#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8TAK6 uniprotkb:O95273 intact:EBI-3867416|uniprotkb:Q7RTS0|ensembl:ENSP00000371785 intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213 psi-mi:olig1_human(display_long)|uniprotkb:OLIG1(gene name)|psi-mi:OLIG1(display_short)|uniprotkb:BHLHB6(gene name synonym)|uniprotkb:BHLHE21(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 6(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 21(gene name synonym) psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ishii et al. (2012) doi:10.1038/emboj.2012.77|pubmed:22453338|imex:IM-18513|mint:MINT-8395578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7803050|mint:MINT-8396226|imex:IM-18513-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620450.2|ensembl:ENSG00000184221(gene)|ensembl:ENST00000382348(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048663"(neuron fate commitment)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR032657|interpro:IPR036638|mint:Q8TAK6|mint:MINT-8396229(identity) refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|mint:MINT-8396228(identity) - - - comment:homomint|comment:mint|figure legend:f6 sf6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2012/10/02 2014/10/16 rogid:6zU+GDe1CfmWRzr5E6Bx5NzmLoY9606 rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606 intact-crc:29A5540025E4AC32|rigid:3YpkiQHaQG4ecPasoSJW+hhu8L0 false myc tag:?-?(MINT-8396252) flag tag:?-?(MINT-8396256) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O95273 uniprotkb:P24385 intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213 intact:EBI-375001|uniprotkb:Q6LEF0|ensembl:ENSP00000227507 psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym) psi-mi:ccnd1_human(display_long)|uniprotkb:CCND1(gene name)|psi-mi:CCND1(display_short)|uniprotkb:BCL1(gene name synonym)|uniprotkb:PRAD1(gene name synonym)|uniprotkb:PRAD1 oncogene(gene name synonym)|uniprotkb:BCL-1 oncogene(gene name synonym)|uniprotkb:B-cell lymphoma 1 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ishii et al. (2012) doi:10.1038/emboj.2012.77|pubmed:22453338|imex:IM-18513|mint:MINT-8395578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7803086|mint:MINT-8396267|imex:IM-18513-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|mint:MINT-8396269(identity) refseq:NP_444284.1|ensembl:ENSG00000110092(gene)|ensembl:ENST00000227507(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000320"(re-entry into mitotic cell cycle)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010039"(response to iron ion)|go:"GO:0010165"(response to X-ray)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032355"(response to estradiol)|go:"GO:0033197"(response to vitamin E)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0042493"|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043627"(response to estrogen)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070141"(response to UV-A)|go:"GO:0097421"(liver regeneration)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR015451(Cyclin D)|interpro:IPR036915|interpro:IPR039361|mint:P24385|rcsb pdb:2W96|rcsb pdb:2W99|rcsb pdb:2W9F|rcsb pdb:2W9Z|rcsb pdb:5VZU|rcsb pdb:6P8E|rcsb pdb:6P8F|rcsb pdb:6P8G|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-1912408|reactome:R-HSA-3214858|reactome:R-HSA-6785807|reactome:R-HSA-69231|reactome:R-HSA-75815|reactome:R-HSA-8849470|reactome:R-HSA-8853884|reactome:R-HSA-8878166|reactome:R-HSA-8934593|reactome:R-HSA-8951430|reactome:R-HSA-8951936|go:"GO:0044321"(response to leptin)|reactome:R-HSA-9018519|reactome:R-HSA-9634638|reactome:R-HSA-9661069|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0051301"(cell division)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051726"(regulation of cell cycle)|dip:DIP-123N|mint:MINT-8396273(identity) - - - comment:homomint|comment:mint|figure legend:f6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2012/10/02 2014/10/16 rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606 rogid:XIMa4dI7+QiodOusigAjalaEIJk9606 intact-crc:0BF83F3731D3B67B|rigid:zLUHhxRjsgxMZ5oAImR0UlTpO+g false flag tag:?-?(MINT-8396270) myc tag:?-?