#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q00560	uniprotkb:P97378	intact:EBI-3862992|intact:EBI-15596000|uniprotkb:G5E8D2|ensembl:ENSMUSP00000064205|ensembl:ENSMUSP00000138836|ensembl:ENSMUSP00000139227	intact:EBI-6253448|ensembl:ENSMUSP00000010605|uniprotkb:B9EHD9	psi-mi:il6rb_mouse(display_long)|uniprotkb:Il6st(gene name)|psi-mi:Il6st(display_short)|uniprotkb:Interleukin-6 signal transducer(gene name synonym)|uniprotkb:Membrane glycoprotein 130(gene name synonym)|uniprotkb:Oncostatin-M receptor subunit alpha(gene name synonym)	psi-mi:i12r2_mouse(display_long)|uniprotkb:Il12rb2(gene name)|psi-mi:Il12rb2(display_short)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Collison et al. (2012)	pubmed:22306691|imex:IM-18029	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-6253476|imex:IM-18029-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0865"(fluorescence acceptor donor pair)	psi-mi:"MI:0865"(fluorescence acceptor donor pair)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034690.3|dip:DIP-5782N|ensembl:ENSMUSG00000021756(gene)|ensembl:ENSMUST00000070731(transcript)|ensembl:ENSMUST00000183663(transcript)|ensembl:ENSMUST00000184311(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004897"(ciliary neurotrophic factor receptor activity)|go:"GO:0004915"(interleukin-6 receptor activity)|go:"GO:0004923"(leukemia inhibitory factor receptor activity)|go:"GO:0004924"(oncostatin-M receptor activity)|go:"GO:0005127"(ciliary neurotrophic factor receptor binding)|go:"GO:0005138"(interleukin-6 receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005896"(interleukin-6 receptor complex)|go:"GO:0005900"(oncostatin-M receptor complex)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019838"(growth factor binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0019981"(interleukin-6 binding)|go:"GO:0030425"(dendrite)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034097"(response to cytokine)|go:"GO:0038154"(interleukin-11-mediated signaling pathway)|go:"GO:0038165"(oncostatin-M-mediated signaling pathway)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0048861"(leukemia inhibitory factor signaling pathway)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0070110"(ciliary neurotrophic factor receptor complex)|go:"GO:0070120"(ciliary neurotrophic factor-mediated signaling pathway)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR010457(Immunoglobulin C2-set-like, ligand-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|mint:Q00560|rcsb pdb:2BBU|rcsb pdb:2HMH|rcsb pdb:4GL9|rcsb pdb:6C5X|reactome:R-MMU-1059683|reactome:R-MMU-110056|reactome:R-MMU-112411|reactome:R-MMU-6788467|reactome:R-MMU-8984722|reactome:R-MMU-9020956|go:"GO:0042102"(positive regulation of T cell proliferation)	ensembl:ENSMUSG00000018341(gene)|ensembl:ENSMUST00000018485(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034097"(response to cytokine)|go:"GO:0043235"(receptor complex)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR010457(Immunoglobulin C2-set-like, ligand-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|mint:P97378|reactome:R-MMU-8984722|reactome:R-MMU-9020591|refseq:NP_001298070.1|refseq:XP_006505680.1|refseq:NP_032380.1	-	-	-	agonist:interaction only present when cell is stimulated with IL-35|figure legend:Fig. 4B.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/07/25	2014/10/16	rogid:DE0EsnNO+FvIfikpCy6T+Ma372Y10090	rogid:pisaSi+DR0Nt3cxmGroWkhoBfbs10090	intact-crc:A68B61D4ADE0B275|rigid:tsKSaFUh1v2EJbB5Ghy77cI74pg	false	green fluorescent protein tag:?-?	