#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O94329 uniprotkb:O74113 intact:EBI-7790536|ensemblfungi:"SPBC725.13c.1:pep"|intact:MINT-4683278 intact:EBI-1559427|ensemblfungi:"SPAC17D4.02.1:pep" psi-mi:psf2_schpo(display_long)|uniprotkb:psf2(gene name)|psi-mi:psf2(display_short)|uniprotkb:bsh3(gene name synonym)|uniprotkb:dre13(gene name synonym)|uniprotkb:SPBC725.13c(orf name) psi-mi:cdc45_schpo(display_long)|uniprotkb:Suppressor of nda4 protein(gene name synonym)|uniprotkb:sna41(gene name)|psi-mi:sna41(display_short)|uniprotkb:SPAC17D4.02(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kanke et al. (2012) doi:10.1038/emboj.2012.68|pubmed:22433840|imex:IM-17567|mint:MINT-8380931 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7790530|mint:MINT-8380939|imex:IM-17567-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:SPBC725.13c(gene)|ensemblfungi:SPBC725.13c.1(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043596"(nuclear replication fork)|go:"GO:1902969"(mitotic DNA replication)|go:"GO:1902975"(mitotic DNA replication initiation)|refseq:NP_595493.1|interpro:IPR021151|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR036224|reactome:R-SPO-176974|mint:MINT-8380941(identity) interpro:IPR003874(CDC45-like protein)|refseq:NP_594693.1|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPAC17D4.02(gene)|ensemblfungi:SPAC17D4.02.1(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0043596"(nuclear replication fork)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|mint:MINT-8380943(identity) - comment:mint|function:The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation and is required for bir1 localization - comment:mint|figure legend:f3a sf5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") - 2012/05/28 2014/10/16 rogid:j8vJihTC1YyazBtj3vyFQm24wkc284812 rogid:44anfKY0HcHn6TKRaDvlh8tPUAU284812 intact-crc:3534AE7B7CC4B7F6|rigid:tcry/YqKUhqGivB3b9BzifVnAJk false flag tag:?-?(MINT-8380945) myc tag:?-?(MINT-8380955) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O94329 uniprotkb:P49731 intact:EBI-7790536|ensemblfungi:"SPBC725.13c.1:pep"|intact:MINT-4683278 intact:EBI-913838|uniprotkb:Q9P7R7|ensemblfungi:"SPBC211.04c.1:pep" psi-mi:psf2_schpo(display_long)|uniprotkb:psf2(gene name)|psi-mi:psf2(display_short)|uniprotkb:bsh3(gene name synonym)|uniprotkb:dre13(gene name synonym)|uniprotkb:SPBC725.13c(orf name) psi-mi:mcm6_schpo(display_long)|uniprotkb:mcm6(gene name)|psi-mi:mcm6(display_short)|uniprotkb:mis5(gene name synonym)|uniprotkb:SPBC211.04c(orf name)|uniprotkb:Minichromosome maintenance protein 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kanke et al. (2012) doi:10.1038/emboj.2012.68|pubmed:22433840|imex:IM-17567|mint:MINT-8380931 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7790530|mint:MINT-8380939|imex:IM-17567-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:SPBC725.13c(gene)|ensemblfungi:SPBC725.13c.1(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043596"(nuclear replication fork)|go:"GO:1902969"(mitotic DNA replication)|go:"GO:1902975"(mitotic DNA replication initiation)|refseq:NP_595493.1|interpro:IPR021151|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR036224|reactome:R-SPO-176974|mint:MINT-8380941(identity) interpro:IPR027925|ensemblfungi:SPBC211.04c(gene)|ensemblfungi:SPBC211.04c.1(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005829"(cytosol)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|go:"GO:1902975"(mitotic DNA replication initiation)|reactome:R-SPO-68949|refseq:NP_596614.1|interpro:IPR008049(MCM protein 6)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|reactome:R-SPO-68962|interpro:IPR027417|reactome:R-SPO-69052|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|reactome:R-SPO-68867|reactome:R-SPO-176187|mint:MINT-8380942(identity) - comment:mint|function:The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation and is required for bir1 localization - comment:mint|figure legend:f3a sf5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") - 2012/05/28 2014/10/16 rogid:j8vJihTC1YyazBtj3vyFQm24wkc284812 rogid:xySiHOX6v3x7mxe4TxjWl6vOHLA284812 intact-crc:3534AE7B7CC4B7F6|rigid:tcry/YqKUhqGivB3b9BzifVnAJk false flag tag:?-?