(MINT-8396274) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O95273 uniprotkb:Q02363 intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213 intact:EBI-713450|ensembl:ENSP00000234091|ensembl:ENSP00000379585|ensembl:ENSP00000385465 psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym) psi-mi:id2_human(display_long)|uniprotkb:Inhibitor of DNA binding 2(gene name synonym)|uniprotkb:ID2(gene name)|psi-mi:ID2(display_short)|uniprotkb:BHLHB26(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 26(gene name synonym)|uniprotkb:Inhibitor of differentiation 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ishii et al. (2012) doi:10.1038/emboj.2012.77|pubmed:22453338|imex:IM-18513|mint:MINT-8395578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7803104|mint:MINT-8396281|imex:IM-18513-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|mint:MINT-8396283(identity) ensembl:ENSG00000115738(gene)|ensembl:ENST00000234091(transcript)|ensembl:ENST00000331129(transcript)|ensembl:ENST00000396290(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0003166"(bundle of His development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030154"(cell differentiation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045578"(negative regulation of B cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051148"(negative regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0061030"(epithelial cell differentiation involved in mammary gland alveolus development)|go:"GO:0061031"(endodermal digestive tract morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0090398"(cellular senescence)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|mint:Q02363|rcsb pdb:4AYA|reactome:R-HSA-9031628|refseq:NP_002157.2|dip:DIP-46874N|mint:MINT-8396287(identity) - - - comment:homomint|comment:mint|figure legend:f6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2012/10/02 2014/10/16 rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606 rogid:zKX4mIq64fyS8DVPGQNeL7+c50w9606 intact-crc:FAA440265AE271F3|rigid:l1s3Q3UriOGq6/e/vEsJ0Q79KW8 false flag tag:?-?(MINT-8396284)|mutation increasing interaction:166-166(MINT-8396296) myc tag:?-?(MINT-8396288) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q60867 uniprotkb:O95273 intact:EBI-309315|uniprotkb:Q545N9|uniprotkb:Q60897|ensembl:ENSMUSP00000040364 intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213 psi-mi:ndf1_mouse(display_long)|uniprotkb:Neurod1(gene name)|psi-mi:Neurod1(display_short)|uniprotkb:Neurod(gene name synonym)|uniprotkb:Beta-cell E-box transcriptional activator 2(gene name synonym) psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ishii et al. (2012) doi:10.1038/emboj.2012.77|pubmed:22453338|imex:IM-18513|mint:MINT-8395578 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7803126|mint:MINT-8396300|imex:IM-18513-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035024.1|ensembl:ENSMUST00000041099(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003326"(pancreatic A cell fate commitment)|go:"GO:0003329"(pancreatic PP cell fate commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0009749"(response to glucose)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021549"(cerebellum development)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030073"(insulin secretion)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0035881"(amacrine cell differentiation)|go:"GO:0035883"(enteroendocrine cell differentiation)|ensembl:ENSMUSG00000034701(gene)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR016637(Transcription factor, basic helix-loop-helix, NeuroD)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR022575|interpro:IPR032652|go:"GO:0048562"(embryonic organ morphogenesis)|interpro:IPR036638|rcsb pdb:2QL2|go:"GO:0048666"(neuron development)|go:"GO:0048839"(inner ear development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060730"(regulation of intestinal epithelial structure maintenance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|mint:MINT-8396308(identity) refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|mint:MINT-8396302(identity) - - - comment:mint|figure legend:f6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2012/10/02 2014/10/16 rogid:EOCuRlE8Dhx0NzTQi52B/NrEt0A10090 rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606 intact-crc:5C2B6F53AE517A56|rigid:2pWC20OqczXo1//xD/Mr0IqvDi4 false myc tag:?-?(MINT-8396309) mutation increasing interaction:166-166(MINT-8396303)|flag tag:?-?