#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9UIL1 uniprotkb:O43493 intact:EBI-2686537|uniprotkb:Q7L2Y0|uniprotkb:Q9BZB2|uniprotkb:Q96JY9|uniprotkb:Q7Z4P2|uniprotkb:B7WPH7|uniprotkb:Q6P5T9|intact:EBI-2812448|uniprotkb:D3DNY7|uniprotkb:E9PB65 intact:EBI-1752146|uniprotkb:B8ZZ88|uniprotkb:O15282|uniprotkb:O43492|uniprotkb:O43499|uniprotkb:O43500|uniprotkb:O43501|uniprotkb:Q53G68|uniprotkb:Q53GV2|uniprotkb:Q6MZV1|uniprotkb:Q6ZTM7|uniprotkb:Q8N6T8|uniprotkb:Q92760|uniprotkb:Q96QL2|uniprotkb:B2R686|uniprotkb:D6W5K3|uniprotkb:F8WBK2|ensembl:ENSP00000366603|uniprotkb:F8W8W7|uniprotkb:J3KQ45 psi-mi:scoc_human(display_long)|uniprotkb:SCOCO(gene name synonym)|uniprotkb:HRIHFB2072(orf name)|uniprotkb:SCOC(gene name)|psi-mi:SCOC(display_short) psi-mi:tgon2_human(display_long)|uniprotkb:TGOLN2(gene name)|psi-mi:TGOLN2(display_short)|uniprotkb:TGN46(gene name synonym)|uniprotkb:TGN51(gene name synonym)|uniprotkb:Trans-Golgi network glycoprotein 46(gene name synonym)|uniprotkb:Trans-Golgi network glycoprotein 48(gene name synonym)|uniprotkb:Trans-Golgi network glycoprotein 51(gene name synonym)|uniprotkb:Trans-Golgi network protein 2(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) McKnight et al. (2012) doi:10.1038/emboj.2012.36|pubmed:22354037|imex:IM-18766|mint:MINT-8398502 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7699345|mint:MINT-8398546|imex:IM-18766-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001146918.1|refseq:NP_001146956.1|refseq:NP_001147024.1|refseq:NP_001147057.1|refseq:NP_001147107.1|refseq:NP_001147135.1|refseq:NP_001147162.1|refseq:NP_115936.2|interpro:IPR019357|reactome:R-HSA-6811440|rcsb pdb:4BWD|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0000139"(Golgi membrane)|mint:MINT-8398548(identity) refseq:NP_001193769.1|refseq:NP_001193770.1|refseq:NP_001193773.1|refseq:NP_006455.2|ensembl:ENSG00000152291(gene)|ensembl:ENST00000377386(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|mint:O43493|rcsb pdb:6YAF|reactome:R-HSA-381426|reactome:R-HSA-432722|reactome:R-HSA-6811440|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8957275|mint:MINT-8398549(identity) go:"GO:0005794"(Golgi apparatus) - - figure legend:f3b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/10/11 2019/09/20 rogid:l1hHXnWtTNJbZZBNyDtExzt5SSQ9606 rogid:kKxYdkMYOAseMtlPB5SgXbAyHc89606 intact-crc:D2904E5982388BE7|rigid:G819QSJfTiiqolS9BY3+f0NOF9w false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q99689 uniprotkb:Q9UIL1 intact:EBI-396435|uniprotkb:O00679|uniprotkb:O00728|uniprotkb:Q6IBI7|ensembl:ENSP00000278919|ensembl:ENSP00000497070 intact:EBI-2686537|uniprotkb:Q7L2Y0|uniprotkb:Q9BZB2|uniprotkb:Q96JY9|uniprotkb:Q7Z4P2|uniprotkb:B7WPH7|uniprotkb:Q6P5T9|intact:EBI-2812448|uniprotkb:D3DNY7|uniprotkb:E9PB65 psi-mi:fez1_human(display_long)|uniprotkb:FEZ1(gene name)|psi-mi:FEZ1(display_short)|uniprotkb:Zygin-1(gene name synonym)|uniprotkb:Zygin I(gene name synonym) psi-mi:scoc_human(display_long)|uniprotkb:SCOCO(gene name synonym)|uniprotkb:HRIHFB2072(orf name)|uniprotkb:SCOC(gene name)|psi-mi:SCOC(display_short) psi-mi:"MI:0416"(fluorescence microscopy) McKnight et al. (2012) doi:10.1038/emboj.2012.36|pubmed:22354037|imex:IM-18766|mint:MINT-8398502 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7699371|mint:MINT-8398570|imex:IM-18766-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005094.1|refseq:NP_072043.1|refseq:XP_005271791.1|refseq:XP_005271792.1|ensembl:ENSG00000149557(gene)|ensembl:ENST00000278919(transcript)|ensembl:ENST00000648911(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051654"(establishment