mcherry fluorescent protein tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q60837	uniprotkb:P97378	intact:EBI-2481455|uniprotkb:Q3UV59|ensembl:ENSMUSP00000000808	intact:EBI-6253448|ensembl:ENSMUSP00000010605|uniprotkb:B9EHD9	psi-mi:i12r1_mouse(display_long)|uniprotkb:Il12rb1(gene name)|psi-mi:Il12rb1(display_short)|uniprotkb:Il12rb(gene name synonym)|uniprotkb:IL-12 receptor beta component(gene name synonym)	psi-mi:i12r2_mouse(display_long)|uniprotkb:Il12rb2(gene name)|psi-mi:Il12rb2(display_short)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Collison et al. (2012)	pubmed:22306691|imex:IM-18029	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-6253468|imex:IM-18029-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0865"(fluorescence acceptor donor pair)	psi-mi:"MI:0865"(fluorescence acceptor donor pair)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000000791(gene)|ensembl:ENSMUST00000000808(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002827"(positive regulation of T-helper 1 type immune response)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0035722"(interleukin-12-mediated signaling pathway)|go:"GO:0038155"(interleukin-23-mediated signaling pathway)|go:"GO:0042022"(interleukin-12 receptor complex)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0043235"(receptor complex)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072536"(interleukin-23 receptor complex)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|reactome:R-MMU-9020591|reactome:R-MMU-9020933|refseq:NP_032379.2	ensembl:ENSMUSG00000018341(gene)|ensembl:ENSMUST00000018485(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034097"(response to cytokine)|go:"GO:0043235"(receptor complex)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR010457(Immunoglobulin C2-set-like, ligand-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|mint:P97378|reactome:R-MMU-8984722|reactome:R-MMU-9020591|refseq:NP_001298070.1|refseq:XP_006505680.1|refseq:NP_032380.1	-	-	-	agonist:interaction only present when cell is stimulated with IL-12|figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/07/25	2014/10/16	rogid:9Cc5us066C300BwWqKD3d6oi9cI10090	rogid:pisaSi+DR0Nt3cxmGroWkhoBfbs10090	intact-crc:A17EFC5189F9DAE6|rigid:5WMMczlwVWZ3LR2tG8O9VINUC6k	false	green fluorescent protein tag:?-?	mcherry fluorescent protein tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q00560	uniprotkb:Q00560	intact:EBI-3862992|intact:EBI-15596000|uniprotkb:G5E8D2|ensembl:ENSMUSP00000064205|ensembl:ENSMUSP00000138836|ensembl:ENSMUSP00000139227	intact:EBI-3862992|intact:EBI-15596000|uniprotkb:G5E8D2|ensembl:ENSMUSP00000064205|ensembl:ENSMUSP00000138836|ensembl:ENSMUSP00000139227	psi-mi:il6rb_mouse(display_long)|uniprotkb:Il6st(gene name)|psi-mi:Il6st(display_short)|uniprotkb:Interleukin-6 signal transducer(gene name synonym)|uniprotkb:Membrane glycoprotein 130(gene name synonym)|uniprotkb:Oncostatin-M receptor subunit alpha(gene name synonym)	psi-mi:il6rb_mouse(display_long)|uniprotkb:Il6st(gene name)|psi-mi:Il6st(display_short)|uniprotkb:Interleukin-6 signal transducer(gene name synonym)|uniprotkb:Membrane glycoprotein 130(gene name synonym)|uniprotkb:Oncostatin-M receptor subunit alpha(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Collison et al. (2012)	pubmed:22306691|imex:IM-18029	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-6253543|imex:IM-18029-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034690.3|dip:DIP-5782N|ensembl:ENSMUSG00000021756(gene)|ensembl:ENSMUST00000070731(transcript)|ensembl:ENSMUST00000183663(transcript)|ensembl:ENSMUST00000184311(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004897"(ciliary neurotrophic factor receptor activity)|go:"GO:0004915"(interleukin-6 receptor activity)|go:"GO:0004923"(leukemia inhibitory factor receptor activity)|go:"GO:0004924"(oncostatin-M receptor activity)|go:"GO:0005127"(ciliary neurotrophic factor receptor binding)|go:"GO:0005138"(interleukin-6 receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005896"(interleukin-6 