#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
ensembl:ENSMUSG00000004872	uniprotkb:Q61188	intact:EBI-6049930	intact:EBI-904311|uniprotkb:Q99L74|intact:EBI-2526787|uniprotkb:Q9R090|ensembl:ENSMUSP00000080419	psi-mi:pax3_mouse_gene(display_short)|psi-mi:ENSMUSG00000004872(display_long)	psi-mi:ezh2_mouse(display_long)|uniprotkb:Ezh2(gene name)|psi-mi:Ezh2(display_short)|uniprotkb:Enx1h(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050111|imex:IM-17309-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_031997.2|dip:DIP-29524N|ensembl:ENSMUSG00000029687(gene)|ensembl:ENSMUST00000081721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006348"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0048511"(rhythmic process)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q61188|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	figure legend:Supp. Fig. 3B|comment:Recruitment of RING1B and EZH2 was retained following MG132 treatment|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	-	rogid:g2SeyOX9aEEKepn2fS3eprvcixg10090	intact-crc:8D4E9BF2FADA56FD	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
intact:EBI-6049932	uniprotkb:Q9CQJ4	-	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	psi-mi:sox1_mouse_gene(display_short)|psi-mi:EBI-6049932(display_long)	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050011|imex:IM-17309-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0919"(acceptor)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	comment:"Not currently in Ensembl (03/12)"	-	figure legend:Fig. 1A, Supp. Fig. 7B|comment:Interaction not observed in absence of Polycomb protein EED. RYBP knockdown led to substantially reduced levels of H2AK119u1 reduced occupancy of RING1B on this gene.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	-	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	intact-crc:B8658A29D089B6D6	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSMUSG00000038236	uniprotkb:Q61188	intact:EBI-6049922	intact:EBI-904311|uniprotkb:Q99L74|intact:EBI-2526787|uniprotkb:Q9R090|ensembl:ENSMUSP00000080419	psi-mi:hxa7_mouse_gene(display_short)|psi-mi:ENSMUSG00000038236(display_long)	psi-mi:ezh2_mouse(display_long)|uniprotkb:Ezh2(gene name)|psi-mi:Ezh2(display_short)|uniprotkb:Enx1h(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050087|imex:IM-17309-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_031997.2|dip:DIP-29524N|ensembl:ENSMUSG00000029687(gene)|ensembl:ENSMUST00000081721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006348"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0048511"(rhythmic process)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q61188|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	figure legend:Supp. Fig.3B|comment:Interaction not observed in absence of Polycomb protein EED. Recruitment of RING1B and EZH2 was retained following MG132 treatment|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	-	rogid:g2SeyOX9aEEKepn2fS3eprvcixg10090	intact-crc:8A8F5C6BD98F0E7A	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q61188	ensembl:ENSMUSG00000029646	intact:EBI-904311|uniprotkb:Q99L74|intact:EBI-2526787|uniprotkb:Q9R090|ensembl:ENSMUSP00000080419	intact:EBI-6049920	psi-mi:ezh2_mouse(display_long)|uniprotkb:Ezh2(gene name)|psi-mi:Ezh2(display_short)|uniprotkb:Enx1h(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)	psi-mi:cdx2_mouse_gene(display_short)|psi-mi:ENSMUSG00000029646(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050073|imex:IM-17309-32	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_031997.2|dip:DIP-29524N|ensembl:ENSMUSG00000029687(gene)|ensembl:ENSMUST00000081721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006348"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0048511"(rhythmic process)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q61188|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	-	figure legend:Supp. Fig. 3B|comment:Interaction not observed in absence of Polycomb protein EED. Recruitment of RING1B and EZH2 was retained following MG132 treatment|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:g2SeyOX9aEEKepn2fS3eprvcixg10090	-	intact-crc:7607B292FBECA296	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q9CQJ4	ensembl:ENSMUSG00000021944	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	intact:EBI-1790676	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:gata4_mouse_gene(display_short)|psi-mi:ENSMUSG00000021944(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6049991|imex:IM-17309-19	-	-	psi-mi:"MI:0919"(acceptor)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	-	figure legend:Fig. 1A, Supp. Fig. 7B|comment:Interaction not observed in absence of Polycomb protein EED. RYBP knockdown led to substantially reduced levels of H2AK119u1 reduced occupancy of RING1B on this gene.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	-	intact-crc:BFB60914CBF48E12	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSMUSG00000004872	uniprotkb:Q9CQJ4	intact:EBI-6049930	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	psi-mi:pax3_mouse_gene(display_short)|psi-mi:ENSMUSG00000004872(display_long)	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050006|imex:IM-17309-22	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0919"(acceptor)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 1A, Supp. Fig. 7B|comment:Interaction not observed in absence of Polycomb protein EED. RYBP knockdown led to substantially reduced levels of H2AK119u1 reduced occupancy of RING1B on this gene.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	-	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	intact-crc:7CB1654BB5067F2E	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSMUSG00000038236	uniprotkb:Q9CQJ4	intact:EBI-6049922	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	psi-mi:hxa7_mouse_gene(display_short)|psi-mi:ENSMUSG00000038236(display_long)	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6049981|imex:IM-17309-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0919"(acceptor)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 1A, Supp. Fig. 7B|comment:Interaction not observed in absence of Polycomb protein EED. RYBP knockdown led to substantially reduced levels of H2AK119u1 reduced occupancy of RING1B on this gene.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	-	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	intact-crc:774E2E0E4797C849	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q9CQJ4	ensembl:ENSMUSG00000048450	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	intact:EBI-6049924	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:msx1_mouse_gene(display_short)|psi-mi:ENSMUSG00000048450(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6049986|imex:IM-17309-18	-	-	psi-mi:"MI:0919"(acceptor)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	-	figure legend:Fig. 1A, Supp. Fig. 7B|comment:Interaction not observed in absence of Polycomb protein EED. RYBP knockdown led to substantially reduced levels of H2AK119u1 reduced occupancy of RING1B on this gene.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	-	intact-crc:FD424EB5180D2598	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSMUSG00000073043	uniprotkb:Q9CQJ4	intact:EBI-6049928	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	psi-mi:atoh1_mouse_gene(display_short)|psi-mi:ENSMUSG00000073043(display_long)	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050001|imex:IM-17309-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0919"(acceptor)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 1A, Supp Fig. 7B|comment:Interaction not observed in absence of Polycomb protein EED. RYBP knockdown led to substantially reduced levels of H2AK119u1 reduced occupancy of RING1B on this gene.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	-	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	intact-crc:C9B6BC7FABC34791	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSMUSG00000021944	uniprotkb:Q8CCI5	intact:EBI-1790676	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	psi-mi:gata4_mouse_gene(display_short)|psi-mi:ENSMUSG00000021944(display_long)	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6095895|imex:IM-17309-42	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 6A Supp Fig. 6A, 6B|comment:Interaction was unaffected following conditional depletion of H3K27me3 and in MG132-treated cells demonstrating that H2AK119u1 is not required for RYBP occupancy.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	-	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	intact-crc:30A8EFBD82D2A5C7	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSMUSG00000048450	uniprotkb:Q8CCI5	intact:EBI-6049924	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	psi-mi:msx1_mouse_gene(display_short)|psi-mi:ENSMUSG00000048450(display_long)	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6095890|imex:IM-17309-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 6A Supp Fig. 6A, 6B|comment:Interaction was unaffected following conditional depletion of H3K27me3 and in MG132-treated cells demonstrating that H2AK119u1 is not required for RYBP occupancy.