#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P14921	uniprotkb:O43711	intact:EBI-913209|uniprotkb:Q14278|uniprotkb:Q16080|ensembl:ENSP00000324578|uniprotkb:Q6N087|uniprotkb:A9UL17|uniprotkb:F5GYX9|uniprotkb:Q96AC5	intact:EBI-3939165|uniprotkb:Q96AD3|ensembl:ENSP00000296921	psi-mi:ets1_human(display_long)|uniprotkb:p54(gene name synonym)|uniprotkb:ETS1(gene name)|psi-mi:ETS1(display_short)|uniprotkb:EWSR2(gene name synonym)	psi-mi:tlx3_human(display_long)|uniprotkb:TLX3(gene name)|psi-mi:TLX3(display_short)|uniprotkb:HOX11L2(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Dadi et al. (2012)	pubmed:22516263|imex:IM-17328	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6097486|imex:IM-17328-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030578"(PML body organization)|go:"GO:0032355"(response to estradiol)|go:"GO:0034616"(response to laminar fluid shear stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044849"(estrous cycle)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048870"(cell motility)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041886|mint:P14921|rcsb pdb:1GVJ|rcsb pdb:2NNY|rcsb pdb:2STT|rcsb pdb:2STW|rcsb pdb:3MFK|rcsb pdb:3RI4|rcsb pdb:3WTS|rcsb pdb:3WTT|rcsb pdb:3WTU|rcsb pdb:3WTV|rcsb pdb:3WTW|rcsb pdb:3WTX|rcsb pdb:3WTY|rcsb pdb:3WTZ|rcsb pdb:3WU0|rcsb pdb:3WU1|rcsb pdb:4L0Y|rcsb pdb:4L0Z|rcsb pdb:4L18|rcsb pdb:4LG0|rcsb pdb:5ZMC|reactome:R-HSA-2559585|refseq:NP_005229.1|ensembl:ENSG00000134954(gene)|ensembl:ENST00000319397(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|refseq:NP_001137292.1|refseq:NP_001155894.1|refseq:NP_001317380.1|refseq:XP_016872803.1|dip:DIP-35183N	ensembl:ENSG00000164438(gene)|ensembl:ENST00000296921(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|refseq:NP_066305.2	-	-	-	figure legend:Fig 3C|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-dnd-41)|taxid:9606("Human DND-41 (T-ALL; type III cortical) cell line")	-	2012/04/24	2014/10/16	rogid:KP3E8/vvVBip6KrkyUpm9poWd/E9606	rogid:TTCEjERZEVADujEiNmARHuHEle49606	intact-crc:C0DC42F7730308B1|rigid:tzEq2UBQYGdDtT2k4XDO62en51U	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P27577	uniprotkb:P31314	intact:EBI-4289053|uniprotkb:Q61403|ensembl:ENSMUSP00000034534	intact:EBI-2820655|uniprotkb:Q9HCA0|uniprotkb:O75699|uniprotkb:Q9UD59|uniprotkb:Q5VXP2|uniprotkb:A1L4G3|ensembl:ENSP00000359215	psi-mi:ets1_mouse(display_long)|uniprotkb:Ets1(gene name)|psi-mi:Ets1(display_short)|uniprotkb:Ets-1(gene name synonym)|uniprotkb:p54(gene name synonym)	psi-mi:tlx1_human(display_long)|uniprotkb:TLX1(gene name)|psi-mi:TLX1(display_short)|uniprotkb:HOX11(gene name synonym)|uniprotkb:TCL3(gene name synonym)|uniprotkb:Homeobox protein Hox-11(gene name synonym)|uniprotkb:Proto-oncogene TCL-3(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Dadi et al. (2012)	pubmed:22516263|imex:IM-17328	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6097351|imex:IM-17328-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035938.2|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030578"(PML body organization)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048870"(cell motility)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041886|rcsb pdb:1K78|rcsb pdb:1K79|rcsb pdb:1K7A|rcsb pdb:1MD0|rcsb pdb:1MDM|rcsb pdb:1R36|rcsb pdb:2JV3|rcsb pdb:2KMD|rcsb pdb:6DA1|rcsb pdb:6DAT|reactome:R-MMU-2559585|go:"GO:0005667"(transcription regulator complex)|ensembl:ENSMUSG00000032035(gene)|ensembl:ENSMUST00000034534(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-41848N	refseq:NP_005512.1|refseq:NP_001182446.1|ensembl:ENSG00000107807(gene)|ensembl:ENST00000370196(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|dip:DIP-155N	-	-	-	figure legend:Fig 3B|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2012/04/24	2014/10/16	rogid:5N3mG6XU77Y0OnF5xeY53Pewa3M10090	rogid:9T87oIC0qC7OWt1ZIdxZhNfA6KA9606	intact-crc:51EDA40064FE8A64|rigid:ckU2RxfU+Zl37GZg0ynn1cTQ/Ns	false	ha tag:?-?|his tag:?-?(IPR000418)	flag tag:?-?