receptor complex)|go:"GO:0005900"(oncostatin-M receptor complex)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019838"(growth factor binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0019981"(interleukin-6 binding)|go:"GO:0030425"(dendrite)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034097"(response to cytokine)|go:"GO:0038154"(interleukin-11-mediated signaling pathway)|go:"GO:0038165"(oncostatin-M-mediated signaling pathway)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0048861"(leukemia inhibitory factor signaling pathway)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0070110"(ciliary neurotrophic factor receptor complex)|go:"GO:0070120"(ciliary neurotrophic factor-mediated signaling pathway)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR010457(Immunoglobulin C2-set-like, ligand-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|mint:Q00560|rcsb pdb:2BBU|rcsb pdb:2HMH|rcsb pdb:4GL9|rcsb pdb:6C5X|reactome:R-MMU-1059683|reactome:R-MMU-110056|reactome:R-MMU-112411|reactome:R-MMU-6788467|reactome:R-MMU-8984722|reactome:R-MMU-9020956|go:"GO:0042102"(positive regulation of T cell proliferation)	refseq:NP_034690.3|dip:DIP-5782N|ensembl:ENSMUSG00000021756(gene)|ensembl:ENSMUST00000070731(transcript)|ensembl:ENSMUST00000183663(transcript)|ensembl:ENSMUST00000184311(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004897"(ciliary neurotrophic factor receptor activity)|go:"GO:0004915"(interleukin-6 receptor activity)|go:"GO:0004923"(leukemia inhibitory factor receptor activity)|go:"GO:0004924"(oncostatin-M receptor activity)|go:"GO:0005127"(ciliary neurotrophic factor receptor binding)|go:"GO:0005138"(interleukin-6 receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005896"(interleukin-6 receptor complex)|go:"GO:0005900"(oncostatin-M receptor complex)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019838"(growth factor binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0019981"(interleukin-6 binding)|go:"GO:0030425"(dendrite)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034097"(response to cytokine)|go:"GO:0038154"(interleukin-11-mediated signaling pathway)|go:"GO:0038165"(oncostatin-M-mediated signaling pathway)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0048861"(leukemia inhibitory factor signaling pathway)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0070110"(ciliary neurotrophic factor receptor complex)|go:"GO:0070120"(ciliary neurotrophic factor-mediated signaling pathway)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR010457(Immunoglobulin C2-set-like, ligand-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|mint:Q00560|rcsb pdb:2BBU|rcsb pdb:2HMH|rcsb pdb:4GL9|rcsb pdb:6C5X|reactome:R-MMU-1059683|reactome:R-MMU-110056|reactome:R-MMU-112411|reactome:R-MMU-6788467|reactome:R-MMU-8984722|reactome:R-MMU-9020956|go:"GO:0042102"(positive regulation of T cell proliferation)	-	-	-	figure legend:Fig. 4C, 4D.|agonist:IL35|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/07/25	2014/10/16	rogid:DE0EsnNO+FvIfikpCy6T+Ma372Y10090	rogid:DE0EsnNO+FvIfikpCy6T+Ma372Y10090	intact-crc:F80273128250F836|rigid:TMZW0xL8eyIrCAh1d5h8BPm0dAk	false	green fluorescent protein tag:?-?	mcherry fluorescent protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q00560	uniprotkb:P97378	intact:EBI-3862992|intact:EBI-15596000|uniprotkb:G5E8D2|ensembl:ENSMUSP00000064205|ensembl:ENSMUSP00000138836|ensembl:ENSMUSP00000139227	intact:EBI-6253448|ensembl:ENSMUSP00000010605|uniprotkb:B9EHD9	psi-mi:il6rb_mouse(display_long)|uniprotkb:Il6st(gene name)|psi-mi:Il6st(display_short)|uniprotkb:Interleukin-6 signal transducer(gene name synonym)|uniprotkb:Membrane glycoprotein 130(gene name synonym)|uniprotkb:Oncostatin-M receptor subunit alpha(gene name synonym)	