#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P03165	uniprotkb:P31750	intact:EBI-7683985|intact:MINT-8306163	intact:EBI-298707|ensembl:ENSMUSP00000001780|uniprotkb:Q62274|uniprotkb:Q6GSA6	psi-mi:x_hbvd3(display_long)|uniprotkb:X(gene name)|psi-mi:X(display_short)|uniprotkb:HBx(gene name synonym)|uniprotkb:Peptide X(gene name synonym)|uniprotkb:pX(gene name synonym)	psi-mi:akt1_mouse(display_long)|uniprotkb:Akt1(gene name)|psi-mi:Akt1(display_short)|uniprotkb:Akt(gene name synonym)|uniprotkb:Rac(gene name synonym)|uniprotkb:RAC-PK-alpha(gene name synonym)|uniprotkb:AKT1 kinase(gene name synonym)|uniprotkb:Proto-oncogene c-Akt(gene name synonym)|uniprotkb:Protein kinase B(gene name synonym)|uniprotkb:Thymoma viral proto-oncogene(gene name synonym)|uniprotkb:Protein kinase B alpha(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Khattar et al. (2012)	pubmed:22309289|mint:MINT-8305662|doi:10.1111/j.1742-4658.2012.08514|mint:fj-11-0972.r1	taxid:490133(hbvd3)|taxid:490133("Hepatitis B virus genotype D subtype ayw (isolate France/Tiollais/1979)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7683978|mint:MINT-8306159	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019079"(viral genome replication)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039592"(suppression by virus of G2/M transition of host mitotic cell cycle)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000236(Transactivation protein X)|mint:MINT-8306185(identity)	go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0099104"(potassium channel activator activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:0140052"(cellular response to oxidised low-density lipoprotein particle stimulus)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034676|interpro:IPR039026|interpro:IPR039027|mint:P31750|reactome:R-MMU-1257604|reactome:R-MMU-1358803|reactome:R-MMU-1474151|reactome:R-MMU-165159|reactome:R-MMU-198323|reactome:R-MMU-198693|reactome:R-MMU-199418|reactome:R-MMU-203615|reactome:R-MMU-211163|reactome:R-MMU-354192|reactome:R-MMU-3769402|reactome:R-MMU-389357|reactome:R-MMU-389513|reactome:R-MMU-392451|reactome:R-MMU-450385|reactome:R-MMU-450604|reactome:R-MMU-5218920|reactome:R-MMU-5628897|reactome:R-MMU-6804757|reactome:R-MMU-6804758|reactome:R-MMU-6804759|reactome:R-MMU-6811558|reactome:R-MMU-69202|reactome:R-MMU-69656|reactome:R-MMU-8849469|reactome:R-MMU-8876198|reactome:R-MMU-8948751|reactome:R-MMU-9009391|reactome:R-MMU-9604323|reactome:R-MMU-9607240|reactome:R-MMU-9614399|reactome:R-MMU-9634638|ensembl:ENSMUSG00000001729(gene)|ensembl:ENSMUST00000001780(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0002931"(response to ischemia)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007281"(germ cell development)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0009725"(response to hormone)|go:"GO:0010033"(response to organic substance)|go:"GO:0010467"(gene expression)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010748"(negative regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030030"(cell projection organization)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0031982"(vesicle)|go:"GO:0031999"(negative regulation of fatty acid beta-oxidation)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032094"(response to food)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035655"(interleukin-18-mediated signaling pathway)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060709"(glycogen cell differentiation involved in embryonic placenta development)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0070141"(response to UV-A)|go:"GO:0070848"(response to growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|refseq:NP_001159366.1|refseq:NP_033782.1|refseq:XP_006515478.1|refseq:NP_001318036.1|dip:DIP-736N|mint:MINT-8306161(identity)	-	comment:mint	-	figure legend:f1b|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/01/27	2014/10/16	rogid:27z7IV7fbDf9xLBdQCG9J+c136I490133	rogid:qZx+MZ1X4i0lL1kvsVCsxJONKQ410090	intact-crc:AEB7CCCB06B38F70|rigid:xt5O9PfJUop2yThV9c9bMszhZXo	false	phosphorylated residue:31-31(MINT-8306189)|his tag:?-?