(MINT-8396305) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O95273 uniprotkb:Q02363 intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213 intact:EBI-713450|ensembl:ENSP00000234091|ensembl:ENSP00000379585|ensembl:ENSP00000385465 psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym) psi-mi:id2_human(display_long)|uniprotkb:Inhibitor of DNA binding 2(gene name synonym)|uniprotkb:ID2(gene name)|psi-mi:ID2(display_short)|uniprotkb:BHLHB26(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 26(gene name synonym)|uniprotkb:Inhibitor of differentiation 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ishii et al. (2012) doi:10.1038/emboj.2012.77|pubmed:22453338|imex:IM-18513|mint:MINT-8395578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7803147|mint:MINT-8396313|imex:IM-18513-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|mint:MINT-8396315(identity) ensembl:ENSG00000115738(gene)|ensembl:ENST00000234091(transcript)|ensembl:ENST00000331129(transcript)|ensembl:ENST00000396290(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0003166"(bundle of His development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030154"(cell differentiation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045578"(negative regulation of B cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051148"(negative regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0061030"(epithelial cell differentiation involved in mammary gland alveolus development)|go:"GO:0061031"(endodermal digestive tract morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0090398"(cellular senescence)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|mint:Q02363|rcsb pdb:4AYA|reactome:R-HSA-9031628|refseq:NP_002157.2|dip:DIP-46874N|mint:MINT-8396321(identity) - - - comment:homomint|comment:mint|figure legend:f6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2012/10/02 2014/10/16 rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606 rogid:zKX4mIq64fyS8DVPGQNeL7+c50w9606 intact-crc:938090DDC8128AD3|rigid:l1s3Q3UriOGq6/e/vEsJ0Q79KW8 false flag tag:?-?(MINT-8396316)|mutation increasing interaction:169-169(MINT-8396318) myc tag:?-?(MINT-8396322) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q60867 uniprotkb:O95273 intact:EBI-309315|uniprotkb:Q545N9|uniprotkb:Q60897|ensembl:ENSMUSP00000040364 intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213 psi-mi:ndf1_mouse(display_long)|uniprotkb:Neurod1(gene name)|psi-mi:Neurod1(display_short)|uniprotkb:Neurod(gene name synonym)|uniprotkb:Beta-cell E-box transcriptional activator 2(gene name synonym) psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ishii et al. (2012) doi:10.1038/emboj.2012.77|pubmed:22453338|imex:IM-18513|mint:MINT-8395578 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7803209|mint:MINT-8396343|imex:IM-18513-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035024.1|ensembl:ENSMUST00000041099(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003326"(pancreatic A cell fate commitment)|go:"GO:0003329"(pancreatic PP cell fate commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0009749"(response to glucose)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021549"(cerebellum development)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030073"(insulin secretion)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0035881"(amacrine cell differentiation)|go:"GO:0035883"(enteroendocrine cell differentiation)|ensembl:ENSMUSG00000034701(gene)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR016637(Transcription factor, basic helix-loop-helix, NeuroD)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR022575|interpro:IPR032652|go:"GO:0048562"(embryonic organ morphogenesis)|interpro:IPR036638|rcsb pdb:2QL2|go:"GO:0048666"(neuron development)|go:"GO:0048839"(inner ear development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060730"(regulation of intestinal epithelial structure maintenance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|mint:MINT-8396351(identity) refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|mint:MINT-8396345(identity) - - - comment:mint|figure legend:f6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2012/10/02 2014/10/16 rogid:EOCuRlE8Dhx0NzTQi52B/NrEt0A10090 rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606 intact-crc:4489C87EEA8E3ADF|rigid:2pWC20OqczXo1//xD/Mr0IqvDi4 false myc tag:?-?(MINT-8396352) flag tag:?-?