#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O60235	uniprotkb:P26927	intact:EBI-7639969|ensembl:ENSP00000283916|intact:MINT-8302106|uniprotkb:Q08AF6	intact:EBI-6929133|uniprotkb:Q6GTN4|uniprotkb:A8MSX3|uniprotkb:Q14870|uniprotkb:Q13350|uniprotkb:A6NLA3	psi-mi:tm11d_human(display_long)|uniprotkb:TMPRSS11D(gene name)|psi-mi:TMPRSS11D(display_short)|uniprotkb:Airway trypsin-like protease(gene name synonym)|uniprotkb:HAT(gene name synonym)	psi-mi:hgfl_human(display_long)|uniprotkb:D3F15S2(gene name synonym)|uniprotkb:DNF15S2(gene name synonym)|uniprotkb:HGFL(gene name synonym)|uniprotkb:Macrophage stimulatory protein(gene name synonym)|uniprotkb:Macrophage-stimulating protein(gene name synonym)|uniprotkb:MST1(gene name)|psi-mi:MST1(display_short)	psi-mi:"MI:0435"(protease assay)	Orikawa et al. (2012)	pubmed:22245154|imex:IM-16811|mint:MINT-8302077|doi:10.1016/j.febslet.2012.01.009	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0194"(cleavage reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7639963|mint:MINT-8302112|imex:IM-16811-1	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000153802(gene)|ensembl:ENST00000283916(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008233"(peptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000082(SEA)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR017329(Transmembrane serine proteases, TMPRSS11A)|interpro:IPR018114|interpro:IPR033116|interpro:IPR036364|interpro:IPR043504|refseq:NP_004253.1|mint:MINT-8302118(identity)|uniprotkb:O60235(original identifier)	go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0010758"(regulation of macrophage chemotaxis)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:2000479"(regulation of cAMP-dependent protein kinase activity)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR024174|interpro:IPR038178|interpro:IPR043504|interpro:IPR043575|rcsb pdb:2ASU|rcsb pdb:4QT8|reactome:R-HSA-8852405|refseq:NP_066278.3|mint:P26927|dip:DIP-6028N|mint:MINT-8302113(identity)|uniprotkb:P26927(original identifier)	-	comment:mint|comment:homomint	-	figure legend:F1|comment:homomint|comment:mint|resulting-ptm:cleavage of P26927 at the arg483-val484 peptide bond|causality statement:O60235 is required for cleavage of P26927|causality statement:O60235 increases activity of P26927|causality statement:O60235 increases quantity of PRO_0000028086|causality statement:O60235 increases quantity of PRO_0000028087|comment:"Processing of HGFL/MST (P26927) by TM11D/HAT (O60235) was suppressed at higher sodium chloride (NaCl) concentrations (tested at 50, 150 and 200 millimolar NaCl)."|dataset:IBD - Inflammatory bowel disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/01/04	2014/10/24	rogid:xoYygedtCMOXPttieFmCKGE47RI9606	rogid:CdkibLlWSzABgjln1RQ0/wPVfTc9606	intact-crc:EE135841BF5BA075|rigid:Qf8T2JkwDV5Woh7lyS9SJmkyuaI	false	-	uncategorized protein modification:483-484(MINT-8302126)|his tag:c-c(MINT-8302116)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0039"(edman degradation)