(MINT-8306234)	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P03165	uniprotkb:P31750	intact:EBI-7683985|intact:MINT-8306163	intact:EBI-298707|ensembl:ENSMUSP00000001780|uniprotkb:Q62274|uniprotkb:Q6GSA6	psi-mi:x_hbvd3(display_long)|uniprotkb:X(gene name)|psi-mi:X(display_short)|uniprotkb:HBx(gene name synonym)|uniprotkb:Peptide X(gene name synonym)|uniprotkb:pX(gene name synonym)	psi-mi:akt1_mouse(display_long)|uniprotkb:Akt1(gene name)|psi-mi:Akt1(display_short)|uniprotkb:Akt(gene name synonym)|uniprotkb:Rac(gene name synonym)|uniprotkb:RAC-PK-alpha(gene name synonym)|uniprotkb:AKT1 kinase(gene name synonym)|uniprotkb:Proto-oncogene c-Akt(gene name synonym)|uniprotkb:Protein kinase B(gene name synonym)|uniprotkb:Thymoma viral proto-oncogene(gene name synonym)|uniprotkb:Protein kinase B alpha(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Khattar et al. (2012)	pubmed:22309289|mint:MINT-8305662|doi:10.1111/j.1742-4658.2012.08514|mint:fj-11-0972.r1	taxid:490133(hbvd3)|taxid:490133("Hepatitis B virus genotype D subtype ayw (isolate France/Tiollais/1979)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7684068|mint:MINT-8306194	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019079"(viral genome replication)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039592"(suppression by virus of G2/M transition of host mitotic cell cycle)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000236(Transactivation protein X)|mint:MINT-8306198(identity)	go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0099104"(potassium channel activator activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:0140052"(cellular response to oxidised low-density lipoprotein particle stimulus)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034676|interpro:IPR039026|interpro:IPR039027|mint:P31750|reactome:R-MMU-1257604|reactome:R-MMU-1358803|reactome:R-MMU-1474151|reactome:R-MMU-165159|reactome:R-MMU-198323|reactome:R-MMU-198693|reactome:R-MMU-199418|reactome:R-MMU-203615|reactome:R-MMU-211163|reactome:R-MMU-354192|reactome:R-MMU-3769402|reactome:R-MMU-389357|reactome:R-MMU-389513|reactome:R-MMU-392451|reactome:R-MMU-450385|reactome:R-MMU-450604|reactome:R-MMU-5218920|reactome:R-MMU-5628897|reactome:R-MMU-6804757|reactome:R-MMU-6804758|reactome:R-MMU-6804759|reactome:R-MMU-6811558|reactome:R-MMU-69202|reactome:R-MMU-69656|reactome:R-MMU-8849469|reactome:R-MMU-8876198|reactome:R-MMU-8948751|reactome:R-MMU-9009391|reactome:R-MMU-9604323|reactome:R-MMU-9607240|reactome:R-MMU-9614399|reactome:R-MMU-9634638|ensembl:ENSMUSG00000001729(gene)|ensembl:ENSMUST00000001780(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0002931"(response to ischemia)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007281"(germ cell development)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0009725"(response to hormone)|go:"GO:0010033"(response to organic substance)|go:"GO:0010467"(gene expression)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010748"(negative regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030030"(cell projection organization)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0031982"(vesicle)|go:"GO:0031999"(negative regulation of fatty acid beta-oxidation)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032094"(response to food)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035655"(interleukin-18-mediated signaling pathway)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060709"(glycogen cell differentiation involved in embryonic placenta development)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0070141"(response to UV-A)|go:"GO:0070848"(response to growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|refseq:NP_001159366.1|refseq:NP_033782.1|refseq:XP_006515478.1|refseq:NP_001318036.1|dip:DIP-736N|mint:MINT-8306196(identity)	-	comment:mint	-	figure legend:f1c|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/01/27	2014/10/16	rogid:27z7IV7fbDf9xLBdQCG9J+c136I490133	rogid:qZx+MZ1X4i0lL1kvsVCsxJONKQ410090	intact-crc:012C78BFF21A7FF3|rigid:xt5O9PfJUop2yThV9c9bMszhZXo	false	glutathione s tranferase tag:?-?