(MINT-8396346)|mutation increasing interaction:271-271(MINT-8396348) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q02363 uniprotkb:O95273 intact:EBI-713450|ensembl:ENSP00000234091|ensembl:ENSP00000379585|ensembl:ENSP00000385465 intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213 psi-mi:id2_human(display_long)|uniprotkb:Inhibitor of DNA binding 2(gene name synonym)|uniprotkb:ID2(gene name)|psi-mi:ID2(display_short)|uniprotkb:BHLHB26(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 26(gene name synonym)|uniprotkb:Inhibitor of differentiation 2(gene name synonym) psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ishii et al. (2012) doi:10.1038/emboj.2012.77|pubmed:22453338|imex:IM-18513|mint:MINT-8395578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7803169|mint:MINT-8396328|imex:IM-18513-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000115738(gene)|ensembl:ENST00000234091(transcript)|ensembl:ENST00000331129(transcript)|ensembl:ENST00000396290(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0003166"(bundle of His development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030154"(cell differentiation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045578"(negative regulation of B cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051148"(negative regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0061030"(epithelial cell differentiation involved in mammary gland alveolus development)|go:"GO:0061031"(endodermal digestive tract morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0090398"(cellular senescence)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|mint:Q02363|rcsb pdb:4AYA|reactome:R-HSA-9031628|refseq:NP_002157.2|dip:DIP-46874N|mint:MINT-8396336(identity) refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|mint:MINT-8396330(identity) - - - comment:homomint|comment:mint|figure legend:f6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2012/10/02 2014/10/16 rogid:zKX4mIq64fyS8DVPGQNeL7+c50w9606 rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606 intact-crc:BFA06D8206899158|rigid:l1s3Q3UriOGq6/e/vEsJ0Q79KW8 false myc tag:?-?(MINT-8396337) flag tag:?-?(MINT-8396333)|mutation increasing interaction:271-271(MINT-8396331) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O95273 uniprotkb:Q60867 intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213 intact:EBI-309315|uniprotkb:Q545N9|uniprotkb:Q60897|ensembl:ENSMUSP00000040364 psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym) psi-mi:ndf1_mouse(display_long)|uniprotkb:Neurod1(gene name)|psi-mi:Neurod1(display_short)|uniprotkb:Neurod(gene name synonym)|uniprotkb:Beta-cell E-box transcriptional activator 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ishii et al. (2012) doi:10.1038/emboj.2012.77|pubmed:22453338|imex:IM-18513|mint:MINT-8395578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7803252|mint:MINT-8396371|imex:IM-18513-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|mint:MINT-8396373(identity) refseq:NP_035024.1|ensembl:ENSMUST00000041099(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003326"(pancreatic A cell fate commitment)|go:"GO:0003329"(pancreatic PP cell fate commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0009749"(response to glucose)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021549"(cerebellum development)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030073"(insulin secretion)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0035881"(amacrine cell differentiation)|go:"GO:0035883"(enteroendocrine cell differentiation)|ensembl:ENSMUSG00000034701(gene)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR016637(Transcription factor, basic helix-loop-helix, NeuroD)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR022575|interpro:IPR032652|go:"GO:0048562"(embryonic organ morphogenesis)|interpro:IPR036638|rcsb pdb:2QL2|go:"GO:0048666"(neuron development)|go:"GO:0048839"(inner ear development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060730"(regulation of intestinal epithelial structure maintenance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|mint:MINT-8396379(identity) - - - comment:mint|figure legend:f6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2012/10/02 2014/10/16 rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606 rogid:EOCuRlE8Dhx0NzTQi52B/NrEt0A10090 intact-crc:128DAEAA835E3556|rigid:2pWC20OqczXo1//xD/Mr0IqvDi4 false mutation increasing interaction:278-278(MINT-8396376)|flag tag:?-?(MINT-8396374) myc tag:?-?(MINT-8396380) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q60867 uniprotkb:O95273 intact:EBI-309315|uniprotkb:Q545N9|uniprotkb:Q60897|ensembl:ENSMUSP00000040364 intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213 psi-mi:ndf1_mouse(display_long)|uniprotkb:Neurod1(gene name)|psi-mi:Neurod1(display_short)|uniprotkb:Neurod(gene name synonym)|uniprotkb:Beta-cell E-box transcriptional activator 2(gene name synonym) psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ishii et al. (2012) doi:10.1038/emboj.2012.77|pubmed:22453338|imex:IM-18513|mint:MINT-8395578 