of mitochondrion localization)|go:"GO:0061881"(positive regulation of anterograde axonal transport of mitochondrion)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR011680(FEZ-like)|interpro:IPR015642(Fasciculation and elongation protein zeta 1)|dip:DIP-32494N|mint:MINT-8398575(identity) refseq:NP_001146918.1|refseq:NP_001146956.1|refseq:NP_001147024.1|refseq:NP_001147057.1|refseq:NP_001147107.1|refseq:NP_001147135.1|refseq:NP_001147162.1|refseq:NP_115936.2|interpro:IPR019357|reactome:R-HSA-6811440|rcsb pdb:4BWD|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0000139"(Golgi membrane)|mint:MINT-8398573(identity) - - - figure legend:f4e|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/10/11 2014/10/16 rogid:RKDxw2P5XBHcRtf1VQxY1t3bHVU9606 rogid:l1hHXnWtTNJbZZBNyDtExzt5SSQ9606 intact-crc:C7D716073A22254E|rigid:6MLkWOgihgU/sEczVbEbj6FhM8A false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9UIL1 uniprotkb:Q9GZQ8 intact:EBI-2686537|uniprotkb:Q7L2Y0|uniprotkb:Q9BZB2|uniprotkb:Q96JY9|uniprotkb:Q7Z4P2|uniprotkb:B7WPH7|uniprotkb:Q6P5T9|intact:EBI-2812448|uniprotkb:D3DNY7|uniprotkb:E9PB65 intact:EBI-373144|uniprotkb:Q6NW02|intact:EBI-28979688|ensembl:ENSP00000268607|ensembl:ENSP00000498476 psi-mi:scoc_human(display_long)|uniprotkb:SCOCO(gene name synonym)|uniprotkb:HRIHFB2072(orf name)|uniprotkb:SCOC(gene name)|psi-mi:SCOC(display_short) psi-mi:mlp3b_human(display_long)|uniprotkb:MAP1LC3B(gene name)|psi-mi:MAP1LC3B(display_short)|uniprotkb:MAP1ALC3(gene name synonym)|uniprotkb:Microtubule-associated protein 1 light chain 3 beta(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 B(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 2(gene name synonym)|uniprotkb:Autophagy-related protein LC3 B(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 B(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) McKnight et al. (2012) doi:10.1038/emboj.2012.36|pubmed:22354037|imex:IM-18766|mint:MINT-8398502 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7699358|mint:MINT-8398560|imex:IM-18766-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001146918.1|refseq:NP_001146956.1|refseq:NP_001147024.1|refseq:NP_001147057.1|refseq:NP_001147107.1|refseq:NP_001147135.1|refseq:NP_001147162.1|refseq:NP_115936.2|interpro:IPR019357|reactome:R-HSA-6811440|rcsb pdb:4BWD|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0000139"(Golgi membrane)|mint:MINT-8398563(identity) ensembl:ENSP00000268607|ensembl:ENSP00000498476|refseq:NP_073729.1|ensembl:ENSG00000140941(gene)|ensembl:ENST00000268607(transcript)|ensembl:ENST00000650688(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0005739"(mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031090"(organelle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0097001"(ceramide binding)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|mint:Q9GZQ8|rcsb pdb:1V49|rcsb pdb:2LUE|rcsb pdb:2N9X|rcsb pdb:2ZJD|rcsb pdb:3VTU|rcsb pdb:3VTV|rcsb pdb:3VTW|rcsb pdb:3WAO|rcsb pdb:3X0W|rcsb pdb:4WAA|rcsb pdb:5D94|rcsb pdb:5DCN|rcsb pdb:5GMV|rcsb pdb:5MS2|rcsb pdb:5MS5|rcsb pdb:5MS6|rcsb pdb:5V4K|rcsb pdb:5W9A|rcsb pdb:5XAC|rcsb pdb:5XAD|rcsb pdb:5XAE|rcsb pdb:6J04|rcsb pdb:6LAN|reactome:R-HSA-1632852|reactome:R-HSA-5205685|reactome:R-HSA-8854214|reactome:R-HSA-8934903|reactome:R-HSA-9664873|reactome:R-HSA-9679504|reactome:R-HSA-9694676|dip:DIP-29760N|mint:MINT-8398565(identity) go:"GO:0005794"(Golgi apparatus) - - figure legend:f3c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/10/11 2014/10/16 rogid:l1hHXnWtTNJbZZBNyDtExzt5SSQ9606 rogid:yUk3FGI9csW9DNlqWkewtqM2VN09606 