(MINT-8380945) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O94329 uniprotkb:O74113 intact:EBI-7790536|ensemblfungi:"SPBC725.13c.1:pep"|intact:MINT-4683278 intact:EBI-1559427|ensemblfungi:"SPAC17D4.02.1:pep" psi-mi:psf2_schpo(display_long)|uniprotkb:psf2(gene name)|psi-mi:psf2(display_short)|uniprotkb:bsh3(gene name synonym)|uniprotkb:dre13(gene name synonym)|uniprotkb:SPBC725.13c(orf name) psi-mi:cdc45_schpo(display_long)|uniprotkb:Suppressor of nda4 protein(gene name synonym)|uniprotkb:sna41(gene name)|psi-mi:sna41(display_short)|uniprotkb:SPAC17D4.02(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kanke et al. (2012) doi:10.1038/emboj.2012.68|pubmed:22433840|imex:IM-17567|mint:MINT-8380931 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7790571|mint:MINT-8380958|imex:IM-17567-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:SPBC725.13c(gene)|ensemblfungi:SPBC725.13c.1(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043596"(nuclear replication fork)|go:"GO:1902969"(mitotic DNA replication)|go:"GO:1902975"(mitotic DNA replication initiation)|refseq:NP_595493.1|interpro:IPR021151|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR036224|reactome:R-SPO-176974|mint:MINT-8380960(identity) interpro:IPR003874(CDC45-like protein)|refseq:NP_594693.1|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPAC17D4.02(gene)|ensemblfungi:SPAC17D4.02.1(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0043596"(nuclear replication fork)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|mint:MINT-8380966(identity) - comment:mint|function:The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation and is required for bir1 localization - figure legend:f3b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") - 2012/05/28 2014/10/16 rogid:j8vJihTC1YyazBtj3vyFQm24wkc284812 rogid:44anfKY0HcHn6TKRaDvlh8tPUAU284812 intact-crc:418A6C4034A66A31|rigid:tRFLcpUG35vFlNcVvQDBfkv2/RQ false flag tag:?-?(MINT-8380961) myc tag:?-?(MINT-8380967) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O94329 uniprotkb:P49731 intact:EBI-7790536|ensemblfungi:"SPBC725.13c.1:pep"|intact:MINT-4683278 intact:EBI-913838|uniprotkb:Q9P7R7|ensemblfungi:"SPBC211.04c.1:pep" psi-mi:psf2_schpo(display_long)|uniprotkb:psf2(gene name)|psi-mi:psf2(display_short)|uniprotkb:bsh3(gene name synonym)|uniprotkb:dre13(gene name synonym)|uniprotkb:SPBC725.13c(orf name) psi-mi:mcm6_schpo(display_long)|uniprotkb:mcm6(gene name)|psi-mi:mcm6(display_short)|uniprotkb:mis5(gene name synonym)|uniprotkb:SPBC211.04c(orf name)|uniprotkb:Minichromosome maintenance protein 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kanke et al. (2012) doi:10.1038/emboj.2012.68|pubmed:22433840|imex:IM-17567|mint:MINT-8380931 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7790571|mint:MINT-8380958|imex:IM-17567-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:SPBC725.13c(gene)|ensemblfungi:SPBC725.13c.1(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043596"(nuclear replication fork)|go:"GO:1902969"(mitotic DNA replication)|go:"GO:1902975"(mitotic DNA replication initiation)|refseq:NP_595493.1|interpro:IPR021151|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR036224|reactome:R-SPO-176974|mint:MINT-8380960(identity) interpro:IPR027925|ensemblfungi:SPBC211.04c(gene)|ensemblfungi:SPBC211.04c.1(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005829"(cytosol)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|go:"GO:1902975"(mitotic DNA replication initiation)|reactome:R-SPO-68949|refseq:NP_596614.1|interpro:IPR008049(MCM protein 6)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|reactome:R-SPO-68962|interpro:IPR027417|reactome:R-SPO-69052|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|reactome:R-SPO-68867|reactome:R-SPO-176187|mint:MINT-8380964(identity) - comment:mint|function:The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation and is required for bir1 localization - figure legend:f3b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") - 2012/05/28 2014/10/16 rogid:j8vJihTC1YyazBtj3vyFQm24wkc284812 rogid:xySiHOX6v3x7mxe4TxjWl6vOHLA284812 intact-crc:418A6C4034A66A31|rigid:tRFLcpUG35vFlNcVvQDBfkv2/RQ false flag tag:?-?