#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P0DJH6	uniprotkb:F1NPG5	intact:EBI-2132287|intact:EBI-5481850|ensembl:ENSGALP00000042097	intact:EBI-2132248|ensembl:ENSGALP00000042737	psi-mi:cenpw_chick(display_long)|uniprotkb:CENPW(gene name)|psi-mi:CENPW(display_short)	psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Nishino et al. (2012)	pubmed:22304917|imex:IM-17361	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5481844|wwpdb:3b0d|wwpdb:3b0c|imex:IM-17361-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264662.1|ensembl:ENSGALG00000027454(gene)|ensembl:ENSGALT00000045695(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028847|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6	refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA	-	-	-	3d-r-factors:Rworking =22.0%, Rfree = 26.9%|3d-resolution:2.2A|figure legend:Fig. 1A, Supp. Table 1|comment:Selenomethionine derivatives of the proteins were utilised.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/02/09	2014/10/16	rogid:H65y3on/3Ma0ca00mOoB1YG0E649031	rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031	intact-crc:4AE31B08D5F8B769|rigid:AE1fjjsbTISP28SUn9CqxUvE0PU	false	-	sufficient binding region:531-639|mutation:590-590,607-607	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0DJH7	uniprotkb:E1BSW7	intact:EBI-5590609	intact:EBI-5487792|intact:EBI-5487815|ensembl:ENSGALP00000040599	psi-mi:cenpx_chick(display_long)|uniprotkb:CENPX(gene name)|psi-mi:CENPX(display_short)|uniprotkb:STRA13(gene name synonym)	psi-mi:cenps_chick(display_long)|uniprotkb:CENPS(gene name)|psi-mi:CENPS(display_short)|uniprotkb:APITD1(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Nishino et al. (2012)	pubmed:22304917|imex:IM-17361	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5487823|wwpdb:3B0B|imex:IM-17361-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:7DA0|rcsb pdb:7DA1|rcsb pdb:7DA2|rcsb pdb:3B0B|rcsb pdb:3VH5|rcsb pdb:3VH6|interpro:IPR009072(Histone-fold)|interpro:IPR018552|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0031297"(replication fork processing)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)	refseq:NP_001191861.1|ensembl:ENSGALG00000024481(gene)|ensembl:ENSGALT00000041394(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006281"(DNA repair)|go:"GO:0031297"(replication fork processing)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)|interpro:IPR009072(Histone-fold)|interpro:IPR029003|interpro:IPR033554|rcsb pdb:3B0B|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:7DA0|rcsb pdb:7DA1|rcsb pdb:7DA2	-	-	comment:Similar to Q8C4X1	3d-resolution:2.15A|3d-r-factors:Rworking 18.6%, Rfree 21.8%|figure legend:Fig. 2A, Supp. Table 2|comment:Selenomethionine derivatives of the proteins were utilized.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/02/09	2014/10/16	rogid:eBLUG+lviRSMIj5czcJ0G68Zx7c9031	rogid:SxvvkuUYD1adN556gSg/dHbiKYc9031	intact-crc:376916D7D4BC5665|rigid:dC76gogN8JNvvguzdcgrxOElHwo	false	-	sufficient binding region:1-106	2	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0DJH6	uniprotkb:F1NPG5	intact:EBI-2132287|intact:EBI-5481850|ensembl:ENSGALP00000042097	intact:EBI-2132248|ensembl:ENSGALP00000042737	psi-mi:cenpw_chick(display_long)|uniprotkb:CENPW(gene name)|psi-mi:CENPW(display_short)	psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short)	psi-mi:"MI:0071"(molecular sieving)	Nishino et al. (2012)	pubmed:22304917|imex:IM-17361	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5529336|imex:IM-17361-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001264662.1|ensembl:ENSGALG00000027454(gene)|ensembl:ENSGALT00000045695(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028847|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6	refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA	-	-	-	figure legend:Fig. 4B, 4E, Supp. Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/02/09	2014/10/16	rogid:H65y3on/3Ma0ca00mOoB1YG0E649031	rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031	intact-crc:D37E4880130757F5|rigid:AE1fjjsbTISP28SUn9CqxUvE0PU	false	-	mutation:607-607,590-590|sufficient binding region:531-639	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:E1BSW7	uniprotkb:F1NPG5	intact:EBI-5487792|intact:EBI-5487815|ensembl:ENSGALP00000040599	intact:EBI-2132248|ensembl:ENSGALP00000042737	psi-mi:cenps_chick(display_long)|uniprotkb:CENPS(gene name)|psi-mi:CENPS(display_short)|uniprotkb:APITD1(gene name synonym)	psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short)	psi-mi:"MI:0071"(molecular sieving)	Nishino et al. (2012)	pubmed:22304917|imex:IM-17361	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5529604|imex:IM-17361-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191861.1|ensembl:ENSGALG00000024481(gene)|ensembl:ENSGALT00000041394(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006281"(DNA repair)|go:"GO:0031297"(replication fork processing)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)|interpro:IPR009072(Histone-fold)|interpro:IPR029003|interpro:IPR033554|rcsb pdb:3B0B|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:7DA0|rcsb pdb:7DA1|rcsb pdb:7DA2	refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA	-	comment:Similar to Q8C4X1	-	figure legend:Fig. 4B,Supp. Fig. 4A|comment:CenpS lacking the C-terminal 33 amino acids also bound in the complex.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/02/09	2014/10/16	rogid:SxvvkuUYD1adN556gSg/dHbiKYc9031	rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031	intact-crc:7FAB10AE2EB5B25D|rigid:ARKjiGeFLSG36jFwpAUw3F++XGw	false	sufficient binding region:1-106	sufficient binding region:531-639|mutation:607-607,590-590	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:E1BSW7	uniprotkb:P0DJH6	intact:EBI-5487792|intact:EBI-5487815|ensembl:ENSGALP00000040599	intact:EBI-2132287|intact:EBI-5481850|ensembl:ENSGALP00000042097	psi-mi:cenps_chick(display_long)|uniprotkb:CENPS(gene name)|psi-mi:CENPS(display_short)|uniprotkb:APITD1(gene name synonym)	psi-mi:cenpw_chick(display_long)|uniprotkb:CENPW(gene name)|psi-mi:CENPW(display_short)	psi-mi:"MI:0071"(molecular sieving)	Nishino et al. (2012)	pubmed:22304917|imex:IM-17361	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5529604|imex:IM-17361-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191861.1|ensembl:ENSGALG00000024481(gene)|ensembl:ENSGALT00000041394(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006281"(DNA repair)|go:"GO:0031297"(replication fork processing)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)|interpro:IPR009072(Histone-fold)|interpro:IPR029003|interpro:IPR033554|rcsb pdb:3B0B|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:7DA0|rcsb pdb:7DA1|rcsb pdb:7DA2	refseq:NP_001264662.1|ensembl:ENSGALG00000027454(gene)|ensembl:ENSGALT00000045695(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028847|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6	-	comment:Similar to Q8C4X1	-	figure legend:Fig. 4B,Supp. Fig. 4A|comment:CenpS lacking the C-terminal 33 amino acids also bound in the complex.