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	-	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	intact-crc:F7093C442958D73F	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q8CCI5	intact:EBI-6049932	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	-	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:sox1_mouse_gene(display_short)|psi-mi:EBI-6049932(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6095927|imex:IM-17309-46	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	-	-	-	comment:"Not currently in Ensembl (03/12)"	figure legend:Fig. 6A Supp Fig. 6A, 6B|comment:Interaction was unaffected following conditional depletion of H3K27me3 and in MG132-treated cells demonstrating that H2AK119u1 is not required for RYBP occupancy.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	-	intact-crc:1FFD190082BD8DBD	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSMUSG00000004872	uniprotkb:Q8CCI5	intact:EBI-6049930	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	psi-mi:pax3_mouse_gene(display_short)|psi-mi:ENSMUSG00000004872(display_long)	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6095922|imex:IM-17309-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 6A Supp Fig. 6A, 6B|comment:Interaction was unaffected following conditional depletion of H3K27me3 and in MG132-treated cells demonstrating that H2AK119u1 is not required for RYBP occupancy.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	-	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	intact-crc:2CF7914F73EE35C2	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q8CCI5	ensembl:ENSMUSG00000027434	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	intact:EBI-6049926	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:nkx22_mouse_gene(display_short)|psi-mi:ENSMUSG00000027434(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6095904|imex:IM-17309-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	-	-	-	-	figure legend:Fig. 6A Supp Fig. 6A, 6B|comment:Interaction was unaffected following conditional depletion of H3K27me3 and in MG132-treated cells demonstrating that H2AK119u1 is not required for RYBP occupancy.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	-	intact-crc:76E717B5957158C7	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q8CCI5	ensembl:ENSMUSG00000038236	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	intact:EBI-6049922	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:hxa7_mouse_gene(display_short)|psi-mi:ENSMUSG00000038236(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6095885|imex:IM-17309-40	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	-	-	-	-	figure legend:Fig. 6A Supp Fig. 6A, 6B|comment:Interaction was unaffected following conditional depletion of H3K27me3 and in MG132-treated cells demonstrating that H2AK119u1 is not required for RYBP occupancy.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	-	intact-crc:27B263DEC489390E	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:P23798	ensembl:ENSMUSG00000048450	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-6049924	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:msx1_mouse_gene(display_short)|psi-mi:ENSMUSG00000048450(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050026|imex:IM-17309-26	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	-	-	-	-	figure legend:Fig. 1A, Supp. Fig. 3B|comment:Interaction not observed in absence of Polycomb protein EED. Recruitment of RING1B and EZH2 was retained following MG132 treatment|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	-	intact-crc:0E6F42460FA67105	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:P23798	ensembl:ENSMUSG00000029646	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-6049920	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:cdx2_mouse_gene(display_short)|psi-mi:ENSMUSG00000029646(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050016|imex:IM-17309-24	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	-	-	-	-	figure legend:Supp. Fig. 3B|comment:Recruitment of RING1B and EZH2 was retained following MG132 treatment|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	-	intact-crc:5D6B408252CFB419	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q61188	ensembl:ENSMUSG00000027434	intact:EBI-904311|uniprotkb:Q99L74|intact:EBI-2526787|uniprotkb:Q9R090|ensembl:ENSMUSP00000080419	intact:EBI-6049926	psi-mi:ezh2_mouse(display_long)|uniprotkb:Ezh2(gene name)|psi-mi:Ezh2(display_short)|uniprotkb:Enx1h(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)	psi-mi:nkx22_mouse_gene(display_short)|psi-mi:ENSMUSG00000027434(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050104|imex:IM-17309-36	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_031997.2|dip:DIP-29524N|ensembl:ENSMUSG00000029687(gene)|ensembl:ENSMUST00000081721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006348"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0048511"(rhythmic process)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q61188|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	-	figure legend:Supp. Fig. 3B|comment:Recruitment of RING1B and EZH2 was retained following MG132 treatment|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:g2SeyOX9aEEKepn2fS3eprvcixg10090	-	intact-crc:870269C9BF3A5815	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSMUSG00000027434	uniprotkb:P23798	intact:EBI-6049926	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	psi-mi:nkx22_mouse_gene(display_short)|psi-mi:ENSMUSG00000027434(display_long)	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050036|imex:IM-17309-28	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 1A, Supp. Fig. 3B|comment:Interaction not observed in absence of Polycomb protein EED. Recruitment of RING1B and EZH2 was retained following MG132 treatment|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	-	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	intact-crc:5769FEC86C4CA858	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSMUSG00000029646	uniprotkb:Q8CCI5	intact:EBI-6049920	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	psi-mi:cdx2_mouse_gene(display_short)|psi-mi:ENSMUSG00000029646(display_long)	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6095880|imex:IM-17309-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 6A Supp Fig. 6A, 6B|comment:Interaction was unaffected following conditional depletion of H3K27me3 and in MG132-treated cells demonstrating that H2AK119u1 is not required for RYBP occupancy.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	-	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	intact-crc:CE53BCF136674171	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:P23798	ensembl:ENSMUSG00000021944	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-1790676	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:gata4_mouse_gene(display_short)|psi-mi:ENSMUSG00000021944(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050031|imex:IM-17309-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	-	-	-	-	figure legend:Fig. 1A, Supp. Fig. 3B|comment:Interaction not observed in absence of Polycomb protein EED. Recruitment of RING1B and EZH2 was retained following MG132 treatment|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	-	intact-crc:62496F053C43AB69	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:P23798	ensembl:ENSMUSG00000073043	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-6049928	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:atoh1_mouse_gene(display_short)|psi-mi:ENSMUSG00000073043(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050041|imex:IM-17309-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	-	-	-	-	figure legend:Fig. 1A|comment:Interaction not observed in absence of Polycomb protein EED. Recruitment of RING1B and EZH2 was retained following MG132 treatment|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	-	intact-crc:6E2B197490356852	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSMUSG00000073043	uniprotkb:Q8CCI5	intact:EBI-6049928	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	psi-mi:atoh1_mouse_gene(display_short)|psi-mi:ENSMUSG00000073043(display_long)	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6095909|imex:IM-17309-44	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 6A Supp Fig. 6A, 6B|comment:Interaction was unaffected following conditional depletion of H3K27me3 and in MG132-treated cells demonstrating that H2AK119u1 is not required for RYBP occupancy.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	-	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	intact-crc:1518AAA7B0C55EE5	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:Q61188	intact:EBI-6049932	intact:EBI-904311|uniprotkb:Q99L74|intact:EBI-2526787|uniprotkb:Q9R090|ensembl:ENSMUSP00000080419	-	psi-mi:ezh2_mouse(display_long)|uniprotkb:Ezh2(gene name)|psi-mi:Ezh2(display_short)|uniprotkb:Enx1h(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)	psi-mi:sox1_mouse_gene(display_short)|psi-mi:EBI-6049932(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050116|imex:IM-17309-38	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0919"(acceptor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_031997.2|dip:DIP-29524N|ensembl:ENSMUSG00000029687(gene)|ensembl:ENSMUST00000081721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006348"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0048511"(rhythmic process)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q61188|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	comment:"Not currently in Ensembl (03/12)"	figure legend:Supp Fig. 3B|comment:Interaction not observed in absence of Polycomb protein EED. Recruitment of RING1B and EZH2 was retained following MG132 treatment|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:g2SeyOX9aEEKepn2fS3eprvcixg10090	-	intact-crc:D717E666FC648257	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSMUSG00000027434	uniprotkb:Q9CQJ4	intact:EBI-6049926	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	psi-mi:nkx22_mouse_gene(display_short)|psi-mi:ENSMUSG00000027434(display_long)	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6049996|imex:IM-17309-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0919"(acceptor)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 1A, Supp. Fig. 7B|comment:Interaction not observed in absence of Polycomb protein EED. RYBP knockdown led to substantially reduced levels of H2AK119u1 reduced occupancy of RING1B on this gene.