(MINT-8380961) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O94329 uniprotkb:P29458 intact:EBI-7790536|ensemblfungi:"SPBC725.13c.1:pep"|intact:MINT-4683278 intact:EBI-913806|uniprotkb:Q9P7K4|uniprotkb:Q9USM0 psi-mi:psf2_schpo(display_long)|uniprotkb:psf2(gene name)|psi-mi:psf2(display_short)|uniprotkb:bsh3(gene name synonym)|uniprotkb:dre13(gene name synonym)|uniprotkb:SPBC725.13c(orf name) psi-mi:mcm4_schpo(display_long)|uniprotkb:mcm4(gene name)|psi-mi:mcm4(display_short)|uniprotkb:cdc21(gene name synonym)|uniprotkb:SPCC16A11.17(orf name)|uniprotkb:SPCC24B10.01(orf name)|uniprotkb:Minichromosome maintenance protein 4(gene name synonym)|uniprotkb:Cell division control protein 21(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kanke et al. (2012) doi:10.1038/emboj.2012.68|pubmed:22433840|imex:IM-17567|mint:MINT-8380931 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7790571|mint:MINT-8380958|imex:IM-17567-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:SPBC725.13c(gene)|ensemblfungi:SPBC725.13c.1(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043596"(nuclear replication fork)|go:"GO:1902969"(mitotic DNA replication)|go:"GO:1902975"(mitotic DNA replication initiation)|refseq:NP_595493.1|interpro:IPR021151|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR036224|reactome:R-SPO-176974|mint:MINT-8380960(identity) interpro:IPR027925|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0030875"(rDNA protrusion)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|reactome:R-SPO-68949|interpro:IPR008047(MCM protein 4)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|reactome:R-SPO-69052|refseq:NP_588004.2|interpro:IPR031327|reactome:R-SPO-68962|interpro:IPR027417|interpro:IPR033762|interpro:IPR041562|reactome:R-SPO-68867|reactome:R-SPO-176187|mint:MINT-8380973(identity) - comment:mint|function:The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation and is required for bir1 localization - figure legend:f3b|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") - 2012/05/28 2014/10/16 rogid:j8vJihTC1YyazBtj3vyFQm24wkc284812 rogid:CIJriUICsfTJTJ0gT08sjo5nYjc284812 intact-crc:418A6C4034A66A31|rigid:tRFLcpUG35vFlNcVvQDBfkv2/RQ false flag tag:?-?(MINT-8380961) - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O42709 uniprotkb:P40377 intact:EBI-1387246|ensemblfungi:"SPBC1347.10.1:pep" intact:EBI-783248|ensemblfungi:"SPBC4.04c.1:pep" psi-mi:mcm10_schpo(display_long)|uniprotkb:mcm10(gene name)|psi-mi:mcm10(display_short)|uniprotkb:cdc23(gene name synonym)|uniprotkb:SPBC1347.10(orf name)|uniprotkb:Minichromosome maintenance protein 10(gene name synonym)|uniprotkb:Cdc23 protein(gene name synonym) psi-mi:mcm2_schpo(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:Cell division control protein 19(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short)|uniprotkb:cdc19(gene name synonym)|uniprotkb:nda1(gene name synonym)|uniprotkb:SPBC4.04c(orf name) psi-mi:"MI:0018"(two hybrid) Kanke et al. (2012) doi:10.1038/emboj.2012.68|pubmed:22433840|imex:IM-17567|mint:MINT-8380931 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7790638|mint:MINT-8381005|imex:IM-17567-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040184|refseq:NP_596702.1|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC1347.10(gene)|ensemblfungi:SPBC1347.10.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1903934"(positive regulation of DNA primase activity)|go:"GO:1904931"(MCM complex binding)|mint:MINT-8381011(identity) interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_595477.1|interpro:IPR008045(MCM protein 2)|reactome:R-SPO-176187|interpro:IPR031327|reactome:R-SPO-68962|reactome:R-SPO-69052|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|interpro:IPR041562|reactome:R-SPO-68867|ensemblfungi:SPBC4.04c(gene)|ensemblfungi:SPBC4.04c.1(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|reactome:R-SPO-68949|mint:MINT-8381007(identity) - - - comment:mint|figure legend:ST1 f7b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2012/05/28 2014/10/16 rogid:Wgb0hLMXCcdWiIMDh5hICrKQ5P0284812 rogid:b9w/1QXwh2OswMQSi6nQDuxooNg284812 intact-crc:C71A33061468343E|rigid:0LTv7m1v4NXhViaiOydntd0ui8c false fusion protein:?-?(MINT-8381012) fusion protein:?-?(MINT-8381008) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O42709 uniprotkb:P49731 intact:EBI-1387246|ensemblfungi:"SPBC1347.10.1:pep" intact:EBI-913838|uniprotkb:Q9P7R7|ensemblfungi:"SPBC211.04c.1:pep" psi-mi:mcm10_schpo(display_long)|uniprotkb:mcm10(gene name)|psi-mi:mcm10(display_short)|uniprotkb:cdc23(gene name synonym)|uniprotkb:SPBC1347.10(orf name)|uniprotkb:Minichromosome maintenance protein 10(gene name synonym)|uniprotkb:Cdc23 protein(gene name synonym) psi-mi:mcm6_schpo(display_long)|uniprotkb:mcm6(gene name)|psi-mi:mcm6(display_short)|uniprotkb:mis5(gene name synonym)|uniprotkb:SPBC211.04c(orf name)|uniprotkb:Minichromosome maintenance protein 6(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kanke et al. (2012) doi:10.1038/emboj.2012.68|pubmed:22433840|imex:IM-17567|mint:MINT-8380931 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7790621|mint:MINT-8380982|imex:IM-17567-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040184|refseq:NP_596702.1|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC1347.10(gene)|ensemblfungi:SPBC1347.10.