(MINT-8306205)|binding-associated region:25-35(MINT-8306207)	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P03165	uniprotkb:P31749	intact:EBI-7683985|intact:MINT-8306163	intact:EBI-296087|uniprotkb:Q9BWB6|ensembl:ENSP00000270202|ensembl:ENSP00000384293|ensembl:ENSP00000385326|ensembl:ENSP00000450688|ensembl:ENSP00000451166|ensembl:ENSP00000451828|ensembl:ENSP00000507879|ensembl:ENSP00000497822|uniprotkb:B2RAM5|uniprotkb:B7Z5R1	psi-mi:x_hbvd3(display_long)|uniprotkb:X(gene name)|psi-mi:X(display_short)|uniprotkb:HBx(gene name synonym)|uniprotkb:Peptide X(gene name synonym)|uniprotkb:pX(gene name synonym)	psi-mi:akt1_human(display_long)|uniprotkb:AKT1(gene name)|psi-mi:AKT1(display_short)|uniprotkb:PKB(gene name synonym)|uniprotkb:RAC(gene name synonym)|uniprotkb:RAC-PK-alpha(gene name synonym)|uniprotkb:Protein kinase B(gene name synonym)|uniprotkb:Proto-oncogene c-Akt(gene name synonym)|uniprotkb:Protein kinase B alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Khattar et al. (2012)	pubmed:22309289|mint:MINT-8305662|doi:10.1111/j.1742-4658.2012.08514|mint:fj-11-0972.r1	taxid:490133(hbvd3)|taxid:490133("Hepatitis B virus genotype D subtype ayw (isolate France/Tiollais/1979)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7684206|mint:MINT-8306213	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019079"(viral genome replication)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039592"(suppression by virus of G2/M transition of host mitotic cell cycle)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000236(Transactivation protein X)|mint:MINT-8306216(identity)	go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0009408"(response to heat)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010748"(negative regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0010761"(fibroblast migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0007568"(aging)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043276"(anoikis)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|ensembl:ENSG00000142208(gene)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0031929"(TOR signaling)|go:"GO:0031982"(vesicle)|go:"GO:0031999"(negative regulation of fatty acid beta-oxidation)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032094"(response to food)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035655"(interleukin-18-mediated signaling pathway)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|ensembl:ENST00000349310(transcript)|ensembl:ENST00000402615(transcript)|ensembl:ENST00000407796(transcript)|ensembl:ENST00000554581(transcript)|ensembl:ENST00000554848(transcript)|ensembl:ENST00000555528(transcript)|ensembl:ENST00000649815(transcript)|ensembl:ENST00000683722(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0002931"(response to ischemia)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007281"(germ cell development)|go:"GO:0005739"(mitochondrion)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060709"(glycogen cell differentiation involved in embryonic placenta development)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0070141"(response to UV-A)|go:"GO:0070848"(response to growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0098794"(postsynapse)|go:"GO:0099104"(potassium channel activator activity)|go:"GO:0100002"(negative regulation of protein kinase activity by protein phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:0140052"(cellular response to oxidised low-density lipoprotein particle stimulus)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034676|interpro:IPR039026|interpro:IPR039027|mint:P31749|rcsb pdb:1H10|rcsb pdb:1UNP|rcsb pdb:1UNQ|reactome:R-HSA-1474151|reactome:R-HSA-165159|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418|reactome:R-HSA-203615|reactome:R-HSA-211163|reactome:R-HSA-354192|reactome:R-HSA-3769402|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-450385|reactome:R-HSA-450604|reactome:R-HSA-5218920|rcsb pdb:6S9X|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-111447|reactome:R-HSA-6785807|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-1445148|reactome:R-HSA-6811558|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8849469|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9009391|rcsb pdb:1UNR|rcsb pdb:2UVM|rcsb pdb:2UZR|rcsb pdb:2UZS|rcsb pdb:3CQU|rcsb pdb:3CQW|rcsb pdb:3MV5|rcsb pdb:3MVH|rcsb pdb:3O96|rcsb pdb:3OCB|rcsb pdb:3OW4|rcsb pdb:3QKK|rcsb pdb:3QKL|rcsb pdb:3QKM|rcsb pdb:4EJN|rcsb pdb:4EKK|rcsb pdb:4EKL|rcsb pdb:4GV1|rcsb pdb:5KCV|rcsb pdb:6BUU|rcsb pdb:6CCY|rcsb pdb:6HHF|rcsb pdb:6HHG|rcsb pdb:6HHH|rcsb pdb:6HHI|rcsb pdb:6HHJ|rcsb pdb:6NPZ|rcsb pdb:6S9W|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|reactome:R-HSA-9604323|refseq:NP_001014431.1|refseq:NP_001014432.1|refseq:NP_005154.2|refseq:XP_005267458.1|dip:DIP-24269N|mint:MINT-8306215(identity)	-	comment:mint	-	figure legend:f3a|comment:mint	taxid:9606(human-hep_g2)|taxid:9606("Homo sapiens hepatocellular carcinoma (HCC) cells (p53-wt).")	