#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:A0R5S2 uniprotkb:A0QS66 intact:EBI-6417840|ensemblbacteria:ABK71925 intact:EBI-2408406|uniprotkb:I7FY06|ensemblbacteria:ABK71951|ensemblbacteria:AFP37802 psi-mi:a0r5s2_mycs2(display_long)|uniprotkb:MSMEG_6292(locus name) psi-mi:rpoc_mycs2(display_long)|uniprotkb:Transcriptase subunit beta'(gene name synonym)|uniprotkb:MSMEG_1368(locus name)|uniprotkb:rpoC(gene name)|psi-mi:rpoC(display_short)|uniprotkb:RNA polymerase subunit beta'(gene name synonym)|uniprotkb:MSMEI_1329(locus name) psi-mi:"MI:0096"(pull down) China et al. (2012) pubmed:22194445|imex:IM-18438 taxid:246196(mycs2)|taxid:246196("Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)") taxid:246196(mycs2)|taxid:246196("Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)") psi-mi:"MI:0914"(association) psi-mi:"MI:0903"(mpidb) intact:EBI-6417836|mpidb:MPIDB-INT-1778|imex:IM-18438-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:ABK71925(transcript)|ensemblbacteria:MSMEG_6292(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR001437(Transcription elongation factor, GreA/GreB region, prokaryotic)|interpro:IPR018151|interpro:IPR023459|refseq:YP_890510.1|refseq:WP_003897712.1|interpro:IPR036953 rcsb pdb:6EYD|rcsb pdb:6F6W|rcsb pdb:6DCF|interpro:IPR038120|refseq:YP_885754.1|interpro:IPR012754(DNA-directed RNA polymerase, subunit beta-prime)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|rcsb pdb:5TW1|refseq:WP_003892756.1|rcsb pdb:5VI8|rcsb pdb:5VI5|rcsb pdb:6CCE|rcsb pdb:6CCV|interpro:IPR042102|rcsb pdb:6VVS|rcsb pdb:6VVT|rcsb pdb:6VVV|rcsb pdb:6YXU|rcsb pdb:6YYS|rcsb pdb:6Z11|ensemblbacteria:ABK71951(transcript)|ensemblbacteria:AFP37802(transcript)|ensemblbacteria:MSMEG_1368(gene)|ensemblbacteria:MSMEI_1329(gene)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding) - - - figure legend:figure 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2012/11/30 2014/10/16 rogid:Pkutghv69DKlB576wJaRXQa3OJI246196 rogid:MTHmATLAdT1hRH9bLpUh70jBSRc246196 intact-crc:E0800E00E070CFB0|rigid:sb+D0/zM7OWCbgxNZhwIobflNa4 false his tag:?-? - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:A0R5S2 uniprotkb:A0QSL8 intact:EBI-6417840|ensemblbacteria:ABK71925 intact:EBI-2408389|uniprotkb:I7G472|ensemblbacteria:ABK71739|ensemblbacteria:AFP37961 psi-mi:a0r5s2_mycs2(display_long)|uniprotkb:MSMEG_6292(locus name) psi-mi:rpoa_mycs2(display_long)|uniprotkb:rpoA(gene name)|psi-mi:rpoA(display_short)|uniprotkb:Transcriptase subunit alpha(gene name synonym)|uniprotkb:RNA polymerase subunit alpha(gene name synonym)|uniprotkb:MSMEG_1524(locus name)|uniprotkb:MSMEI_1488(locus name) psi-mi:"MI:0096"(pull down) China et al. (2012) pubmed:22194445|imex:IM-18438 taxid:246196(mycs2)|taxid:246196("Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)") taxid:246196(mycs2)|taxid:246196("Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)") psi-mi:"MI:0914"(association) psi-mi:"MI:0903"(mpidb) intact:EBI-6417836|mpidb:MPIDB-INT-1778|imex:IM-18438-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:ABK71925(transcript)|ensemblbacteria:MSMEG_6292(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR001437(Transcription