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1903934"(positive regulation of DNA primase activity)|go:"GO:1904931"(MCM complex binding)|mint:MINT-8380984(identity) interpro:IPR027925|ensemblfungi:SPBC211.04c(gene)|ensemblfungi:SPBC211.04c.1(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005829"(cytosol)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|go:"GO:1902975"(mitotic DNA replication initiation)|reactome:R-SPO-68949|refseq:NP_596614.1|interpro:IPR008049(MCM protein 6)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|reactome:R-SPO-68962|interpro:IPR027417|reactome:R-SPO-69052|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|reactome:R-SPO-68867|reactome:R-SPO-176187|mint:MINT-8380988(identity) - - - comment:mint|figure legend:ST1 f7b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2012/05/28 2014/10/16 rogid:Wgb0hLMXCcdWiIMDh5hICrKQ5P0284812 rogid:xySiHOX6v3x7mxe4TxjWl6vOHLA284812 intact-crc:D8DB657F085A3B14|rigid:VdAIYnqg7bx7D8ztfqqrRjr/viw false fusion protein:?-?(MINT-8380985) fusion protein:?-?(MINT-8381000) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O42709 uniprotkb:P29458 intact:EBI-1387246|ensemblfungi:"SPBC1347.10.1:pep" intact:EBI-913806|uniprotkb:Q9P7K4|uniprotkb:Q9USM0 psi-mi:mcm10_schpo(display_long)|uniprotkb:mcm10(gene name)|psi-mi:mcm10(display_short)|uniprotkb:cdc23(gene name synonym)|uniprotkb:SPBC1347.10(orf name)|uniprotkb:Minichromosome maintenance protein 10(gene name synonym)|uniprotkb:Cdc23 protein(gene name synonym) psi-mi:mcm4_schpo(display_long)|uniprotkb:mcm4(gene name)|psi-mi:mcm4(display_short)|uniprotkb:cdc21(gene name synonym)|uniprotkb:SPCC16A11.17(orf name)|uniprotkb:SPCC24B10.01(orf name)|uniprotkb:Minichromosome maintenance protein 4(gene name synonym)|uniprotkb:Cell division control protein 21(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kanke et al. (2012) doi:10.1038/emboj.2012.68|pubmed:22433840|imex:IM-17567|mint:MINT-8380931 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7790655|mint:MINT-8381017|imex:IM-17567-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040184|refseq:NP_596702.1|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC1347.10(gene)|ensemblfungi:SPBC1347.10.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1903934"(positive regulation of DNA primase activity)|go:"GO:1904931"(MCM complex binding)|mint:MINT-8381019(identity) interpro:IPR027925|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0030875"(rDNA protrusion)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|reactome:R-SPO-68949|interpro:IPR008047(MCM protein 4)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|reactome:R-SPO-69052|refseq:NP_588004.2|interpro:IPR031327|reactome:R-SPO-68962|interpro:IPR027417|interpro:IPR033762|interpro:IPR041562|reactome:R-SPO-68867|reactome:R-SPO-176187|mint:MINT-8381023(identity) - - - comment:mint|figure legend:ST1 f7b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2012/05/28 2014/10/16 rogid:Wgb0hLMXCcdWiIMDh5hICrKQ5P0284812 rogid:CIJriUICsfTJTJ0gT08sjo5nYjc284812 intact-crc:8F5799F2123B0543|rigid:abj3dcVG+gwk9RFtdIoVKsq/etE false fusion protein:?-?(MINT-8381020) fusion protein:?-?(MINT-8381024) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O42709 uniprotkb:Q9P7C8 intact:EBI-1387246|ensemblfungi:"SPBC1347.10.1:pep" intact:EBI-7790689|ensemblfungi:"SPBP4H10.21c.1:pep"|intact:MINT-4705166 psi-mi:mcm10_schpo(display_long)|uniprotkb:mcm10(gene name)|psi-mi:mcm10(display_short)|uniprotkb:cdc23(gene name synonym)|uniprotkb:SPBC1347.10(orf name)|uniprotkb:Minichromosome maintenance protein 10(gene name synonym)|uniprotkb:Cdc23 protein(gene name synonym) psi-mi:sld5_schpo(display_long)|uniprotkb:sld5(gene name)|psi-mi:sld5(display_short)|uniprotkb:SPBP4H10.21c(orf name) psi-mi:"MI:0018"(two hybrid) Kanke et al. (2012) doi:10.1038/emboj.2012.68|pubmed:22433840|imex:IM-17567|mint:MINT-8380931 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7790705|mint:MINT-8381029|imex:IM-17567-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040184|refseq:NP_596702.1|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC1347.10(gene)|ensemblfungi:SPBC1347.10.