psi-mi:i12r2_mouse(display_long)|uniprotkb:Il12rb2(gene name)|psi-mi:Il12rb2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Collison et al. (2012)	pubmed:22306691|imex:IM-18029	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-6253534|imex:IM-18029-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034690.3|dip:DIP-5782N|ensembl:ENSMUSG00000021756(gene)|ensembl:ENSMUST00000070731(transcript)|ensembl:ENSMUST00000183663(transcript)|ensembl:ENSMUST00000184311(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004897"(ciliary neurotrophic factor receptor activity)|go:"GO:0004915"(interleukin-6 receptor activity)|go:"GO:0004923"(leukemia inhibitory factor receptor activity)|go:"GO:0004924"(oncostatin-M receptor activity)|go:"GO:0005127"(ciliary neurotrophic factor receptor binding)|go:"GO:0005138"(interleukin-6 receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005896"(interleukin-6 receptor complex)|go:"GO:0005900"(oncostatin-M receptor complex)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019838"(growth factor binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0019981"(interleukin-6 binding)|go:"GO:0030425"(dendrite)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034097"(response to cytokine)|go:"GO:0038154"(interleukin-11-mediated signaling pathway)|go:"GO:0038165"(oncostatin-M-mediated signaling pathway)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0048861"(leukemia inhibitory factor signaling pathway)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0070110"(ciliary neurotrophic factor receptor complex)|go:"GO:0070120"(ciliary neurotrophic factor-mediated signaling pathway)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR010457(Immunoglobulin C2-set-like, ligand-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|mint:Q00560|rcsb pdb:2BBU|rcsb pdb:2HMH|rcsb pdb:4GL9|rcsb pdb:6C5X|reactome:R-MMU-1059683|reactome:R-MMU-110056|reactome:R-MMU-112411|reactome:R-MMU-6788467|reactome:R-MMU-8984722|reactome:R-MMU-9020956|go:"GO:0042102"(positive regulation of T cell proliferation)	ensembl:ENSMUSG00000018341(gene)|ensembl:ENSMUST00000018485(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034097"(response to cytokine)|go:"GO:0043235"(receptor complex)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR010457(Immunoglobulin C2-set-like, ligand-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|mint:P97378|reactome:R-MMU-8984722|reactome:R-MMU-9020591|refseq:NP_001298070.1|refseq:XP_006505680.1|refseq:NP_032380.1	-	-	-	figure legend:Fig. 4C, 4D.|agonist:IL35|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/07/25	2014/10/16	rogid:DE0EsnNO+FvIfikpCy6T+Ma372Y10090	rogid:pisaSi+DR0Nt3cxmGroWkhoBfbs10090	intact-crc:13CF1C02F259FE6C|rigid:tsKSaFUh1v2EJbB5Ghy77cI74pg	false	green fluorescent protein tag:?-?	mcherry fluorescent protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P97378	uniprotkb:P97378	intact:EBI-6253448|ensembl:ENSMUSP00000010605|uniprotkb:B9EHD9	intact:EBI-6253448|ensembl:ENSMUSP00000010605|uniprotkb:B9EHD9	psi-mi:i12r2_mouse(display_long)|uniprotkb:Il12rb2(gene name)|psi-mi:Il12rb2(display_short)	psi-mi:i12r2_mouse(display_long)|uniprotkb:Il12rb2(gene name)|psi-mi:Il12rb2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Collison et al. (2012)	pubmed:22306691|imex:IM-18029	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-6253552|imex:IM-18029-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000018341(gene)|ensembl:ENSMUST00000018485(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034097"(response to cytokine)|go:"GO:0043235"(receptor complex)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR010457(Immunoglobulin C2-set-like, ligand-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|mint:P97378|reactome:R-MMU-8984722|reactome:R-MMU-9020591|refseq:NP_001298070.1|refseq:XP_006505680.1|refseq:NP_032380.1	ensembl:ENSMUSG00000018341(gene)|ensembl:ENSMUST00000018485(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034097"(response to cytokine)|go:"GO:0043235"(receptor complex)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR010457(Immunoglobulin C2-set-like, ligand-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|mint:P97378|reactome:R-MMU-8984722|reactome:R-MMU-9020591|refseq:NP_001298070.1|refseq:XP_006505680.1|refseq:NP_032380.1	-	-	-	figure legend:Fig. 4C, 4D.