#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q96D31	uniprotkb:Q96BY9	intact:EBI-2291476|uniprotkb:Q3MHV3|uniprotkb:Q6DHX2|uniprotkb:Q96BP7|uniprotkb:Q96K71|ensembl:ENSP00000482568	intact:EBI-722561|uniprotkb:Q53HE8|uniprotkb:Q9UNZ3|uniprotkb:Q9Y683|uniprotkb:D3DSU7|uniprotkb:B3KQQ4|uniprotkb:B7Z9J1|uniprotkb:H9MHJ8|uniprotkb:H9MHJ9|ensembl:ENSP00000256255	psi-mi:crcm1_human(display_long)|uniprotkb:ORAI1(gene name)|psi-mi:ORAI1(display_short)|uniprotkb:CRACM1(gene name synonym)|uniprotkb:TMEM142A(gene name synonym)|uniprotkb:Protein orai-1(gene name synonym)|uniprotkb:Transmembrane protein 142A(gene name synonym)	psi-mi:saraf_human(display_long)|uniprotkb:SARAF(gene name)|psi-mi:SARAF(display_short)|uniprotkb:HBV X-transactivated gene 3 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 3(gene name synonym)|uniprotkb:Protein FOAP-7(gene name synonym)|uniprotkb:TMEM66(gene name synonym)|uniprotkb:Transmembrane protein 66(gene name synonym)|uniprotkb:XTP3(gene name synonym)|uniprotkb:HSPC035(orf name)|uniprotkb:NPD003(orf name)|uniprotkb:PSEC0019(orf name)|uniprotkb:UNQ1967/PRO4499(orf name)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Palty et al. (2012)	pubmed:22464749|imex:IM-17326	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6127663|imex:IM-17326-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116179.2|go:"GO:0070588"(calcium ion transmembrane transport)|interpro:IPR012446(Protein of unknown function DUF1650)|interpro:IPR038350|rcsb pdb:2MAK|rcsb pdb:4EHQ|reactome:R-HSA-139853|reactome:R-HSA-5578775|reactome:R-HSA-983695|ensembl:ENSG00000276045(gene)|ensembl:ENST00000617316(transcript)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045121"(membrane raft)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0061180"(mammary gland epithelium development)|go:"GO:0070509"(calcium ion import)|dip:DIP-46289N	refseq:NP_001271168.1|refseq:NP_057211.4|ensembl:ENSG00000133872(gene)|ensembl:ENST00000256255(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006816"(calcium ion transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR009567(Protein of unknown function DUF1183)|rcsb pdb:6O2U|rcsb pdb:6O2V|rcsb pdb:6O2W	go:"GO:0005783"(endoplasmic reticulum)	-	-	figure legend:Fig. 4C, 5D, Supp. Fig. 6|comment:results indicate that SARAF and STIM1 associate under resting conditions and that store operated calcium entry activation promotes molecular rearrangements between STIM1 and SARAF C termini in an Orai1-dependent manner.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/05/15	2014/10/16	rogid:VXcTrF/8sZA01XGUFZwvu75L7Kw9606	rogid:qxgObw0slMLCKeF+2YAHTxjlkQk9606	intact-crc:DFD17BA77223440C|rigid:xZP00QV/C/gFW05vItMZdExte/4	false	-	yellow fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q96D31	uniprotkb:Q13586	intact:EBI-2291476|uniprotkb:Q3MHV3|uniprotkb:Q6DHX2|uniprotkb:Q96BP7|uniprotkb:Q96K71|ensembl:ENSP00000482568	intact:EBI-448878|uniprotkb:Q8N382|ensembl:ENSP00000300737|uniprotkb:E9PQJ4	psi-mi:crcm1_human(display_long)|uniprotkb:ORAI1(gene name)|psi-mi:ORAI1(display_short)|uniprotkb:CRACM1(gene name synonym)|uniprotkb:TMEM142A(gene name synonym)|uniprotkb:Protein orai-1(gene name synonym)|uniprotkb:Transmembrane protein 142A(gene name synonym)	psi-mi:stim1_human(display_long)|uniprotkb:STIM1(gene name)|psi-mi:STIM1(display_short)|uniprotkb:GOK(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Palty et al. (2012)	pubmed:22464749|imex:IM-17326	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6127663|imex:IM-17326-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116179.2|go:"GO:0070588"(calcium ion transmembrane transport)|interpro:IPR012446(Protein of unknown function DUF1650)|interpro:IPR038350|rcsb pdb:2MAK|rcsb