#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:E7EM37	uniprotkb:Q9BIG2	intact:EBI-6082999|uniprotkb:A0A486WWQ7|uniprotkb:A0A486WXI1|uniprotkb:A0A486WYH7|uniprotkb:G5EBI6|uniprotkb:G5EEM7|uniprotkb:H2L2G2|ensemblmetazoa:K09G1.4b.1|ensemblmetazoa:K09G1.4c.1	intact:EBI-2923711|ensemblmetazoa:B0207.3b.1|uniprotkb:Q7Z117|uniprotkb:O01428	psi-mi:dopr2_caeel(display_long)|uniprotkb:Dopamine D2-like receptor dop-2(gene name synonym)|uniprotkb:dop-2(gene name)|psi-mi:dop-2(display_short)|uniprotkb:K09G1.4(orf name)|uniprotkb:dop-2L(gene name synonym)	psi-mi:gpa14_caeel(display_long)|uniprotkb:gpa-14(gene name)|psi-mi:gpa-14(display_short)|uniprotkb:B0207.3(orf name)	psi-mi:"MI:0112"(ubiquitin reconstruction)	Pandey et al. (2012)	pubmed:22280843|imex:IM-17190	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1263"(Molecular Connections)	intact:EBI-5650955|imex:IM-17190-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	wormbase:K09G1.4c|ensemblmetazoa:WBGene00001053(gene)|reactome:R-CEL-390651|reactome:R-CEL-390666|reactome:R-CEL-418594|refseq:NP_001256126.1|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|wormbase:K09G1.4a|wormbase:K09G1.4d|wormbase:K09G1.4e|wormbase:K09G1.4f|wormbase:K09G1.4g|refseq:NP_001024047.1|refseq:NP_001256127.1|refseq:NP_001024048.1|ensemblmetazoa:K09G1.4b.1(transcript)|ensemblmetazoa:K09G1.4c.1(transcript)|ensemblmetazoa:WBGene00001053(gene)|ensemblmetazoa:WBGene00001053(gene)|go:"GO:0001591"(dopamine neurotransmitter receptor activity, coupled via Gi/Go)|go:"GO:0004993"(G protein-coupled serotonin receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032094"(response to food)|go:"GO:0033602"(negative regulation of dopamine secretion)|go:"GO:0034608"(vulval location)|go:"GO:0034609"(spicule insertion)|go:"GO:0045202"(synapse)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071419"(cellular response to amphetamine)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0090327"(negative regulation of locomotion involved in locomotory behavior)|go:"GO:1902435"(regulation of male mating behavior)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902847"(regulation of neuronal signal transduction)	ensemblmetazoa:B0207.3b.1(transcript)|ensemblmetazoa:WBGene00001676(gene)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR027417|refseq:NP_001020965.1|refseq:NP_001020966.2|wormbase:B0207.3a|wormbase:B0207.3b|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|reactome:R-CEL-170670|reactome:R-CEL-2485179|reactome:R-CEL-2514859|reactome:R-CEL-392170|reactome:R-CEL-4086398|reactome:R-CEL-418594|reactome:R-CEL-418597	-	-	-	figure legend:fig. 2a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2012/02/27	2014/10/16	rogid:W/go554sja8ENCPSvDHiS+i6mVw6239	rogid:YYyGHVPWLF95kMEUJ+k31iQSyJA6239	intact-crc:2E40AF75BA8F1297|rigid:uAuX+UOnMyjbu4dQnlPaCaCNDwI	false	tag:?-?	tag:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9BIG2	uniprotkb:E7EM37	intact:EBI-2923711|ensemblmetazoa:B0207.3b.1|uniprotkb:Q7Z117|uniprotkb:O01428	intact:EBI-6082999|uniprotkb:A0A486WWQ7|uniprotkb:A0A486WXI1|uniprotkb:A0A486WYH7|uniprotkb:G5EBI6|uniprotkb:G5EEM7|uniprotkb:H2L2G2|ensemblmetazoa:K09G1.4b.1|ensemblmetazoa:K09G1.4c.1	psi-mi:gpa14_caeel(display_long)|uniprotkb:gpa-14(gene name)|psi-mi:gpa-14(display_short)|uniprotkb:B0207.3(orf name)	psi-mi:dopr2_caeel(display_long)|uniprotkb:Dopamine D2-like receptor dop-2(gene name synonym)|uniprotkb:dop-2(gene name)|psi-mi:dop-2(display_short)|uniprotkb:K09G1.4(orf name)|uniprotkb:dop-2L(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pandey et al. (2012)	pubmed:22280843|imex:IM-17190	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1263"(Molecular Connections)	