#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P28481	uniprotkb:P28481	intact:EBI-738477|uniprotkb:Q61428|uniprotkb:Q62031|uniprotkb:Q62032|uniprotkb:Q62033|uniprotkb:Q641K3|uniprotkb:Q6LDB1|uniprotkb:Q6LDI8|uniprotkb:Q6LDI9|uniprotkb:Q80VY3|uniprotkb:Q80X38|uniprotkb:Q8CEF7|uniprotkb:Q8K0N6|ensembl:ENSMUSP00000023123	intact:EBI-738477|uniprotkb:Q61428|uniprotkb:Q62031|uniprotkb:Q62032|uniprotkb:Q62033|uniprotkb:Q641K3|uniprotkb:Q6LDB1|uniprotkb:Q6LDI8|uniprotkb:Q6LDI9|uniprotkb:Q80VY3|uniprotkb:Q80X38|uniprotkb:Q8CEF7|uniprotkb:Q8K0N6|ensembl:ENSMUSP00000023123	psi-mi:co2a1_mouse(display_long)|uniprotkb:Col2a1(gene name)|psi-mi:Col2a1(display_short)|uniprotkb:Alpha-1 type II collagen(gene name synonym)	psi-mi:co2a1_mouse(display_long)|uniprotkb:Col2a1(gene name)|psi-mi:Col2a1(display_short)|uniprotkb:Alpha-1 type II collagen(gene name synonym)	psi-mi:"MI:0808"(comigration in sds page)	Lewis et al. (2012)	pubmed:22248926|imex:IM-17885	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:1126"(self interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-6256942|imex:IM-17885-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001106987.2|refseq:NP_112440.2|ensembl:ENSMUSG00000022483(gene)|ensembl:ENSMUST00000023123(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001503"(ossification)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005581"(collagen trimer)|go:"GO:0005585"(collagen type II trimer)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006029"(proteoglycan metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030903"(notochord development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0051216"(cartilage development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060174"(limb bud formation)|go:"GO:0060272"(embryonic skeletal joint morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071599"(otic vesicle development)|go:"GO:0097065"(anterior head development)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR008160(Collagen triple helix repeat)|rcsb pdb:2W65|rcsb pdb:4BKL|rcsb pdb:5MU0|rcsb pdb:5MUB|go:"GO:0071773"(cellular response to BMP stimulus)|rcsb pdb:5MV3|rcsb pdb:5MV4|reactome:R-MMU-1442490|reactome:R-MMU-1474244|reactome:R-MMU-1650814|reactome:R-MMU-186797|reactome:R-MMU-198933|reactome:R-MMU-2022090|reactome:R-MMU-216083|reactome:R-MMU-3000171|reactome:R-MMU-3000178|reactome:R-MMU-419037|reactome:R-MMU-8874081|reactome:R-MMU-8948216	refseq:NP_001106987.2|refseq:NP_112440.2|ensembl:ENSMUSG00000022483(gene)|ensembl:ENSMUST00000023123(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001503"(ossification)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005581"(collagen trimer)|go:"GO:0005585"(collagen type II trimer)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006029"(proteoglycan metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030903"(notochord development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0051216"(cartilage development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060174"(limb bud formation)|go:"GO:0060272"(embryonic skeletal joint morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071599"(otic vesicle development)|go:"GO:0097065"(anterior head development)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR008160(Collagen triple helix repeat)|rcsb pdb:2W65|rcsb pdb:4BKL|rcsb pdb:5MU0|rcsb pdb:5MUB|go:"GO:0071773"(cellular response to BMP stimulus)|rcsb pdb:5MV3|rcsb pdb:5MV4|reactome:R-MMU-1442490|reactome:R-MMU-1474244|reactome:R-MMU-1650814|reactome:R-MMU-186797|reactome:R-MMU-198933|reactome:R-MMU-2022090|reactome:R-MMU-216083|reactome:R-MMU-3000171|reactome:R-MMU-3000178|reactome:R-MMU-419037|reactome:R-MMU-8874081|reactome:R-MMU-8948216	-	-	-	figure legend:8A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-cartliage)|taxid:10090(mouse cartliage)	-	2012/07/29	2014/10/16	rogid:BvMsaSq1M7VaA+9duIrCixXrZwo10090	rogid:BvMsaSq1M7VaA+9duIrCixXrZwo10090	intact-crc:07432C29EB4F70EF|rigid:OlBsja9LL9nBFJIl3Md4n6MxxL8	false	-	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P28481	uniprotkb:P28481	