#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O18195	uniprotkb:O01901	intact:EBI-313368|ensemblmetazoa:Y48E1B.1.1	intact:EBI-323542|ensemblmetazoa:F59E12.10.1	psi-mi:wash1_caeel(display_long)|uniprotkb:ddl-2(gene name)|psi-mi:ddl-2(display_short)|uniprotkb:Y48E1B.1(orf name)	psi-mi:wasc3_caeel(display_long)|uniprotkb:F59E12.10(orf name)|uniprotkb:ddl-1(gene name)|psi-mi:ddl-1(display_short)|uniprotkb:Daf-16-dependent longevity protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chiang et al. (2012)	pubmed:22265419|imex:IM-16614	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5395698|imex:IM-16614-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_496847.1|wormbase:Y48E1B.1|ensemblmetazoa:WBGene00013000(gene)|ensemblmetazoa:Y48E1B.1.1(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0071203"(WASH complex)|go:"GO:2000677"(regulation of transcription regulatory region DNA binding)|interpro:IPR021854|interpro:IPR028290|go:"GO:0043014"(alpha-tubulin binding)|dip:DIP-26697N	refseq:NP_495101.1|wormbase:F59E12.10|ensemblmetazoa:F59E12.10.1(transcript)|ensemblmetazoa:WBGene00019125(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0071203"(WASH complex)|go:"GO:2000677"(regulation of transcription regulatory region DNA binding)|interpro:IPR019309|dip:DIP-24590N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 4A, Supp. Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/01/31	2014/10/16	rogid:RJW5nUP6L8QcEdUDeGl4awDNlZU6239	rogid:eaFnu18EmUYozhoS5U6SILuvsVw6239	intact-crc:8F768DEEB4E8F9B4|rigid:kt6R7vTZBsxSc+JFN8uFpbMUQy0	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:G5EFT5	uniprotkb:O01901	intact:EBI-2916699|ensemblmetazoa:Y53C10A.12.1|intact:EBI-6780708|uniprotkb:Q6Q4G5	intact:EBI-323542|ensemblmetazoa:F59E12.10.1	psi-mi:hsf1_caeel(display_long)|uniprotkb:hsf-1(gene name)|psi-mi:hsf-1(display_short)|uniprotkb:Y53C10A.12(orf name)	psi-mi:wasc3_caeel(display_long)|uniprotkb:F59E12.10(orf name)|uniprotkb:ddl-1(gene name)|psi-mi:ddl-1(display_short)|uniprotkb:Daf-16-dependent longevity protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chiang et al. (2012)	pubmed:22265419|imex:IM-16614	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5395815|imex:IM-16614-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:WBGene00002004(gene)|ensemblmetazoa:Y53C10A.12.1(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0002119"(nematode larval development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009408"(response to heat)|go:"GO:0035966"(response to topologically incorrect protein)|go:"GO:0040024"(dauer larval development)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR027725|interpro:IPR000232("Heat shock factor (HSF)-type, DNA-binding")|reactome:R-CEL-3371453|reactome:R-CEL-3371511|reactome:R-CEL-3371568|reactome:R-CEL-3371571|refseq:NP_493031.1|wormbase:Y53C10A.12|interpro:IPR036388|interpro:IPR036390	refseq:NP_495101.1|wormbase:F59E12.10|ensemblmetazoa:F59E12.10.1(transcript)|ensemblmetazoa:WBGene00019125(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0071203"(WASH complex)|go:"GO:2000677"(regulation of transcription regulatory region DNA binding)|interpro:IPR019309|dip:DIP-24590N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 4C, 5D, SUpp. Fig. 4C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/01/31	2021/11/30	rogid:vjpAwwqoojERt/jHMBdH0+XCzGc6239	rogid:eaFnu18EmUYozhoS5U6SILuvsVw6239	intact-crc:9E627180354379CE|rigid:bZ4I4pHRjb3ZnqvziSr+9DXH2p0	false	myc tag:?-?	ha tag:?-?