|sbp:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P27577	uniprotkb:O43711	intact:EBI-4289053|uniprotkb:Q61403|ensembl:ENSMUSP00000034534	intact:EBI-3939165|uniprotkb:Q96AD3|ensembl:ENSP00000296921	psi-mi:ets1_mouse(display_long)|uniprotkb:Ets1(gene name)|psi-mi:Ets1(display_short)|uniprotkb:Ets-1(gene name synonym)|uniprotkb:p54(gene name synonym)	psi-mi:tlx3_human(display_long)|uniprotkb:TLX3(gene name)|psi-mi:TLX3(display_short)|uniprotkb:HOX11L2(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Dadi et al. (2012)	pubmed:22516263|imex:IM-17328	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6097382|imex:IM-17328-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035938.2|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030578"(PML body organization)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048870"(cell motility)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041886|rcsb pdb:1K78|rcsb pdb:1K79|rcsb pdb:1K7A|rcsb pdb:1MD0|rcsb pdb:1MDM|rcsb pdb:1R36|rcsb pdb:2JV3|rcsb pdb:2KMD|rcsb pdb:6DA1|rcsb pdb:6DAT|reactome:R-MMU-2559585|go:"GO:0005667"(transcription regulator complex)|ensembl:ENSMUSG00000032035(gene)|ensembl:ENSMUST00000034534(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-41848N	ensembl:ENSG00000164438(gene)|ensembl:ENST00000296921(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|refseq:NP_066305.2	-	-	-	figure legend:Fig 3B|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2012/04/24	2014/10/16	rogid:5N3mG6XU77Y0OnF5xeY53Pewa3M10090	rogid:TTCEjERZEVADujEiNmARHuHEle49606	intact-crc:6457C2FB56F53D05|rigid:en2awc/P18QCR+OPtN8Ohkwm42E	false	ha tag:?-?|his tag:?-?(IPR000418)	sbp:?-?|flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P14921	uniprotkb:P31314	intact:EBI-913209|uniprotkb:Q14278|uniprotkb:Q16080|ensembl:ENSP00000324578|uniprotkb:Q6N087|uniprotkb:A9UL17|uniprotkb:F5GYX9|uniprotkb:Q96AC5	intact:EBI-2820655|uniprotkb:Q9HCA0|uniprotkb:O75699|uniprotkb:Q9UD59|uniprotkb:Q5VXP2|uniprotkb:A1L4G3|ensembl:ENSP00000359215	psi-mi:ets1_human(display_long)|uniprotkb:p54(gene name synonym)|uniprotkb:ETS1(gene name)|psi-mi:ETS1(display_short)|uniprotkb:EWSR2(gene name synonym)	psi-mi:tlx1_human(display_long)|uniprotkb:TLX1(gene name)|psi-mi:TLX1(display_short)|uniprotkb:HOX11(gene name synonym)|uniprotkb:TCL3(gene name synonym)|uniprotkb:Homeobox protein Hox-11(gene name synonym)|uniprotkb:Proto-oncogene TCL-3(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Dadi et al. (2012)	pubmed:22516263|imex:IM-17328	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6097438|imex:IM-17328-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030578"(PML body organization)|go:"GO:0032355"(response to estradiol)|go:"GO:0034616"(response to laminar fluid shear stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044849"(estrous cycle)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048870"(cell motility)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041886|mint:P14921|rcsb pdb:1GVJ|rcsb pdb:2NNY|rcsb pdb:2STT|rcsb pdb:2STW|rcsb pdb:3MFK|rcsb pdb:3RI4|rcsb pdb:3WTS|rcsb pdb:3WTT|rcsb pdb:3WTU|rcsb pdb:3WTV|rcsb pdb:3WTW|rcsb pdb:3WTX|rcsb pdb:3WTY|rcsb pdb:3WTZ|rcsb pdb:3WU0|rcsb pdb:3WU1|rcsb pdb:4L0Y|rcsb pdb:4L0Z|rcsb pdb:4L18|rcsb pdb:4LG0|rcsb pdb:5ZMC|reactome:R-HSA-2559585|refseq:NP_005229.1|ensembl:ENSG00000134954(gene)|ensembl:ENST00000319397(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|refseq:NP_001137292.1|refseq:NP_001155894.1|refseq:NP_001317380.1|refseq:XP_016872803.1|dip:DIP-35183N	refseq:NP_005512.1|refseq:NP_001182446.1|ensembl:ENSG00000107807(gene)|ensembl:ENST00000370196(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|dip:DIP-155N	-	-	-	figure legend:Fig 3C|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-all-sil)|taxid:9606("Human ALL-SIL -a  T-ALL (T cell acute lymphoblastic leukemia) cell line")	-	2012/04/24	2014/10/16	rogid:KP3E8/vvVBip6KrkyUpm9poWd/E9606	rogid:9T87oIC0qC7OWt1ZIdxZhNfA6KA9606	intact-crc:202F32D0F6C1C87F|rigid:GHkoQkKzsJXIPAAFOFCy9836dK0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P27577	uniprotkb:P31314	intact:EBI-4289053|uniprotkb:Q61403|ensembl:ENSMUSP00000034534	intact:EBI-2820655|uniprotkb:Q9HCA0|uniprotkb:O75699|uniprotkb:Q9UD59|uniprotkb:Q5VXP2|uniprotkb:A1L4G3|ensembl:ENSP00000359215	psi-mi:ets1_mouse(display_long)|uniprotkb:Ets1(gene name)|psi-mi:Ets1(display_short)|uniprotkb:Ets-1(gene name synonym)|uniprotkb:p54(gene name synonym)	psi-mi:tlx1_human(display_long)|uniprotkb:TLX1(gene