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/02/09	2014/10/16	rogid:SxvvkuUYD1adN556gSg/dHbiKYc9031	rogid:H65y3on/3Ma0ca00mOoB1YG0E649031	intact-crc:7FAB10AE2EB5B25D|rigid:ARKjiGeFLSG36jFwpAUw3F++XGw	false	sufficient binding region:1-106	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:E1BSW7	uniprotkb:P0DJH7	intact:EBI-5487792|intact:EBI-5487815|ensembl:ENSGALP00000040599	intact:EBI-5590609	psi-mi:cenps_chick(display_long)|uniprotkb:CENPS(gene name)|psi-mi:CENPS(display_short)|uniprotkb:APITD1(gene name synonym)	psi-mi:cenpx_chick(display_long)|uniprotkb:CENPX(gene name)|psi-mi:CENPX(display_short)|uniprotkb:STRA13(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Nishino et al. (2012)	pubmed:22304917|imex:IM-17361	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5529604|imex:IM-17361-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001191861.1|ensembl:ENSGALG00000024481(gene)|ensembl:ENSGALT00000041394(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006281"(DNA repair)|go:"GO:0031297"(replication fork processing)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)|interpro:IPR009072(Histone-fold)|interpro:IPR029003|interpro:IPR033554|rcsb pdb:3B0B|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:7DA0|rcsb pdb:7DA1|rcsb pdb:7DA2	rcsb pdb:7DA0|rcsb pdb:7DA1|rcsb pdb:7DA2|rcsb pdb:3B0B|rcsb pdb:3VH5|rcsb pdb:3VH6|interpro:IPR009072(Histone-fold)|interpro:IPR018552|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0031297"(replication fork processing)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)	-	comment:Similar to Q8C4X1	-	figure legend:Fig. 4B,Supp. Fig. 4A|comment:CenpS lacking the C-terminal 33 amino acids also bound in the complex.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/02/09	2014/10/16	rogid:SxvvkuUYD1adN556gSg/dHbiKYc9031	rogid:eBLUG+lviRSMIj5czcJ0G68Zx7c9031	intact-crc:7FAB10AE2EB5B25D|rigid:ARKjiGeFLSG36jFwpAUw3F++XGw	false	sufficient binding region:1-106	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0DJH7	uniprotkb:E1BSW7	intact:EBI-5590609	intact:EBI-5487792|intact:EBI-5487815|ensembl:ENSGALP00000040599	psi-mi:cenpx_chick(display_long)|uniprotkb:CENPX(gene name)|psi-mi:CENPX(display_short)|uniprotkb:STRA13(gene name synonym)	psi-mi:cenps_chick(display_long)|uniprotkb:CENPS(gene name)|psi-mi:CENPS(display_short)|uniprotkb:APITD1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Nishino et al. (2012)	pubmed:22304917|imex:IM-17361	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5529357|imex:IM-17361-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:7DA0|rcsb pdb:7DA1|rcsb pdb:7DA2|rcsb pdb:3B0B|rcsb pdb:3VH5|rcsb pdb:3VH6|interpro:IPR009072(Histone-fold)|interpro:IPR018552|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0031297"(replication fork processing)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)	refseq:NP_001191861.1|ensembl:ENSGALG00000024481(gene)|ensembl:ENSGALT00000041394(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006281"(DNA repair)|go:"GO:0031297"(replication fork processing)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)|interpro:IPR009072(Histone-fold)|interpro:IPR029003|interpro:IPR033554|rcsb pdb:3B0B|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:7DA0|rcsb pdb:7DA1|rcsb pdb:7DA2	-	-	comment:Similar to Q8C4X1	figure legend:Supp Fig 2B, 2C|comment:Mutations