#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q5I0H3 uniprotkb:P42260 intact:EBI-7253100|intact:MINT-4651872|ensembl:ENSRNOP00000022048 intact:EBI-7809795|ensembl:ENSRNOP00000068172|intact:MINT-8359884 psi-mi:sumo1_rat(display_long)|uniprotkb:Sumo1(gene name)|psi-mi:Sumo1(display_short) psi-mi:grik2_rat(display_long)|uniprotkb:Grik2(gene name)|psi-mi:Grik2(display_short)|uniprotkb:Glur6(gene name synonym)|uniprotkb:Glutamate receptor 6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhu et al. (2012) pubmed:22483987|mint:MINT-8359886 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7809876|mint:MINT-8359893 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1306919|refseq:NP_001009672.1|ensembl:ENSRNOG00000016133(gene)|ensembl:ENSRNOT00000022047(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0030578"(PML body organization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034605"(cellular response to heat)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045202"(synapse)|go:"GO:0045759"(negative regulation of action potential)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0090204"(protein localization to nuclear pore)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:Q5I0H3|reactome:R-RNO-3065676|reactome:R-RNO-3065678|reactome:R-RNO-3065679|reactome:R-RNO-3108214|reactome:R-RNO-3108232|reactome:R-RNO-3232118|reactome:R-RNO-3232142|reactome:R-RNO-3899300|reactome:R-RNO-4085377|reactome:R-RNO-4090294|reactome:R-RNO-4551638|reactome:R-RNO-4570464|reactome:R-RNO-4615885|reactome:R-RNO-4655427|reactome:R-RNO-4755510|reactome:R-RNO-5693565|reactome:R-RNO-5693571|reactome:R-RNO-5693607|reactome:R-RNO-5696395|reactome:R-RNO-69473|reactome:R-RNO-877312|reactome:R-RNO-8866904|reactome:R-RNO-9615933|dip:DIP-46501N|mint:MINT-8359894(identity)|uniprotkb:Q5I0H3(original identifier) ensembl:ENSRNOG00000000368(gene)|ensembl:ENSRNOT00000076234(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005234"(extracellularly glutamate-gated ion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015277"(kainate selective glutamate receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032983"(kainate selective glutamate receptor complex)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0043204"(perikaryon)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051967"(negative regulation of synaptic transmission, glutamatergic)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:0120169"(detection of cold stimulus involved in thermoception)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:1S50|rcsb pdb:1S7Y|rcsb pdb:1S9T|rcsb pdb:1SD3|rcsb pdb:1TT1|rcsb pdb:1YAE|rcsb pdb:2I0B|rcsb pdb:2I0C|rcsb pdb:2XXR|rcsb pdb:2XXT|rcsb pdb:2XXU|rcsb pdb:2XXV|rcsb pdb:2XXW|rcsb pdb:2XXX|rcsb pdb:2XXY|rcsb pdb:3G3F|rcsb pdb:3G3G|rcsb pdb:3G3H|rcsb pdb:3G3I|rcsb pdb:3G3J|rcsb pdb:3G3K|rcsb pdb:3H6G|rcsb pdb:3H6H|rcsb pdb:3QLT|rcsb pdb:3QLU|rcsb pdb:3QLV|rcsb pdb:4BDL|rcsb pdb:4BDM|rcsb pdb:4BDN|rcsb pdb:4BDO|rcsb pdb:4BDQ|rcsb pdb:4BDR|rcsb pdb:4H8I|rcsb pdb:4UQQ|rcsb pdb:5CMK|rcsb pdb:5CMM|rcsb pdb:5KUF|rcsb pdb:5KUH|rcsb pdb:7KS0|rcsb pdb:7KS3|reactome:R-RNO-451307|reactome:R-RNO-451308|refseq:NP_062182.1|rgd:2733|dip:DIP-29256N|mint:MINT-8359897(identity)|uniprotkb:P42260(original identifier) - comment:mint|function:Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4 comment:mint