#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P07320 uniprotkb:P23927 intact:EBI-7673124|ensembl:ENSP00000264376|ensembl:ENSP00000496652|uniprotkb:Q53R51|intact:MINT-8303016|uniprotkb:Q17RF7|uniprotkb:Q99681 intact:EBI-299046|ensembl:ENSMUSP00000034562|ensembl:ENSMUSP00000149759|ensembl:ENSMUSP00000149803|ensembl:ENSMUSP00000150669|uniprotkb:Q64325 psi-mi:crgd_human(display_long)|uniprotkb:Gamma-crystallin 4(gene name synonym)|uniprotkb:CRYGD(gene name)|psi-mi:CRYGD(display_short)|uniprotkb:CRYG4(gene name synonym)|uniprotkb:Gamma-D-crystallin(gene name synonym) psi-mi:cryab_mouse(display_long)|uniprotkb:Cryab(gene name)|psi-mi:Cryab(display_short)|uniprotkb:Crya2(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:P23(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Mishra et al. (2012) pubmed:22289178|imex:IM-16817|mint:MINT-8303011|mint:d-11-02016 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7673116|mint:MINT-8303035|imex:IM-16817-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070306"(lens fiber cell differentiation)|ensembl:ENSG00000118231(gene)|ensembl:ENSG00000285434(gene)|ensembl:ENST00000264376(transcript)|ensembl:ENST00000644920(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005212"(structural constituent of eye lens)|interpro:IPR001064(Beta and gamma crystallin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007601"(visual perception)|go:"GO:0034614"(cellular response to reactive oxygen species)|interpro:IPR011024(Gamma-crystallin related)|rcsb pdb:1H4A|rcsb pdb:1HK0|rcsb pdb:1LD0|rcsb pdb:2G98|rcsb pdb:2KFB|rcsb pdb:2KLJ|rcsb pdb:4GR7|rcsb pdb:4JGF|rcsb pdb:6ETA|rcsb pdb:6ETC|rcsb pdb:6W5B|rcsb pdb:6WCY|refseq:NP_008822.2|dip:DIP-46208N|mint:MINT-8303037(identity) ensembl:ENSMUSG00000032060(gene)|ensembl:ENSMUST00000034562(transcript)|ensembl:ENSMUST00000214962(transcript)|ensembl:ENSMUST00000216755(transcript)|ensembl:ENSMUST00000217475(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043292"(contractile fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P23927|reactome:R-MMU-3371571|refseq:XP_006510033.1|refseq:NP_034094.1|refseq:NP_001276711.1|refseq:NP_001276713.1|refseq:NP_001276714.1|dip:DIP-31060N|mint:MINT-8303038(identity) - comment:mint|comment:homomint - comment:homomint|comment:mint|figure legend:f5b f5c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/01/13 2014/10/16 rogid:qU4whgmCS9+Zq9udbDIhSLFLV0s9606 rogid:LOp5smbeRceV8/P+Eaoh7p+24Vw10090 intact-crc:0CBAE83F98175A1C|rigid:w3i8VC77M2pnh2P5xCzDiGZ5Afc false mutation increasing interaction:4-4(MINT-8303041)|mutation increasing interaction:76-76(MINT-8303044) mutation increasing interaction:45-45(MINT-8303054)|mutation increasing interaction:19-19(MINT-8303051)|mutation increasing interaction:59-59(MINT-8303057) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P24623 uniprotkb:P07320 intact:EBI-7673244|ensembl:ENSRNOP00000065714|uniprotkb:Q61444|uniprotkb:P02496|uniprotkb:P02490|uniprotkb:P82532|intact:MINT-8303018 intact:EBI-7673124|ensembl:ENSP00000264376|ensembl:ENSP00000496652|uniprotkb:Q53R51|intact:MINT-8303016|uniprotkb:Q17RF7|uniprotkb:Q99681 psi-mi:cryaa_rat(display_long)|uniprotkb:Cryaa(gene name)|psi-mi:Cryaa(display_short)|uniprotkb:Crya1(gene name synonym) psi-mi:crgd_human(display_long)|uniprotkb:Gamma-crystallin 4(gene name synonym)|uniprotkb:CRYGD(gene name)|psi-mi:CRYGD(display_short)|uniprotkb:CRYG4(gene name synonym)|uniprotkb:Gamma-D-crystallin(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Mishra et al. (2012) pubmed:22289178|imex:IM-16817|mint:MINT-8303011|mint:d-11-02016 