-	2012/01/27	2014/10/16	rogid:27z7IV7fbDf9xLBdQCG9J+c136I490133	rogid:9bYBB1SbEBm+NM0maKOC5Bx6KlI9606	intact-crc:48963C997E0DB749|rigid:Me8OqDmhBx+gGBROR6I7EsxPEp8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P03165	uniprotkb:P31749	intact:EBI-7683985|intact:MINT-8306163	intact:EBI-296087|uniprotkb:Q9BWB6|ensembl:ENSP00000270202|ensembl:ENSP00000384293|ensembl:ENSP00000385326|ensembl:ENSP00000450688|ensembl:ENSP00000451166|ensembl:ENSP00000451828|ensembl:ENSP00000507879|ensembl:ENSP00000497822|uniprotkb:B2RAM5|uniprotkb:B7Z5R1	psi-mi:x_hbvd3(display_long)|uniprotkb:X(gene name)|psi-mi:X(display_short)|uniprotkb:HBx(gene name synonym)|uniprotkb:Peptide X(gene name synonym)|uniprotkb:pX(gene name synonym)	psi-mi:akt1_human(display_long)|uniprotkb:AKT1(gene name)|psi-mi:AKT1(display_short)|uniprotkb:PKB(gene name synonym)|uniprotkb:RAC(gene name synonym)|uniprotkb:RAC-PK-alpha(gene name synonym)|uniprotkb:Protein kinase B(gene name synonym)|uniprotkb:Proto-oncogene c-Akt(gene name synonym)|uniprotkb:Protein kinase B alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Khattar et al. (2012)	pubmed:22309289|mint:MINT-8305662|doi:10.1111/j.1742-4658.2012.08514|mint:fj-11-0972.r1	taxid:490133(hbvd3)|taxid:490133("Hepatitis B virus genotype D subtype ayw (isolate France/Tiollais/1979)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7684232|mint:MINT-8306224	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019079"(viral genome replication)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039592"(suppression by virus of G2/M transition of host mitotic cell cycle)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000236(Transactivation protein X)|mint:MINT-8306228(identity)	go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0009408"(response to heat)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010748"(negative regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0010761"(fibroblast migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0007568"(aging)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043276"(anoikis)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|ensembl:ENSG00000142208(gene)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0031929"(TOR signaling)|go:"GO:0031982"(vesicle)|go:"GO:0031999"(negative regulation of fatty acid beta-oxidation)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032094"(response to food)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035655"(interleukin-18-mediated signaling pathway)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|ensembl:ENST00000349310(transcript)|ensembl:ENST00000402615(transcript)|ensembl:ENST00000407796(transcript)|ensembl:ENST00000554581(transcript)|ensembl:ENST00000554848(transcript)|ensembl:ENST00000555528(transcript)|ensembl:ENST00000649815(transcript)|ensembl:ENST00000683722(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0002931"(response to ischemia)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007281"(germ cell development)|go:"GO:0005739"(mitochondrion)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060709"(glycogen cell differentiation involved in embryonic placenta development)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0070141"(response to UV-A)|go:"GO:0070848"(response to growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0098794"(postsynapse)|go:"GO:0099104"(potassium channel activator activity)|go:"GO:0100002"(negative regulation of protein kinase activity by protein phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:0140052"(cellular response to oxidised low-density lipoprotein particle stimulus)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034676|interpro:IPR039026|interpro:IPR039027|mint:P31749|rcsb pdb:1H10|rcsb pdb:1UNP|rcsb pdb:1UNQ|reactome:R-HSA-1474151|reactome:R-HSA-165159|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418|reactome:R-HSA-203615|reactome:R-HSA-211163|reactome:R-HSA-354192|reactome:R-HSA-3769402|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-450385|reactome:R-HSA-450604|reactome:R-HSA-5218920|rcsb