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	-	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	intact-crc:2C464F5B33FC99B1	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:P23798	intact:EBI-6049932	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	-	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:sox1_mouse_gene(display_short)|psi-mi:EBI-6049932(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050062|imex:IM-17309-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	-	-	-	comment:"Not currently in Ensembl (03/12)"	figure legend:Fig. 1A|comment:Recruitment of RING1B and EZH2 was retained following MG132 treatment|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	-	intact-crc:3402D75590934804	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSMUSG00000004872	uniprotkb:P23798	intact:EBI-6049930	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	psi-mi:pax3_mouse_gene(display_short)|psi-mi:ENSMUSG00000004872(display_long)	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050046|imex:IM-17309-30	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 1A, Supp. Fig. 3B|comment:Interaction not observed in absence of Polycomb protein EED. Recruitment of RING1B and EZH2 was retained following MG132 treatment|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	-	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	intact-crc:B3F959A2EF59D2DF	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:P23798	ensembl:ENSMUSG00000038236	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-6049922	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:hxa7_mouse_gene(display_short)|psi-mi:ENSMUSG00000038236(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050021|imex:IM-17309-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	-	-	-	-	figure legend:Supp. Fig.3B|comment:Recruitment of RING1B and EZH2 was retained following MG132 treatment|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	-	intact-crc:CAC962062921950A	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSMUSG00000048450	uniprotkb:Q61188	intact:EBI-6049924	intact:EBI-904311|uniprotkb:Q99L74|intact:EBI-2526787|uniprotkb:Q9R090|ensembl:ENSMUSP00000080419	psi-mi:msx1_mouse_gene(display_short)|psi-mi:ENSMUSG00000048450(display_long)	psi-mi:ezh2_mouse(display_long)|uniprotkb:Ezh2(gene name)|psi-mi:Ezh2(display_short)|uniprotkb:Enx1h(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050092|imex:IM-17309-34	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_031997.2|dip:DIP-29524N|ensembl:ENSMUSG00000029687(gene)|ensembl:ENSMUST00000081721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006348"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0048511"(rhythmic process)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q61188|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	figure legend:Supp. Fig. 3B|comment:Recruitment of RING1B and EZH2 was retained following MG132 treatment|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	-	rogid:g2SeyOX9aEEKepn2fS3eprvcixg10090	intact-crc:30D880161A25F527	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSMUSG00000029646	uniprotkb:Q9CQJ4	intact:EBI-6049920	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	psi-mi:cdx2_mouse_gene(display_short)|psi-mi:ENSMUSG00000029646(display_long)	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6049967|imex:IM-17309-16	-	-	psi-mi:"MI:0919"(acceptor)	psi-mi:"MI:0919"(acceptor)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 1A, Supp. Fig. 7B|comment:Interaction not observed in absence of Polycomb protein EED. RYBP knockdown led to substantially reduced levels of H2AK119u1 and reduced occupancy of RING1B on this gene.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	-	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	intact-crc:E50565FDB29957E8	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
ensembl:ENSMUSG00000021944	uniprotkb:Q61188	intact:EBI-1790676	intact:EBI-904311|uniprotkb:Q99L74|intact:EBI-2526787|uniprotkb:Q9R090|ensembl:ENSMUSP00000080419	psi-mi:gata4_mouse_gene(display_short)|psi-mi:ENSMUSG00000021944(display_long)	psi-mi:ezh2_mouse(display_long)|uniprotkb:Ezh2(gene name)|psi-mi:Ezh2(display_short)|uniprotkb:Enx1h(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050098|imex:IM-17309-35	-	-	psi-mi:"MI:0919"(acceptor)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_031997.2|dip:DIP-29524N|ensembl:ENSMUSG00000029687(gene)|ensembl:ENSMUST00000081721(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006348"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0048511"(rhythmic process)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q61188|rcsb pdb:2QXV|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-3214841|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	figure legend:Supp. Fig. 3B|comment:Recruitment of RING1B and EZH2 was retained following MG132 treatment|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	-	rogid:g2SeyOX9aEEKepn2fS3eprvcixg10090	intact-crc:C454B340D97BE083	false	-	-	-	-	psi-mi:"MI:0088"(primer specific pcr)	psi-mi:"MI:0088"(primer specific pcr)
uniprotkb:P23798	uniprotkb:O55187	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-1216621|uniprotkb:Q149G5|uniprotkb:Q149G6|ensembl:ENSMUSP00000026665	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:cbx4_mouse(display_long)|uniprotkb:Cbx4(gene name)|psi-mi:Cbx4(display_short)|uniprotkb:Pc2(gene name synonym)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:E3 SUMO-protein transferase CBX4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050154|imex:IM-17309-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	refseq:NP_031651.2|ensembl:ENSMUSG00000039989(gene)|ensembl:ENSMUST00000026665(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724	-	-	-	figure legend:Supp. Fig. 4B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse  Neuronal precursor cells/neural stem progenitor cells)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	rogid:zg/JL2JyCY7ulitIBTYeRHPsQmI10090	intact-crc:DC0613A024CB92A1|rigid:quWEulrzdAk3ysqCg8PmBrltxA8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P23798	uniprotkb:O35730	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-929310|ensembl:ENSMUSP00000025183|uniprotkb:Q3U242|uniprotkb:Q3U333|uniprotkb:Q4FK33|uniprotkb:Q63ZX8|uniprotkb:Q921Z8	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:ring1_mouse(display_long)|uniprotkb:Ring1(gene name)|psi-mi:Ring1(display_short)|uniprotkb:Ring1A(gene name synonym)|uniprotkb:Rnf1(gene name synonym)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:Transcription repressor Ring1A(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050154|imex:IM-17309-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	ensembl:ENSMUSG00000024325(gene)|ensembl:ENSMUST00000025183(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|refseq:NP_033092.3|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|interpro:IPR043540|mint:O35730|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	figure legend:Supp. Fig. 4B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse  Neuronal precursor cells/neural stem progenitor cells)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	rogid:QwNPWozHIOz6ecIMradUC2NqbJE10090	intact-crc:DC0613A024CB92A1|rigid:quWEulrzdAk3ysqCg8PmBrltxA8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P23798	uniprotkb:Q9QWH1	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-642357|uniprotkb:O88463|uniprotkb:Q8K5D9|uniprotkb:B1AS98|uniprotkb:B1ASA4|ensembl:ENSMUSP00000030588|ensembl:ENSMUSP00000101690	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:phc2_mouse(display_long)|uniprotkb:p36(gene name synonym)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:Phc2(gene name)|psi-mi:Phc2(display_short)|uniprotkb:Edr2(gene name synonym)|uniprotkb:Ph2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050154|imex:IM-17309-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	refseq:NP_001182012.1|refseq:NP_001182059.1|refseq:NP_061244.1|refseq:XP_006503300.1|refseq:XP_006503301.1|ensembl:ENSMUSG00000028796(gene)|ensembl:ENSMUST00000030588(transcript)|ensembl:ENSMUST00000106080(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q9QWH1|rcsb pdb:2NA1|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|refseq:XP_017175809.1	-	-	-	figure legend:Supp. Fig. 4B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse  Neuronal precursor cells/neural stem progenitor cells)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	rogid:nNgSS7uHUP3sCDlztQJqi2zl2EU10090	