intact:EBI-5651026|imex:IM-17190-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:B0207.3b.1(transcript)|ensemblmetazoa:WBGene00001676(gene)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR027417|refseq:NP_001020965.1|refseq:NP_001020966.2|wormbase:B0207.3a|wormbase:B0207.3b|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|reactome:R-CEL-170670|reactome:R-CEL-2485179|reactome:R-CEL-2514859|reactome:R-CEL-392170|reactome:R-CEL-4086398|reactome:R-CEL-418594|reactome:R-CEL-418597	wormbase:K09G1.4c|ensemblmetazoa:WBGene00001053(gene)|reactome:R-CEL-390651|reactome:R-CEL-390666|reactome:R-CEL-418594|refseq:NP_001256126.1|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|wormbase:K09G1.4a|wormbase:K09G1.4d|wormbase:K09G1.4e|wormbase:K09G1.4f|wormbase:K09G1.4g|refseq:NP_001024047.1|refseq:NP_001256127.1|refseq:NP_001024048.1|ensemblmetazoa:K09G1.4b.1(transcript)|ensemblmetazoa:K09G1.4c.1(transcript)|ensemblmetazoa:WBGene00001053(gene)|ensemblmetazoa:WBGene00001053(gene)|go:"GO:0001591"(dopamine neurotransmitter receptor activity, coupled via Gi/Go)|go:"GO:0004993"(G protein-coupled serotonin receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032094"(response to food)|go:"GO:0033602"(negative regulation of dopamine secretion)|go:"GO:0034608"(vulval location)|go:"GO:0034609"(spicule insertion)|go:"GO:0045202"(synapse)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071419"(cellular response to amphetamine)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0090327"(negative regulation of locomotion involved in locomotory behavior)|go:"GO:1902435"(regulation of male mating behavior)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902847"(regulation of neuronal signal transduction)	-	-	-	figure legend:fig. 2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/02/27	2014/10/16	rogid:YYyGHVPWLF95kMEUJ+k31iQSyJA6239	rogid:W/go554sja8ENCPSvDHiS+i6mVw6239	intact-crc:165F0D38153A0EAB|rigid:uAuX+UOnMyjbu4dQnlPaCaCNDwI	false	glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:E7EM37	uniprotkb:Q9BIG2	intact:EBI-6082999|uniprotkb:A0A486WWQ7|uniprotkb:A0A486WXI1|uniprotkb:A0A486WYH7|uniprotkb:G5EBI6|uniprotkb:G5EEM7|uniprotkb:H2L2G2|ensemblmetazoa:K09G1.4b.1|ensemblmetazoa:K09G1.4c.1	intact:EBI-2923711|ensemblmetazoa:B0207.3b.1|uniprotkb:Q7Z117|uniprotkb:O01428	psi-mi:dopr2_caeel(display_long)|uniprotkb:Dopamine D2-like receptor dop-2(gene name synonym)|uniprotkb:dop-2(gene name)|psi-mi:dop-2(display_short)|uniprotkb:K09G1.4(orf name)|uniprotkb:dop-2L(gene name synonym)	psi-mi:gpa14_caeel(display_long)|uniprotkb:gpa-14(gene name)|psi-mi:gpa-14(display_short)|uniprotkb:B0207.3(orf name)	psi-mi:"MI:0096"(pull down)	Pandey et al. (2012)	pubmed:22280843|imex:IM-17190	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:1263"(Molecular Connections)	intact:EBI-5651045|imex:IM-17190-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	wormbase:K09G1.4c|ensemblmetazoa:WBGene00001053(gene)|reactome:R-CEL-390651|reactome:R-CEL-390666|reactome:R-CEL-418594|refseq:NP_001256126.1|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|wormbase:K09G1.4a|wormbase:K09G1.4d|wormbase:K09G1.4e|wormbase:K09G1.4f|wormbase:K09G1.4g|refseq:NP_001024047.1|refseq:NP_001256127.1|refseq:NP_001024048.1|ensemblmetazoa:K09G1.4b.1(transcript)|ensemblmetazoa:K09G1.4c.1(transcript)|ensemblmetazoa:WBGene00001053(gene)|ensemblmetazoa:WBGene00001053(gene)|go:"GO:0001591"(dopamine neurotransmitter receptor activity, coupled via Gi/Go)|go:"GO:0004993"(G protein-coupled serotonin receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032094"(response to food)|go:"GO:0033602"(negative regulation of dopamine secretion)|go:"GO:0034608"(vulval location)|go:"GO:0034609"(spicule insertion)|go:"GO:0045202"(synapse)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071419"(cellular response to amphetamine)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0090327"(negative regulation of locomotion involved in locomotory