|agonist:IL35|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/07/25	2014/10/16	rogid:pisaSi+DR0Nt3cxmGroWkhoBfbs10090	rogid:pisaSi+DR0Nt3cxmGroWkhoBfbs10090	intact-crc:CC67FCFA7C348353|rigid:qQPg/8M1n+Nl3IzptDgfJ6lBcIM	false	mcherry fluorescent protein tag:?-?	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P97378	uniprotkb:Q60837	intact:EBI-6253448|ensembl:ENSMUSP00000010605|uniprotkb:B9EHD9	intact:EBI-2481455|uniprotkb:Q3UV59|ensembl:ENSMUSP00000000808	psi-mi:i12r2_mouse(display_long)|uniprotkb:Il12rb2(gene name)|psi-mi:Il12rb2(display_short)	psi-mi:i12r1_mouse(display_long)|uniprotkb:Il12rb1(gene name)|psi-mi:Il12rb1(display_short)|uniprotkb:Il12rb(gene name synonym)|uniprotkb:IL-12 receptor beta component(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Collison et al. (2012)	pubmed:22306691|imex:IM-18029	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-6253525|imex:IM-18029-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000018341(gene)|ensembl:ENSMUST00000018485(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034097"(response to cytokine)|go:"GO:0043235"(receptor complex)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR010457(Immunoglobulin C2-set-like, ligand-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|mint:P97378|reactome:R-MMU-8984722|reactome:R-MMU-9020591|refseq:NP_001298070.1|refseq:XP_006505680.1|refseq:NP_032380.1	ensembl:ENSMUSG00000000791(gene)|ensembl:ENSMUST00000000808(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002827"(positive regulation of T-helper 1 type immune response)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0035722"(interleukin-12-mediated signaling pathway)|go:"GO:0038155"(interleukin-23-mediated signaling pathway)|go:"GO:0042022"(interleukin-12 receptor complex)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0043235"(receptor complex)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072536"(interleukin-23 receptor complex)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|reactome:R-MMU-9020591|reactome:R-MMU-9020933|refseq:NP_032379.2	-	-	-	figure legend:Fig. 4C, 4D.|agonist:IL12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2012/07/25	2014/10/16	rogid:pisaSi+DR0Nt3cxmGroWkhoBfbs10090	rogid:9Cc5us066C300BwWqKD3d6oi9cI10090	intact-crc:7FB71B386DE2277F|rigid:5WMMczlwVWZ3LR2tG8O9VINUC6k	false	mcherry fluorescent protein tag:?-?	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P42228	uniprotkb:P42225	intact:EBI-6253572	intact:EBI-647118	psi-mi:stat4_mouse(display_long)|uniprotkb:Stat4(gene name)|psi-mi:Stat4(display_short)	psi-mi:stat1_mouse(display_long)|uniprotkb:Stat1(gene name)|psi-mi:Stat1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Collison et al. (2012)	pubmed:22306691|imex:IM-18029	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-6253570|imex:IM-18029-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0071310"(cellular response to organic substance)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR029839|interpro:IPR035856|interpro:IPR036535|interpro:IPR036860|rcsb pdb:1BGF|interpro:IPR015988(STAT transcription factor, coiled coil)|refseq:NP_001295195.1|refseq:NP_035617.1|dip:DIP-1170N|reactome:R-MMU-8854691|reactome:R-MMU-8984722|reactome:R-MMU-9020591|reactome:R-MMU-9020933|reactome:R-MMU-9020958	