intact-crc:80BD2EB58D5CE174|rigid:icqbdrdi4KHYvjk569y5WKnIof8 false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q62625 uniprotkb:Q9UIL1 intact:EBI-2935980|ensembl:ENSRNOP00000062130|uniprotkb:Q6XVN7 intact:EBI-2686537|uniprotkb:Q7L2Y0|uniprotkb:Q9BZB2|uniprotkb:Q96JY9|uniprotkb:Q7Z4P2|uniprotkb:B7WPH7|uniprotkb:Q6P5T9|intact:EBI-2812448|uniprotkb:D3DNY7|uniprotkb:E9PB65 psi-mi:mlp3b_rat(display_long)|uniprotkb:Map1lc3b(gene name)|psi-mi:Map1lc3b(display_short)|uniprotkb:Map1alc3(gene name synonym)|uniprotkb:Map1lc3(gene name synonym)|uniprotkb:Autophagy-related protein LC3 B(gene name synonym)|uniprotkb:Autophagy-related ubiquitin-like modifier LC3 B(gene name synonym)|uniprotkb:MAP1 light chain 3-like protein 2(gene name synonym)|uniprotkb:MAP1A/MAP1B light chain 3 B(gene name synonym)|uniprotkb:Microtubule-associated protein 1 light chain 3 beta(gene name synonym) psi-mi:scoc_human(display_long)|uniprotkb:SCOCO(gene name synonym)|uniprotkb:HRIHFB2072(orf name)|uniprotkb:SCOC(gene name)|psi-mi:SCOC(display_short) psi-mi:"MI:0416"(fluorescence microscopy) McKnight et al. (2012) doi:10.1038/emboj.2012.36|pubmed:22354037|imex:IM-18766|mint:MINT-8398502 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7699412|mint:MINT-8399803|imex:IM-18766-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0008017"(microtubule binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0012505"(endomembrane system)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044754"(autolysosome)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR004241("Light chain 3 (LC3)")|interpro:IPR029071|rcsb pdb:1UGM|rcsb pdb:2K6Q|rcsb pdb:2Z0D|rcsb pdb:2Z0E|rcsb pdb:2ZZP|reactome:R-RNO-1632852|reactome:R-RNO-5205685|reactome:R-RNO-8854214|reactome:R-RNO-8934903|reactome:R-RNO-9664873|go:"GO:0000423"(mitophagy)|ensembl:ENSRNOG00000017905(gene)|ensembl:ENSRNOT00000067141(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|rgd:621315|refseq:NP_074058.2|refseq:XP_017456840.1|mint:MINT-8399806(identity) refseq:NP_001146918.1|refseq:NP_001146956.1|refseq:NP_001147024.1|refseq:NP_001147057.1|refseq:NP_001147107.1|refseq:NP_001147135.1|refseq:NP_001147162.1|refseq:NP_115936.2|interpro:IPR019357|reactome:R-HSA-6811440|rcsb pdb:4BWD|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0000139"(Golgi membrane)|mint:MINT-8399808(identity) go:"GO:0005794"(Golgi apparatus) - - figure legend:f3c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/10/11 2014/10/16 rogid:5KiMxcCBOwyxOHUK7zRN2Yte64g10116 rogid:l1hHXnWtTNJbZZBNyDtExzt5SSQ9606 intact-crc:2103A28D52CDBDD1|rigid:CPHCHlom6FMAeB+TG6OyaMGFscg false green fluorescent protein tag:?-?(MINT-8399811) - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q99689 uniprotkb:Q9P2Y5 intact:EBI-396435|uniprotkb:O00679|uniprotkb:O00728|uniprotkb:Q6IBI7|ensembl:ENSP00000278919|ensembl:ENSP00000497070 intact:EBI-2952704|uniprotkb:B3KTC1|ensembl:ENSP00000348455|uniprotkb:O00392 psi-mi:fez1_human(display_long)|uniprotkb:FEZ1(gene name)|psi-mi:FEZ1(display_short)|uniprotkb:Zygin-1(gene name synonym)|uniprotkb:Zygin I(gene name synonym) psi-mi:uvrag_human(display_long)|uniprotkb:UVRAG(gene name)|psi-mi:UVRAG(display_short)|uniprotkb:p63(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) McKnight et al. (2012) doi:10.1038/emboj.2012.36|pubmed:22354037|imex:IM-18766|mint:MINT-8398502 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7699400|mint:MINT-8398602|imex:IM-18766-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005094.1|refseq:NP_072043.1|refseq:XP_005271791.1|refseq:XP_005271792.1|ensembl:ENSG00000149557(gene)|ensembl:ENST00000278919(transcript)|ensembl:ENST00000648911(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051654"(establishment