behavior)|go:"GO:1902435"(regulation of male mating behavior)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902847"(regulation of neuronal signal transduction)	ensemblmetazoa:B0207.3b.1(transcript)|ensemblmetazoa:WBGene00001676(gene)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR027417|refseq:NP_001020965.1|refseq:NP_001020966.2|wormbase:B0207.3a|wormbase:B0207.3b|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|reactome:R-CEL-170670|reactome:R-CEL-2485179|reactome:R-CEL-2514859|reactome:R-CEL-392170|reactome:R-CEL-4086398|reactome:R-CEL-418594|reactome:R-CEL-418597	-	-	-	figure legend:fig. 4c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/02/27	2014/10/16	rogid:W/go554sja8ENCPSvDHiS+i6mVw6239	rogid:YYyGHVPWLF95kMEUJ+k31iQSyJA6239	intact-crc:49E517E89FBC727D|rigid:uAuX+UOnMyjbu4dQnlPaCaCNDwI	false	sufficient binding region:183-849	his tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:E7EM37	uniprotkb:Q9BIG2	intact:EBI-6082999|uniprotkb:A0A486WWQ7|uniprotkb:A0A486WXI1|uniprotkb:A0A486WYH7|uniprotkb:G5EBI6|uniprotkb:G5EEM7|uniprotkb:H2L2G2|ensemblmetazoa:K09G1.4b.1|ensemblmetazoa:K09G1.4c.1	intact:EBI-2923711|ensemblmetazoa:B0207.3b.1|uniprotkb:Q7Z117|uniprotkb:O01428	psi-mi:dopr2_caeel(display_long)|uniprotkb:Dopamine D2-like receptor dop-2(gene name synonym)|uniprotkb:dop-2(gene name)|psi-mi:dop-2(display_short)|uniprotkb:K09G1.4(orf name)|uniprotkb:dop-2L(gene name synonym)	psi-mi:gpa14_caeel(display_long)|uniprotkb:gpa-14(gene name)|psi-mi:gpa-14(display_short)|uniprotkb:B0207.3(orf name)	psi-mi:"MI:0018"(two hybrid)	Pandey et al. (2012)	pubmed:22280843|imex:IM-17190	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:1263"(Molecular Connections)	intact:EBI-6083829|imex:IM-17190-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	wormbase:K09G1.4c|ensemblmetazoa:WBGene00001053(gene)|reactome:R-CEL-390651|reactome:R-CEL-390666|reactome:R-CEL-418594|refseq:NP_001256126.1|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|wormbase:K09G1.4a|wormbase:K09G1.4d|wormbase:K09G1.4e|wormbase:K09G1.4f|wormbase:K09G1.4g|refseq:NP_001024047.1|refseq:NP_001256127.1|refseq:NP_001024048.1|ensemblmetazoa:K09G1.4b.1(transcript)|ensemblmetazoa:K09G1.4c.1(transcript)|ensemblmetazoa:WBGene00001053(gene)|ensemblmetazoa:WBGene00001053(gene)|go:"GO:0001591"(dopamine neurotransmitter receptor activity, coupled via Gi/Go)|go:"GO:0004993"(G protein-coupled serotonin receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032094"(response to food)|go:"GO:0033602"(negative regulation of dopamine secretion)|go:"GO:0034608"(vulval location)|go:"GO:0034609"(spicule insertion)|go:"GO:0045202"(synapse)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071419"(cellular response to amphetamine)|go:"GO:0090326"(positive regulation of locomotion involved in locomotory behavior)|go:"GO:0090327"(negative regulation of locomotion involved in locomotory behavior)|go:"GO:1902435"(regulation of male mating behavior)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1902847"(regulation of neuronal signal transduction)	ensemblmetazoa:B0207.3b.1(transcript)|ensemblmetazoa:WBGene00001676(gene)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR027417|refseq:NP_001020965.1|refseq:NP_001020966.2|wormbase:B0207.3a|wormbase:B0207.3b|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|reactome:R-CEL-170670|reactome:R-CEL-2485179|reactome:R-CEL-2514859|reactome:R-CEL-392170|reactome:R-CEL-4086398|reactome:R-CEL-418594|reactome:R-CEL-418597	-	-	-	figure legend:fig. 4b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2012/02/27	2014/10/16	rogid:W/go554sja8ENCPSvDHiS+i6mVw6239	rogid:YYyGHVPWLF95kMEUJ+k31iQSyJA6239	intact-crc:7A0739A93110CC79|rigid:uAuX+UOnMyjbu4dQnlPaCaCNDwI	false	necessary binding region:224-766	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)