intact-crc:DC0613A024CB92A1|rigid:quWEulrzdAk3ysqCg8PmBrltxA8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P23798	uniprotkb:Q8CCI5	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050154|imex:IM-17309-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	-	-	-	figure legend:Supp. Fig. 4B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse  Neuronal precursor cells/neural stem progenitor cells)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	intact-crc:DC0613A024CB92A1|rigid:quWEulrzdAk3ysqCg8PmBrltxA8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P23798	uniprotkb:Q9CQJ4	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050154|imex:IM-17309-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	figure legend:Supp. Fig. 4B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse  Neuronal precursor cells/neural stem progenitor cells)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	intact-crc:DC0613A024CB92A1|rigid:quWEulrzdAk3ysqCg8PmBrltxA8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P23798	uniprotkb:Q8CHP6	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-1216510|uniprotkb:A2RTJ9|uniprotkb:Q3TLV5|ensembl:ENSMUSP00000114916|ensembl:ENSMUSP00000130142	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:phc3_mouse(display_long)|uniprotkb:Phc3(gene name)|psi-mi:Phc3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050154|imex:IM-17309-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	refseq:NP_001159426.1|refseq:NP_700470.2|ensembl:ENSMUSG00000037652(gene)|ensembl:ENSMUST00000129817(transcript)|ensembl:ENSMUST00000168645(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8CHP6|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	figure legend:Supp. Fig. 4B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse  Neuronal precursor cells/neural stem progenitor cells)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	rogid:Rzm3ZzbVX9nIMC2Jah3g4/0P12410090	intact-crc:DC0613A024CB92A1|rigid:quWEulrzdAk3ysqCg8PmBrltxA8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P23798	uniprotkb:Q64028	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-927346|uniprotkb:P70359|uniprotkb:Q64307|uniprotkb:Q8BZ80	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:phc1_mouse(display_long)|uniprotkb:Phc1(gene name)|psi-mi:Phc1(display_short)|uniprotkb:Edr(gene name synonym)|uniprotkb:Edr1(gene name synonym)|uniprotkb:Rae28(gene name synonym)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:RAE-28(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050154|imex:IM-17309-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	refseq:NP_001258508.1|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750|mint:Q64028|dip:DIP-456N	-	-	-	figure legend:Supp. Fig. 4B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse  Neuronal precursor cells/neural stem progenitor cells)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	rogid:z2SieJadS53WlofBWE3/RNMYPnw10090	intact-crc:DC0613A024CB92A1|rigid:quWEulrzdAk3ysqCg8PmBrltxA8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P23798	uniprotkb:Q9QXV1	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-1216641|ensembl:ENSMUSP00000026663	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:cbx8_mouse(display_long)|uniprotkb:Cbx8(gene name)|psi-mi:Cbx8(display_short)|uniprotkb:Pc3(gene name synonym)|uniprotkb:Polycomb 3 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050154|imex:IM-17309-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	refseq:NP_038954.1|ensembl:ENSMUSG00000025578(gene)|ensembl:ENSMUST00000026663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|rcsb pdb:2DNV|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724	-	-	-	figure legend:Supp. Fig. 4B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse  Neuronal precursor cells/neural stem progenitor cells)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	rogid:cLpux9+wXJIOUI0M01emXGUVM6c10090	intact-crc:DC0613A024CB92A1|rigid:quWEulrzdAk3ysqCg8PmBrltxA8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P23798	uniprotkb:P30658	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-360174|uniprotkb:O35731|uniprotkb:A2ABG2|ensembl:ENSMUSP00000026662|uniprotkb:Q8CIA0	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:cbx2_mouse(display_long)|uniprotkb:Cbx2(gene name)|psi-mi:Cbx2(display_short)|uniprotkb:M33(gene name synonym)|uniprotkb:Modifier 3 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050154|imex:IM-17309-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	ensembl:ENSMUSG00000025577(gene)|ensembl:ENSMUST00000026662(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045137"(development of primary sexual characteristics)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR042796|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|refseq:NP_031649.2|dip:DIP-690N	-	-	-	figure legend:Supp. Fig. 4B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090("mouse-neuronal_precursor_cells(stem cells)")|taxid:10090(Mouse  Neuronal precursor cells/neural stem progenitor cells)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	rogid:nUduKr4Vds3Ta6BDINRY2hFRweU10090	intact-crc:DC0613A024CB92A1|rigid:quWEulrzdAk3ysqCg8PmBrltxA8	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8CCI5	uniprotkb:P23798	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050288|imex:IM-17309-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 4C|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	intact-crc:014CCBB33F3CE8E8|rigid:DJ9+UwMH1EphW2BfZZCc+BtNhZQ	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8CCI5	uniprotkb:Q9CQJ4	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050288|imex:IM-17309-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 4C|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	intact-crc:014CCBB33F3CE8E8|rigid:DJ9+UwMH1EphW2BfZZCc+BtNhZQ	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8VDS3	uniprotkb:Q9CQJ4	intact:EBI-1216533|ensembl:ENSMUSP00000105244|ensembl:ENSMUSP00000105245	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	psi-mi:cbx7_mouse(display_long)|uniprotkb:Cbx7(gene name)|psi-mi:Cbx7(display_short)|uniprotkb:D15Ertd417e(gene name synonym)	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050354|imex:IM-17309-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_659060.1|dip:DIP-38616N|ensembl:ENSMUSG00000053411(gene)|ensembl:ENSMUST00000109615(transcript)|ensembl:ENSMUST00000109616(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0048733"(sebaceous gland development)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|rcsb pdb:2KVM|rcsb pdb:4X3K|rcsb pdb:4X3S|rcsb pdb:4X3T|rcsb pdb:4X3U|rcsb pdb:5EJW	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 4B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:h3AMmuwoxd0XWUyvesZ73cswOvc10090	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	intact-crc:8BABF86F064EF978|rigid:/4ro2GWBdnUt2VdW+Il8PSlLo2Q	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8VDS3	uniprotkb:Q99NA9	intact:EBI-1216533|ensembl:ENSMUSP00000105244|ensembl:ENSMUSP00000105245	intact:EBI-1216589|ensembl:ENSMUSP00000026032	psi-mi:cbx7_mouse(display_long)|uniprotkb:Cbx7(gene name)|psi-mi:Cbx7(display_short)|uniprotkb:D15Ertd417e(gene name synonym)	psi-mi:pcgf6_mouse(display_long)|uniprotkb:Pcgf6(gene name)|psi-mi:Pcgf6(display_short)|uniprotkb:Mblr(gene name synonym)|uniprotkb:Rnf134(gene name synonym)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050354|imex:IM-17309-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_659060.1|dip:DIP-38616N|ensembl:ENSMUSG00000053411(gene)|ensembl:ENSMUST00000109615(transcript)|ensembl:ENSMUST00000109616(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0048733"(sebaceous gland development)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|rcsb pdb:2KVM|rcsb pdb:4X3K|rcsb pdb:4X3S|rcsb pdb:4X3T|rcsb pdb:4X3U|rcsb pdb:5EJW	refseq:NP_081930.1|ensembl:ENSMUSG00000025050(gene)|ensembl:ENSMUST00000026032(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q99NA9|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 4B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:h3AMmuwoxd0XWUyvesZ73cswOvc10090	rogid:mtN76GhIM+Ql+PBTvr6d5SU3VUw10090	intact-crc:8BABF86F064EF978|rigid:/4ro2GWBdnUt2VdW+Il8PSlLo2Q	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8VDS3	uniprotkb:P23798	intact:EBI-1216533|ensembl:ENSMUSP00000105244|ensembl:ENSMUSP00000105245	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	psi-mi:cbx7_mouse(display_long)|uniprotkb:Cbx7(gene name)|psi-mi:Cbx7(display_short)|uniprotkb:D15Ertd417e(gene name synonym)	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050354|imex:IM-17309-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_659060.1|dip:DIP-38616N|ensembl:ENSMUSG00000053411(gene)|ensembl:ENSMUST00000109615(transcript)|ensembl:ENSMUST00000109616(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0048733"(sebaceous gland development)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|rcsb pdb:2KVM|rcsb pdb:4X3K|rcsb pdb:4X3S|rcsb pdb:4X3T|rcsb pdb:4X3U|rcsb pdb:5EJW	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 4B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:h3AMmuwoxd0XWUyvesZ73cswOvc10090	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	intact-crc:8BABF86F064EF978|rigid:/4ro2GWBdnUt2VdW+Il8PSlLo2Q	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P23798	uniprotkb:Q8CCI5	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050178|imex:IM-17309-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 