|mutation increasing interaction:182-182	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O18195	uniprotkb:O01901	intact:EBI-313368|ensemblmetazoa:Y48E1B.1.1	intact:EBI-323542|ensemblmetazoa:F59E12.10.1	psi-mi:wash1_caeel(display_long)|uniprotkb:ddl-2(gene name)|psi-mi:ddl-2(display_short)|uniprotkb:Y48E1B.1(orf name)	psi-mi:wasc3_caeel(display_long)|uniprotkb:F59E12.10(orf name)|uniprotkb:ddl-1(gene name)|psi-mi:ddl-1(display_short)|uniprotkb:Daf-16-dependent longevity protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chiang et al. (2012)	pubmed:22265419|imex:IM-16614	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5395738|imex:IM-16614-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_496847.1|wormbase:Y48E1B.1|ensemblmetazoa:WBGene00013000(gene)|ensemblmetazoa:Y48E1B.1.1(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0071203"(WASH complex)|go:"GO:2000677"(regulation of transcription regulatory region DNA binding)|interpro:IPR021854|interpro:IPR028290|go:"GO:0043014"(alpha-tubulin binding)|dip:DIP-26697N	refseq:NP_495101.1|wormbase:F59E12.10|ensemblmetazoa:F59E12.10.1(transcript)|ensemblmetazoa:WBGene00019125(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0071203"(WASH complex)|go:"GO:2000677"(regulation of transcription regulatory region DNA binding)|interpro:IPR019309|dip:DIP-24590N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Figs. 4A, 4E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/01/31	2014/10/16	rogid:RJW5nUP6L8QcEdUDeGl4awDNlZU6239	rogid:eaFnu18EmUYozhoS5U6SILuvsVw6239	intact-crc:4912D0807640C738|rigid:kt6R7vTZBsxSc+JFN8uFpbMUQy0	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9U3B7	uniprotkb:O01901	intact:EBI-311898|ensemblmetazoa:K08E7.2.1|ensemblmetazoa:K08E7.2.2|ensemblmetazoa:K08E7.2.3|ensemblmetazoa:K08E7.2.4	intact:EBI-323542|ensemblmetazoa:F59E12.10.1	psi-mi:q9u3b7_caeel(display_long)|uniprotkb:hsb-1(gene name)|psi-mi:hsb-1(display_short)|uniprotkb:K08E7.2(orf name)|uniprotkb:CELE_K08E7.2(orf name)	psi-mi:wasc3_caeel(display_long)|uniprotkb:F59E12.10(orf name)|uniprotkb:ddl-1(gene name)|psi-mi:ddl-1(display_short)|uniprotkb:Daf-16-dependent longevity protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chiang et al. (2012)	pubmed:22265419|imex:IM-16614	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5395756|imex:IM-16614-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:K08E7.2.1(transcript)|ensemblmetazoa:K08E7.2.2(transcript)|ensemblmetazoa:K08E7.2.3(transcript)|ensemblmetazoa:K08E7.2.4(transcript)|ensemblmetazoa:WBGene00002002(gene)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR009643(Heat shock factor binding 1)|refseq:NP_502406.1|wormbase:K08E7.2|reactome:R-CEL-3371568|reactome:R-CEL-3371571|dip:DIP-24483N	refseq:NP_495101.1|wormbase:F59E12.10|ensemblmetazoa:F59E12.10.1(transcript)|ensemblmetazoa:WBGene00019125(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0071203"(WASH complex)|go:"GO:2000677"(regulation of transcription regulatory region DNA binding)|interpro:IPR019309|dip:DIP-24590N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/01/31	2014/10/16	rogid:yIvrExb0LzyMu2AR2+t+9zbxBkM6239	rogid:eaFnu18EmUYozhoS5U6SILuvsVw6239	intact-crc:DBD79200B25794A0|rigid:mlljGaROYt/VVAMeqzBnPb1feWU	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O01901	uniprotkb:Q9U3B7	intact:EBI-323542|ensemblmetazoa:F59E12.10.1	intact:EBI-311898|ensemblmetazoa:K08E7.2.1|ensemblmetazoa:K08E7.2.2|ensemblmetazoa:K08E7.2.3|ensemblmetazoa:K08E7.2.4	