name)|psi-mi:TLX1(display_short)|uniprotkb:HOX11(gene name synonym)|uniprotkb:TCL3(gene name synonym)|uniprotkb:Homeobox protein Hox-11(gene name synonym)|uniprotkb:Proto-oncogene TCL-3(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Dadi et al. (2012)	pubmed:22516263|imex:IM-17328	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6097278|imex:IM-17328-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035938.2|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030578"(PML body organization)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048870"(cell motility)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041886|rcsb pdb:1K78|rcsb pdb:1K79|rcsb pdb:1K7A|rcsb pdb:1MD0|rcsb pdb:1MDM|rcsb pdb:1R36|rcsb pdb:2JV3|rcsb pdb:2KMD|rcsb pdb:6DA1|rcsb pdb:6DAT|reactome:R-MMU-2559585|go:"GO:0005667"(transcription regulator complex)|ensembl:ENSMUSG00000032035(gene)|ensembl:ENSMUST00000034534(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-41848N	refseq:NP_005512.1|refseq:NP_001182446.1|ensembl:ENSG00000107807(gene)|ensembl:ENST00000370196(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|dip:DIP-155N	-	-	-	figure legend:Fig 3A|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/24	2014/10/16	rogid:5N3mG6XU77Y0OnF5xeY53Pewa3M10090	rogid:9T87oIC0qC7OWt1ZIdxZhNfA6KA9606	intact-crc:E36EEFBD59A77AC3|rigid:ckU2RxfU+Zl37GZg0ynn1cTQ/Ns	false	necessary binding region:335..335-415..415(IPR000418)|35s radiolabel:?-?	necessary binding region:201..201-260..260(IPR001356)|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P27577	uniprotkb:O43711	intact:EBI-4289053|uniprotkb:Q61403|ensembl:ENSMUSP00000034534	intact:EBI-3939165|uniprotkb:Q96AD3|ensembl:ENSP00000296921	psi-mi:ets1_mouse(display_long)|uniprotkb:Ets1(gene name)|psi-mi:Ets1(display_short)|uniprotkb:Ets-1(gene name synonym)|uniprotkb:p54(gene name synonym)	psi-mi:tlx3_human(display_long)|uniprotkb:TLX3(gene name)|psi-mi:TLX3(display_short)|uniprotkb:HOX11L2(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Dadi et al. (2012)	pubmed:22516263|imex:IM-17328	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6097293|imex:IM-17328-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035938.2|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0030154"(cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030578"(PML body organization)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048870"(cell motility)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041886|rcsb pdb:1K78|rcsb pdb:1K79|rcsb pdb:1K7A|rcsb pdb:1MD0|rcsb pdb:1MDM|rcsb pdb:1R36|rcsb pdb:2JV3|rcsb pdb:2KMD|rcsb pdb:6DA1|rcsb pdb:6DAT|reactome:R-MMU-2559585|go:"GO:0005667"(transcription regulator complex)|ensembl:ENSMUSG00000032035(gene)|ensembl:ENSMUST00000034534(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002376"(immune system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-41848N	ensembl:ENSG00000164438(gene)|ensembl:ENST00000296921(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|refseq:NP_066305.2	-	-	-	figure legend:Fig 3A|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/24	2014/10/16	rogid:5N3mG6XU77Y0OnF5xeY53Pewa3M10090	rogid:TTCEjERZEVADujEiNmARHuHEle49606	intact-crc:945E99D97172F417|rigid:en2awc/P18QCR+OPtN8Ohkwm42E	false	35s radiolabel:?-?|necessary binding region:335..335-415..415(IPR000418)	glutathione s tranferase tag:?-?|necessary binding region:166..166-225..225(IPR001356)	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P14921	uniprotkb:O43711	intact:EBI-913209|uniprotkb:Q14278|uniprotkb:Q16080|ensembl:ENSP00000324578|uniprotkb:Q6N087|uniprotkb:A9UL17|uniprotkb:F5GYX9|uniprotkb:Q96AC5	intact:EBI-3939165|uniprotkb:Q96AD3|ensembl:ENSP00000296921	psi-mi:ets1_human(display_long)|uniprotkb:p54(gene name synonym)|uniprotkb:ETS1(gene name)|psi-mi:ETS1(display_short)|uniprotkb:EWSR2(gene name synonym)	psi-mi:tlx3_human(display_long)|uniprotkb:TLX3(gene name)|psi-mi:TLX3(display_short)|uniprotkb:HOX11L2(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Dadi et al. (2012)	pubmed:22516263|imex:IM-17328	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6101392|imex:IM-17328-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030578"(PML body organization)|go:"GO:0032355"(response to