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7803273|mint:MINT-8396384|imex:IM-18513-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035024.1|ensembl:ENSMUST00000041099(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003326"(pancreatic A cell fate commitment)|go:"GO:0003329"(pancreatic PP cell fate commitment)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0009749"(response to glucose)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021549"(cerebellum development)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030073"(insulin secretion)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030902"(hindbrain development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0035881"(amacrine cell differentiation)|go:"GO:0035883"(enteroendocrine cell differentiation)|ensembl:ENSMUSG00000034701(gene)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043010"(camera-type eye development)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR016637(Transcription factor, basic helix-loop-helix, NeuroD)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR022575|interpro:IPR032652|go:"GO:0048562"(embryonic organ morphogenesis)|interpro:IPR036638|rcsb pdb:2QL2|go:"GO:0048666"(neuron development)|go:"GO:0048839"(inner ear development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060730"(regulation of intestinal epithelial structure maintenance)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|mint:MINT-8396392(identity) refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|mint:MINT-8396386(identity) - - - comment:mint|figure legend:f6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2012/10/02 2014/10/16 rogid:EOCuRlE8Dhx0NzTQi52B/NrEt0A10090 rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606 intact-crc:639A906481D7AA02|rigid:2pWC20OqczXo1//xD/Mr0IqvDi4 false myc tag:?-?(MINT-8396393) mutation increasing interaction:169-169(MINT-8396387)|flag tag:?-?(MINT-8396389) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O95273 uniprotkb:Q02363 intact:EBI-748961|uniprotkb:A8K3Q0|uniprotkb:A8K3U2|uniprotkb:Q6ZQN9|uniprotkb:Q7Z519|uniprotkb:Q8NBS7|uniprotkb:Q8NBY2|uniprotkb:Q9NS19|uniprotkb:Q9NYH3|uniprotkb:Q9UHX9|ensembl:ENSP00000300213 intact:EBI-713450|ensembl:ENSP00000234091|ensembl:ENSP00000379585|ensembl:ENSP00000385465 psi-mi:ccdb1_human(display_long)|uniprotkb:Grap2 and cyclin-D-interacting protein(gene name synonym)|uniprotkb:Human homolog of Maid(gene name synonym)|uniprotkb:CCNDBP1(gene name)|psi-mi:CCNDBP1(display_short)|uniprotkb:DIP1(gene name synonym)|uniprotkb:GCIP(gene name synonym)|uniprotkb:HHM(gene name synonym) psi-mi:id2_human(display_long)|uniprotkb:Inhibitor of DNA binding 2(gene name synonym)|uniprotkb:ID2(gene name)|psi-mi:ID2(display_short)|uniprotkb:BHLHB26(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 26(gene name synonym)|uniprotkb:Inhibitor of differentiation 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ishii et al. (2012) doi:10.1038/emboj.2012.77|pubmed:22453338|imex:IM-18513|mint:MINT-8395578 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7803230|mint:MINT-8396356|imex:IM-18513-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036274.3|ensembl:ENSG00000166946(gene)|ensembl:ENST00000300213(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR026907|mint:O95273|rcsb pdb:3AY5|mint:MINT-8396358(identity) ensembl:ENSG00000115738(gene)|ensembl:ENST00000234091(transcript)|ensembl:ENST00000331129(transcript)|ensembl:ENST00000396290(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0003166"(bundle of His development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030154"(cell differentiation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045578"(negative regulation of B cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051148"(negative regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0061030"(epithelial cell differentiation involved in mammary gland alveolus development)|go:"GO:0061031"(endodermal digestive tract morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0090398"(cellular senescence)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR026052|interpro:IPR036638|mint:Q02363|rcsb pdb:4AYA|reactome:R-HSA-9031628|refseq:NP_002157.2|dip:DIP-46874N|mint:MINT-8396364(identity) - - - comment:homomint|comment:mint|figure legend:f6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2012/10/02 2014/10/16 rogid:Vi9aoFc+Mov6P3X6KGmsTxXqxvM9606 rogid:zKX4mIq64fyS8DVPGQNeL7+c50w9606 intact-crc:9C9337B7CAB3A46D|rigid:l1s3Q3UriOGq6/e/vEsJ0Q79KW8 false flag tag:?-?(MINT-8396361)|mutation increasing interaction:278-278(MINT-8396359) myc tag:?-?(MINT-8396365) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)