cause protein to dimerize rather than tetramize. Loss of the C-terminal 33 amino acids also prevented tetramerization. Tetramerization of the CENP-S-X complex is also required for full DNA binding activity|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/02/09	2014/10/16	rogid:eBLUG+lviRSMIj5czcJ0G68Zx7c9031	rogid:SxvvkuUYD1adN556gSg/dHbiKYc9031	intact-crc:8FB8387D13E3CA2B|rigid:dC76gogN8JNvvguzdcgrxOElHwo	false	-	mutation:68-68,65-65,81-81,84-84|sufficient binding region:1-106	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0DJH7	uniprotkb:E1BSW7	intact:EBI-5590609	intact:EBI-5487792|intact:EBI-5487815|ensembl:ENSGALP00000040599	psi-mi:cenpx_chick(display_long)|uniprotkb:CENPX(gene name)|psi-mi:CENPX(display_short)|uniprotkb:STRA13(gene name synonym)	psi-mi:cenps_chick(display_long)|uniprotkb:CENPS(gene name)|psi-mi:CENPS(display_short)|uniprotkb:APITD1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Nishino et al. (2012)	pubmed:22304917|imex:IM-17361	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5529342|imex:IM-17361-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:7DA0|rcsb pdb:7DA1|rcsb pdb:7DA2|rcsb pdb:3B0B|rcsb pdb:3VH5|rcsb pdb:3VH6|interpro:IPR009072(Histone-fold)|interpro:IPR018552|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0031297"(replication fork processing)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)	refseq:NP_001191861.1|ensembl:ENSGALG00000024481(gene)|ensembl:ENSGALT00000041394(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006281"(DNA repair)|go:"GO:0031297"(replication fork processing)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)|interpro:IPR009072(Histone-fold)|interpro:IPR029003|interpro:IPR033554|rcsb pdb:3B0B|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:7DA0|rcsb pdb:7DA1|rcsb pdb:7DA2	-	-	comment:Similar to Q8C4X1	figure legend:Fig. 4B, 4E, Supp. Fig. 2B, 3A, 4A|comment:"Mutant CENP-S-X complexes (containing CENP-S [R15A, K41A, K70A] or CENP-X [R9A, R27A, K62A]; bind but are defective in   DNA binding."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/02/09	2014/10/16	rogid:eBLUG+lviRSMIj5czcJ0G68Zx7c9031	rogid:SxvvkuUYD1adN556gSg/dHbiKYc9031	intact-crc:42163FBC5AC877B9|rigid:dC76gogN8JNvvguzdcgrxOElHwo	false	-	-	2	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BT3	uniprotkb:Q5EE01	intact:EBI-719918|uniprotkb:Q96I29|uniprotkb:Q96IC6|uniprotkb:Q96NK9|uniprotkb:Q9H901|ensembl:ENSP00000400140|ensembl:ENSP00000457810	intact:EBI-5529625|uniprotkb:A6NIR0|uniprotkb:A6NJC2|ensembl:ENSP00000357311	psi-mi:cenpt_human(display_long)|uniprotkb:Interphase centromere complex protein 22(gene name synonym)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short)|uniprotkb:C16orf56(gene name synonym)|uniprotkb:ICEN22(gene name synonym)	psi-mi:cenpw_human(display_long)|uniprotkb:CENPW(gene name)|psi-mi:CENPW(display_short)|uniprotkb:C6orf173(gene name synonym)|uniprotkb:CUG2(gene name synonym)|uniprotkb:Cancer-up-regulated gene 2 protein(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Nishino et al. (2012)	pubmed:22304917|imex:IM-17361	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5529641|imex:IM-17361-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079358.3|ensembl:ENSG00000102901(gene)|ensembl:ENST00000440851(transcript)|ensembl:ENST00000562787(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025	refseq:NP_001273453.1|refseq:NP_001273454.1|refseq:XP_016866334.1|refseq:NP_001012525.1|ensembl:ENSG00000203760(gene)|ensembl:ENST00000368328(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028847|reactome:R-HSA-606279	-	-	-	figure legend:Supp. Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/02/09	2014/10/16	rogid:TVIRAvfopdj+sRVaAOHj5xxYssg9606	rogid:VjmwyoKpkctsRtYcwbGlVtlQahc9606	intact-crc:4638D90A065EBA15|rigid:RcLiMq8JK2CRhHkib26XzwWiZGk	false	his tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N2Z9	uniprotkb:A8MT69	intact:EBI-5529649|uniprotkb:Q8NFE5|uniprotkb:Q8NFG5|ensembl:ENSP00000308583	intact:EBI-5529694|uniprotkb:O00281|uniprotkb:O00282|uniprotkb:Q96DD4|uniprotkb:Q96F51|ensembl:ENSP00000376168	psi-mi:cenps_human(display_long)|uniprotkb:CENPS(gene name)|psi-mi:CENPS(display_short)|uniprotkb:APITD1(gene name synonym)|uniprotkb:Apoptosis-inducing TAF9-like domain-containing protein 1(gene name synonym)|uniprotkb:FAAP16(gene name synonym)|uniprotkb:FANCM-associated histone fold protein 1(gene name synonym)|uniprotkb:FANCM-interacting histone fold protein 1(gene name synonym)|uniprotkb:Fanconi anemia-associated polypeptide of 16 kDa(gene name synonym)|uniprotkb:MHF1(gene name synonym)	psi-mi:cenpx_human(display_long)|uniprotkb:CENPX(gene name)|psi-mi:CENPX(display_short)|uniprotkb:FAAP10(gene name synonym)|uniprotkb:FANCM-associated histone fold protein 2(gene name synonym)|uniprotkb:FANCM-interacting histone fold protein 2(gene name synonym)|uniprotkb:Fanconi anemia-associated polypeptide of 10 kDa(gene name synonym)|uniprotkb:MHF2(gene name synonym)|uniprotkb:Retinoic acid-inducible gene D9 protein homolog(gene name synonym)|uniprotkb:STRA13(gene name synonym)|uniprotkb:Stimulated by retinoic acid gene 13 protein homolog(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Nishino et al. (2012)	pubmed:22304917|imex:IM-17361	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5529685|imex:IM-17361-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_940946.1|refseq:NP_950171.2|refseq:NP_954988.1|refseq:NP_001257446.1|go:"GO:0031398"(positive regulation of protein ubiquitination)|ensembl:ENSG00000175279(gene)|ensembl:ENST00000309048(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)|interpro:IPR009072(Histone-fold)|interpro:IPR029003|interpro:IPR033554|rcsb pdb:4DRA|rcsb pdb:4DRB|rcsb pdb:4E44|rcsb pdb:4E45|rcsb pdb:4NDY|rcsb pdb:4NE1|rcsb pdb:4NE3|rcsb pdb:4NE5|rcsb pdb:4NE6|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-6783310|reactome:R-HSA-68877|reactome:R-HSA-9648025	refseq:NP_659435.2|refseq:NP_001257935.1|refseq:NP_001257936.1|refseq:NP_001317465.1|ensembl:ENSG00000169689(gene)|ensembl:ENST00000392359(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0031297"(replication fork processing)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)|interpro:IPR018552|rcsb pdb:4DRA|rcsb pdb:4DRB|rcsb pdb:4E44|rcsb pdb:4E45|rcsb pdb:4NDY|rcsb pdb:4NE1|rcsb pdb:4NE3|rcsb pdb:4NE5|rcsb pdb:4NE6|reactome:R-HSA-606279|reactome:R-HSA-6783310	-	-	-	figure legend:Supp. Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/02/09	2014/10/16	rogid:xxVqqdZ7dcp6/CR0aJzd2qMNYNE9606	rogid:CwD7kVdQX6u8LJVlcqL/SbDxOg09606	intact-crc:3A13A71834415CDA|rigid:pIs6AihU6lR7jzlIocKUJFLwLJQ	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N2Z9	uniprotkb:Q96BT3	intact:EBI-5529649|uniprotkb:Q8NFE5|uniprotkb:Q8NFG5|ensembl:ENSP00000308583	intact:EBI-719918|uniprotkb:Q96I29|uniprotkb:Q96IC6|uniprotkb:Q96NK9|uniprotkb:Q9H901|ensembl:ENSP00000400140|ensembl:ENSP00000457810	psi-mi:cenps_human(display_long)|uniprotkb:CENPS(gene