estradiol)|go:"GO:0034616"(response to laminar fluid shear stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044849"(estrous cycle)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048870"(cell motility)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041886|mint:P14921|rcsb pdb:1GVJ|rcsb pdb:2NNY|rcsb pdb:2STT|rcsb pdb:2STW|rcsb pdb:3MFK|rcsb pdb:3RI4|rcsb pdb:3WTS|rcsb pdb:3WTT|rcsb pdb:3WTU|rcsb pdb:3WTV|rcsb pdb:3WTW|rcsb pdb:3WTX|rcsb pdb:3WTY|rcsb pdb:3WTZ|rcsb pdb:3WU0|rcsb pdb:3WU1|rcsb pdb:4L0Y|rcsb pdb:4L0Z|rcsb pdb:4L18|rcsb pdb:4LG0|rcsb pdb:5ZMC|reactome:R-HSA-2559585|refseq:NP_005229.1|ensembl:ENSG00000134954(gene)|ensembl:ENST00000319397(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|refseq:NP_001137292.1|refseq:NP_001155894.1|refseq:NP_001317380.1|refseq:XP_016872803.1|dip:DIP-35183N	ensembl:ENSG00000164438(gene)|ensembl:ENST00000296921(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|refseq:NP_066305.2	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig 4C|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t-all)|taxid:9606(Human-T-cell acute lymphoblastic leukemia cells)	-	2012/04/24	2014/10/16	rogid:KP3E8/vvVBip6KrkyUpm9poWd/E9606	rogid:TTCEjERZEVADujEiNmARHuHEle49606	intact-crc:8852DBC490C7D132|rigid:tzEq2UBQYGdDtT2k4XDO62en51U	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P31314	uniprotkb:P14921	intact:EBI-2820655|uniprotkb:Q9HCA0|uniprotkb:O75699|uniprotkb:Q9UD59|uniprotkb:Q5VXP2|uniprotkb:A1L4G3|ensembl:ENSP00000359215	intact:EBI-913209|uniprotkb:Q14278|uniprotkb:Q16080|ensembl:ENSP00000324578|uniprotkb:Q6N087|uniprotkb:A9UL17|uniprotkb:F5GYX9|uniprotkb:Q96AC5	psi-mi:tlx1_human(display_long)|uniprotkb:TLX1(gene name)|psi-mi:TLX1(display_short)|uniprotkb:HOX11(gene name synonym)|uniprotkb:TCL3(gene name synonym)|uniprotkb:Homeobox protein Hox-11(gene name synonym)|uniprotkb:Proto-oncogene TCL-3(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 3(gene name synonym)	psi-mi:ets1_human(display_long)|uniprotkb:p54(gene name synonym)|uniprotkb:ETS1(gene name)|psi-mi:ETS1(display_short)|uniprotkb:EWSR2(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Dadi et al. (2012)	pubmed:22516263|imex:IM-17328	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6100078|imex:IM-17328-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005512.1|refseq:NP_001182446.1|ensembl:ENSG00000107807(gene)|ensembl:ENST00000370196(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|dip:DIP-155N	go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030578"(PML body organization)|go:"GO:0032355"(response to estradiol)|go:"GO:0034616"(response to laminar fluid shear stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044849"(estrous cycle)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048870"(cell motility)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041886|mint:P14921|rcsb pdb:1GVJ|rcsb pdb:2NNY|rcsb pdb:2STT|rcsb pdb:2STW|rcsb pdb:3MFK|rcsb pdb:3RI4|rcsb pdb:3WTS|rcsb pdb:3WTT|rcsb pdb:3WTU|rcsb pdb:3WTV|rcsb pdb:3WTW|rcsb pdb:3WTX|rcsb pdb:3WTY|rcsb pdb:3WTZ|rcsb pdb:3WU0|rcsb pdb:3WU1|rcsb pdb:4L0Y|rcsb pdb:4L0Z|rcsb pdb:4L18|rcsb pdb:4LG0|rcsb pdb:5ZMC|reactome:R-HSA-2559585|refseq:NP_005229.1|ensembl:ENSG00000134954(gene)|ensembl:ENST00000319397(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|refseq:NP_001137292.1|refseq:NP_001155894.1|refseq:NP_001317380.1|refseq:XP_016872803.1|dip:DIP-35183N	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig 4C|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-t-all)|taxid:9606(Human-T-cell acute lymphoblastic leukemia cells)	-	2012/04/24	2014/10/16	rogid:9T87oIC0qC7OWt1ZIdxZhNfA6KA9606	rogid:KP3E8/vvVBip6KrkyUpm9poWd/E9606	intact-crc:C4868649AF60A241|rigid:GHkoQkKzsJXIPAAFOFCy9836dK0	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P31314	uniprotkb:P14921	intact:EBI-2820655|uniprotkb:Q9HCA0|uniprotkb:O75699|uniprotkb:Q9UD59|uniprotkb:Q5VXP2|uniprotkb:A1L4G3|ensembl:ENSP00000359215	intact:EBI-913209|uniprotkb:Q14278|uniprotkb:Q16080|ensembl:ENSP00000324578|uniprotkb:Q6N087|uniprotkb:A9UL17|uniprotkb:F5GYX9|uniprotkb:Q96AC5	psi-mi:tlx1_human(display_long)|uniprotkb:TLX1(gene name)|psi-mi:TLX1(display_short)|uniprotkb:HOX11(gene name synonym)|uniprotkb:TCL3(gene