pdb:4EHQ|reactome:R-HSA-139853|reactome:R-HSA-5578775|reactome:R-HSA-983695|ensembl:ENSG00000276045(gene)|ensembl:ENST00000617316(transcript)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045121"(membrane raft)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0061180"(mammary gland epithelium development)|go:"GO:0070509"(calcium ion import)|dip:DIP-46289N	refseq:NP_003147.2|ensembl:ENSG00000167323(gene)|ensembl:ENST00000300737(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070166"(enamel mineralization)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR030463|interpro:IPR032393|interpro:IPR037608|interpro:IPR037609|rcsb pdb:2K60|rcsb pdb:2MAJ|rcsb pdb:2MAK|rcsb pdb:3TEQ|rcsb pdb:4O9B|rcsb pdb:6YEL|reactome:R-HSA-139853|reactome:R-HSA-5578775|reactome:R-HSA-983695|refseq:NP_001264891.1|dip:DIP-31121N	go:"GO:0005783"(endoplasmic reticulum)	-	-	figure legend:Fig. 4C, 5D, Supp. Fig. 6|comment:results indicate that SARAF and STIM1 associate under resting conditions and that store operated calcium entry activation promotes molecular rearrangements between STIM1 and SARAF C termini in an Orai1-dependent manner.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/05/15	2014/10/16	rogid:VXcTrF/8sZA01XGUFZwvu75L7Kw9606	rogid:GQh8kgCwqrcx7VtJdv63pW1eg/U9606	intact-crc:DFD17BA77223440C|rigid:xZP00QV/C/gFW05vItMZdExte/4	false	-	sufficient binding region:196-339|mcherry fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q96BY9	uniprotkb:Q13586	intact:EBI-722561|uniprotkb:Q53HE8|uniprotkb:Q9UNZ3|uniprotkb:Q9Y683|uniprotkb:D3DSU7|uniprotkb:B3KQQ4|uniprotkb:B7Z9J1|uniprotkb:H9MHJ8|uniprotkb:H9MHJ9|ensembl:ENSP00000256255	intact:EBI-448878|uniprotkb:Q8N382|ensembl:ENSP00000300737|uniprotkb:E9PQJ4	psi-mi:saraf_human(display_long)|uniprotkb:SARAF(gene name)|psi-mi:SARAF(display_short)|uniprotkb:HBV X-transactivated gene 3 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 3(gene name synonym)|uniprotkb:Protein FOAP-7(gene name synonym)|uniprotkb:TMEM66(gene name synonym)|uniprotkb:Transmembrane protein 66(gene name synonym)|uniprotkb:XTP3(gene name synonym)|uniprotkb:HSPC035(orf name)|uniprotkb:NPD003(orf name)|uniprotkb:PSEC0019(orf name)|uniprotkb:UNQ1967/PRO4499(orf name)	psi-mi:stim1_human(display_long)|uniprotkb:STIM1(gene name)|psi-mi:STIM1(display_short)|uniprotkb:GOK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Palty et al. (2012)	pubmed:22464749|imex:IM-17326	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6127641|imex:IM-17326-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271168.1|refseq:NP_057211.4|ensembl:ENSG00000133872(gene)|ensembl:ENST00000256255(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006816"(calcium ion transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR009567(Protein of unknown function DUF1183)|rcsb pdb:6O2U|rcsb pdb:6O2V|rcsb pdb:6O2W	refseq:NP_003147.2|ensembl:ENSG00000167323(gene)|ensembl:ENST00000300737(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070166"(enamel mineralization)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR030463|interpro:IPR032393|interpro:IPR037608|interpro:IPR037609|rcsb pdb:2K60|rcsb pdb:2MAJ|rcsb pdb:2MAK|rcsb pdb:3TEQ|rcsb pdb:4O9B|rcsb pdb:6YEL|reactome:R-HSA-139853|reactome:R-HSA-5578775|reactome:R-HSA-983695|refseq:NP_001264891.1|dip:DIP-31121N	go:"GO:0005783"(endoplasmic reticulum)	-	-	figure legend:Fig. 5C, 5D|comment:Traces of Orai1 immunopercipitate were also detected, which the authors attributed to its native interaction with STIM1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/05/15	2014/10/16	rogid:qxgObw0slMLCKeF+2YAHTxjlkQk9606	rogid:GQh8kgCwqrcx7VtJdv63pW1eg/U9606	intact-crc:E5A982511E142A6A|rigid:CSVt+o/SjlIyuQsXhNmMUrrA6As	false	yellow fluorescent protein tag:?-?