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1903934"(positive regulation of DNA primase activity)|go:"GO:1904931"(MCM complex binding)|mint:MINT-8381031(identity) interpro:IPR031633|ensemblfungi:SPBP4H10.21c(gene)|ensemblfungi:SPBP4H10.21c.1(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR021151|refseq:NP_596195.1|interpro:IPR038749|interpro:IPR008591(GINS complex, Sld5 component)|interpro:IPR036224|reactome:R-SPO-176974|mint:MINT-8381035(identity) - - comment:mint|function:The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation and is required for bir1 localization comment:mint|figure legend:ST1 f7b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2012/05/28 2014/10/16 rogid:Wgb0hLMXCcdWiIMDh5hICrKQ5P0284812 rogid:tcJZZhSTZmlhIUdA1EYCscaG17U284812 intact-crc:6BC01CBBCB7A40B6|rigid:s3Stzabvcgi2JG1xEiUD+fB592w false fusion protein:?-?(MINT-8381032) fusion protein:?-?(MINT-8381036) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O42709 uniprotkb:Q9UTC3 intact:EBI-1387246|ensemblfungi:"SPBC1347.10.1:pep" intact:EBI-7790831|ensemblfungi:"SPAC227.16c.1:pep"|intact:MINT-4710100 psi-mi:mcm10_schpo(display_long)|uniprotkb:mcm10(gene name)|psi-mi:mcm10(display_short)|uniprotkb:cdc23(gene name synonym)|uniprotkb:SPBC1347.10(orf name)|uniprotkb:Minichromosome maintenance protein 10(gene name synonym)|uniprotkb:Cdc23 protein(gene name synonym) psi-mi:psf3_schpo(display_long)|uniprotkb:psf3(gene name)|psi-mi:psf3(display_short)|uniprotkb:SPAC227.16c(orf name) psi-mi:"MI:0018"(two hybrid) Kanke et al. (2012) doi:10.1038/emboj.2012.68|pubmed:22433840|imex:IM-17567|mint:MINT-8380931 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7790826|mint:MINT-8381065|imex:IM-17567-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040184|refseq:NP_596702.1|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC1347.10(gene)|ensemblfungi:SPBC1347.10.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1903934"(positive regulation of DNA primase activity)|go:"GO:1904931"(MCM complex binding)|mint:MINT-8381067(identity) ensemblfungi:SPAC227.16c(gene)|ensemblfungi:SPAC227.16c.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0043596"(nuclear replication fork)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR021151|refseq:NP_592970.1|interpro:IPR010492(GINS complex, Psf3 component)|interpro:IPR038437|interpro:IPR036224|reactome:R-SPO-176974|mint:MINT-8381071(identity) - - comment:mint|function:The GINS complex plays an essential role in the initiation of DNA replication comment:mint|figure legend:ST1 f7b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2012/05/28 2014/10/16 rogid:Wgb0hLMXCcdWiIMDh5hICrKQ5P0284812 rogid:VQ/YISe2ZFcL13MY8r5eae5OvZY284812 intact-crc:8FA4F1379C245393|rigid:jbcdLGGwZTEcxyAGrrcCBAQm/yc false fusion protein:?-?(MINT-8381068) fusion protein:?-?(MINT-8381072) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O42709 uniprotkb:Q9P7X6 intact:EBI-1387246|ensemblfungi:"SPBC1347.10.1:pep" intact:EBI-7790763|ensemblfungi:"SPBP23A10.09.1:pep"|intact:MINT-4706602 psi-mi:mcm10_schpo(display_long)|uniprotkb:mcm10(gene name)|psi-mi:mcm10(display_short)|uniprotkb:cdc23(gene name synonym)|uniprotkb:SPBC1347.10(orf name)|uniprotkb:Minichromosome maintenance protein 10(gene name synonym)|uniprotkb:Cdc23 protein(gene name synonym) psi-mi:psf1_schpo(display_long)|uniprotkb:psf1(gene name)|psi-mi:psf1(display_short)|uniprotkb:SPBP23A10.09(orf name) psi-mi:"MI:0018"(two hybrid) Kanke et al. (2012) doi:10.1038/emboj.2012.68|pubmed:22433840|imex:IM-17567|mint:MINT-8380931 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7790758|mint:MINT-8381041|imex:IM-17567-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040184|refseq:NP_596702.1|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC1347.10(gene)|ensemblfungi:SPBC1347.10.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1903934"(positive regulation of DNA primase activity)|go:"GO:1904931"(MCM complex binding)|mint:MINT-8381043(identity) ensemblfungi:SPBP23A10.09(gene)|ensemblfungi:SPBP23A10.09.1(transcript)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0043596"(nuclear replication fork)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1902983"(DNA strand elongation involved in mitotic DNA replication)|refseq:NP_595821.1|interpro:IPR021151|interpro:IPR005339(GINS complex, Psf1 component)|interpro:IPR036224|reactome:R-SPO-176974|mint:MINT-8381047(identity) - - comment:mint|function:The GINS complex plays an essential role in the initiation of DNA replication comment:mint|figure legend:ST1 f7b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2012/05/28 2014/10/16 rogid:Wgb0hLMXCcdWiIMDh5hICrKQ5P0284812 rogid:mG+K9biTwFXuDhLV/oBz/urWJgM284812 intact-crc:48A232A62D7BE478|rigid:Hk+SA5MZAQZiUYzlli22e9f0jKo false fusion protein:?