intact:EBI-738477|uniprotkb:Q61428|uniprotkb:Q62031|uniprotkb:Q62032|uniprotkb:Q62033|uniprotkb:Q641K3|uniprotkb:Q6LDB1|uniprotkb:Q6LDI8|uniprotkb:Q6LDI9|uniprotkb:Q80VY3|uniprotkb:Q80X38|uniprotkb:Q8CEF7|uniprotkb:Q8K0N6|ensembl:ENSMUSP00000023123	intact:EBI-738477|uniprotkb:Q61428|uniprotkb:Q62031|uniprotkb:Q62032|uniprotkb:Q62033|uniprotkb:Q641K3|uniprotkb:Q6LDB1|uniprotkb:Q6LDI8|uniprotkb:Q6LDI9|uniprotkb:Q80VY3|uniprotkb:Q80X38|uniprotkb:Q8CEF7|uniprotkb:Q8K0N6|ensembl:ENSMUSP00000023123	psi-mi:co2a1_mouse(display_long)|uniprotkb:Col2a1(gene name)|psi-mi:Col2a1(display_short)|uniprotkb:Alpha-1 type II collagen(gene name synonym)	psi-mi:co2a1_mouse(display_long)|uniprotkb:Col2a1(gene name)|psi-mi:Col2a1(display_short)|uniprotkb:Alpha-1 type II collagen(gene name synonym)	psi-mi:"MI:0808"(comigration in sds page)	Lewis et al. (2012)	pubmed:22248926|imex:IM-17885	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:1126"(self interaction)	psi-mi:"MI:0917"(matrixdb)	intact:EBI-6256953|imex:IM-17885-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0898"(putative self)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001106987.2|refseq:NP_112440.2|ensembl:ENSMUSG00000022483(gene)|ensembl:ENSMUST00000023123(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001503"(ossification)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005581"(collagen trimer)|go:"GO:0005585"(collagen type II trimer)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006029"(proteoglycan metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030903"(notochord development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0051216"(cartilage development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060174"(limb bud formation)|go:"GO:0060272"(embryonic skeletal joint morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071599"(otic vesicle development)|go:"GO:0097065"(anterior head development)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR008160(Collagen triple helix repeat)|rcsb pdb:2W65|rcsb pdb:4BKL|rcsb pdb:5MU0|rcsb pdb:5MUB|go:"GO:0071773"(cellular response to BMP stimulus)|rcsb pdb:5MV3|rcsb pdb:5MV4|reactome:R-MMU-1442490|reactome:R-MMU-1474244|reactome:R-MMU-1650814|reactome:R-MMU-186797|reactome:R-MMU-198933|reactome:R-MMU-2022090|reactome:R-MMU-216083|reactome:R-MMU-3000171|reactome:R-MMU-3000178|reactome:R-MMU-419037|reactome:R-MMU-8874081|reactome:R-MMU-8948216	refseq:NP_001106987.2|refseq:NP_112440.2|ensembl:ENSMUSG00000022483(gene)|ensembl:ENSMUST00000023123(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001503"(ossification)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005581"(collagen trimer)|go:"GO:0005585"(collagen type II trimer)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006029"(proteoglycan metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030903"(notochord development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048839"(inner ear development)|go:"GO:0051216"(cartilage development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060174"(limb bud formation)|go:"GO:0060272"(embryonic skeletal joint morphogenesis)|go:"GO:0060348"(bone development)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071599"(otic vesicle development)|go:"GO:0097065"(anterior head development)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR008160(Collagen triple helix repeat)|rcsb pdb:2W65|rcsb pdb:4BKL|rcsb pdb:5MU0|rcsb pdb:5MUB|go:"GO:0071773"(cellular response to BMP stimulus)|rcsb pdb:5MV3|rcsb pdb:5MV4|reactome:R-MMU-1442490|reactome:R-MMU-1474244|reactome:R-MMU-1650814|reactome:R-MMU-186797|reactome:R-MMU-198933|reactome:R-MMU-2022090|reactome:R-MMU-216083|reactome:R-MMU-3000171|reactome:R-MMU-3000178|reactome:R-MMU-419037|reactome:R-MMU-8874081|reactome:R-MMU-8948216	-	-	-	figure legend:8B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-cartliage)|taxid:10090(mouse cartliage)	-	2012/07/29	2014/10/16	rogid:BvMsaSq1M7VaA+9duIrCixXrZwo10090	rogid:BvMsaSq1M7VaA+9duIrCixXrZwo10090	intact-crc:2E65F29E38CCF69D|rigid:OlBsja9LL9nBFJIl3Md4n6MxxL8	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)