comment:mint|figure legend:F1B f1c|full coverage: taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain) - 2012/03/23 2014/10/16 rogid:mflrn+v4fHL8UdmLodfZBZA6eAQ10116 rogid:0Eh9oL6GX10ePstSVMv0PpRnFWQ10116 intact-crc:C0EA73CE0A5B42ED|rigid:PGpL1DSJfRRgGdYeS5QR0dDAN5Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:P42260 uniprotkb:Q66HA1 intact:EBI-7809795|ensembl:ENSRNOP00000068172|intact:MINT-8359884 intact:EBI-4279420|uniprotkb:Q80YF1|ensembl:ENSRNOP00000028185 psi-mi:grik2_rat(display_long)|uniprotkb:Grik2(gene name)|psi-mi:Grik2(display_short)|uniprotkb:Glur6(gene name synonym)|uniprotkb:Glutamate receptor 6(gene name synonym) psi-mi:m3k11_rat(display_long)|uniprotkb:Map3k11(gene name)|psi-mi:Map3k11(display_short)|uniprotkb:Mlk3(gene name synonym)|uniprotkb:Mixed lineage kinase 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhu et al. (2012) pubmed:22483987|mint:MINT-8359886 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7809898|mint:MINT-8359972 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000000368(gene)|ensembl:ENSRNOT00000076234(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005234"(extracellularly glutamate-gated ion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015277"(kainate selective glutamate receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032983"(kainate selective glutamate receptor complex)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0043204"(perikaryon)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051967"(negative regulation of synaptic transmission, glutamatergic)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:0120169"(detection of cold stimulus involved in thermoception)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:1S50|rcsb pdb:1S7Y|rcsb pdb:1S9T|rcsb pdb:1SD3|rcsb pdb:1TT1|rcsb pdb:1YAE|rcsb pdb:2I0B|rcsb pdb:2I0C|rcsb pdb:2XXR|rcsb pdb:2XXT|rcsb pdb:2XXU|rcsb pdb:2XXV|rcsb pdb:2XXW|rcsb pdb:2XXX|rcsb pdb:2XXY|rcsb pdb:3G3F|rcsb pdb:3G3G|rcsb pdb:3G3H|rcsb pdb:3G3I|rcsb pdb:3G3J|rcsb pdb:3G3K|rcsb pdb:3H6G|rcsb pdb:3H6H|rcsb pdb:3QLT|rcsb pdb:3QLU|rcsb pdb:3QLV|rcsb pdb:4BDL|rcsb pdb:4BDM|rcsb pdb:4BDN|rcsb pdb:4BDO|rcsb pdb:4BDQ|rcsb pdb:4BDR|rcsb pdb:4H8I|rcsb pdb:4UQQ|rcsb pdb:5CMK|rcsb pdb:5CMM|rcsb pdb:5KUF|rcsb pdb:5KUH|rcsb pdb:7KS0|rcsb pdb:7KS3|reactome:R-RNO-451307|reactome:R-RNO-451308|refseq:NP_062182.1|rgd:2733|dip:DIP-29256N|mint:MINT-8359977(identity)|uniprotkb:P42260(original identifier) rgd:1359261|refseq:NP_001013168.1|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044843"(cell cycle G1/S phase transition)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016231(Mitogen-activated protein kinase kinase kinase, 9/10/11)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035779|interpro:IPR036028|reactome:R-RNO-5673000|reactome:R-RNO-9013148|reactome:R-RNO-9013408|ensembl:ENSRNOG00000020773(gene)|ensembl:ENSRNOT00000028185(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007254"(JNK cascade)|go:"GO:0007256"(obsolete activation of JNKK activity)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008219"(cell death)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0042802"(identical protein binding)|mint:MINT-8360019(identity) - comment:mint - figure legend:f5|comment:mint|full coverage: taxid:10116(rat-cerebral_cortica)|taxid:10116(Rattus norvegicus) - 2012/03/23 