#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8TEX9 uniprotkb:Q8IWY9 intact:EBI-395967|uniprotkb:Q2NL96|uniprotkb:Q86TZ9|uniprotkb:Q8NCG8|uniprotkb:Q96SJ3|uniprotkb:Q9BTI4|uniprotkb:Q9H5L0|uniprotkb:B2RN95|ensembl:ENSP00000346453|ensembl:ENSP00000494795 intact:EBI-726307|uniprotkb:Q6NYD0|uniprotkb:Q7Z7L5|uniprotkb:Q969N3|ensembl:ENSP00000348564 psi-mi:ipo4_human(display_long)|uniprotkb:IPO4(gene name)|psi-mi:IPO4(display_short)|uniprotkb:IMP4B(gene name synonym)|uniprotkb:RANBP4(gene name synonym)|uniprotkb:Importin-4b(gene name synonym)|uniprotkb:Ran-binding protein 4(gene name synonym) psi-mi:cdan1_human(display_long)|uniprotkb:CDAN1(gene name)|psi-mi:CDAN1(display_short)|uniprotkb:UNQ664/PRO1295(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Ask et al. (2012) doi:10.1038/emboj.2012.55|pubmed:22407294|imex:IM-18773|mint:MINT-8388457 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7785351|mint:MINT-8388465|imex:IM-18773-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078934.3|dip:DIP-32944N|ensembl:ENSG00000196497(gene)|ensembl:ENSG00000285248(gene)|ensembl:ENST00000354464(transcript)|ensembl:ENST00000644546(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR034085|interpro:IPR040122|mint:Q8TEX9|rcsb pdb:5XAH|rcsb pdb:5XBK|mint:MINT-8388469(identity) refseq:NP_612486.2|dip:DIP-24225N|ensembl:ENSG00000140326(gene)|ensembl:ENST00000356231(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0008104"(protein localization)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031497"(chromatin assembly)|interpro:IPR028171|interpro:IPR040031|mint:Q8IWY9|mint:MINT-8388467(identity) - - - figure legend:f1d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line) - 2012/07/19 2014/10/16 rogid:PVIcGG3WTf0QmYbS0vvy049EjlQ9606 rogid:Hbm36aMIq0BwSxCOLnxRl3vyYZY9606 intact-crc:D1103B57CA56D669|rigid:fhCl/NuZUbV21f9UI8YhezTuNzQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IWY9 uniprotkb:Q9NVP2 intact:EBI-726307|uniprotkb:Q6NYD0|uniprotkb:Q7Z7L5|uniprotkb:Q969N3|ensembl:ENSP00000348564 intact:EBI-1055650|uniprotkb:Q53G51|uniprotkb:Q9NVZ0|ensembl:ENSP00000263382|ensembl:ENSP00000499863 psi-mi:cdan1_human(display_long)|uniprotkb:CDAN1(gene name)|psi-mi:CDAN1(display_short)|uniprotkb:UNQ664/PRO1295(orf name) psi-mi:asf1b_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog B(gene name synonym)|uniprotkb:CCG1-interacting factor A-II(gene name synonym)|uniprotkb:ASF1B(gene name)|psi-mi:ASF1B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ask et al. (2012) doi:10.1038/emboj.2012.55|pubmed:22407294|imex:IM-18773|mint:MINT-8388457 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7785406|mint:MINT-8408119|imex:IM-18773-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_612486.2|dip:DIP-24225N|ensembl:ENSG00000140326(gene)|ensembl:ENST00000356231(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0008104"(protein localization)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031497"(chromatin assembly)|interpro:IPR028171|interpro:IPR040031|mint:Q8IWY9|mint:MINT-8408123(identity) refseq:NP_060624.1|ensembl:ENSG00000105011(gene)|ensembl:ENSG00000288210(gene)|ensembl:ENST00000263382(transcript)|ensembl:ENST00000672225(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9NVP2|rcsb pdb:5BNX|rcsb pdb:5BO0|dip:DIP-29242N|mint:MINT-8408139(identity) - - caution:This sequence has been withdrawn from Uniprot. figure legend:f5b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2012/07/19 2014/10/16 rogid:Hbm36aMIq0BwSxCOLnxRl3vyYZY9606 rogid:gG2Px6QOw95EohRaaWivH7GrSr09606 intact-crc:09AA3452D8595E27|rigid:/FB4DUXXtQ4u2l1xrQGRaiR8ydY false flag tag:?-?