pdb:6S9X|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-111447|reactome:R-HSA-6785807|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-1445148|reactome:R-HSA-6811558|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8849469|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9009391|rcsb pdb:1UNR|rcsb pdb:2UVM|rcsb pdb:2UZR|rcsb pdb:2UZS|rcsb pdb:3CQU|rcsb pdb:3CQW|rcsb pdb:3MV5|rcsb pdb:3MVH|rcsb pdb:3O96|rcsb pdb:3OCB|rcsb pdb:3OW4|rcsb pdb:3QKK|rcsb pdb:3QKL|rcsb pdb:3QKM|rcsb pdb:4EJN|rcsb pdb:4EKK|rcsb pdb:4EKL|rcsb pdb:4GV1|rcsb pdb:5KCV|rcsb pdb:6BUU|rcsb pdb:6CCY|rcsb pdb:6HHF|rcsb pdb:6HHG|rcsb pdb:6HHH|rcsb pdb:6HHI|rcsb pdb:6HHJ|rcsb pdb:6NPZ|rcsb pdb:6S9W|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|reactome:R-HSA-9604323|refseq:NP_001014431.1|refseq:NP_001014432.1|refseq:NP_005154.2|refseq:XP_005267458.1|dip:DIP-24269N|mint:MINT-8306226(identity)	-	comment:mint	-	figure legend:f3b|comment:mint	taxid:9606(human-hep_g2)|taxid:9606("Homo sapiens hepatocellular carcinoma (HCC) cells (p53-wt).")	-	2012/01/27	2014/10/16	rogid:27z7IV7fbDf9xLBdQCG9J+c136I490133	rogid:9bYBB1SbEBm+NM0maKOC5Bx6KlI9606	intact-crc:7EDB244D7F519EB5|rigid:Me8OqDmhBx+gGBROR6I7EsxPEp8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5T1C6	uniprotkb:P31749	intact:EBI-7684443|ensembl:ENSP00000357804|uniprotkb:Q96KR2|uniprotkb:B2RBX2|intact:MINT-8306269	intact:EBI-296087|uniprotkb:Q9BWB6|ensembl:ENSP00000270202|ensembl:ENSP00000384293|ensembl:ENSP00000385326|ensembl:ENSP00000450688|ensembl:ENSP00000451166|ensembl:ENSP00000451828|ensembl:ENSP00000507879|ensembl:ENSP00000497822|uniprotkb:B2RAM5|uniprotkb:B7Z5R1	psi-mi:them4_human(display_long)|uniprotkb:THEM4(gene name)|psi-mi:THEM4(display_short)|uniprotkb:CTMP(gene name synonym)|uniprotkb:Carboxyl-terminal modulator protein(gene name synonym)|uniprotkb:Thioesterase superfamily member 4(gene name synonym)	psi-mi:akt1_human(display_long)|uniprotkb:AKT1(gene name)|psi-mi:AKT1(display_short)|uniprotkb:PKB(gene name synonym)|uniprotkb:RAC(gene name synonym)|uniprotkb:RAC-PK-alpha(gene name synonym)|uniprotkb:Protein kinase B(gene name synonym)|uniprotkb:Proto-oncogene c-Akt(gene name synonym)|uniprotkb:Protein kinase B alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Khattar et al. (2012)	pubmed:22309289|mint:MINT-8305662|doi:10.1111/j.1742-4658.2012.08514|mint:fj-11-0972.r1	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7684480|mint:MINT-8306257	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000159445(gene)|ensembl:ENST00000368814(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|interpro:IPR006683(Thioesterase superfamily)|interpro:IPR029069|rcsb pdb:4AE8|rcsb pdb:4GAH|reactome:R-HSA-1257604|reactome:R-HSA-165158|reactome:R-HSA-199418|reactome:R-HSA-389357|reactome:R-HSA-5218920|reactome:R-HSA-77289|refseq:NP_444283.2|dip:DIP-60764N|mint:MINT-8306282(identity)	go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0009408"(response to heat)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010748"(negative regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0010761"(fibroblast migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0007568"(aging)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043276"(anoikis)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|ensembl:ENSG00000142208(gene)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0031929"(TOR signaling)|go:"GO:0031982"(vesicle)|go:"GO:0031999"(negative regulation of fatty acid beta-oxidation)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032094"(response to food)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035655"(interleukin-18-mediated signaling pathway)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|ensembl:ENST00000349310(transcript)|ensembl:ENST00000402615(transcript)|ensembl:ENST00000407796(transcript)|ensembl:ENST00000554581(transcript)|ensembl:ENST00000554848(transcript)|ensembl:ENST00000555528(transcript)|ensembl:ENST00000649815(transcript)|ensembl:ENST00000683722(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0002931"(response to ischemia)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007281"(germ cell development)|go:"GO:0005739"(mitochondrion)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060709"(glycogen