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7673297|mint:MINT-8303127|imex:IM-16817-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007601"(visual perception)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010288"(response to lead ion)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|ensembl:ENSRNOG00000047175(gene)|ensembl:ENSRNOT00000075545(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070141"(response to UV-A)|go:"GO:0070309"(lens fiber cell morphogenesis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR012274(Alpha-crystallin, subunit A)|go:"GO:0046872"(metal ion binding)|rgd:2413|refseq:NP_036666.2|refseq:NP_001276666.1|mint:MINT-8303135(identity) go:"GO:0070306"(lens fiber cell differentiation)|ensembl:ENSG00000118231(gene)|ensembl:ENSG00000285434(gene)|ensembl:ENST00000264376(transcript)|ensembl:ENST00000644920(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005212"(structural constituent of eye lens)|interpro:IPR001064(Beta and gamma crystallin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007601"(visual perception)|go:"GO:0034614"(cellular response to reactive oxygen species)|interpro:IPR011024(Gamma-crystallin related)|rcsb pdb:1H4A|rcsb pdb:1HK0|rcsb pdb:1LD0|rcsb pdb:2G98|rcsb pdb:2KFB|rcsb pdb:2KLJ|rcsb pdb:4GR7|rcsb pdb:4JGF|rcsb pdb:6ETA|rcsb pdb:6ETC|rcsb pdb:6W5B|rcsb pdb:6WCY|refseq:NP_008822.2|dip:DIP-46208N|mint:MINT-8303129(identity) - comment:mint comment:mint|comment:homomint figure legend:f5a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/01/13 2014/10/16 rogid:VRK116L/kz6hQZKms/qSNi+iVhw10116 rogid:qU4whgmCS9+Zq9udbDIhSLFLV0s9606 intact-crc:D78AD4DBD4835263|rigid:KcjqGj/quN1F8k96RNf72aJhckw false - mutation increasing interaction:76-76(MINT-8303130)|mutation increasing interaction:4-4(MINT-8303132) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07320 uniprotkb:P24623 intact:EBI-7673124|ensembl:ENSP00000264376|ensembl:ENSP00000496652|uniprotkb:Q53R51|intact:MINT-8303016|uniprotkb:Q17RF7|uniprotkb:Q99681 intact:EBI-7673244|ensembl:ENSRNOP00000065714|uniprotkb:Q61444|uniprotkb:P02496|uniprotkb:P02490|uniprotkb:P82532|intact:MINT-8303018 psi-mi:crgd_human(display_long)|uniprotkb:Gamma-crystallin 4(gene name synonym)|uniprotkb:CRYGD(gene name)|psi-mi:CRYGD(display_short)|uniprotkb:CRYG4(gene name synonym)|uniprotkb:Gamma-D-crystallin(gene name synonym) psi-mi:cryaa_rat(display_long)|uniprotkb:Cryaa(gene name)|psi-mi:Cryaa(display_short)|uniprotkb:Crya1(gene name synonym) psi-mi:"MI:0051"(fluorescence technology) Mishra et al. (2012) pubmed:22289178|imex:IM-16817|mint:MINT-8303011|mint:d-11-02016 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7673369|mint:MINT-8303079|imex:IM-16817-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070306"(lens fiber cell differentiation)|ensembl:ENSG00000118231(gene)|ensembl:ENSG00000285434(gene)|ensembl:ENST00000264376(transcript)|ensembl:ENST00000644920(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005212"(structural constituent of eye lens)|interpro:IPR001064(Beta and gamma crystallin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007601"(visual perception)|go:"GO:0034614"(cellular response to reactive oxygen species)|interpro:IPR011024(Gamma-crystallin related)|rcsb pdb:1H4A|rcsb pdb:1HK0|rcsb pdb:1LD0|rcsb pdb:2G98|rcsb pdb:2KFB|rcsb pdb:2KLJ|rcsb pdb:4GR7|rcsb pdb:4JGF|rcsb pdb:6ETA|rcsb pdb:6ETC|rcsb pdb:6W5B|rcsb pdb:6WCY|refseq:NP_008822.2|dip:DIP-46208N|mint:MINT-8303081(identity) go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007601"(visual perception)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010288"(response to lead