name)|psi-mi:CENPS(display_short)|uniprotkb:APITD1(gene name synonym)|uniprotkb:Apoptosis-inducing TAF9-like domain-containing protein 1(gene name synonym)|uniprotkb:FAAP16(gene name synonym)|uniprotkb:FANCM-associated histone fold protein 1(gene name synonym)|uniprotkb:FANCM-interacting histone fold protein 1(gene name synonym)|uniprotkb:Fanconi anemia-associated polypeptide of 16 kDa(gene name synonym)|uniprotkb:MHF1(gene name synonym)	psi-mi:cenpt_human(display_long)|uniprotkb:Interphase centromere complex protein 22(gene name synonym)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short)|uniprotkb:C16orf56(gene name synonym)|uniprotkb:ICEN22(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Nishino et al. (2012)	pubmed:22304917|imex:IM-17361	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5529689|imex:IM-17361-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_940946.1|refseq:NP_950171.2|refseq:NP_954988.1|refseq:NP_001257446.1|go:"GO:0031398"(positive regulation of protein ubiquitination)|ensembl:ENSG00000175279(gene)|ensembl:ENST00000309048(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)|interpro:IPR009072(Histone-fold)|interpro:IPR029003|interpro:IPR033554|rcsb pdb:4DRA|rcsb pdb:4DRB|rcsb pdb:4E44|rcsb pdb:4E45|rcsb pdb:4NDY|rcsb pdb:4NE1|rcsb pdb:4NE3|rcsb pdb:4NE5|rcsb pdb:4NE6|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-6783310|reactome:R-HSA-68877|reactome:R-HSA-9648025	refseq:NP_079358.3|ensembl:ENSG00000102901(gene)|ensembl:ENST00000440851(transcript)|ensembl:ENST00000562787(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025	-	-	-	figure legend:Supp. Fig. 4B|comment:The N-terminus of CENPT is not required for bindingto the complex.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/02/09	2014/10/16	rogid:xxVqqdZ7dcp6/CR0aJzd2qMNYNE9606	rogid:TVIRAvfopdj+sRVaAOHj5xxYssg9606	intact-crc:08D518E21FBDC0F9|rigid:2xDIX3nkrnlQZfrx7kwYAUXk9tg	false	-	his tag:?-?	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N2Z9	uniprotkb:Q5EE01	intact:EBI-5529649|uniprotkb:Q8NFE5|uniprotkb:Q8NFG5|ensembl:ENSP00000308583	intact:EBI-5529625|uniprotkb:A6NIR0|uniprotkb:A6NJC2|ensembl:ENSP00000357311	psi-mi:cenps_human(display_long)|uniprotkb:CENPS(gene name)|psi-mi:CENPS(display_short)|uniprotkb:APITD1(gene name synonym)|uniprotkb:Apoptosis-inducing TAF9-like domain-containing protein 1(gene name synonym)|uniprotkb:FAAP16(gene name synonym)|uniprotkb:FANCM-associated histone fold protein 1(gene name synonym)|uniprotkb:FANCM-interacting histone fold protein 1(gene name synonym)|uniprotkb:Fanconi anemia-associated polypeptide of 16 kDa(gene name synonym)|uniprotkb:MHF1(gene name synonym)	psi-mi:cenpw_human(display_long)|uniprotkb:CENPW(gene name)|psi-mi:CENPW(display_short)|uniprotkb:C6orf173(gene name synonym)|uniprotkb:CUG2(gene name synonym)|uniprotkb:Cancer-up-regulated gene 2 protein(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Nishino et al. (2012)	pubmed:22304917|imex:IM-17361	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5529689|imex:IM-17361-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_940946.1|refseq:NP_950171.2|refseq:NP_954988.1|refseq:NP_001257446.1|go:"GO:0031398"(positive regulation of protein ubiquitination)|ensembl:ENSG00000175279(gene)|ensembl:ENST00000309048(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)|interpro:IPR009072(Histone-fold)|interpro:IPR029003|interpro:IPR033554|rcsb pdb:4DRA|rcsb pdb:4DRB|rcsb pdb:4E44|rcsb pdb:4E45|rcsb pdb:4NDY|rcsb pdb:4NE1|rcsb pdb:4NE3|rcsb pdb:4NE5|rcsb pdb:4NE6|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-6783310|reactome:R-HSA-68877|reactome:R-HSA-9648025	refseq:NP_001273453.1|refseq:NP_001273454.1|refseq:XP_016866334.1|refseq:NP_001012525.1|ensembl:ENSG00000203760(gene)|ensembl:ENST00000368328(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028847|reactome:R-HSA-606279	-	-	-	figure legend:Supp. Fig. 4B|comment:The N-terminus of CENPT is not required for bindingto the complex.