of mitochondrion localization)|go:"GO:0061881"(positive regulation of anterograde axonal transport of mitochondrion)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR011680(FEZ-like)|interpro:IPR015642(Fasciculation and elongation protein zeta 1)|dip:DIP-32494N|mint:MINT-8398606(identity) go:"GO:0017124"(SH3 domain binding)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051684"(maintenance of Golgi location)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR018791|interpro:IPR035892|mint:Q9P2Y5|rcsb pdb:7BL1|reactome:R-HSA-1632852|reactome:R-HSA-9679504|reactome:R-HSA-9694676|ensembl:ENSG00000198382(gene)|ensembl:ENST00000356136(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006914"(autophagy)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007098"(centrosome cycle)|refseq:NP_003360.2|ensembl:ENSP00000348455|ensembl:ENST00000531818|ensembl:ENSP00000434082|ensembl:ENST00000532130|ensembl:ENSP00000436270|ensembl:ENST00000533454|ensembl:ENSP00000431256|dip:DIP-48652N|mint:MINT-8398604(identity) - - - comment:homomint|comment:mint|figure legend:f7f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/10/11 2014/10/16 rogid:RKDxw2P5XBHcRtf1VQxY1t3bHVU9606 rogid:TDc74eSYcSe2UJdNnKbFv5EBziE9606 intact-crc:D1FD5312E17EBFFB|rigid:FRMijuZ0z8jDDunHyCCmAlN0sFs false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q99689 uniprotkb:O75385 intact:EBI-396435|uniprotkb:O00679|uniprotkb:O00728|uniprotkb:Q6IBI7|ensembl:ENSP00000278919|ensembl:ENSP00000497070 intact:EBI-908831|uniprotkb:Q9UQ28|ensembl:ENSP00000324560 psi-mi:fez1_human(display_long)|uniprotkb:FEZ1(gene name)|psi-mi:FEZ1(display_short)|uniprotkb:Zygin-1(gene name synonym)|uniprotkb:Zygin I(gene name synonym) psi-mi:ulk1_human(display_long)|uniprotkb:ULK1(gene name)|psi-mi:ULK1(display_short)|uniprotkb:KIAA0722(gene name synonym)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Autophagy-related protein 1 homolog(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) McKnight et al. (2012) doi:10.1038/emboj.2012.36|pubmed:22354037|imex:IM-18766|mint:MINT-8398502 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7699435|mint:MINT-8398595|imex:IM-18766-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005094.1|refseq:NP_072043.1|refseq:XP_005271791.1|refseq:XP_005271792.1|ensembl:ENSG00000149557(gene)|ensembl:ENST00000278919(transcript)|ensembl:ENST00000648911(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051654"(establishment of mitochondrion localization)|go:"GO:0061881"(positive regulation of anterograde axonal transport of mitochondrion)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR011680(FEZ-like)|interpro:IPR015642(Fasciculation and elongation protein zeta 1)|dip:DIP-32494N|mint:MINT-8398599(identity) refseq:NP_003556.1|dip:DIP-35196N|ensembl:ENSG00000177169(gene)|ensembl:ENST00000321867(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008104"(protein localization)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:O75385|rcsb pdb:4WNO|rcsb pdb:4WNP|rcsb pdb:5CI7|rcsb pdb:6HYO|rcsb pdb:6MNH|rcsb pdb:6QAS|reactome:R-HSA-1632852|reactome:R-HSA-8854214|reactome:R-HSA-8876198|reactome:R-HSA-8934903|mint:MINT-8398597(identity) - - - figure legend:f6b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2012/10/11 2014/10/16 rogid:RKDxw2P5XBHcRtf1VQxY1t3bHVU9606 rogid:Q27JsEOr//zWM8N4jycsZdzbALM9606 intact-crc:4A0EABDA1B06E29D|rigid:wWob5qHE5jwhkgICIFhZpPLd4zM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)