2014/10/16 rogid:0Eh9oL6GX10ePstSVMv0PpRnFWQ10116 rogid:1jm43Y+10bdj8htAiNA4XVc8nhQ10116 intact-crc:12FC637230C0FE69|rigid:yemI3/MwfQz9Mr3nBLJewfqSg5w false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P42260 uniprotkb:Q66HA1 intact:EBI-7809795|ensembl:ENSRNOP00000068172|intact:MINT-8359884 intact:EBI-4279420|uniprotkb:Q80YF1|ensembl:ENSRNOP00000028185 psi-mi:grik2_rat(display_long)|uniprotkb:Grik2(gene name)|psi-mi:Grik2(display_short)|uniprotkb:Glur6(gene name synonym)|uniprotkb:Glutamate receptor 6(gene name synonym) psi-mi:m3k11_rat(display_long)|uniprotkb:Map3k11(gene name)|psi-mi:Map3k11(display_short)|uniprotkb:Mlk3(gene name synonym)|uniprotkb:Mixed lineage kinase 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhu et al. (2012) pubmed:22483987|mint:MINT-8359886 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7809919|mint:MINT-8359986 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000000368(gene)|ensembl:ENSRNOT00000076234(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005234"(extracellularly glutamate-gated ion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015277"(kainate selective glutamate receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032983"(kainate selective glutamate receptor complex)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0043204"(perikaryon)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051967"(negative regulation of synaptic transmission, glutamatergic)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:0120169"(detection of cold stimulus involved in thermoception)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:1S50|rcsb pdb:1S7Y|rcsb pdb:1S9T|rcsb pdb:1SD3|rcsb pdb:1TT1|rcsb pdb:1YAE|rcsb pdb:2I0B|rcsb pdb:2I0C|rcsb pdb:2XXR|rcsb pdb:2XXT|rcsb pdb:2XXU|rcsb pdb:2XXV|rcsb pdb:2XXW|rcsb pdb:2XXX|rcsb pdb:2XXY|rcsb pdb:3G3F|rcsb pdb:3G3G|rcsb pdb:3G3H|rcsb pdb:3G3I|rcsb pdb:3G3J|rcsb pdb:3G3K|rcsb pdb:3H6G|rcsb pdb:3H6H|rcsb pdb:3QLT|rcsb pdb:3QLU|rcsb pdb:3QLV|rcsb pdb:4BDL|rcsb pdb:4BDM|rcsb pdb:4BDN|rcsb pdb:4BDO|rcsb pdb:4BDQ|rcsb pdb:4BDR|rcsb pdb:4H8I|rcsb pdb:4UQQ|rcsb pdb:5CMK|rcsb pdb:5CMM|rcsb pdb:5KUF|rcsb pdb:5KUH|rcsb pdb:7KS0|rcsb pdb:7KS3|reactome:R-RNO-451307|reactome:R-RNO-451308|refseq:NP_062182.1|rgd:2733|dip:DIP-29256N|mint:MINT-8359988(identity)|uniprotkb:P42260(original identifier) rgd:1359261|refseq:NP_001013168.1|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044843"(cell cycle G1/S phase transition)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016231(Mitogen-activated protein kinase kinase kinase, 9/10/11)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035779|interpro:IPR036028|reactome:R-RNO-5673000|reactome:R-RNO-9013148|reactome:R-RNO-9013408|ensembl:ENSRNOG00000020773(gene)|ensembl:ENSRNOT00000028185(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007254"(JNK cascade)|go:"GO:0007256"(obsolete activation of JNKK activity)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008219"(cell death)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0042802"(identical protein binding)|mint:MINT-8360023(identity) - comment:mint - figure legend:f3a|comment:mint|full coverage: taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2012/03/23 2014/10/16 rogid:0Eh9oL6GX10ePstSVMv0PpRnFWQ10116 rogid:1jm43Y+10bdj8htAiNA4XVc8nhQ10116 intact-crc:982F600C5DF4F4D1|rigid:yemI3/MwfQz9Mr3nBLJewfqSg5w