|sufficient binding region:196-339	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96BY9	uniprotkb:Q96D31	intact:EBI-722561|uniprotkb:Q53HE8|uniprotkb:Q9UNZ3|uniprotkb:Q9Y683|uniprotkb:D3DSU7|uniprotkb:B3KQQ4|uniprotkb:B7Z9J1|uniprotkb:H9MHJ8|uniprotkb:H9MHJ9|ensembl:ENSP00000256255	intact:EBI-2291476|uniprotkb:Q3MHV3|uniprotkb:Q6DHX2|uniprotkb:Q96BP7|uniprotkb:Q96K71|ensembl:ENSP00000482568	psi-mi:saraf_human(display_long)|uniprotkb:SARAF(gene name)|psi-mi:SARAF(display_short)|uniprotkb:HBV X-transactivated gene 3 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 3(gene name synonym)|uniprotkb:Protein FOAP-7(gene name synonym)|uniprotkb:TMEM66(gene name synonym)|uniprotkb:Transmembrane protein 66(gene name synonym)|uniprotkb:XTP3(gene name synonym)|uniprotkb:HSPC035(orf name)|uniprotkb:NPD003(orf name)|uniprotkb:PSEC0019(orf name)|uniprotkb:UNQ1967/PRO4499(orf name)	psi-mi:crcm1_human(display_long)|uniprotkb:ORAI1(gene name)|psi-mi:ORAI1(display_short)|uniprotkb:CRACM1(gene name synonym)|uniprotkb:TMEM142A(gene name synonym)|uniprotkb:Protein orai-1(gene name synonym)|uniprotkb:Transmembrane protein 142A(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Palty et al. (2012)	pubmed:22464749|imex:IM-17326	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6127551|imex:IM-17326-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271168.1|refseq:NP_057211.4|ensembl:ENSG00000133872(gene)|ensembl:ENST00000256255(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006816"(calcium ion transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR009567(Protein of unknown function DUF1183)|rcsb pdb:6O2U|rcsb pdb:6O2V|rcsb pdb:6O2W	refseq:NP_116179.2|go:"GO:0070588"(calcium ion transmembrane transport)|interpro:IPR012446(Protein of unknown function DUF1650)|interpro:IPR038350|rcsb pdb:2MAK|rcsb pdb:4EHQ|reactome:R-HSA-139853|reactome:R-HSA-5578775|reactome:R-HSA-983695|ensembl:ENSG00000276045(gene)|ensembl:ENST00000617316(transcript)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045121"(membrane raft)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0061180"(mammary gland epithelium development)|go:"GO:0070509"(calcium ion import)|dip:DIP-46289N	go:"GO:0005783"(endoplasmic reticulum)	-	-	figure legend:Fig. 3C, 3D, Supp. Fig. 4D|comment:Silencing STIM1 and STIM2 protein levels inhibited the Tg-induced SARAF-GFP translocation in the presence of Orai1-mCherry|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/05/15	2014/10/16	rogid:qxgObw0slMLCKeF+2YAHTxjlkQk9606	rogid:VXcTrF/8sZA01XGUFZwvu75L7Kw9606	intact-crc:E441356FA73162BA|rigid:Aa2gxZDIPDthf9gXOKTJP1lXbjs	false	sufficient binding region:196-339|yellow fluorescent protein tag:?-?	mcherry fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q96BY9	uniprotkb:Q13586	intact:EBI-722561|uniprotkb:Q53HE8|uniprotkb:Q9UNZ3|uniprotkb:Q9Y683|uniprotkb:D3DSU7|uniprotkb:B3KQQ4|uniprotkb:B7Z9J1|uniprotkb:H9MHJ8|uniprotkb:H9MHJ9|ensembl:ENSP00000256255	intact:EBI-448878|uniprotkb:Q8N382|ensembl:ENSP00000300737|uniprotkb:E9PQJ4	psi-mi:saraf_human(display_long)|uniprotkb:SARAF(gene name)|psi-mi:SARAF(display_short)|uniprotkb:HBV X-transactivated gene 3 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 3(gene name synonym)|uniprotkb:Protein FOAP-7(gene name synonym)|uniprotkb:TMEM66(gene name synonym)|uniprotkb:Transmembrane protein 66(gene name synonym)|uniprotkb:XTP3(gene name synonym)|uniprotkb:HSPC035(orf name)|uniprotkb:NPD003(orf name)|uniprotkb:PSEC0019(orf name)|uniprotkb:UNQ1967/PRO4499(orf name)	psi-mi:stim1_human(display_long)|uniprotkb:STIM1(gene name)|psi-mi:STIM1(display_short)|uniprotkb:GOK(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Palty et al. (2012)	pubmed:22464749|imex:IM-17326	