#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9UL45 uniprotkb:P78537 intact:EBI-465781|ensembl:ENSP00000220531 intact:EBI-348630|uniprotkb:Q6NZ45|uniprotkb:A1L4Q9|ensembl:ENSP00000447537 psi-mi:bl1s6_human(display_long)|uniprotkb:BLOC1S6(gene name)|psi-mi:BLOC1S6(display_short)|uniprotkb:PA(gene name synonym)|uniprotkb:PLDN(gene name synonym)|uniprotkb:Pallid protein homolog(gene name synonym)|uniprotkb:Pallidin(gene name synonym)|uniprotkb:Syntaxin 13-interacting protein(gene name synonym) psi-mi:bl1s1_human(display_long)|uniprotkb:BLOC1S1(gene name)|psi-mi:BLOC1S1(display_short)|uniprotkb:BLOS1(gene name synonym)|uniprotkb:RT14(gene name synonym)|uniprotkb:GCN5L1(gene name synonym)|uniprotkb:GCN5-like protein 1(gene name synonym)|uniprotkb:Protein RT14(gene name synonym) psi-mi:"MI:0096"(pull down) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160137|imex:IM-17362-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000104164(gene)|ensembl:ENST00000220531(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032402"(melanosome transport)|go:"GO:0032438"(melanosome organization)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033299"(secretion of lysosomal enzymes)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050942"(positive regulation of pigment cell differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0098793"(presynapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR017242(BLOC-1 complex, pallidin subunit)|go:"GO:0031175"(neuron projection development)|interpro:IPR028119|mint:Q9UL45|reactome:R-HSA-432722|refseq:NP_036520.1 refseq:NP_001478.2|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR009395(GCN5-like 1)|mint:P78537|reactome:R-HSA-432720|reactome:R-HSA-432722|ensembl:ENSG00000135441(gene)|ensembl:ENST00000548925(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016197"(endosomal transport)|go:"GO:0018394"(peptidyl-lysine acetylation) - - - figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:s5/ikwpqtA8Mm8gMd6ttfmBBKSA9606 rogid:lntB3izez0HoFLPpiAtPBayt+G49606 intact-crc:8F0EFE7655C99FD5|rigid:eeKxmJ/jvTifnIkWg13ybEPnSZA false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9UL45 uniprotkb:Q9NUP1 intact:EBI-465781|ensembl:ENSP00000220531 intact:EBI-465852|uniprotkb:Q96G84|ensembl:ENSP00000318128|uniprotkb:Q6NVY6 psi-mi:bl1s6_human(display_long)|uniprotkb:BLOC1S6(gene name)|psi-mi:BLOC1S6(display_short)|uniprotkb:PA(gene name synonym)|uniprotkb:PLDN(gene name synonym)|uniprotkb:Pallid protein homolog(gene name synonym)|uniprotkb:Pallidin(gene name synonym)|uniprotkb:Syntaxin 13-interacting protein(gene name synonym) psi-mi:bl1s4_human(display_long)|uniprotkb:BLOC1S4(gene name)|psi-mi:BLOC1S4(display_short)|uniprotkb:CNO(gene name synonym)|uniprotkb:Protein cappuccino homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160137|imex:IM-17362-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000104164(gene)|ensembl:ENST00000220531(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032402"(melanosome transport)|go:"GO:0032438"(melanosome organization)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033299"(secretion of lysosomal enzymes)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050942"(positive regulation of pigment cell differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0098793"(presynapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR017242(BLOC-1 complex, pallidin subunit)|go:"GO:0031175"(neuron projection development)|interpro:IPR028119|mint:Q9UL45|reactome:R-HSA-432722|refseq:NP_036520.1 go:"GO:0008089"(anterograde axonal transport)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032438"(melanosome organization)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0070527"(platelet aggregation)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR024857|reactome:R-HSA-432722|ensembl:ENSG00000186222(gene)|ensembl:ENST00000320776(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_060836.1 - - - figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:s5/ikwpqtA8Mm8gMd6ttfmBBKSA9606 rogid:OGP3Nz9cdPa/BmzSDjUtdbg5XpE9606 intact-crc:8F0EFE7655C99FD5|rigid:eeKxmJ/jvTifnIkWg13ybEPnSZA false his tag:n-n sufficient binding region:1-177 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q6QNY1 uniprotkb:Q96EV8 intact:EBI-465872|ensembl:ENSP00000359398|uniprotkb:Q5W040|uniprotkb:Q8WUI8|uniprotkb:B4DQV2 intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3 psi-mi:bl1s2_human(display_long)|uniprotkb:BLOC1S2(gene name)|psi-mi:BLOC1S2(display_short)|uniprotkb:BLOS2(gene name synonym)|uniprotkb:CEAP(gene name synonym)|uniprotkb:Centrosome-associated protein(gene name synonym) psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym) psi-mi:"MI:0096"(pull down) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160166|imex:IM-17362-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016197"(endosomal transport)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|ensembl:ENSG00000196072(gene)|go:"GO:0032418"(lysosome localization)|ensembl:ENST00000370372(transcript)|go:"GO:0032438"(melanosome organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0005634"(nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR019269|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0008022"(protein C-terminus binding)|refseq:NP_776170.2|refseq:NP_001001342.1|refseq:NP_001269366.1|refseq:NP_001269367.1 ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1 - - - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:UFYvRoJEOtMQZa5OEOCt2gHLOm89606 rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606 intact-crc:A59720B4EE8FA479|rigid:psr7a21yxKQJlqRl+AoyXW8Z/K8 false - sufficient binding region:47-140|glutathione s tranferase tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q6QNY1 uniprotkb:O95295 intact:EBI-465872|ensembl:ENSP00000359398|uniprotkb:Q5W040|uniprotkb:Q8WUI8|uniprotkb:B4DQV2 intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56 psi-mi:bl1s2_human(display_long)|uniprotkb:BLOC1S2(gene name)|psi-mi:BLOC1S2(display_short)|uniprotkb:BLOS2(gene name synonym)|uniprotkb:CEAP(gene name synonym)|uniprotkb:Centrosome-associated protein(gene name synonym) psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym) psi-mi:"MI:0096"(pull down) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160166|imex:IM-17362-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016197"(endosomal transport)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|ensembl:ENSG00000196072(gene)|go:"GO:0032418"(lysosome localization)|ensembl:ENST00000370372(transcript)|go:"GO:0032438"(melanosome organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0005634"(nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR019269|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0008022"(protein C-terminus binding)|refseq:NP_776170.2|refseq:NP_001001342.1|refseq:NP_001269366.1|refseq:NP_001269367.1 ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1 - - - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:UFYvRoJEOtMQZa5OEOCt2gHLOm89606 rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606 intact-crc:A59720B4EE8FA479|rigid:psr7a21yxKQJlqRl+AoyXW8Z/K8 false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q96EV8 uniprotkb:Q9NUP1 intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3 intact:EBI-465852|uniprotkb:Q96G84|ensembl:ENSP00000318128|uniprotkb:Q6NVY6 psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym) psi-mi:bl1s4_human(display_long)|uniprotkb:BLOC1S4(gene name)|psi-mi:BLOC1S4(display_short)|uniprotkb:CNO(gene name synonym)|uniprotkb:Protein cappuccino homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159987|imex:IM-17362-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1 go:"GO:0008089"(anterograde axonal transport)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032438"(melanosome organization)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0070527"(platelet aggregation)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR024857|reactome:R-HSA-432722|ensembl:ENSG00000186222(gene)|ensembl:ENST00000320776(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_060836.1 - - - comment:All eight subunits of BLOC-1 were coexpressed from a single polycistronic plasmid in E. coli. Coomassie staining showed no Ecoli proteins to co-purify with the 8 proteins.|figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606 rogid:OGP3Nz9cdPa/BmzSDjUtdbg5XpE9606 intact-crc:20B59DA120D950DD|rigid:9qvtgS6jBZzKSiDLsBzBq2+3jOQ false sufficient binding region:1-217|glutathione s tranferase tag:c-c - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q96EV8 uniprotkb:Q8TDH9 intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3 intact:EBI-465861|ensembl:ENSP00000380598|uniprotkb:Q0VDJ7|uniprotkb:Q5THS1|uniprotkb:Q68D56|uniprotkb:Q8N5F9|uniprotkb:Q9NU16|uniprotkb:B4DVM2|uniprotkb:Q0VDJ6 psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym) psi-mi:bl1s5_human(display_long)|uniprotkb:BLOC1S5(gene name)|psi-mi:BLOC1S5(display_short)|uniprotkb:MUTED(gene name synonym)|uniprotkb:Protein Muted homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159987|imex:IM-17362-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1 ensembl:ENSG00000188428(gene)|ensembl:ENST00000397457(transcript)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032402"(melanosome transport)|go:"GO:0032438"(melanosome organization)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050942"(positive regulation of pigment cell differentiation)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR017243(BLOC-1 complex, muted subunit)|refseq:NP_958437.1|refseq:NP_001186251.1 - - - comment:All eight subunits of BLOC-1 were coexpressed from a single polycistronic plasmid in E. coli. Coomassie staining showed no Ecoli proteins to co-purify with the 8 proteins.|figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606 rogid:Bbv2N+NCAJ0baNXhhFYIsIqDwSg9606 intact-crc:20B59DA120D950DD|rigid:9qvtgS6jBZzKSiDLsBzBq2+3jOQ false sufficient binding region:1-217|glutathione s tranferase tag:c-c - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q96EV8 uniprotkb:O95295 intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3 intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56 psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym) psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym) psi-mi:"MI:0096"(pull down) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159987|imex:IM-17362-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1 ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1 - - - comment:All eight subunits of BLOC-1 were coexpressed from a single polycistronic plasmid in E. coli. Coomassie staining showed no Ecoli proteins to co-purify with the 8 proteins.|figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606 rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606 intact-crc:20B59DA120D950DD|rigid:9qvtgS6jBZzKSiDLsBzBq2+3jOQ false sufficient binding region:1-217|glutathione s tranferase tag:c-c - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q96EV8 uniprotkb:Q6QNY0 intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3 intact:EBI-465930|ensembl:ENSP00000393840|ensembl:ENSP00000468281|uniprotkb:B2RXB8 psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym) psi-mi:bl1s3_human(display_long)|uniprotkb:BLOC1S3(gene name)|psi-mi:BLOC1S3(display_short)|uniprotkb:BLOS3(gene name synonym) psi-mi:"MI:0096"(pull down) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159987|imex:IM-17362-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1 ensembl:ENSG00000189114(gene)|ensembl:ENST00000433642(transcript)|ensembl:ENST00000587722(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005829"(cytosol)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0030133"(transport vesicle)|go:"GO:0030168"(platelet activation)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032402"(melanosome transport)|go:"GO:0032438"(melanosome organization)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033299"(secretion of lysosomal enzymes)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042493"|go:"GO:0043473"(pigmentation)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR017245(BLOC-1 complex, subunit 3)|reactome:R-HSA-432722|refseq:NP_997715.1 - - - comment:All eight subunits of BLOC-1 were coexpressed from a single polycistronic plasmid in E. coli. Coomassie staining showed no Ecoli proteins to co-purify with the 8 proteins.|figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606 rogid:OI9LHYYxsDLKtTyzmhndondbJb49606 intact-crc:20B59DA120D950DD|rigid:9qvtgS6jBZzKSiDLsBzBq2+3jOQ false sufficient binding region:1-217|glutathione s tranferase tag:c-c - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q96EV8 uniprotkb:Q6QNY1 intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3 intact:EBI-465872|ensembl:ENSP00000359398|uniprotkb:Q5W040|uniprotkb:Q8WUI8|uniprotkb:B4DQV2 psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym) psi-mi:bl1s2_human(display_long)|uniprotkb:BLOC1S2(gene name)|psi-mi:BLOC1S2(display_short)|uniprotkb:BLOS2(gene name synonym)|uniprotkb:CEAP(gene name synonym)|uniprotkb:Centrosome-associated protein(gene name synonym) psi-mi:"MI:0096"(pull down) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159987|imex:IM-17362-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1 go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016197"(endosomal transport)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|ensembl:ENSG00000196072(gene)|go:"GO:0032418"(lysosome localization)|ensembl:ENST00000370372(transcript)|go:"GO:0032438"(melanosome organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0005634"(nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR019269|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0008022"(protein C-terminus binding)|refseq:NP_776170.2|refseq:NP_001001342.1|refseq:NP_001269366.1|refseq:NP_001269367.1 - - - comment:All eight subunits of BLOC-1 were coexpressed from a single polycistronic plasmid in E. coli. Coomassie staining showed no Ecoli proteins to co-purify with the 8 proteins.|figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606 rogid:UFYvRoJEOtMQZa5OEOCt2gHLOm89606 intact-crc:20B59DA120D950DD|rigid:9qvtgS6jBZzKSiDLsBzBq2+3jOQ false sufficient binding region:1-217|glutathione s tranferase tag:c-c - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q96EV8 uniprotkb:P78537 intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3 intact:EBI-348630|uniprotkb:Q6NZ45|uniprotkb:A1L4Q9|ensembl:ENSP00000447537 psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym) psi-mi:bl1s1_human(display_long)|uniprotkb:BLOC1S1(gene name)|psi-mi:BLOC1S1(display_short)|uniprotkb:BLOS1(gene name synonym)|uniprotkb:RT14(gene name synonym)|uniprotkb:GCN5L1(gene name synonym)|uniprotkb:GCN5-like protein 1(gene name synonym)|uniprotkb:Protein RT14(gene name synonym) psi-mi:"MI:0096"(pull down) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159987|imex:IM-17362-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1 refseq:NP_001478.2|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR009395(GCN5-like 1)|mint:P78537|reactome:R-HSA-432720|reactome:R-HSA-432722|ensembl:ENSG00000135441(gene)|ensembl:ENST00000548925(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016197"(endosomal transport)|go:"GO:0018394"(peptidyl-lysine acetylation) - - - comment:All eight subunits of BLOC-1 were coexpressed from a single polycistronic plasmid in E. coli. Coomassie staining showed no Ecoli proteins to co-purify with the 8 proteins.|figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606 rogid:lntB3izez0HoFLPpiAtPBayt+G49606 intact-crc:20B59DA120D950DD|rigid:9qvtgS6jBZzKSiDLsBzBq2+3jOQ false sufficient binding region:1-217|glutathione s tranferase tag:c-c - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q96EV8 uniprotkb:Q9UL45 intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3 intact:EBI-465781|ensembl:ENSP00000220531 psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym) psi-mi:bl1s6_human(display_long)|uniprotkb:BLOC1S6(gene name)|psi-mi:BLOC1S6(display_short)|uniprotkb:PA(gene name synonym)|uniprotkb:PLDN(gene name synonym)|uniprotkb:Pallid protein homolog(gene name synonym)|uniprotkb:Pallidin(gene name synonym)|uniprotkb:Syntaxin 13-interacting protein(gene name synonym) psi-mi:"MI:0096"(pull down) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6159987|imex:IM-17362-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1 ensembl:ENSG00000104164(gene)|ensembl:ENST00000220531(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032402"(melanosome transport)|go:"GO:0032438"(melanosome organization)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033299"(secretion of lysosomal enzymes)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050942"(positive regulation of pigment cell differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0098793"(presynapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR017242(BLOC-1 complex, pallidin subunit)|go:"GO:0031175"(neuron projection development)|interpro:IPR028119|mint:Q9UL45|reactome:R-HSA-432722|refseq:NP_036520.1 - - - comment:All eight subunits of BLOC-1 were coexpressed from a single polycistronic plasmid in E. coli. Coomassie staining showed no Ecoli proteins to co-purify with the 8 proteins.|figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606 rogid:s5/ikwpqtA8Mm8gMd6ttfmBBKSA9606 intact-crc:20B59DA120D950DD|rigid:9qvtgS6jBZzKSiDLsBzBq2+3jOQ false sufficient binding region:1-217|glutathione s tranferase tag:c-c his tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9UL45 uniprotkb:Q9NUP1 intact:EBI-465781|ensembl:ENSP00000220531 intact:EBI-465852|uniprotkb:Q96G84|ensembl:ENSP00000318128|uniprotkb:Q6NVY6 psi-mi:bl1s6_human(display_long)|uniprotkb:BLOC1S6(gene name)|psi-mi:BLOC1S6(display_short)|uniprotkb:PA(gene name synonym)|uniprotkb:PLDN(gene name synonym)|uniprotkb:Pallid protein homolog(gene name synonym)|uniprotkb:Pallidin(gene name synonym)|uniprotkb:Syntaxin 13-interacting protein(gene name synonym) psi-mi:bl1s4_human(display_long)|uniprotkb:BLOC1S4(gene name)|psi-mi:BLOC1S4(display_short)|uniprotkb:CNO(gene name synonym)|uniprotkb:Protein cappuccino homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160120|imex:IM-17362-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000104164(gene)|ensembl:ENST00000220531(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032402"(melanosome transport)|go:"GO:0032438"(melanosome organization)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033299"(secretion of lysosomal enzymes)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050942"(positive regulation of pigment cell differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0098793"(presynapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR017242(BLOC-1 complex, pallidin subunit)|go:"GO:0031175"(neuron projection development)|interpro:IPR028119|mint:Q9UL45|reactome:R-HSA-432722|refseq:NP_036520.1 go:"GO:0008089"(anterograde axonal transport)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032438"(melanosome organization)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0070527"(platelet aggregation)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR024857|reactome:R-HSA-432722|ensembl:ENSG00000186222(gene)|ensembl:ENST00000320776(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_060836.1 - - - comment:All eight subunits of BLOC-1 were coexpressed from a single polycistronic plasmid in E. coli. Coomassie staining showed no Ecoli proteins to co-purify with the 8 proteins.|figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:s5/ikwpqtA8Mm8gMd6ttfmBBKSA9606 rogid:OGP3Nz9cdPa/BmzSDjUtdbg5XpE9606 intact-crc:7E780E876F3CD4B1|rigid:9qvtgS6jBZzKSiDLsBzBq2+3jOQ false his tag:n-n sufficient binding region:1-177 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9UL45 uniprotkb:Q8TDH9 intact:EBI-465781|ensembl:ENSP00000220531 intact:EBI-465861|ensembl:ENSP00000380598|uniprotkb:Q0VDJ7|uniprotkb:Q5THS1|uniprotkb:Q68D56|uniprotkb:Q8N5F9|uniprotkb:Q9NU16|uniprotkb:B4DVM2|uniprotkb:Q0VDJ6 psi-mi:bl1s6_human(display_long)|uniprotkb:BLOC1S6(gene name)|psi-mi:BLOC1S6(display_short)|uniprotkb:PA(gene name synonym)|uniprotkb:PLDN(gene name synonym)|uniprotkb:Pallid protein homolog(gene name synonym)|uniprotkb:Pallidin(gene name synonym)|uniprotkb:Syntaxin 13-interacting protein(gene name synonym) psi-mi:bl1s5_human(display_long)|uniprotkb:BLOC1S5(gene name)|psi-mi:BLOC1S5(display_short)|uniprotkb:MUTED(gene name synonym)|uniprotkb:Protein Muted homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160120|imex:IM-17362-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000104164(gene)|ensembl:ENST00000220531(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032402"(melanosome transport)|go:"GO:0032438"(melanosome organization)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033299"(secretion of lysosomal enzymes)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050942"(positive regulation of pigment cell differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0098793"(presynapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR017242(BLOC-1 complex, pallidin subunit)|go:"GO:0031175"(neuron projection development)|interpro:IPR028119|mint:Q9UL45|reactome:R-HSA-432722|refseq:NP_036520.1 ensembl:ENSG00000188428(gene)|ensembl:ENST00000397457(transcript)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032402"(melanosome transport)|go:"GO:0032438"(melanosome organization)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050942"(positive regulation of pigment cell differentiation)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR017243(BLOC-1 complex, muted subunit)|refseq:NP_958437.1|refseq:NP_001186251.1 - - - comment:All eight subunits of BLOC-1 were coexpressed from a single polycistronic plasmid in E. coli. Coomassie staining showed no Ecoli proteins to co-purify with the 8 proteins.|figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:s5/ikwpqtA8Mm8gMd6ttfmBBKSA9606 rogid:Bbv2N+NCAJ0baNXhhFYIsIqDwSg9606 intact-crc:7E780E876F3CD4B1|rigid:9qvtgS6jBZzKSiDLsBzBq2+3jOQ false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9UL45 uniprotkb:Q96EV8 intact:EBI-465781|ensembl:ENSP00000220531 intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3 psi-mi:bl1s6_human(display_long)|uniprotkb:BLOC1S6(gene name)|psi-mi:BLOC1S6(display_short)|uniprotkb:PA(gene name synonym)|uniprotkb:PLDN(gene name synonym)|uniprotkb:Pallid protein homolog(gene name synonym)|uniprotkb:Pallidin(gene name synonym)|uniprotkb:Syntaxin 13-interacting protein(gene name synonym) psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym) psi-mi:"MI:0096"(pull down) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160120|imex:IM-17362-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000104164(gene)|ensembl:ENST00000220531(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032402"(melanosome transport)|go:"GO:0032438"(melanosome organization)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033299"(secretion of lysosomal enzymes)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050942"(positive regulation of pigment cell differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0098793"(presynapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR017242(BLOC-1 complex, pallidin subunit)|go:"GO:0031175"(neuron projection development)|interpro:IPR028119|mint:Q9UL45|reactome:R-HSA-432722|refseq:NP_036520.1 ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1 - - - comment:All eight subunits of BLOC-1 were coexpressed from a single polycistronic plasmid in E. coli. Coomassie staining showed no Ecoli proteins to co-purify with the 8 proteins.|figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:s5/ikwpqtA8Mm8gMd6ttfmBBKSA9606 rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606 intact-crc:7E780E876F3CD4B1|rigid:9qvtgS6jBZzKSiDLsBzBq2+3jOQ false his tag:n-n glutathione s tranferase tag:c-c - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9UL45 uniprotkb:Q6QNY0 intact:EBI-465781|ensembl:ENSP00000220531 intact:EBI-465930|ensembl:ENSP00000393840|ensembl:ENSP00000468281|uniprotkb:B2RXB8 psi-mi:bl1s6_human(display_long)|uniprotkb:BLOC1S6(gene name)|psi-mi:BLOC1S6(display_short)|uniprotkb:PA(gene name synonym)|uniprotkb:PLDN(gene name synonym)|uniprotkb:Pallid protein homolog(gene name synonym)|uniprotkb:Pallidin(gene name synonym)|uniprotkb:Syntaxin 13-interacting protein(gene name synonym) psi-mi:bl1s3_human(display_long)|uniprotkb:BLOC1S3(gene name)|psi-mi:BLOC1S3(display_short)|uniprotkb:BLOS3(gene name synonym) psi-mi:"MI:0096"(pull down) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160120|imex:IM-17362-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000104164(gene)|ensembl:ENST00000220531(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032402"(melanosome transport)|go:"GO:0032438"(melanosome organization)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033299"(secretion of