false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P42260 uniprotkb:Q16584 intact:EBI-7809795|ensembl:ENSRNOP00000068172|intact:MINT-8359884 intact:EBI-49961|uniprotkb:Q53H00|uniprotkb:Q59F06|uniprotkb:Q6P2G4|uniprotkb:B4DS76|ensembl:ENSP00000309597 psi-mi:grik2_rat(display_long)|uniprotkb:Grik2(gene name)|psi-mi:Grik2(display_short)|uniprotkb:Glur6(gene name synonym)|uniprotkb:Glutamate receptor 6(gene name synonym) psi-mi:m3k11_human(display_long)|uniprotkb:MAP3K11(gene name)|psi-mi:MAP3K11(display_short)|uniprotkb:Mixed lineage kinase 3(gene name synonym)|uniprotkb:Src-homology 3 domain-containing proline-rich kinase(gene name synonym)|uniprotkb:SPRK(gene name synonym)|uniprotkb:PTK1(gene name synonym)|uniprotkb:MLK3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Zhu et al. (2012) pubmed:22483987|mint:MINT-8359886 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7810035|mint:MINT-8360001 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000000368(gene)|ensembl:ENSRNOT00000076234(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005234"(extracellularly glutamate-gated ion channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015277"(kainate selective glutamate receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032983"(kainate selective glutamate receptor complex)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0043204"(perikaryon)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051967"(negative regulation of synaptic transmission, glutamatergic)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060080"(inhibitory postsynaptic potential)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:0120169"(detection of cold stimulus involved in thermoception)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:1S50|rcsb pdb:1S7Y|rcsb pdb:1S9T|rcsb pdb:1SD3|rcsb pdb:1TT1|rcsb pdb:1YAE|rcsb pdb:2I0B|rcsb pdb:2I0C|rcsb pdb:2XXR|rcsb pdb:2XXT|rcsb pdb:2XXU|rcsb pdb:2XXV|rcsb pdb:2XXW|rcsb pdb:2XXX|rcsb pdb:2XXY|rcsb pdb:3G3F|rcsb pdb:3G3G|rcsb pdb:3G3H|rcsb pdb:3G3I|rcsb pdb:3G3J|rcsb pdb:3G3K|rcsb pdb:3H6G|rcsb pdb:3H6H|rcsb pdb:3QLT|rcsb pdb:3QLU|rcsb pdb:3QLV|rcsb pdb:4BDL|rcsb pdb:4BDM|rcsb pdb:4BDN|rcsb pdb:4BDO|rcsb pdb:4BDQ|rcsb pdb:4BDR|rcsb pdb:4H8I|rcsb pdb:4UQQ|rcsb pdb:5CMK|rcsb pdb:5CMM|rcsb pdb:5KUF|rcsb pdb:5KUH|rcsb pdb:7KS0|rcsb pdb:7KS3|reactome:R-RNO-451307|reactome:R-RNO-451308|refseq:NP_062182.1|rgd:2733|dip:DIP-29256N|mint:MINT-8360003(identity)|uniprotkb:P42260(original identifier) refseq:NP_002410.1|ensembl:ENSG00000173327(gene)|ensembl:ENST00000309100(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007254"(JNK cascade)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008219"(cell death)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044843"(cell cycle G1/S phase transition)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016231(Mitogen-activated protein kinase kinase kinase, 9/10/11)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035779|interpro:IPR036028|mint:Q16584|rcsb pdb:5K26|rcsb pdb:5K28|rcsb pdb:6AQB|rcsb pdb:6CQ7|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802955|reactome:R-HSA-9013148|reactome:R-HSA-9013408|reactome:R-HSA-9649948|mint:MINT-8360027(identity) - comment:mint - comment:mint|figure legend:f3b f3c|full coverage: taxid:9606(human-sh_sy5y)|taxid:9606(Homo