-?(MINT-8381044) fusion protein:?-?(MINT-8381048) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O42709 uniprotkb:O94329 intact:EBI-1387246|ensemblfungi:"SPBC1347.10.1:pep" intact:EBI-7790536|ensemblfungi:"SPBC725.13c.1:pep"|intact:MINT-4683278 psi-mi:mcm10_schpo(display_long)|uniprotkb:mcm10(gene name)|psi-mi:mcm10(display_short)|uniprotkb:cdc23(gene name synonym)|uniprotkb:SPBC1347.10(orf name)|uniprotkb:Minichromosome maintenance protein 10(gene name synonym)|uniprotkb:Cdc23 protein(gene name synonym) psi-mi:psf2_schpo(display_long)|uniprotkb:psf2(gene name)|psi-mi:psf2(display_short)|uniprotkb:bsh3(gene name synonym)|uniprotkb:dre13(gene name synonym)|uniprotkb:SPBC725.13c(orf name) psi-mi:"MI:0018"(two hybrid) Kanke et al. (2012) doi:10.1038/emboj.2012.68|pubmed:22433840|imex:IM-17567|mint:MINT-8380931 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7790790|mint:MINT-8381053|imex:IM-17567-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040184|refseq:NP_596702.1|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC1347.10(gene)|ensemblfungi:SPBC1347.10.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1903934"(positive regulation of DNA primase activity)|go:"GO:1904931"(MCM complex binding)|mint:MINT-8381055(identity) ensemblfungi:SPBC725.13c(gene)|ensemblfungi:SPBC725.13c.1(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043596"(nuclear replication fork)|go:"GO:1902969"(mitotic DNA replication)|go:"GO:1902975"(mitotic DNA replication initiation)|refseq:NP_595493.1|interpro:IPR021151|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR036224|reactome:R-SPO-176974|mint:MINT-8381059(identity) - - comment:mint|function:The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation and is required for bir1 localization comment:mint|figure legend:ST1 f7b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2012/05/28 2014/10/16 rogid:Wgb0hLMXCcdWiIMDh5hICrKQ5P0284812 rogid:j8vJihTC1YyazBtj3vyFQm24wkc284812 intact-crc:FFF683DAF6873AEF|rigid:pw8Rx0GFf1CZ/PV7QCnVxrx5Yjw false fusion protein:?-?(MINT-8381056) fusion protein:?-?(MINT-8381060) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O42709 uniprotkb:O94263 intact:EBI-1387246|ensemblfungi:"SPBC1347.10.1:pep" intact:EBI-866632|ensemblfungi:"SPBP8B7.14c.1:pep" psi-mi:mcm10_schpo(display_long)|uniprotkb:mcm10(gene name)|psi-mi:mcm10(display_short)|uniprotkb:cdc23(gene name synonym)|uniprotkb:SPBC1347.10(orf name)|uniprotkb:Minichromosome maintenance protein 10(gene name synonym)|uniprotkb:Cdc23 protein(gene name synonym) psi-mi:dpb2_schpo(display_long)|uniprotkb:dpb2(gene name)|psi-mi:dpb2(display_short)|uniprotkb:SPBP8B7.14c(orf name)|uniprotkb:DNA polymerase II subunit 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kanke et al. (2012) doi:10.1038/emboj.2012.68|pubmed:22433840|imex:IM-17567|mint:MINT-8380931 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7790912|mint:MINT-8381089|imex:IM-17567-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040184|refseq:NP_596702.1|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC1347.10(gene)|ensemblfungi:SPBC1347.10.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1903934"(positive regulation of DNA primase activity)|go:"GO:1904931"(MCM complex binding)|mint:MINT-8381091(identity) interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|refseq:NP_596521.1|reactome:R-SPO-68952|reactome:R-SPO-68962|reactome:R-SPO-110314|reactome:R-SPO-5651801|reactome:R-SPO-5656169|reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|interpro:IPR016266(DNA polymerase epsilon, subunit B)|ensemblfungi:SPBP8B7.14c(gene)|ensemblfungi:SPBP8B7.14c.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0042276"(error-prone translesion synthesis)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0140529"(CMG complex assembly)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1902983"(DNA strand elongation involved in mitotic DNA replication)|mint:MINT-8381095(identity) - - - comment:mint|figure legend:ST1 f7b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2012/05/28 2014/10/16 rogid:Wgb0hLMXCcdWiIMDh5hICrKQ5P0284812 rogid:F8FVfd5pMNrHSuGL8MOoLVxwqqk284812 intact-crc:EC54FFD46BDF905F|rigid:bSho/ANnhA9HrxOAl4+XJgBNIAI false fusion protein:?