lysosomal enzymes)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050942"(positive regulation of pigment cell differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0098793"(presynapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR017242(BLOC-1 complex, pallidin subunit)|go:"GO:0031175"(neuron projection development)|interpro:IPR028119|mint:Q9UL45|reactome:R-HSA-432722|refseq:NP_036520.1 ensembl:ENSG00000189114(gene)|ensembl:ENST00000433642(transcript)|ensembl:ENST00000587722(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005829"(cytosol)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0030133"(transport vesicle)|go:"GO:0030168"(platelet activation)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032402"(melanosome transport)|go:"GO:0032438"(melanosome organization)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033299"(secretion of lysosomal enzymes)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042493"|go:"GO:0043473"(pigmentation)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR017245(BLOC-1 complex, subunit 3)|reactome:R-HSA-432722|refseq:NP_997715.1 - - - comment:All eight subunits of BLOC-1 were coexpressed from a single polycistronic plasmid in E. coli. Coomassie staining showed no Ecoli proteins to co-purify with the 8 proteins.|figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:s5/ikwpqtA8Mm8gMd6ttfmBBKSA9606 rogid:OI9LHYYxsDLKtTyzmhndondbJb49606 intact-crc:7E780E876F3CD4B1|rigid:9qvtgS6jBZzKSiDLsBzBq2+3jOQ false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9UL45 uniprotkb:O95295 intact:EBI-465781|ensembl:ENSP00000220531 intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56 psi-mi:bl1s6_human(display_long)|uniprotkb:BLOC1S6(gene name)|psi-mi:BLOC1S6(display_short)|uniprotkb:PA(gene name synonym)|uniprotkb:PLDN(gene name synonym)|uniprotkb:Pallid protein homolog(gene name synonym)|uniprotkb:Pallidin(gene name synonym)|uniprotkb:Syntaxin 13-interacting protein(gene name synonym) psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym) psi-mi:"MI:0096"(pull down) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160120|imex:IM-17362-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000104164(gene)|ensembl:ENST00000220531(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032402"(melanosome transport)|go:"GO:0032438"(melanosome organization)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033299"(secretion of lysosomal enzymes)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050942"(positive regulation of pigment cell differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0098793"(presynapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR017242(BLOC-1 complex, pallidin subunit)|go:"GO:0031175"(neuron projection development)|interpro:IPR028119|mint:Q9UL45|reactome:R-HSA-432722|refseq:NP_036520.1 ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1 - - - comment:All eight subunits of BLOC-1 were coexpressed from a single polycistronic plasmid in E. coli. Coomassie staining showed no Ecoli proteins to co-purify with the 8 proteins.|figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:s5/ikwpqtA8Mm8gMd6ttfmBBKSA9606 rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606 intact-crc:7E780E876F3CD4B1|rigid:9qvtgS6jBZzKSiDLsBzBq2+3jOQ false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9UL45 uniprotkb:Q6QNY1 intact:EBI-465781|ensembl:ENSP00000220531 intact:EBI-465872|ensembl:ENSP00000359398|uniprotkb:Q5W040|uniprotkb:Q8WUI8|uniprotkb:B4DQV2 psi-mi:bl1s6_human(display_long)|uniprotkb:BLOC1S6(gene name)|psi-mi:BLOC1S6(display_short)|uniprotkb:PA(gene name synonym)|uniprotkb:PLDN(gene name synonym)|uniprotkb:Pallid protein homolog(gene name synonym)|uniprotkb:Pallidin(gene name synonym)|uniprotkb:Syntaxin 13-interacting protein(gene name synonym) psi-mi:bl1s2_human(display_long)|uniprotkb:BLOC1S2(gene name)|psi-mi:BLOC1S2(display_short)|uniprotkb:BLOS2(gene name synonym)|uniprotkb:CEAP(gene name synonym)|uniprotkb:Centrosome-associated protein(gene name synonym) psi-mi:"MI:0096"(pull down) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160120|imex:IM-17362-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000104164(gene)|ensembl:ENST00000220531(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032402"(melanosome transport)|go:"GO:0032438"(melanosome organization)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033299"(secretion of lysosomal enzymes)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050942"(positive regulation of pigment cell differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0098793"(presynapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR017242(BLOC-1 complex, pallidin subunit)|go:"GO:0031175"(neuron projection development)|interpro:IPR028119|mint:Q9UL45|reactome:R-HSA-432722|refseq:NP_036520.1 go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016197"(endosomal transport)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|ensembl:ENSG00000196072(gene)|go:"GO:0032418"(lysosome localization)|ensembl:ENST00000370372(transcript)|go:"GO:0032438"(melanosome organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0005634"(nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR019269|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0008022"(protein C-terminus binding)|refseq:NP_776170.2|refseq:NP_001001342.1|refseq:NP_001269366.1|refseq:NP_001269367.1 - - - comment:All eight subunits of BLOC-1 were coexpressed from a single polycistronic plasmid in E. coli. Coomassie staining showed no Ecoli proteins to co-purify with the 8 proteins.|figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:s5/ikwpqtA8Mm8gMd6ttfmBBKSA9606 rogid:UFYvRoJEOtMQZa5OEOCt2gHLOm89606 intact-crc:7E780E876F3CD4B1|rigid:9qvtgS6jBZzKSiDLsBzBq2+3jOQ false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9UL45 uniprotkb:P78537 intact:EBI-465781|ensembl:ENSP00000220531 intact:EBI-348630|uniprotkb:Q6NZ45|uniprotkb:A1L4Q9|ensembl:ENSP00000447537 psi-mi:bl1s6_human(display_long)|uniprotkb:BLOC1S6(gene name)|psi-mi:BLOC1S6(display_short)|uniprotkb:PA(gene name synonym)|uniprotkb:PLDN(gene name synonym)|uniprotkb:Pallid protein homolog(gene name synonym)|uniprotkb:Pallidin(gene name synonym)|uniprotkb:Syntaxin 13-interacting protein(gene name synonym) psi-mi:bl1s1_human(display_long)|uniprotkb:BLOC1S1(gene name)|psi-mi:BLOC1S1(display_short)|uniprotkb:BLOS1(gene name synonym)|uniprotkb:RT14(gene name synonym)|uniprotkb:GCN5L1(gene name synonym)|uniprotkb:GCN5-like protein 1(gene name synonym)|uniprotkb:Protein RT14(gene name synonym) psi-mi:"MI:0096"(pull down) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160120|imex:IM-17362-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000104164(gene)|ensembl:ENST00000220531(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032402"(melanosome transport)|go:"GO:0032438"(melanosome organization)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033299"(secretion of lysosomal enzymes)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050942"(positive regulation of pigment cell differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0098793"(presynapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR017242(BLOC-1 complex, pallidin subunit)|go:"GO:0031175"(neuron projection development)|interpro:IPR028119|mint:Q9UL45|reactome:R-HSA-432722|refseq:NP_036520.1 refseq:NP_001478.2|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR009395(GCN5-like 1)|mint:P78537|reactome:R-HSA-432720|reactome:R-HSA-432722|ensembl:ENSG00000135441(gene)|ensembl:ENST00000548925(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016197"(endosomal transport)|go:"GO:0018394"(peptidyl-lysine acetylation) - - - comment:All eight subunits of BLOC-1 were coexpressed from a single polycistronic plasmid in E. coli. Coomassie staining showed no Ecoli proteins to co-purify with the 8 proteins.|figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:s5/ikwpqtA8Mm8gMd6ttfmBBKSA9606 rogid:lntB3izez0HoFLPpiAtPBayt+G49606 intact-crc:7E780E876F3CD4B1|rigid:9qvtgS6jBZzKSiDLsBzBq2+3jOQ false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P78537 uniprotkb:Q6QNY1 intact:EBI-348630|uniprotkb:Q6NZ45|uniprotkb:A1L4Q9|ensembl:ENSP00000447537 intact:EBI-465872|ensembl:ENSP00000359398|uniprotkb:Q5W040|uniprotkb:Q8WUI8|uniprotkb:B4DQV2 psi-mi:bl1s1_human(display_long)|uniprotkb:BLOC1S1(gene name)|psi-mi:BLOC1S1(display_short)|uniprotkb:BLOS1(gene name synonym)|uniprotkb:RT14(gene name synonym)|uniprotkb:GCN5L1(gene name synonym)|uniprotkb:GCN5-like protein 1(gene name synonym)|uniprotkb:Protein RT14(gene name synonym) psi-mi:bl1s2_human(display_long)|uniprotkb:BLOC1S2(gene name)|psi-mi:BLOC1S2(display_short)|uniprotkb:BLOS2(gene name synonym)|uniprotkb:CEAP(gene name synonym)|uniprotkb:Centrosome-associated protein(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160105|imex:IM-17362-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001478.2|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR009395(GCN5-like 1)|mint:P78537|reactome:R-HSA-432720|reactome:R-HSA-432722|ensembl:ENSG00000135441(gene)|ensembl:ENST00000548925(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016197"(endosomal transport)|go:"GO:0018394"(peptidyl-lysine acetylation) go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016197"(endosomal transport)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|ensembl:ENSG00000196072(gene)|go:"GO:0032418"(lysosome localization)|ensembl:ENST00000370372(transcript)|go:"GO:0032438"(melanosome organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0005634"(nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR019269|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0008022"(protein C-terminus binding)|refseq:NP_776170.2|refseq:NP_001001342.1|refseq:NP_001269366.1|refseq:NP_001269367.1 - - - comment:"Subsequent analysis suggests BLOC-1 consists of eight globular domains of approximately equal diameter (30 A) connected in a linear chain."|figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:lntB3izez0HoFLPpiAtPBayt+G49606 rogid:UFYvRoJEOtMQZa5OEOCt2gHLOm89606 intact-crc:37EC7075BA59E9C2|rigid:9qvtgS6jBZzKSiDLsBzBq2+3jOQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P78537 uniprotkb:Q6QNY0 intact:EBI-348630|uniprotkb:Q6NZ45|uniprotkb:A1L4Q9|ensembl:ENSP00000447537 intact:EBI-465930|ensembl:ENSP00000393840|ensembl:ENSP00000468281|uniprotkb:B2RXB8 psi-mi:bl1s1_human(display_long)|uniprotkb:BLOC1S1(gene name)|psi-mi:BLOC1S1(display_short)|uniprotkb:BLOS1(gene name synonym)|uniprotkb:RT14(gene name synonym)|uniprotkb:GCN5L1(gene name synonym)|uniprotkb:GCN5-like protein 1(gene name synonym)|uniprotkb:Protein RT14(gene name synonym) psi-mi:bl1s3_human(display_long)|uniprotkb:BLOC1S3(gene name)|psi-mi:BLOC1S3(display_short)|uniprotkb:BLOS3(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160105|imex:IM-17362-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001478.2|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR009395(GCN5-like 1)|mint:P78537|reactome:R-HSA-432720|reactome:R-HSA-432722|ensembl:ENSG00000135441(gene)|ensembl:ENST00000548925(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016197"(endosomal transport)|go:"GO:0018394"(peptidyl-lysine acetylation) ensembl:ENSG00000189114(gene)|ensembl:ENST00000433642(transcript)|ensembl:ENST00000587722(transcript)|go:"GO:0001654"(eye development)|go:"GO:0005829"(cytosol)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0030133"(transport vesicle)|go:"GO:0030168"(platelet activation)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032402"(melanosome transport)|go:"GO:0032438"(melanosome organization)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033299"(secretion of lysosomal enzymes)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042493"|go:"GO:0043473"(pigmentation)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR017245(BLOC-1 complex, subunit 3)|reactome:R-HSA-432722|refseq:NP_997715.1 - - - comment:"Subsequent analysis suggests BLOC-1 consists of eight globular domains of approximately equal diameter (30 A) connected in a linear chain."|figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:lntB3izez0HoFLPpiAtPBayt+G49606 rogid:OI9LHYYxsDLKtTyzmhndondbJb49606 intact-crc:37EC7075BA59E9C2|rigid:9qvtgS6jBZzKSiDLsBzBq2+3jOQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P78537 uniprotkb:Q9NUP1 intact:EBI-348630|uniprotkb:Q6NZ45|uniprotkb:A1L4Q9|ensembl:ENSP00000447537 intact:EBI-465852|uniprotkb:Q96G84|ensembl:ENSP00000318128|uniprotkb:Q6NVY6 psi-mi:bl1s1_human(display_long)|uniprotkb:BLOC1S1(gene name)|psi-mi:BLOC1S1(display_short)|uniprotkb:BLOS1(gene name synonym)|uniprotkb:RT14(gene name synonym)|uniprotkb:GCN5L1(gene name synonym)|uniprotkb:GCN5-like protein 1(gene name synonym)|uniprotkb:Protein RT14(gene name synonym) psi-mi:bl1s4_human(display_long)|uniprotkb:BLOC1S4(gene name)|psi-mi:BLOC1S4(display_short)|uniprotkb:CNO(gene name synonym)|uniprotkb:Protein cappuccino homolog(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160105|imex:IM-17362-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001478.2|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR009395(GCN5-like 1)|mint:P78537|reactome:R-HSA-432720|reactome:R-HSA-432722|ensembl:ENSG00000135441(gene)|ensembl:ENST00000548925(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016197"(endosomal transport)|go:"GO:0018394"(peptidyl-lysine acetylation) go:"GO:0008089"(anterograde axonal transport)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032438"(melanosome organization)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0070527"(platelet aggregation)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR024857|reactome:R-HSA-432722|ensembl:ENSG00000186222(gene)|ensembl:ENST00000320776(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_060836.1 - - - comment:"Subsequent analysis suggests BLOC-1 consists of eight globular domains of approximately equal diameter (30 A) connected in a linear chain."|figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:lntB3izez0HoFLPpiAtPBayt+G49606 rogid:OGP3Nz9cdPa/BmzSDjUtdbg5XpE9606 intact-crc:37EC7075BA59E9C2|rigid:9qvtgS6jBZzKSiDLsBzBq2+3jOQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P78537 uniprotkb:Q8TDH9 intact:EBI-348630|uniprotkb:Q6NZ45|uniprotkb:A1L4Q9|ensembl:ENSP00000447537 intact:EBI-465861|ensembl:ENSP00000380598|uniprotkb:Q0VDJ7|uniprotkb:Q5THS1|uniprotkb:Q68D56|uniprotkb:Q8N5F9|uniprotkb:Q9NU16|uniprotkb:B4DVM2|uniprotkb:Q0VDJ6 psi-mi:bl1s1_human(display_long)|uniprotkb:BLOC1S1(gene name)|psi-mi:BLOC1S1(display_short)|uniprotkb:BLOS1(gene name synonym)|uniprotkb:RT14(gene name synonym)|uniprotkb:GCN5L1(gene name synonym)|uniprotkb:GCN5-like protein 1(gene name synonym)|uniprotkb:Protein RT14(gene name synonym) psi-mi:bl1s5_human(display_long)|uniprotkb:BLOC1S5(gene name)|psi-mi:BLOC1S5(display_short)|uniprotkb:MUTED(gene name synonym)|uniprotkb:Protein Muted homolog(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160105|imex:IM-17362-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001478.2|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR009395(GCN5-like 1)|mint:P78537|reactome:R-HSA-432720|reactome:R-HSA-432722|ensembl:ENSG00000135441(gene)|ensembl:ENST00000548925(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016197"(endosomal transport)|go:"GO:0018394"(peptidyl-lysine acetylation) ensembl:ENSG00000188428(gene)|ensembl:ENST00000397457(transcript)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032402"(melanosome transport)|go:"GO:0032438"(melanosome organization)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050942"(positive regulation of pigment cell differentiation)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR017243(BLOC-1 complex, muted subunit)|refseq:NP_958437.1|refseq:NP_001186251.1 - - - comment:"Subsequent analysis suggests BLOC-1 consists of eight globular domains of approximately equal diameter (30 A) connected in a linear chain."|figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:lntB3izez0HoFLPpiAtPBayt+G49606 rogid:Bbv2N+NCAJ0baNXhhFYIsIqDwSg9606 intact-crc:37EC7075BA59E9C2|rigid:9qvtgS6jBZzKSiDLsBzBq2+3jOQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P78537 uniprotkb:Q9UL45 intact:EBI-348630|uniprotkb:Q6NZ45|uniprotkb:A1L4Q9|ensembl:ENSP00000447537 intact:EBI-465781|ensembl:ENSP00000220531 psi-mi:bl1s1_human(display_long)|uniprotkb:BLOC1S1(gene name)|psi-mi:BLOC1S1(display_short)|uniprotkb:BLOS1(gene name synonym)|uniprotkb:RT14(gene name synonym)|uniprotkb:GCN5L1(gene name synonym)|uniprotkb:GCN5-like protein 1(gene name synonym)|uniprotkb:Protein RT14(gene name synonym) psi-mi:bl1s6_human(display_long)|uniprotkb:BLOC1S6(gene name)|psi-mi:BLOC1S6(display_short)|uniprotkb:PA(gene name synonym)|uniprotkb:PLDN(gene name synonym)|uniprotkb:Pallid protein homolog(gene name synonym)|uniprotkb:Pallidin(gene name synonym)|uniprotkb:Syntaxin 13-interacting protein(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160105|imex:IM-17362-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001478.2|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR009395(GCN5-like 1)|mint:P78537|reactome:R-HSA-432720|reactome:R-HSA-432722|ensembl:ENSG00000135441(gene)|ensembl:ENST00000548925(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016197"(endosomal transport)|go:"GO:0018394"(peptidyl-lysine acetylation) ensembl:ENSG00000104164(gene)|ensembl:ENST00000220531(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032402"(melanosome transport)|go:"GO:0032438"(melanosome organization)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033299"(secretion of lysosomal enzymes)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050942"(positive regulation of pigment cell differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0098793"(presynapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR017242(BLOC-1 complex, pallidin subunit)|go:"GO:0031175"(neuron projection development)|interpro:IPR028119|mint:Q9UL45|reactome:R-HSA-432722|refseq:NP_036520.1 - - - comment:"Subsequent analysis suggests BLOC-1 consists of eight globular domains of approximately equal diameter (30 A) connected in a linear chain."|figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:lntB3izez0HoFLPpiAtPBayt+G49606 rogid:s5/ikwpqtA8Mm8gMd6ttfmBBKSA9606 intact-crc:37EC7075BA59E9C2|rigid:9qvtgS6jBZzKSiDLsBzBq2+3jOQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P78537 uniprotkb:Q96EV8 intact:EBI-348630|uniprotkb:Q6NZ45|uniprotkb:A1L4Q9|ensembl:ENSP00000447537 intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3 psi-mi:bl1s1_human(display_long)|uniprotkb:BLOC1S1(gene name)|psi-mi:BLOC1S1(display_short)|uniprotkb:BLOS1(gene name synonym)|uniprotkb:RT14(gene name synonym)|uniprotkb:GCN5L1(gene name synonym)|uniprotkb:GCN5-like protein 1(gene name synonym)|uniprotkb:Protein RT14(gene name synonym) psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160105|imex:IM-17362-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001478.2|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR009395(GCN5-like 1)|mint:P78537|reactome:R-HSA-432720|reactome:R-HSA-432722|ensembl:ENSG00000135441(gene)|ensembl:ENST00000548925(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016197"(endosomal transport)|go:"GO:0018394"(peptidyl-lysine acetylation) ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1 - - - comment:"Subsequent analysis suggests BLOC-1 consists of eight globular domains of approximately equal diameter (30 A) connected in a linear chain."|figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:lntB3izez0HoFLPpiAtPBayt+G49606 rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606 intact-crc:37EC7075BA59E9C2|rigid:9qvtgS6jBZzKSiDLsBzBq2+3jOQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P78537 uniprotkb:O95295 intact:EBI-348630|uniprotkb:Q6NZ45|uniprotkb:A1L4Q9|ensembl:ENSP00000447537 intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56 psi-mi:bl1s1_human(display_long)|uniprotkb:BLOC1S1(gene name)|psi-mi:BLOC1S1(display_short)|uniprotkb:BLOS1(gene name synonym)|uniprotkb:RT14(gene name synonym)|uniprotkb:GCN5L1(gene name synonym)|uniprotkb:GCN5-like protein 1(gene name synonym)|uniprotkb:Protein RT14(gene name synonym) psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160105|imex:IM-17362-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001478.2|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR009395(GCN5-like 1)|mint:P78537|reactome:R-HSA-432720|reactome:R-HSA-432722|ensembl:ENSG00000135441(gene)|ensembl:ENST00000548925(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016197"(endosomal transport)|go:"GO:0018394"(peptidyl-lysine acetylation) ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1 - - - comment:"Subsequent analysis suggests BLOC-1 consists of eight globular domains of approximately equal diameter (30 A) connected in a linear chain."|figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:lntB3izez0HoFLPpiAtPBayt+G49606 rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606 intact-crc:37EC7075BA59E9C2|rigid:9qvtgS6jBZzKSiDLsBzBq2+3jOQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UL45 uniprotkb:Q9NUP1 intact:EBI-465781|ensembl:ENSP00000220531 intact:EBI-465852|uniprotkb:Q96G84|ensembl:ENSP00000318128|uniprotkb:Q6NVY6 psi-mi:bl1s6_human(display_long)|uniprotkb:BLOC1S6(gene name)|psi-mi:BLOC1S6(display_short)|uniprotkb:PA(gene name synonym)|uniprotkb:PLDN(gene name synonym)|uniprotkb:Pallid protein homolog(gene name synonym)|uniprotkb:Pallidin(gene name synonym)|uniprotkb:Syntaxin 13-interacting protein(gene name synonym) psi-mi:bl1s4_human(display_long)|uniprotkb:BLOC1S4(gene name)|psi-mi:BLOC1S4(display_short)|uniprotkb:CNO(gene name synonym)|uniprotkb:Protein cappuccino homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160156|imex:IM-17362-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000104164(gene)|ensembl:ENST00000220531(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032402"(melanosome transport)|go:"GO:0032438"(melanosome organization)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033299"(secretion of lysosomal enzymes)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050942"(positive regulation of pigment cell differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0098793"(presynapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR017242(BLOC-1 complex, pallidin subunit)|go:"GO:0031175"(neuron projection development)|interpro:IPR028119|mint:Q9UL45|reactome:R-HSA-432722|refseq:NP_036520.1 go:"GO:0008089"(anterograde axonal transport)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032438"(melanosome organization)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0070527"(platelet aggregation)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR024857|reactome:R-HSA-432722|ensembl:ENSG00000186222(gene)|ensembl:ENST00000320776(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_060836.1 - - - comment:All eight subunits of BLOC-1 were coexpressed from a single polycistronic plasmid in E. coli. Coomassie staining showed no Ecoli proteins to co-purify with the 8 proteins.|figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:s5/ikwpqtA8Mm8gMd6ttfmBBKSA9606 rogid:OGP3Nz9cdPa/BmzSDjUtdbg5XpE9606 intact-crc:1EA0AA14E338725D|rigid:eeKxmJ/jvTifnIkWg13ybEPnSZA false his tag:c-c sufficient binding region:1-177 - - psi-mi:"MI:0039"(edman degradation) psi-mi:"MI:0039"(edman degradation) uniprotkb:Q9UL45 uniprotkb:P78537 intact:EBI-465781|ensembl:ENSP00000220531 intact:EBI-348630|uniprotkb:Q6NZ45|uniprotkb:A1L4Q9|ensembl:ENSP00000447537 psi-mi:bl1s6_human(display_long)|uniprotkb:BLOC1S6(gene name)|psi-mi:BLOC1S6(display_short)|uniprotkb:PA(gene name synonym)|uniprotkb:PLDN(gene name synonym)|uniprotkb:Pallid protein homolog(gene name synonym)|uniprotkb:Pallidin(gene name synonym)|uniprotkb:Syntaxin 13-interacting protein(gene name synonym) psi-mi:bl1s1_human(display_long)|uniprotkb:BLOC1S1(gene name)|psi-mi:BLOC1S1(display_short)|uniprotkb:BLOS1(gene name synonym)|uniprotkb:RT14(gene name synonym)|uniprotkb:GCN5L1(gene name synonym)|uniprotkb:GCN5-like protein 1(gene name synonym)|uniprotkb:Protein RT14(gene name synonym) psi-mi:"MI:0096"(pull down) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160156|imex:IM-17362-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000104164(gene)|ensembl:ENST00000220531(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032402"(melanosome transport)|go:"GO:0032438"(melanosome organization)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033299"(secretion of lysosomal enzymes)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050942"(positive regulation of pigment cell differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0098793"(presynapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR017242(BLOC-1 complex, pallidin subunit)|go:"GO:0031175"(neuron projection development)|interpro:IPR028119|mint:Q9UL45|reactome:R-HSA-432722|refseq:NP_036520.1 refseq:NP_001478.2|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR009395(GCN5-like 1)|mint:P78537|reactome:R-HSA-432720|reactome:R-HSA-432722|ensembl:ENSG00000135441(gene)|ensembl:ENST00000548925(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016197"(endosomal transport)|go:"GO:0018394"(peptidyl-lysine acetylation) - - - comment:All eight subunits of BLOC-1 were coexpressed from a single polycistronic plasmid in E. coli. Coomassie staining showed no Ecoli proteins to co-purify with the 8 proteins.|figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:s5/ikwpqtA8Mm8gMd6ttfmBBKSA9606 rogid:lntB3izez0HoFLPpiAtPBayt+G49606 intact-crc:1EA0AA14E338725D|rigid:eeKxmJ/jvTifnIkWg13ybEPnSZA false his tag:c-c - - - psi-mi:"MI:0039"(edman degradation) psi-mi:"MI:0039"(edman degradation) uniprotkb:Q6QNY1 uniprotkb:Q96EV8 intact:EBI-465872|ensembl:ENSP00000359398|uniprotkb:Q5W040|uniprotkb:Q8WUI8|uniprotkb:B4DQV2 intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3 psi-mi:bl1s2_human(display_long)|uniprotkb:BLOC1S2(gene name)|psi-mi:BLOC1S2(display_short)|uniprotkb:BLOS2(gene name synonym)|uniprotkb:CEAP(gene name synonym)|uniprotkb:Centrosome-associated protein(gene name synonym) psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160185|imex:IM-17362-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016197"(endosomal transport)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|ensembl:ENSG00000196072(gene)|go:"GO:0032418"(lysosome localization)|ensembl:ENST00000370372(transcript)|go:"GO:0032438"(melanosome organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0005634"(nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR019269|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0008022"(protein C-terminus binding)|refseq:NP_776170.2|refseq:NP_001001342.1|refseq:NP_001269366.1|refseq:NP_001269367.1 ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1 - - - figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:UFYvRoJEOtMQZa5OEOCt2gHLOm89606 rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606 intact-crc:ADC608E28D1269E6|rigid:psr7a21yxKQJlqRl+AoyXW8Z/K8 false - glutathione s tranferase tag:c-c|sufficient binding region:47-140 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q6QNY1 uniprotkb:O95295 intact:EBI-465872|ensembl:ENSP00000359398|uniprotkb:Q5W040|uniprotkb:Q8WUI8|uniprotkb:B4DQV2 intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56 psi-mi:bl1s2_human(display_long)|uniprotkb:BLOC1S2(gene name)|psi-mi:BLOC1S2(display_short)|uniprotkb:BLOS2(gene name synonym)|uniprotkb:CEAP(gene name synonym)|uniprotkb:Centrosome-associated protein(gene name synonym) psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160185|imex:IM-17362-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016197"(endosomal transport)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|ensembl:ENSG00000196072(gene)|go:"GO:0032418"(lysosome localization)|ensembl:ENST00000370372(transcript)|go:"GO:0032438"(melanosome organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0005634"(nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR019269|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0008022"(protein C-terminus binding)|refseq:NP_776170.2|refseq:NP_001001342.1|refseq:NP_001269366.1|refseq:NP_001269367.1 ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1 - - - figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:UFYvRoJEOtMQZa5OEOCt2gHLOm89606 rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606 intact-crc:ADC608E28D1269E6|rigid:psr7a21yxKQJlqRl+AoyXW8Z/K8 false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q6QNY1 uniprotkb:Q96EV8 intact:EBI-465872|ensembl:ENSP00000359398|uniprotkb:Q5W040|uniprotkb:Q8WUI8|uniprotkb:B4DQV2 intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3 psi-mi:bl1s2_human(display_long)|uniprotkb:BLOC1S2(gene name)|psi-mi:BLOC1S2(display_short)|uniprotkb:BLOS2(gene name synonym)|uniprotkb:CEAP(gene name synonym)|uniprotkb:Centrosome-associated protein(gene name synonym) psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160195|imex:IM-17362-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016197"(endosomal transport)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|ensembl:ENSG00000196072(gene)|go:"GO:0032418"(lysosome localization)|ensembl:ENST00000370372(transcript)|go:"GO:0032438"(melanosome organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0005634"(nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR019269|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0008022"(protein C-terminus binding)|refseq:NP_776170.2|refseq:NP_001001342.1|refseq:NP_001269366.1|refseq:NP_001269367.1 ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1 - - - comment:The dysbindin-Snapin-BLOS2 subcomplex eluted at a volume corresponding to a Stokes radius of 5.3 nm. Given the calculated molecular mass of 41.8 kDa for this construct, a Stokes radius of approx. 2.6 nm would have been expected for a hydrated globular protein of the same molecular mass. The actual value of 5.3 nm indicates that the complex is highly elongated.|figure legend:Fig. 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:UFYvRoJEOtMQZa5OEOCt2gHLOm89606 rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606 intact-crc:5F55C22315524C9B|rigid:psr7a21yxKQJlqRl+AoyXW8Z/K8 false - sufficient binding region:47-140 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q6QNY1 uniprotkb:O95295 intact:EBI-465872|ensembl:ENSP00000359398|uniprotkb:Q5W040|uniprotkb:Q8WUI8|uniprotkb:B4DQV2 intact:EBI-296723|ensembl:ENSP00000357674|uniprotkb:Q5SXU8|uniprotkb:D3DV56 psi-mi:bl1s2_human(display_long)|uniprotkb:BLOC1S2(gene name)|psi-mi:BLOC1S2(display_short)|uniprotkb:BLOS2(gene name synonym)|uniprotkb:CEAP(gene name synonym)|uniprotkb:Centrosome-associated protein(gene name synonym) psi-mi:snapn_human(display_long)|uniprotkb:SNAPIN(gene name)|psi-mi:SNAPIN(display_short)|uniprotkb:SNAP25BP(gene name synonym)|uniprotkb:SNAPAP(gene name synonym)|uniprotkb:Synaptosomal-associated protein 25-binding protein(gene name synonym)|uniprotkb:BLOC1S7(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 7(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160195|imex:IM-17362-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016197"(endosomal transport)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|ensembl:ENSG00000196072(gene)|go:"GO:0032418"(lysosome localization)|ensembl:ENST00000370372(transcript)|go:"GO:0032438"(melanosome organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0005634"(nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR019269|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0008022"(protein C-terminus binding)|refseq:NP_776170.2|refseq:NP_001001342.1|refseq:NP_001269366.1|refseq:NP_001269367.1 ensembl:ENSG00000143553(gene)|ensembl:ENST00000368685(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002177"(manchette)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0034629"|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0051604"(protein maturation)|go:"GO:0072553"(terminal button organization)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0099078"(BORC complex)|go:"GO:1902774"(late endosome to lysosome transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR017246(Snapin)|interpro:IPR028119|reactome:R-HSA-432722|refseq:NP_036569.1 - - - comment:The dysbindin-Snapin-BLOS2 subcomplex eluted at a volume corresponding to a Stokes radius of 5.3 nm. Given the calculated molecular mass of 41.8 kDa for this construct, a Stokes radius of approx. 2.6 nm would have been expected for a hydrated globular protein of the same molecular mass. The actual value of 5.3 nm indicates that the complex is highly elongated.