849) - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q02241 uniprotkb:Q02241 intact:EBI-306852|uniprotkb:Q8WVP0|ensembl:ENSP00000260363|ensembl:ENSP00000497065|intact:EBI-2558308|uniprotkb:B4E1K0 intact:EBI-306852|uniprotkb:Q8WVP0|ensembl:ENSP00000260363|ensembl:ENSP00000497065|intact:EBI-2558308|uniprotkb:B4E1K0 psi-mi:kif23_human(display_long)|uniprotkb:KIF23(gene name)|psi-mi:KIF23(display_short)|uniprotkb:KNSL5(gene name synonym)|uniprotkb:MKLP1(gene name synonym)|uniprotkb:Mitotic kinesin-like protein 1(gene name synonym)|uniprotkb:Kinesin-like protein 5(gene name synonym) psi-mi:kif23_human(display_long)|uniprotkb:KIF23(gene name)|psi-mi:KIF23(display_short)|uniprotkb:KNSL5(gene name synonym)|uniprotkb:MKLP1(gene name synonym)|uniprotkb:Mitotic kinesin-like protein 1(gene name synonym)|uniprotkb:Kinesin-like protein 5(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Makyio et al. (2012) doi:10.1038/emboj.2012.89|pubmed:22522702|imex:IM-18769|mint:MINT-8395701 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7832858|mint:MINT-8396064|imex:IM-18769-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004847.2|refseq:NP_612565.1|ensembl:ENSG00000137807(gene)|ensembl:ENST00000260363(transcript)|ensembl:ENST00000647715(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030496"(midbody)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|go:"GO:0000281"(mitotic cytokinesis)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR038105|mint:Q02241|rcsb pdb:3VHX|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-68884|interpro:IPR032384|reactome:R-HSA-983189|ensembl:ENSP00000260363|ensembl:ENST00000352331|ensembl:ENSP00000304978|ensembl:ENSP00000497065|dip:DIP-40359N|mint:MINT-8396072(identity) refseq:NP_004847.2|refseq:NP_612565.1|ensembl:ENSG00000137807(gene)|ensembl:ENST00000260363(transcript)|ensembl:ENST00000647715(transcript)|go:"GO:0000022"(mitotic spindle elongation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008017"(microtubule binding)|go:"GO:0030496"(midbody)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0051256"(mitotic spindle midzone assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|go:"GO:0097149"(centralspindlin complex)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|go:"GO:0000281"(mitotic cytokinesis)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR038105|mint:Q02241|rcsb pdb:3VHX|reactome:R-HSA-2132295|reactome:R-HSA-6811434|reactome:R-HSA-68884|interpro:IPR032384|reactome:R-HSA-983189|ensembl:ENSP00000260363|ensembl:ENST00000352331|ensembl:ENSP00000304978|ensembl:ENSP00000497065|dip:DIP-40359N|mint:MINT-8396072(identity) - comment:"Stoichiometry: 2.0" comment:"Stoichiometry: 2.0" figure legend:SF2|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/10/01 2014/10/16 rogid:akVjKfOv4g4nEsGN8E3lQ2vCseQ9606 rogid:akVjKfOv4g4nEsGN8E3lQ2vCseQ9606 intact-crc:0CA2CC0BA9253414|rigid:TK9NEj0mhaxXDB7GL60RVgHNKms false glutathione s tranferase tag:?-?(MINT-8396073)|binding-associated region:690-807(MINT-8396075) glutathione s tranferase tag:?-?(MINT-8396073)|binding-associated region:690-807(MINT-8396075) 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)