-?(MINT-8381092) fusion protein:?-?(MINT-8381096) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O42709 uniprotkb:P87154 intact:EBI-1387246|ensemblfungi:"SPBC1347.10.1:pep" intact:EBI-876811|ensemblfungi:"SPBC25H2.13c.1:pep"|uniprotkb:P78873 psi-mi:mcm10_schpo(display_long)|uniprotkb:mcm10(gene name)|psi-mi:mcm10(display_short)|uniprotkb:cdc23(gene name synonym)|uniprotkb:SPBC1347.10(orf name)|uniprotkb:Minichromosome maintenance protein 10(gene name synonym)|uniprotkb:Cdc23 protein(gene name synonym) psi-mi:dpoe_schpo(display_long)|uniprotkb:pol2(gene name)|psi-mi:pol2(display_short)|uniprotkb:cdc20(gene name synonym)|uniprotkb:SPBC25H2.13c(orf name)|uniprotkb:DNA polymerase II subunit A(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kanke et al. (2012) doi:10.1038/emboj.2012.68|pubmed:22433840|imex:IM-17567|mint:MINT-8380931 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7790876|mint:MINT-8381077|imex:IM-17567-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040184|refseq:NP_596702.1|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC1347.10(gene)|ensemblfungi:SPBC1347.10.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1903934"(positive regulation of DNA primase activity)|go:"GO:1904931"(MCM complex binding)|mint:MINT-8381079(identity) ensemblfungi:SPBC25H2.13c(gene)|ensemblfungi:SPBC25H2.13c.1(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006297"(nucleotide-excision repair, DNA gap filling)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008310"(single-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008622"(epsilon DNA polymerase complex)|go:"GO:0031048"(heterochromatin assembly by small RNA)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0045004"(DNA replication proofreading)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061806"(regulation of DNA recombination at centromere)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:0140529"(CMG complex assembly)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1902983"(DNA strand elongation involved in mitotic DNA replication)|go:"GO:1903097"(regulation of CENP-A containing nucleosome assembly)|go:"GO:1903460"(mitotic DNA replication leading strand elongation)|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR013697(Region of unknown function DUF1744)|interpro:IPR029703|interpro:IPR036397|interpro:IPR042087|interpro:IPR043502|refseq:NP_596354.1|reactome:R-SPO-68952|reactome:R-SPO-68962|reactome:R-SPO-110314|reactome:R-SPO-5651801|reactome:R-SPO-5656169|reactome:R-SPO-5696397|reactome:R-SPO-5696400|reactome:R-SPO-6782135|reactome:R-SPO-6782210|dip:DIP-36490N|mint:MINT-8381083(identity) - - crc64:A80A5D0865EEBC3E comment:mint|figure legend:ST1 f7b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2012/05/28 2014/10/16 rogid:Wgb0hLMXCcdWiIMDh5hICrKQ5P0284812 rogid:YE7WnqMf/XahbkojRXIY4Y9hRks284812 intact-crc:472E2EA503606986|rigid:PV4cnGi6jD6UTY8ohwnoLLyWweM false fusion protein:?-?(MINT-8381080) fusion protein:?-?(MINT-8381084) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O42709 uniprotkb:P32372 intact:EBI-1387246|ensemblfungi:"SPBC1347.10.1:pep" intact:EBI-768521|ensemblfungi:"SPAC23C4.18c.1:pep" psi-mi:mcm10_schpo(display_long)|uniprotkb:mcm10(gene name)|psi-mi:mcm10(display_short)|uniprotkb:cdc23(gene name synonym)|uniprotkb:SPBC1347.10(orf name)|uniprotkb:Minichromosome maintenance protein 10(gene name synonym)|uniprotkb:Cdc23 protein(gene name synonym) psi-mi:rad4_schpo(display_long)|uniprotkb:Protein cut5(gene name synonym)|uniprotkb:P74(gene name synonym)|uniprotkb:rad4(gene name)|psi-mi:rad4(display_short)|uniprotkb:cut5(gene name synonym)|uniprotkb:SPAC23C4.18c(orf name) psi-mi:"MI:0018"(two hybrid) Kanke et al. (2012) doi:10.1038/emboj.2012.68|pubmed:22433840|imex:IM-17567|mint:MINT-8380931 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7790929|mint:MINT-8381101|imex:IM-17567-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040184|refseq:NP_596702.1|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC1347.10(gene)|ensemblfungi:SPBC1347.10.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1903934"(positive regulation of DNA primase activity)|go:"GO:1904931"(MCM complex binding)|mint:MINT-8381103(identity) rcsb pdb:4BMC|rcsb pdb:4BMD|rcsb pdb:4BU0|rcsb pdb:4BU1|refseq:NP_593190.1|interpro:IPR001357(BRCT)|interpro:IPR036420|rcsb pdb:6HM3|rcsb pdb:6HM4|ensemblfungi:SPAC23C4.18c(gene)|ensemblfungi:SPAC23C4.18c.