psi-mi:wasc3_caeel(display_long)|uniprotkb:F59E12.10(orf name)|uniprotkb:ddl-1(gene name)|psi-mi:ddl-1(display_short)|uniprotkb:Daf-16-dependent longevity protein 1(gene name synonym)	psi-mi:q9u3b7_caeel(display_long)|uniprotkb:hsb-1(gene name)|psi-mi:hsb-1(display_short)|uniprotkb:K08E7.2(orf name)|uniprotkb:CELE_K08E7.2(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chiang et al. (2012)	pubmed:22265419|imex:IM-16614	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5395748|imex:IM-16614-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_495101.1|wormbase:F59E12.10|ensemblmetazoa:F59E12.10.1(transcript)|ensemblmetazoa:WBGene00019125(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0071203"(WASH complex)|go:"GO:2000677"(regulation of transcription regulatory region DNA binding)|interpro:IPR019309|dip:DIP-24590N	ensemblmetazoa:K08E7.2.1(transcript)|ensemblmetazoa:K08E7.2.2(transcript)|ensemblmetazoa:K08E7.2.3(transcript)|ensemblmetazoa:K08E7.2.4(transcript)|ensemblmetazoa:WBGene00002002(gene)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR009643(Heat shock factor binding 1)|refseq:NP_502406.1|wormbase:K08E7.2|reactome:R-CEL-3371568|reactome:R-CEL-3371571|dip:DIP-24483N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/01/31	2014/10/16	rogid:eaFnu18EmUYozhoS5U6SILuvsVw6239	rogid:yIvrExb0LzyMu2AR2+t+9zbxBkM6239	intact-crc:386407B322742484|rigid:mlljGaROYt/VVAMeqzBnPb1feWU	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:G5EFT5	uniprotkb:O01901	intact:EBI-2916699|ensemblmetazoa:Y53C10A.12.1|intact:EBI-6780708|uniprotkb:Q6Q4G5	intact:EBI-323542|ensemblmetazoa:F59E12.10.1	psi-mi:hsf1_caeel(display_long)|uniprotkb:hsf-1(gene name)|psi-mi:hsf-1(display_short)|uniprotkb:Y53C10A.12(orf name)	psi-mi:wasc3_caeel(display_long)|uniprotkb:F59E12.10(orf name)|uniprotkb:ddl-1(gene name)|psi-mi:ddl-1(display_short)|uniprotkb:Daf-16-dependent longevity protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chiang et al. (2012)	pubmed:22265419|imex:IM-16614	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5395800|imex:IM-16614-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:WBGene00002004(gene)|ensemblmetazoa:Y53C10A.12.1(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0002119"(nematode larval development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009408"(response to heat)|go:"GO:0035966"(response to topologically incorrect protein)|go:"GO:0040024"(dauer larval development)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR027725|interpro:IPR000232("Heat shock factor (HSF)-type, DNA-binding")|reactome:R-CEL-3371453|reactome:R-CEL-3371511|reactome:R-CEL-3371568|reactome:R-CEL-3371571|refseq:NP_493031.1|wormbase:Y53C10A.12|interpro:IPR036388|interpro:IPR036390	refseq:NP_495101.1|wormbase:F59E12.10|ensemblmetazoa:F59E12.10.1(transcript)|ensemblmetazoa:WBGene00019125(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0071203"(WASH complex)|go:"GO:2000677"(regulation of transcription regulatory region DNA binding)|interpro:IPR019309|dip:DIP-24590N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 4C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2012/01/31	2021/11/30	rogid:vjpAwwqoojERt/jHMBdH0+XCzGc6239	rogid:eaFnu18EmUYozhoS5U6SILuvsVw6239	intact-crc:30437DD385898282|rigid:bZ4I4pHRjb3ZnqvziSr+9DXH2p0	false	myc tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:G5EFT5	uniprotkb:O01901	intact:EBI-2916699|ensemblmetazoa:Y53C10A.12.1|intact:EBI-6780708|uniprotkb:Q6Q4G5	intact:EBI-323542|ensemblmetazoa:F59E12.10.1	