elongation factor, GreA/GreB region, prokaryotic)|interpro:IPR018151|interpro:IPR023459|refseq:YP_890510.1|refseq:WP_003897712.1|interpro:IPR036953 rcsb pdb:6EYD|rcsb pdb:6F6W|rcsb pdb:6DCF|refseq:YP_885906.1|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR011773(DNA-directed RNA polymerase, alpha subunit)|interpro:IPR011260(RNA polymerase, alpha subunit, C-terminal)|rcsb pdb:5TW1|refseq:WP_003892912.1|rcsb pdb:5VI8|interpro:IPR036603|interpro:IPR036643|rcsb pdb:5VI5|rcsb pdb:6CCE|rcsb pdb:6CCV|rcsb pdb:6VVS|rcsb pdb:6VVT|rcsb pdb:6VVV|rcsb pdb:6YXU|rcsb pdb:6YYS|rcsb pdb:6Z11|ensemblbacteria:ABK71739(transcript)|ensemblbacteria:AFP37961(transcript)|ensemblbacteria:MSMEG_1524(gene)|ensemblbacteria:MSMEI_1488(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity) - - - figure legend:figure 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2012/11/30 2014/10/16 rogid:Pkutghv69DKlB576wJaRXQa3OJI246196 rogid:BtHqzT1yhyMOwlBRQvbjjc4pn94246196 intact-crc:E0800E00E070CFB0|rigid:sb+D0/zM7OWCbgxNZhwIobflNa4 false his tag:?-? - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:A0R5S2 uniprotkb:A0QWT1 intact:EBI-6417840|ensemblbacteria:ABK71925 intact:EBI-6429600|ensemblbacteria:ABK69545|ensemblbacteria:AFP39441|uniprotkb:I7G8B1 psi-mi:a0r5s2_mycs2(display_long)|uniprotkb:MSMEG_6292(locus name) psi-mi:rpoz_mycs2(display_long)|uniprotkb:MSMEI_2977(locus name)|uniprotkb:rpoZ(gene name)|psi-mi:rpoZ(display_short)|uniprotkb:RNA polymerase omega subunit(gene name synonym)|uniprotkb:Transcriptase subunit omega(gene name synonym)|uniprotkb:MSMEG_3053(locus name) psi-mi:"MI:0096"(pull down) China et al. (2012) pubmed:22194445|imex:IM-18438 taxid:246196(mycs2)|taxid:246196("Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)") taxid:246196(mycs2)|taxid:246196("Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)") psi-mi:"MI:0914"(association) psi-mi:"MI:0903"(mpidb) intact:EBI-6417836|mpidb:MPIDB-INT-1778|imex:IM-18438-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:ABK71925(transcript)|ensemblbacteria:MSMEG_6292(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR001437(Transcription elongation factor, GreA/GreB region, prokaryotic)|interpro:IPR018151|interpro:IPR023459|refseq:YP_890510.1|refseq:WP_003897712.1|interpro:IPR036953 rcsb pdb:6DCF|ensemblbacteria:ABK69545(transcript)|ensemblbacteria:AFP39441(transcript)|ensemblbacteria:MSMEG_3053(gene)|ensemblbacteria:MSMEI_2977(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|rcsb pdb:6EYD|rcsb pdb:6F6W|refseq:WP_011728783.1|rcsb pdb:5TW1|refseq:YP_887369.1|interpro:IPR003716(RNA polymerase, omega subunit)|interpro:IPR006110(RNA polymerase Rpb6)|interpro:IPR012293(RNA polymerase subunit, RPB6/omega)|rcsb pdb:5VI8|interpro:IPR036161|rcsb pdb:5VI5|rcsb pdb:6CCE|rcsb pdb:6CCV|rcsb pdb:6VVS|rcsb pdb:6VVT|rcsb pdb:6VVV|rcsb pdb:6YXU|rcsb pdb:6YYS|rcsb pdb:6Z11 - - - figure legend:figure 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2012/11/30 2014/10/16 rogid:Pkutghv69DKlB576wJaRXQa3OJI246196 rogid:pDTr+hzDkUHXaI4sVx6A7yeUCTI246196 intact-crc:E0800E00E070CFB0|rigid:sb+D0/zM7OWCbgxNZhwIobflNa4 false his tag:?-? - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:A0R5S2 uniprotkb:P60281 intact:EBI-6417840|ensemblbacteria:ABK71925 intact:EBI-2408357|uniprotkb:A0QS65|uniprotkb:I7G3Q0|ensemblbacteria:ABK70312|ensemblbacteria:AFP37801 psi-mi:a0r5s2_mycs2(display_long)|uniprotkb:MSMEG_6292(locus name) psi-mi:rpob_mycs2(display_long)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:MSMEG_1367(locus name)|uniprotkb:MSMEI_1328(locus name) psi-mi:"MI:0096"(pull down) China et al. (2012) pubmed:22194445|imex:IM-18438 taxid:246196(mycs2)|taxid:246196("Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)") taxid:246196(mycs2)|taxid:246196("Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)") psi-mi:"MI:0914"(association) psi-mi:"MI:0903"(mpidb) intact:EBI-6417836|mpidb:MPIDB-INT-1778|imex:IM-18438-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblbacteria:ABK71925(transcript)|ensemblbacteria:MSMEG_6292(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR001437(Transcription elongation factor, GreA/GreB region, prokaryotic)|interpro:IPR018151|interpro:IPR023459|refseq:YP_890510.1|refseq:WP_003897712.1|interpro:IPR036953 rcsb pdb:6EYD|rcsb pdb:6F6W|rcsb pdb:6DCF|interpro:IPR037033|interpro:IPR037034|refseq:YP_885753.1|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR019462|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|rcsb pdb:5TW1|refseq:WP_011727628.1|rcsb pdb:5VI8|rcsb pdb:5VI5|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6CCE|rcsb pdb:6CCV|interpro:IPR042107|rcsb pdb:6VVS|rcsb pdb:6VVT|rcsb pdb:6VVV|rcsb pdb:6YXU|rcsb pdb:6YYS|rcsb pdb:6Z11|ensemblbacteria:ABK70312(transcript)|ensemblbacteria:AFP37801(transcript)|ensemblbacteria:MSMEG_1367(gene)|ensemblbacteria:MSMEI_1328(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046677"(response to antibiotic) - - - figure legend:figure 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2012/11/30 2014/10/16 rogid:Pkutghv69DKlB576wJaRXQa3OJI246196 rogid:mUxhD0oab8mFtPElhEZK1+eRm7g246196 intact-crc:E0800E00E070CFB0|rigid:sb+D0/zM7OWCbgxNZhwIobflNa4 false his tag:?-? - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P9WKW7 uniprotkb:P9WGY7 intact:EBI-6417806|uniprotkb:P65095|uniprotkb:P72054|uniprotkb:L0TF93 intact:EBI-6429487|uniprotkb:P0A674|uniprotkb:O06771|uniprotkb:P47769|uniprotkb:L0T4I2 psi-mi:y3788_myctu(display_long)|uniprotkb:MTCY13D12.22(orf name)|uniprotkb:Rv3788(locus name) psi-mi:rpoc_myctu(display_long)|uniprotkb:rpoC(gene name)|psi-mi:rpoC(display_short)|uniprotkb:RNA polymerase subunit beta'(gene name synonym)|uniprotkb:Transcriptase subunit beta'(gene name synonym)|uniprotkb:MTCI376.07c(orf name)|uniprotkb:Rv0668(locus name) psi-mi:"MI:0096"(pull down) China et al. (2012) pubmed:22194445|imex:IM-18438 