ion)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|ensembl:ENSRNOG00000047175(gene)|ensembl:ENSRNOT00000075545(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0070141"(response to UV-A)|go:"GO:0070309"(lens fiber cell morphogenesis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR012274(Alpha-crystallin, subunit A)|go:"GO:0046872"(metal ion binding)|rgd:2413|refseq:NP_036666.2|refseq:NP_001276666.1|mint:MINT-8303087(identity) - comment:mint|comment:homomint comment:mint figure legend:f4a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:43.0x10^-6(molar) 2012/01/13 2014/10/16 rogid:qU4whgmCS9+Zq9udbDIhSLFLV0s9606 rogid:VRK116L/kz6hQZKms/qSNi+iVhw10116 intact-crc:3AB5353F38271B97|rigid:KcjqGj/quN1F8k96RNf72aJhckw false mutation increasing interaction:76-76(MINT-8303084)|mutation increasing interaction:4-4(MINT-8303082) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07320 uniprotkb:P23927 intact:EBI-7673124|ensembl:ENSP00000264376|ensembl:ENSP00000496652|uniprotkb:Q53R51|intact:MINT-8303016|uniprotkb:Q17RF7|uniprotkb:Q99681 intact:EBI-299046|ensembl:ENSMUSP00000034562|ensembl:ENSMUSP00000149759|ensembl:ENSMUSP00000149803|ensembl:ENSMUSP00000150669|uniprotkb:Q64325 psi-mi:crgd_human(display_long)|uniprotkb:Gamma-crystallin 4(gene name synonym)|uniprotkb:CRYGD(gene name)|psi-mi:CRYGD(display_short)|uniprotkb:CRYG4(gene name synonym)|uniprotkb:Gamma-D-crystallin(gene name synonym) psi-mi:cryab_mouse(display_long)|uniprotkb:Cryab(gene name)|psi-mi:Cryab(display_short)|uniprotkb:Crya2(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:P23(gene name synonym) psi-mi:"MI:0051"(fluorescence technology) Mishra et al. (2012) pubmed:22289178|imex:IM-16817|mint:MINT-8303011|mint:d-11-02016 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7673407|mint:MINT-8303102|imex:IM-16817-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0070306"(lens fiber cell differentiation)|ensembl:ENSG00000118231(gene)|ensembl:ENSG00000285434(gene)|ensembl:ENST00000264376(transcript)|ensembl:ENST00000644920(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005212"(structural constituent of eye lens)|interpro:IPR001064(Beta and gamma crystallin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007601"(visual perception)|go:"GO:0034614"(cellular response to reactive oxygen species)|interpro:IPR011024(Gamma-crystallin related)|rcsb pdb:1H4A|rcsb pdb:1HK0|rcsb pdb:1LD0|rcsb pdb:2G98|rcsb pdb:2KFB|rcsb pdb:2KLJ|rcsb pdb:4GR7|rcsb pdb:4JGF|rcsb pdb:6ETA|rcsb pdb:6ETC|rcsb pdb:6W5B|rcsb pdb:6WCY|refseq:NP_008822.2|dip:DIP-46208N|mint:MINT-8303104(identity) ensembl:ENSMUSG00000032060(gene)|ensembl:ENSMUST00000034562(transcript)|ensembl:ENSMUST00000214962(transcript)|ensembl:ENSMUST00000216755(transcript)|ensembl:ENSMUST00000217475(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043292"(contractile fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P23927|reactome:R-MMU-3371571|refseq:XP_006510033.1|refseq:NP_034094.1|refseq:NP_001276711.1|refseq:NP_001276713.1|refseq:NP_001276714.1|dip:DIP-31060N|mint:MINT-8303110(identity) - comment:mint|comment:homomint - figure legend:f4b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:27.0x10^-6(molar) 2012/01/13 2014/10/16 rogid:qU4whgmCS9+Zq9udbDIhSLFLV0s9606 rogid:LOp5smbeRceV8/P+Eaoh7p+24Vw10090 intact-crc:B58A5CC33B71EC3D|rigid:w3i8VC77M2pnh2P5xCzDiGZ5Afc false mutation increasing interaction:76-76(MINT-8303105)|mutation increasing interaction:4-4(MINT-8303107) mutation increasing interaction:45-45(MINT-8303113)|mutation increasing interaction:59-59(MINT-8303111)|mutation increasing interaction:19-19(MINT-8303115) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)