name synonym)|uniprotkb:Homeobox protein Hox-11(gene name synonym)|uniprotkb:Proto-oncogene TCL-3(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 3(gene name synonym)	psi-mi:ets1_human(display_long)|uniprotkb:p54(gene name synonym)|uniprotkb:ETS1(gene name)|psi-mi:ETS1(display_short)|uniprotkb:EWSR2(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Dadi et al. (2012)	pubmed:22516263|imex:IM-17328	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6097529|imex:IM-17328-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005512.1|refseq:NP_001182446.1|ensembl:ENSG00000107807(gene)|ensembl:ENST00000370196(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|dip:DIP-155N	go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030578"(PML body organization)|go:"GO:0032355"(response to estradiol)|go:"GO:0034616"(response to laminar fluid shear stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044849"(estrous cycle)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048870"(cell motility)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041886|mint:P14921|rcsb pdb:1GVJ|rcsb pdb:2NNY|rcsb pdb:2STT|rcsb pdb:2STW|rcsb pdb:3MFK|rcsb pdb:3RI4|rcsb pdb:3WTS|rcsb pdb:3WTT|rcsb pdb:3WTU|rcsb pdb:3WTV|rcsb pdb:3WTW|rcsb pdb:3WTX|rcsb pdb:3WTY|rcsb pdb:3WTZ|rcsb pdb:3WU0|rcsb pdb:3WU1|rcsb pdb:4L0Y|rcsb pdb:4L0Z|rcsb pdb:4L18|rcsb pdb:4LG0|rcsb pdb:5ZMC|reactome:R-HSA-2559585|refseq:NP_005229.1|ensembl:ENSG00000134954(gene)|ensembl:ENST00000319397(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|refseq:NP_001137292.1|refseq:NP_001155894.1|refseq:NP_001317380.1|refseq:XP_016872803.1|dip:DIP-35183N	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig 4C/D|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-all-sil)|taxid:9606("Human ALL-SIL -a  T-ALL (T cell acute lymphoblastic leukemia) cell line")	-	2012/04/24	2014/10/16	rogid:9T87oIC0qC7OWt1ZIdxZhNfA6KA9606	rogid:KP3E8/vvVBip6KrkyUpm9poWd/E9606	intact-crc:4E3B0D8A2F0A7E51|rigid:GHkoQkKzsJXIPAAFOFCy9836dK0	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:O43711	uniprotkb:P14921	intact:EBI-3939165|uniprotkb:Q96AD3|ensembl:ENSP00000296921	intact:EBI-913209|uniprotkb:Q14278|uniprotkb:Q16080|ensembl:ENSP00000324578|uniprotkb:Q6N087|uniprotkb:A9UL17|uniprotkb:F5GYX9|uniprotkb:Q96AC5	psi-mi:tlx3_human(display_long)|uniprotkb:TLX3(gene name)|psi-mi:TLX3(display_short)|uniprotkb:HOX11L2(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)	psi-mi:ets1_human(display_long)|uniprotkb:p54(gene name synonym)|uniprotkb:ETS1(gene name)|psi-mi:ETS1(display_short)|uniprotkb:EWSR2(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Dadi et al. (2012)	pubmed:22516263|imex:IM-17328	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6100601|imex:IM-17328-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000164438(gene)|ensembl:ENST00000296921(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|refseq:NP_066305.2	go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030578"(PML body organization)|go:"GO:0032355"(response to estradiol)|go:"GO:0034616"(response to laminar fluid shear stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044849"(estrous cycle)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048870"(cell motility)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041886|mint:P14921|rcsb pdb:1GVJ|rcsb pdb:2NNY|rcsb pdb:2STT|rcsb pdb:2STW|rcsb pdb:3MFK|rcsb pdb:3RI4|rcsb pdb:3WTS|rcsb pdb:3WTT|rcsb pdb:3WTU|rcsb pdb:3WTV|rcsb pdb:3WTW|rcsb pdb:3WTX|rcsb pdb:3WTY|rcsb pdb:3WTZ|rcsb pdb:3WU0|rcsb pdb:3WU1|rcsb pdb:4L0Y|rcsb pdb:4L0Z|rcsb pdb:4L18|rcsb pdb:4LG0|rcsb pdb:5ZMC|reactome:R-HSA-2559585|refseq:NP_005229.1|ensembl:ENSG00000134954(gene)|ensembl:ENST00000319397(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|refseq:NP_001137292.1|refseq:NP_001155894.1|refseq:NP_001317380.1|refseq:XP_016872803.1|dip:DIP-35183N	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig 4C|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-dnd-41)|taxid:9606("Human DND-41 (T-ALL; type III cortical) cell line")	-	2012/04/24	2014/10/16	rogid:TTCEjERZEVADujEiNmARHuHEle49606	rogid:KP3E8/vvVBip6KrkyUpm9poWd/E9606	intact-crc:7A34DA74E2115101|rigid:tzEq2UBQYGdDtT2k4XDO62en51U	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