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0914"(association) psi-mi:"MI:0903"(mpidb) intact:EBI-6417855|mpidb:MPIDB-INT-1777|imex:IM-18438-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006354"(DNA-templated transcription, elongation)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR001437(Transcription elongation factor, GreA/GreB region, prokaryotic)|interpro:IPR023459|refseq:NP_218305.1|refseq:WP_003420624.1|interpro:IPR036953 rcsb pdb:6BZO|rcsb pdb:6C04|rcsb pdb:6C05|rcsb pdb:6TYE|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|rcsb pdb:6C06|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0|rcsb pdb:6FBV|refseq:WP_003403413.1|rcsb pdb:6TYF|rcsb pdb:6TYG|refseq:NP_215182.1|interpro:IPR012754(DNA-directed RNA polymerase, subunit beta-prime)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|rcsb pdb:5UH5|rcsb pdb:5UH6|rcsb pdb:5UH7|rcsb pdb:5UH8|rcsb pdb:5UH9|rcsb pdb:5UHA|rcsb pdb:5UHB|rcsb pdb:5UHC|rcsb pdb:5UHD|rcsb pdb:5UHE|rcsb pdb:5UHF|rcsb pdb:5UHG|rcsb pdb:5ZX2|rcsb pdb:5ZX3|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|rcsb pdb:6M7J|interpro:IPR038120|rcsb pdb:6JCX|rcsb pdb:6JCY|interpro:IPR042102|rcsb pdb:6DV9|rcsb pdb:6DVB|rcsb pdb:6DVC|rcsb pdb:6DVD|rcsb pdb:6DVE|reactome:R-HSA-9639775|rcsb pdb:6KON|rcsb pdb:6KOO|rcsb pdb:6KOP|rcsb pdb:6KOQ - - - figure legend:figure 2, 6C, 7|comment:Mycobacterium tuberculosis GreA protein competes for binding to RNAP with Rv3788|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2012/11/30 2014/10/16 rogid:wGNgFcgR7pRh4A7IvpnxbI6qLvw83332 rogid:QoDUBgmHeTU4+HwWBYkj21i1Doc83332 intact-crc:F553EB26E934F2FD|rigid:vG6gL8I7Mhswlr/3VJNJlBjT+e8 false mutation disrupting interaction:126-126|his tag:?-? - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P9WKW7 uniprotkb:P9WGY5 intact:EBI-6417806|uniprotkb:P65095|uniprotkb:P72054|uniprotkb:L0TF93 intact:EBI-6429563|uniprotkb:P66721|uniprotkb:P71660|uniprotkb:L0T993 psi-mi:y3788_myctu(display_long)|uniprotkb:MTCY13D12.22(orf name)|uniprotkb:Rv3788(locus name) psi-mi:rpoz_myctu(display_long)|uniprotkb:rpoZ(gene name)|psi-mi:rpoZ(display_short)|uniprotkb:RNA polymerase omega subunit(gene name synonym)|uniprotkb:Transcriptase subunit omega(gene name synonym)|uniprotkb:MTCY21B4.07(orf name)|uniprotkb:Rv1390(locus name) psi-mi:"MI:0096"(pull down) China et al. (2012) pubmed:22194445|imex:IM-18438 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0914"(association) psi-mi:"MI:0903"(mpidb) intact:EBI-6417855|mpidb:MPIDB-INT-1777|imex:IM-18438-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006354"(DNA-templated transcription, elongation)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR001437(Transcription elongation factor, GreA/GreB region, prokaryotic)|interpro:IPR023459|refseq:NP_218305.1|refseq:WP_003420624.1|interpro:IPR036953 rcsb pdb:6BZO|rcsb pdb:6C04|rcsb pdb:6C05|rcsb pdb:6C06|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0|rcsb pdb:6FBV|refseq:WP_003407248.1|refseq:NP_215906.1|interpro:IPR003716(RNA