4C, Supp.Fig. 4B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	intact-crc:79C8B9B37A4D5BD1|rigid:ZG2HubGZ/FBUW8IMhh9qHtnSalc	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P23798	uniprotkb:Q8VDS3	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-1216533|ensembl:ENSMUSP00000105244|ensembl:ENSMUSP00000105245	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:cbx7_mouse(display_long)|uniprotkb:Cbx7(gene name)|psi-mi:Cbx7(display_short)|uniprotkb:D15Ertd417e(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050178|imex:IM-17309-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	refseq:NP_659060.1|dip:DIP-38616N|ensembl:ENSMUSG00000053411(gene)|ensembl:ENSMUST00000109615(transcript)|ensembl:ENSMUST00000109616(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0048733"(sebaceous gland development)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|rcsb pdb:2KVM|rcsb pdb:4X3K|rcsb pdb:4X3S|rcsb pdb:4X3T|rcsb pdb:4X3U|rcsb pdb:5EJW	-	-	-	figure legend:Fig. 4C, Supp.Fig. 4B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	rogid:h3AMmuwoxd0XWUyvesZ73cswOvc10090	intact-crc:79C8B9B37A4D5BD1|rigid:ZG2HubGZ/FBUW8IMhh9qHtnSalc	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P23798	uniprotkb:Q64028	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-927346|uniprotkb:P70359|uniprotkb:Q64307|uniprotkb:Q8BZ80	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:phc1_mouse(display_long)|uniprotkb:Phc1(gene name)|psi-mi:Phc1(display_short)|uniprotkb:Edr(gene name synonym)|uniprotkb:Edr1(gene name synonym)|uniprotkb:Rae28(gene name synonym)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:RAE-28(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050178|imex:IM-17309-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	refseq:NP_001258508.1|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750|mint:Q64028|dip:DIP-456N	-	-	-	figure legend:Fig. 4C, Supp.Fig. 4B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	rogid:z2SieJadS53WlofBWE3/RNMYPnw10090	intact-crc:79C8B9B37A4D5BD1|rigid:ZG2HubGZ/FBUW8IMhh9qHtnSalc	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P23798	uniprotkb:Q9CQJ4	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050178|imex:IM-17309-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 4C, Supp.Fig. 4B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	intact-crc:79C8B9B37A4D5BD1|rigid:ZG2HubGZ/FBUW8IMhh9qHtnSalc	false	flag tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8VDS3	uniprotkb:Q9CQJ4	intact:EBI-1216533|ensembl:ENSMUSP00000105244|ensembl:ENSMUSP00000105245	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	psi-mi:cbx7_mouse(display_long)|uniprotkb:Cbx7(gene name)|psi-mi:Cbx7(display_short)|uniprotkb:D15Ertd417e(gene name synonym)	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050213|imex:IM-17309-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_659060.1|dip:DIP-38616N|ensembl:ENSMUSG00000053411(gene)|ensembl:ENSMUST00000109615(transcript)|ensembl:ENSMUST00000109616(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0048733"(sebaceous gland development)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|rcsb pdb:2KVM|rcsb pdb:4X3K|rcsb pdb:4X3S|rcsb pdb:4X3T|rcsb pdb:4X3U|rcsb pdb:5EJW	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	figure legend:Supp Fig. 4D|comment:Complex present in both Polycomb protein EED +/+ and -/- cells.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:h3AMmuwoxd0XWUyvesZ73cswOvc10090	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	intact-crc:ABB5FD39DFD78609|rigid:NDWGy8H6f+XtKv3LEb+hYRFAqOk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8VDS3	uniprotkb:Q8CCI5	intact:EBI-1216533|ensembl:ENSMUSP00000105244|ensembl:ENSMUSP00000105245	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	psi-mi:cbx7_mouse(display_long)|uniprotkb:Cbx7(gene name)|psi-mi:Cbx7(display_short)|uniprotkb:D15Ertd417e(gene name synonym)	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050213|imex:IM-17309-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_659060.1|dip:DIP-38616N|ensembl:ENSMUSG00000053411(gene)|ensembl:ENSMUST00000109615(transcript)|ensembl:ENSMUST00000109616(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0048733"(sebaceous gland development)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|rcsb pdb:2KVM|rcsb pdb:4X3K|rcsb pdb:4X3S|rcsb pdb:4X3T|rcsb pdb:4X3U|rcsb pdb:5EJW	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	-	-	-	figure legend:Supp Fig. 4D|comment:Complex present in both Polycomb protein EED +/+ and -/- cells.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:h3AMmuwoxd0XWUyvesZ73cswOvc10090	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	intact-crc:ABB5FD39DFD78609|rigid:NDWGy8H6f+XtKv3LEb+hYRFAqOk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8VDS3	uniprotkb:P23798	intact:EBI-1216533|ensembl:ENSMUSP00000105244|ensembl:ENSMUSP00000105245	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	psi-mi:cbx7_mouse(display_long)|uniprotkb:Cbx7(gene name)|psi-mi:Cbx7(display_short)|uniprotkb:D15Ertd417e(gene name synonym)	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050201|imex:IM-17309-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_659060.1|dip:DIP-38616N|ensembl:ENSMUSG00000053411(gene)|ensembl:ENSMUST00000109615(transcript)|ensembl:ENSMUST00000109616(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0048733"(sebaceous gland development)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|rcsb pdb:2KVM|rcsb pdb:4X3K|rcsb pdb:4X3S|rcsb pdb:4X3T|rcsb pdb:4X3U|rcsb pdb:5EJW	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	-	-	-	figure legend:Supp. Fig. 4C|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:h3AMmuwoxd0XWUyvesZ73cswOvc10090	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	intact-crc:610754655E6698E4|rigid:8Nx1fQkMMrZtsD3xL9bchWnR+88	false	-	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8VDS3	uniprotkb:Q9CQJ4	intact:EBI-1216533|ensembl:ENSMUSP00000105244|ensembl:ENSMUSP00000105245	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	psi-mi:cbx7_mouse(display_long)|uniprotkb:Cbx7(gene name)|psi-mi:Cbx7(display_short)|uniprotkb:D15Ertd417e(gene name synonym)	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050201|imex:IM-17309-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_659060.1|dip:DIP-38616N|ensembl:ENSMUSG00000053411(gene)|ensembl:ENSMUST00000109615(transcript)|ensembl:ENSMUST00000109616(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0048733"(sebaceous gland development)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|rcsb pdb:2KVM|rcsb pdb:4X3K|rcsb pdb:4X3S|rcsb pdb:4X3T|rcsb pdb:4X3U|rcsb pdb:5EJW	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	figure legend:Supp. Fig. 4C|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:h3AMmuwoxd0XWUyvesZ73cswOvc10090	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	intact-crc:610754655E6698E4|rigid:8Nx1fQkMMrZtsD3xL9bchWnR+88	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8VDS3	uniprotkb:Q8CCI5	intact:EBI-1216533|ensembl:ENSMUSP00000105244|ensembl:ENSMUSP00000105245	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	psi-mi:cbx7_mouse(display_long)|uniprotkb:Cbx7(gene name)|psi-mi:Cbx7(display_short)|uniprotkb:D15Ertd417e(gene name synonym)	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050201|imex:IM-17309-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_659060.1|dip:DIP-38616N|ensembl:ENSMUSG00000053411(gene)|ensembl:ENSMUST00000109615(transcript)|ensembl:ENSMUST00000109616(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0048733"(sebaceous gland development)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|rcsb pdb:2KVM|rcsb pdb:4X3K|rcsb pdb:4X3S|rcsb pdb:4X3T|rcsb pdb:4X3U|rcsb pdb:5EJW	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	-	-	-	figure legend:Supp. Fig. 4C|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:h3AMmuwoxd0XWUyvesZ73cswOvc10090	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	intact-crc:610754655E6698E4|rigid:8Nx1fQkMMrZtsD3xL9bchWnR+88	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8CCI5	uniprotkb:P23798	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050392|imex:IM-17309-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 5A, Supp. Fig. 5A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	intact-crc:D2910B942FA505DE|rigid:DJ9+UwMH1EphW2BfZZCc+BtNhZQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8CCI5	uniprotkb:Q9CQJ4	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050392|imex:IM-17309-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 5A, Supp. Fig. 5A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	intact-crc:D2910B942FA505DE|rigid:DJ9+UwMH1EphW2BfZZCc+BtNhZQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CQJ4	uniprotkb:Q64028	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	intact:EBI-927346|uniprotkb:P70359|uniprotkb:Q64307|uniprotkb:Q8BZ80	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:phc1_mouse(display_long)|uniprotkb:Phc1(gene name)|psi-mi:Phc1(display_short)|uniprotkb:Edr(gene name synonym)|uniprotkb:Edr1(gene name synonym)|uniprotkb:Rae28(gene name synonym)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:RAE-28(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050396|imex:IM-17309-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	refseq:NP_001258508.1|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750|mint:Q64028|dip:DIP-456N	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 5A, Supp Fig. 5A|comment:Interaction occurs in EED +/+ and -/- cells.