psi-mi:hsf1_caeel(display_long)|uniprotkb:hsf-1(gene name)|psi-mi:hsf-1(display_short)|uniprotkb:Y53C10A.12(orf name)	psi-mi:wasc3_caeel(display_long)|uniprotkb:F59E12.10(orf name)|uniprotkb:ddl-1(gene name)|psi-mi:ddl-1(display_short)|uniprotkb:Daf-16-dependent longevity protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chiang et al. (2012)	pubmed:22265419|imex:IM-16614	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5395911|imex:IM-16614-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:WBGene00002004(gene)|ensemblmetazoa:Y53C10A.12.1(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0002119"(nematode larval development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009408"(response to heat)|go:"GO:0035966"(response to topologically incorrect protein)|go:"GO:0040024"(dauer larval development)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR027725|interpro:IPR000232("Heat shock factor (HSF)-type, DNA-binding")|reactome:R-CEL-3371453|reactome:R-CEL-3371511|reactome:R-CEL-3371568|reactome:R-CEL-3371571|refseq:NP_493031.1|wormbase:Y53C10A.12|interpro:IPR036388|interpro:IPR036390	refseq:NP_495101.1|wormbase:F59E12.10|ensemblmetazoa:F59E12.10.1(transcript)|ensemblmetazoa:WBGene00019125(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0071203"(WASH complex)|go:"GO:2000677"(regulation of transcription regulatory region DNA binding)|interpro:IPR019309|dip:DIP-24590N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 4D, 5A, Supp. 4A|comment:Depletion of daf-2 or akt-1 decreased the interaction strength. Depletion of hsb-1prevents interaction from occuring.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2012/01/31	2021/11/30	rogid:vjpAwwqoojERt/jHMBdH0+XCzGc6239	rogid:eaFnu18EmUYozhoS5U6SILuvsVw6239	intact-crc:1995D57CBB297D4E|rigid:bZ4I4pHRjb3ZnqvziSr+9DXH2p0	false	-	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O01901	uniprotkb:O18195	intact:EBI-323542|ensemblmetazoa:F59E12.10.1	intact:EBI-313368|ensemblmetazoa:Y48E1B.1.1	psi-mi:wasc3_caeel(display_long)|uniprotkb:F59E12.10(orf name)|uniprotkb:ddl-1(gene name)|psi-mi:ddl-1(display_short)|uniprotkb:Daf-16-dependent longevity protein 1(gene name synonym)	psi-mi:wash1_caeel(display_long)|uniprotkb:ddl-2(gene name)|psi-mi:ddl-2(display_short)|uniprotkb:Y48E1B.1(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chiang et al. (2012)	pubmed:22265419|imex:IM-16614	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-5395985|imex:IM-16614-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_495101.1|wormbase:F59E12.10|ensemblmetazoa:F59E12.10.1(transcript)|ensemblmetazoa:WBGene00019125(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0071203"(WASH complex)|go:"GO:2000677"(regulation of transcription regulatory region DNA binding)|interpro:IPR019309|dip:DIP-24590N	refseq:NP_496847.1|wormbase:Y48E1B.1|ensemblmetazoa:WBGene00013000(gene)|ensemblmetazoa:Y48E1B.1.1(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0071203"(WASH complex)|go:"GO:2000677"(regulation of transcription regulatory region DNA binding)|interpro:IPR021854|interpro:IPR028290|go:"GO:0043014"(alpha-tubulin binding)|dip:DIP-26697N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 4E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2012/01/31	2014/10/16	rogid:eaFnu18EmUYozhoS5U6SILuvsVw6239	rogid:RJW5nUP6L8QcEdUDeGl4awDNlZU6239	intact-crc:1CEBDF3A284D6F5E|rigid:kt6R7vTZBsxSc+JFN8uFpbMUQy0	false	ha tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0707"(anti tag immunostaining)