polymerase, omega subunit)|interpro:IPR006110(RNA polymerase Rpb6)|interpro:IPR012293(RNA polymerase subunit, RPB6/omega)|rcsb pdb:6TYE|rcsb pdb:6TYF|rcsb pdb:6TYG|rcsb pdb:5UH5|rcsb pdb:5UH6|rcsb pdb:5UH8|rcsb pdb:5UH9|rcsb pdb:5UHA|rcsb pdb:5UHB|rcsb pdb:5UHC|rcsb pdb:5UHD|rcsb pdb:5UHE|rcsb pdb:5UHF|rcsb pdb:5UHG|rcsb pdb:5ZX2|rcsb pdb:5ZX3|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|rcsb pdb:6M7J|interpro:IPR036161|rcsb pdb:6JCX|rcsb pdb:6JCY|rcsb pdb:6DV9|rcsb pdb:6DVB|rcsb pdb:6DVC|rcsb pdb:6DVD|rcsb pdb:6DVE|reactome:R-HSA-9639775|rcsb pdb:6KON|rcsb pdb:6KOO|rcsb pdb:6KOP|rcsb pdb:6KOQ - - - figure legend:figure 2, 6C, 7|comment:Mycobacterium tuberculosis GreA protein competes for binding to RNAP with Rv3788|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2012/11/30 2014/10/16 rogid:wGNgFcgR7pRh4A7IvpnxbI6qLvw83332 rogid:vGl8przz7lgqXNpNmTl5lvScP2o83332 intact-crc:F553EB26E934F2FD|rigid:vG6gL8I7Mhswlr/3VJNJlBjT+e8 false mutation disrupting interaction:126-126|his tag:?-? - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P9WKW7 uniprotkb:P9WGY9 intact:EBI-6417806|uniprotkb:P65095|uniprotkb:P72054|uniprotkb:L0TF93 intact:EBI-6419676|uniprotkb:P0A680|uniprotkb:O08406|uniprotkb:P47766|uniprotkb:Q53424|uniprotkb:Q59564|uniprotkb:Q9X6Q3|uniprotkb:Q9X6U9|uniprotkb:Q9XC82|uniprotkb:Q9XC83|uniprotkb:Q9XC84|uniprotkb:Q9XC85|uniprotkb:L0T4D5 psi-mi:y3788_myctu(display_long)|uniprotkb:MTCY13D12.22(orf name)|uniprotkb:Rv3788(locus name) psi-mi:rpob_myctu(display_long)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:MTCI376.08c(orf name)|uniprotkb:Rv0667(locus name) psi-mi:"MI:0096"(pull down) China et al. (2012) pubmed:22194445|imex:IM-18438 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0914"(association) psi-mi:"MI:0903"(mpidb) intact:EBI-6417855|mpidb:MPIDB-INT-1777|imex:IM-18438-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006354"(DNA-templated transcription, elongation)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR001437(Transcription elongation factor, GreA/GreB region, prokaryotic)|interpro:IPR023459|refseq:NP_218305.1|refseq:WP_003420624.1|interpro:IPR036953 rcsb pdb:6TYE|rcsb pdb:6TYF|rcsb pdb:6TYG|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046677"(response to antibiotic)|rcsb pdb:6BZO|rcsb pdb:6C04|rcsb pdb:6C05|rcsb pdb:6C06|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|rcsb pdb:6FBV|rcsb pdb:5UH9|rcsb pdb:5UHA|rcsb pdb:5UHB|rcsb pdb:5UHC|rcsb pdb:5UHD|rcsb pdb:5UHE|rcsb pdb:5UHF|rcsb pdb:5UHG|refseq:NP_215181.1|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR019462|rcsb pdb:5UH5|rcsb pdb:5UH6|rcsb pdb:5UH8|rcsb pdb:4KBJ|rcsb pdb:4KBM|rcsb pdb:5ZX2|rcsb pdb:5ZX3|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|rcsb pdb:6M7J|interpro:IPR037033|interpro:IPR037034|rcsb pdb:6JCX|rcsb pdb:6JCY|interpro:IPR042107|rcsb pdb:6DV9|rcsb pdb:6DVB|rcsb pdb:6DVC|rcsb pdb:6DVD|rcsb pdb:6DVE|reactome:R-HSA-9639775|rcsb pdb:6KON|rcsb pdb:6KOO|rcsb pdb:6KOP|rcsb pdb:6KOQ - - caution:This sequence has been withdrawn from Uniprot.