(MINT-8408132)|mutation decreasing interaction:1042-1042(MINT-8408134) - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IWY9 uniprotkb:Q9Y294 intact:EBI-726307|uniprotkb:Q6NYD0|uniprotkb:Q7Z7L5|uniprotkb:Q969N3|ensembl:ENSP00000348564 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 psi-mi:cdan1_human(display_long)|uniprotkb:CDAN1(gene name)|psi-mi:CDAN1(display_short)|uniprotkb:UNQ664/PRO1295(orf name) psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ask et al. (2012) doi:10.1038/emboj.2012.55|pubmed:22407294|imex:IM-18773|mint:MINT-8388457 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7785406|mint:MINT-8408119|imex:IM-18773-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_612486.2|dip:DIP-24225N|ensembl:ENSG00000140326(gene)|ensembl:ENST00000356231(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0008104"(protein localization)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031497"(chromatin assembly)|interpro:IPR028171|interpro:IPR040031|mint:Q8IWY9|mint:MINT-8408123(identity) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F|mint:MINT-8408121(identity) - - caution:This sequence has been withdrawn from Uniprot. figure legend:f5b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2012/07/19 2014/10/16 rogid:Hbm36aMIq0BwSxCOLnxRl3vyYZY9606 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 intact-crc:09AA3452D8595E27|rigid:/FB4DUXXtQ4u2l1xrQGRaiR8ydY false flag tag:?-?(MINT-8408132)|mutation decreasing interaction:1042-1042(MINT-8408134) - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IWY9 uniprotkb:Q9NVP2 intact:EBI-726307|uniprotkb:Q6NYD0|uniprotkb:Q7Z7L5|uniprotkb:Q969N3|ensembl:ENSP00000348564 intact:EBI-1055650|uniprotkb:Q53G51|uniprotkb:Q9NVZ0|ensembl:ENSP00000263382|ensembl:ENSP00000499863 psi-mi:cdan1_human(display_long)|uniprotkb:CDAN1(gene name)|psi-mi:CDAN1(display_short)|uniprotkb:UNQ664/PRO1295(orf name) psi-mi:asf1b_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog B(gene name synonym)|uniprotkb:CCG1-interacting factor A-II(gene name synonym)|uniprotkb:ASF1B(gene name)|psi-mi:ASF1B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ask et al. (2012) doi:10.1038/emboj.2012.55|pubmed:22407294|imex:IM-18773|mint:MINT-8388457 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7785428|mint:MINT-8408142|imex:IM-18773-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_612486.2|dip:DIP-24225N|ensembl:ENSG00000140326(gene)|ensembl:ENST00000356231(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0008104"(protein localization)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031497"(chromatin assembly)|interpro:IPR028171|interpro:IPR040031|mint:Q8IWY9|mint:MINT-8408148(identity) refseq:NP_060624.1|ensembl:ENSG00000105011(gene)|ensembl:ENSG00000288210(gene)|ensembl:ENST00000263382(transcript)|ensembl:ENST00000672225(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9NVP2|rcsb pdb:5BNX|rcsb pdb:5BO0|dip:DIP-29242N|mint:MINT-8408144(identity) - - caution:This sequence has been withdrawn from Uniprot. figure legend:f5b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2012/07/19 2014/10/16 rogid:Hbm36aMIq0BwSxCOLnxRl3vyYZY9606 rogid:gG2Px6QOw95EohRaaWivH7GrSr09606 intact-crc:B42F0E21229B5759|rigid:/FB4DUXXtQ4u2l1xrQGRaiR8ydY false flag tag:?-?(MINT-8408151)|mutation decreasing interaction:714-714(MINT-8408149) - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IWY9 uniprotkb:Q9Y294 intact:EBI-726307|uniprotkb:Q6NYD0|uniprotkb:Q7Z7L5|uniprotkb:Q969N3|ensembl:ENSP00000348564 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 psi-mi:cdan1_human(display_long)|uniprotkb:CDAN1(gene name)|psi-mi:CDAN1(display_short)|uniprotkb:UNQ664/PRO1295(orf name) psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Ask et al. (2012) doi:10.1038/emboj.2012.55|pubmed:22407294|imex:IM-18773|mint:MINT-8388457 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7785428|mint:MINT-8408142|imex:IM-18773-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_612486.2|dip:DIP-24225N|ensembl:ENSG00000140326(gene)|ensembl:ENST00000356231(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0008104"(protein localization)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031497"(chromatin assembly)|interpro:IPR028171|interpro:IPR040031|mint:Q8IWY9|mint:MINT-8408148(identity) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F|mint:MINT-8408146(identity) - - caution:This sequence has been withdrawn from Uniprot. figure legend:f5b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line) - 2012/07/19 2014/10/16 rogid:Hbm36aMIq0BwSxCOLnxRl3vyYZY9606 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 intact-crc:B42F0E21229B5759|rigid:/FB4DUXXtQ4u2l1xrQGRaiR8ydY false flag tag:?-?(MINT-8408151)|mutation decreasing interaction:714-714(MINT-8408149) - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)