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/02/09	2014/10/16	rogid:xxVqqdZ7dcp6/CR0aJzd2qMNYNE9606	rogid:VjmwyoKpkctsRtYcwbGlVtlQahc9606	intact-crc:08D518E21FBDC0F9|rigid:2xDIX3nkrnlQZfrx7kwYAUXk9tg	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8N2Z9	uniprotkb:A8MT69	intact:EBI-5529649|uniprotkb:Q8NFE5|uniprotkb:Q8NFG5|ensembl:ENSP00000308583	intact:EBI-5529694|uniprotkb:O00281|uniprotkb:O00282|uniprotkb:Q96DD4|uniprotkb:Q96F51|ensembl:ENSP00000376168	psi-mi:cenps_human(display_long)|uniprotkb:CENPS(gene name)|psi-mi:CENPS(display_short)|uniprotkb:APITD1(gene name synonym)|uniprotkb:Apoptosis-inducing TAF9-like domain-containing protein 1(gene name synonym)|uniprotkb:FAAP16(gene name synonym)|uniprotkb:FANCM-associated histone fold protein 1(gene name synonym)|uniprotkb:FANCM-interacting histone fold protein 1(gene name synonym)|uniprotkb:Fanconi anemia-associated polypeptide of 16 kDa(gene name synonym)|uniprotkb:MHF1(gene name synonym)	psi-mi:cenpx_human(display_long)|uniprotkb:CENPX(gene name)|psi-mi:CENPX(display_short)|uniprotkb:FAAP10(gene name synonym)|uniprotkb:FANCM-associated histone fold protein 2(gene name synonym)|uniprotkb:FANCM-interacting histone fold protein 2(gene name synonym)|uniprotkb:Fanconi anemia-associated polypeptide of 10 kDa(gene name synonym)|uniprotkb:MHF2(gene name synonym)|uniprotkb:Retinoic acid-inducible gene D9 protein homolog(gene name synonym)|uniprotkb:STRA13(gene name synonym)|uniprotkb:Stimulated by retinoic acid gene 13 protein homolog(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Nishino et al. (2012)	pubmed:22304917|imex:IM-17361	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5529689|imex:IM-17361-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_940946.1|refseq:NP_950171.2|refseq:NP_954988.1|refseq:NP_001257446.1|go:"GO:0031398"(positive regulation of protein ubiquitination)|ensembl:ENSG00000175279(gene)|ensembl:ENST00000309048(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)|interpro:IPR009072(Histone-fold)|interpro:IPR029003|interpro:IPR033554|rcsb pdb:4DRA|rcsb pdb:4DRB|rcsb pdb:4E44|rcsb pdb:4E45|rcsb pdb:4NDY|rcsb pdb:4NE1|rcsb pdb:4NE3|rcsb pdb:4NE5|rcsb pdb:4NE6|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-6783310|reactome:R-HSA-68877|reactome:R-HSA-9648025	refseq:NP_659435.2|refseq:NP_001257935.1|refseq:NP_001257936.1|refseq:NP_001317465.1|ensembl:ENSG00000169689(gene)|ensembl:ENST00000392359(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0031297"(replication fork processing)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)|interpro:IPR018552|rcsb pdb:4DRA|rcsb pdb:4DRB|rcsb pdb:4E44|rcsb pdb:4E45|rcsb pdb:4NDY|rcsb pdb:4NE1|rcsb pdb:4NE3|rcsb pdb:4NE5|rcsb pdb:4NE6|reactome:R-HSA-606279|reactome:R-HSA-6783310	-	-	-	figure legend:Supp. Fig. 4B|comment:The N-terminus of CENPT is not required for bindingto the complex.