intact:EBI-6101434	uniprotkb:O43763	-	intact:EBI-6101484|ensembl:ENSP00000233638|uniprotkb:Q9UD56|uniprotkb:Q9UQ48	psi-mi:tca-alpha_enhancer_ebs(display_short)|psi-mi:EBI-6101434(display_long)	psi-mi:tlx2_human(display_long)|uniprotkb:TLX2(gene name)|psi-mi:TLX2(display_short)|uniprotkb:HOX11L1(gene name synonym)|uniprotkb:NCX(gene name synonym)|uniprotkb:Homeobox protein Hox-11L1(gene name synonym)|uniprotkb:Neural crest homeobox protein(gene name synonym)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Dadi et al. (2012)	pubmed:22516263|imex:IM-17328	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6101470|imex:IM-17328-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000115297(gene)|ensembl:ENST00000233638(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048484"(enteric nervous system development)|go:"GO:0048513"(animal organ development)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|rcsb pdb:3A03|refseq:NP_057254.1	-	-	-	figure legend:Fig 5A/B|agonist:"The addition of TLX1 (lanes 2–4) or TLX3 (lanes 5–7) to ETS1 and EBS produced a dose-dependent  \"super-shifted\" complex."|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/24	2014/10/16	-	rogid:YneY/Po6lBxICmdUuIP+4R8qJzI9606	intact-crc:8F253262481830F9	false	32p radiolabel:?-?	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-6101434	uniprotkb:P13474	-	intact:EBI-6112253	psi-mi:tca-alpha_enhancer_ebs(display_short)|psi-mi:EBI-6101434(display_long)	psi-mi:ets1a_chick(display_long)|uniprotkb:ETS1(gene name)|psi-mi:ETS1(display_short)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Dadi et al. (2012)	pubmed:22516263|imex:IM-17328	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6101470|imex:IM-17328-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0010595"(positive regulation of endothelial cell migration)|interpro:IPR036388|interpro:IPR036390|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|refseq:NP_990629.2|interpro:IPR041886	-	-	-	figure legend:Fig 5A/B|agonist:"The addition of TLX1 (lanes 2–4) or TLX3 (lanes 5–7) to ETS1 and EBS produced a dose-dependent  \"super-shifted\" complex."|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/24	2014/10/16	-	rogid:7QQNTSgn4PuTdJOTZPnD37zQJWo9031	intact-crc:8F253262481830F9	false	32p radiolabel:?-?	his tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-6101434	uniprotkb:P13474	-	intact:EBI-6112253	psi-mi:tca-alpha_enhancer_ebs(display_short)|psi-mi:EBI-6101434(display_long)	psi-mi:ets1a_chick(display_long)|uniprotkb:ETS1(gene name)|psi-mi:ETS1(display_short)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Dadi et al. (2012)	pubmed:22516263|imex:IM-17328	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6101453|imex:IM-17328-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0010595"(positive regulation of endothelial cell migration)|interpro:IPR036388|interpro:IPR036390|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|refseq:NP_990629.2|interpro:IPR041886	-	-	-	figure legend:Fig 5A/B|agonist:"The addition of TLX1 (lanes 2–4) or TLX3 (lanes 5–7) to ETS1 and EBS produced a dose-dependent  \"super-shifted\" complex."|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/24	2014/10/16	-	rogid:7QQNTSgn4PuTdJOTZPnD37zQJWo9031	intact-crc:6E736AD0E44A51D6	false	32p radiolabel:?-?	his tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-6101434	uniprotkb:P31314	-	intact:EBI-2820655|uniprotkb:Q9HCA0|uniprotkb:O75699|uniprotkb:Q9UD59|uniprotkb:Q5VXP2|uniprotkb:A1L4G3|ensembl:ENSP00000359215	psi-mi:tca-alpha_enhancer_ebs(display_short)|psi-mi:EBI-6101434(display_long)	psi-mi:tlx1_human(display_long)|uniprotkb:TLX1(gene name)|psi-mi:TLX1(display_short)|uniprotkb:HOX11(gene name synonym)|uniprotkb:TCL3(gene name synonym)|uniprotkb:Homeobox protein Hox-11(gene name synonym)|uniprotkb:Proto-oncogene TCL-3(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 3(gene name synonym)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Dadi et al. (2012)	pubmed:22516263|imex:IM-17328	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6101453|imex:IM-17328-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005512.1|refseq:NP_001182446.1|ensembl:ENSG00000107807(gene)|ensembl:ENST00000370196(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|dip:DIP-155N	-	-	-	figure legend:Fig 5A/B|agonist:"The addition of TLX1 (lanes 2–4) or TLX3 (lanes 5–7) to ETS1 and EBS produced a dose-dependent  \"super-shifted\" complex."