sapiens SH-SY5Y cell line) - 2012/03/23 2014/10/16 rogid:0Eh9oL6GX10ePstSVMv0PpRnFWQ10116 rogid:njuMQIbuVFlWXNggegg3zYAKmS49606 intact-crc:9067F03EC35D40E0|rigid:Y7T4hiTjq6jP8Tftu0y/cRl2KtA false mutation decreasing interaction:886-886(MINT-8360015) - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P58502 uniprotkb:P58502 intact:EBI-7810114|ensemblbacteria:BAD85864|uniprotkb:Q977F5|intact:MINT-8404006 intact:EBI-7810114|ensemblbacteria:BAD85864|uniprotkb:Q977F5|intact:MINT-8404006 psi-mi:tksu_theko(display_long)|uniprotkb:TK1675(locus name) psi-mi:tksu_theko(display_long)|uniprotkb:TK1675(locus name) psi-mi:"MI:0114"(x-ray crystallography) Zhu et al. (2012) pubmed:22483987|mint:MINT-8359886 taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)") taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7810109|mint:MINT-8404014 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3WIU|rcsb pdb:3WIV|ensemblbacteria:BAD85864(transcript)|ensemblbacteria:TK1675(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0042802"(identical protein binding)|interpro:IPR034202|rcsb pdb:3A3O|rcsb pdb:2Z2X|rcsb pdb:3VHQ|rcsb pdb:2Z2Z|rcsb pdb:3A3P|rcsb pdb:2Z56|interpro:IPR015500(Peptidase S8, subtilisin-related)|rcsb pdb:2Z57|rcsb pdb:3VV2|rcsb pdb:2ZWP|interpro:IPR023828|rcsb pdb:2Z58|rcsb pdb:2ZRQ|rcsb pdb:2Z30|rcsb pdb:2E1P|interpro:IPR023827|rcsb pdb:2ZWO|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|rcsb pdb:2Z2Y|rcsb pdb:3A3N|refseq:WP_011250626.1|interpro:IPR036852|interpro:IPR037045|rcsb pdb:4JP8|mint:MINT-8404018(identity)|uniprotkb:P58502(original identifier) rcsb pdb:3WIU|rcsb pdb:3WIV|ensemblbacteria:BAD85864(transcript)|ensemblbacteria:TK1675(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0042802"(identical protein binding)|interpro:IPR034202|rcsb pdb:3A3O|rcsb pdb:2Z2X|rcsb pdb:3VHQ|rcsb pdb:2Z2Z|rcsb pdb:3A3P|rcsb pdb:2Z56|interpro:IPR015500(Peptidase S8, subtilisin-related)|rcsb pdb:2Z57|rcsb pdb:3VV2|rcsb pdb:2ZWP|interpro:IPR023828|rcsb pdb:2Z58|rcsb pdb:2ZRQ|rcsb pdb:2Z30|rcsb pdb:2E1P|interpro:IPR023827|rcsb pdb:2ZWO|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|rcsb pdb:2Z2Y|rcsb pdb:3A3N|refseq:WP_011250626.1|interpro:IPR036852|interpro:IPR037045|rcsb pdb:4JP8|mint:MINT-8404015(identity)|uniprotkb:P58502(original identifier) - comment:mint comment:mint figure legend:T1 F5|comment:mint|full coverage: taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/03/23 2014/10/16 rogid:y6B5p9oFnBH6n58UGsc64jASqvk69014 rogid:y6B5p9oFnBH6n58UGsc64jASqvk69014 intact-crc:46C566C0EEE18B4F|rigid:dHO22h/E+/qEcHxciMRu04Dcn+Q false binding-associated region:1-69(MINT-8404067) binding-associated region:70-398(MINT-8404070) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58502 uniprotkb:P58502 intact:EBI-7810114|ensemblbacteria:BAD85864|uniprotkb:Q977F5|intact:MINT-8404006 intact:EBI-7810114|ensemblbacteria:BAD85864|uniprotkb:Q977F5|intact:MINT-8404006 psi-mi:tksu_theko(display_long)|uniprotkb:TK1675(locus name) psi-mi:tksu_theko(display_long)|uniprotkb:TK1675(locus name) psi-mi:"MI:0107"(surface plasmon resonance) Zhu et al. (2012) pubmed:22483987|mint:MINT-8359886 taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)") taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7810170|mint:MINT-8404025 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3WIU|rcsb