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/02/09	2014/10/16	rogid:xxVqqdZ7dcp6/CR0aJzd2qMNYNE9606	rogid:CwD7kVdQX6u8LJVlcqL/SbDxOg09606	intact-crc:08D518E21FBDC0F9|rigid:2xDIX3nkrnlQZfrx7kwYAUXk9tg	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:F1NPG5	uniprotkb:E1BSW7	intact:EBI-2132248|ensembl:ENSGALP00000042737	intact:EBI-5487792|intact:EBI-5487815|ensembl:ENSGALP00000040599	psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short)	psi-mi:cenps_chick(display_long)|uniprotkb:CENPS(gene name)|psi-mi:CENPS(display_short)|uniprotkb:APITD1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Nishino et al. (2012)	pubmed:22304917|imex:IM-17361	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5529746|imex:IM-17361-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA	refseq:NP_001191861.1|ensembl:ENSGALG00000024481(gene)|ensembl:ENSGALT00000041394(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006281"(DNA repair)|go:"GO:0031297"(replication fork processing)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)|interpro:IPR009072(Histone-fold)|interpro:IPR029003|interpro:IPR033554|rcsb pdb:3B0B|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:7DA0|rcsb pdb:7DA1|rcsb pdb:7DA2	-	-	comment:Similar to Q8C4X1	figure legend:Supp. 3B|comment:CENPS mutant defective in DNA binding still bound CENPT.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-dt40)|taxid:9031(Gallus gallus bursa lymphoma)	-	2012/02/09	2014/10/16	rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031	rogid:SxvvkuUYD1adN556gSg/dHbiKYc9031	intact-crc:0EC861D9CF995013|rigid:11LMzM99rSxbiNgqvCRyiJgMXwc	false	-	mutation:65-65,68-68,81-81,84-84|red fluorescent protein tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:F1NPG5	uniprotkb:E1BSW7	intact:EBI-2132248|ensembl:ENSGALP00000042737	intact:EBI-5487792|intact:EBI-5487815|ensembl:ENSGALP00000040599	psi-mi:cenpt_chick(display_long)|uniprotkb:CENPT(gene name)|psi-mi:CENPT(display_short)	psi-mi:cenps_chick(display_long)|uniprotkb:CENPS(gene name)|psi-mi:CENPS(display_short)|uniprotkb:APITD1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Nishino et al. (2012)	pubmed:22304917|imex:IM-17361	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-6143075|imex:IM-17361-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001263242.1|ensembl:ENSGALG00000028900(gene)|ensembl:ENSGALT00000043964(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:1903394"(protein localization to kinetochore involved in kinetochore assembly)|interpro:IPR009072(Histone-fold)|interpro:IPR028255|interpro:IPR032373|interpro:IPR035425|rcsb pdb:3B0C|rcsb pdb:3B0D|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:3VZA	refseq:NP_001191861.1|ensembl:ENSGALG00000024481(gene)|ensembl:ENSGALT00000041394(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0006281"(DNA repair)|go:"GO:0031297"(replication fork processing)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0071821"(FANCM-MHF complex)|interpro:IPR009072(Histone-fold)|interpro:IPR029003|interpro:IPR033554|rcsb pdb:3B0B|rcsb pdb:3VH5|rcsb pdb:3VH6|rcsb pdb:7DA0|rcsb pdb:7DA1|rcsb pdb:7DA2	-	-	comment:Similar to Q8C4X1	figure legend:Supp. 3B|comment:CENPS mutant defective in DNA binding still bound CENPT.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9031(chick-dt40)|taxid:9031(Gallus gallus bursa lymphoma)	-	2012/02/09	2014/10/16	rogid:kRNRHK5vtM8zuKPUe8EHn/G7U6E9031	rogid:SxvvkuUYD1adN556gSg/dHbiKYc9031	intact-crc:3546B3BD8CBC47CE|rigid:11LMzM99rSxbiNgqvCRyiJgMXwc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)