|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/24	2014/10/16	-	rogid:9T87oIC0qC7OWt1ZIdxZhNfA6KA9606	intact-crc:6E736AD0E44A51D6	false	32p radiolabel:?-?	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-6101434	uniprotkb:P13474	-	intact:EBI-6112253	psi-mi:tca-alpha_enhancer_ebs(display_short)|psi-mi:EBI-6101434(display_long)	psi-mi:ets1a_chick(display_long)|uniprotkb:ETS1(gene name)|psi-mi:ETS1(display_short)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Dadi et al. (2012)	pubmed:22516263|imex:IM-17328	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6101444|imex:IM-17328-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0010595"(positive regulation of endothelial cell migration)|interpro:IPR036388|interpro:IPR036390|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|refseq:NP_990629.2|interpro:IPR041886	-	-	-	figure legend:Fig 5A/B|agonist:"The addition of TLX1 (lanes 2–4) or TLX3 (lanes 5–7) to ETS1 and EBS produced a dose-dependent  \"super-shifted\" complex."|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/04/24	2014/10/16	-	rogid:7QQNTSgn4PuTdJOTZPnD37zQJWo9031	intact-crc:EA4C1ED3FA13529F	false	32p radiolabel:?-?	his tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-6101576	uniprotkb:O43711	-	intact:EBI-3939165|uniprotkb:Q96AD3|ensembl:ENSP00000296921	psi-mi:tcr-alpha_enhancer(display_short)|psi-mi:EBI-6101576(display_long)	psi-mi:tlx3_human(display_long)|uniprotkb:TLX3(gene name)|psi-mi:TLX3(display_short)|uniprotkb:HOX11L2(gene name synonym)|uniprotkb:Homeobox protein Hox-11L2(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Dadi et al. (2012)	pubmed:22516263|imex:IM-17328	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6101613|imex:IM-17328-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000164438(gene)|ensembl:ENST00000296921(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048513"(animal organ development)|go:"GO:0048665"(neuron fate specification)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|refseq:NP_066305.2	-	comment:Sequence given is from the Human TCR-alpha minimal enhancer - Giese at al, Genes and Development. 1995.	-	figure legend:Fig 5 C/D|comment:Knockdown of ETS1 reduced Eα-binding by both ETS1 and TLX1/TLX3.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-dnd-41)|taxid:9606("Human DND-41 (T-ALL; type III cortical) cell line")	-	2012/04/24	2014/10/16	-	rogid:TTCEjERZEVADujEiNmARHuHEle49606	intact-crc:CEBE9F4590E7E4F7	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:P14921	intact:EBI-6101576	intact:EBI-913209|uniprotkb:Q14278|uniprotkb:Q16080|ensembl:ENSP00000324578|uniprotkb:Q6N087|uniprotkb:A9UL17|uniprotkb:F5GYX9|uniprotkb:Q96AC5	-	psi-mi:ets1_human(display_long)|uniprotkb:p54(gene name synonym)|uniprotkb:ETS1(gene name)|psi-mi:ETS1(display_short)|uniprotkb:EWSR2(gene name synonym)	psi-mi:tcr-alpha_enhancer(display_short)|psi-mi:EBI-6101576(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Dadi et al. (2012)	pubmed:22516263|imex:IM-17328	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6101648|imex:IM-17328-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0319"(deoxyribonucleic acid)	go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030578"(PML body organization)|go:"GO:0032355"(response to estradiol)|go:"GO:0034616"(response to laminar fluid shear stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044849"(estrous cycle)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048870"(cell motility)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041886|mint:P14921|rcsb pdb:1GVJ|rcsb pdb:2NNY|rcsb pdb:2STT|rcsb pdb:2STW|rcsb pdb:3MFK|rcsb pdb:3RI4|rcsb pdb:3WTS|rcsb pdb:3WTT|rcsb pdb:3WTU|rcsb pdb:3WTV|rcsb pdb:3WTW|rcsb pdb:3WTX|rcsb pdb:3WTY|rcsb pdb:3WTZ|rcsb pdb:3WU0|rcsb pdb:3WU1|rcsb pdb:4L0Y|rcsb pdb:4L0Z|rcsb pdb:4L18|rcsb pdb:4LG0|rcsb pdb:5ZMC|reactome:R-HSA-2559585|refseq:NP_005229.1|ensembl:ENSG00000134954(gene)|ensembl:ENST00000319397(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|refseq:NP_001137292.1|refseq:NP_001155894.1|refseq:NP_001317380.1|refseq:XP_016872803.1|dip:DIP-35183N	-	-	-	comment:Sequence given is from the Human TCR-alpha minimal enhancer - Giese at al, Genes and Development. 