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6127541|imex:IM-17326-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001271168.1|refseq:NP_057211.4|ensembl:ENSG00000133872(gene)|ensembl:ENST00000256255(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006816"(calcium ion transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR009567(Protein of unknown function DUF1183)|rcsb pdb:6O2U|rcsb pdb:6O2V|rcsb pdb:6O2W	refseq:NP_003147.2|ensembl:ENSG00000167323(gene)|ensembl:ENST00000300737(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070166"(enamel mineralization)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR030463|interpro:IPR032393|interpro:IPR037608|interpro:IPR037609|rcsb pdb:2K60|rcsb pdb:2MAJ|rcsb pdb:2MAK|rcsb pdb:3TEQ|rcsb pdb:4O9B|rcsb pdb:6YEL|reactome:R-HSA-139853|reactome:R-HSA-5578775|reactome:R-HSA-983695|refseq:NP_001264891.1|dip:DIP-31121N	go:"GO:0005783"(endoplasmic reticulum)	-	-	figure legend:Fig. 1G, 3B, Supp Fig. 5B and Movie S1|comment:"Addition of Thapsigargin (an irreversible sarcoplasmic/endoplasmic reticulum Ca2+-ATPase), induced translocation of the complex to the plasma membrane."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/05/15	2014/10/16	rogid:qxgObw0slMLCKeF+2YAHTxjlkQk9606	rogid:GQh8kgCwqrcx7VtJdv63pW1eg/U9606	intact-crc:71CA3054CFACDBF7|rigid:CSVt+o/SjlIyuQsXhNmMUrrA6As	false	yellow fluorescent protein tag:?-?	mcherry fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q96D31	uniprotkb:Q13586	intact:EBI-2291476|uniprotkb:Q3MHV3|uniprotkb:Q6DHX2|uniprotkb:Q96BP7|uniprotkb:Q96K71|ensembl:ENSP00000482568	intact:EBI-448878|uniprotkb:Q8N382|ensembl:ENSP00000300737|uniprotkb:E9PQJ4	psi-mi:crcm1_human(display_long)|uniprotkb:ORAI1(gene name)|psi-mi:ORAI1(display_short)|uniprotkb:CRACM1(gene name synonym)|uniprotkb:TMEM142A(gene name synonym)|uniprotkb:Protein orai-1(gene name synonym)|uniprotkb:Transmembrane protein 142A(gene name synonym)	psi-mi:stim1_human(display_long)|uniprotkb:STIM1(gene name)|psi-mi:STIM1(display_short)|uniprotkb:GOK(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Palty et al. (2012)	pubmed:22464749|imex:IM-17326	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6127767|imex:IM-17326-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_116179.2|go:"GO:0070588"(calcium ion transmembrane transport)|interpro:IPR012446(Protein of unknown function DUF1650)|interpro:IPR038350|rcsb pdb:2MAK|rcsb pdb:4EHQ|reactome:R-HSA-139853|reactome:R-HSA-5578775|reactome:R-HSA-983695|ensembl:ENSG00000276045(gene)|ensembl:ENST00000617316(transcript)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015279"(store-operated calcium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045121"(membrane raft)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0061180"(mammary gland epithelium development)|go:"GO:0070509"(calcium ion import)|dip:DIP-46289N	refseq:NP_003147.2|ensembl:ENSG00000167323(gene)|ensembl:ENST00000300737(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070166"(enamel mineralization)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR030463|interpro:IPR032393|interpro:IPR037608|interpro:IPR037609|rcsb pdb:2K60|rcsb pdb:2MAJ|rcsb pdb:2MAK|rcsb pdb:3TEQ|rcsb pdb:4O9B|rcsb pdb:6YEL|reactome:R-HSA-139853|reactome:R-HSA-5578775|reactome:R-HSA-983695|refseq:NP_001264891.1|dip:DIP-31121N	go:"GO:0005886"(plasma membrane)	-	-	agonist:"Thapsigargin (an irreversible sarcoplasmic/endoplasmic reticulum Ca2+-ATPase)"|figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/05/15	2014/10/16	rogid:VXcTrF/8sZA01XGUFZwvu75L7Kw9606	rogid:GQh8kgCwqrcx7VtJdv63pW1eg/U9606	intact-crc:ED764A564D22C5B3|rigid:vcTi++PINtFYRSz2u8Diz54La3s	false	mcherry fluorescent protein tag:?-?	yellow fluorescent protein tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)