dip:DIP-38739N|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009617"(response to bacterium)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005730"(nucleolus)|reactome:R-MMU-1059683|reactome:R-MMU-1169408|reactome:R-MMU-1433557|reactome:R-MMU-186763|reactome:R-MMU-6785807|reactome:R-MMU-877300|reactome:R-MMU-877312|reactome:R-MMU-8854691|reactome:R-MMU-8984722|reactome:R-MMU-8985947|reactome:R-MMU-9020956|reactome:R-MMU-9020958|reactome:R-MMU-909733|reactome:R-MMU-912694|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0034240"(negative regulation of macrophage fusion)|go:"GO:0034340"(response to type I interferon)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042393"(histone binding)|go:"GO:0030425"(dendrite)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022752|interpro:IPR035859|interpro:IPR036535|go:"GO:0051607"(defense response to virus)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0061326"(renal tubule development)|interpro:IPR036860|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071345"(cellular response to cytokine stimulus)|interpro:IPR038295	-	-	-	agonist:IL35|figure legend:Fig. 7C.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-t-cell)|taxid:10090(Mouse T cell)	-	2012/07/25	2014/10/16	rogid:MxJC56kUPN/PBYHJ283JvTTx6jI10090	rogid:0UU+GWFvWO4Uj//otV/IYgwShKg10090	intact-crc:82E44B6F13A2B864|rigid:lXySQ02r00mEn/2fr4rx5GSMxnk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P42228	uniprotkb:P42225	intact:EBI-6253572	intact:EBI-647118	psi-mi:stat4_mouse(display_long)|uniprotkb:Stat4(gene name)|psi-mi:Stat4(display_short)	psi-mi:stat1_mouse(display_long)|uniprotkb:Stat1(gene name)|psi-mi:Stat1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Collison et al. (2012)	pubmed:22306691|imex:IM-18029	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0974"(InnateDB)	intact:EBI-6253602|imex:IM-18029-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0071310"(cellular response to organic substance)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR029839|interpro:IPR035856|interpro:IPR036535|interpro:IPR036860|rcsb pdb:1BGF|interpro:IPR015988(STAT transcription factor, coiled coil)|refseq:NP_001295195.1|refseq:NP_035617.1|dip:DIP-1170N|reactome:R-MMU-8854691|reactome:R-MMU-8984722|reactome:R-MMU-9020591|reactome:R-MMU-9020933|reactome:R-MMU-9020958	dip:DIP-38739N|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009617"(response to bacterium)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005730"(nucleolus)|reactome:R-MMU-1059683|reactome:R-MMU-1169408|reactome:R-MMU-1433557|reactome:R-MMU-186763|reactome:R-MMU-6785807|reactome:R-MMU-877300|reactome:R-MMU-877312|reactome:R-MMU-8854691|reactome:R-MMU-8984722|reactome:R-MMU-8985947|reactome:R-MMU-9020956|reactome:R-MMU-9020958|reactome:R-MMU-909733|reactome:R-MMU-912694|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0034240"(negative regulation of macrophage fusion)|go:"GO:0034340"(response to type I interferon)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042393"(histone binding)|go:"GO:0030425"(dendrite)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022752|interpro:IPR035859|interpro:IPR036535|go:"GO:0051607"(defense response to virus)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0061326"(renal tubule development)|interpro:IPR036860|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071345"(cellular response to cytokine stimulus)|interpro:IPR038295	-	-	-	agonist:IL35|figure legend:Fig. 7C.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-t-cell)|taxid:10090(Mouse T cell)	-	2012/07/25	2014/10/16	rogid:MxJC56kUPN/PBYHJ283JvTTx6jI10090	rogid:0UU+GWFvWO4Uj//otV/IYgwShKg10090	intact-crc:1EEC98594F0812CC|rigid:lXySQ02r00mEn/2fr4rx5GSMxnk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)