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	rogid:z2SieJadS53WlofBWE3/RNMYPnw10090	intact-crc:A52D70B698E1D966|rigid:ZG2HubGZ/FBUW8IMhh9qHtnSalc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CQJ4	uniprotkb:P23798	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050396|imex:IM-17309-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 5A, Supp Fig. 5A|comment:Interaction occurs in EED +/+ and -/- cells.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	intact-crc:A52D70B698E1D966|rigid:ZG2HubGZ/FBUW8IMhh9qHtnSalc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CQJ4	uniprotkb:Q8VDS3	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	intact:EBI-1216533|ensembl:ENSMUSP00000105244|ensembl:ENSMUSP00000105245	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:cbx7_mouse(display_long)|uniprotkb:Cbx7(gene name)|psi-mi:Cbx7(display_short)|uniprotkb:D15Ertd417e(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050396|imex:IM-17309-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	refseq:NP_659060.1|dip:DIP-38616N|ensembl:ENSMUSG00000053411(gene)|ensembl:ENSMUST00000109615(transcript)|ensembl:ENSMUST00000109616(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0048733"(sebaceous gland development)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|rcsb pdb:2KVM|rcsb pdb:4X3K|rcsb pdb:4X3S|rcsb pdb:4X3T|rcsb pdb:4X3U|rcsb pdb:5EJW	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 5A, Supp Fig. 5A|comment:Interaction occurs in EED +/+ and -/- cells.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	rogid:h3AMmuwoxd0XWUyvesZ73cswOvc10090	intact-crc:A52D70B698E1D966|rigid:ZG2HubGZ/FBUW8IMhh9qHtnSalc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CQJ4	uniprotkb:Q8CCI5	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050396|imex:IM-17309-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 5A, Supp Fig. 5A|comment:Interaction occurs in EED +/+ and -/- cells.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	intact-crc:A52D70B698E1D966|rigid:ZG2HubGZ/FBUW8IMhh9qHtnSalc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P23798	uniprotkb:Q8VDS3	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-1216533|ensembl:ENSMUSP00000105244|ensembl:ENSMUSP00000105245	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:cbx7_mouse(display_long)|uniprotkb:Cbx7(gene name)|psi-mi:Cbx7(display_short)|uniprotkb:D15Ertd417e(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050416|imex:IM-17309-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	refseq:NP_659060.1|dip:DIP-38616N|ensembl:ENSMUSG00000053411(gene)|ensembl:ENSMUST00000109615(transcript)|ensembl:ENSMUST00000109616(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0048733"(sebaceous gland development)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|rcsb pdb:2KVM|rcsb pdb:4X3K|rcsb pdb:4X3S|rcsb pdb:4X3T|rcsb pdb:4X3U|rcsb pdb:5EJW	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 5A, Supp. Fig. 5A|comment:Interactions were observed in EED +/+ and -/- cells.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	rogid:h3AMmuwoxd0XWUyvesZ73cswOvc10090	intact-crc:7077BED103AF6632|rigid:8Nx1fQkMMrZtsD3xL9bchWnR+88	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P23798	uniprotkb:Q8CCI5	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050416|imex:IM-17309-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 5A, Supp. Fig. 5A|comment:Interactions were observed in EED +/+ and -/- cells.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	intact-crc:7077BED103AF6632|rigid:8Nx1fQkMMrZtsD3xL9bchWnR+88	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P23798	uniprotkb:Q9CQJ4	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050416|imex:IM-17309-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 5A, Supp. Fig. 5A|comment:Interactions were observed in EED +/+ and -/- cells.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	intact-crc:7077BED103AF6632|rigid:8Nx1fQkMMrZtsD3xL9bchWnR+88	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8VDS3	uniprotkb:P23798	intact:EBI-1216533|ensembl:ENSMUSP00000105244|ensembl:ENSMUSP00000105245	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	psi-mi:cbx7_mouse(display_long)|uniprotkb:Cbx7(gene name)|psi-mi:Cbx7(display_short)|uniprotkb:D15Ertd417e(gene name synonym)	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050394|imex:IM-17309-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_659060.1|dip:DIP-38616N|ensembl:ENSMUSG00000053411(gene)|ensembl:ENSMUST00000109615(transcript)|ensembl:ENSMUST00000109616(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0048733"(sebaceous gland development)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|rcsb pdb:2KVM|rcsb pdb:4X3K|rcsb pdb:4X3S|rcsb pdb:4X3T|rcsb pdb:4X3U|rcsb pdb:5EJW	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 5A, Supp Fig. 5A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:h3AMmuwoxd0XWUyvesZ73cswOvc10090	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	intact-crc:0FE0E1769DE00DA3|rigid:XGVdk+5m5kDByrXTTjUwPfJao/s	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8VDS3	uniprotkb:Q9CQJ4	intact:EBI-1216533|ensembl:ENSMUSP00000105244|ensembl:ENSMUSP00000105245	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	psi-mi:cbx7_mouse(display_long)|uniprotkb:Cbx7(gene name)|psi-mi:Cbx7(display_short)|uniprotkb:D15Ertd417e(gene name synonym)	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050394|imex:IM-17309-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_659060.1|dip:DIP-38616N|ensembl:ENSMUSG00000053411(gene)|ensembl:ENSMUST00000109615(transcript)|ensembl:ENSMUST00000109616(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0048733"(sebaceous gland development)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|rcsb pdb:2KVM|rcsb pdb:4X3K|rcsb pdb:4X3S|rcsb pdb:4X3T|rcsb pdb:4X3U|rcsb pdb:5EJW	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 5A, Supp Fig. 5A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:h3AMmuwoxd0XWUyvesZ73cswOvc10090	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	intact-crc:0FE0E1769DE00DA3|rigid:XGVdk+5m5kDByrXTTjUwPfJao/s	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8VDS3	uniprotkb:Q64028	intact:EBI-1216533|ensembl:ENSMUSP00000105244|ensembl:ENSMUSP00000105245	intact:EBI-927346|uniprotkb:P70359|uniprotkb:Q64307|uniprotkb:Q8BZ80	psi-mi:cbx7_mouse(display_long)|uniprotkb:Cbx7(gene name)|psi-mi:Cbx7(display_short)|uniprotkb:D15Ertd417e(gene name synonym)	psi-mi:phc1_mouse(display_long)|uniprotkb:Phc1(gene name)|psi-mi:Phc1(display_short)|uniprotkb:Edr(gene name synonym)|uniprotkb:Edr1(gene name synonym)|uniprotkb:Rae28(gene name synonym)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:RAE-28(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050394|imex:IM-17309-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_659060.1|dip:DIP-38616N|ensembl:ENSMUSG00000053411(gene)|ensembl:ENSMUST00000109615(transcript)|ensembl:ENSMUST00000109616(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0048733"(sebaceous gland development)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|rcsb pdb:2KVM|rcsb pdb:4X3K|rcsb pdb:4X3S|rcsb pdb:4X3T|rcsb pdb:4X3U|rcsb pdb:5EJW	refseq:NP_001258508.1|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750|mint:Q64028|dip:DIP-456N	go:"GO:0005634"(nucleus)	-	-	figure legend:Fig. 5A, Supp Fig. 5A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:h3AMmuwoxd0XWUyvesZ73cswOvc10090	rogid:z2SieJadS53WlofBWE3/RNMYPnw10090	intact-crc:0FE0E1769DE00DA3|rigid:XGVdk+5m5kDByrXTTjUwPfJao/s	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CQJ4	uniprotkb:Q8VDS3	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	intact:EBI-1216533|ensembl:ENSMUSP00000105244|ensembl:ENSMUSP00000105245	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:cbx7_mouse(display_long)|uniprotkb:Cbx7(gene name)|psi-mi:Cbx7(display_short)|uniprotkb:D15Ertd417e(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6051691|imex:IM-17309-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	refseq:NP_659060.1|dip:DIP-38616N|ensembl:ENSMUSG00000053411(gene)|ensembl:ENSMUST00000109615(transcript)|ensembl:ENSMUST00000109616(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0048733"(sebaceous gland development)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|rcsb pdb:2KVM|rcsb pdb:4X3K|rcsb pdb:4X3S|rcsb pdb:4X3T|rcsb pdb:4X3U|rcsb pdb:5EJW	go:"GO:0005634"(nucleus)	-	-	figure legend:Supp Fig. 5B|comment:Interaction occurs in EED +/+ and -/- cells.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-fibroblast)|taxid:10090(Mus musculus)	-	2012/03/28	2014/10/16	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	rogid:h3AMmuwoxd0XWUyvesZ73cswOvc10090	intact-crc:F84A90D0FECBF468|rigid:8Nx1fQkMMrZtsD3xL9bchWnR+88	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CQJ4	uniprotkb:P23798	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6051691|imex:IM-17309-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	go:"GO:0005634"(nucleus)	-	-	figure legend:Supp Fig. 5B|comment:Interaction occurs in EED +/+ and -/- cells.