1995.	figure legend:Fig 5 C/D|comment:Knockdown of ETS1 reduced Eα-binding by both ETS1 and TLX1/TLX3.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-dnd-41)|taxid:9606("Human DND-41 (T-ALL; type III cortical) cell line")	-	2012/04/24	2014/10/16	rogid:KP3E8/vvVBip6KrkyUpm9poWd/E9606	-	intact-crc:07CB41A3798E182B	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:P14921	intact:EBI-6101576	intact:EBI-913209|uniprotkb:Q14278|uniprotkb:Q16080|ensembl:ENSP00000324578|uniprotkb:Q6N087|uniprotkb:A9UL17|uniprotkb:F5GYX9|uniprotkb:Q96AC5	-	psi-mi:ets1_human(display_long)|uniprotkb:p54(gene name synonym)|uniprotkb:ETS1(gene name)|psi-mi:ETS1(display_short)|uniprotkb:EWSR2(gene name synonym)	psi-mi:tcr-alpha_enhancer(display_short)|psi-mi:EBI-6101576(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Dadi et al. (2012)	pubmed:22516263|imex:IM-17328	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6101579|imex:IM-17328-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0319"(deoxyribonucleic acid)	go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030578"(PML body organization)|go:"GO:0032355"(response to estradiol)|go:"GO:0034616"(response to laminar fluid shear stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044849"(estrous cycle)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048870"(cell motility)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000418(Ets)|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR016311(Transforming factor C-ets)|interpro:IPR036388|interpro:IPR036390|interpro:IPR041886|mint:P14921|rcsb pdb:1GVJ|rcsb pdb:2NNY|rcsb pdb:2STT|rcsb pdb:2STW|rcsb pdb:3MFK|rcsb pdb:3RI4|rcsb pdb:3WTS|rcsb pdb:3WTT|rcsb pdb:3WTU|rcsb pdb:3WTV|rcsb pdb:3WTW|rcsb pdb:3WTX|rcsb pdb:3WTY|rcsb pdb:3WTZ|rcsb pdb:3WU0|rcsb pdb:3WU1|rcsb pdb:4L0Y|rcsb pdb:4L0Z|rcsb pdb:4L18|rcsb pdb:4LG0|rcsb pdb:5ZMC|reactome:R-HSA-2559585|refseq:NP_005229.1|ensembl:ENSG00000134954(gene)|ensembl:ENST00000319397(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|refseq:NP_001137292.1|refseq:NP_001155894.1|refseq:NP_001317380.1|refseq:XP_016872803.1|dip:DIP-35183N	-	-	-	comment:Sequence given is from the Human TCR-alpha minimal enhancer - Giese at al, Genes and Development. 1995.	figure legend:Fig 5 C/D|comment:Knockdown of ETS1 reduced Eα-binding by both ETS1 and TLX1/TLX3.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-all-sil)|taxid:9606("Human ALL-SIL -a  T-ALL (T cell acute lymphoblastic leukemia) cell line")	-	2012/04/24	2014/10/16	rogid:KP3E8/vvVBip6KrkyUpm9poWd/E9606	-	intact-crc:248A65E69176F73F	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
intact:EBI-6101576	uniprotkb:P31314	-	intact:EBI-2820655|uniprotkb:Q9HCA0|uniprotkb:O75699|uniprotkb:Q9UD59|uniprotkb:Q5VXP2|uniprotkb:A1L4G3|ensembl:ENSP00000359215	psi-mi:tcr-alpha_enhancer(display_short)|psi-mi:EBI-6101576(display_long)	psi-mi:tlx1_human(display_long)|uniprotkb:TLX1(gene name)|psi-mi:TLX1(display_short)|uniprotkb:HOX11(gene name synonym)|uniprotkb:TCL3(gene name synonym)|uniprotkb:Homeobox protein Hox-11(gene name synonym)|uniprotkb:Proto-oncogene TCL-3(gene name synonym)|uniprotkb:T-cell leukemia/lymphoma protein 3(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Dadi et al. (2012)	pubmed:22516263|imex:IM-17328	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6101617|imex:IM-17328-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005512.1|refseq:NP_001182446.1|ensembl:ENSG00000107807(gene)|ensembl:ENST00000370196(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479|interpro:IPR042247|dip:DIP-155N	-	comment:Sequence given is from the Human TCR-alpha minimal enhancer - Giese at al, Genes and Development. 1995.	-	figure legend:Fig 5 C/D|comment:Knockdown of ETS1 reduced Eα-binding by both ETS1 and TLX1/TLX3.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-all-sil)|taxid:9606("Human ALL-SIL -a  T-ALL (T cell acute lymphoblastic leukemia) cell line")	-	2012/04/24	2014/10/16	-	rogid:9T87oIC0qC7OWt1ZIdxZhNfA6KA9606	intact-crc:58E9770CC298154E	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)