cell differentiation involved in embryonic placenta development)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0070141"(response to UV-A)|go:"GO:0070848"(response to growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0098794"(postsynapse)|go:"GO:0099104"(potassium channel activator activity)|go:"GO:0100002"(negative regulation of protein kinase activity by protein phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:0140052"(cellular response to oxidised low-density lipoprotein particle stimulus)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034676|interpro:IPR039026|interpro:IPR039027|mint:P31749|rcsb pdb:1H10|rcsb pdb:1UNP|rcsb pdb:1UNQ|reactome:R-HSA-1474151|reactome:R-HSA-165159|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418|reactome:R-HSA-203615|reactome:R-HSA-211163|reactome:R-HSA-354192|reactome:R-HSA-3769402|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-450385|reactome:R-HSA-450604|reactome:R-HSA-5218920|rcsb pdb:6S9X|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-111447|reactome:R-HSA-6785807|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-1445148|reactome:R-HSA-6811558|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8849469|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9009391|rcsb pdb:1UNR|rcsb pdb:2UVM|rcsb pdb:2UZR|rcsb pdb:2UZS|rcsb pdb:3CQU|rcsb pdb:3CQW|rcsb pdb:3MV5|rcsb pdb:3MVH|rcsb pdb:3O96|rcsb pdb:3OCB|rcsb pdb:3OW4|rcsb pdb:3QKK|rcsb pdb:3QKL|rcsb pdb:3QKM|rcsb pdb:4EJN|rcsb pdb:4EKK|rcsb pdb:4EKL|rcsb pdb:4GV1|rcsb pdb:5KCV|rcsb pdb:6BUU|rcsb pdb:6CCY|rcsb pdb:6HHF|rcsb pdb:6HHG|rcsb pdb:6HHH|rcsb pdb:6HHI|rcsb pdb:6HHJ|rcsb pdb:6NPZ|rcsb pdb:6S9W|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|reactome:R-HSA-9604323|refseq:NP_001014431.1|refseq:NP_001014432.1|refseq:NP_005154.2|refseq:XP_005267458.1|dip:DIP-24269N|mint:MINT-8306259(identity)	-	comment:mint|comment:homomint	-	figure legend:f3c|comment:homomint|comment:mint	taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma)	-	2012/01/27	2014/10/16	rogid:wgpknFKS1Xb9JWYSXKF/ImKoGx89606	rogid:9bYBB1SbEBm+NM0maKOC5Bx6KlI9606	intact-crc:FD3F444B47E24171|rigid:2Qt7RQgktHAvCHeID8/dIaPXutI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P03165	uniprotkb:P31749	intact:EBI-7683985|intact:MINT-8306163	intact:EBI-296087|uniprotkb:Q9BWB6|ensembl:ENSP00000270202|ensembl:ENSP00000384293|ensembl:ENSP00000385326|ensembl:ENSP00000450688|ensembl:ENSP00000451166|ensembl:ENSP00000451828|ensembl:ENSP00000507879|ensembl:ENSP00000497822|uniprotkb:B2RAM5|uniprotkb:B7Z5R1	psi-mi:x_hbvd3(display_long)|uniprotkb:X(gene name)|psi-mi:X(display_short)|uniprotkb:HBx(gene name synonym)|uniprotkb:Peptide X(gene name synonym)|uniprotkb:pX(gene name synonym)	psi-mi:akt1_human(display_long)|uniprotkb:AKT1(gene name)|psi-mi:AKT1(display_short)|uniprotkb:PKB(gene name synonym)|uniprotkb:RAC(gene name synonym)|uniprotkb:RAC-PK-alpha(gene name synonym)|uniprotkb:Protein kinase B(gene name synonym)|uniprotkb:Proto-oncogene c-Akt(gene name synonym)|uniprotkb:Protein kinase B alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Khattar et al. (2012)	pubmed:22309289|mint:MINT-8305662|doi:10.1111/j.1742-4658.2012.08514|mint:fj-11-0972.r1	taxid:490133(hbvd3)|taxid:490133("Hepatitis B virus genotype D subtype ayw (isolate France/Tiollais/1979)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7684383|mint:MINT-8306240	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019079"(viral genome replication)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039592"(suppression by virus of G2/M transition of host mitotic cell cycle)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000236(Transactivation protein X)|mint:MINT-8306244(identity)	go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0009408"(response to heat)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010748"(negative regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0010761"(fibroblast migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0007568"(aging)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043276"(anoikis)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|ensembl:ENSG00000142208(gene)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0031929"(TOR signaling)|go:"GO:0031982"(vesicle)|go:"GO:0031999"(negative