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-fibroblast)|taxid:10090(Mus musculus)	-	2012/03/28	2014/10/16	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	intact-crc:F84A90D0FECBF468|rigid:8Nx1fQkMMrZtsD3xL9bchWnR+88	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CQJ4	uniprotkb:Q8CCI5	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6051691|imex:IM-17309-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	go:"GO:0005634"(nucleus)	-	-	figure legend:Supp Fig. 5B|comment:Interaction occurs in EED +/+ and -/- cells.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-fibroblast)|taxid:10090(Mus musculus)	-	2012/03/28	2014/10/16	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	intact-crc:F84A90D0FECBF468|rigid:8Nx1fQkMMrZtsD3xL9bchWnR+88	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8CCI5	uniprotkb:P23798	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6051718|imex:IM-17309-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	go:"GO:0005634"(nucleus)	-	-	figure legend:Supp Fig. 5B|comment:Interaction occurs in EED +/+ and -/- cells.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-fibroblast)|taxid:10090(Mus musculus)	-	2012/03/28	2014/10/16	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	intact-crc:A92C1B0D6CEB9948|rigid:DJ9+UwMH1EphW2BfZZCc+BtNhZQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8CCI5	uniprotkb:Q9CQJ4	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6051718|imex:IM-17309-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	go:"GO:0005634"(nucleus)	-	-	figure legend:Supp Fig. 5B|comment:Interaction occurs in EED +/+ and -/- cells.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-fibroblast)|taxid:10090(Mus musculus)	-	2012/03/28	2014/10/16	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	intact-crc:A92C1B0D6CEB9948|rigid:DJ9+UwMH1EphW2BfZZCc+BtNhZQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8VDS3	uniprotkb:Q64028	intact:EBI-1216533|ensembl:ENSMUSP00000105244|ensembl:ENSMUSP00000105245	intact:EBI-927346|uniprotkb:P70359|uniprotkb:Q64307|uniprotkb:Q8BZ80	psi-mi:cbx7_mouse(display_long)|uniprotkb:Cbx7(gene name)|psi-mi:Cbx7(display_short)|uniprotkb:D15Ertd417e(gene name synonym)	psi-mi:phc1_mouse(display_long)|uniprotkb:Phc1(gene name)|psi-mi:Phc1(display_short)|uniprotkb:Edr(gene name synonym)|uniprotkb:Edr1(gene name synonym)|uniprotkb:Rae28(gene name synonym)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:RAE-28(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050244|imex:IM-17309-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_659060.1|dip:DIP-38616N|ensembl:ENSMUSG00000053411(gene)|ensembl:ENSMUST00000109615(transcript)|ensembl:ENSMUST00000109616(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0048733"(sebaceous gland development)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|rcsb pdb:2KVM|rcsb pdb:4X3K|rcsb pdb:4X3S|rcsb pdb:4X3T|rcsb pdb:4X3U|rcsb pdb:5EJW	refseq:NP_001258508.1|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750|mint:Q64028|dip:DIP-456N	-	-	-	figure legend:Fig. 4B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:h3AMmuwoxd0XWUyvesZ73cswOvc10090	rogid:z2SieJadS53WlofBWE3/RNMYPnw10090	intact-crc:D1DF195BF40C539F|rigid:XGVdk+5m5kDByrXTTjUwPfJao/s	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8VDS3	uniprotkb:P23798	intact:EBI-1216533|ensembl:ENSMUSP00000105244|ensembl:ENSMUSP00000105245	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	psi-mi:cbx7_mouse(display_long)|uniprotkb:Cbx7(gene name)|psi-mi:Cbx7(display_short)|uniprotkb:D15Ertd417e(gene name synonym)	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050244|imex:IM-17309-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_659060.1|dip:DIP-38616N|ensembl:ENSMUSG00000053411(gene)|ensembl:ENSMUST00000109615(transcript)|ensembl:ENSMUST00000109616(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0048733"(sebaceous gland development)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|rcsb pdb:2KVM|rcsb pdb:4X3K|rcsb pdb:4X3S|rcsb pdb:4X3T|rcsb pdb:4X3U|rcsb pdb:5EJW	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 4B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:h3AMmuwoxd0XWUyvesZ73cswOvc10090	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	intact-crc:D1DF195BF40C539F|rigid:XGVdk+5m5kDByrXTTjUwPfJao/s	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8VDS3	uniprotkb:Q9CQJ4	intact:EBI-1216533|ensembl:ENSMUSP00000105244|ensembl:ENSMUSP00000105245	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	psi-mi:cbx7_mouse(display_long)|uniprotkb:Cbx7(gene name)|psi-mi:Cbx7(display_short)|uniprotkb:D15Ertd417e(gene name synonym)	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050244|imex:IM-17309-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_659060.1|dip:DIP-38616N|ensembl:ENSMUSG00000053411(gene)|ensembl:ENSMUST00000109615(transcript)|ensembl:ENSMUST00000109616(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0048733"(sebaceous gland development)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|rcsb pdb:2KVM|rcsb pdb:4X3K|rcsb pdb:4X3S|rcsb pdb:4X3T|rcsb pdb:4X3U|rcsb pdb:5EJW	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 4B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:h3AMmuwoxd0XWUyvesZ73cswOvc10090	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	intact-crc:D1DF195BF40C539F|rigid:XGVdk+5m5kDByrXTTjUwPfJao/s	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8CCI5	uniprotkb:Q8R023	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	intact:EBI-1216526|ensembl:ENSMUSP00000130614	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:pcgf1_mouse(display_long)|uniprotkb:Pcgf1(gene name)|psi-mi:Pcgf1(display_short)|uniprotkb:Nspc1(gene name synonym)|uniprotkb:Rnf68(gene name synonym)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050219|imex:IM-17309-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	refseq:NP_932109.1|ensembl:ENSMUSG00000069678(gene)|ensembl:ENSMUST00000165164(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443	-	-	-	figure legend:Fig. 4B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	rogid:pypap3CY0KPv0+g+SId2JkRTIsc10090	intact-crc:C2298CD906596317|rigid:ZSidpIXqw2mCzRW1KDKfS4manDo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8CCI5	uniprotkb:P23798	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050219|imex:IM-17309-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 4B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	intact-crc:C2298CD906596317|rigid:ZSidpIXqw2mCzRW1KDKfS4manDo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8CCI5	uniprotkb:O35730	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	intact:EBI-929310|ensembl:ENSMUSP00000025183|uniprotkb:Q3U242|uniprotkb:Q3U333|uniprotkb:Q4FK33|uniprotkb:Q63ZX8|uniprotkb:Q921Z8	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:ring1_mouse(display_long)|uniprotkb:Ring1(gene name)|psi-mi:Ring1(display_short)|uniprotkb:Ring1A(gene name synonym)|uniprotkb:Rnf1(gene name synonym)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:Transcription repressor Ring1A(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050219|imex:IM-17309-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	ensembl:ENSMUSG00000024325(gene)|ensembl:ENSMUST00000025183(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|refseq:NP_033092.3|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|interpro:IPR043540|mint:O35730|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 4B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	rogid:QwNPWozHIOz6ecIMradUC2NqbJE10090	intact-crc:C2298CD906596317|rigid:ZSidpIXqw2mCzRW1KDKfS4manDo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8CCI5	uniprotkb:Q9CQJ4	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050219|imex:IM-17309-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 4B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	intact-crc:C2298CD906596317|rigid:ZSidpIXqw2mCzRW1KDKfS4manDo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q8CCI5	uniprotkb:Q99NA9	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	intact:EBI-1216589|ensembl:ENSMUSP00000026032	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:pcgf6_mouse(display_long)|uniprotkb:Pcgf6(gene name)|psi-mi:Pcgf6(display_short)|uniprotkb:Mblr(gene name synonym)|uniprotkb:Rnf134(gene name synonym)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050219|imex:IM-17309-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	refseq:NP_081930.1|ensembl:ENSMUSG00000025050(gene)|ensembl:ENSMUST00000026032(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q99NA9|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 4B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	rogid:mtN76GhIM+Ql+PBTvr6d5SU3VUw10090	intact-crc:C2298CD906596317|rigid:ZSidpIXqw2mCzRW1KDKfS4manDo	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P23798	uniprotkb:Q9QXV1	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-1216641|ensembl:ENSMUSP00000026663	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:cbx8_mouse(display_long)|uniprotkb:Cbx8(gene name)|psi-mi:Cbx8(display_short)|uniprotkb:Pc3(gene name synonym)|uniprotkb:Polycomb 3 homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050130|imex:IM-17309-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	refseq:NP_038954.1|ensembl:ENSMUSG00000025578(gene)|ensembl:ENSMUST00000026663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|rcsb pdb:2DNV|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724	-	-	-	figure legend:Fig. 4B, Supp. Fig. 4A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	