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0072686"(mitotic spindle)|mint:MINT-8381107(identity) - - - comment:mint|figure legend:ST1 f7b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2012/05/28 2014/10/16 rogid:Wgb0hLMXCcdWiIMDh5hICrKQ5P0284812 rogid:6rgRCxmDXZyDmbaoeIIPhfJvu8g284812 intact-crc:E87F3184C2EF703D|rigid:YZvNemaCaXgKB9jpF1MzEiWqKDw false fusion protein:?-?(MINT-8381104) fusion protein:?-?(MINT-8381108) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O42709 uniprotkb:O14216 intact:EBI-1387246|ensemblfungi:"SPBC1347.10.1:pep" intact:EBI-7790946|ensemblfungi:"SPAC6B12.11.1:pep"|intact:MINT-4671463 psi-mi:mcm10_schpo(display_long)|uniprotkb:mcm10(gene name)|psi-mi:mcm10(display_short)|uniprotkb:cdc23(gene name synonym)|uniprotkb:SPBC1347.10(orf name)|uniprotkb:Minichromosome maintenance protein 10(gene name synonym)|uniprotkb:Cdc23 protein(gene name synonym) psi-mi:sld2_schpo(display_long)|uniprotkb:drc1(gene name)|psi-mi:drc1(display_short)|uniprotkb:sld2(gene name synonym)|uniprotkb:SPAC6B12.11(orf name)|uniprotkb:DNA replication and checkpoint protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kanke et al. (2012) doi:10.1038/emboj.2012.68|pubmed:22433840|imex:IM-17567|mint:MINT-8380931 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7790963|mint:MINT-8381113|imex:IM-17567-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040184|refseq:NP_596702.1|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC1347.10(gene)|ensemblfungi:SPBC1347.10.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1903934"(positive regulation of DNA primase activity)|go:"GO:1904931"(MCM complex binding)|mint:MINT-8381115(identity) ensemblfungi:SPAC6B12.11(gene)|ensemblfungi:SPAC6B12.11.1(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:1902969"(mitotic DNA replication)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|refseq:NP_593766.1|interpro:IPR021110|interpro:IPR040203|mint:MINT-8381119(identity) - - comment:mint|function:Has a role in the intiation of DNA replication. Required at S-phase checkpoint comment:mint|figure legend:ST1 f7b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2012/05/28 2014/10/16 rogid:Wgb0hLMXCcdWiIMDh5hICrKQ5P0284812 rogid:FoD6/RkHDimcC5e0JidK2CE63VI284812 intact-crc:935FEA10179C6A2F|rigid:x6mV5gL2KJrwlvxt0Wdik5FoFvM false fusion protein:?-?(MINT-8381116) fusion protein:?-?(MINT-8381120) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O42709 uniprotkb:O42709 intact:EBI-1387246|ensemblfungi:"SPBC1347.10.1:pep" intact:EBI-1387246|ensemblfungi:"SPBC1347.10.1:pep" psi-mi:mcm10_schpo(display_long)|uniprotkb:mcm10(gene name)|psi-mi:mcm10(display_short)|uniprotkb:cdc23(gene name synonym)|uniprotkb:SPBC1347.10(orf name)|uniprotkb:Minichromosome maintenance protein 10(gene name synonym)|uniprotkb:Cdc23 protein(gene name synonym) psi-mi:mcm10_schpo(display_long)|uniprotkb:mcm10(gene name)|psi-mi:mcm10(display_short)|uniprotkb:cdc23(gene name synonym)|uniprotkb:SPBC1347.10(orf name)|uniprotkb:Minichromosome maintenance protein 10(gene name synonym)|uniprotkb:Cdc23 protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Kanke et al. (2012) doi:10.1038/emboj.2012.68|pubmed:22433840|imex:IM-17567|mint:MINT-8380931 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7791005|mint:MINT-8381125|imex:IM-17567-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR040184|refseq:NP_596702.1|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC1347.10(gene)|ensemblfungi:SPBC1347.10.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1903934"(positive regulation of DNA primase activity)|go:"GO:1904931"(MCM complex binding)|mint:MINT-8381131(identity) interpro:IPR040184|refseq:NP_596702.1|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC1347.10(gene)|ensemblfungi:SPBC1347.10.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1903934"(positive regulation of DNA primase activity)|go:"GO:1904931"(MCM complex binding)|mint:MINT-8381127(identity) - - - comment:mint|figure legend:ST1 f7b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2012/05/28 2014/10/16 rogid:Wgb0hLMXCcdWiIMDh5hICrKQ5P0284812 rogid:Wgb0hLMXCcdWiIMDh5hICrKQ5P0284812 intact-crc:1D898D6839744168|rigid:KGsef9DBb2WEaHBHeumUUrSXDZw false fusion protein:?-?(MINT-8381132) fusion protein:?-?(MINT-8381128)|mutation decreasing interaction:321-321(MINT-8381139)|mutation decreasing interaction:324-324(MINT-8381142)|mutation decreasing interaction:309-309(MINT-8381136) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)