regulation of fatty acid beta-oxidation)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032094"(response to food)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035655"(interleukin-18-mediated signaling pathway)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|ensembl:ENST00000349310(transcript)|ensembl:ENST00000402615(transcript)|ensembl:ENST00000407796(transcript)|ensembl:ENST00000554581(transcript)|ensembl:ENST00000554848(transcript)|ensembl:ENST00000555528(transcript)|ensembl:ENST00000649815(transcript)|ensembl:ENST00000683722(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0002931"(response to ischemia)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007281"(germ cell development)|go:"GO:0005739"(mitochondrion)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060709"(glycogen cell differentiation involved in embryonic placenta development)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0070141"(response to UV-A)|go:"GO:0070848"(response to growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0098794"(postsynapse)|go:"GO:0099104"(potassium channel activator activity)|go:"GO:0100002"(negative regulation of protein kinase activity by protein phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:0140052"(cellular response to oxidised low-density lipoprotein particle stimulus)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034676|interpro:IPR039026|interpro:IPR039027|mint:P31749|rcsb pdb:1H10|rcsb pdb:1UNP|rcsb pdb:1UNQ|reactome:R-HSA-1474151|reactome:R-HSA-165159|reactome:R-HSA-198323|reactome:R-HSA-198693|reactome:R-HSA-199418|reactome:R-HSA-203615|reactome:R-HSA-211163|reactome:R-HSA-354192|reactome:R-HSA-3769402|reactome:R-HSA-389357|reactome:R-HSA-389513|reactome:R-HSA-392451|reactome:R-HSA-450385|reactome:R-HSA-450604|reactome:R-HSA-5218920|rcsb pdb:6S9X|reactome:R-HSA-5628897|reactome:R-HSA-5674400|reactome:R-HSA-111447|reactome:R-HSA-6785807|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-1257604|reactome:R-HSA-1358803|reactome:R-HSA-1445148|reactome:R-HSA-6811558|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8849469|reactome:R-HSA-8876198|reactome:R-HSA-8941332|reactome:R-HSA-8948751|reactome:R-HSA-9009391|rcsb pdb:1UNR|rcsb pdb:2UVM|rcsb pdb:2UZR|rcsb pdb:2UZS|rcsb pdb:3CQU|rcsb pdb:3CQW|rcsb pdb:3MV5|rcsb pdb:3MVH|rcsb pdb:3O96|rcsb pdb:3OCB|rcsb pdb:3OW4|rcsb pdb:3QKK|rcsb pdb:3QKL|rcsb pdb:3QKM|rcsb pdb:4EJN|rcsb pdb:4EKK|rcsb pdb:4EKL|rcsb pdb:4GV1|rcsb pdb:5KCV|rcsb pdb:6BUU|rcsb pdb:6CCY|rcsb pdb:6HHF|rcsb pdb:6HHG|rcsb pdb:6HHH|rcsb pdb:6HHI|rcsb pdb:6HHJ|rcsb pdb:6NPZ|rcsb pdb:6S9W|reactome:R-HSA-9607240|reactome:R-HSA-9614399|reactome:R-HSA-9634638|reactome:R-HSA-9604323|refseq:NP_001014431.1|refseq:NP_001014432.1|refseq:NP_005154.2|refseq:XP_005267458.1|dip:DIP-24269N|mint:MINT-8306242(identity)	-	comment:mint	-	figure legend:f3c|comment:mint	taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma)	-	2012/01/27	2014/10/16	rogid:27z7IV7fbDf9xLBdQCG9J+c136I490133	rogid:9bYBB1SbEBm+NM0maKOC5Bx6KlI9606	intact-crc:B49FB648E8175F0D|rigid:Me8OqDmhBx+gGBROR6I7EsxPEp8	false	mutation disrupting interaction:31-31(MINT-8306254)|his tag:?-?(MINT-8306251)	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P03165	uniprotkb:P27348	intact:EBI-7683985|intact:MINT-8306163	intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081|ensembl:ENSP00000371267	psi-mi:x_hbvd3(display_long)|uniprotkb:X(gene name)|psi-mi:X(display_short)|uniprotkb:HBx(gene name synonym)|uniprotkb:Peptide X(gene name synonym)|uniprotkb:pX(gene name synonym)	psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Khattar et al. (2012)	pubmed:22309289|mint:MINT-8305662|doi:10.1111/j.1742-4658.2012.08514|mint:fj-11-0972.r1	taxid:490133(hbvd3)|taxid:490133("Hepatitis B virus genotype D subtype ayw (isolate France/Tiollais/1979)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7684554|mint:MINT-8306569	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019079"(viral genome replication)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039592"(suppression by virus of G2/M transition of host mitotic cell cycle)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000236(Transactivation protein X)|mint:MINT-8306573(identity)	refseq:NP_006817.1|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|ensembl:ENSG00000134308(gene)|ensembl:ENST00000238081(transcript)|ensembl:ENST00000381844(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|dip:DIP-27584N|mint:MINT-8306571(identity)	-	comment:mint	-	figure legend:sf1b|comment:domino|comment:mint	taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma)	-	2012/01/27	2014/10/16	rogid:27z7IV7fbDf9xLBdQCG9J+c136I490133	rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606	intact-crc:42DFA869DD1D8F5C|rigid:/HeEBhc85aM3HG3xra/jcjtM9RA	false	his tag:?