rogid:cLpux9+wXJIOUI0M01emXGUVM6c10090	intact-crc:8C871CE426F253C9|rigid:2Lem3/j0tR4OBfQtqHeOurFH6uc	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P23798	uniprotkb:Q8VDS3	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-1216533|ensembl:ENSMUSP00000105244|ensembl:ENSMUSP00000105245	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:cbx7_mouse(display_long)|uniprotkb:Cbx7(gene name)|psi-mi:Cbx7(display_short)|uniprotkb:D15Ertd417e(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050130|imex:IM-17309-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	refseq:NP_659060.1|dip:DIP-38616N|ensembl:ENSMUSG00000053411(gene)|ensembl:ENSMUST00000109615(transcript)|ensembl:ENSMUST00000109616(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0048733"(sebaceous gland development)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|rcsb pdb:2KVM|rcsb pdb:4X3K|rcsb pdb:4X3S|rcsb pdb:4X3T|rcsb pdb:4X3U|rcsb pdb:5EJW	-	-	-	figure legend:Fig. 4B, Supp. Fig. 4A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	rogid:h3AMmuwoxd0XWUyvesZ73cswOvc10090	intact-crc:8C871CE426F253C9|rigid:2Lem3/j0tR4OBfQtqHeOurFH6uc	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P23798	uniprotkb:Q64028	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-927346|uniprotkb:P70359|uniprotkb:Q64307|uniprotkb:Q8BZ80	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:phc1_mouse(display_long)|uniprotkb:Phc1(gene name)|psi-mi:Phc1(display_short)|uniprotkb:Edr(gene name synonym)|uniprotkb:Edr1(gene name synonym)|uniprotkb:Rae28(gene name synonym)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:RAE-28(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050130|imex:IM-17309-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	refseq:NP_001258508.1|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750|mint:Q64028|dip:DIP-456N	-	-	-	figure legend:Fig. 4B, Supp. Fig. 4A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	rogid:z2SieJadS53WlofBWE3/RNMYPnw10090	intact-crc:8C871CE426F253C9|rigid:2Lem3/j0tR4OBfQtqHeOurFH6uc	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P23798	uniprotkb:Q8CHP6	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-1216510|uniprotkb:A2RTJ9|uniprotkb:Q3TLV5|ensembl:ENSMUSP00000114916|ensembl:ENSMUSP00000130142	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:phc3_mouse(display_long)|uniprotkb:Phc3(gene name)|psi-mi:Phc3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050130|imex:IM-17309-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	refseq:NP_001159426.1|refseq:NP_700470.2|ensembl:ENSMUSG00000037652(gene)|ensembl:ENSMUST00000129817(transcript)|ensembl:ENSMUST00000168645(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8CHP6|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 4B, Supp. Fig. 4A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	rogid:Rzm3ZzbVX9nIMC2Jah3g4/0P12410090	intact-crc:8C871CE426F253C9|rigid:2Lem3/j0tR4OBfQtqHeOurFH6uc	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P23798	uniprotkb:Q9CQJ4	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-927321|uniprotkb:O35699|uniprotkb:O35729|uniprotkb:Q4FJV5|uniprotkb:Q8C1X8|ensembl:ENSMUSP00000075476|ensembl:ENSMUSP00000140896	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:ring2_mouse(display_long)|uniprotkb:Rnf2(gene name)|psi-mi:Rnf2(display_short)|uniprotkb:DinG(gene name synonym)|uniprotkb:Ring1b(gene name synonym)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050130|imex:IM-17309-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	refseq:NP_035407.1|dip:DIP-36109N|ensembl:ENSMUSG00000026484(gene)|ensembl:ENSMUST00000076110(transcript)|ensembl:ENSMUST00000187048(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q9CQJ4|rcsb pdb:2CKL|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 4B, Supp. Fig. 4A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	rogid:xyEv6lhWHdmO1fLEas7lRd3wbco10090	intact-crc:8C871CE426F253C9|rigid:2Lem3/j0tR4OBfQtqHeOurFH6uc	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P23798	uniprotkb:O35730	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-929310|ensembl:ENSMUSP00000025183|uniprotkb:Q3U242|uniprotkb:Q3U333|uniprotkb:Q4FK33|uniprotkb:Q63ZX8|uniprotkb:Q921Z8	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:ring1_mouse(display_long)|uniprotkb:Ring1(gene name)|psi-mi:Ring1(display_short)|uniprotkb:Ring1A(gene name synonym)|uniprotkb:Rnf1(gene name synonym)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:Transcription repressor Ring1A(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050130|imex:IM-17309-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	ensembl:ENSMUSG00000024325(gene)|ensembl:ENSMUST00000025183(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|refseq:NP_033092.3|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|interpro:IPR043540|mint:O35730|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 4B, Supp. Fig. 4A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	rogid:QwNPWozHIOz6ecIMradUC2NqbJE10090	intact-crc:8C871CE426F253C9|rigid:2Lem3/j0tR4OBfQtqHeOurFH6uc	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P23798	uniprotkb:Q8CCI5	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-929290|uniprotkb:Q9WVK2|uniprotkb:B2RRB6|ensembl:ENSMUSP00000098677	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:rybp_mouse(display_long)|uniprotkb:Rybp(gene name)|psi-mi:Rybp(display_short)|uniprotkb:Dedaf(gene name synonym)|uniprotkb:Death effector domain-associated factor(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050130|imex:IM-17309-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	refseq:NP_062717.2|ensembl:ENSMUSG00000072872(gene)|ensembl:ENSMUST00000101118(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8CCI5|reactome:R-MMU-8939243|reactome:R-MMU-8953750	-	-	-	figure legend:Fig. 4B, Supp. Fig. 4A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	rogid:6BAe40LmdbvRNKWeg5yGRcHgGRY10090	intact-crc:8C871CE426F253C9|rigid:2Lem3/j0tR4OBfQtqHeOurFH6uc	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P23798	uniprotkb:Q9QWH1	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-642357|uniprotkb:O88463|uniprotkb:Q8K5D9|uniprotkb:B1AS98|uniprotkb:B1ASA4|ensembl:ENSMUSP00000030588|ensembl:ENSMUSP00000101690	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:phc2_mouse(display_long)|uniprotkb:p36(gene name synonym)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:Phc2(gene name)|psi-mi:Phc2(display_short)|uniprotkb:Edr2(gene name synonym)|uniprotkb:Ph2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050130|imex:IM-17309-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	refseq:NP_001182012.1|refseq:NP_001182059.1|refseq:NP_061244.1|refseq:XP_006503300.1|refseq:XP_006503301.1|ensembl:ENSMUSG00000028796(gene)|ensembl:ENSMUST00000030588(transcript)|ensembl:ENSMUST00000106080(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q9QWH1|rcsb pdb:2NA1|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|refseq:XP_017175809.1	-	-	-	figure legend:Fig. 4B, Supp. Fig. 4A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	rogid:nNgSS7uHUP3sCDlztQJqi2zl2EU10090	intact-crc:8C871CE426F253C9|rigid:2Lem3/j0tR4OBfQtqHeOurFH6uc	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P23798	uniprotkb:P30658	intact:EBI-926857|ensembl:ENSMUSP00000018681|ensembl:ENSMUSP00000099437|ensembl:ENSMUSP00000126967|ensembl:ENSMUSP00000137517	intact:EBI-360174|uniprotkb:O35731|uniprotkb:A2ABG2|ensembl:ENSMUSP00000026662|uniprotkb:Q8CIA0	psi-mi:pcgf2_mouse(display_long)|uniprotkb:Pcgf2(gene name)|psi-mi:Pcgf2(display_short)|uniprotkb:Mel18(gene name synonym)|uniprotkb:Mel-18(gene name synonym)|uniprotkb:Rnf110(gene name synonym)|uniprotkb:Zfp144(gene name synonym)|uniprotkb:Znf144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:Melanoma nuclear protein 18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym)	psi-mi:cbx2_mouse(display_long)|uniprotkb:Cbx2(gene name)|psi-mi:Cbx2(display_short)|uniprotkb:M33(gene name synonym)|uniprotkb:Modifier 3 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tavares et al. (2012)	imex:IM-17309|pubmed:22325148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6050130|imex:IM-17309-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011247274.1|refseq:XP_011247275.1|refseq:XP_011247277.1|refseq:NP_001156779.1|refseq:NP_001156780.1|refseq:NP_033571.1|refseq:XP_017169992.1|dip:DIP-37645N|ensembl:ENSMUSG00000018537(gene)|ensembl:ENSMUST00000018681(transcript)|ensembl:ENSMUST00000103148(transcript)|ensembl:ENSMUST00000169807(transcript)|ensembl:ENSMUST00000179765(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8953750	ensembl:ENSMUSG00000025577(gene)|ensembl:ENSMUST00000026662(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045137"(development of primary sexual characteristics)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR042796|reactome:R-MMU-2559580|reactome:R-MMU-3108214|reactome:R-MMU-3899300|reactome:R-MMU-4551638|reactome:R-MMU-4570464|reactome:R-MMU-8939243|reactome:R-MMU-8943724|refseq:NP_031649.2|dip:DIP-690N	-	-	-	figure legend:Fig. 4B, Supp. Fig. 4A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-embryonic_stem cell)|taxid:10090(Mus musculus embryonic stem cell)	-	2012/03/28	2014/10/16	rogid:BHDGzWbi1oVLvmehDQ9Wp2x9ZVQ10090	rogid:nUduKr4Vds3Ta6BDINRY2hFRweU10090	intact-crc:8C871CE426F253C9|rigid:2Lem3/j0tR4OBfQtqHeOurFH6uc	false	flag tag:?-?	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)