pdb:3WIV|ensemblbacteria:BAD85864(transcript)|ensemblbacteria:TK1675(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0042802"(identical protein binding)|interpro:IPR034202|rcsb pdb:3A3O|rcsb pdb:2Z2X|rcsb pdb:3VHQ|rcsb pdb:2Z2Z|rcsb pdb:3A3P|rcsb pdb:2Z56|interpro:IPR015500(Peptidase S8, subtilisin-related)|rcsb pdb:2Z57|rcsb pdb:3VV2|rcsb pdb:2ZWP|interpro:IPR023828|rcsb pdb:2Z58|rcsb pdb:2ZRQ|rcsb pdb:2Z30|rcsb pdb:2E1P|interpro:IPR023827|rcsb pdb:2ZWO|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|rcsb pdb:2Z2Y|rcsb pdb:3A3N|refseq:WP_011250626.1|interpro:IPR036852|interpro:IPR037045|rcsb pdb:4JP8|mint:MINT-8404029(identity)|uniprotkb:P58502(original identifier) rcsb pdb:3WIU|rcsb pdb:3WIV|ensemblbacteria:BAD85864(transcript)|ensemblbacteria:TK1675(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0042802"(identical protein binding)|interpro:IPR034202|rcsb pdb:3A3O|rcsb pdb:2Z2X|rcsb pdb:3VHQ|rcsb pdb:2Z2Z|rcsb pdb:3A3P|rcsb pdb:2Z56|interpro:IPR015500(Peptidase S8, subtilisin-related)|rcsb pdb:2Z57|rcsb pdb:3VV2|rcsb pdb:2ZWP|interpro:IPR023828|rcsb pdb:2Z58|rcsb pdb:2ZRQ|rcsb pdb:2Z30|rcsb pdb:2E1P|interpro:IPR023827|rcsb pdb:2ZWO|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|rcsb pdb:2Z2Y|rcsb pdb:3A3N|refseq:WP_011250626.1|interpro:IPR036852|interpro:IPR037045|rcsb pdb:4JP8|mint:MINT-8404026(identity)|uniprotkb:P58502(original identifier) - comment:mint comment:mint figure legend:SF3|comment:mint|full coverage: taxid:-1(in vitro)|taxid:-1(In vitro) kd:5.2x10^-11(molar) 2012/03/23 2014/10/16 rogid:y6B5p9oFnBH6n58UGsc64jASqvk69014 rogid:y6B5p9oFnBH6n58UGsc64jASqvk69014 intact-crc:3EC71A56CDD7EA64|rigid:dHO22h/E+/qEcHxciMRu04Dcn+Q false binding-associated region:1-69(MINT-8404061) binding-associated region:70-398(MINT-8404064) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P58502 - intact:EBI-7810114|ensemblbacteria:BAD85864|uniprotkb:Q977F5|intact:MINT-8404006 - psi-mi:tksu_theko(display_long)|uniprotkb:TK1675(locus name) - psi-mi:"MI:0415"(enzymatic study) Zhu et al. (2012) pubmed:22483987|mint:MINT-8359886 taxid:69014(theko)|taxid:69014("Thermococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)") - psi-mi:"MI:0194"(cleavage reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7810199|mint:MINT-8404046 - - psi-mi:"MI:0503"(self) - psi-mi:"MI:0503"(self) - psi-mi:"MI:0326"(protein) - rcsb pdb:3WIU|rcsb pdb:3WIV|ensemblbacteria:BAD85864(transcript)|ensemblbacteria:TK1675(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0042802"(identical protein binding)|interpro:IPR034202|rcsb pdb:3A3O|rcsb pdb:2Z2X|rcsb pdb:3VHQ|rcsb pdb:2Z2Z|rcsb pdb:3A3P|rcsb pdb:2Z56|interpro:IPR015500(Peptidase S8, subtilisin-related)|rcsb pdb:2Z57|rcsb pdb:3VV2|rcsb pdb:2ZWP|interpro:IPR023828|rcsb pdb:2Z58|rcsb pdb:2ZRQ|rcsb pdb:2Z30|rcsb pdb:2E1P|interpro:IPR023827|rcsb pdb:2ZWO|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|rcsb pdb:2Z2Y|rcsb pdb:3A3N|refseq:WP_011250626.1|interpro:IPR036852|interpro:IPR037045|rcsb pdb:4JP8|mint:MINT-8404051(identity)|uniprotkb:P58502(original identifier) - - comment:mint - figure legend:f2|comment:mint|intra-molecular:true|full coverage: taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/03/23 2014/10/16 rogid:y6B5p9oFnBH6n58UGsc64jASqvk69014 - intact-crc:2DE4994FC6695833 false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) -