-?(MINT-8306574)	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P03165	uniprotkb:P16220	intact:EBI-7683985|intact:MINT-8306163	intact:EBI-711855|uniprotkb:P21934|uniprotkb:Q9UMA7|intact:EBI-28970080|ensembl:ENSP00000236995|ensembl:ENSP00000405539|uniprotkb:Q6V963	psi-mi:x_hbvd3(display_long)|uniprotkb:X(gene name)|psi-mi:X(display_short)|uniprotkb:HBx(gene name synonym)|uniprotkb:Peptide X(gene name synonym)|uniprotkb:pX(gene name synonym)	psi-mi:creb1_human(display_long)|uniprotkb:CREB1(gene name)|psi-mi:CREB1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Khattar et al. (2012)	pubmed:22309289|mint:MINT-8305662|doi:10.1111/j.1742-4658.2012.08514|mint:fj-11-0972.r1	taxid:490133(hbvd3)|taxid:490133("Hepatitis B virus genotype D subtype ayw (isolate France/Tiollais/1979)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7684526|mint:MINT-8306294	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0019079"(viral genome replication)|go:"GO:0033650"(host cell mitochondrion)|go:"GO:0039592"(suppression by virus of G2/M transition of host mitotic cell cycle)|go:"GO:0039652"(induction by virus of host NF-kappaB cascade)|go:"GO:0042025"(host cell nucleus)|interpro:IPR000236(Transactivation protein X)|mint:MINT-8306297(identity)	go:"GO:0000791"(euchromatin)|ensembl:ENSG00000118260(gene)|ensembl:ENST00000353267(transcript)|ensembl:ENST00000430624(transcript)|go:"GO:0000785"(chromatin)|ensembl:ENSP00000236995|ensembl:ENSP00000405539|ensembl:ENST00000432329|ensembl:ENSP00000387699|refseq:NP_004370.1|refseq:NP_604391.1|refseq:XP_011508947.1|dip:DIP-765N|refseq:XP_011508949.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0007613"(memory)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008361"(regulation of cell size)|go:"GO:0008542"(visual learning)|go:"GO:0010033"(response to organic substance)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0014823"(response to activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030424"(axon)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032916"(positive regulation of transforming growth factor beta3 production)|go:"GO:0033363"(secretory granule organization)|go:"GO:0033762"(response to glucagon)|go:"GO:0034670"(chemotaxis to arachidonic acid)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0055025"(positive regulation of cardiac muscle tissue development)|go:"GO:0060251"(regulation of glial cell proliferation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060509"(type I pneumocyte differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990589"(ATF4-CREB1 transcription factor complex)|go:"GO:1990763"(arrestin family protein binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001630("cAMP response element binding (CREB) protein")|interpro:IPR003102(Coactivator CBP, pKID)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029802|mint:P16220|rcsb pdb:2LXT|rcsb pdb:5ZK1|rcsb pdb:5ZKO|reactome:R-HSA-111931|reactome:R-HSA-111932|reactome:R-HSA-198693|reactome:R-HSA-199920|reactome:R-HSA-2151201|reactome:R-HSA-2197563|reactome:R-HSA-375165|reactome:R-HSA-400253|reactome:R-HSA-442720|reactome:R-HSA-442729|reactome:R-HSA-442742|reactome:R-HSA-5674400|reactome:R-HSA-881907|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9022707|reactome:R-HSA-9031628|reactome:R-HSA-9609690|reactome:R-HSA-9616222|reactome:R-HSA-9634638|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-9707616|mint:MINT-8306296(identity)	-	comment:mint	-	figure legend:f3d|comment:mint	taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma)	-	2012/01/27	2020/10/21	rogid:27z7IV7fbDf9xLBdQCG9J+c136I490133	rogid:+gDlECcpJ4ma+wfUc19mIXyACKU9606	intact-crc:60DED6865FE55444|rigid:TToRvCJgVDE5ZHVMu3EkNh+CqGk	false	his tag:?-?(MINT-8306299)	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)