|figure legend:Fig. 4C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:UFYvRoJEOtMQZa5OEOCt2gHLOm89606 rogid:V43p5MNgzla9VrcFKxPEIGWxYCM9606 intact-crc:5F55C22315524C9B|rigid:psr7a21yxKQJlqRl+AoyXW8Z/K8 false - - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P78537 uniprotkb:Q9NUP1 intact:EBI-348630|uniprotkb:Q6NZ45|uniprotkb:A1L4Q9|ensembl:ENSP00000447537 intact:EBI-465852|uniprotkb:Q96G84|ensembl:ENSP00000318128|uniprotkb:Q6NVY6 psi-mi:bl1s1_human(display_long)|uniprotkb:BLOC1S1(gene name)|psi-mi:BLOC1S1(display_short)|uniprotkb:BLOS1(gene name synonym)|uniprotkb:RT14(gene name synonym)|uniprotkb:GCN5L1(gene name synonym)|uniprotkb:GCN5-like protein 1(gene name synonym)|uniprotkb:Protein RT14(gene name synonym) psi-mi:bl1s4_human(display_long)|uniprotkb:BLOC1S4(gene name)|psi-mi:BLOC1S4(display_short)|uniprotkb:CNO(gene name synonym)|uniprotkb:Protein cappuccino homolog(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6162280|imex:IM-17362-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001478.2|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR009395(GCN5-like 1)|mint:P78537|reactome:R-HSA-432720|reactome:R-HSA-432722|ensembl:ENSG00000135441(gene)|ensembl:ENST00000548925(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016197"(endosomal transport)|go:"GO:0018394"(peptidyl-lysine acetylation) go:"GO:0008089"(anterograde axonal transport)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032438"(melanosome organization)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0070527"(platelet aggregation)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR024857|reactome:R-HSA-432722|ensembl:ENSG00000186222(gene)|ensembl:ENST00000320776(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_060836.1 - - - figure legend:Fig. 6A, 6B|comment:"The pallidin(33–160)-Cappuccino(1–177)-BLOS1(51–125) subcomplex was found to have a mass of 43.2 kDa and a Stokes radius of 4.6 nm"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:lntB3izez0HoFLPpiAtPBayt+G49606 rogid:OGP3Nz9cdPa/BmzSDjUtdbg5XpE9606 intact-crc:57306A00E0A7E7B6|rigid:eeKxmJ/jvTifnIkWg13ybEPnSZA false sufficient binding region:51-125 sufficient binding region:1-177 1 1 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P78537 uniprotkb:Q9UL45 intact:EBI-348630|uniprotkb:Q6NZ45|uniprotkb:A1L4Q9|ensembl:ENSP00000447537 intact:EBI-465781|ensembl:ENSP00000220531 psi-mi:bl1s1_human(display_long)|uniprotkb:BLOC1S1(gene name)|psi-mi:BLOC1S1(display_short)|uniprotkb:BLOS1(gene name synonym)|uniprotkb:RT14(gene name synonym)|uniprotkb:GCN5L1(gene name synonym)|uniprotkb:GCN5-like protein 1(gene name synonym)|uniprotkb:Protein RT14(gene name synonym) psi-mi:bl1s6_human(display_long)|uniprotkb:BLOC1S6(gene name)|psi-mi:BLOC1S6(display_short)|uniprotkb:PA(gene name synonym)|uniprotkb:PLDN(gene name synonym)|uniprotkb:Pallid protein homolog(gene name synonym)|uniprotkb:Pallidin(gene name synonym)|uniprotkb:Syntaxin 13-interacting protein(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-6162280|imex:IM-17362-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001478.2|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR009395(GCN5-like 1)|mint:P78537|reactome:R-HSA-432720|reactome:R-HSA-432722|ensembl:ENSG00000135441(gene)|ensembl:ENST00000548925(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016197"(endosomal transport)|go:"GO:0018394"(peptidyl-lysine acetylation) ensembl:ENSG00000104164(gene)|ensembl:ENST00000220531(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032402"(melanosome transport)|go:"GO:0032438"(melanosome organization)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033299"(secretion of lysosomal enzymes)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050942"(positive regulation of pigment cell differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0098793"(presynapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR017242(BLOC-1 complex, pallidin subunit)|go:"GO:0031175"(neuron projection development)|interpro:IPR028119|mint:Q9UL45|reactome:R-HSA-432722|refseq:NP_036520.1 - - - figure legend:Fig. 6A, 6B|comment:"The pallidin(33–160)-Cappuccino(1–177)-BLOS1(51–125) subcomplex was found to have a mass of 43.2 kDa and a Stokes radius of 4.6 nm"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:lntB3izez0HoFLPpiAtPBayt+G49606 rogid:s5/ikwpqtA8Mm8gMd6ttfmBBKSA9606 intact-crc:57306A00E0A7E7B6|rigid:eeKxmJ/jvTifnIkWg13ybEPnSZA false sufficient binding region:51-125 sufficient binding region:33-160 1 1 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P78537 uniprotkb:Q9NUP1 intact:EBI-348630|uniprotkb:Q6NZ45|uniprotkb:A1L4Q9|ensembl:ENSP00000447537 intact:EBI-465852|uniprotkb:Q96G84|ensembl:ENSP00000318128|uniprotkb:Q6NVY6 psi-mi:bl1s1_human(display_long)|uniprotkb:BLOC1S1(gene name)|psi-mi:BLOC1S1(display_short)|uniprotkb:BLOS1(gene name synonym)|uniprotkb:RT14(gene name synonym)|uniprotkb:GCN5L1(gene name synonym)|uniprotkb:GCN5-like protein 1(gene name synonym)|uniprotkb:Protein RT14(gene name synonym) psi-mi:bl1s4_human(display_long)|uniprotkb:BLOC1S4(gene name)|psi-mi:BLOC1S4(display_short)|uniprotkb:CNO(gene name synonym)|uniprotkb:Protein cappuccino homolog(gene name synonym) psi-mi:"MI:0605"(enzymatic footprinting) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160223|imex:IM-17362-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001478.2|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR009395(GCN5-like 1)|mint:P78537|reactome:R-HSA-432720|reactome:R-HSA-432722|ensembl:ENSG00000135441(gene)|ensembl:ENST00000548925(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016197"(endosomal transport)|go:"GO:0018394"(peptidyl-lysine acetylation) go:"GO:0008089"(anterograde axonal transport)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032438"(melanosome organization)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0070527"(platelet aggregation)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR024857|reactome:R-HSA-432722|ensembl:ENSG00000186222(gene)|ensembl:ENST00000320776(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_060836.1 - - - figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:lntB3izez0HoFLPpiAtPBayt+G49606 rogid:OGP3Nz9cdPa/BmzSDjUtdbg5XpE9606 intact-crc:98BF2CD734742520|rigid:eeKxmJ/jvTifnIkWg13ybEPnSZA false - sufficient binding region:1-177 - - psi-mi:"MI:0093"(protein sequence identification) psi-mi:"MI:0093"(protein sequence identification) uniprotkb:P78537 uniprotkb:Q9UL45 intact:EBI-348630|uniprotkb:Q6NZ45|uniprotkb:A1L4Q9|ensembl:ENSP00000447537 intact:EBI-465781|ensembl:ENSP00000220531 psi-mi:bl1s1_human(display_long)|uniprotkb:BLOC1S1(gene name)|psi-mi:BLOC1S1(display_short)|uniprotkb:BLOS1(gene name synonym)|uniprotkb:RT14(gene name synonym)|uniprotkb:GCN5L1(gene name synonym)|uniprotkb:GCN5-like protein 1(gene name synonym)|uniprotkb:Protein RT14(gene name synonym) psi-mi:bl1s6_human(display_long)|uniprotkb:BLOC1S6(gene name)|psi-mi:BLOC1S6(display_short)|uniprotkb:PA(gene name synonym)|uniprotkb:PLDN(gene name synonym)|uniprotkb:Pallid protein homolog(gene name synonym)|uniprotkb:Pallidin(gene name synonym)|uniprotkb:Syntaxin 13-interacting protein(gene name synonym) psi-mi:"MI:0605"(enzymatic footprinting) Lee et al. (2012) pubmed:22203680|imex:IM-17362 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-6160223|imex:IM-17362-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001478.2|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032418"(lysosome localization)|go:"GO:0032438"(melanosome organization)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0099078"(BORC complex)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR009395(GCN5-like 1)|mint:P78537|reactome:R-HSA-432720|reactome:R-HSA-432722|ensembl:ENSG00000135441(gene)|ensembl:ENST00000548925(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016197"(endosomal transport)|go:"GO:0018394"(peptidyl-lysine acetylation) ensembl:ENSG00000104164(gene)|ensembl:ENST00000220531(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0032402"(melanosome transport)|go:"GO:0032438"(melanosome organization)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033299"(secretion of lysosomal enzymes)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046907"(intracellular transport)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0050942"(positive regulation of pigment cell differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0098793"(presynapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR017242(BLOC-1 complex, pallidin subunit)|go:"GO:0031175"(neuron projection development)|interpro:IPR028119|mint:Q9UL45|reactome:R-HSA-432722|refseq:NP_036520.1 - - - figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2012/06/15 2014/10/16 rogid:lntB3izez0HoFLPpiAtPBayt+G49606 rogid:s5/ikwpqtA8Mm8gMd6ttfmBBKSA9606 intact-crc:98BF2CD734742520|rigid:eeKxmJ/jvTifnIkWg13ybEPnSZA false - his tag:n-n - - psi-mi:"MI:0093"(protein sequence identification) psi-mi:"MI:0093"(protein sequence identification)