|crc64:3DA88DEC6A7DF661 figure legend:figure 2, 6C, 7|comment:Mycobacterium tuberculosis GreA protein competes for binding to RNAP with Rv3788|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2012/11/30 2014/10/16 rogid:wGNgFcgR7pRh4A7IvpnxbI6qLvw83332 rogid:GaL4H2m+CFelUZAX0cgfkrQtpiY83332 intact-crc:F553EB26E934F2FD|rigid:vG6gL8I7Mhswlr/3VJNJlBjT+e8 false mutation disrupting interaction:126-126|his tag:?-? - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P9WKW7 uniprotkb:P9WGZ1 intact:EBI-6417806|uniprotkb:P65095|uniprotkb:P72054|uniprotkb:L0TF93 intact:EBI-6417848|uniprotkb:P66701|uniprotkb:O06324|uniprotkb:L0TCT4 psi-mi:y3788_myctu(display_long)|uniprotkb:MTCY13D12.22(orf name)|uniprotkb:Rv3788(locus name) psi-mi:rpoa_myctu(display_long)|uniprotkb:rpoA(gene name)|psi-mi:rpoA(display_short)|uniprotkb:RNA polymerase subunit alpha(gene name synonym)|uniprotkb:Transcriptase subunit alpha(gene name synonym)|uniprotkb:MTCY13E12.10c(orf name)|uniprotkb:Rv3457c(locus name) psi-mi:"MI:0096"(pull down) China et al. (2012) pubmed:22194445|imex:IM-18438 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0914"(association) psi-mi:"MI:0903"(mpidb) intact:EBI-6417855|mpidb:MPIDB-INT-1777|imex:IM-18438-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003677"(DNA binding)|go:"GO:0006354"(DNA-templated transcription, elongation)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR001437(Transcription elongation factor, GreA/GreB region, prokaryotic)|interpro:IPR023459|refseq:NP_218305.1|refseq:WP_003420624.1|interpro:IPR036953 rcsb pdb:6BZO|rcsb pdb:6C04|rcsb pdb:6C05|rcsb pdb:6TYE|rcsb pdb:6TYF|rcsb pdb:6TYG|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005618"(cell wall)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|rcsb pdb:6C06|interpro:IPR036643|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0|rcsb pdb:6FBV|interpro:IPR011260(RNA polymerase, alpha subunit, C-terminal)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR011773(DNA-directed RNA polymerase, alpha subunit)|refseq:NP_217974.1|refseq:WP_003418351.1|interpro:IPR036603|rcsb pdb:5UH5|rcsb pdb:5UH6|rcsb pdb:5UH8|rcsb pdb:5UH9|rcsb pdb:5UHA|rcsb pdb:5UHB|rcsb pdb:5UHC|rcsb pdb:5UHD|rcsb pdb:5UHE|rcsb pdb:5UHF|rcsb pdb:5UHG|rcsb pdb:5ZX2|rcsb pdb:5ZX3|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|rcsb pdb:6JCX|rcsb pdb:6JCY|rcsb pdb:6DV9|rcsb pdb:6DVB|rcsb pdb:6DVC|rcsb pdb:6DVD|rcsb pdb:6DVE|reactome:R-HSA-9639775|rcsb pdb:6KON|rcsb pdb:6KOO|rcsb pdb:6KOP|rcsb pdb:6KOQ - - - figure legend:figure 2, 6C, 7|comment:Mycobacterium tuberculosis GreA protein competes for binding to RNAP with Rv3788|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2012/11/30 2014/10/16 rogid:wGNgFcgR7pRh4A7IvpnxbI6qLvw83332 rogid:LTBkYO0JRDnFzCI5CB7/T6ZQ+LQ83332 intact-crc:F553EB26E934F2FD|rigid:vG6gL8I7Mhswlr/3VJNJlBjT+e8 false mutation disrupting interaction:126-126|his tag:?-? - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)